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Sami Barmada

Research Profile

Chemicals & Drugs

Living Beings

Physiology

Mutation

Disorders

Anatomy

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Publications

TOP 3
Andrea Serio; Christopher E Shaw; Carole Shum; Rick Siller; David Story; Ian Wilmut; Chen Zhao; Dale Michael Ando; Sami J Barmada; Bilada Bilican; Karen Burr; Monica A Carrasco; Steven Finkbeiner; Ghazal Haghi; Tom Maniatis; Agnes Lumi Nishimura; Hemali P Phatnani; Siddharthan Chandran
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy.
Maria Armakola; Sami J Barmada; Zamia Diaz; Xiaodong Fang; Robert V Farese; Matthew D Figley; Steven Finkbeiner; Matthew J Higgins; Nevan J Krogan; Emily A Scarborough; James Shorter; Aaron D Gitler
Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models.
Lauren Herl Martens; Sang-Won Min; Binggui Sun; Jiasheng Zhang; Ping Zhou; Steven Finkbeiner; Li Gan; Eric J Huang; Sherry Kamiya; Sami J Barmada; Robert V Farese
Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.

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All Publications

2013: Andrea Serio; Christopher E Shaw; Carole Shum; Rick Siller; David Story; Ian Wilmut; Chen Zhao; Dale Michael Ando; Sami J Barmada; Bilada Bilican; Karen Burr; Monica A Carrasco; Steven Finkbeiner; Ghazal Haghi; Tom Maniatis; Agnes Lumi Nishimura; Hemali P Phatnani; Siddharthan Chandran
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(12):4697-702.
2012: Maria Armakola; Sami J Barmada; Zamia Diaz; Xiaodong Fang; Robert V Farese; Matthew D Figley; Steven Finkbeiner; Matthew J Higgins; Nevan J Krogan; Emily A Scarborough; James Shorter; Aaron D Gitler
Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models.
Nature genetics 2012;44(12):1302-9.
2012: Lauren Herl Martens; Sang-Won Min; Binggui Sun; Jiasheng Zhang; Ping Zhou; Steven Finkbeiner; Li Gan; Eric J Huang; Sherry Kamiya; Sami J Barmada; Robert V Farese
Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.
The Journal of clinical investigation 2012;122(11):3955-9.
2012: Maggie W Waung; Sami J Barmada; William P Dillon; Aaron W Grossman; S Andrew Josephson; Jeffrey W Ralph
Pearls & Oy-sters: the use of CT venography in Hirayama disease.
Neurology 2012;79(5):e38-40.
2012: Bilada Bilican; Monica Carrasco; Sami J Barmada; George Q Daley; Steven Finkbeiner; Judy Fletcher; Brad A Friedman; Giles E Hardingham; Tom Maniatis; Agnes Lumi Nishimura; In-Hyun Park; Hemali P Phatnani; Clare A Puddifoot; Andrea Serio; Christopher E Shaw; David Story; Gareth J Sullivan; Ian Wilmut; David J A Wyllie; Siddharthan Chandran
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(15):5803-8.
2010: Sami J Barmada; Gaia Skibinski; Erica Korb; Elizabeth J Rao; Jane Y Wu; Steven Finkbeiner
Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(2):639-49.
2010: Sami J Barmada; Steven Finkbeiner
Pathogenic TARDBP mutations in amyotrophic lateral sclerosis and frontotemporal dementia: disease-associated pathways.
Reviews in the neurosciences 2010;21(4):251-72.
2009: Martin Jeffrey; Caroline M Goodsir; Gillian McGovern; Sami J Barmada; Andrea Z Medrano; David A Harris
Prion protein with an insertional mutation accumulates on axonal and dendritic plasmalemma and is associated with distinctive ultrastructural changes.
The American journal of pathology 2009;175(3):1208-17.
2008: Andrea Z Medrano; Sami J Barmada; Emiliano Biasini; David A Harris
GFP-tagged mutant prion protein forms intra-axonal aggregates in transgenic mice.
Neurobiology of disease 2008;31(1):20-32.
2007: Aimin Li; Pedro Piccardo; Sami J Barmada; Bernardino Ghetti; David A Harris
Prion protein with an octapeptide insertion has impaired neuroprotective activity in transgenic mice.
The EMBO journal 2007;26(11):2777-85.
2007: Nathaniel J Szewczyk; Brant K Peterson; Sami J Barmada; Leah P Parkinson; Lewis A Jacobson
Opposed growth factor signals control protein degradation in muscles of Caenorhabditis elegans.
The EMBO journal 2007;26(4):935-43.
2007: Aimin Li; Sami J Barmada; Kevin A Roth; David A Harris
N-terminally deleted forms of the prion protein activate both Bax-dependent and Bax-independent neurotoxic pathways.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(4):852-9.
2005: Sami J Barmada; David A Harris
Visualization of prion infection in transgenic mice expressing green fluorescent protein-tagged prion protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(24):5824-32.
2004: Sami J Barmada; Pedro Piccardo; Keiji Yamaguchi; Bernardino Ghetti; David A Harris
GFP-tagged prion protein is correctly localized and functionally active in the brains of transgenic mice.
Neurobiology of disease 2004;16(3):527-37.
2001: L Ivanova; Sami J Barmada; T Kummer; David A Harris
Mutant prion proteins are partially retained in the endoplasmic reticulum.
The Journal of biological chemistry 2001;276(45):42409-21.
2000: Nathaniel J Szewczyk; J J Hartman; Sami J Barmada; Lewis A Jacobson
Genetic defects in acetylcholine signalling promote protein degradation in muscle cells of Caenorhabditis elegans.
Journal of cell science 2000;113 ( Pt 11)():2003-10.
1997: L A Zdinak; I B Greenberg; Nathaniel J Szewczyk; Sami J Barmada; M Cardamone-Rayner; J J Hartman; Lewis A Jacobson
Transgene-coded chimeric proteins as reporters of intracellular proteolysis: starvation-induced catabolism of a lacZ fusion protein in muscle cells of Caenorhabditis elegans.
Journal of cellular biochemistry 1997;67(1):143-53.