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Pinpin Lin

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Po-Hung Chen; Lih-Ann Li; Mei-Ya Shen; Hui-Ti Tsai; Jinghua Tsai Chang; Pinpin Lin
Aryl hydrocarbon receptor is a target of 17-Allylamino-17-demethoxygeldanamycin and enhances its anticancer activity in lung adenocarcinoma cells.
Chia-Chi Ho; Han Chang; Yong-Chien Ling; Hui-Ti Tsai; Ming-Hsien Tsai; Chung-Shi Yang; Pinpin Lin
Quantum dot 705, a cadmium-based nanoparticle, induces persistent inflammation and granuloma formation in the mouse lung.
Chia-Chang Wu; Chi-Jung Chung; Chao-Yuan Huang; Hui-Ling Lee; Pinpin Lin; Yeong-Shiau Pu; Chien-Tien Su; Yu-Mei Hsueh
Joint effect of arsenic methylation profile and NNK metabolites on urothelial carcinoma.

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All Publications

2013: Po-Hung Chen; Lih-Ann Li; Mei-Ya Shen; Hui-Ti Tsai; Jinghua Tsai Chang; Pinpin Lin
Aryl hydrocarbon receptor is a target of 17-Allylamino-17-demethoxygeldanamycin and enhances its anticancer activity in lung adenocarcinoma cells.
Molecular pharmacology 2013;83(3):605-12.
2013: Chia-Chi Ho; Han Chang; Yong-Chien Ling; Hui-Ti Tsai; Ming-Hsien Tsai; Chung-Shi Yang; Pinpin Lin
Quantum dot 705, a cadmium-based nanoparticle, induces persistent inflammation and granuloma formation in the mouse lung.
Nanotoxicology 2013;7(1):105-15.
2012: Chia-Chang Wu; Chi-Jung Chung; Chao-Yuan Huang; Hui-Ling Lee; Pinpin Lin; Yeong-Shiau Pu; Chien-Tien Su; Yu-Mei Hsueh
Joint effect of arsenic methylation profile and NNK metabolites on urothelial carcinoma.
The Journal of urology 2012;188(5):1701-5.
2012: Ya-Hsin Cheng; Chein-Hui Hung; Lih-Ann Li; Nai Wen Chang; Li-Chuan Cheng; Pinpin Lin; Chingju Lin
Baicalein induces G1 arrest in oral cancer cells by enhancing the degradation of cyclin D1 and activating AhR to decrease Rb phosphorylation.
Toxicology and applied pharmacology 2012;263(3):360-7.
2012: Chien-Kai Wang; Ming-Hsien Tsai; Han Chang; Yu-Chun Kuo; Hui-Ling Lee; Pinpin Lin
Enhancement between environmental tobacco smoke and arsenic on emphysema-like lesions in mice.
Journal of hazardous materials 2012;221-222():256-63.
2012: Mo-Hsiung Yang; Louis W Chang; Chia-Hua Lin; Pinpin Lin
Application of ICP-MS for the study of disposition and toxicity of metal-based nanomaterials.
Methods in molecular biology (Clifton, N.J.) 2012;926():345-59.
2011: Chia-Hua Lin; Han Chang; Louis W Chang; Wan-Hsuan Chang; Ming-Hsien Tsai; Chien-Jen Wang; Chung-Shi Yang; Mo-Hsiung Yang; Pinpin Lin
Cd/Se/Te-based quantum dot 705 modulated redox homeostasis with hepatotoxicity in mice.
Nanotoxicology 2011;5(4):650-63.
2011: Chi-Jung Chung; Hui-Ling Lee; Hsiu-Yuan Yang; Pinpin Lin; Yeong-Shiau Pu; Horng-Sheng Shiue; Chien-Tien Su; Yu-Mei Hsueh
Low ratio of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol-glucuronides (NNAL-Gluc)/free NNAL increases urothelial carcinoma risk.
The Science of the total environment 2011;409(9):1638-42.
2010: Shun-Chieh Young; Louis W Chang; Hui-Ling Lee; Lung-Hung Tsai; Yin-Chang Liu; Pinpin Lin
DNA damages induced by trans, trans-2,4-decadienal (tt-DDE), a component of cooking oil fume, in human bronchial epithelial cells.
Environmental and molecular mutagenesis 2010;51(4):315-21.
2010: Wei-Ting Liao; Hsin-Su Yu; Pinpin Lin; Louis W Chang
Arsenite promotes centrosome abnormalities under a p53 compromised status induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
Toxicology and applied pharmacology 2010;243(1):55-62.
2009: Chien-Kai Wang; Han Chang; Po-Hung Chen; Jinghua Tsai Chang; Yu-Chun Kuo; Jiunn-Liang Ko; Pinpin Lin
Aryl hydrocarbon receptor activation and overexpression upregulated fibroblast growth factor-9 in human lung adenocarcinomas.
International journal of cancer. Journal international du cancer 2009;125(4):807-15.
2009: Hsien-Tsung Yao; Pinpin Lin; Yi-Wei Chang; Chiung-Tong Chen; Meng-Tsan Chiang; Ling Chang; Yu-Chun Kuo; Hui-Ti Tsai; Teng-Kuang Yeh
Effect of taurine supplementation on cytochrome P450 2E1 and oxidative stress in the liver and kidneys of rats with streptozotocin-induced diabetes.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2009;47(7):1703-9.
2009: Chia-Hua Lin; Louis W Chang; Han Chang; Mo-Hsiung Yang; Chung-Shi Yang; Wan-Hau Lai; Wan-Hsuan Chang; Pinpin Lin
The chemical fate of the Cd/Se/Te-based quantum dot 705 in the biological system: toxicity implications.
Nanotechnology 2009;20(21):215101.
2009: Michele Cote; Wei Chen; Daryn W Smith; Simone Benhamou; Christine Bouchardy; Dorota Butkiewicz; Kwun M Fong; Manuel Gené; Ari Hirvonen; Chikako Kiyohara; Jill E Larsen; Pinpin Lin; Ole Raaschou-Nielsen; Andrew C Povey; Edyta Reszka; Angela Risch; Joachim Schneider; Ann Grossbart Schwartz; Mette Sorensen; Jordi To-Figueras; Shinkan Tokudome; Yuepu Pu; Ping Yang; Angela S Wenzlaff; Harriet Wikman; Emanuela Taioli
Meta- and pooled analysis of GSTP1 polymorphism and lung cancer: a HuGE-GSEC review.
American journal of epidemiology 2009;169(7):802-14.
2009: Jang-Ming Su; Pinpin Lin; Chien-Kai Wang; Han Chang
Overexpression of cytochrome P450 1B1 in advanced non-small cell lung cancer: a potential therapeutic target.
Anticancer research 2009;29(2):509-15.
2009: Jui-Pin Wu; Louis W Chang; Hsien-Tsung Yao; Han Chang; Hui-Ti Tsai; Ming-Hsien Tsai; Teng-Kuang Yeh; Pinpin Lin
Involvement of oxidative stress and activation of aryl hydrocarbon receptor in elevation of CYP1A1 expression and activity in lung cells and tissues by arsenic: an in vitro and in vivo study.
Toxicological sciences : an official journal of the Society of Toxicology 2009;107(2):385-93.
2008: Hui-Ling Lee; Yu-Mei Hsueh; Chi-Jung Chung; Yeong-Shiau Pu; Louis W Chang; Dennis Paul Hsientang Hsieh; Saou-Hsing Liou; Pinpin Lin
Correlation between the urine profile of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolites and N7-methylguanine in urothelial carcinoma patients.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(12):3390-5.
2008: Suh-Woan Hu; Pinpin Lin; Chun-Chieh Chen
Association of cytochrome P450 1B1 gene expression in peripheral leukocytes with blood lipid levels in waste incinerator workers.
Annals of epidemiology 2008;18(10):784-91.
2008: Pinpin Lin; Jein-Wen Chen; Louis W Chang; Jui-Pin Wu; Laurel Redding; Han Chang; Teng-Kuang Yeh; Chung Shi Yang; Ming-Hsien Tsai; Hsiu-Jen Wang; Yu-Chun Kuo; Raymond S H Yang
Computational and ultrastructural toxicology of a nanoparticle, Quantum Dot 705, in mice.
Environmental science & technology 2008;42(16):6264-70.
2008: Chia-Chi Ho; Yong-Chien Ling; Louis W Chang; Hui-Ti Tsai; Ming-Hsien Tsai; Pinpin Lin
17-Beta estradiol and hydroxyestradiols interact via the NF-kappa B pathway to elevate cyclooxygenase 2 expression and prostaglandin E2 secretion in human bronchial epithelial cells.
Toxicological sciences : an official journal of the Society of Toxicology 2008;104(2):294-302.
2008: Kyoung-Mu Lee; Daehee Kang; Margie L Clapper; Magnus Ingelman-Sundberg; Masko Ono-Kihara; Chikako Kiyohara; Shen Min; Qing Lan; Loïc Le Marchand; Pinpin Lin; Maria Li Lung; Hatice Pinarbasi; Paola Pisani; Petcharin Srivatanakul; Adeline Seow; Haruhiko Sugimura; Shinkan Tokudome; Jun Yokota; Emanuela Taioli
CYP1A1, GSTM1, and GSTT1 polymorphisms, smoking, and lung cancer risk in a pooled analysis among Asian populations.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(5):1120-6.
2008: Yun-Ching Chang; Pinpin Lin
Trans, trans-2,4-decadienal induced cell proliferation via p27 pathway in human bronchial epithelial cells.
Toxicology and applied pharmacology 2008;228(1):76-83.
2008: Hui-Ling Lee; Louis W Chang; Jui-Pin Wu; Yune-Fang Ueng; Ming-Hsien Tsai; Dennis P H Hsieh; Pinpin Lin
Enhancements of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism and carcinogenic risk via NNK/arsenic interaction.
Toxicology and applied pharmacology 2008;227(1):108-14.
2007: Wei-Ting Liao; Pinpin Lin; Tai-Shan Cheng; Hsin-Su Yu; Louis W Chang
Arsenic promotes centrosome abnormalities and cell colony formation in p53 compromised human lung cells.
Toxicology and applied pharmacology 2007;225(2):162-70.
2007: Raymond S H Yang; Louis W Chang; Jui-Pin Wu; Ming-Hsien Tsai; Hsiu-Jen Wang; Yu-Chun Kuo; Teng-Kuang Yeh; Chung Shi Yang; Pinpin Lin
Persistent tissue kinetics and redistribution of nanoparticles, quantum dot 705, in mice: ICP-MS quantitative assessment.
Environmental health perspectives 2007;115(9):1339-43.
2007: Po-Hsiung Lin; Chia-Hua Lin; Chuan-Chen Huang; Ming-Chien Chuang; Pinpin Lin
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces oxidative stress, DNA strand breaks, and poly(ADP-ribose) polymerase-1 activation in human breast carcinoma cell lines.
Toxicology letters 2007;172(3):146-58.
2007: Louis W Chang; Yun-Ching Chang; Chia-Chi Ho; Ming-Hsien Tsai; Pinpin Lin
Increase of carcinogenic risk via enhancement of cyclooxygenase-2 expression and hydroxyestradiol accumulation in human lung cells as a result of interaction between BaP and 17-beta estradiol.
Carcinogenesis 2007;28(7):1606-12.
2007: Yahsin Cheng; Louis W Chang; Li-Chuan Cheng; Ming-Hsien Tsai; Pinpin Lin
4-Methoxyestradiol-induced oxidative injuries in human lung epithelial cells.
Toxicology and applied pharmacology 2007;220(3):271-7.
2007: Jinghua Tsai Chang; Han Chang; Po-Hung Chen; Shong-Ling Lin; Pinpin Lin
Requirement of aryl hydrocarbon receptor overexpression for CYP1B1 up-regulation and cell growth in human lung adenocarcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(1):38-45.
2007: Sheng-Yen Lin; Yi-Torng Tee; Soo-Cheen Ng; Han Chang; Pinpin Lin; Gin-Den Chen
Changes in the extracellular matrix in the anterior vagina of women with or without prolapse.
International urogynecology journal and pelvic floor dysfunction 2007;18(1):43-8.
2006: Suh-Woan Hu; Chun-Chieh Chen; Chung-Yih Kuo; Wen-Hai Lin; Pinpin Lin
Increased cytochrome P4501B1 gene expression in peripheral leukocytes of municipal waste incinerator workers.
Toxicology letters 2006;160(2):112-20.
2006: Han Chang; Louis W Chang; Ya-Hsin Cheng; Wen-Tien Tsai; Ming-Xian Tsai; Pinpin Lin
Preferential induction of CYP1A1 and CYP1B1 in CCSP-positive cells.
Toxicological sciences : an official journal of the Society of Toxicology 2006;89(1):205-13.
2005: Louis W Chang; Wai-Sze Lo; Pinpin Lin
Trans, trans-2,4-decadienal, a product found in cooking oil fumes, induces cell proliferation and cytokine production due to reactive oxygen species in human bronchial epithelial cells.
Toxicological sciences : an official journal of the Society of Toxicology 2005;87(2):337-43.
2005: H Chang; Ying-Jan Wang; Louis W Chang; Pinpin Lin
A histochemical and pathological study on the interrelationship between TCDD-induced AhR expression, AhR activation, and hepatotoxicity in mice.
Journal of toxicology and environmental health. Part A 2005;68(17-18):1567-79.
2005: Yu-Mei Hsueh; Pinpin Lin; Hui-Wen Chen; Horng-Sheng Shiue; Chi-Jung Chung; Chiao-Tzu Tsai; Yung-Kay Huang; Hung-Yi Chiou; Chien-Jen Chen
Genetic polymorphisms of oxidative and antioxidant enzymes and arsenic-related hypertension.
Journal of toxicology and environmental health. Part A 2005;68(17-18):1471-84.
2005: Han Chang; Jang-Ming Su; Chee C Huang; Lan C Liu; Chung H Tsai; Ming-Chih Chou; Pinpin Lin
Using a combination of cytochrome P450 1B1 and beta-catenin for early diagnosis and prevention of colorectal cancer.
Cancer detection and prevention 2005;29(6):562-9.
2004: Shih-Yin Chen; Jane-Ru Vivan Lin; Ramalakshmi Darbha; Pinpin Lin; Tsung-Yun Liu; Yi-Ming Arthur Chen
Glycine N-methyltransferase tumor susceptibility gene in the benzo(a)pyrene-detoxification pathway.
Cancer research 2004;64(10):3617-23.
2004: Ming-Fang Wu; Wen-Jun Wu; Gee-Chen Chang; Chin-Yi Chen; Suh-Woan Hu; Wen-Tien Tsai; Huei Lee; Pinpin Lin
Increased expression of cytochrome P4501B1 in peripheral leukocytes from lung cancer patients.
Toxicology letters 2004;150(2):211-9.
2004: Pinpin Lin; Jinghua Tsai Chang; Jiunn-Liang Ko; Sheng-Hung Liao; Wai-Sze Lo
Reduction of androgen receptor expression by benzo[alpha]pyrene and 7,8-dihydro-9,10-epoxy-7,8,9,10-tetrahydrobenzo[alpha]pyrene in human lung cells.
Biochemical pharmacology 2004;67(8):1523-30.
2004: Pinpin Lin; Yu-Chen Chang; Chien-Hsun Chen; Wen-Jyh Yang; Ya-Hsin Cheng; Louis W Chang
A comparative study on the effects of 2,3,7,8,-tetrachlorodibenzo-p-dioxin polychlorinated biphenyl126 and estrogen in human bronchial epithelial cells.
Toxicology and applied pharmacology 2004;195(1):83-91.
2003: Pinpin Lin; Han Chang; William L Ho; Meng-Hsiang Wu; Jang-Ming Su
Association of aryl hydrocarbon receptor and cytochrome P4501B1 expressions in human non-small cell lung cancers.
Lung cancer (Amsterdam, Netherlands) 2003;42(3):255-61.
2003: Tzu-Chin Wu; Pinpin Lin; Chung-Ping Hsu; Yi-Jie Huang; Chih-Yi Chen; Wen-Chuan Chung; Huei Lee; Jiunn-Liang Ko
Loss of telomerase activity may be a potential favorable prognostic marker in lung carcinomas.
Lung cancer (Amsterdam, Netherlands) 2003;41(2):163-9.
2003: Pinpin Lin; Yu-Mei Hsueh; Jiunn-Liang Ko; Yu-Fei Liang; Kan-Jen Tsai; Chih-Yi Chen
Analysis of NQO1, GSTP1, and MnSOD genetic polymorphisms on lung cancer risk in Taiwan.
Lung cancer (Amsterdam, Netherlands) 2003;40(2):123-9.
2003: Pinpin Lin; Han Chang; Wen-Tien Tsai; Meng-Hsiang Wu; Yung-Shen Liao; Jung-Ta Chen; Jang-Ming Su
Overexpression of aryl hydrocarbon receptor in human lung carcinomas.
Toxicologic pathology 2003;31(1):22-30.
2003: Pinpin Lin; Suh-Woan Hu; Tzu-Hua Chang
Correlation between gene expression of aryl hydrocarbon receptor (AhR), hydrocarbon receptor nuclear translocator (Arnt), cytochromes P4501A1 (CYP1A1) and 1B1 (CYP1B1), and inducibility of CYP1A1 and CYP1B1 in human lymphocytes.
Toxicological sciences : an official journal of the Society of Toxicology 2003;71(1):20-6.
2002: Jiunn-Liang Ko; Ming-Chiang Chiao; Shu-Lin Chang; Pinpin Lin; Jin-Ching Lin; Gwo-Tarng Sheu; Huei Lee
A novel p53 mutant retained functional activity in lung carcinomas.
DNA repair 2002;1(9):755-62.
2001: Y H Tung; J L Ko; Y F Liang; L Yin; Y Pu; Pinpin Lin
Cooking oil fume-induced cytokine expression and oxidative stress in human lung epithelial cells.
Environmental research 2001;87(1):47-54.
2000: Pinpin Lin; S L Wang; HJ Wang; K W Chen; H S Lee; Kan-Jen Tsai; Chih-Yi Chen; H Lee
Association of CYP1A1 and microsomal epoxide hydrolase polymorphisms with lung squamous cell carcinoma.
British journal of cancer 2000;82(4):852-7.
1999: Pinpin Lin; HJ Wang; H Lee; H S Lee; S L Wang; Y M Hsueh; Kan-Jen Tsai; Chih-Yi Chen
NAD(P)H: quinone oxidoreductase polymorphism and lung cancer in Taiwan.
Journal of toxicology and environmental health. Part A 1999;58(4):187-97.
1999: S L Wang; H Lee; K W Chen; Kan-Jen Tsai; Chih-Yi Chen; Pinpin Lin
Cytochrome P4502E1 genetic polymorphisms and lung cancer in a Taiwanese population.
Lung cancer (Amsterdam, Netherlands) 1999;26(1):27-34.
1999: K W Chang; H Lee; HJ Wang; S Y Chen; Pinpin Lin
Differential response to benzo[A]pyrene in human lung adenocarcinoma cell lines: the absence of aryl hydrocarbon receptor activation.
Life sciences 1999;65(13):1339-49.