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Song Lin

Research Profile

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Publications

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Patrick C Reid; Song Lin; marie T vanier; Yoshiko Ohno-Iwashita; H James Harwood; William F Hickey; Catherine C Y Chang; Ta-Yuan Chang
Partial blockage of sterol biosynthesis with a squalene synthase inhibitor in early postnatal Niemann-Pick type C npcnih null mice brains reduces neuronal cholesterol accumulation, abrogates astrogliosis, but may inhibit myelin maturation.
Shigeki Sugii; Song Lin; Nobutaka Ohgami; Masato Ohashi; Catherine C Y Chang; Ta-Yuan Chang
Roles of endogenously synthesized sterols in the endocytic pathway.
Zhan-Yun Guo; Song Lin; Jennifer A Heinen; Catherine C Y Chang; Ta-Yuan Chang
The active site His-460 of human acyl-coenzyme A:cholesterol acyltransferase 1 resides in a hitherto undisclosed transmembrane domain.

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All Publications

2008: Patrick C Reid; Song Lin; marie T vanier; Yoshiko Ohno-Iwashita; H James Harwood; William F Hickey; Catherine C Y Chang; Ta-Yuan Chang
Partial blockage of sterol biosynthesis with a squalene synthase inhibitor in early postnatal Niemann-Pick type C npcnih null mice brains reduces neuronal cholesterol accumulation, abrogates astrogliosis, but may inhibit myelin maturation.
Journal of neuroscience methods 2008;168(1):15-25.
2006: Shigeki Sugii; Song Lin; Nobutaka Ohgami; Masato Ohashi; Catherine C Y Chang; Ta-Yuan Chang
Roles of endogenously synthesized sterols in the endocytic pathway.
The Journal of biological chemistry 2006;281(32):23191-206.
2005: Zhan-Yun Guo; Song Lin; Jennifer A Heinen; Catherine C Y Chang; Ta-Yuan Chang
The active site His-460 of human acyl-coenzyme A:cholesterol acyltransferase 1 resides in a hitherto undisclosed transmembrane domain.
The Journal of biological chemistry 2005;280(45):37814-26.
2003: Song Lin; Xiaohui Lu; Catherine C Y Chang; Ta-Yuan Chang
Human acyl-coenzyme A:cholesterol acyltransferase expressed in chinese hamster ovary cells: membrane topology and active site location.
Molecular biology of the cell 2003;14(6):2447-60.
2002: Xiaohui Lu; Song Lin; Catherine C Y Chang; Ta-Yuan Chang
Mutant acyl-coenzyme A:cholesterol acyltransferase 1 devoid of cysteine residues remains catalytically active.
The Journal of biological chemistry 2002;277(1):711-8.
2001: Ta-Yuan Chang; Catherine C Y Chang; Xiaohui Lu; Song Lin
Catalysis of ACAT may be completed within the plane of the membrane: a working hypothesis.
Journal of lipid research 2001;42(12):1933-8.
2001: Ta-Yuan Chang; Catherine C Y Chang; Song Lin; CHUNJIANG YU; Bo-Liang Li; Akira Miyazaki
Roles of acyl-coenzyme A:cholesterol acyltransferase-1 and -2.
Current opinion in lipidology 2001;12(3):289-96.
2000: Catherine C Y Chang; Naomi Sakashita; Kim Ornvold; Oneil Lee; ET Chang; Ruhong Dong; Song Lin; C Y Lee; Stephen C Strom; R Kashyap; J J Fung; R V Farese; Jean-François Patoiseau; André Delhon; Ta-Yuan Chang
Immunological quantitation and localization of ACAT-1 and ACAT-2 in human liver and small intestine.
The Journal of biological chemistry 2000;275(36):28083-92.
1999: CHUNJIANG YU; Jun Chen; Song Lin; Jay Liu; Catherine C Y Chang; Ta-Yuan Chang
Human acyl-CoA:cholesterol acyltransferase-1 is a homotetrameric enzyme in intact cells and in vitro.
The Journal of biological chemistry 1999;274(51):36139-45.
1999: Song Lin; D Cheng; M S Liu; Jun Chen; Ta-Yuan Chang
Human acyl-CoA:cholesterol acyltransferase-1 in the endoplasmic reticulum contains seven transmembrane domains.
The Journal of biological chemistry 1999;274(33):23276-85.
1999: Bo-Liang Li; X L Li; Z J Duan; Oneil Lee; Song Lin; Z M Ma; Catherine C Y Chang; Xin-Ying Yang; Jonathan P Park; Thuluvancheri K Mohandas; Walter W Noll; L Chan; Ta-Yuan Chang
Human acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) gene organization and evidence that the 4.3-kilobase ACAT-1 mRNA is produced from two different chromosomes.
The Journal of biological chemistry 1999;274(16):11060-71.