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Frederik Barkhof

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Christiane Möller; Philip scheltens; Frederik Barkhof; Lize Jiskoot; Adriaan Versteeg; Hugo Vrenken; Wiesje M van der Flier
Different patterns of gray matter atrophy in early- and late-onset Alzheimer's disease.
Betty M Tijms; Wiesje M van der Flier; Alle Meije Wink; Willem de Haan; Philip scheltens; Cornelis J Stam; Frederik Barkhof
Alzheimer's disease: connecting findings from graph theoretical studies of brain networks.
Lies Clerx; Remko de Jong; Lutz Froelich; Harald Hampel; Dirk L Knol; Pablo Lapuerta; Lennart Minthon; Flavio Nobili; Daniel Rueckert; Philip scheltens; Hilkka Soininen; Magdalini Tsolaki; Laura A van de Pol; Ineke A van Rossum; Ronald van Schijndel; Frans Verhey; Pauline Aalten; Frederik Barkhof; Martina Bocchetta; Leah Burns; Lars-Olaf Wahlund; Robin Wolz; Pieter Jelle Visser
Measurements of medial temporal lobe atrophy for prediction of Alzheimer's disease in subjects with mild cognitive impairment.

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2013: Christiane Möller; Philip scheltens; Frederik Barkhof; Lize Jiskoot; Adriaan Versteeg; Hugo Vrenken; Wiesje M van der Flier
Different patterns of gray matter atrophy in early- and late-onset Alzheimer's disease.
Neurobiology of aging 2013;34(8):2014-22.
2013: Betty M Tijms; Wiesje M van der Flier; Alle Meije Wink; Willem de Haan; Philip scheltens; Cornelis J Stam; Frederik Barkhof
Alzheimer's disease: connecting findings from graph theoretical studies of brain networks.
Neurobiology of aging 2013;34(8):2023-36.
2013: Lies Clerx; Remko de Jong; Lutz Froelich; Harald Hampel; Dirk L Knol; Pablo Lapuerta; Lennart Minthon; Flavio Nobili; Daniel Rueckert; Philip scheltens; Hilkka Soininen; Magdalini Tsolaki; Laura A van de Pol; Ineke A van Rossum; Ronald van Schijndel; Frans Verhey; Pauline Aalten; Frederik Barkhof; Martina Bocchetta; Leah Burns; Lars-Olaf Wahlund; Robin Wolz; Pieter Jelle Visser
Measurements of medial temporal lobe atrophy for prediction of Alzheimer's disease in subjects with mild cognitive impairment.
Neurobiology of aging 2013;34(8):2003-13.
2013: Bob W van Oosten; Frederik Barkhof; Joep Killestein; Chris H Polman; Mike P Wattjes
PML in a patient treated with dimethyl fumarate from a compounding pharmacy.
The New England journal of medicine 2013;368(17):1658-9.
2013: Maja A A Binnewijzend; Joost P A Kuijer; Philip scheltens; Bart N M Van Berckel; Wiesje M van der Flier; Mike P Wattjes; Alle Meije Wink; Marije R Benedictus; Frederik Barkhof
Cerebral blood flow measured with 3D pseudocontinuous arterial spin-labeling MR imaging in Alzheimer disease and mild cognitive impairment: a marker for disease severity.
Radiology 2013;267(1):221-30.
2013: Anke Vennegoor; Gertjan Wolbink; Lisanne J Balk; Frederik Barkhof; Chris H Polman; Theo Rispens; Alexandra Seewann; Eva Mm Strijbis; Bernard Mj Uitdehaag; Joep Killestein
Clinical relevance of serum natalizumab concentration and anti-natalizumab antibodies in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2013;19(5):593-600.
2013: Hanneke E Hulst; Chris H Polman; Petra J W Pouwels; Martijn D Steenwijk; Bernard M J Uitdehaag; Adriaan Versteeg; Hugo Vrenken; Jeroen J G Geurts; Frederik Barkhof
Cognitive impairment in MS: impact of white matter integrity, gray matter volume, and lesions.
Neurology 2013;80(11):1025-32.
2013: Annapaola Prestia; Philip scheltens; Michael Schöll; Charlotte E Teunissen; Bart Van Berckel; Wiesje M van der Flier; Anders E Wall; Frederik Barkhof; Anna Caroli; Stephen F Carter; Il Han Choo; Agneta Nordberg; Rik Ossenkoppele; Giovanni B Frisoni
Prediction of dementia in MCI patients based on core diagnostic markers for Alzheimer disease.
Neurology 2013;80(11):1048-56.
2013: Richard Dodel; Martin Farlow; Stefan Förster; Jerome Goldstein; Stefan Haag; Michael Jacoby; Judith Alferink; Piero Antuono; Jan-Philipp Bach; Frederik Barkhof; Peter Bartenstein; Kaj Blennow; Katharina Buerger; Isaac Melamed; Markus Otto; Julius Popp; Ralph Richter; Axel Rominger; James Stevens; Stefan Wietek; Jens Wiltfang; Yaroslav Winter; Frank Jessen
Intravenous immunoglobulin for treatment of mild-to-moderate Alzheimer's disease: a phase 2, randomised, double-blind, placebo-controlled, dose-finding trial.
Lancet neurology 2013;12(3):233-43.
2013: Eva M M Strijbis; Bernard M J Uitdehaag; Maria Vounou; Frederik Barkhof; Becky Inkster; Ludwig Kappos; Paul M Matthews; Giovanni Montana; Yvonne Naegelin; Chris H Polman; Ernst-Wilhelm Radue; Jeroen J G Geurts
Glutamate gene polymorphisms predict brain volumes in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2013;19(3):281-8.
2013: Gerke S Grooters; J T H van Asseldonk; Marjo S van der Knaap; Leo H Visser; Frederik Barkhof; Dragos A Nita
Mystery case: Baló concentric sclerosis.
Neurology 2013;80(7):e71-2; discussion e72.
2013: Wolter L de Graaf; Jeroen J G Geurts; Iris D Kilsdonk; Alexandra Lopez-Soriano; Peter R Luijten; Chris H Polman; Petra J W Pouwels; Fredy Visser; Frederik Barkhof; Jonas A Castelijns; Jaco J M Zwanenburg; Mike P Wattjes
Clinical application of multi-contrast 7-T MR imaging in multiple sclerosis: increased lesion detection compared to 3 T confined to grey matter.
European radiology 2013;23(2):528-40.
2013: Rik Ossenkoppele; Philip scheltens; Wiesje M van der Flier; Albert D Windhorst; Marissa D Zwan; Sofie F Adriaanse; Frederik Barkhof; Ronald Boellaard; Adriaan A Lammertsma; Bart N M Van Berckel
Differential effect of APOE genotype on amyloid load and glucose metabolism in AD dementia.
Neurology 2013;80(4):359-65.
2013: Antonio Giorgio; Maria Assunta Rocca; Alex Rovira; Mar Tintore; Ronald van Schijndel; Martina Absinta; Frederik Barkhof; Marco Battaglini; Declan T Chard; Olga Ciccarelli; Alessandro De Leucio; Nicola de Stefano; Christian Enzinger; Massimo Filippi; Jette Frederiksen; Claudio Gasperini
Location of brain lesions predicts conversion of clinically isolated syndromes to multiple sclerosis.
Neurology 2013;80(3):234-41.
2013: Betty M Tijms; Wiesje M van der Flier; Hugo Vrenken; Alle Meije Wink; Willem de Haan; Christiane Möller; Philip scheltens; Cornelis J Stam; Frederik Barkhof
Single-subject grey matter graphs in Alzheimer's disease.
PloS one 2013;8(3):e58921.
2013: Annelies E van der Vlies; Hugo Vrenken; Faiza Admiraal-Behloul; Frederik Barkhof; Niels D Prins; Johan H C Reiber; Philip scheltens; Salka Staekenborg; Wiesje M van der Flier
Associations between magnetic resonance imaging measures and neuropsychological impairment in early and late onset alzheimer's disease.
Journal of Alzheimer's disease : JAD 2013;35(1):169-78.
2013: Madeleine H Sombekke; Bernard M J Uitdehaag; Hugo Vrenken; Mike P Wattjes; Lisanne J Balk; Jessica M Nielsen; Chris H Polman; Frederik Barkhof
Spinal cord lesions in patients with clinically isolated syndrome: a powerful tool in diagnosis and prognosis.
Neurology 2013;80(1):69-75.
2013: Becky Inkster; Ludwig Kappos; Paul M Matthews; Giovanni Montana; Chris H Polman; Ernst-Wilhelm Radue; Eva M M Strijbis; Bernard M J Uitdehaag; Maria Vounou; Frederik Barkhof; Jeroen J G Geurts
Histone deacetylase gene variants predict brain volume changes in multiple sclerosis.
Neurobiology of aging 2013;34(1):238-47.
2013: Alie Schuitemaker; Thalia F van der Doef; Wiesje M van der Flier; Albert D Windhorst; Frederik Barkhof; Ronald Boellaard; Cees Jonker; Reina W Kloet; Dirk L Knol; Marc A Kropholler; Adriaan A Lammertsma; Gert Luurtsema; Philip scheltens; Bart N M Van Berckel
Microglial activation in Alzheimer's disease: an (R)-[¹¹C]PK11195 positron emission tomography study.
Neurobiology of aging 2013;34(1):128-36.
2013: Manja Lehmann; Philip scheltens; Jonathan M Schott; Mike P Wattjes; Frederik Barkhof; Josephine Barnes; Jonathan W Bartlett; Nick C Fox; Esther L Koedam
Visual ratings of atrophy in MCI: prediction of conversion and relationship with CSF biomarkers.
Neurobiology of aging 2013;34(1):73-82.
2013: Menno M Schoonheim; Marieke L van der Meer; Hugo Vrenken; Frederik Barkhof; Linda Douw; Jeroen J G Geurts; Doriana Landi; Chris H Polman; Cornelis J Stam
Functional connectivity changes in multiple sclerosis patients: a graph analytical study of MEG resting state data.
Human brain mapping 2013;34(1):52-61.
2012: Joanna D Schaafsma; Marieke E Sprengers; René van den Berg; Willem-Jan van Rooij; Birgitta K Velthuis; Frederik Barkhof; Joost C J Bot; Patrick A Brouwer; Gerard A P de Kort; Omid Eshghi; Rob T H Lo; Charles B L M Majoie; Gabriël J E Rinkel
Coil-treated aneurysms: decision making regarding additional treatment based on findings of MR angiography and intraarterial DSA.
Radiology 2012;265(3):858-63.
2012: Mike P Wattjes; Frederik Barkhof
Diagnostic relevance of high field MRI in clinical neuroradiology: the advantages and challenges of driving a sports car.
European radiology 2012;22(11):2304-6.
2012: Lukas Filli; Achim Gass; Louis Hofstetter; Ludwig Kappos; Pascal Kuster; Nicole Mueller-Lenke; Yvonne Naegelin; Thomas E Nichols; Chris Polman; Ernst-Wilhelm Radue; Till Sprenger; Stefan Traud; Hugo Vrenken; Frederik Barkhof; Stefan J Borgwardt; Kerstin Bendfeldt
Spatiotemporal distribution of white matter lesions in relapsing-remitting and secondary progressive multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2012;18(11):1577-84.
2012: Menno M Schoonheim; Hugo Vrenken; Oliver T Wiebenga; Linda Douw; Jeroen J G Geurts; Chris H Polman; Veronica Popescu; Fernanda C Rueda Lopes; Frederik Barkhof
Subcortical atrophy and cognition: sex effects in multiple sclerosis.
Neurology 2012;79(17):1754-61.
2012: Ineke A van Rossum; Frans Verhey; Stephanie J B Vos; Lars-Olof Wahlund; Robin Wolz; Frederik Barkhof; Kaj Blennow; Leah Burns; Harald Hampel; Dirk L Knol; Gilbert L'italien; Lennart Minthon; Daniel Rueckert; Philip scheltens; Hilkka Soininen; Charlotte E Teunissen; Magda Tsolaki; Wiesje M van der Flier; Pieter Jelle Visser
Injury markers predict time to dementia in subjects with MCI and amyloid pathology.
Neurology 2012;79(17):1809-16.
2012: Reinhold Schmidt; Wiesje M van der Flier; Ana Verdelho; Lars-Olof Wahlund; Gunhild Waldemar; Anders Wallin; Frederik Barkhof; Andrea Berghold; Timo Erkinjuntti; Franz Fazekas; José M Ferro; Alida A Gouw; Domenico Inzitari; Hanna Jokinen; Sofia Madureira; Leonardo Pantoni; Katja Petrovic; Anna Poggesi; Philip scheltens
White matter lesion progression in LADIS: frequency, clinical effects, and sample size calculations.
Stroke; a journal of cerebral circulation 2012;43(10):2643-7.
2012: Iris-Katharina Penner; Dirk Pleimes; Christoph Pohl; Chris H Polman; Brigitte Stemper; Frederik Barkhof; Pasquale Calabrese; Gilles Edan; Mark S Freedman; Hans-Peter Hartung; Ludwig Kappos; Vivian Lanius; David H Miller; Xavier Montalbán; Rupert Sandbrink
Effects of interferon beta-1b on cognitive performance in patients with a first event suggestive of multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2012;18(10):1466-71.
2012: Stephanie Vos; Lars-Olof Wahlund; Robin Wolz; Pauline Aalten; Frederik Barkhof; Kaj Blennow; Leah Burns; Harald Hampel; Ron Handels; Dirk Knol; Gilbert L'Italien; Lennart Minthon; Daniel Rueckert; Philip scheltens; Hilkka Soininen; Charlotte E Teunissen; Magda Tsolaki; Wiesje van der Flier; Ineke van Rossum; Frans Verhey; Pieter Jelle Visser
Test sequence of CSF and MRI biomarkers for prediction of AD in subjects with MCI.
Neurobiology of aging 2012;33(10):2272-81.
2012: Hanneke E Hulst; Chris H Polman; Veronica Popescu; Stefan D Roosendaal; Menno M Schoonheim; Lizanne J S Schweren; Ysbrand D Van der Werf; Leo H Visser; Frederik Barkhof; Jeroen J G Geurts
Functional adaptive changes within the hippocampal memory system of patients with multiple sclerosis.
Human brain mapping 2012;33(10):2268-80.
2012: Maja A A Binnewijzend; Jessica S Damoiseaux; Ernesto Sanz Arigita; Philip scheltens; Menno M Schoonheim; Nicolaas Verwey; Bart N M Van Berckel; Wiesje M van der Flier; Alle Meije Wink; Sofie M Adriaanse; Frederik Barkhof
Resting-state fMRI changes in Alzheimer's disease and mild cognitive impairment.
Neurobiology of aging 2012;33(9):2018-28.
2012: Annelies E van der Vlies; Frederik Barkhof; Jeroen D C Goos; Philip scheltens; Wiesje M van der Flier
Microbleeds do not affect rate of cognitive decline in Alzheimer disease.
Neurology 2012;79(8):763-9.
2012: Charlotte E Teunissen; Frederik Barkhof; Joep Killestein; C H Polman; M Sombekke; Lisa van Winsen; M A Blankenstein; Christine D Dijkstra; D Pratico
Increased plasma 8,12-iso-iPF2alpha- VI levels in relapsing multiple sclerosis patients are not predictive of disease progression.
Multiple sclerosis (Houndmills, Basingstoke, England) 2012;18(8):1092-8.
2012: V Popescu; I C Sluimer; Bob W van Dijk; Ronald A van Schijndel; S C J Verfaillie; Hugo Vrenken; Frederik Barkhof; Marco Battaglini; Keith S Cover; N de Stefano; W S Hoogstrate; M Jenkinson; Dirk L Knol
Optimizing parameter choice for FSL-Brain Extraction Tool (BET) on 3D T1 images in multiple sclerosis.
NeuroImage 2012;61(4):1484-94.
2012: René M Vigeveno; Mike P Wattjes; Oliver T Wiebenga; Jeroen J G Geurts; Frederik Barkhof
Shifting imaging targets in multiple sclerosis: from inflammation to neurodegeneration.
Journal of magnetic resonance imaging : JMRI 2012;36(1):1-19.
2012: Rik Ossenkoppele; Philip scheltens; Nicolaas Verwey; Danielle M E van Assema; Sofie F Adriaanse; Frederik Barkhof; Ronald Boellaard; Reina W Kloet; Adriaan A Lammertsma; Wiesje M van der Flier; Albert D Windhorst; Marissa D Zwan; Bart N M Van Berckel
Amyloid burden and metabolic function in early-onset Alzheimer's disease: parietal lobe involvement.
Brain : a journal of neurology 2012;135(Pt 7):2115-25.
2012: Eelco van Duinkerken; Michaela Diamant; Richard G IJzerman; Martin Klein; Annette C Moll; Christopher M Ryan; Ernesto J Sanz-Arigita; Menno M Schoonheim; Frank J Snoek; Frederik Barkhof
Resting-state brain networks in type 1 diabetic patients with and without microangiopathy and their relation to cognitive functions and disease variables.
Diabetes 2012;61(7):1814-21.
2012: Frederik Barkhof
Making better use of our brain MRI research data.
European radiology 2012;22(7):1395-6.
2012: Hanna Jokinen; Sofia Madureira; Leonardo Pantoni; Reinhold Schmidt; Hartwig Siebner; Arnold Skimminge; E C W van Straaten; Ana Verdelho; Gunhild Waldemar; Raija Ylikoski; Franz Fazekas; Kristian S Frederiksen; E Garde; Domenico Inzitari; Frederik Barkhof; Timo Erkinjuntti
Callosal tissue loss parallels subtle decline in psychomotor speed. a longitudinal quantitative MRI study. The LADIS Study.
Neuropsychologia 2012;50(7):1650-5.
2012: Rik Ossenkoppele; Philip scheltens; Nicolaas Verwey; Sofie Maria Adriaanse; Frederik Barkhof; Ronald Boellaard; Jessica C Foster-Dingley; Adriaan A Lammertsma; Wiesje M van der Flier; Albert D Windhorst; Maqsood Yaqub; Bart N M Van Berckel
Longitudinal imaging of Alzheimer pathology using [11C]PIB, [18F]FDDNP and [18F]FDG PET.
European journal of nuclear medicine and molecular imaging 2012;39(6):990-1000.
2012: Marjan E Steenweg; Adeline Vanderver; Frederik Barkhof; Berten Ceulemans; Aviva Fattal-Valevski; Petra J W Pouwels; Prab Prabhakar; Luc Régal; Lawrence Richer; Richard J T Rodenburg; Barbara Goeggel Simonetti; Marjo S van der Knaap
Novel infantile-onset leukoencephalopathy with high lactate level and slow improvement.
Archives of neurology 2012;69(6):718-22.
2012: Hannemieke D W van der Lei; Wessel N van Wieringen; Inge M Vent; Frederik Barkhof; Marianna Bugiani; Petra J W Pouwels; Marjan E Steenweg; Marjo S van der Knaap
Restricted diffusion in vanishing white matter.
Archives of neurology 2012;69(6):723-7.
2012: Alie Schuitemaker; Frederik Barkhof; Ronald Boellaard; Cees Jonker; Reina W Kloet; Adriaan A Lammertsma; Philip scheltens; Thalia F van der Doef; Wiesje M van der Flier; Albert D Windhorst; Maqsood Yaqub; Bart N M Van Berckel
Microglial activation in healthy aging.
Neurobiology of aging 2012;33(6):1067-72.
2012: Hanna Jokinen; J Lipsanen; Sofia Madureira; Leonardo Pantoni; Reinhold Schmidt; Wiesje M van der Flier; Ana Verdelho; Anders Wallin; Frederik Barkhof; Timo Erkinjuntti; Franz Fazekas; José M Ferro; Alida A Gouw; Domenico Inzitari
Brain atrophy accelerates cognitive decline in cerebral small vessel disease: the LADIS study.
Neurology 2012;78(22):1785-92.
2012: Iris D Kilsdonk; Frederik Barkhof; Wolter L de Graaf; Mike P Wattjes
Inflammation high-field magnetic resonance imaging.
Neuroimaging clinics of North America 2012;22(2):135-57, ix.
2012: Jeroen D C Goos; Philip scheltens; Charlotte E Teunissen; Frederik Barkhof; Marinus A Blankenstein; Robert Veerhuis; Nicolaas A Verwey; Wiesje M van der Flier
Microbleeds relate to altered amyloid-β metabolism in Alzheimer's disease.
Neurobiology of aging 2012;33(5):1011.e1-9.
2012: Kerstin Bendfeldt; Frederik Barkhof; Achim Gass; Jeroen J G Geurts; Louis Hofstetter; Ludwig Kappos; Pascal Kuster; Nicole Mueller-Lenke; Yvonne Naegelin; Thomas E Nichols; Ernst-Wilhelm Radue; Stefan D Roosendaal; Stefan Traud; Hugo Vrenken; Stefan J Borgwardt
Longitudinal gray matter changes in multiple sclerosis--differential scanner and overall disease-related effects.
Human brain mapping 2012;33(5):1225-45.
2012: Henrica M A de Bie; Henriette A Delemarre-Van De Waal; Kim J Oostrom; Stefan D Roosendaal; Sofie Maria Adriaanse; Frederik Barkhof; Maria Boersma; Cornelis J Stam; Dick J Veltman; Alle Meije Wink; Ernesto Sanz Arigita
Resting-state networks in awake five- to eight-year old children.
Human brain mapping 2012;33(5):1189-201.
2012: Egill Rostrup; E C W van Straaten; Hugo Vrenken; Gunhild Waldemar; Frederik Barkhof; A A Gouw; D Inzitari; L Pantoni; Stefan Ropele
The spatial distribution of age-related white matter changes as a function of vascular risk factors--results from the LADIS study.
NeuroImage 2012;60(3):1597-607.
2012: Massimo Filippi; Jeroen J G Geurts; Hans Lassmann; Claudia Lucchinetti; David H Miller; Daniel Pelletier; Bogdan F Gh Popescu; Maria A Rocca; Frederik Barkhof; Wolfgang Brück; Jacqueline T Chen; Giancarlo Comi; Nicola de Stefano; Gabriele DeLuca; Bradley J Erickson; Nikos Evangelou; Franz Fazekas
Association between pathological and MRI findings in multiple sclerosis.
Lancet neurology 2012;11(4):349-60.
2012: Manja Lehmann; Y A L Pijnenburg; Natalie S Ryan; Philip scheltens; Mike P Wattjes; Frederik Barkhof; Josephine Barnes; Jonathan W Bartlett; Esther L G E Koedam; Nick C Fox
Posterior cerebral atrophy in the absence of medial temporal lobe atrophy in pathologically-confirmed Alzheimer's disease.
Neurobiology of aging 2012;33(3):627.e1-627.e12.
2012: Hannemieke D van der Lei; Nicole Wolf; Frederik Barkhof; Ton de Grauw; Marc d'Hooghe; Richard Morton; Siddharth Shah; Marjan E Steenweg; Marjo S van der Knaap
Characteristics of early MRI in children and adolescents with vanishing white matter.
Neuropediatrics 2012;43(1):22-6.
2012: Susanne Ostrowitzki; Lennart Thurfjell; Zhi-Xin Xu; Kisook Yoo; Elizabeth Ashford; Frederik Barkhof; Bernd Bohrmann; David J Brooks; D Deptula; William E Klunk; Hansruedi Loetscher; Luca Santarelli
Mechanism of amyloid removal in patients with Alzheimer disease treated with gantenerumab.
Archives of neurology 2012;69(2):198-207.
2012: Menno M Schoonheim; Cornelis J Stam; Hugo Vrenken; Frederik Barkhof; Olga Ciccarelli; Hanneke E Hulst; Doriana Landi; Chris H Polman; Stefan D Roosendaal; Ernesto Sanz Arigita; Jeroen J G Geurts
Gender-related differences in functional connectivity in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2012;18(2):164-73.
2012: Alle Meije Wink; Jan C de Munck; Odile A van den Heuvel; Ysbrand D Van der Werf; Frederik Barkhof
Fast eigenvector centrality mapping of voxel-wise connectivity in functional magnetic resonance imaging: implementation, validation, and interpretation.
Brain connectivity 2012;2(5):265-74.
2012: Martin Hardmeier; Arjan Hillebrand; Chris H Polman; Menno M Schoonheim; Frederik Barkhof; Jeroen J G Geurts; Cornelis J Stam
Cognitive dysfunction in early multiple sclerosis: altered centrality derived from resting-state functional connectivity using magneto-encephalography.
PloS one 2012;7(7):e42087.
2012: E C W van Straaten; Wiesje M van der Flier; Frederik Barkhof; Willem de Haan; Hanneke De Waal; Ted Koene; Philip scheltens; Cornelis Stam
Disturbed oscillatory brain dynamics in subcortical ischemic vascular dementia.
BMC neuroscience 2012;13():85.
2012: David Wilkinson; Frederik Barkhof; Nick C Fox; Ole Lemming; Ravinder Phul; Philip scheltens
Memantine and brain atrophy in Alzheimer's disease: a 1-year randomized controlled trial.
Journal of Alzheimer's disease : JAD 2012;29(2):459-69.
2012: Ineke A van Rossum; Pieter Jelle Visser; Charlotte E Teunissen; Wiesje M van der Flier; Frederik Barkhof; Marinus A Blankenstein; Dirk L Knol; Philip scheltens
Injury markers but not amyloid markers are associated with rapid progression from mild cognitive impairment to dementia in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2012;29(2):319-27.
2012: Wolter L de Graaf; Jeroen J G Geurts; Peter R Luijten; Chris H Polman; Petra J W Pouwels; Fredy Visser; Mike P Wattjes; Jaco J M Zwanenburg; Frederik Barkhof; Jonas A Castelijns
Lesion detection at seven Tesla in multiple sclerosis using magnetisation prepared 3D-FLAIR and 3D-DIR.
European radiology 2012;22(1):221-31.
2011: Esther L G E Koedam; Manja Lehmann; Y A L Pijnenburg; Philip scheltens; Wiesje M van der Flier; Frederik Barkhof; Nick Fox; Mike P Wattjes
Visual assessment of posterior atrophy development of a MRI rating scale.
European radiology 2011;21(12):2618-25.
2011: Ludwig Kappos; David Leppert; David Li; Paul O'Connor; Jeroen Tinbergen; Ming Yin; Frederik Barkhof; Amit Bar-Or; Peter A Calabresi; Robert Glanzman; Stephen L Hauser
Ocrelizumab in relapsing-remitting multiple sclerosis: a phase 2, randomised, placebo-controlled, multicentre trial.
Lancet 2011;378(9805):1779-87.
2011: Marianne E Steenweg; Frederik Barkhof; Petra J W Pouwels; Wessel N van Wieringen; Nicole I Wolf; Marjo S van der Knaap
Leucoencephalopathy with brainstem and spinal cord involvement and high lactate: quantitative magnetic resonance imaging.
Brain : a journal of neurology 2011;134(Pt 11):3333-41.
2011: Alexandra Seewann; Paul Van Der Valk; Hugo Vrenken; Frederik Barkhof; Dirk L Knol; Evert-Jan Kooi; Chris H Polman; Petra J W Pouwels; Jeroen J G Geurts
Imaging the tip of the iceberg: visualization of cortical lesions in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2011;17(10):1202-10.
2011: Maria Liguori; Dominik Meier; Howard L Weiner; Brian C Healy; Peter Hildenbrand; Samia J Khoury; Rohit Bakshi; Frederik Barkhof; Natalie F Baruch; Tanuja Chitnis; Charles R G Guttmann
One year activity on subtraction MRI predicts subsequent 4 year activity and progression in multiple sclerosis.
Journal of neurology, neurosurgery, and psychiatry 2011;82(10):1125-31.
2011: Keith S Cover; Giovanni B Frisoni; Dirk L Knol; Alberto Redolfi; Bob W van Dijk; Ronald A van Schijndel; Hugo Vrenken; Frederik Barkhof
Assessing the reproducibility of the SienaX and Siena brain atrophy measures using the ADNI back-to-back MP-RAGE MRI scans.
Psychiatry research 2011;193(3):182-90.
2011: Marieke Hazewinkel; Frederik Barkhof
Imaging Alzheimer in 2011.
Neuroradiology 2011;53 Suppl 1():S145-7.
2011: Stefan D Roosendaal; Hugo Vrenken; Frederik Barkhof; Kerstin Bendfeldt; Stefan Borgwardt; Stephen L Hauser; Ludwig Kappos; Paul Matthews; Daniel Pelletier; Chris H Polman; Ernst W Radue; Jeroen J G Geurts
Grey matter volume in a large cohort of MS patients: relation to MRI parameters and disability.
Multiple sclerosis (Houndmills, Basingstoke, England) 2011;17(9):1098-106.
2011: Hans-Peter Hartung; Ludwig Kappos; Volker Knappertz; V Lanius; David H Miller; Xavier Montalbán; John Petkau; C Pohl; Chris H Polman; V Sahajpal; Rupert Sandbrink; Rick White; Frederik Barkhof; Karola Beckmann; Gilles Edan; Mark S Freedman
Interferon β-1b-neutralizing antibodies 5 years after clinically isolated syndrome.
Neurology 2011;77(9):835-43.
2011: Charlotte Ryberg; Philip scheltens; Reinhold Schmidt; Wiesje M van der Flier; E C W van Straaten; Lars-Olof Wahlund; Gunhild Waldemar; Hansjoerg Baezner; Frederik Barkhof; Timo Erkinjuntti; Franz Fazekas; José M Ferro; Domenico Inzitari; Hanna Jokinen; Leonardo Pantoni; Olaf B Paulson; A Poggesi; Egill Rostrup
Corpus callosum atrophy as a predictor of age-related cognitive and motor impairment: a 3-year follow-up of the LADIS study cohort.
Journal of the neurological sciences 2011;307(1-2):100-5.
2011: Clifford R Jack; Keith Johnson; Jean-François Mangin; Philip scheltens; Adam J Schwarz; Reisa Sperling; Joyce Suhy; Paul M Thompson; Michael Weiner; Frederik Barkhof; Matt A Bernstein; Marc Cantillon; Patricia E Cole; Charles DeCarli; Bruno Dubois; Simon Duchesne; Nick C Fox; Giovanni B Frisoni; Harald Hampel; Derek L G Hill; Norman L Foster
Steps to standardization and validation of hippocampal volumetry as a biomarker in clinical trials and diagnostic criterion for Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2011;7(4):474-485.e4.
2011: Iris D Kilsdonk; Frederik Barkhof; Mike P Wattjes
2010 revisions to McDonald criteria for diagnosis of multiple sclerosis: impact of 3-Tesla magnetic resonance imaging.
Annals of neurology 2011;70(1):182-3.
2011: Stefan Ropele; Alex Rovira; Mike P Wattjes; Frederik Barkhof; Wolter de Graaf; Massimo Filippi; Michael Khalil; Christian Langkammer; Jacqueline Palace; Maria A Rocca; Franz Fazekas
MRI assessment of iron deposition in multiple sclerosis.
Journal of magnetic resonance imaging : JMRI 2011;34(1):13-21.
2011: Jeroen D C Goos; Dirk L Knol; Petra J W Pouwels; Philip scheltens; Wiesje M van der Flier; Frederik Barkhof; Mike P Wattjes
Clinical relevance of improved microbleed detection by susceptibility-weighted magnetic resonance imaging.
Stroke; a journal of cerebral circulation 2011;42(7):1894-900.
2011: Sinan M K Belhawi; Friso W A Hoefnagels; Johannes C Baaijen; Jaap C Reijneveld; Jan J Heimans; Frederik Barkhof; W Peter Vandertop; Esther Sanchez Aliaga; Philip C de Witt Hamer
Early postoperative MRI overestimates residual tumour after resection of gliomas with no or minimal enhancement.
European radiology 2011;21(7):1526-34.
2011: Bhupendra Khatri; Xavier Montalban; Jean Pelletier; Tracy Stites; Stacy Wu; Lixin Zhang-Auberson; Frederik Barkhof; Jeffrey A Cohen; Giancarlo Comi; Gordon Francis; Hans-Peter Hartung; Fred Holdbrook; Ludwig Kappos
Comparison of fingolimod with interferon beta-1a in relapsing-remitting multiple sclerosis: a randomised extension of the TRANSFORMS study.
Lancet neurology 2011;10(6):520-9.
2011: Hanna Jokinen; Sofia Madureira; Leonardo Pantoni; Philip scheltens; Reinhold Schmidt; Wiesje M van der Flier; E C W van Straaten; Ana Verdelho; Raija Ylikoski; Frederik Barkhof; Timo Erkinjuntti; Franz Fazekas; José M Ferro; Alida A Gouw; Domenico Inzitari
Incident lacunes influence cognitive decline: the LADIS study.
Neurology 2011;76(22):1872-8.
2011: M H Sombekke; N Jafari; K Bendfeldt; N Mueller-Lenke; E W Radue; Y Naegelin; Ludwig Kappos; P M Matthews; Chris H Polman; Frederik Barkhof; Rogier Q Hintzen; J J G Geurts
No influence of KIF1B on neurodegenerative markers in multiple sclerosis.
Neurology 2011;76(21):1843-5.
2011: Paola Valsasina; Maria A Rocca; Martina Absinta; Maria Pia Sormani; Laura Mancini; Nicola de Stefano; Alex Rovira; Achim Gass; Christian Enzinger; Frederik Barkhof; Christiane Wegner; Paul Matthews; Massimo Filippi
A multicentre study of motor functional connectivity changes in patients with multiple sclerosis.
The European journal of neuroscience 2011;33(7):1256-63.
2011: Mike P Wattjes; Bob W van Oosten; Wolter L de Graaf; Alexandra Seewann; Joost C J Bot; René van den Berg; Bernard M J Uitdehaag; Chris H Polman; Frederik Barkhof
No association of abnormal cranial venous drainage with multiple sclerosis: a magnetic resonance venography and flow-quantification study.
Journal of neurology, neurosurgery, and psychiatry 2011;82(4):429-35.
2011: Ronald B Willemse; Petra J W Pouwels; Frederik Barkhof; W Peter Vandertop
Localisation of the central sulcus region in glioma patients with three-dimensional fluid-attenuated inversion recovery and volume rendering: comparison with functional and conventional magnetic resonance.
British journal of neurosurgery 2011;25(2):210-7.
2011: Massimo Filippi; Maria A Rocca; Frederik Barkhof; Rohit Bakshi; Franz Fazekas; OA Khan; D Pelletier; Alex Rovira; J Simon
Multiple sclerosis and chronic cerebrospinal venous insufficiency: the neuroimaging perspective.
AJNR. American journal of neuroradiology 2011;32(3):424-7.
2011: Frederik Barkhof; Petra J W Pouwels; Mike P Wattjes
The Holy Grail in diagnostic neuroradiology: 3T or 3D?
European radiology 2011;21(3):449-56.
2011: Marco Rovaris; Maria A Rocca; Frederik Barkhof; Massimiliano Calabrese; Nicola de Stefano; Michael Khalil; Franz Fazekas; Leonora Fisniku; Paolo Gallo; David H Miller; Xavier Montalban; Chris Polman; Alex Rovira; Madeleine H Sombekke; Maria Pia Sormani; Maria Laura Stromillo; Massimo Filippi
Relationship between brain MRI lesion load and short-term disease evolution in non-disabling MS: a large-scale, multicentre study.
Multiple sclerosis (Houndmills, Basingstoke, England) 2011;17(3):319-26.
2011: Reinhard Hohlfeld; Frederik Barkhof; Chris Polman
Future clinical challenges in multiple sclerosis: Relevance to sphingosine 1-phosphate receptor modulator therapy.
Neurology 2011;76(8 Suppl 3):S28-37.
2011: A Vennegoor; Mike P Wattjes; E T L van Munster; R L Kriekaart; Bob W van Oosten; Frederik Barkhof; Joep Killestein; Chris H Polman
Indolent course of progressive multifocal leukoencephalopathy during natalizumab treatment in MS.
Neurology 2011;76(6):574-6.
2011: R Jeroen Vermeulen; C Peeters-Scholte; J J M G Van Vught; Frederik Barkhof; Patrizia Rizzu; Sophie R D Van Der Schoor; J J M Van Vugt; Marjo S van der Knaap
Fetal origin of brain damage in 2 infants with a COL4A1 mutation: fetal and neonatal MRI.
Neuropediatrics 2011;42(1):1-3.
2011: L Celso Hygino da Cruz; Raquel Ribeiro Batista; Roberto Cortes Domingues; Frederik Barkhof
Diffusion magnetic resonance imaging in multiple sclerosis.
Neuroimaging clinics of North America 2011;21(1):71-88, vii-viii.
2011: Jeroen J G Geurts; S D Roosendaal; M Calabrese; O Ciccarelli; Federica Agosta; D T Chard; A Gass; E Huerga; B Moraal; D Pareto; M A Rocca; Mike P Wattjes; Tarek A Yousry; B M J Uitdehaag; Frederik Barkhof
Consensus recommendations for MS cortical lesion scoring using double inversion recovery MRI.
Neurology 2011;76(5):418-24.
2011: Jim A Reekers; M J Lee; A M Belli; Frederik Barkhof
Cardiovascular and Interventional Radiological Society of Europe commentary on the treatment of chronic cerebrospinal venous insufficiency.
Cardiovascular and interventional radiology 2011;34(1):1-2.
2011: Alida A Gouw; Alexandra Seewann; Wiesje M van der Flier; Frederik Barkhof; Annemieke M Rozemuller; Philip scheltens; Jeroen J G Geurts
Heterogeneity of small vessel disease: a systematic review of MRI and histopathology correlations.
Journal of neurology, neurosurgery, and psychiatry 2011;82(2):126-35.
2011: Kristian S Frederiksen; E Garde; Domenico Inzitari; Hanna Jokinen; John T O'Brien; Leonardo Pantoni; Philip scheltens; Arnold Skimminge; E C W van Straaten; Ana Verdelho; Lars-Olof Wahlund; Hansjoerg Baezner; Frederik Barkhof; Anna Maria Basile; Timo Erkinjuntti; Franz Fazekas; José M Ferro; Gunhild Waldemar
Corpus callosum tissue loss and development of motor and global cognitive impairment: the LADIS study.
Dementia and geriatric cognitive disorders 2011;32(4):279-86.
2011: Jonathan M Schott; Jason D Warren; Frederik Barkhof; Martin N Rossor; Nick C Fox
Suspected early dementia.
BMJ (Clinical research ed.) 2011;343():d5568.
2011: Henrica M A De Bie; Henriette A Delemarre-Van De Waal; Kim J Oostrom; Frederik Barkhof; Maria Boersma; Dick J Veltman; martijn van den heuvel
Global and regional differences in brain anatomy of young children born small for gestational age.
PloS one 2011;6(9):e24116.
2011: Mardien L Oudega; Eric van Exel; Mike P Wattjes; Hannie C Comijs; Philip scheltens; Frederik Barkhof; Piet Eikelenboom; Anton J M de Craen; Aartjan T F Beekman; Max L Stek
White matter hyperintensities, medial temporal lobe atrophy, cortical atrophy, and response to electroconvulsive therapy in severely depressed elderly patients.
The Journal of clinical psychiatry 2011;72(1):104-12.
2011: B Bodini; M Battaglini; Nicola de Stefano; Zhaleh Khaleeli; Frederik Barkhof; Declan T Chard; Massimo Filippi; Xavier Montalban; Chris H Polman; Marco Rovaris; Alex Rovira; R Samson; David Miller; Alan Thompson; Olga Ciccarelli
T2 lesion location really matters: a 10 year follow-up study in primary progressive multiple sclerosis.
Journal of neurology, neurosurgery, and psychiatry 2011;82(1):72-7.
2010: Carsten Lukas; Arjan Minneboo; Vincent de Groot; Bastiaan Moraal; Dirk L Knol; Chris H Polman; Frederik Barkhof; Hugo Vrenken
Early central atrophy rate predicts 5 year clinical outcome in multiple sclerosis.
Journal of neurology, neurosurgery, and psychiatry 2010;81(12):1351-6.
2010: V Worthington; Joep Killestein; M Judith Eikelenboom; Charlotte E Teunissen; Frederik Barkhof; Chris H Polman; B M J Uitdehaag; Axel Petzold
Normal CSF ferritin levels in MS suggest against etiologic role of chronic venous insufficiency.
Neurology 2010;75(18):1617-22.
2010: L F van der Voort; A Vennegoor; A Visser; D L Knol; B M J Uitdehaag; Frederik Barkhof; C B M Oudejans; Chris H Polman; Joep Killestein
Spontaneous MxA mRNA level predicts relapses in patients with recently diagnosed MS.
Neurology 2010;75(14):1228-33.
2010: Marjan E Steenweg; Adeline Vanderver; Susan Blaser; Alberto Bizzi; Tom J de Koning; Grazia M S Mancini; Wessel N van Wieringen; Frederik Barkhof; Nicole I Wolf; Marjo S van der Knaap
Magnetic resonance imaging pattern recognition in hypomyelinating disorders.
Brain : a journal of neurology 2010;133(10):2971-82.
2010: I J van den Elskamp; B Boden; V Dattola; Dirk L Knol; Massimo Filippi; Ludwig Kappos; Franz Fazekas; K Wagner; Christoph Pohl; Rupert Sandbrink; Chris H Polman; B M J Uitdehaag; Frederik Barkhof
Cerebral atrophy as outcome measure in short-term phase 2 clinical trials in multiple sclerosis.
Neuroradiology 2010;52(10):875-81.
2010: Nelleke Tolboom; Wiesje M van der Flier; Jolanda Boverhoff; Maqsood Yaqub; Mike P Wattjes; Pieter G Raijmakers; Frederik Barkhof; Philip scheltens; Karl Herholz; Adriaan A Lammertsma; Bart N M Van Berckel
Molecular imaging in the diagnosis of Alzheimer's disease: visual assessment of [11C]PIB and [18F]FDDNP PET images.
Journal of neurology, neurosurgery, and psychiatry 2010;81(8):882-4.
2010: Nicolaas Verwey; Esther L G E Koedam; Jonathan M Schott; Maqsood Yaqub; Marinus A Blankenstein; Frederik Barkhof; Y A L Pijnenburg; Adriaan A Lammertsma; Philip scheltens; Bart N M Van Berckel
Dementia mimicking Alzheimer's disease Owing to a tau mutation: CSF and PET findings.
Alzheimer disease and associated disorders 2010;24(3):303-7.
2010: Esther L G E Koedam; Wiesje M van der Flier; Frederik Barkhof; Ted Koene; Philip scheltens; Y A L Pijnenburg
Clinical characteristics of patients with frontotemporal dementia with and without lobar atrophy on MRI.
Alzheimer disease and associated disorders 2010;24(3):242-7.
2010: Joanna D Schaafsma; Birgitta K Velthuis; Charles B L M Majoie; René van den Berg; Patrick A Brouwer; Frederik Barkhof; Omid Eshghi; Gerard A P de Kort; Rob T H Lo; Theo D Witkamp; Marieke E Sprengers; Marianne A van Walderveen; Joost C J Bot; Esther Sanchez; W Peter Vandertop; Jan van Gijn; Erik Buskens; Yolanda van der Graaf; G J E Rinkel
Intracranial aneurysms treated with coil placement: test characteristics of follow-up MR angiography--multicenter study.
Radiology 2010;256(1):209-18.
2010: Birgit Simon; Stephan Schmidt; Carsten Lukas; Jürgen Gieseke; Frank Träber; Dirk L Knol; Winfried A Willinek; Jeroen J G Geurts; Hans H Schild; Frederik Barkhof; Mike P Wattjes
Improved in vivo detection of cortical lesions in multiple sclerosis using double inversion recovery MR imaging at 3 Tesla.
European radiology 2010;20(7):1675-83.
2010: J D C Goos; W J P Henneman; J D Sluimer; Hugo Vrenken; I C Sluimer; Frederik Barkhof; Marinus A Blankenstein; Philip scheltens; Wiesje M van der Flier
Incidence of cerebral microbleeds: a longitudinal study in a memory clinic population.
Neurology 2010;74(24):1954-60.
2010: Elisabetta Pagani; Jochen G Hirsch; Petra J W Pouwels; Mark A Horsfield; Elisabetta Perego; Achim Gass; Stefan D Roosendaal; Frederik Barkhof; Federica Agosta; Marco Rovaris; Domenico Caputo; Antonio Giorgio; Jacqueline Palace; Silvia Marino; Nicola de Stefano; Stefan Ropele; Franz Fazekas; Massimo Filippi
Intercenter differences in diffusion tensor MRI acquisition.
Journal of magnetic resonance imaging : JMRI 2010;31(6):1458-68.
2010: Stefan D Roosendaal; Menno M Schoonheim; Hanneke E Hulst; Ernesto Sanz Arigita; Stephen M Smith; Jeroen J G Geurts; Frederik Barkhof
Resting state networks change in clinically isolated syndrome.
Brain : a journal of neurology 2010;133(Pt 6):1612-21.
2010: I J van den Elskamp; D L Knol; H Vrenken; Giorgos Karas; A Meijerman; Massimo Filippi; Ludwig Kappos; Franz Fazekas; Klaus Wagner; Christoph Pohl; Rupert Sandbrink; C H Polman; B M J Uitdehaag; Frederik Barkhof
Lesional magnetization transfer ratio: a feasible outcome for remyelinating treatment trials in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2010;16(6):660-9.
2010: Bastiaan Moraal; Ivo J van den Elskamp; Dirk L Knol; Bernard M J Uitdehaag; Jeroen J G Geurts; Hugo Vrenken; Petra J W Pouwels; Ronald A van Schijndel; Dominik S Meier; Charles R G Guttmann; Frederik Barkhof
Long-interval T2-weighted subtraction magnetic resonance imaging: a powerful new outcome measure in multiple sclerosis trials.
Annals of neurology 2010;67(5):667-75.
2010: Reinhold Schmidt; Stefan Ropele; José Ferro; Sofia Madureira; Ana Verdelho; Katja Petrovic; Alida A Gouw; Wiesje M van der Flier; Christian Enzinger; Leonardo Pantoni; Domenico Inzitari; Timo Erkinjuntti; Philip scheltens; Lars-Olof Wahlund; Gunhild Waldemar; Egill Rostrup; Anders Wallin; Frederik Barkhof; Franz Fazekas
Diffusion-weighted imaging and cognition in the leukoariosis and disability in the elderly study.
Stroke; a journal of cerebral circulation 2010;41(5):e402-8.
2010: Salka Staekenborg; Tanja Su; E C W van Straaten; Roger Lane; Philip scheltens; Frederik Barkhof; Wiesje M van der Flier
Behavioural and psychological symptoms in vascular dementia; differences between small- and large-vessel disease.
Journal of neurology, neurosurgery, and psychiatry 2010;81(5):547-51.
2010: Jasper D Sluimer; Femke H Bouwman; Hugo Vrenken; Marinus A Blankenstein; Frederik Barkhof; Wiesje M van der Flier; Philip scheltens
Whole-brain atrophy rate and CSF biomarker levels in MCI and AD: a longitudinal study.
Neurobiology of aging 2010;31(5):758-64.
2010: Menno M Schoonheim; Jeroen J G Geurts; Frederik Barkhof
The limits of functional reorganization in multiple sclerosis.
Neurology 2010;74(16):1246-7.
2010: Bastiaan Moraal; Mike P Wattjes; Jeroen J G Geurts; Dirk L Knol; Ronald A van Schijndel; Petra J W Pouwels; Hugo Vrenken; Frederik Barkhof
Improved detection of active multiple sclerosis lesions: 3D subtraction imaging.
Radiology 2010;255(1):154-63.
2010: Frederik Barkhof; H E Hulst; J Drulovic; B M J Uitdehaag; K Matsuda; R Landin
Ibudilast in relapsing-remitting multiple sclerosis: a neuroprotectant?
Neurology 2010;74(13):1033-40.
2010: OA Khan; Massimo Filippi; Mark S Freedman; Frederik Barkhof; Paula Dore-Duffy; Hans Lassmann; Bruce Trapp; Amit Bar-Or; Imad Zak; Marilyn J Siegel; Robert P Lisak
Chronic cerebrospinal venous insufficiency and multiple sclerosis.
Annals of neurology 2010;67(3):286-90.
2010: Jeffrey A Cohen; Frederik Barkhof; Giancarlo Comi; Hans-Peter Hartung; Bhupendra O Khatri; Xavier Montalban; Jean Pelletier; Ruggero Capra; Paolo Gallo; Guillermo Izquierdo; Klaus Tiel-Wilck; Ana de Vera; James Jin; Tracy Stites; Stacy Wu; Shreeram Aradhye; Ludwig Kappos
Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis.
The New England journal of medicine 2010;362(5):402-15.
2010: Ernesto Sanz Arigita; Menno M Schoonheim; Jessica S Damoiseaux; Serge A R B Rombouts; Erik Maris; Frederik Barkhof; Philip scheltens; Cornelis Stam
Loss of 'small-world' networks in Alzheimer's disease: graph analysis of FMRI resting-state functional connectivity.
PloS one 2010;5(11):e13788.
2010: Femke H Bouwman; Alie Schuitemaker; Martin Klein; astrid kok; Marinus A Blankenstein; J D Sluimer; Frederik Barkhof; Wiesje M van der Flier; Philip scheltens
New research criteria for the diagnosis of Alzheimer's disease applied in a memory clinic population.
Dementia and geriatric cognitive disorders 2010;30(1):1-7.
2010: Salka Staekenborg; Hanneke De Waal; Faiza Admiraal-Behloul; Frederik Barkhof; J H C Reiber; Philip scheltens; Y A L Pijnenburg; H Vrenken; Wiesje M van der Flier
Neurological signs in relation to white matter hyperintensity volumes in memory clinic patients.
Dementia and geriatric cognitive disorders 2010;29(4):301-8.
2010: Frederik Barkhof
"Benign" and "normal appearing": it's in the eye of the beholder.
Journal of neurology, neurosurgery, and psychiatry 2010;81(1):4.
2010: Mojtaba Zarei; Brian Patenaude; Jessica Damoiseaux; Ciro Morgese; Steve Smith; Paul Matthews; Frederik Barkhof; Serge A R B Rombouts; Ernesto Sanz Arigita; Mark Jenkinson
Combining shape and connectivity analysis: an MRI study of thalamic degeneration in Alzheimer's disease.
NeuroImage 2010;49(1):1-8.
2009: Madeleine H Sombekke; Carsten Lukas; J B A Crusius; Diego Tejedor; Joep Killestein; David Arteta; Antonio Martínez; Bernard M J Uitdehaag; Dirk L Knol; Amado Salvador Peña; Jeroen J G Geurts; Philip L De Jager; Frederik Barkhof; Hugo Vrenken; Chris H Polman
HLA-DRB1*1501 and spinal cord magnetic resonance imaging lesions in multiple sclerosis.
Archives of neurology 2009;66(12):1531-6.
2009: Jasper D Sluimer; Wiesje M van der Flier; Giorgos Karas; Ronald A van Schijndel; Josephine Barnes; Richard G Boyes; Keith S Cover; Sílvia D Olabarriaga; Nick C Fox; Philip scheltens; Hugo Vrenken; Frederik Barkhof
Accelerating regional atrophy rates in the progression from normal aging to Alzheimer's disease.
European radiology 2009;19(12):2826-33.
2009: Bastiaan Moraal; Christoph Pohl; Bernard M J Uitdehaag; Chris H Polman; Gilles Edan; Mark S Freedman; Hans-Peter Hartung; Ludwig Kappos; David H Miller; Xavier Montalban; Vivian Lanius; Rupert Sandbrink; Frederik Barkhof
Magnetic resonance imaging predictors of conversion to multiple sclerosis in the BENEFIT study.
Archives of neurology 2009;66(11):1345-52.
2009: Jeroen D C Goos; M I Kester; Frederik Barkhof; Martin Klein; Marinus A Blankenstein; Philip scheltens; Wiesje M van der Flier
Patients with Alzheimer disease with multiple microbleeds: relation with cerebrospinal fluid biomarkers and cognition.
Stroke; a journal of cerebral circulation 2009;40(11):3455-60.
2009: Ludwig Kappos; Mark S Freedman; Chris H Polman; Gilles Edan; Hans-Peter Hartung; David H Miller; Xavier Montalbán; Frederik Barkhof; Ernst W Radü; Carola Metzig; Lars Bauer; Vivian Lanius; Rupert Sandbrink; Christoph Pohl
Long-term effect of early treatment with interferon beta-1b after a first clinical event suggestive of multiple sclerosis: 5-year active treatment extension of the phase 3 BENEFIT trial.
Lancet neurology 2009;8(11):987-97.
2009: Mike P Wattjes; Wouter J P Henneman; Wiesje M van der Flier; Oscar de Vries; Frank Träber; Jeroen J G Geurts; Philip scheltens; Hugo Vrenken; Frederik Barkhof
Diagnostic imaging of patients in a memory clinic: comparison of MR imaging and 64-detector row CT.
Radiology 2009;253(1):174-83.
2009: Laura A van de Pol; Frans Verhey; Giovanni B Frisoni; M Tsolaki; P Papapostolou; F Nobili; Lars-Olof Wahlund; L Minthon; Lutz Froelich; Harald Hampel; Hilkka Soininen; Dirk L Knol; Frederik Barkhof; Philip scheltens; Pieter Jelle Visser
White matter hyperintensities and medial temporal lobe atrophy in clinical subtypes of mild cognitive impairment: the DESCRIPA study.
Journal of neurology, neurosurgery, and psychiatry 2009;80(10):1069-74.
2009: J Patrick van der Voorn; Petra J W Pouwels; Gajja S Salomons; Frederik Barkhof; Marjo S van der Knaap
Unraveling pathology in juvenile Alexander disease: serial quantitative MR imaging and spectroscopy of white matter.
Neuroradiology 2009;51(10):669-75.
2009: Nicolaas Verwey; Hugo Vrenken; Josephine Barnes; I C Sluimer; Alie Schuitemaker; Marinus A Blankenstein; Martin Klein; Nick C Fox; Philip scheltens; Frederik Barkhof; Wiesje M van der Flier
Baseline CSF p-tau levels independently predict progression of hippocampal atrophy in Alzheimer disease.
Neurology 2009;73(12):935-40.
2009: Tijmen Korteweg; M Tintore; B M J Uitdehaag; Dirk L Knol; Hugo Vrenken; A Rovira; J Frederiksen; David H Miller; K Fernando; Massimo Filippi; F Agosta; M A Rocca; Franz Fazekas; C Enzinger; A Parry; Chris H Polman; Xavier Montalban; Frederik Barkhof
A search for new MRI criteria for dissemination in space in subjects with a clinically isolated syndrome.
European radiology 2009;19(9):2244-8.
2009: J P van der Voorn; J P van der Voom; P J Pouwels; R Pouweis; R Jeroen Vermeulen; Frederik Barkhof; M S van der Knaap; M Van der Knaap
Quantitative MR imaging and spectroscopy in congenital cytomegalovirus infection and periventricular leukomalacia suggests a comparable neuropathological substrate of the cerebral white matter lesions.
Neuropediatrics 2009;40(4):168-73.
2009: Maria A Rocca; Martina Absinta; Paola Valsasina; Olga Ciccarelli; Silvia Marino; Alex Rovira; Achim Gass; Christiane Wegner; Christian Enzinger; Tjimen Korteweg; Maria Pia Sormani; Laura Mancini; Alan J Thompson; Nicola De Stefano; Xavier Montalban; Jochen Hirsch; Ludwig Kappos; Stephan Ropele; Jacqueline Palace; Frederik Barkhof; Paul Matthews; Massimo Filippi
Abnormal connectivity of the sensorimotor network in patients with MS: a multicenter fMRI study.
Human brain mapping 2009;30(8):2412-25.
2009: S D Roosendaal; B Moraal; P J W Pouwels; Hugo Vrenken; J A Castelijns; Frederik Barkhof; J J G Geurts
Accumulation of cortical lesions in MS: relation with cognitive impairment.
Multiple sclerosis (Houndmills, Basingstoke, England) 2009;15(6):708-14.
2009: A Seewann; E-J Kooi; S D Roosendaal; Frederik Barkhof; P van der Valk; Jeroen J G Geurts
Translating pathology in multiple sclerosis: the combination of postmortem imaging, histopathology and clinical findings.
Acta neurologica Scandinavica 2009;119(6):349-55.
2009: Marco Rovaris; Frederik Barkhof; Massimiliano Calabrese; Nicola de Stefano; F Fazekas; David H Miller; Xavier Montalban; Chris H Polman; Maria A Rocca; Alan J Thompson; Tarek A Yousry; Massimo Filippi
MRI features of benign multiple sclerosis: toward a new definition of this disease phenotype.
Neurology 2009;72(19):1693-701.
2009: Frederik Barkhof; Peter A Calabresi; David H Miller; Stephen C Reingold
Imaging outcomes for neuroprotection and repair in multiple sclerosis trials.
Nature reviews. Neurology 2009;5(5):256-66.
2009: Alexandra Seewann; Hugo Vrenken; Paul Van Der Valk; Erwin L A Blezer; Dirk L Knol; Jonas A Castelijns; Chris H Polman; Petra J W Pouwels; Frederik Barkhof; Jeroen J G Geurts
Diffusely abnormal white matter in chronic multiple sclerosis: imaging and histopathologic analysis.
Archives of neurology 2009;66(5):601-9.
2009: Arjan Minneboo; B M J Uitdehaag; P Jongen; Hugo Vrenken; Dirk L Knol; M A A van Walderveen; C H Polman; J A Castelijns; Frederik Barkhof
Association between MRI parameters and the MS severity scale: a 12 year follow-up study.
Multiple sclerosis (Houndmills, Basingstoke, England) 2009;15(5):632-7.
2009: Dennis Chan; Valerie Anderson; Y A L Pijnenburg; Jennifer L Whitwell; Jo Barnes; Rachael I Scahill; John M Stevens; Frederik Barkhof; Philip scheltens; Martin N Rossor; Nick C Fox
The clinical profile of right temporal lobe atrophy.
Brain : a journal of neurology 2009;132(Pt 5):1287-98.
2009: Mike P Wattjes; Frederik Barkhof
High field MRI in the diagnosis of multiple sclerosis: high field-high yield?
Neuroradiology 2009;51(5):279-92.
2009: Frederik Barkhof; Massimo Filippi
MRI--the perfect surrogate marker for multiple sclerosis?
Nature reviews. Neurology 2009;5(4):182-3.
2009: Machteld M Vellinga; Hugo Vrenken; Hanneke E Hulst; Chris H Polman; Bernard M J Uitdehaag; Petra J W Pouwels; Frederik Barkhof; Jeroen J G Geurts
Use of ultrasmall superparamagnetic particles of iron oxide (USPIO)-enhanced MRI to demonstrate diffuse inflammation in the normal-appearing white matter (NAWM) of multiple sclerosis (MS) patients: an exploratory study.
Journal of magnetic resonance imaging : JMRI 2009;29(4):774-9.
2009: Salka Staekenborg; Esther L G E Koedam; Wouter J P Henneman; Pauline Stokman; Frederik Barkhof; Philip scheltens; Wiesje M van der Flier
Progression of mild cognitive impairment to dementia: contribution of cerebrovascular disease compared with medial temporal lobe atrophy.
Stroke; a journal of cerebral circulation 2009;40(4):1269-74.
2009: Tijmen Korteweg; Marco Rovaris; V Neacsu; Massimo Filippi; G Comi; B M Uitdehaag; Dirk L Knol; Chris H Polman; Frederik Barkhof; Hugo Vrenken
Can rate of brain atrophy in multiple sclerosis be explained by clinical and MRI characteristics?
Multiple sclerosis (Houndmills, Basingstoke, England) 2009;15(4):465-71.
2009: Jessica S Damoiseaux; Stephen Smith; Menno P Witter; Ernesto Sanz Arigita; Frederik Barkhof; Philip scheltens; Cornelis Stam; Mojtaba Zarei; Serge A R B Rombouts
White matter tract integrity in aging and Alzheimer's disease.
Human brain mapping 2009;30(4):1051-9.
2009: W J P Henneman; J D Sluimer; J Barnes; Wiesje M van der Flier; I C Sluimer; Nick C Fox; Philip scheltens; Hugo Vrenken; Frederik Barkhof
Hippocampal atrophy rates in Alzheimer disease: added value over whole brain volume measures.
Neurology 2009;72(11):999-1007.
2009: Mojtaba Zarei; Jeske S Damoiseaux; Ciro Morgese; Christian F Beckmann; Stephen Smith; Paul Matthews; Philip scheltens; Serge A R B Rombouts; Frederik Barkhof
Regional white matter integrity differentiates between vascular dementia and Alzheimer disease.
Stroke; a journal of cerebral circulation 2009;40(3):773-9.
2009: S D Roosendaal; Jeroen J G Geurts; Hugo Vrenken; H E Hulst; Keith S Cover; Jonas A Castelijns; Petra J W Pouwels; Frederik Barkhof
Regional DTI differences in multiple sclerosis patients.
NeuroImage 2009;44(4):1397-403.
2009: Nelleke Tolboom; Maqsood Yaqub; Wiesje M van der Flier; Ronald Boellaard; Gert Luurtsema; Albert D Windhorst; Frederik Barkhof; Philip scheltens; Adriaan A Lammertsma; Bart N M Van Berckel
Detection of Alzheimer pathology in vivo using both 11C-PIB and 18F-FDDNP PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(2):191-7.
2009: Stefan Ropele; Alexandra Seewann; Alida A Gouw; Wiesje M van der Flier; Reinhold Schmidt; Leonardo Pantoni; Domenico Inzitari; Timo Erkinjuntti; Philip scheltens; Lars-Olof Wahlund; Gunhild Waldemar; Hugues Chabriat; José Ferro; Michael Hennerici; John T O'Brien; Anders Wallin; Peter Langhorne; Marieke C Visser; Frederik Barkhof; Franz Fazekas
Quantitation of brain tissue changes associated with white matter hyperintensities by diffusion-weighted and magnetization transfer imaging: the LADIS (Leukoaraiosis and Disability in the Elderly) study.
Journal of magnetic resonance imaging : JMRI 2009;29(2):268-74.
2009: Wouter J P Henneman; Jasper D Sluimer; Charlotte Cordonnier; Merel M E Baak; Philip scheltens; Frederik Barkhof; Wiesje M van der Flier
MRI biomarkers of vascular damage and atrophy predicting mortality in a memory clinic population.
Stroke; a journal of cerebral circulation 2009;40(2):492-8.
2009: Joost C J Bot; Frederik Barkhof
Spinal-cord MRI in multiple sclerosis: conventional and nonconventional MR techniques.
Neuroimaging clinics of North America 2009;19(1):81-99.
2009: Bastiaan Moraal; Dominik Meier; Peter A Poppe; Jeroen J G Geurts; Hugo Vrenken; William M A Jonker; Dirk L Knol; Ronald A van Schijndel; Petra J W Pouwels; Christoph Pohl; Lars Bauer; Rupert Sandbrink; Charles R G Guttmann; Frederik Barkhof
Subtraction MR images in a multiple sclerosis multicenter clinical trial setting.
Radiology 2009;250(2):506-14.
2009: Domenico Inzitari; Giovanni Pracucci; Anna Poggesi; Giovanna Carlucci; Frederik Barkhof; Hugues Chabriat; Timo Erkinjuntti; Franz Fazekas; José M Ferro; Michael Hennerici; Peter Langhorne; John T O'Brien; Philip scheltens; Marieke C Visser; Lars-Olof Wahlund; Gunhild Waldemar; Anders Wallin; Leonardo Pantoni
Changes in white matter as determinant of global functional decline in older independent outpatients: three year follow-up of LADIS (leukoaraiosis and disability) study cohort.
BMJ (Clinical research ed.) 2009;339():b2477.
2009: Jessica M Nielsen; Christoph Pohl; Chris H Polman; Frederik Barkhof; Mark S Freedman; Gilles Edan; David H Miller; Lars Bauer; Rupert Sandbrink; Ludwig Kappos; Bernard M J Uitdehaag
MRI characteristics are predictive for CDMS in monofocal, but not in multifocal patients with a clinically isolated syndrome.
BMC neurology 2009;9():19.
2009: Hanna Jokinen; Hely Kalska; Raija Ylikoski; Sofia Madureira; Ana Verdelho; Wiesje M van der Flier; Philip scheltens; Frederik Barkhof; Marieke C Visser; Franz Fazekas; Reinhold Schmidt; John T O'Brien; Gunhild Waldemar; Anders Wallin; Hugues Chabriat; Leonardo Pantoni; Domenico Inzitari; Timo Erkinjuntti
Longitudinal cognitive decline in subcortical ischemic vascular disease--the LADIS Study.
Cerebrovascular diseases (Basel, Switzerland) 2009;27(4):384-91.
2009: Hanna Jokinen; Hely Kalska; Raija Ylikoski; Sofia Madureira; Ana Verdelho; Alida Gouw; Philip scheltens; Frederik Barkhof; Marieke C Visser; Franz Fazekas; Reinhold Schmidt; John T O'Brien; Michael Hennerici; Hansjorg Baezner; Gunhild Waldemar; Anders Wallin; Hugues Chabriat; Leonardo Pantoni; Domenico Inzitari; Timo Erkinjuntti
MRI-defined subcortical ischemic vascular disease: baseline clinical and neuropsychological findings. The LADIS Study.
Cerebrovascular diseases (Basel, Switzerland) 2009;27(4):336-44.
2009: Serge A R B Rombouts; Jessica S Damoiseaux; Rutger Goekoop; Frederik Barkhof; Philip scheltens; Stephen Smith; Christian F Beckmann
Model-free group analysis shows altered BOLD FMRI networks in dementia.
Human brain mapping 2009;30(1):256-66.
2008: R Jeroen Vermeulen; Petra E M Van Schie; Lotte Hendrikx; Frederik Barkhof; Mirjam van Weissenbruch; Dirk L Knol; Petra J W Pouwels
Diffusion-weighted and conventional MR imaging in neonatal hypoxic ischemia: two-year follow-up study.
Radiology 2008;249(2):631-9.
2008: Alida A Gouw; Wiesje M van der Flier; Leonardo Pantoni; Domenico Inzitari; Timo Erkinjuntti; Lars-Olof Wahlund; Gunhild Waldemar; Reinhold Schmidt; Franz Fazekas; Philip scheltens; Frederik Barkhof
On the etiology of incident brain lacunes: longitudinal observations from the LADIS study.
Stroke; a journal of cerebral circulation 2008;39(11):3083-5.
2008: Salka Staekenborg; E C W van Straaten; Wiesje M van der Flier; R Lane; Frederik Barkhof; Philip scheltens
Small vessel versus large vessel vascular dementia: risk factors and MRI findings.
Journal of neurology 2008;255(11):1644-51; discussion 1813-4.
2008: Daniel D Mikol; Frederik Barkhof; Peter Chang; Patricia K Coyle; Douglas R Jeffery; Steven R Schwid; Bettina Stubinski; Bernard Uitdehaag
Comparison of subcutaneous interferon beta-1a with glatiramer acetate in patients with relapsing multiple sclerosis (the REbif vs Glatiramer Acetate in Relapsing MS Disease [REGARD] study): a multicentre, randomised, parallel, open-label trial.
Lancet neurology 2008;7(10):903-14.
2008: Rogier C J de Jonge; Joost F Swart; Irene Koomen; Serge A R B Rombouts; Reinoud J B J Gemke; Frederik Barkhof; A Marceline van Furth
No structural cerebral differences between children with a history of bacterial meningitis and healthy siblings.
Acta paediatrica (Oslo, Norway : 1992) 2008;97(10):1390-6.
2008: Bastiaan Moraal; Stefan D Roosendaal; Petra J W Pouwels; Hugo Vrenken; Ronald A van Schijndel; Dominik Meier; Charles R G Guttmann; Jeroen J G Geurts; Frederik Barkhof
Multi-contrast, isotropic, single-slab 3D MR imaging in multiple sclerosis.
European radiology 2008;18(10):2311-20.
2008: Veronica Neacsu; jasperse bas; Tijmen Korteweg; Dirk L Knol; Paola Valsasina; Massimo Filippi; Frederik Barkhof; Marco Rovaris; Hugo Vrenken
Agreement between different input image types in brain atrophy measurement in multiple sclerosis using SIENAX and SIENA.
Journal of magnetic resonance imaging : JMRI 2008;28(3):559-65.
2008: Jeroen J G Geurts; Frederik Barkhof
Grey matter pathology in multiple sclerosis.
Lancet neurology 2008;7(9):841-51.
2008: R Bosnell; C Wegner; Zsigmond Tamas Kincses; Tijmen Korteweg; Federica Agosta; Olga Ciccarelli; Nicola de Stefano; A Gass; J Hirsch; Heidi Johansen-Berg; L Kappos; Frederik Barkhof; L Mancini; F Manfredonia; S Marino; David H Miller; Xavier Montalban; Jacqueline Palace; M Rocca; Christian Enzinger; Stefan Ropele; A Rovira; Stephen Smith; A Thompson; J Thornton; T Yousry; B Whitcher; Massimo Filippi; Paul Matthews
Reproducibility of fMRI in the clinical setting: implications for trial designs.
NeuroImage 2008;42(2):603-10.
2008: Jasper D Sluimer; Wiesje M van der Flier; Giorgos Karas; Nick C Fox; Philip scheltens; Frederik Barkhof; Hugo Vrenken
Whole-brain atrophy rate and cognitive decline: longitudinal MR study of memory clinic patients.
Radiology 2008;248(2):590-8.
2008: António J Bastos Leite; J P A Kuijer; Serge A R B Rombouts; Ernesto Sanz Arigita; E C van Straaten; Alida A Gouw; W M van der Flier; Philip scheltens; Frederik Barkhof
Cerebral blood flow by using pulsed arterial spin-labeling in elderly subjects with white matter hyperintensities.
AJNR. American journal of neuroradiology 2008;29(7):1296-301.
2008: Arjan Minneboo; jasperse bas; Frederik Barkhof; Bernard Uitdehaag; Dirk L Knol; Vincent de Groot; Chris H Polman; Jonas A Castelijns
Predicting short-term disability progression in early multiple sclerosis: added value of MRI parameters.
Journal of neurology, neurosurgery, and psychiatry 2008;79(8):917-23.
2008: Giovanni B Frisoni; Wouter J P Henneman; Michael Weiner; Philip scheltens; Bruno Vellas; Emma Reynish; Jaroslava Hudecova; Harald Hampel; Katharina Burger; Kaj Blennow; Gunhild Waldemar; Peter Johannsen; Lars-Olof Wahlund; Giancarlo Zito; Paolo M Rossini; Bengt Winblad; Frederik Barkhof
The pilot European Alzheimer's Disease Neuroimaging Initiative of the European Alzheimer's Disease Consortium.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2008;4(4):255-64.
2008: I J van den Elskamp; J Lembcke; V Dattola; Karola Beckmann; Christoph Pohl; W Hong; Rupert Sandbrink; Klaus Wagner; D L Knol; Bernard Uitdehaag; Frederik Barkhof
Persistent T1 hypointensity as an MRI marker for treatment efficacy in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2008;14(6):764-9.
2008: Rohit Bakshi; Alan J Thompson; Maria A Rocca; Daniel Pelletier; Vincent Dousset; Frederik Barkhof; Matilde Inglese; Charles R G Guttmann; Mark A Horsfield; Massimo Filippi
MRI in multiple sclerosis: current status and future prospects.
Lancet neurology 2008;7(7):615-25.
2008: Tim B Dyrby; Egill Rostrup; William F C Baaré; Elisabeth C W van Straaten; Frederik Barkhof; Hugo Vrenken; Stefan Ropele; Reinhold Schmidt; Timo Erkinjuntti; Lars-Olof Wahlund; Leonardo Pantoni; Domenico Inzitari; Olaf B Paulson; Lars Kai Hansen; Gunhild Waldemar
Segmentation of age-related white matter changes in a clinical multi-center study.
NeuroImage 2008;41(2):335-45.
2008: Zhaleh Khaleeli; Olga Ciccarelli; Francesco Manfredonia; Frederik Barkhof; B Brochet; Mara Cercignani; V Dousset; Massimo Filippi; Xavier Montalban; Chris Polman; Marco Rovaris; Alex Rovira; Jaume Sastre-Garriga; Machteld Vellinga; David Miller; Alan Thompson
Predicting progression in primary progressive multiple sclerosis: a 10-year multicenter study.
Annals of neurology 2008;63(6):790-3.
2008: J D Sluimer; Hugo Vrenken; Marinus A Blankenstein; Nick C Fox; Philip scheltens; Frederik Barkhof; Wiesje M van der Flier
Whole-brain atrophy rate in Alzheimer disease: identifying fast progressors.
Neurology 2008;70(19 Pt 2):1836-41.
2008: Alette M Wessels; Philip scheltens; Frederik Barkhof; Robert J Heine
Hyperglycaemia as a determinant of cognitive decline in patients with type 1 diabetes.
European journal of pharmacology 2008;585(1):88-96.
2008: Alida A Gouw; Wiesje M van der Flier; Franz Fazekas; E C W van Straaten; Leonardo Pantoni; Anna Poggesi; Domenico Inzitari; Timo Erkinjuntti; Lars-Olof Wahlund; Gunhild Waldemar; Reinhold Schmidt; Philip scheltens; Frederik Barkhof
Progression of white matter hyperintensities and incidence of new lacunes over a 3-year period: the Leukoaraiosis and Disability study.
Stroke; a journal of cerebral circulation 2008;39(5):1414-20.
2008: Giorgos Karas; J Sluimer; Rutger Goekoop; Wiesje M van der Flier; Serge A R B Rombouts; Hugo Vrenken; Philip scheltens; Nick C Fox; Frederik Barkhof
Amnestic mild cognitive impairment: structural MR imaging findings predictive of conversion to Alzheimer disease.
AJNR. American journal of neuroradiology 2008;29(5):944-9.
2008: O W M Meijer; E J Weijmans; Dirk L Knol; Ben Slotman; Frederik Barkhof; W Peter Vandertop; Jonas A Castelijns
Tumor-volume changes after radiosurgery for vestibular schwannoma: implications for follow-up MR imaging protocol.
AJNR. American journal of neuroradiology 2008;29(5):906-10.
2008: Marco Rovaris; Elda Judica; Jaume Sastre-Garriga; Alex Rovira; Maria Pia Sormani; Beatrice Benedetti; Tijmen Korteweg; Nicola de Stefano; Zhaleh Khaleeli; Xavier Montalban; Frederik Barkhof; David H Miller; Chris Polman; Alan J Thompson; Massimo Filippi
Large-scale, multicentre, quantitative MRI study of brain and cord damage in primary progressive multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2008;14(4):455-64.
2008: Niki S M Schoonenboom; Wiesje M van der Flier; Marinus A Blankenstein; Femke H Bouwman; Gerard J van Kamp; Frederik Barkhof; Philip scheltens
CSF and MRI markers independently contribute to the diagnosis of Alzheimer's disease.
Neurobiology of aging 2008;29(5):669-75.
2008: Stefan D Roosendaal; Bastiaan Moraal; Hugo Vrenken; Jonas A Castelijns; Petra J W Pouwels; Frederik Barkhof; Jeroen J G Geurts
In vivo MR imaging of hippocampal lesions in multiple sclerosis.
Journal of magnetic resonance imaging : JMRI 2008;27(4):726-31.
2008: J N P Zwemmer; Joost C J Bot; Brechtje Jelles; Frederik Barkhof; Chris H Polman
At the heart of primary progressive multiple sclerosis: three cases with diffuse MRI abnormalities only.
Multiple sclerosis (Houndmills, Basingstoke, England) 2008;14(3):428-30.
2008: Salka S Staekenborg; Freek Gillissen; Rolinka Romkes; Y A L Pijnenburg; Frederik Barkhof; Philip scheltens; Wiesje M van der Flier
Behavioural and psychological symptoms are not related to white matter hyperintensities and medial temporal lobe atrophy in Alzheimer's disease.
International journal of geriatric psychiatry 2008;23(4):387-92.
2008: Chris H Polman; S C Reingold; Frederik Barkhof; Peter A Calabresi; M Clanet; J A Cohen; Gary R Cutter; M S Freedman; Ludwig Kappos; F D Lublin; Henry McFarland; L M Metz; A E Miller; X Montalban; P W O'Connor; Hillel Panitch; J R Richert; J Petkau; S R Schwid; M P Sormani; A J Thompson; B G Weinshenker; Jerry Wolinsky
Ethics of placebo-controlled clinical trials in multiple sclerosis: a reassessment.
Neurology 2008;70(13 Pt 2):1134-40.
2008: M M Vellinga; Jonas A Castelijns; Frederik Barkhof; Bernard Uitdehaag; Chris H Polman
Postwithdrawal rebound increase in T2 lesional activity in natalizumab-treated MS patients.
Neurology 2008;70(13 Pt 2):1150-1.
2008: Machteld M Vellinga; Raoul D Oude Engberink; Alexandra Seewann; Petra J W Pouwels; Mike P Wattjes; Susanne M A van der Pol; Christiane Pering; Chris H Polman; Helga E de Vries; Jeroen J G Geurts; Frederik Barkhof
Pluriformity of inflammation in multiple sclerosis shown by ultra-small iron oxide particle enhancement.
Brain : a journal of neurology 2008;131(Pt 3):800-7.
2008: Y Duan; P G Hildenbrand; M P Sampat; David F Tate; I Csapo; B Moraal; R Bakshi; Frederik Barkhof; Dominik Meier; Charles R G Guttmann
Segmentation of subtraction images for the measurement of lesion change in multiple sclerosis.
AJNR. American journal of neuroradiology 2008;29(2):340-6.
2008: Jeroen J G Geurts; Erwin L A Blezer; Hugo Vrenken; Annette van der Toorn; Jonas A Castelijns; Chris H Polman; Petra J W Pouwels; Lars Bö; Frederik Barkhof
Does high-field MR imaging improve cortical lesion detection in multiple sclerosis?
Journal of neurology 2008;255(2):183-91.
2008: Salka Staekenborg; Wiesje M van der Flier; E C W van Straaten; Roger Lane; Frederik Barkhof; Philip scheltens
Neurological signs in relation to type of cerebrovascular disease in vascular dementia.
Stroke; a journal of cerebral circulation 2008;39(2):317-22.
2008: Giorgos Karas; Philip scheltens; Frederik Barkhof
Feature extraction and strategy of analyzing structural neuroimaging in dementia.
Handbook of clinical neurology 2008;89():75-86.
2008: A A Gouw; W M van der Flier; E C W van Straaten; Leonardo Pantoni; António J Bastos Leite; Domenico Inzitari; Timo Erkinjuntti; Lars-Olof Wahlund; C Ryberg; Reinhold Schmidt; Franz Fazekas; Philip scheltens; Frederik Barkhof
Reliability and sensitivity of visual scales versus volumetry for evaluating white matter hyperintensity progression.
Cerebrovascular diseases (Basel, Switzerland) 2008;25(3):247-53.
2008: A Seewann; Christian Enzinger; Massimo Filippi; Frederik Barkhof; A Rovira; A Gass; D Miller; X Montalban; A Thompson; T Yousry; M Tintore; N de Stefano; J Palace; M Rovaris; C Polman; Franz Fazekas
MRI characteristics of atypical idiopathic inflammatory demyelinating lesions of the brain : A review of reported findings.
Journal of neurology 2008;255(1):1-10.
2007: António J Bastos Leite; Wiesje M van der Flier; E C W van Straaten; Salka Staekenborg; Philip scheltens; Frederik Barkhof
The contribution of medial temporal lobe atrophy and vascular pathology to cognitive impairment in vascular dementia.
Stroke; a journal of cerebral circulation 2007;38(12):3182-5.
2007: Giorgos Karas; Philip scheltens; Serge A R B Rombouts; Ronald A van Schijndel; Martin Klein; Bethany Jones; Wiesje M van der Flier; Hugo Vrenken; Frederik Barkhof
Precuneus atrophy in early-onset Alzheimer's disease: a morphometric structural MRI study.
Neuroradiology 2007;49(12):967-76.
2007: Serge A R B Rombouts; Philip scheltens; Joost P A Kuijer; Frederik Barkhof
Whole brain analysis of T2* weighted baseline FMRI signal in dementia.
Human brain mapping 2007;28(12):1313-7.
2007: jasperse bas; Hugo Vrenken; Ernesto Sanz Arigita; Vincent de Groot; Stephen Smith; Chris H Polman; Frederik Barkhof
Regional brain atrophy development is related to specific aspects of clinical dysfunction in multiple sclerosis.
NeuroImage 2007;38(3):529-37.
2007: Frederik Barkhof; Tuomo Polvikoski; E C W van Straaten; Rajesh N. Kalaria; Raimo Sulkava; H J Aronen; Leena Niinistö; Sari Rastas; M Oinas; Philip scheltens; Timo Erkinjuntti
The significance of medial temporal lobe atrophy: a postmortem MRI study in the very old.
Neurology 2007;69(15):1521-7.
2007: Laura A van de Pol; Wiesje M van der Flier; Esther S C Korf; Nick C Fox; Frederik Barkhof; Philip scheltens
Baseline predictors of rates of hippocampal atrophy in mild cognitive impairment.
Neurology 2007;69(15):1491-7.
2007: jasperse bas; Paola Valsasina; Veronica Neacsu; Dirk L Knol; Nicola De Stefano; Christian Enzinger; Stephen Smith; Stefan Ropele; Tijmen Korteweg; Antonio Giorgio; Valerie Anderson; Chris H Polman; Massimo Filippi; David H Miller; Marco Rovaris; Frederik Barkhof; Hugo Vrenken
Intercenter agreement of brain atrophy measurement in multiple sclerosis patients using manually-edited SIENA and SIENAX.
Journal of magnetic resonance imaging : JMRI 2007;26(4):881-5.
2007: Rogier E Hagenbeek; Serge A R B Rombouts; Dick J Veltman; Jan Van Strien; Menno P Witter; Philip scheltens; Frederik Barkhof
Nonlinear changes in brain activity during continuous word repetition: an event-related multiparametric functional MR imaging study.
AJNR. American journal of neuroradiology 2007;28(9):1715-21.
2007: Tineke Van Veen; Jessica Nielsen; Johannes Berkhof; Frederik Barkhof; Wouter Kamphorst; Lars Bö; Rivka Ravid; Cornelis L Verweij; Inge Huitinga; Chris H Polman; Bernard Uitdehaag
CCL5 and CCR5 genotypes modify clinical, radiological and pathological features of multiple sclerosis.
Journal of neuroimmunology 2007;190(1-2):157-64.
2007: M Liedorp; E Sanchez; I M W van Hoogstraten; B Mary E von Blomberg; Frederik Barkhof; Chris H Polman; Joep Killestein
No evidence of misdiagnosis in patients with multiple sclerosis and repeated positive anticardiolipin antibody testing based on magnetic resonance imaging and long term follow-up.
Journal of neurology, neurosurgery, and psychiatry 2007;78(10):1146-8.
2007: Frederik Barkhof; Chris H Polman; Ernst-Wilhelm Radue; Ludwig Kappos; Mark S Freedman; Gilles Edan; Hans-Peter Hartung; David H Miller; Xavier Montalbán; Peter A Poppe; Marlieke de Vos; Fatiha Lasri; Lars Bauer; Susanne Dahms; Klaus Wagner; Christoph Pohl; Rupert Sandbrink
Magnetic resonance imaging effects of interferon beta-1b in the BENEFIT study: integrated 2-year results.
Archives of neurology 2007;64(9):1292-8.
2007: Jeroen J G Geurts; Lars Bö; Stefan D Roosendaal; Thierry Hazes; Richard Daniëls; Frederik Barkhof; Menno P Witter; Inge Huitinga; Paul Van Der Valk
Extensive hippocampal demyelination in multiple sclerosis.
Journal of neuropathology and experimental neurology 2007;66(9):819-27.
2007: Ludwig Kappos; Mark S Freedman; Chris H Polman; Gilles Edan; Hans-Peter Hartung; David H Miller; Xavier Montalbán; Frederik Barkhof; Ernst W Radü; Lars Bauer; Susanne Dahms; Vivian Lanius; Christoph Pohl; Rupert Sandbrink
Effect of early versus delayed interferon beta-1b treatment on disability after a first clinical event suggestive of multiple sclerosis: a 3-year follow-up analysis of the BENEFIT study.
Lancet 2007;370(9585):389-97.
2007: Josephine K Swanton; Alex Rovira; Mar Tintore; Daniel R Altmann; Frederik Barkhof; Massimo Filippi; Elena Huerga; Katherine A Miszkiel; Gordon T Plant; Chris H Polman; Marco Rovaris; Alan J Thompson; Xavier Montalban; David H Miller
MRI criteria for multiple sclerosis in patients presenting with clinically isolated syndromes: a multicentre retrospective study.
Lancet neurology 2007;6(8):677-86.
2007: Alette M Wessels; Serge A R B Rombouts; Peter L Remijnse; Y Boom; Philip scheltens; Frederik Barkhof; Robert J Heine; Frank J Snoek
Cognitive performance in type 1 diabetes patients is associated with cerebral white matter volume.
Diabetologia 2007;50(8):1763-9.
2007: Laura A van de Pol; Esther S C Korf; Wiesje M van der Flier; H Robert Brashear; Nick C Fox; Frederik Barkhof; Philip scheltens
Magnetic resonance imaging predictors of cognition in mild cognitive impairment.
Archives of neurology 2007;64(7):1023-8.
2007: Jessica M Nielsen; B Moraal; Chris H Polman; Peter A Poppe; M de Vos; Mark S Freedman; Ludwig Kappos; Frederik Barkhof; Lars Bauer; Christoph Pohl; Rupert Sandbrink; Hans-Peter Hartung; Bernard Uitdehaag
Classification of patients with a clinically isolated syndrome based on signs and symptoms is supported by magnetic resonance imaging results.
Multiple sclerosis (Houndmills, Basingstoke, England) 2007;13(6):717-21.
2007: Hugo Vrenken; Petra J W Pouwels; Stefan Ropele; Dirk L Knol; Jeroen J G Geurts; Chris H Polman; Frederik Barkhof; Jonas A Castelijns
Magnetization transfer ratio measurement in multiple sclerosis normal-appearing brain tissue: limited differences with controls but relationships with clinical and MR measures of disease.
Multiple sclerosis (Houndmills, Basingstoke, England) 2007;13(6):708-16.
2007: Femke H Bouwman; S N M Schoonenboom; Wiesje M van der Flier; Evert-Jan van Elk; astrid kok; Frederik Barkhof; Marinus A Blankenstein; Philip scheltens
CSF biomarkers and medial temporal lobe atrophy predict dementia in mild cognitive impairment.
Neurobiology of aging 2007;28(7):1070-4.
2007: Cees Mulder; Wiesje M van der Flier; Robert Veerhuis; Femke H Bouwman; Cornelis Jakobs; Nanda M Verhoeven; Frederik Barkhof; Philip scheltens; Marinus A Blankenstein
Association between vitamin B6 and white matter hyperintensities in patients with Alzheimer's disease not mediated by homocysteine metabolism.
Journal of the American Geriatrics Society 2007;55(6):956-8.
2007: Nynke F Kalkers; Rob L M Strijers; M M S Jasperse; V Neacsu; Jeroen J G Geurts; Frederik Barkhof; Chris H Polman; Cornelis Stam
Motor evoked potential: a reliable and objective measure to document the functional consequences of multiple sclerosis? Relation to disability and MRI.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2007;118(6):1332-40.
2007: Charlotte Ryberg; Egill Rostrup; M B Stegmann; Frederik Barkhof; Philip scheltens; E C W van Straaten; Franz Fazekas; Reinhold Schmidt; José M Ferro; Hansjoerg Baezner; Timo Erkinjuntti; Hanna Jokinen; Lars-Olof Wahlund; John T O'Brien; Anna Maria Basile; Leonardo Pantoni; Domenico Inzitari; Gunhild Waldemar
Clinical significance of corpus callosum atrophy in a mixed elderly population.
Neurobiology of aging 2007;28(6):955-63.
2007: jasperse bas; Cornelis Jakobs; M Judith Eikelenboom; Christine D Dijkstra; Bernard Uitdehaag; Frederik Barkhof; Chris H Polman; Charlotte E Teunissen
N-acetylaspartic acid in cerebrospinal fluid of multiple sclerosis patients determined by gas-chromatography-mass spectrometry.
Journal of neurology 2007;254(5):631-7.
2007: Lisa van Winsen; Tineke Van Veen; Elisabeth F C van Rossum; Jan W Koper; Frederik Barkhof; Chris H Polman; Bernard Uitdehaag
Glucocorticoid receptor gene polymorphisms associated with more aggressive disease phenotype in MS.
Journal of neuroimmunology 2007;186(1-2):150-5.
2007: Franca A Gerards; Jos W R Twisk; M Bakker; Frederik Barkhof; John M G van Vugt
Fetal lung volume: three-dimensional ultrasonography compared with magnetic resonance imaging.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2007;29(5):533-6.
2007: Hanna Jokinen; Charlotte Ryberg; Hely Kalska; Raija Ylikoski; Egill Rostrup; Mikkel B Stegmann; Gunhild Waldemar; Sofia Madureira; José M Ferro; E C W van Straaten; Philip scheltens; Frederik Barkhof; Franz Fazekas; Reinhold Schmidt; Giovanna Carlucci; Leonardo Pantoni; Domenico Inzitari; Timo Erkinjuntti
Corpus callosum atrophy is associated with mental slowing and executive deficits in subjects with age-related white matter hyperintensities: the LADIS Study.
Journal of neurology, neurosurgery, and psychiatry 2007;78(5):491-6.
2007: Petra E M Van Schie; Jules G Becher; Annet J Dallmeijer; Frederik Barkhof; M M Weissenbruch; R Jeroen Vermeulen
Motor outcome at the age of one after perinatal hypoxic-ischemic encephalopathy.
Neuropediatrics 2007;38(2):71-7.
2007: Wiesje M van der Flier; Frederik Barkhof; Philip scheltens
Shifting paradigms in dementia: toward stratification of diagnosis and treatment using MRI.
Annals of the New York Academy of Sciences 2007;1097():215-24.
2007: jasperse bas; Arjan Minneboo; Vincent de Groot; Nynke F Kalkers; Paul E van Helden; Bernard Uitdehaag; Frederik Barkhof; Chris H Polman
Determinants of cerebral atrophy rate at the time of diagnosis of multiple sclerosis.
Archives of neurology 2007;64(2):190-4.
2007: Esther S C Korf; E C W van Straaten; Frank-Erik De Leeuw; Wiesje M van der Flier; Frederik Barkhof; Leonardo Pantoni; Anna Maria Basile; Domenico Inzitari; Timo Erkinjuntti; Lars-Olof Wahlund; Egill Rostrup; R Schmidt; Franz Fazekas; Philip scheltens
Diabetes mellitus, hypertension and medial temporal lobe atrophy: the LADIS study.
Diabetic medicine : a journal of the British Diabetic Association 2007;24(2):166-71.
2007: Laura A van de Pol; Josephine Barnes; Rachael I Scahill; Chris Frost; Emma B Lewis; Richard Boyes; Ronald A van Schijndel; Philip scheltens; Nick C Fox; Frederik Barkhof
Improved reliability of hippocampal atrophy rate measurement in mild cognitive impairment using fluid registration.
NeuroImage 2007;34(3):1036-41.
2007: Jens Kuhle; Christoph Pohl; Matthias Mehling; Gilles Edan; Mark S Freedman; Hans-Peter Hartung; Chris H Polman; David H Miller; Xavier Montalban; Frederik Barkhof; Lars Bauer; Susanne Dahms; Raija L P Lindberg; Ludwig Kappos; Rupert Sandbrink
Lack of association between antimyelin antibodies and progression to multiple sclerosis.
The New England journal of medicine 2007;356(4):371-8.
2007: Domenico Inzitari; Michela Simoni; Giovanni Pracucci; Anna Poggesi; Anna Maria Basile; Hugues Chabriat; Timo Erkinjuntti; Franz Fazekas; José M Ferro; Michael Hennerici; Peter Langhorne; John T O'Brien; Frederik Barkhof; Marieke C Visser; Lars-Olof Wahlund; Gunhild Waldemar; Anders Wallin; Leonardo Pantoni
Risk of rapid global functional decline in elderly patients with severe cerebral age-related white matter changes: the LADIS study.
Archives of internal medicine 2007;167(1):81-8.
2007: P J H Jongen; Geert Lycklama a Nijeholt; Karel J B Lamers; Wim H Doesburg; Frederik Barkhof; Wim A J G Lemmens; Ina S Klasen; Otto R Hommes
Cerebrospinal fluid IgM index correlates with cranial MRI lesion load in patients with multiple sclerosis.
European neurology 2007;58(2):90-5.
2007: Raija Ylikoski; Hanna Jokinen; Pia Andersen; Oili Salonen; Sofia Madureira; Jose Ferro; Frederik Barkhof; Wiesje M van der Flier; Reinhold Schmidt; Franz Fazekas; Philip scheltens; Gunhild Waldemar; Emilia Salvadori; Leonardo Pantoni; Domenico Inzitari; Timo Erkinjuntti
Comparison of the Alzheimer's Disease Assessment Scale Cognitive Subscale and the Vascular Dementia Assessment Scale in differentiating elderly individuals with different degrees of white matter changes. The LADIS Study.
Dementia and geriatric cognitive disorders 2007;24(2):73-81.
2007: Lars Bö; Jeroen J G Geurts; Paul Van Der Valk; Chris H Polman; Frederik Barkhof
Lack of correlation between cortical demyelination and white matter pathologic changes in multiple sclerosis.
Archives of neurology 2007;64(1):76-80.
2007: Dennis R Buis; Frank J Lagerwaard; Clemens M F Dirven; Frederik Barkhof; Dirk L Knol; René van den Berg; Ben Slotman; W Peter Vandertop
Delineation of brain AVMs on MR-Angiography for the purpose of stereotactic radiosurgery.
International journal of radiation oncology, biology, physics 2007;67(1):308-16.
2007: Anda H van Stegeren; Oliver T Wolf; Walter Everaerd; Philip scheltens; Frederik Barkhof; Serge A R B Rombouts
Endogenous cortisol level interacts with noradrenergic activation in the human amygdala.
Neurobiology of learning and memory 2007;87(1):57-66.
2007: Tijmen Korteweg; Bernard Uitdehaag; Dirk L Knol; Robin H M Smithuis; Paul R Algra; Cees de Vries; Peter A Poppe; Jan-Hein T M van Waesberghe; Elisabeth Bergers; Geert Lycklama à Nijeholt; Chris H Polman; Frederik Barkhof
Interobserver agreement on the radiological criteria of the International Panel on the diagnosis of multiple sclerosis.
European radiology 2007;17(1):67-71.
2006: R H C Lazeron; Leo De Sonneville; Philip scheltens; Chris H Polman; Frederik Barkhof
Cognitive slowing in multiple sclerosis is strongly associated with brain volume reduction.
Multiple sclerosis (Houndmills, Basingstoke, England) 2006;12(6):760-8.
2006: Petra J W Pouwels; Joost P A Kuijer; John P Mugler; Charles R G Guttmann; Frederik Barkhof
Human gray matter: feasibility of single-slab 3D double inversion-recovery high-spatial-resolution MR imaging.
Radiology 2006;241(3):873-9.
2006: António J Bastos Leite; Jan-Hein T M van Waesberghe; Ayke L Oen; Wiesje M van der Flier; Philip scheltens; Frederik Barkhof
Hippocampal sulcus width and cavities: comparison between patients with Alzheimer disease and nondemented elderly subjects.
AJNR. American journal of neuroradiology 2006;27(10):2141-5.
2006: J Patrick van der Voorn; Petra J W Pouwels; Augustinus A M Hart; Judith Serrarens; Michèl A A P Willemsen; H P H Kremer; Frederik Barkhof; Marjo S van der Knaap
Childhood white matter disorders: quantitative MR imaging and spectroscopy.
Radiology 2006;241(2):510-7.
2006: Ludwig Kappos; Chris H Polman; Mark S Freedman; Gilles Edan; H P Hartung; David H Miller; Xavier Montalban; Frederik Barkhof; L Bauer; Peter Jakobs; C Pohl; Rupert Sandbrink
Treatment with interferon beta-1b delays conversion to clinically definite and McDonald MS in patients with clinically isolated syndromes.
Neurology 2006;67(7):1242-9.
2006: J N P Zwemmer; J Berkhof; Jonas A Castelijns; Frederik Barkhof; Chris H Polman; Bernard Uitdehaag
Classification of multiple sclerosis patients by latent class analysis of magnetic resonance imaging characteristics.
Multiple sclerosis (Houndmills, Basingstoke, England) 2006;12(5):565-72.
2006: Hugo Vrenken; Jeroen J G Geurts; Dirk L Knol; Chris H Polman; Jonas A Castelijns; Petra J W Pouwels; Frederik Barkhof
Normal-appearing white matter changes vary with distance to lesions in multiple sclerosis.
AJNR. American journal of neuroradiology 2006;27(9):2005-11.
2006: Arnaud Charil; Tarek A Yousry; Marco Rovaris; Frederik Barkhof; Nicola de Stefano; Franz Fazekas; David H Miller; Xavier Montalban; Jack H Simon; Chris H Polman; Massimo Filippi
MRI and the diagnosis of multiple sclerosis: expanding the concept of "no better explanation".
Lancet neurology 2006;5(10):841-52.
2006: Alette M Wessels; Suat Simsek; Peter L Remijnse; Dick J Veltman; Geert Jan Biessels; Frederik Barkhof; Philip scheltens; Frank J Snoek; Robert J Heine; Serge A R B Rombouts
Voxel-based morphometry demonstrates reduced grey matter density on brain MRI in patients with diabetic retinopathy.
Diabetologia 2006;49(10):2474-80.
2006: Alida A Gouw; Wiesje M van der Flier; E C W van Straaten; Frederik Barkhof; José M Ferro; Hansjoerg Baezner; Leonardo Pantoni; Domenico Inzitari; Timo Erkinjuntti; Lars-Olof Wahlund; Gunhild Waldemar; Reinhold Schmidt; Franz Fazekas; Philip scheltens
Simple versus complex assessment of white matter hyperintensities in relation to physical performance and cognition: the LADIS study.
Journal of neurology 2006;253(9):1189-96.
2006: Frank-Erik De Leeuw; Esther Korf; Frederik Barkhof; Philip scheltens
White matter lesions are associated with progression of medial temporal lobe atrophy in Alzheimer disease.
Stroke; a journal of cerebral circulation 2006;37(9):2248-52.
2006: Hugo Vrenken; Jeroen J G Geurts; Dirk L Knol; L Noor van Dijk; Vincenzo Dattola; jasperse bas; Ronald A van Schijndel; Chris H Polman; Jonas A Castelijns; Frederik Barkhof; Petra J W Pouwels
Whole-brain T1 mapping in multiple sclerosis: global changes of normal-appearing gray and white matter.
Radiology 2006;240(3):811-20.
2006: Ying Wu; Simon K Warfield; I Leng Tan; William M Wells; Dominik Meier; Ronald A van Schijndel; Frederik Barkhof; Charles R G Guttmann
Automated segmentation of multiple sclerosis lesion subtypes with multichannel MRI.
NeuroImage 2006;32(3):1205-15.
2006: Leonardo Pantoni; Anna Poggesi; Anna Maria Basile; Giovanni Pracucci; Frederik Barkhof; Hugues Chabriat; Timo Erkinjuntti; José M Ferro; Michael Hennerici; John T O'Brien; Reinhold Schmidt; Marieke C Visser; Lars-Olof Wahlund; Gunhild Waldemar; Anders Wallin; Domenico Inzitari
Leukoaraiosis predicts hidden global functioning impairment in nondisabled older people: the LADIS (Leukoaraiosis and Disability in the Elderly) Study.
Journal of the American Geriatrics Society 2006;54(7):1095-101.
2006: Rutger Goekoop; Frederik Barkhof; Erik J J Duschek; JAN COEN NETELENBOS; Dirk L Knol; Philip scheltens; Serge A R B Rombouts
Raloxifene treatment enhances brain activation during recognition of familiar items: a pharmacological fMRI study in healthy elderly males.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(7):1508-18.
2006: Charlotte E Teunissen; Christine D Dijkstra; jasperse bas; Frederik Barkhof; hugo vanderstichele; Eugeen Vanmechelen; Chris H Polman; Lars Bö
Growth-associated protein 43 in lesions and cerebrospinal fluid in multiple sclerosis.
Neuropathology and applied neurobiology 2006;32(3):318-31.
2006: David K B Li; Ulrike Held; John Petkau; Martin Daumer; Frederik Barkhof; Franz Fazekas; J A Frank; Ludwig Kappos; David H Miller; JH Simon; Jerry Wolinsky; Massimo Filippi
MRI T2 lesion burden in multiple sclerosis: a plateauing relationship with clinical disability.
Neurology 2006;66(9):1384-9.
2006: C Cordonnier; Wiesje M van der Flier; J D Sluimer; Didier LEYS; Frederik Barkhof; Philip scheltens
Prevalence and severity of microbleeds in a memory clinic setting.
Neurology 2006;66(9):1356-60.
2006: Jessica M Nielsen; Frederik Barkhof; Bob W van Oosten; Chris H Polman
The role of spinal cord imaging in the diagnosis of multiple sclerosis.
Nature clinical practice. Neurology 2006;2(5):283-6; quiz 287.
2006: Hugo Vrenken; Petra J W Pouwels; Jeroen J G Geurts; Dirk L Knol; Chris H Polman; Frederik Barkhof; Jonas A Castelijns
Altered diffusion tensor in multiple sclerosis normal-appearing brain tissue: cortical diffusion changes seem related to clinical deterioration.
Journal of magnetic resonance imaging : JMRI 2006;23(5):628-36.
2006: Hugo Vrenken; Serge A R B Rombouts; Petra J W Pouwels; Frederik Barkhof
Voxel-based analysis of quantitative T1 maps demonstrates that multiple sclerosis acts throughout the normal-appearing white matter.
AJNR. American journal of neuroradiology 2006;27(4):868-74.
2006: Laura A van de Pol; Anke Hensel; Wiesje M van der Flier; Pieter Jelle Visser; Y A L Pijnenburg; Frederik Barkhof; Hermann-Josef Gertz; Philip scheltens
Hippocampal atrophy on MRI in frontotemporal lobar degeneration and Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 2006;77(4):439-42.
2006: Tarek A Yousry; Eugene O Major; Caroline Ryschkewitsch; Gary Fahle; Steven Fischer; Jean Hou; Blanche Curfman; Katherine A Miszkiel; Nicole Mueller-Lenke; Esther Sanchez; Frederik Barkhof; Ernst-Wilhelm Radue; Hans R Jäger; David B Clifford
Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy.
The New England journal of medicine 2006;354(9):924-33.
2006: Marjo S van der Knaap; Marjolein Kriek; W C G Overweg-Plandsoen; K B M Hansson; Kamlesh Madan; J S Starreveld; P Schotman-Schram; Frederik Barkhof; Saskia A J Lesnik Oberstein
Cerebral white matter abnormalities in 6p25 deletion syndrome.
AJNR. American journal of neuroradiology 2006;27(3):586-8.
2006: Tijmen Korteweg; Mar Tintoré; Bernard Uitdehaag; Alex Rovira; Jette Frederiksen; David Miller; Kryshani T M Fernando; Massimo Filippi; Federica Agosta; Maria Rocca; Franz Fazekas; Christian Enzinger; Paul Matthews; Allyson Parry; Chris H Polman; Xavier Montalban; Frederik Barkhof
MRI criteria for dissemination in space in patients with clinically isolated syndromes: a multicentre follow-up study.
Lancet neurology 2006;5(3):221-7.
2006: Geert Jan Biessels; Frank-Erik De Leeuw; Jaap Lindeboom; Frederik Barkhof; Philip scheltens
Increased cortical atrophy in patients with Alzheimer's disease and type 2 diabetes mellitus.
Journal of neurology, neurosurgery, and psychiatry 2006;77(3):304-7.
2006: Jeroen J G Geurts; Ilona E W Reuling; Hugo Vrenken; Bernard Uitdehaag; Chris H Polman; Jonas A Castelijns; Frederik Barkhof; Petra J W Pouwels
MR spectroscopic evidence for thalamic and hippocampal, but not cortical, damage in multiple sclerosis.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;55(3):478-83.
2006: E C W van Straaten; Franz Fazekas; Egill Rostrup; Philip scheltens; Reinhold Schmidt; Leonardo Pantoni; Domenico Inzitari; Gunhild Waldemar; Timo Erkinjuntti; Riita Mäntylä; Lars-Olof Wahlund; Frederik Barkhof
Impact of white matter hyperintensities scoring method on correlations with clinical data: the LADIS study.
Stroke; a journal of cerebral circulation 2006;37(3):836-40.
2006: Marjo S van der Knaap; Leo M E Smit; Frederik Barkhof; Y A L Pijnenburg; Sonja Zweegman; Hans W M Niessen; Saskia Imhof; Peter Heutink
Neonatal porencephaly and adult stroke related to mutations in collagen IV A1.
Annals of neurology 2006;59(3):504-11.
2006: Marjo S van der Knaap; V Ramesh; R Schiffmann; S Blaser; M Kyllerman; A Gholkar; D W Ellison; J Patrick van der Voorn; Silvy J M van Dooren; Cornelis Jakobs; Frederik Barkhof; Gajja S Salomons
Alexander disease: ventricular garlands and abnormalities of the medulla and spinal cord.
Neurology 2006;66(4):494-8.
2006: Alette M Wessels; Serge A R B Rombouts; Suat Simsek; Joost P A Kuijer; Piet J Kostense; Frederik Barkhof; Philip scheltens; Frank J Snoek; Robert J Heine
Microvascular disease in type 1 diabetes alters brain activation: a functional magnetic resonance imaging study.
Diabetes 2006;55(2):334-40.
2006: Y A L Pijnenburg; S N M Schoonenboom; Frederik Barkhof; DL Knol; Cees Mulder; Gerard J van Kamp; John C van Swieten; Philip scheltens
CSF biomarkers in frontotemporal lobar degeneration: relations with clinical characteristics, apolipoprotein E genotype, and neuroimaging.
Journal of neurology, neurosurgery, and psychiatry 2006;77(2):246-8.
2006: Maaike J Vos; Johannes Berkhof; Tjeerd J Postma; Otto S Hoekstra; Frederik Barkhof; Jan J Heimans
Thallium-201 SPECT: the optimal prediction of response in glioma therapy.
European journal of nuclear medicine and molecular imaging 2006;33(2):222-7.
2006: Laura A van de Pol; Anke Hensel; Frederik Barkhof; Hermann-Josef Gertz; Philip scheltens; Wiesje M van der Flier
Hippocampal atrophy in Alzheimer disease: age matters.
Neurology 2006;66(2):236-8.
2006: António J Bastos Leite; Wiesje M van der Flier; E C W van Straaten; Philip scheltens; Frederik Barkhof
Infratentorial abnormalities in vascular dementia.
Stroke; a journal of cerebral circulation 2006;37(1):105-10.
2006: Rutger Goekoop; Philip scheltens; Frederik Barkhof; Serge A R B Rombouts
Cholinergic challenge in Alzheimer patients and mild cognitive impairment differentially affects hippocampal activation--a pharmacological fMRI study.
Brain : a journal of neurology 2006;129(Pt 1):141-57.
2006: Andrea Semplicini; Piero Amodio; Gastone Leonetti; Cesare Cuspidi; Carlo Umiltà; Sami Schiff; Philip scheltens; Frederik Barkhof; Costanza Emanueli; Annachiara Cagnin; Gilberto Pizzolato; Luisa Macchini; Anna Realdi; Vladimir Royter; Natan M Bornstein; Paolo Madeddu
Diagnostic tools for the study of vascular cognitive dysfunction in hypertension and antihypertensive drug research.
Pharmacology & therapeutics 2006;109(1-2):274-83.
2006: Liselotte Gootjes; Anke Bouma; Jan Van Strien; Ronald A van Schijndel; Frederik Barkhof; Philip scheltens
Corpus callosum size correlates with asymmetric performance on a dichotic listening task in healthy aging but not in Alzheimer's disease.
Neuropsychologia 2006;44(2):208-17.
2005: Catharina M P Vos; Jeroen J G Geurts; Lisette Montagne; Elise S van Haastert; Lars Bö; Paul Van Der Valk; Frederik Barkhof; Helga E de Vries
Blood-brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis.
Neurobiology of disease 2005;20(3):953-60.
2005: Serge A R B Rombouts; Frederik Barkhof; Rutger Goekoop; Cornelis Stam; Philip scheltens
Altered resting state networks in mild cognitive impairment and mild Alzheimer's disease: an fMRI study.
Human brain mapping 2005;26(4):231-9.
2005: Frederik Barkhof; Ulrike Held; JH Simon; Martin Daumer; Franz Fazekas; Massimo Filippi; J A Frank; Ludwig Kappos; D Li; S Menzler; David H Miller; John Petkau; J Wolinsky
Predicting gadolinium enhancement status in MS patients eligible for randomized clinical trials.
Neurology 2005;65(9):1447-54.
2005: W J R van Ouwerkerk; Rob L M Strijers; Frederik Barkhof; Ulco Umans; W Peter Vandertop
Detection of root avulsion in the dominant C7 obstetric brachial plexus lesion: experience with three-dimensional constructive interference in steady-state magnetic resonance imaging and electrophysiology.
Neurosurgery 2005;57(5):930-40; discussion 930-40.
2005: Jessica M Nielsen; Tijmen Korteweg; Frederik Barkhof; Bernard Uitdehaag; Chris H Polman
Overdiagnosis of multiple sclerosis and magnetic resonance imaging criteria.
Annals of neurology 2005;58(5):781-3.
2005: Wiesje M van der Flier; E C W van Straaten; Frederik Barkhof; José M Ferro; Leonardo Pantoni; Anna Maria Basile; Domenico Inzitari; Timo Erkinjuntti; Lars-Olof Wahlund; Egill Rostrup; Reinhold Schmidt; Franz Fazekas; Philip scheltens
Medial temporal lobe atrophy and white matter hyperintensities are associated with mild cognitive deficits in non-disabled elderly people: the LADIS study.
Journal of neurology, neurosurgery, and psychiatry 2005;76(11):1497-500.
2005: R H C Lazeron; JB Boringa; M Schouten; Bernard Uitdehaag; Elisabeth Bergers; Jaap Lindeboom; M I Eikelenboom; Philip scheltens; Frederik Barkhof; Chris H Polman
Brain atrophy and lesion load as explaining parameters for cognitive impairment in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2005;11(5):524-31.
2005: Wiesje M van der Flier; E C W van Straaten; Frederik Barkhof; Ana Verdelho; Sofia Madureira; Leonardo Pantoni; Domenico Inzitari; Timo Erkinjuntti; Militta Crisby; Gunhild Waldemar; Reinhold Schmidt; Franz Fazekas; Philip scheltens
Small vessel disease and general cognitive function in nondisabled elderly: the LADIS study.
Stroke; a journal of cerebral circulation 2005;36(10):2116-20.
2005: Maarten H Lequin; Jeroen R Vermeulen; Ruurd M van Elburg; Frederik Barkhof; René F Kornelisse; Renate Swarte; Paul Govaert
Bacillus cereus meningoencephalitis in preterm infants: neuroimaging characteristics.
AJNR. American journal of neuroradiology 2005;26(8):2137-43.
2005: Jaume Sastre-Garriga; Gordon T Ingle; Marco Rovaris; Nieves Téllez; jasperse bas; Daniel R Altmann; B Benedetti; Valerie L Stevenson; Mara Cercignani; Siobhan M Leary; Frederik Barkhof; B Brochet; V Dousset; Massimo Filippi; Xavier Montalban; Nynke F Kalkers; Chris H Polman; Alex Rovira; David H Miller; Alan J Thompson
Long-term clinical outcome of primary progressive MS: predictive value of clinical and MRI data.
Neurology 2005;65(4):633-5.
2005: Serge A R B Rombouts; Rutger Goekoop; Cornelis Stam; Frederik Barkhof; Philip scheltens
Delayed rather than decreased BOLD response as a marker for early Alzheimer's disease.
NeuroImage 2005;26(4):1078-85.
2005: Arjan Minneboo; Bernard Uitdehaag; Herman J Ader; Frederik Barkhof; Chris H Polman; Jonas A Castelijns
Patterns of enhancing lesion evolution in multiple sclerosis are uniform within patients.
Neurology 2005;65(1):56-61.
2005: Jeroen J G Geurts; Petra J W Pouwels; Bernard Uitdehaag; Chris H Polman; Frederik Barkhof; Jonas A Castelijns
Intracortical lesions in multiple sclerosis: improved detection with 3D double inversion-recovery MR imaging.
Radiology 2005;236(1):254-60.
2005: Jan Van Strien; Rogier E Hagenbeek; Cornelis Stam; Serge A R B Rombouts; Frederik Barkhof
Changes in brain electrical activity during extended continuous word recognition.
NeuroImage 2005;26(3):952-9.
2005: Cees Mulder; Philip scheltens; Frederik Barkhof; Chad Gundy; Rob A Verstraeten; Frank-Erik De Leeuw
Low vitamin B6 levels are associated with white matter lesions in Alzheimer's disease.
Journal of the American Geriatrics Society 2005;53(6):1073-4.
2005: David Miller; Frederik Barkhof; Xavier Montalban; Alan Thompson; Massimo Filippi
Clinically isolated syndromes suggestive of multiple sclerosis, part 2: non-conventional MRI, recovery processes, and management.
Lancet neurology 2005;4(6):341-8.
2005: Frederik Barkhof; Robert C McKinstry
Quantifying spinal cord demyelination with magnetic transfer imaging.
Neurology 2005;64(10):1677-8.
2005: Dennis R Buis; Frank J Lagerwaard; Frederik Barkhof; Clemens M F Dirven; Geert Lycklama; O W M Meijer; René van den Berg; Hans A Langendijk; Ben Slotman; W Peter Vandertop
Stereotactic radiosurgery for brain AVMs: role of interobserver variation in target definition on digital subtraction angiography.
International journal of radiation oncology, biology, physics 2005;62(1):246-52.
2005: David Miller; Frederik Barkhof; Xavier Montalban; Alan Thompson; Massimo Filippi
Clinically isolated syndromes suggestive of multiple sclerosis, part I: natural history, pathogenesis, diagnosis, and prognosis.
Lancet neurology 2005;4(5):281-8.
2005: Tijmen Korteweg; Frederik Barkhof; Bernard Uitdehaag; Chris H Polman
How to use spinal cord magnetic resonance imaging in the McDonald diagnostic criteria for multiple sclerosis.
Annals of neurology 2005;57(4):606-7.
2005: Peer de Graaf; Frederik Barkhof; Annette C Moll; Saskia M Imhof; Dirk L Knol; Paul Van Der Valk; Jonas A Castelijns
Retinoblastoma: MR imaging parameters in detection of tumor extent.
Radiology 2005;235(1):197-207.
2005: Chris H Polman; Frederik Barkhof; Magnhild Sandberg-Wollheim; A Linde; O Nordle; T Nederman
Treatment with laquinimod reduces development of active MRI lesions in relapsing MS.
Neurology 2005;64(6):987-91.
2005: Jeroen J G Geurts; Lars Bö; Petra J W Pouwels; Jonas A Castelijns; Chris H Polman; Frederik Barkhof
Cortical lesions in multiple sclerosis: combined postmortem MR imaging and histopathology.
AJNR. American journal of neuroradiology 2005;26(3):572-7.
2005: J Patrick van der Voorn; Petra J W Pouwels; Wouter Kamphorst; James M Powers; Martin Lammens; Frederik Barkhof; Marjo S van der Knaap
Histopathologic correlates of radial stripes on MR images in lysosomal storage disorders.
AJNR. American journal of neuroradiology 2005;26(3):442-6.
2005: Odile A van den Heuvel; Dick J Veltman; Henk J Groenewegen; Danielle C Cath; Anton J L M van Balkom; Julie van Hartskamp; Frederik Barkhof; Richard van Dyck
Frontal-striatal dysfunction during planning in obsessive-compulsive disorder.
Archives of general psychiatry 2005;62(3):301-9.
2005: Rutger Goekoop; Erik J J Duschek; Dirk L Knol; Frederik Barkhof; JAN COEN NETELENBOS; Philip scheltens; Serge A R B Rombouts
Raloxifene exposure enhances brain activation during memory performance in healthy elderly males; its possible relevance to behavior.
NeuroImage 2005;25(1):63-75.
2005: Marjo S van der Knaap; Gajja S Salomons; Rong Li; Emilio Franzoni; Luiz González Gutiérrez-Solana; Leo M E Smit; Richard Robinson; Collin D Ferrie; Bruce Cree; Alyssa Reddy; Neil Thomas; Brenda Banwell; Frederik Barkhof; Cornelis Jakobs; Anne Johnson; Albee Messing; Michael Brenner
Unusual variants of Alexander's disease.
Annals of neurology 2005;57(3):327-38.
2005: Dick J Veltman; Michiel B de Ruiter; Serge A R B Rombouts; R H C Lazeron; Frederik Barkhof; Richard van Dyck; Raymond J Dolan; R Hans Phaf
Neurophysiological correlates of increased verbal working memory in high-dissociative participants: a functional MRI study.
Psychological medicine 2005;35(2):175-85.
2005: Hugo Vrenken; Frederik Barkhof; Bernard Uitdehaag; Jonas A Castelijns; Chris H Polman; Petra J W Pouwels
MR spectroscopic evidence for glial increase but not for neuro-axonal damage in MS normal-appearing white matter.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2005;53(2):256-66.
2005: Anda H van Stegeren; Rutger Goekoop; Walter Everaerd; Philip scheltens; Frederik Barkhof; Joost P A Kuijer; Serge A R B Rombouts
Noradrenaline mediates amygdala activation in men and women during encoding of emotional material.
NeuroImage 2005;24(3):898-909.
2005: Esther S C Korf; Philip scheltens; Frederik Barkhof; Frank-Erik De Leeuw
Blood pressure, white matter lesions and medial temporal lobe atrophy: closing the gap between vascular pathology and Alzheimer's disease?
Dementia and geriatric cognitive disorders 2005;20(6):331-7.
2005: Stefan Ropele; Massimo Filippi; Paola Valsasina; Tijmen Korteweg; Frederik Barkhof; Paul S Tofts; Rebecca Samson; David H Miller; Franz Fazekas
Assessment and correction of B1-induced errors in magnetization transfer ratio measurements.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2005;53(1):134-40.
2005: M Judith Eikelenboom; Joep Killestein; Thijs Izeboud; Nynke F Kalkers; Paul A Baars; René A W van Lier; Frederik Barkhof; Bernard Uitdehaag; Chris H Polman
Expression of adhesion molecules on peripheral lymphocytes predicts future lesion development in MS.
Journal of neuroimmunology 2005;158(1-2):222-30.
2004: António J Bastos Leite; Philip scheltens; Frederik Barkhof
Pathological aging of the brain: an overview.
Topics in magnetic resonance imaging : TMRI 2004;15(6):369-89.
2004: Rutger Goekoop; Serge A R B Rombouts; Cees Jonker; Anneke Hibbel; Dirk L Knol; Luc Truyen; Frederik Barkhof; Philip scheltens
Challenging the cholinergic system in mild cognitive impairment: a pharmacological fMRI study.
NeuroImage 2004;23(4):1450-9.
2004: E C W van Straaten; Philip scheltens; Frederik Barkhof
MRI and CT in the diagnosis of vascular dementia.
Journal of the neurological sciences 2004;226(1-2):9-12.
2004: Joost C J Bot; Erwin L A Blezer; Wouter Kamphorst; Geert J Lycklama a Nijeholt; Herman J Ader; Jonas A Castelijns; Klaas Nicolay Ig; Elisabeth Bergers; Rivka Ravid; Chris H Polman; Frederik Barkhof
The spinal cord in multiple sclerosis: relationship of high-spatial-resolution quantitative MR imaging findings to histopathologic results.
Radiology 2004;233(2):531-40.
2004: Konrad Rejdak; M Judith Eikelenboom; Axel Petzold; Edward J Thompson; Z Stelmasiak; R H C Lazeron; Frederik Barkhof; Chris H Polman; Bernard Uitdehaag; Gavin Giovannoni
CSF nitric oxide metabolites are associated with activity and progression of multiple sclerosis.
Neurology 2004;63(8):1439-45.
2004: Massimo Filippi; Marco Rovaris; Matilde Inglese; Frederik Barkhof; Nicola de Stefano; Steve Smith; Giancarlo Comi
Interferon beta-1a for brain tissue loss in patients at presentation with syndromes suggestive of multiple sclerosis: a randomised, double-blind, placebo-controlled trial.
Lancet 2004;364(9444):1489-96.
2004: Giorgos Karas; Philip scheltens; Serge A R B Rombouts; P J Visser; Ronald A van Schijndel; Nick C Fox; Frederik Barkhof
Global and local gray matter loss in mild cognitive impairment and Alzheimer's disease.
NeuroImage 2004;23(2):708-16.
2004: R H C Lazeron; Serge A R B Rombouts; Philip scheltens; Chris H Polman; Frederik Barkhof
An fMRI study of planning-related brain activity in patients with moderately advanced multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2004;10(5):549-55.
2004: Mario H J Vogt; Sarah Floris; Joep Killestein; Dirk L Knol; Monique Smits; Frederik Barkhof; Chris H Polman; Lex Nagelkerken
Osteopontin levels and increased disease activity in relapsing-remitting multiple sclerosis patients.
Journal of neuroimmunology 2004;155(1-2):155-60.
2004: Hans M Schrijver; J B A Crusius; M Asunçion García-González; Chris H Polman; Amado Salvador Peña; Frederik Barkhof; Bernard Uitdehaag
Gender-related association between the TGFB1+869 polymorphism and multiple sclerosis.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2004;24(9):536-42.
2004: Frederik Barkhof
Assessing treatment effects on axonal loss--evidence from MRI monitored clinical trials.
Journal of neurology 2004;251 Suppl 4():IV6-12.
2004: Jeroen J G Geurts; Frederik Barkhof; Jonas A Castelijns; Bernard Uitdehaag; Chris H Polman; Petra J W Pouwels
Quantitative 1H-MRS of healthy human cortex, hippocampus, and thalamus: metabolite concentrations, quantification precision, and reproducibility.
Journal of magnetic resonance imaging : JMRI 2004;20(3):366-71.
2004: Frank-Erik De Leeuw; Frederik Barkhof; Philip scheltens
Alzheimer's disease--one clinical syndrome, two radiological expressions: a study on blood pressure.
Journal of neurology, neurosurgery, and psychiatry 2004;75(9):1270-4.
2004: Reinhold Schmidt; Philip scheltens; Timo Erkinjuntti; L Pantoni; H S Markus; Anders Wallin; Frederik Barkhof; Franz Fazekas
White matter lesion progression: a surrogate endpoint for trials in cerebral small-vessel disease.
Neurology 2004;63(1):139-44.
2004: J N P Zwemmer; Tineke Van Veen; Lisa van Winsen; Gerard J van Kamp; Frederik Barkhof; Chris H Polman; Bernard Uitdehaag
No major association of ApoE genotype with disease characteristics and MRI findings in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2004;10(3):272-7.
2004: Hans M Schrijver; Tineke Van Veen; Martine J Van Belzen; J B A Crusius; Amado Salvador Peña; Frederik Barkhof; C H Polman; Bernard Uitdehaag
Polymorphisms in the genes encoding interferon-gamma and interferon-gamma receptors in multiple sclerosis.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 2004;31(3):133-40.
2004: Niels D Prins; E C W van Straaten; Ewoud J van Dijk; M Simoni; R A van Schijndel; Henri A Vrooman; Peter J Koudstaal; Philip scheltens; Monique Breteler; Frederik Barkhof
Measuring progression of cerebral white matter lesions on MRI: visual rating and volumetrics.
Neurology 2004;62(9):1533-9.
2004: Lars Bö; Jeroen J G Geurts; Rivka Ravid; Frederik Barkhof
Magnetic resonance imaging as a tool to examine the neuropathology of multiple sclerosis.
Neuropathology and applied neurobiology 2004;30(2):106-17.
2004: Sarah Floris; Annette van der Goes; Joep Killestein; Dirk L Knol; Frederik Barkhof; Chris H Polman; Christine D Dijkstra; Helga E de Vries; Jan F Meilof
Monocyte activation and disease activity in multiple sclerosis. A longitudinal analysis of serum MRP8/14 levels.
Journal of neuroimmunology 2004;148(1-2):172-7.
2004: Marjo S van der Knaap; Gerre Vermeulen; Frederik Barkhof; Augustinus A M Hart; Gerard LOEBER; Jan F L Weel
Pattern of white matter abnormalities at MR imaging: use of polymerase chain reaction testing of Guthrie cards to link pattern with congenital cytomegalovirus infection.
Radiology 2004;230(2):529-36.
2004: António J Bastos Leite; E C W van Straaten; Philip scheltens; Geert Lycklama; Frederik Barkhof
Thalamic lesions in vascular dementia: low sensitivity of fluid-attenuated inversion recovery (FLAIR) imaging.
Stroke; a journal of cerebral circulation 2004;35(2):415-9.
2004: Frank-Erik De Leeuw; Frederik Barkhof; Philip scheltens
White matter lesions and hippocampal atrophy in Alzheimer's disease.
Neurology 2004;62(2):310-2.
2004: Joost C J Bot; Frederik Barkhof; Chris H Polman; Geert Lycklama à Nijeholt; Vincent de Groot; Elisabeth Bergers; Herman J Ader; Jonas A Castelijns
Spinal cord abnormalities in recently diagnosed MS patients: added value of spinal MRI examination.
Neurology 2004;62(2):226-33.
2004: M W G Vandenbroucke; Rutger Goekoop; Erik J J Duschek; JAN COEN NETELENBOS; Joost P A Kuijer; Frederik Barkhof; Philip scheltens; Serge A R B Rombouts
Interindividual differences of medial temporal lobe activation during encoding in an elderly population studied by fMRI.
NeuroImage 2004;21(1):173-80.
2003: Franca A Gerards; Melanie A J Engels; Frederik Barkhof; Frank A M van den Dungen; R Jeroen Vermeulen; John M G van Vugt
Prenatal diagnosis of aneurysms of the vein of Galen (vena magna cerebri) with conventional sonography, three-dimensional sonography, and magnetic resonance imaging: report of 2 cases.
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 2003;22(12):1363-8.
2003: Tineke Van Veen; Hans M Schrijver; Antoon Zwiers; J B A Crusius; Dirk L Knol; Nynke F Kalkers; Marja L Laine; Frederik Barkhof; Amado Salvador Peña; Chris H Polman; Bernard Uitdehaag
The interleukin-1 gene family in multiple sclerosis susceptibility and disease course.
Multiple sclerosis (Houndmills, Basingstoke, England) 2003;9(6):535-9.
2003: Marianne A A van Walderveen; Ronald A van Schijndel; Petra J W Pouwels; Chris H Polman; Frederik Barkhof
Multislice T1 relaxation time measurements in the brain using IR-EPI: reproducibility, normal values, and histogram analysis in patients with multiple sclerosis.
Journal of magnetic resonance imaging : JMRI 2003;18(6):656-64.
2003: Tineke Van Veen; Lisa van Winsen; J B A Crusius; Nynke F Kalkers; Frederik Barkhof; Amado Salvador Peña; Chris H Polman; Bernard Uitdehaag
[Alpha]B-crystallin genotype has impact on the multiple sclerosis phenotype.
Neurology 2003;61(9):1245-9.
2003: Serge A R B Rombouts; Cornelis Stam; Joost P A Kuijer; Philip scheltens; Frederik Barkhof
Identifying confounds to increase specificity during a "no task condition". Evidence for hippocampal connectivity using fMRI.
NeuroImage 2003;20(2):1236-45.
2003: Maaike J Vos; Otto S Hoekstra; Frederik Barkhof; Johannes Berkhof; Jan J Heimans; Cees J van Groeningen; W Peter Vandertop; Ben Slotman; Tjeerd J Postma
Thallium-201 single-photon emission computed tomography as an early predictor of outcome in recurrent glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(19):3559-65.
2003: R H C Lazeron; Serge A R B Rombouts; Leo De Sonneville; Frederik Barkhof; Philip scheltens
A paced visual serial addition test for fMRI.
Journal of the neurological sciences 2003;213(1-2):29-34.
2003: Joep Killestein; M Judith Eikelenboom; Thijs Izeboud; Nynke F Kalkers; Herman J Adèr; Frederik Barkhof; René A W van Lier; Bernard Uitdehaag; Chris H Polman
Cytokine producing CD8+ T cells are correlated to MRI features of tissue destruction in MS.
Journal of neuroimmunology 2003;142(1-2):141-8.
2003: Geert Lycklama; Alan Thompson; Massimo Filippi; David Miller; Chris H Polman; Franz Fazekas; Frederik Barkhof
Spinal-cord MRI in multiple sclerosis.
Lancet neurology 2003;2(9):555-62.
2003: Chris H Polman; Frederik Barkhof; Ludwig Kappos; Carlo Pozzilli; Rupert Sandbrink; Frank Dahlke; Peter Jakobs; A Lorenz
Oral interferon beta-1a in relapsing-remitting multiple sclerosis: a double-blind randomized study.
Multiple sclerosis (Houndmills, Basingstoke, England) 2003;9(4):342-8.
2003: Frederik Barkhof; Wolfgang Bruck; Christianne J M De Groot; Elisabeth Bergers; Sandra Hulshof; Jeroen J G Geurts; Chris H Polman; Paul Van Der Valk
Remyelinated lesions in multiple sclerosis: magnetic resonance image appearance.
Archives of neurology 2003;60(8):1073-81.
2003: E C W van Straaten; Philip scheltens; Dirk L Knol; Mark A Van Buchem; Ewoud J van Dijk; Paul A M Hofman; Giorgos Karas; Olafur Kjartansson; Frank-Erik De Leeuw; Niels D Prins; Reinhold Schmidt; Marieke C Visser; Henry C Weinstein; Frederik Barkhof
Operational definitions for the NINDS-AIREN criteria for vascular dementia: an interobserver study.
Stroke; a journal of cerebral circulation 2003;34(8):1907-12.
2003: Tineke Van Veen; J B A Crusius; Lisa van Winsen; Bing Xia; Frederik Barkhof; A Salvador Peña; Chris H Polman; Bernard Uitdehaag
CTLA-4 and CD28 gene polymorphisms in susceptibility, clinical course and progression of multiple sclerosis.
Journal of neuroimmunology 2003;140(1-2):188-93.
2003: Serge A R B Rombouts; John C van Swieten; Y A L Pijnenburg; Rutger Goekoop; Frederik Barkhof; Philip scheltens
Loss of frontal fMRI activation in early frontotemporal dementia compared to early AD.
Neurology 2003;60(12):1904-8.
2003: Frederik Barkhof; Mara Rocca; Gordon Francis; Jan-Hein T M van Waesberghe; Bernard Uitdehaag; Otto R Hommes; Hans-Peter Hartung; Luca Durelli; Gilles Edan; Oscar Fernández; Pierette Seeldrayers; Per Sørensen; Simon Margrie; Marco Rovaris; Giancarlo Comi; Massimo Filippi
Validation of diagnostic magnetic resonance imaging criteria for multiple sclerosis and response to interferon beta1a.
Annals of neurology 2003;53(6):718-24.
2003: Luba Lopatinskaya; Anette H H van Boxel-Dezaire; Frederik Barkhof; Chris H Polman; Cornelis J Lucas; Lex Nagelkerken
The development of clinical activity in relapsing-remitting MS is associated with a decrease of FasL mRNA and an increase of Fas mRNA in peripheral blood.
Journal of neuroimmunology 2003;138(1-2):123-31.
2003: R Jeroen Vermeulen; Willem P F Fetter; L Hendrikx; Petra E M Van Schie; Marjo S van der Knaap; Frederik Barkhof
Diffusion-weighted MRI in severe neonatal hypoxic ischaemia: the white cerebrum.
Neuropediatrics 2003;34(2):72-6.
2003: Giorgos Karas; E J Burton; Serge A R B Rombouts; Ronald A van Schijndel; John T O'Brien; Philip scheltens; Ian G McKeith; D Williams; Clive G Ballard; Frederik Barkhof
A comprehensive study of gray matter loss in patients with Alzheimer's disease using optimized voxel-based morphometry.
NeuroImage 2003;18(4):895-907.
2003: Mark A Horsfield; Gareth Barker; Frederik Barkhof; David H Miller; Alan J Thompson; Massimo Filippi
Guidelines for using quantitative magnetization transfer magnetic resonance imaging for monitoring treatment of multiple sclerosis.
Journal of magnetic resonance imaging : JMRI 2003;17(4):389-97.
2003: Matilde Inglese; Jan-Hein T M van Waesberghe; Marco Rovaris; Karola Beckmann; Frederik Barkhof; D Hahn; Ludwig Kappos; David H Miller; Chris H Polman; Carlo Pozzilli; Alan J Thompson; Tarek A Yousry; Klaus Wagner; Giancarlo Comi; Massimo Filippi
The effect of interferon beta-1b on quantities derived from MT MRI in secondary progressive MS.
Neurology 2003;60(5):853-60.
2003: Maaike J Vos; Bernard Uitdehaag; Frederik Barkhof; Jan J Heimans; H C Baayen; Willem Boogerd; Jonas A Castelijns; P H M Elkhuizen; Tjeerd J Postma
Interobserver variability in the radiological assessment of response to chemotherapy in glioma.
Neurology 2003;60(5):826-30.
2003: Geert Lycklama à Nijeholt; Frederik Barkhof
Differences between subgroups of MS: MRI findings and correlation with histopathology.
Journal of the neurological sciences 2003;206(2):173-4.
2003: Odile A van den Heuvel; Henk J Groenewegen; Frederik Barkhof; R H C Lazeron; Richard van Dyck; Dick J Veltman
Frontostriatal system in planning complexity: a parametric functional magnetic resonance version of Tower of London task.
NeuroImage 2003;18(2):367-74.
2003: Marjo S van der Knaap; Patrick van der Voorn; Frederik Barkhof; Rudy Van Coster; Ingeborg Krägeloh-Mann; Annette Feigenbaum; Susan Blaser; Johan S H Vles; Peter Rieckmann; Petra J W Pouwels
A new leukoencephalopathy with brainstem and spinal cord involvement and high lactate.
Annals of neurology 2003;53(2):252-8.
2003: M Judith Eikelenboom; Axel Petzold; R H C Lazeron; E Silber; Moad K Sharief; Edward J Thompson; Frederik Barkhof; Gavin Giovannoni; Chris H Polman; Bernard Uitdehaag
Multiple sclerosis: Neurofilament light chain antibodies are correlated to cerebral atrophy.
Neurology 2003;60(2):219-23.
2003: Frederik Barkhof
Guidelines for brain imaging in vascular dementia clinical trials.
International psychogeriatrics / IPA 2003;15 Suppl 1():273-6.
2003: Philip scheltens; Frederik Barkhof; Franz Fazekas
White-matter changes on MRI as surrogate marker.
International psychogeriatrics / IPA 2003;15 Suppl 1():261-5.
2002: Elisabeth Bergers; Joost C J Bot; Christianne J M De Groot; Chris H Polman; Geert Lycklama à Nijeholt; Jonas A Castelijns; Paul Van Der Valk; Frederik Barkhof
Axonal damage in the spinal cord of MS patients occurs largely independent of T2 MRI lesions.
Neurology 2002;59(11):1766-71.
2002: Nynke F Kalkers; Frederik Barkhof; Elisabeth Bergers; Ronald A van Schijndel; Chris H Polman
The effect of the neuroprotective agent riluzole on MRI parameters in primary progressive multiple sclerosis: a pilot study.
Multiple sclerosis (Houndmills, Basingstoke, England) 2002;8(6):532-3.
2002: Leonardo Pantoni; Michela Simoni; Giovanni Pracucci; Reinhold Schmidt; Frederik Barkhof; Domenico Inzitari
Visual rating scales for age-related white matter changes (leukoaraiosis): can the heterogeneity be reduced?
Stroke; a journal of cerebral circulation 2002;33(12):2827-33.
2002: M Judith Eikelenboom; Joep Killestein; Thijs Izeboud; Nynke F Kalkers; René A W van Lier; Frederik Barkhof; Bernard Uitdehaag; Chris H Polman
Chemokine receptor expression on T cells is related to new lesion development in multiple sclerosis.
Journal of neuroimmunology 2002;133(1-2):225-32.
2002: Serge A R B Rombouts; Frederik Barkhof; Catharina S Van Meel; Philip scheltens
Alterations in brain activation during cholinergic enhancement with rivastigmine in Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 2002;73(6):665-71.
2002: Rogier E Hagenbeek; Serge A R B Rombouts; Bob W van Dijk; Frederik Barkhof
Determination of individual stimulus--response curves in the visual cortex.
Human brain mapping 2002;17(4):244-50.
2002: Frederik Barkhof
Whole-brain T1-relaxation time measurements in multiple sclerosis.
Journal of neurology 2002;249(10):1451-2.
2002: Emma J Burton; Giorgos Karas; Sean M Paling; Robert Barber; E David Williams; Clive G Ballard; Ian G McKeith; Philip scheltens; Frederik Barkhof; John T O'Brien
Patterns of cerebral atrophy in dementia with Lewy bodies using voxel-based morphometry.
NeuroImage 2002;17(2):618-30.
2002: Nynke F Kalkers; Najim Ameziane; Joost C J Bot; Arjan Minneboo; Chris H Polman; Frederik Barkhof
Longitudinal brain volume measurement in multiple sclerosis: rate of brain atrophy is independent of the disease subtype.
Archives of neurology 2002;59(10):1572-6.
2002: E L J Hoogervorst; Chris H Polman; Frederik Barkhof
Cerebral volume changes in multiple sclerosis patients treated with high-dose intravenous methylprednisolone.
Multiple sclerosis (Houndmills, Basingstoke, England) 2002;8(5):415-9.
2002: Nynke F Kalkers; Hugo Vrenken; Bernard Uitdehaag; Chris H Polman; Frederik Barkhof
Brain atrophy in multiple sclerosis: impact of lesions and of damage of whole brain tissue.
Multiple sclerosis (Houndmills, Basingstoke, England) 2002;8(5):410-4.
2002: I Leng Tan; Ronald A van Schijndel; Petra J W Pouwels; Herman J Adèr; Frederik Barkhof
Serial isotropic three-dimensional fast FLAIR imaging: using image registration and subtraction to reveal active multiple sclerosis lesions.
AJR. American journal of roentgenology 2002;179(3):777-82.
2002: David H Miller; Frederik Barkhof; Joseph A Frank; Geoffrey J M Parker; Alan J Thompson
Measurement of atrophy in multiple sclerosis: pathological basis, methodological aspects and clinical relevance.
Brain : a journal of neurology 2002;125(Pt 8):1676-95.
2002: Tineke Van Veen; Nynke F Kalkers; J B A Crusius; Lisa van Winsen; Frederik Barkhof; Peter J H Jongen; Amado Salvador Peña; Chris H Polman; Bernard Uitdehaag
The FAS-670 polymorphism influences susceptibility to multiple sclerosis.
Journal of neuroimmunology 2002;128(1-2):95-100.
2002: I Leng Tan; Ronald A van Schijndel; Franz Fazekas; Massimo Filippi; Peter Freitag; David H Miller; Tarek A Yousry; Petra J W Pouwels; Herman J Adèr; Frederik Barkhof
Image registration and subtraction to detect active T(2) lesions in MS: an interobserver study.
Journal of neurology 2002;249(6):767-73.
2002: Frederik Barkhof
The clinico-radiological paradox in multiple sclerosis revisited.
Current opinion in neurology 2002;15(3):239-45.
2002: Philip scheltens; Nick C Fox; Frederik Barkhof; Charles DeCarli
Structural magnetic resonance imaging in the practical assessment of dementia: beyond exclusion.
Lancet neurology 2002;1(1):13-21.
2002: Elisabeth Bergers; Joost C J Bot; Paul Van Der Valk; Jonas A Castelijns; Geert J Lycklama a Nijeholt; Wouter Kamphorst; Chris H Polman; Erwin L A Blezer; Klaas Nicolay; Rivka Ravid; Frederik Barkhof
Diffuse signal abnormalities in the spinal cord in multiple sclerosis: direct postmortem in situ magnetic resonance imaging correlated with in vitro high-resolution magnetic resonance imaging and histopathology.
Annals of neurology 2002;51(5):652-6.
2002: I Leng Tan; Ronald A van Schijndel; Marianne A A van Walderveen; Marcel Quist; Reinhard Bos; Petra J W Pouwels; Pol Desmedt; Herman J Adèr; Frederik Barkhof
Magnetic resonance image registration in multiple sclerosis: comparison with repositioning error and observer-based variability.
Journal of magnetic resonance imaging : JMRI 2002;15(5):505-10.
2002: Joep Killestein; Martijn Rep; Jan F Meilof; Herman J Adèr; Bernard Uitdehaag; Frederik Barkhof; René A W van Lier; Chris H Polman
Seasonal variation in immune measurements and MRI markers of disease activity in MS.
Neurology 2002;58(7):1077-80.
2002: Gordon T Ingle; Valerie L Stevenson; David H Miller; Siobhan M Leary; Marco Rovaris; Frederik Barkhof; B Brochet; V Dousset; Massimo Filippi; Xavier Montalban; Nynke F Kalkers; Chris H Polman; Alex Rovira; Alan J Thompson
Two-year follow-up study of primary and transitional progressive multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2002;8(2):108-14.
2002: Joost C J Bot; Frederik Barkhof; Geert Lycklama à Nijeholt; Dirkjan van Schaardenburg; Alexandre E Voskuyl; Herman J Ader; Jolanda A L Pijnenburg; Chris H Polman; Bernard Uitdehaag; E G J Vermeulen; Jonas A Castelijns
Differentiation of multiple sclerosis from other inflammatory disorders and cerebrovascular disease: value of spinal MR imaging.
Radiology 2002;223(1):46-56.
2002: Joep Killestein; Tomas Olsson; Erik Wallström; Anders Svenningsson; Mohsen Khademi; Lance D Blumhardt; Jan Fagius; Jan Hillert; Anne-Marie Landtblom; Charlotte Edenius; Leopold Arfors; Frederik Barkhof; Chris H Polman
Antibody-mediated suppression of Vbeta5.2/5.3(+) T cells in multiple sclerosis: results from an MRI-monitored phase II clinical trial.
Annals of neurology 2002;51(4):467-74.
2002: I Leng Tan; Petra J W Pouwels; Ronald A van Schijndel; Herman J Adèr; Radu A Manoliu; Frederik Barkhof
Isotropic 3D fast FLAIR imaging of the brain in multiple sclerosis patients: initial experience.
European radiology 2002;12(3):559-67.
2002: A H C van der Meijs; I Leng Tan; Frederik Barkhof
Incidence of enhancement of the trigeminal nerve on MRI in patients with multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2002;8(1):64-7.
2002: Frederik Barkhof; Philip scheltens
Imaging of white matter lesions.
Cerebrovascular diseases (Basel, Switzerland) 2002;13 Suppl 2():21-30.
2001: PD Molyneux; Gareth Barker; Frederik Barkhof; Karola Beckmann; Frank Dahlke; Massimo Filippi; M Ghazi; D Hahn; David G MacManus; Chris H Polman; Carlo Pozzilli; Ludwig Kappos; Alan J Thompson; Klaus Wagner; Tarek A Yousry; David H Miller
Clinical-MRI correlations in a European trial of interferon beta-1b in secondary progressive MS.
Neurology 2001;57(12):2191-7.
2001: Peter A Brex; PD Molyneux; P Smiddy; Frederik Barkhof; Massimo Filippi; Tarek A Yousry; D Hahn; Y Rolland; O Salonen; Carlo Pozzilli; Chris H Polman; Alan J Thompson; Ludwig Kappos; David H Miller
The effect of IFNbeta-1b on the evolution of enhancing lesions in secondary progressive MS.
Neurology 2001;57(12):2185-90.
2001: Nynke F Kalkers; Elisabeth Bergers; Jonas A Castelijns; Marianne A A van Walderveen; Joost C J Bot; Herman J Adèr; Chris H Polman; Frederik Barkhof
Optimizing the association between disability and biological markers in MS.
Neurology 2001;57(7):1253-8.
2001: Joep Killestein; Nynke F Kalkers; Jan F Meilof; Frederik Barkhof; René A W van Lier; Chris H Polman
TNFalpha production by CD4(+) T cells predicts long-term increase in lesion load on MRI in MS.
Neurology 2001;57(6):1129-31.
2001: I Leng Tan; Ronald A van Schijndel; Franz Fazekas; Massimo Filippi; P Freitag; David H Miller; Tarek A Yousry; Petra J W Pouwels; Herman J Adèr; M J Quist; Frederik Barkhof
Improved interobserver agreement for visual detection of active T2 lesions on serial MR scans in multiple sclerosis using image registration.
Journal of neurology 2001;248(9):789-94.
2001: Joep Killestein; Martijn Rep; Frederik Barkhof; Marijke Th L Roos; Herman J Adèr; René A W van Lier; Chris H Polman
Active MRI lesion appearance in MS patients is preceded by fluctuations in circulating T-helper 1 and 2 cells.
Journal of neuroimmunology 2001;118(2):286-94.
2001: Christianne J M De Groot; Elisabeth Bergers; Wouter Kamphorst; Rivka Ravid; Chris H Polman; Frederik Barkhof; Paul Van Der Valk
Post-mortem MRI-guided sampling of multiple sclerosis brain lesions: increased yield of active demyelinating and (p)reactive lesions.
Brain : a journal of neurology 2001;124(Pt 8):1635-45.
2001: Serge A R B Rombouts; Frederik Barkhof; Menno P Witter; WC Machielsen; Philip scheltens
Anterior medial temporal lobe activation during attempted retrieval of encoded visuospatial scenes: an event-related fMRI study.
NeuroImage 2001;14(1 Pt 1):67-76.
2001: Frederik Barkhof; Jan-Hein T M van Waesberghe; Massimo Filippi; Tarek A Yousry; David H Miller; D Hahn; Alan J Thompson; Ludwig Kappos; P Brex; Carlo Pozzilli; Chris H Polman
T(1) hypointense lesions in secondary progressive multiple sclerosis: effect of interferon beta-1b treatment.
Brain : a journal of neurology 2001;124(Pt 7):1396-402.
2001: Maria Pia Sormani; David H Miller; Giancarlo Comi; Frederik Barkhof; Marco Rovaris; P Bruzzi; Massimo Filippi
Clinical trials of multiple sclerosis monitored with enhanced MRI: new sample size calculations based on large data sets.
Journal of neurology, neurosurgery, and psychiatry 2001;70(4):494-9.
2001: Nynke F Kalkers; Rogier Q Hintzen; Jan-Hein T M van Waesberghe; R H C Lazeron; Ronald A van Schijndel; Herman J Adèr; Chris H Polman; Frederik Barkhof
Magnetization transfer histogram parameters reflect all dimensions of MS pathology, including atrophy.
Journal of the neurological sciences 2001;184(2):155-62.
2001: Simone J M Neele; Serge A R B Rombouts; M A Bierlaagh; Frederik Barkhof; Philip scheltens; JAN COEN NETELENBOS
Raloxifene affects brain activation patterns in postmenopausal women during visual encoding.
The Journal of clinical endocrinology and metabolism 2001;86(3):1422-4.
2001: Nynke F Kalkers; L Bergers; Vincent de Groot; R H C Lazeron; Marianne A A van Walderveen; Bernard Uitdehaag; Chris H Polman; Frederik Barkhof
Concurrent validity of the MS Functional Composite using MRI as a biological disease marker.
Neurology 2001;56(2):215-9.
2001: Marianne A A van Walderveen; Geert J Lycklama a Nijeholt; Herman J Adèr; Peter J H Jongen; Chris H Polman; Jonas A Castelijns; Frederik Barkhof
Hypointense lesions on T1-weighted spin-echo magnetic resonance imaging: relation to clinical characteristics in subgroups of patients with multiple sclerosis.
Archives of neurology 2001;58(1):76-81.
2001: G J Nijeholt; Elisabeth Bergers; Wouter Kamphorst; Joost C J Bot; Klaas Nicolay; Jonas A Castelijns; Jan-Hein T M van Waesberghe; Rivka Ravid; Chris H Polman; Frederik Barkhof
Post-mortem high-resolution MRI of the spinal cord in multiple sclerosis: a correlative study with conventional MRI, histopathology and clinical phenotype.
Brain : a journal of neurology 2001;124(Pt 1):154-66.
2000: Frederik Barkhof; Aad Verrips; P Wesseling; Marjo S van der Knaap; B G M van Engelen; Fons J M Gabreëls; A Keyser; Ron A Wevers; Jakob Valk
Cerebrotendinous xanthomatosis: the spectrum of imaging findings and the correlation with neuropathologic findings.
Radiology 2000;217(3):869-76.
2000: Frederik Barkhof; Giorgos Karas; Marianne A A van Walderveen
T1 hypointensities and axonal loss.
Neuroimaging clinics of North America 2000;10(4):739-52 ,ix.
2000: W J R van Ouwerkerk; Johannes A van der Sluijs; Frans Nollet; Frederik Barkhof; Albert C J Slooff
Management of obstetric brachial plexus lesions: state of the art and future developments.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2000;16(10-11):638-44.
2000: Serge A R B Rombouts; Frederik Barkhof; Dick J Veltman; WC Machielsen; Menno P Witter; M A Bierlaagh; R H C Lazeron; Jakob Valk; Philip scheltens
Functional MR imaging in Alzheimer's disease during memory encoding.
AJNR. American journal of neuroradiology 2000;21(10):1869-75.
2000: PD Molyneux; Ludwig Kappos; Chris H Polman; Carlo Pozzilli; Frederik Barkhof; Massimo Filippi; Tarek A Yousry; D Hahn; Klaus Wagner; M Ghazi; Karola Beckmann; Frank Dahlke; N Losseff; Gareth Barker; Alan J Thompson; David H Miller
The effect of interferon beta-1b treatment on MRI measures of cerebral atrophy in secondary progressive multiple sclerosis. European Study Group on Interferon beta-1b in secondary progressive multiple sclerosis.
Brain : a journal of neurology 2000;123 ( Pt 11)():2256-63.
2000: R H C Lazeron; Serge A R B Rombouts; WC Machielsen; Philip scheltens; Menno P Witter; Harry Uylings; Frederik Barkhof
Visualizing brain activation during planning: the tower of London test adapted for functional MR imaging.
AJNR. American journal of neuroradiology 2000;21(8):1407-14.
2000: R H C Lazeron; DW Langdon; Massimo Filippi; Jan-Hein T M van Waesberghe; Valerie L Stevenson; JB Boringa; D Origgi; Alan J Thompson; M Falautano; Chris H Polman; Frederik Barkhof
Neuropsychological impairment in multiple sclerosis patients: the role of (juxta)cortical lesion on FLAIR.
Multiple sclerosis (Houndmills, Basingstoke, England) 2000;6(4):280-5.
2000: PD Molyneux; Peter A Brex; C Fogg; S Lewis; C Middleditch; Frederik Barkhof; Maria Pia Sormani; Massimo Filippi; David H Miller
The precision of T1 hypointense lesion volume quantification in multiple sclerosis treatment trials: a multicenter study.
Multiple sclerosis (Houndmills, Basingstoke, England) 2000;6(4):237-40.
2000: I Leng Tan; Ronald A van Schijndel; Petra J W Pouwels; Marianne A A van Walderveen; Jürgen Reichenbach; Radu A Manoliu; Frederik Barkhof
MR venography of multiple sclerosis.
AJNR. American journal of neuroradiology 2000;21(6):1039-42.
2000: Alan J Thompson; Xavier Montalban; Frederik Barkhof; B Brochet; Massimo Filippi; David H Miller; Chris H Polman; Valerie L Stevenson; WI McDonald
Diagnostic criteria for primary progressive multiple sclerosis: a position paper.
Annals of neurology 2000;47(6):831-5.
2000: Valerie L Stevenson; David H Miller; Siobhan M Leary; Marco Rovaris; Frederik Barkhof; B Brochet; V Dousset; Massimo Filippi; R Hintzen; Xavier Montalban; Chris H Polman; Alex Rovira; J de Sa; Alan J Thompson
One year follow up study of primary and transitional progressive multiple sclerosis.
Journal of neurology, neurosurgery, and psychiatry 2000;68(6):713-8.
2000: S A Rombouts; Frederik Barkhof; Menno P Witter; Philip scheltens
Unbiased whole-brain analysis of gray matter loss in Alzheimer's disease.
Neuroscience letters 2000;285(3):231-3.
2000: Geert Lycklama à Nijeholt; Jonas A Castelijns; R H C Lazeron; Jan-Hein T M van Waesberghe; Chris H Polman; Bernard Uitdehaag; Frederik Barkhof
Magnetization transfer ratio of the spinal cord in multiple sclerosis: relationship to atrophy and neurologic disability.
Journal of neuroimaging : official journal of the American Society of Neuroimaging 2000;10(2):67-72.
2000: I Leng Tan; Geert Lycklama à Nijeholt; Chris H Polman; Herman J Adèr; Frederik Barkhof
Linomide in the treatment of multiple sclerosis: MRI results from prematurely terminated phase-III trials.
Multiple sclerosis (Houndmills, Basingstoke, England) 2000;6(2):99-104.
2000: Nynke F Kalkers; Vincent de Groot; R H C Lazeron; Joep Killestein; Herman J Adèr; Frederik Barkhof; Gustaaf J Lankhorst; Chris H Polman
MS functional composite: relation to disease phenotype and disability strata.
Neurology 2000;54(6):1233-9.
2000: WC Machielsen; Serge A R B Rombouts; Frederik Barkhof; Philip scheltens; Menno P Witter
FMRI of visual encoding: reproducibility of activation.
Human brain mapping 2000;9(3):156-64.
2000: Lilian T L Sie; Frederik Barkhof; Harry N Lafeber; Jakob Valk; Marjo S van der Knaap
Value of fluid-attenuated inversion recovery sequences in early MRI of the brain in neonates with a perinatal hypoxic-ischemic encephalopathy.
European radiology 2000;10(10):1594-601.
2000: Menno P Witter; PA Naber; Theo van Haeften; WC Machielsen; Serge A R B Rombouts; Frederik Barkhof; Philip scheltens; Fernando Lopes da Silva
Cortico-hippocampal communication by way of parallel parahippocampal-subicular pathways.
Hippocampus 2000;10(4):398-410.
2000: Joost C J Bot; Frederik Barkhof; Geert Lycklama à Nijeholt; Elisabeth Bergers; Chris H Polman; Herman J Adèr; Jonas A Castelijns
Comparison of a conventional cardiac-triggered dual spin-echo and a fast STIR sequence in detection of spinal cord lesions in multiple sclerosis.
European radiology 2000;10(5):753-8.
2000: PD Molyneux; David H Miller; Massimo Filippi; Tarek A Yousry; Ludwig Kappos; Claudio Gasperini; H J Adèr; Frederik Barkhof
The use of magnetic resonance imaging in multiple sclerosis treatment trials: power calculations for annual lesion load measurement.
Journal of neurology 2000;247(1):34-40.
2000: Geert Lycklama à Nijeholt; Bernard Uitdehaag; Elisabeth Bergers; Jonas A Castelijns; Chris H Polman; Frederik Barkhof
Spinal cord magnetic resonance imaging in suspected multiple sclerosis.
European radiology 2000;10(2):368-76.
1999: Jan-Hein T M van Waesberghe; Wouter Kamphorst; Christianne J M De Groot; Marianne A A van Walderveen; Jonas A Castelijns; Rivka Ravid; Geert Lycklama à Nijeholt; Paul Van Der Valk; Chris H Polman; Alan J Thompson; Frederik Barkhof
Axonal loss in multiple sclerosis lesions: magnetic resonance imaging insights into substrates of disability.
Annals of neurology 1999;46(5):747-54.
1999: Marco Rovaris; Frederik Barkhof; Stefano Bastianello; Claudio Gasperini; N Tubridy; Tarek A Yousry; Maria Pia Sormani; B Viti; David H Miller; Massimo Filippi
Multiple sclerosis: interobserver agreement in reporting active lesions on serial brain MRI using conventional spin echo, fast spin echo, fast fluid-attenuated inversion recovery and post-contrast T1-weighted images.
Journal of neurology 1999;246(10):920-5.
1999: Maria Pia Sormani; P D Molyneux; Frederik Barkhof; David H Miller; Massimo Filippi
MRI enhancing lesion frequency from patients with MS enrolled in the placebo arms of clinical trials or in natural history studies.
Magnetic resonance imaging 1999;17(8):1236-7.
1999: Frederik Barkhof
MRI in multiple sclerosis: correlation with expanded disability status scale (EDSS).
Multiple sclerosis (Houndmills, Basingstoke, England) 1999;5(4):283-6.
1999: Aad Verrips; G J Nijeholt; Frederik Barkhof; B G M van Engelen; P Wesseling; JA Luyten; Ron A Wevers; J Stam; J H J Wokke; Lambert P van den Heuvel; A Keyser; Fons J M Gabreëls
Spinal xanthomatosis: a variant of cerebrotendinous xanthomatosis.
Brain : a journal of neurology 1999;122 ( Pt 8)():1589-95.
1999: Marianne A A van Walderveen; Frederik Barkhof; Petra J W Pouwels; Ronald A van Schijndel; Chris H Polman; Jonas A Castelijns
Neuronal damage in T1-hypointense multiple sclerosis lesions demonstrated in vivo using proton magnetic resonance spectroscopy.
Annals of neurology 1999;46(1):79-87.
1999: Anette H H van Boxel-Dezaire; S C Hoff; Bob W van Oosten; Cornelis L Verweij; A M Dräger; H J Adèr; Johannes C van Houwelingen; Frederik Barkhof; Chris H Polman; Lex Nagelkerken
Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis.
Annals of neurology 1999;45(6):695-703.
1999: Frederik Barkhof; Massimo Filippi; Jan-Hein T M van Waesberghe; A Campi; David H Miller; Herman J Adèr
Interobserver agreement for diagnostic MRI criteria in suspected multiple sclerosis.
Neuroradiology 1999;41(5):347-50.
1999: Maria Pia Sormani; PD Molyneux; Claudio Gasperini; Frederik Barkhof; Tarek A Yousry; David H Miller; Massimo Filippi
Statistical power of MRI monitored trials in multiple sclerosis: new data and comparison with previous results.
Journal of neurology, neurosurgery, and psychiatry 1999;66(4):465-9.
1999: Valerie L Stevenson; David H Miller; Marco Rovaris; Frederik Barkhof; B Brochet; V Dousset; V Dousset; Massimo Filippi; Xavier Montalban; Chris H Polman; Alex Rovira; J de Sa; Alan J Thompson
Primary and transitional progressive MS: a clinical and MRI cross-sectional study.
Neurology 1999;52(4):839-45.
1999: I Berry; Gareth Barker; Frederik Barkhof; A Campi; Vincent Dousset; JM Franconi; A Gass; W Schreiber; David H Miller; Paul S Tofts
A multicenter measurement of magnetization transfer ratio in normal white matter.
Journal of magnetic resonance imaging : JMRI 1999;9(3):441-6.
1999: Marianne A A van Walderveen; Luc Truyen; Bob W van Oosten; Jonas A Castelijns; Geert Lycklama à Nijeholt; Jan-Hein T M van Waesberghe; Chris H Polman; Frederik Barkhof
Development of hypointense lesions on T1-weighted spin-echo magnetic resonance images in multiple sclerosis: relation to inflammatory activity.
Archives of neurology 1999;56(3):345-51.
1999: Aad Verrips; Ron A Wevers; B G M van Engelen; A Keyser; B G Wolthers; Frederik Barkhof; A Stalenhoef; R De Graaf; F Janssen-Zijlstra; A Van Spreeken; Fons J M Gabreëls
Effect of simvastatin in addition to chenodeoxycholic acid in patients with cerebrotendinous xanthomatosis.
Metabolism: clinical and experimental 1999;48(2):233-8.
1999: Serge A R B Rombouts; Philip scheltens; W C Machielson; Frederik Barkhof; FG Hoogenraad; Dick J Veltman; Jakob Valk; Menno P Witter
Parametric fMRI analysis of visual encoding in the human medial temporal lobe.
Hippocampus 1999;9(6):637-43.
1999: Jan-Hein T M van Waesberghe; Frederik Barkhof
Magnetization transfer imaging of the spinal cord and the optic nerve in patients with multiple sclerosis.
Neurology 1999;53(5 Suppl 3):S46-8.
1998: Jan-Hein T M van Waesberghe; Mark A Van Buchem; Massimo Filippi; Jonas A Castelijns; M A Rocca; R van der Boom; Chris H Polman; Frederik Barkhof
MR outcome parameters in multiple sclerosis: comparison of surface-based thresholding segmentation and magnetization transfer ratio histographic analysis in relation to disability (a preliminary note).
AJNR. American journal of neuroradiology 1998;19(10):1857-62.
1998: Bob W van Oosten; Luc Truyen; Frederik Barkhof; Chris H Polman
Choosing drug therapy for multiple sclerosis. An update.
Drugs 1998;56(4):555-69.
1998: Marianne A A van Walderveen; Frederik Barkhof; MW Tas; Chris H Polman; S T Frequin; Otto R Hommes; A J Thompson; Jakob Valk
Patterns of brain magnetic resonance abnormalities on T2-weighted spin echo images in clinical subgroups of multiple sclerosis: a large cross-sectional study.
European neurology 1998;40(2):91-8.
1998: Serge A R B Rombouts; R H C Lazeron; Philip scheltens; Bernard Uitdehaag; M Sprenger; Jakob Valk; Frederik Barkhof
Visual activation patterns in patients with optic neuritis: an fMRI pilot study.
Neurology 1998;50(6):1896-9.
1998: Bob W van Oosten; Frederik Barkhof; Petra E T Scholten; B M von Blomberg; Herman J Adèr; Chris H Polman
Increased production of tumor necrosis factor alpha, and not of interferon gamma, preceding disease activity in patients with multiple sclerosis.
Archives of neurology 1998;55(6):793-8.
1998: Jan-Hein T M van Waesberghe; Jonas A Castelijns; R H C Lazeron; Geert Lycklama à Nijeholt; Frederik Barkhof
Magnetization transfer contrast (MTC) and long repetition time spin-echo MR imaging in multiple sclerosis.
Magnetic resonance imaging 1998;16(4):351-8.
1998: Frederik Barkhof; Joseph McGowan; Jan-Hein T M van Waesberghe; R I Grossman
Hypointense multiple sclerosis lesions on T1-weighted spin echo magnetic resonance images: their contribution in understanding multiple sclerosis evolution.
Journal of neurology, neurosurgery, and psychiatry 1998;64 Suppl 1():S77-9.
1998: Marianne A A van Walderveen; Wouter Kamphorst; Philip scheltens; Jan-Hein T M van Waesberghe; Rivka Ravid; Jakob Valk; Chris H Polman; Frederik Barkhof
Histopathologic correlate of hypointense lesions on T1-weighted spin-echo MRI in multiple sclerosis.
Neurology 1998;50(5):1282-8.
1998: G J Nijeholt; Marianne A A van Walderveen; Jonas A Castelijns; Jan-Hein T M van Waesberghe; Chris H Polman; Philip scheltens; Peter Rosier; Peter J H Jongen; Frederik Barkhof
Brain and spinal cord abnormalities in multiple sclerosis. Correlation between MRI parameters, clinical subtypes and symptoms.
Brain : a journal of neurology 1998;121 ( Pt 4)():687-97.
1998: Jan-Hein T M van Waesberghe; Marianne A A van Walderveen; Jonas A Castelijns; Philip scheltens; Geert Lycklama à Nijeholt; Chris H Polman; Frederik Barkhof
Patterns of lesion development in multiple sclerosis: longitudinal observations with T1-weighted spin-echo and magnetization transfer MR.
AJNR. American journal of neuroradiology 1998;19(4):675-83.
1998: Massimo Filippi; M A Horsfield; H J Adèr; Frederik Barkhof; P Bruzzi; A Evans; J A Frank; R I Grossman; Henry McFarland; Paul Molyneux; D W Paty; J Simon; P S Tofts; Jerry Wolinsky; David H Miller
Guidelines for using quantitative measures of brain magnetic resonance imaging abnormalities in monitoring the treatment of multiple sclerosis.
Annals of neurology 1998;43(4):499-506.
1998: Frederik Barkhof; Martin Elton; J Lindeboom; MW Tas; W F Schmidt; Otto R Hommes; Chris H Polman; A Kok; J Valk
Functional correlates of callosal atrophy in relapsing-remitting multiple sclerosis patients. A preliminary MRI study.
Journal of neurology 1998;245(3):153-8.
1998: PD Molyneux; Massimo Filippi; Frederik Barkhof; Claudio Gasperini; Tarek A Yousry; L Truyen; HM Lai; M A Rocca; Ivan Moseley; David H Miller
Correlations between monthly enhanced MRI lesion rate and changes in T2 lesion volume in multiple sclerosis.
Annals of neurology 1998;43(3):332-9.
1998: N Tubridy; Alasdair J Coles; Paul Molyneux; D A S Compston; Frederik Barkhof; Alan J Thompson; WI McDonald; David H Miller
Secondary progressive multiple sclerosis: the relationship between short-term MRI activity and clinical features.
Brain : a journal of neurology 1998;121 ( Pt 2)():225-31.
1998: Geert Lycklama à Nijeholt; Jonas A Castelijns; JG Weerts; Herman J Adèr; Jan-Hein T M van Waesberghe; Chris H Polman; Frederik Barkhof
Sagittal MR of multiple sclerosis in the spinal cord: fast versus conventional spin-echo imaging.
AJNR. American journal of neuroradiology 1998;19(2):355-60.
1998: S M Egeler-Peerdeman; Frederik Barkhof; R Walchenbach; Jakob Valk
Cine phase-contrast MR imaging in normal pressure hydrocephalus patients: relation to surgical outcome.
Acta neurochirurgica. Supplement 1998;71():340-2.
1998: Philip scheltens; T Erkinjunti; Didier LEYS; Lars-Olof Wahlund; Domenico Inzitari; T del Ser; Florence Pasquier; Frederik Barkhof; R Mäntylä; John V Bowler; Anders Wallin; J Ghika; Franz Fazekas; Leonardo Pantoni
White matter changes on CT and MRI: an overview of visual rating scales. European Task Force on Age-Related White Matter Changes.
European neurology 1998;39(2):80-9.
1998: Serge A R B Rombouts; Frederik Barkhof; FG Hoogenraad; M Sprenger; Philip scheltens
Within-subject reproducibility of visual activation patterns with functional magnetic resonance imaging using multislice echo planar imaging.
Magnetic resonance imaging 1998;16(2):105-13.
1998: Massimo Filippi; ML Gawne-Cain; Claudio Gasperini; J H vanWaesberghe; J Grimaud; Frederik Barkhof; Maria Pia Sormani; David H Miller
Effect of training and different measurement strategies on the reproducibility of brain MRI lesion load measurements in multiple sclerosis.
Neurology 1998;50(1):238-44.
1998: N Tubridy; H J Ader; Frederik Barkhof; Alan J Thompson; David H Miller
Exploratory treatment trials in multiple sclerosis using MRI: sample size calculations for relapsing-remitting and secondary progressive subgroups using placebo controlled parallel groups.
Journal of neurology, neurosurgery, and psychiatry 1998;64(1):50-5.
1997: Frederik Barkhof; Massimo Filippi; Jan-Hein T M van Waesberghe; Paul Molyneux; Marco Rovaris; Geert Lycklama à Nijeholt; N Tubridy; David H Miller; Tarek A Yousry; Ernst-Wilhelm Radue; Herman J Adèr
Improving interobserver variation in reporting gadolinium-enhanced MRI lesions in multiple sclerosis.
Neurology 1997;49(6):1682-8.
1997: Frederik Barkhof; Jan-Hein T M van Waesberghe; Bernard Uitdehaag; Chris H Polman
Ibuprofen does not suppress active multiple sclerosis lesions on gadolinium-enhanced MR images.
Annals of neurology 1997;42(6):982.
1997: Frederik Barkhof; Massimo Filippi; David H Miller; Philip scheltens; A Campi; Chris H Polman; G Comi; Herman J Adèr; N Losseff; J Valk
Comparison of MRI criteria at first presentation to predict conversion to clinically definite multiple sclerosis.
Brain : a journal of neurology 1997;120 ( Pt 11)():2059-69.
1997: Massimo Filippi; Frederik Barkhof; Bressi Sergio; Tarek A Yousry; David H Miller
Inter-rater variability in reporting enhancing lesions present on standard and triple dose gadolinium scans of patients with multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 1997;3(4):226-30.
1997: Serge A R B Rombouts; Frederik Barkhof; FG Hoogenraad; M Sprenger; Jakob Valk; Philip scheltens
Test-retest analysis with functional MR of the activated area in the human visual cortex.
AJNR. American journal of neuroradiology 1997;18(7):1317-22.
1997: Jan-Hein T M van Waesberghe; Jonas A Castelijns; W Roser; N Silver; Tarek A Yousry; Geert Lycklama à Nijeholt; Herman J Adèr; Bernard Uitdehaag; Ernst-Wilhelm Radue; Chris H Polman; Ludwig Kappos; David H Miller; Frederik Barkhof
Single-dose gadolinium with magnetization transfer versus triple-dose gadolinium in the MR detection of multiple sclerosis lesions.
AJNR. American journal of neuroradiology 1997;18(7):1279-85.
1997: Bob W van Oosten; Bernard Uitdehaag; Frederik Barkhof; H P Hartung; John Wagstaff; Chris H Polman
Interleukin-2 therapy does not exacerbate multiple sclerosis.
Neurology 1997;49(2):633-4.
1997: Massimo Filippi; Jan-Hein T M van Waesberghe; Mark A Horsfield; Bressi Sergio; Claudio Gasperini; Tarek A Yousry; ML Gawne-Cain; S P Morrissey; Maria A Rocca; Frederik Barkhof; Geert Lycklama à Nijeholt; Stefano Bastianello; David H Miller
Interscanner variation in brain MRI lesion load measurements in MS: implications for clinical trials.
Neurology 1997;49(2):371-7.
1997: Bob W van Oosten; M Lai; S Hodgkinson; Frederik Barkhof; D H Miller; I F Moseley; Alan J Thompson; P Rudge; A McDougall; J G McLeod; Herman J Adèr; Chris H Polman
Treatment of multiple sclerosis with the monoclonal anti-CD4 antibody cM-T412: results of a randomized, double-blind, placebo-controlled, MR-monitored phase II trial.
Neurology 1997;49(2):351-7.
1997: Geert Lycklama à Nijeholt; Frederik Barkhof; Philip scheltens; Jonas A Castelijns; Herman J Adèr; Jan-Hein T M van Waesberghe; Chris H Polman; S J Jongen; Jakob Valk
MR of the spinal cord in multiple sclerosis: relation to clinical subtype and disability.
AJNR. American journal of neuroradiology 1997;18(6):1041-8.
1997: Frederik Barkhof; Chris H Polman
Oral or intravenous methylprednisolone for acute relapses of MS?
Lancet 1997;349(9056):893-4.
1997: Frederik Barkhof; Massimo Filippi; David H Miller; P Tofts; L Kappos; A J Thompson
Strategies for optimizing MRI techniques aimed at monitoring disease activity in multiple sclerosis treatment trials.
Journal of neurology 1997;244(2):76-84.
1997: Serge A R B Rombouts; WC Machielsen; Menno P Witter; Frederik Barkhof; J Lindeboom; Philip scheltens
Visual association encoding activates the medial temporal lobe: a functional magnetic resonance imaging study.
Hippocampus 1997;7(6):594-601.
1997: Frederik Barkhof; M Smeets; P van der Valk; K E Tan; FG Hoogenraad; J Peeters; J Valk
MR imaging in retinoblastoma.
European radiology 1997;7(5):726-31.
1997: Jan-Hein T M van Waesberghe; Jonas A Castelijns; Philip scheltens; Luc Truyen; G J Lycklana A Nijeholt; FG Hoogenraad; Chris H Polman; Jakob Valk; Frederik Barkhof
Comparison of four potential MR parameters for severe tissue destruction in multiple sclerosis lesions.
Magnetic resonance imaging 1997;15(2):155-62.
1997: Martin J B Taphoorn; R A Potman; Frederik Barkhof; JG Weerts; Jakob Valk; A B Karim; Jan J Heimans
Quantitative computer-assisted analysis vs. visual estimation of MR imaging response of brain metastases to radiotherapy.
Magnetic resonance imaging 1997;15(1):99-106.
1997: Luc Truyen; Frederik Barkhof; MW Tas; Marianne A A van Walderveen; S T Frequin; Otto R Hommes; J J Nauta; Chris H Polman; J Valk
Specific power calculations for magnetic resonance imaging (MRI) in monitoring active relapsing-remitting multiple sclerosis (MS): implications for phase II therapeutic trials.
Multiple sclerosis (Houndmills, Basingstoke, England) 1997;2(6):283-90.
1997: Philip scheltens; Florence Pasquier; JG Weerts; Frederik Barkhof; Didier LEYS
Qualitative assessment of cerebral atrophy on MRI: inter- and intra-observer reproducibility in dementia and normal aging.
European neurology 1997;37(2):95-9.
1996: Serge A R B Rombouts; Frederik Barkhof; M Sprenger; J Valk; Philip scheltens
The functional basis of ocular dominance: functional MRI (fMRI) findings.
Neuroscience letters 1996;221(1):1-4.
1996: Bob W van Oosten; Frederik Barkhof; Luc Truyen; J B Boringa; Frits W Bertelsmann; B M von Blomberg; J N Woody; H P Hartung; Chris H Polman
Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2.
Neurology 1996;47(6):1531-4.
1996: Luc Truyen; Jan-Hein T M van Waesberghe; Marianne A A van Walderveen; Bob W van Oosten; Chris H Polman; Otto R Hommes; H J Adèr; Frederik Barkhof
Accumulation of hypointense lesions ("black holes") on T1 spin-echo MRI correlates with disease progression in multiple sclerosis.
Neurology 1996;47(6):1469-76.
1996: Geert Lycklama à Nijeholt; Frederik Barkhof; J A Castelijns; Jan-Hein T M van Waesberghe; J Valk; P J Jongen; Otto R Hommes
Comparison of two MR sequences for the detection of multiple sclerosis lesions in the spinal cord.
AJNR. American journal of neuroradiology 1996;17(8):1533-8.
1996: Bob W van Oosten; M Lai; Frederik Barkhof; D H Miller; I F Moseley; A J Thompson; S Hodgkinson; Chris H Polman
A phase II trial of anti-CD4 antibodies in the treatment of multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 1996;1(6):339-42.
1996: Otto R Hommes; Frederik Barkhof; P J Jongen; S T Frequin
Methylprednisolone treatment in multiple sclerosis: effect of treatment, pharmacokinetics, future.
Multiple sclerosis (Houndmills, Basingstoke, England) 1996;1(6):327-8.
1996: Luc Truyen; Frederik Barkhof; S T Frequin; Chris H Polman; H Tobi; Otto R Hommes; J Valk
Magnetic resonance imaging of epilepsy in multiple sclerosis: a case control study. Implications for treatment trials with 4-aminopyridine.
Multiple sclerosis (Houndmills, Basingstoke, England) 1996;1(4):213-7.
1996: Jan-Hein T M van Waesberghe; J A Castelijns; JG Weerts; G J Nijeholt; J P Hillegers; Chris H Polman; Frederik Barkhof
Disappearance of multiple sclerosis lesions with severely prolonged T1 on images obtained by a FLAIR pulse sequence.
Magnetic resonance imaging 1996;14(2):209-13.
1996: David H Miller; P S Albert; Frederik Barkhof; G Francis; J A Frank; S Hodgkinson; F D Lublin; Donald W Paty; Stephen C Reingold; J Simon
Guidelines for the use of magnetic resonance techniques in monitoring the treatment of multiple sclerosis. US National MS Society Task Force.
Annals of neurology 1996;39(1):6-16.
1995: Massimo Filippi; M A Horsfield; Paul S Tofts; Frederik Barkhof; A J Thompson; David H Miller
Quantitative assessment of MRI lesion load in monitoring the evolution of multiple sclerosis.
Brain : a journal of neurology 1995;118 ( Pt 6)():1601-12.
1995: Philip scheltens; Lenore J Launer; Frederik Barkhof; H C Weinstein; Willem A van Gool
Visual assessment of medial temporal lobe atrophy on magnetic resonance imaging: interobserver reliability.
Journal of neurology 1995;242(9):557-60.
1995: Marianne A A van Walderveen; Frederik Barkhof; Otto R Hommes; Chris H Polman; H Tobi; S T Frequin; J Valk
Correlating MRI and clinical disease activity in multiple sclerosis: relevance of hypointense lesions on short-TR/short-TE (T1-weighted) spin-echo images.
Neurology 1995;45(9):1684-90.
1995: Philip scheltens; Frederik Barkhof; D Leys; Erik C Wolters; Rivka Ravid; Wouter Kamphorst
Histopathologic correlates of white matter changes on MRI in Alzheimer's disease and normal aging.
Neurology 1995;45(5):883-8.
1995: Lenore J Launer; Philip scheltens; Jaap Lindeboom; Frederik Barkhof; H C Weinstein; Cees Jonker
Medial temporal lobe atrophy in an open population of very old persons: cognitive, brain atrophy, and sociomedical correlates.
Neurology 1995;45(4):747-52.
1995: Massimo Filippi; Donald W Paty; L Kappos; Frederik Barkhof; D A S Compston; Alan J Thompson; G J Zhao; C M Wiles; WI McDonald; David H Miller
Correlations between changes in disability and T2-weighted brain MRI activity in multiple sclerosis: a follow-up study.
Neurology 1995;45(2):255-60.
1995: Bob W van Oosten; Luc Truyen; Frederik Barkhof; Chris H Polman
Multiple sclerosis therapy. A practical guide.
Drugs 1995;49(2):200-12.
1995: C Baratti; Frederik Barkhof; F Hoogenraad; J Valk
Partially saturated fluid attenuated inversion recovery (FLAIR) sequences in multiple sclerosis: comparison with fully relaxed FLAIR and conventional spin-echo.
Magnetic resonance imaging 1995;13(4):513-21.
1994: S T Frequin; Karel J B Lamers; Frederik Barkhof; G F Borm; Otto R Hommes
Follow-up study of MS patients treated with high-dose intravenous methylprednisolone.
Acta neurologica Scandinavica 1994;90(2):105-10.
1994: Frederik Barkhof; M W Tas; S T Frequin; Philip scheltens; Otto R Hommes; J J Nauta; J Valk
Limited duration of the effect of methylprednisolone on changes on MRI in multiple sclerosis.
Neuroradiology 1994;36(5):382-7.
1994: Frederik Barkhof; M Kouwenhoven; Philip scheltens; M Sprenger; P Algra; J Valk
Phase-contrast cine MR imaging of normal aqueductal CSF flow. Effect of aging and relation to CSF void on modulus MR.
Acta radiologica (Stockholm, Sweden : 1987) 1994;35(2):123-30.
1994: Marianne A A van Walderveen; M W Tas; Frederik Barkhof; Chris H Polman; S T Frequin; Otto R Hommes; J Valk
Magnetic resonance evaluation of disease activity during pregnancy in multiple sclerosis.
Neurology 1994;44(2):327-9.
1994: E J Zijlstra; Martin J B Taphoorn; Frederik Barkhof; F G Hoogenraad; Jan J Heimans; J Valk
Radiotherapy response of cerebral metastases quantified by serial MR imaging.
Journal of neuro-oncology 1994;21(2):171-6.
1993: David H Miller; Frederik Barkhof; J J Nauta
Gadolinium enhancement increases the sensitivity of MRI in detecting disease activity in multiple sclerosis.
Brain : a journal of neurology 1993;116 ( Pt 5)():1077-94.
1993: S T Frequin; Karel J B Lamers; G F Borm; Frederik Barkhof; P J Jongen; Otto R Hommes
T-cell subsets in the cerebrospinal fluid and peripheral blood of multiple sclerosis patients treated with high-dose intravenous methylprednisolone.
Acta neurologica Scandinavica 1993;88(2):80-6.
1993: S T Frequin; R A Wevers; M Braam; Frederik Barkhof; Otto R Hommes
Decreased vitamin B12 and folate levels in cerebrospinal fluid and serum of multiple sclerosis patients after high-dose intravenous methylprednisolone.
Journal of neurology 1993;240(5):305-8.
1993: Frederik Barkhof; A J Thompson; L Kappos; J J Nauta; T Yousri; I Berry; G Scotti; B Appel; P S Tofts; D H Miller
Database for serial magnetic resonance imaging in multiple sclerosis.
Neuroradiology 1993;35(5):362-6.
1992: Frederik Barkhof; Philip scheltens; S T Frequin; J J Nauta; M W Tas; J Valk; Otto R Hommes
Relapsing-remitting multiple sclerosis: sequential enhanced MR imaging vs clinical findings in determining disease activity.
AJR. American journal of roentgenology 1992;159(5):1041-7.
1992: S T Frequin; Frederik Barkhof; Karel J B Lamers; Otto R Hommes
The effects of high-dose methylprednisolone on gadolinium-enhanced magnetic resonance imaging and cerebrospinal fluid measurements in multiple sclerosis.
Journal of neuroimmunology 1992;40(2-3):265-72.
1992: S T Frequin; Frederik Barkhof; Karel J B Lamers; Otto R Hommes; G F Borm
CSF myelin basic protein, IgG and IgM levels in 101 MS patients before and after treatment with high-dose intravenous methylprednisolone.
Acta neurologica Scandinavica 1992;86(3):291-7.
1992: Frederik Barkhof; J Valk; Otto R Hommes; Philip scheltens; J J Nauta
Gadopentetate dimeglumine enhancement of multiple sclerosis lesions on long TR spin-echo images at 0.6 T.
AJNR. American journal of neuroradiology 1992;13(4):1257-9.
1992: Philip scheltens; Frederik Barkhof; J Valk; P R Algra; R G van der Hoop; J Nauta; Erik C Wolters
White matter lesions on magnetic resonance imaging in clinically diagnosed Alzheimer's disease. Evidence for heterogeneity.
Brain : a journal of neurology 1992;115 ( Pt 3)():735-48.
1992: Frederik Barkhof; J Valk; Otto R Hommes; Philip scheltens
Meningeal Gd-DTPA enhancement in multiple sclerosis.
AJNR. American journal of neuroradiology 1992;13(1):397-400.
1992: Frederik Barkhof; S T Frequin; Otto R Hommes; Karel J B Lamers; Philip scheltens; W J van Geel; J Valk
A correlative triad of gadolinium-DTPA MRI, EDSS, and CSF-MBP in relapsing multiple sclerosis patients treated with high-dose intravenous methylprednisolone.
Neurology 1992;42(1):63-7.
1991: David H Miller; Frederik Barkhof; I Berry; L Kappos; G Scotti; Alan J Thompson
Magnetic resonance imaging in monitoring the treatment of multiple sclerosis: concerted action guidelines.
Journal of neurology, neurosurgery, and psychiatry 1991;54(8):683-8.
1991: Frederik Barkhof; Otto R Hommes; Philip scheltens; J Valk
Quantitative MRI changes in gadolinium-DTPA enhancement after high-dose intravenous methylprednisolone in multiple sclerosis.
Neurology 1991;41(8):1219-22.
1991: Frederik Barkhof; Philip scheltens; J Valk; C Waalewijn; Bernard Uitdehaag; Chris H Polman
Serial quantitative MR assessment of optic neuritis in a case of neuromyelitis optica, using Gadolinium- "enhanced" STIR imaging.
Neuroradiology 1991;33(1):70-1.