FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Sarah Lincoln

Research Profile

Disorders

Physiology

Chemicals & Drugs

Concepts & Ideas

Procedures

Genes & Molecular Sequences

Single Nucleotide Polymorphism

Anatomy

Brain

Co-author Network

Publications

TOP 3
Christopher J Klein; John Kwok; Sarah J Lincoln; Georges Mer; Tom Bird; Peter J Dyck; Nilüfer Ertekin-Taner; Robert Hjorth; Yanhong Wu; Garth A Nicholson
DNMT1 mutation hot spot causes varied phenotypes of HSAN1 with dementia and hearing loss.
Andreas Puschmann; Stig Rehncrona; Owen A Ross; Anna-Lena Törnqvist; Carles vilarino-guell; Håkan Widner; Zbigniew K Wszolek; Stephanie A Cobb; Elisabet Englund; Matthew J Farrer; Jennifer Kachergus; Sarah J Lincoln; Christer Nilsson
First neuropathological description of a patient with Parkinson's disease and LRRK2 p.N1437H mutation.
Kelly M Hinkle; Christopher J Janus; Caroline B Kent; Wen-Lang Lin; Sarah J Lincoln; Joel E Beevers; Bahareh Behrouz; Erin E Bowles; Justus C Dächsel; Dennis W Dickson; Brittany Dugger; Matthew J Farrer; Kenya Nishioka; Iryna Prots; Beate Winner; Mei Yue; Heather L Melrose
LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Sarah Lincoln (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Christopher J Klein; John Kwok; Sarah J Lincoln; Georges Mer; Tom Bird; Peter J Dyck; Nilüfer Ertekin-Taner; Robert Hjorth; Yanhong Wu; Garth A Nicholson
DNMT1 mutation hot spot causes varied phenotypes of HSAN1 with dementia and hearing loss.
Neurology 2013;80(9):824-8.
2012: Andreas Puschmann; Stig Rehncrona; Owen A Ross; Anna-Lena Törnqvist; Carles vilarino-guell; Håkan Widner; Zbigniew K Wszolek; Stephanie A Cobb; Elisabet Englund; Matthew J Farrer; Jennifer Kachergus; Sarah J Lincoln; Christer Nilsson
First neuropathological description of a patient with Parkinson's disease and LRRK2 p.N1437H mutation.
Parkinsonism & related disorders 2012;18(4):332-8.
2012: Kelly M Hinkle; Christopher J Janus; Caroline B Kent; Wen-Lang Lin; Sarah J Lincoln; Joel E Beevers; Bahareh Behrouz; Erin E Bowles; Justus C Dächsel; Dennis W Dickson; Brittany Dugger; Matthew J Farrer; Kenya Nishioka; Iryna Prots; Beate Winner; Mei Yue; Heather L Melrose
LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors.
Molecular neurodegeneration 2012;7():25.
2011: Sun Ju Chung; Sebastian M Armasu; Joanna M Biernacka; Timothy G Lesnick; David N Rider; Sarah J Lincoln; Alexandra I Ortolaza; Matthew J Farrer; Julie M Cunningham; Walter A Rocca; Demetrius M Maraganore
Common variants in PARK loci and related genes and Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2011;26(2):280-8.
2010: Heather L Melrose; Justus C Dächsel; B Behrouz; Sarah J Lincoln; M Yue; Kelly M Hinkle; C B Kent; E Korvatska; Julie P Taylor; L Witten; Y-Q Liang; J E Beevers; Mona Boules; B N Dugger; V A Serna; A Gaukhman; X Yu; M Castanedes-Casey; A T Braithwaite; S Ogholikhan; N Yu; D Bass; Glenn M Tyndall; Gerard D Schellenberg; dennis dickson; C Janus; Matthew J Farrer
Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice.
Neurobiology of disease 2010;40(3):503-17.
2010: Jan Aasly; Carles vilarino-guell; Justus C Dachsel; Philip J Webber; Andrew B West; Kristoffer Haugarvoll; Krisztina K Johansen; Mathias Toft; John G Nutt; Haydeh Payami; Jennifer Kachergus; Sarah J Lincoln; Amela Felic; Christian Wider; Alexandra I Soto-Ortolaza; Stephanie A Cobb; Linda R White; Owen A Ross; Matthew J Farrer
Novel pathogenic LRRK2 p.Asn1437His substitution in familial Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2010;25(13):2156-63.
2010: Kenya Nishioka; Christian Wider; Carles vilarino-guell; Alexandra I Soto-Ortolaza; Sarah J Lincoln; Jennifer Kachergus; Barbara Jasinska-Myga; Owen A Ross; Alex Rajput; Christopher A Robinson; Tanis J Ferman; Zbigniew K Wszolek; dennis dickson; Matthew J Farrer
Association of alpha-, beta-, and gamma-Synuclein with diffuse lewy body disease.
Archives of neurology 2010;67(8):970-5.
2010: Justus C Dachsel; Kenya Nishioka; Carles vilarino-guell; Sarah J Lincoln; Alexandra I Soto-Ortolaza; Jennifer Kachergus; Kelly M Hinkle; Michael G Heckman; Barbara Jasinska-Myga; Julie P Taylor; dennis dickson; Rachel A Gibson; Faycal Hentati; Owen A Ross; Matthew J Farrer
Heterodimerization of Lrrk1-Lrrk2: Implications for LRRK2-associated Parkinson disease.
Mechanisms of ageing and development 2010;131(3):210-4.
2009: Ali H Rajput; Carles vilarino-guell; Michelle Rajput; Owen A Ross; Alexandra I Soto-Ortolaza; Sarah J Lincoln; Stephanie A Cobb; Michael G Heckman; Matthew J Farrer; Alex Rajput
Alpha-synuclein polymorphisms are associated with Parkinson's disease in a Saskatchewan population.
Movement disorders : official journal of the Movement Disorder Society 2009;24(16):2411-4.
2009: Andreas Puschmann; Owen A Ross; Carles vilarino-guell; Sarah J Lincoln; Jennifer Kachergus; Stephanie A Cobb; Suzanne G Lindquist; Jørgen E Nielsen; Zbigniew K Wszolek; Matthew J Farrer; Håkan Widner; Danielle van Westen; Douglas Hägerström; Katerina Markopoulou; Bruce A Chase; Karin Nilsson; Jan Reimer; Christer Nilsson
A Swedish family with de novo alpha-synuclein A53T mutation: evidence for early cortical dysfunction.
Parkinsonism & related disorders 2009;15(9):627-32.
2009: Christian Wider; Sarah J Lincoln; Justus C Dachsel; Gregory Kapatos; Michael G Heckman; Nancy N Diehl; Spiridon Papapetropoulos; Deborah C Mash; Alex Rajput; Ali H Rajput; dennis dickson; Zbigniew K Wszolek; Matthew J Farrer
GCH1 expression in human cerebellum from healthy individuals is not gender dependent.
Neuroscience letters 2009;462(1):73-5.
2009: Beate Ritz; Angelika D Manthripragada; Sadie Costello; Sarah J Lincoln; Matthew J Farrer; Myles G Cockburn; Jeff Bronstein
Dopamine transporter genetic variants and pesticides in Parkinson's disease.
Environmental health perspectives 2009;117(6):964-9.
2009: Christian Wider; Sarah J Lincoln; Michael G Heckman; Nancy N Diehl; Jeremy T Stone; Kristoffer Haugarvoll; Jan Aasly; J Mark Gibson; Timothy Lynch; Alex Rajput; Michele L Rajput; Ryan Uitti; Zbigniew K Wszolek; Matthew J Farrer; Owen A Ross
Phactr2 and Parkinson's disease.
Neuroscience letters 2009;453(1):9-11.
2009: Carles vilarino-guell; Alexandra I Soto; Sarah J Lincoln; Samia Ben Yahmed; Mounir Kefi; Michael G Heckman; Mary Hulihan; Hua Chai; Nancy N Diehl; Rim Amouri; Alex Rajput; Deborah C Mash; dennis dickson; Lefkos T Middleton; Rachel A Gibson; Faycal Hentati; Matthew J Farrer
ATP13A2 variability in Parkinson disease.
Human mutation 2009;30(3):406-10.
2009: Christian Wider; Justus C Dachsel; Alexandra I Soto; Michael G Heckman; Nancy N Diehl; Mei Yue; Sarah J Lincoln; Jan Aasly; Kristoffer Haugarvoll; John Q Trojanowski; Spiridon Papapetropoulos; Deborah C Mash; Alex Rajput; Ali H Rajput; J Mark Gibson; Timothy Lynch; dennis dickson; Ryan Uitti; Zbigniew K Wszolek; Matthew J Farrer; Owen A Ross
FGF20 and Parkinson's disease: no evidence of association or pathogenicity via alpha-synuclein expression.
Movement disorders : official journal of the Movement Disorder Society 2009;24(3):455-9.
2009: Ming-Jen Lee; Ignacio F Mata; Chin-Hsien Lin; Kai-Yuan Tzen; Sarah J Lincoln; Rebecca Bounds; Paul J Lockhart; Mary Hulihan; Matthew J Farrer; Ruey-Meei Wu
Genotype-phenotype correlates in Taiwanese patients with early-onset recessive Parkinsonism.
Movement disorders : official journal of the Movement Disorder Society 2009;24(1):104-8.
2008: Rosa Rademakers; Jason Eriksen; Matt Baker; Todd Robinson; Zeshan Ahmed; Sarah J Lincoln; Nicole Finch; Nicola J Rutherford; Richard J Crook; Keith A Josephs; Bradley Boeve; David S. Knopman; Ronald C. Petersen; Joseph E Parisi; Richard Caselli; Zbigniew K Wszolek; Ryan Uitti; Howard Feldman; Michael Hutton; Ian R Mackenzie; Neill R Graff-Radford; dennis dickson
Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia.
Human molecular genetics 2008;17(23):3631-42.
2008: L Brighina; Roberta Frigerio; N K Schneider; Timothy G Lesnick; Mariza de Andrade; Julie M Cunningham; Matthew J Farrer; Sarah J Lincoln; Harvey Checkoway; Walter A Rocca; Demetrius M Maraganore
Alpha-synuclein, pesticides, and Parkinson disease: a case-control study.
Neurology 2008;70(16 Pt 2):1461-9.
2008: Jada Lewis; Heather L Melrose; David Bumcrot; Andrew Hope; Cynthia Zehr; Sarah J Lincoln; Adam Braithwaite; Zhen He; Sina Ogholikhan; Kelly M Hinkle; Caroline Kent; Ivanka Toudjarska; Klaus Charisse; Ravi Braich; Rajendra K Pandey; Michael G Heckman; Demetrius M Maraganore; Julia Crook; Matthew J Farrer
In vivo silencing of alpha-synuclein using naked siRNA.
Molecular neurodegeneration 2008;3():19.
2007: Susen Winkler; Johann Hagenah; Sarah J Lincoln; Michael G Heckman; K Haugarvoll; Katja Lohmann-Hedrich; Vladimir Kostic; Matthew J Farrer; Christine Klein
alpha-Synuclein and Parkinson disease susceptibility.
Neurology 2007;69(18):1745-50.
2007: Sarah J Lincoln; Owen A Ross; Nicole M Milkovic; dennis dickson; Alex Rajput; Christopher A Robinson; Spiridon Papapetropoulos; Deborah C Mash; Matthew J Farrer
Quantitative PCR-based screening of alpha-synuclein multiplication in multiple system atrophy.
Parkinsonism & related disorders 2007;13(6):340-2.
2007: Heather L Melrose; C B Kent; Julie P Taylor; J C Dachsel; Kelly M Hinkle; Sarah J Lincoln; Su San Mok; Janetta G Culvenor; Colin L Masters; Glenn M Tyndall; D I Bass; Zeshan Ahmed; Cathy Andorfer; Owen A Ross; Zbigniew K Wszolek; A Delldonne; dennis dickson; Matthew J Farrer
A comparative analysis of leucine-rich repeat kinase 2 (Lrrk2) expression in mouse brain and Lewy body disease.
Neuroscience 2007;147(4):1047-58.
2007: Laura Brighina; Njideka Okubadejo; Nicole K Schneider; Timothy G Lesnick; Mariza de Andrade; Julie M Cunningham; Matthew J Farrer; Sarah J Lincoln; Walter A Rocca; Demetrius M Maraganore
Beta-synuclein gene variants and Parkinson's disease: a preliminary case-control study.
Neuroscience letters 2007;420(3):229-34.
2007: Owen A Ross; David Gosal; Jeremy T Stone; Sarah J Lincoln; Michael G Heckman; G Brent Irvine; Janet A Johnston; J Mark Gibson; Matthew J Farrer; Timothy Lynch
Familial genes in sporadic disease: common variants of alpha-synuclein gene associate with Parkinson's disease.
Mechanisms of ageing and development 2007;128(5-6):378-82.
2007: Stacey Melquist; David Craig; Matthew Huentelman; Richard Crook; John Pearson; Matt Baker; Victoria L Zismann; Jennifer Gass; Jennifer Adamson; Szabolcs Szelinger; Jason Corneveaux; Ashley Cannon; Keith D Coon; Sarah J Lincoln; Charles H Adler; Paul Tuite; Donald B Calne; Eileen H Bigio; Ryan Uitti; Zbigniew K Wszolek; Lawrence I Golbe; Richard Caselli; Neill R Graff-Radford; Irene Litvan; Matthew J Farrer; dennis dickson; Michael Hutton; Dietrich A Stephan
Identification of a novel risk locus for progressive supranuclear palsy by a pooled genomewide scan of 500,288 single-nucleotide polymorphisms.
American journal of human genetics 2007;80(4):769-78.
2007: Julie P Taylor; Mary Hulihan; Jennifer Kachergus; Heather L Melrose; Sarah J Lincoln; Kelly M Hinkle; Jeremy T Stone; Owen A Ross; Robert A Hauser; Jan Aasly; Thomas Gasser; Haydeh Payami; Zbigniew K Wszolek; Matthew J Farrer
Leucine-rich repeat kinase 1: a paralog of LRRK2 and a candidate gene for Parkinson's disease.
Neurogenetics 2007;8(2):95-102.
2007: Justus C Dächsel; Sarah J Lincoln; John Gonzalez; Owen A Ross; dennis dickson; Matthew J Farrer
The ups and downs of alpha-synuclein mRNA expression.
Movement disorders : official journal of the Movement Disorder Society 2007;22(2):293-5.
2006: Justus C Dächsel; Ignacio Mata; Owen A Ross; Julie P Taylor; Sarah J Lincoln; Kelly M Hinkle; Cecilia Huerta; Renee Ribacoba; Marta Blazquez; Victoria Alvarez; Matthew J Farrer
Digenic parkinsonism: investigation of the synergistic effects of PRKN and LRRK2.
Neuroscience letters 2006;410(2):80-4.
2006: Alex Rajput; dennis dickson; Christopher A Robinson; Owen A Ross; Justus C Dächsel; Sarah J Lincoln; S A Cobb; Michelle Rajput; Matthew J Farrer
Parkinsonism, Lrrk2 G2019S, and tau neuropathology.
Neurology 2006;67(8):1506-8.
2006: Demetrius M Maraganore; Mariza de Andrade; Alexis Elbaz; Matthew J Farrer; John Ioannidis; Rejko Krüger; Walter A Rocca; Nicole K Schneider; Timothy G Lesnick; Sarah J Lincoln; Mary Hulihan; Jan Aasly; Tetsuo Ashizawa; Marie-Christine Chartier-Harlin; Harvey Checkoway; Carlo Ferrarese; Georgios M Hadjigeorgiou; Nobutaka Hattori; Hideshi Kawakami; jean-charles lambert; Timothy Lynch; George D Mellick; Spiridon Papapetropoulos; Abbas Parsian; Aldo Quattrone; Olaf Riess; Eng-King Tan; Christine Van Broeckhoven
Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease.
JAMA : the journal of the American Medical Association 2006;296(6):661-70.
2006: Heather L Melrose; Sarah J Lincoln; Glenn M Tyndall; Matthew J Farrer
Parkinson's disease: a rethink of rodent models.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2006;173(2):196-204.
2006: Matthew J Farrer; Kristoffer Haugarvoll; Owen A Ross; Jeremy T Stone; Nicole M Milkovic; Stephanie A Cobb; Andrew J Whittle; Sarah J Lincoln; Mary Hulihan; Michael G Heckman; Linda R White; Jan Aasly; J Mark Gibson; David Gosal; Timothy Lynch; Zbigniew K Wszolek; Ryan Uitti; Mathias Toft
Genomewide association, Parkinson disease, and PARK10.
American journal of human genetics 2006;78(6):1084-8; author reply 1092-4.
2006: Owen A Ross; Andrew J Whittle; Stephanie A Cobb; Mary Hulihan; Sarah J Lincoln; Mathias Toft; Matthew J Farrer; dennis dickson
Lrrk2 R1441 substitution and progressive supranuclear palsy.
Neuropathology and applied neurobiology 2006;32(1):23-5.
2006: Heather L Melrose; Sarah J Lincoln; Glenn M Tyndall; dennis dickson; Matthew J Farrer
Anatomical localization of leucine-rich repeat kinase 2 in mouse brain.
Neuroscience 2006;139(3):791-4.
2005: Ignacio Mata; Jennifer Kachergus; Julie P Taylor; Sarah J Lincoln; Jan Aasly; Timothy Lynch; Mary Hulihan; Stephanie A Cobb; Ruey-Meei Wu; Chin-Song Lu; Carlos Lahoz; Zbigniew K Wszolek; Matthew J Farrer
Lrrk2 pathogenic substitutions in Parkinson's disease.
Neurogenetics 2005;6(4):171-7.
2005: Matthew J Farrer; J Stone; Ignacio Mata; Sarah J Lincoln; Jennifer Kachergus; Mary Hulihan; Kari J Strain; Demetrius M Maraganore
LRRK2 mutations in Parkinson disease.
Neurology 2005;65(5):738-40.
2005: David Gosal; Owen A Ross; Joseph Wiley; G Brent Irvine; Janet A Johnston; Mathias Toft; Ignacio Mata; Jennifer Kachergus; Mary Hulihan; Julie P Taylor; Sarah J Lincoln; Matthew J Farrer; Timothy Lynch; J Mark Gibson
Clinical traits of LRRK2-associated Parkinson's disease in Ireland: a link between familial and idiopathic PD.
Parkinsonism & related disorders 2005;11(6):349-52.
2005: Maurizio Facheris; Kari J Strain; Timothy G Lesnick; Mariza de Andrade; James H Bower; J Eric Ahlskog; Julie M Cunningham; Sarah J Lincoln; Matthew J Farrer; Walter A Rocca; Demetrius M Maraganore
UCHL1 is associated with Parkinson's disease: a case-unaffected sibling and case-unrelated control study.
Neuroscience letters 2005;381(1-2):131-4.
2005: Ignacio Mata; Victoria Alvarez; Eliecer Coto; Marta Blazquez; Luis M Guisasola; Carlos Salvador; Jennifer Kachergus; Sarah J Lincoln; Matthew J Farrer
Homozygous partial genomic triplication of the parkin gene in early-onset parkinsonism.
Neuroscience letters 2005;380(3):257-9.
2005: Jennifer Kachergus; Ignacio Mata; Mary Hulihan; Julie P Taylor; Sarah J Lincoln; Jan Aasly; J Mark Gibson; Owen A Ross; Timothy Lynch; Joseph Wiley; Haydeh Payami; John G Nutt; Demetrius M Maraganore; Krzysztof Czyzewski; Maria Styczynska; Zbigniew K Wszolek; Matthew J Farrer; Mathias Toft
Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: evidence of a common founder across European populations.
American journal of human genetics 2005;76(4):672-80.
2005: Catherine E Mamah; Timothy G Lesnick; Sarah J Lincoln; Kari J Strain; Mariza de Andrade; James H Bower; J Eric Ahlskog; Walter A Rocca; Matthew J Farrer; Demetrius M Maraganore
Interaction of alpha-synuclein and tau genotypes in Parkinson's disease.
Annals of neurology 2005;57(3):439-43.
2005: Ruey-Meei Wu; Rebecca Bounds; Sarah J Lincoln; Mary Hulihan; Chin-Hsien Lin; Wuh-Liang Hwu; Judy Chen; Katrina Gwinn-Hardy; Matthew J Farrer
Parkin mutations and early-onset parkinsonism in a Taiwanese cohort.
Archives of neurology 2005;62(1):82-7.
2004: Alexander Zimprich; Saskia Biskup; Petra Leitner; Peter Lichtner; Matthew J Farrer; Sarah J Lincoln; Jennifer Kachergus; Mary Hulihan; Ryan Uitti; Donald B Calne; A Jon Stoessl; Ronald F Pfeiffer; Nadja Patenge; Iria Carballo Carbajal; Peter Vieregge; Friedrich Asmus; Bertram Müller-Myhsok; dennis dickson; Thomas Meitinger; Tim M Strom; Zbigniew K Wszolek; Thomas Gasser
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology.
Neuron 2004;44(4):601-7.
2004: Philippe Pals; Sarah J Lincoln; Jonathan Manning; Michael G Heckman; Lisa Skipper; Mary Hulihan; Marleen Van den Broeck; Tim De Pooter; Patrick Cras; Julia Crook; Christine Van Broeckhoven; Matthew J Farrer
alpha-Synuclein promoter confers susceptibility to Parkinson's disease.
Annals of neurology 2004;56(4):591-5.
2004: Lisa Skipper; Kristen Wilkes; Mathias Toft; Matthew Baker; Sarah J Lincoln; Mary Hulihan; Owen A Ross; Michael Hutton; Jan Aasly; Matthew J Farrer
Linkage disequilibrium and association of MAPT H1 in Parkinson disease.
American journal of human genetics 2004;75(4):669-77.
2004: Marie-Christine Chartier-Harlin; Jennifer Kachergus; Christophe Roumier; Vincent Mouroux; Xavier Douay; Sarah J Lincoln; Clotilde Levecque; Lydie Larvor; Joris Andrieux; Mary Hulihan; Nawal Waucquier; Luc Defebvre; Philippe Amouyel; Matthew J Farrer; Alain Destée
Alpha-synuclein locus duplication as a cause of familial Parkinson's disease.
Lancet 2004;364(9440):1167-9.
2004: Paul J Lockhart; Rebecca Bounds; Mary Hulihan; Jennifer Kachergus; Sarah J Lincoln; Chin-Hsien Lin; Ruey-Meei Wu; Matthew J Farrer
Lack of mutations in DJ-1 in a cohort of Taiwanese ethnic Chinese with early-onset parkinsonism.
Movement disorders : official journal of the Movement Disorder Society 2004;19(9):1065-9.
2004: Andrew D Hope; Ronny Myhre; Jennifer Kachergus; Sarah J Lincoln; Gina Bisceglio; Mary Hulihan; Matthew J Farrer
Alpha-synuclein missense and multiplication mutations in autosomal dominant Parkinson's disease.
Neuroscience letters 2004;367(1):97-100.
2004: Casey O'Farrell; Paul J Lockhart; Sarah J Lincoln; Michael De Lucia; Andrew Singleton; dennis dickson; Mark Cookson
Biochemical characterization of torsinB.
Brain research. Molecular brain research 2004;127(1-2):1-9.
2004: Demetrius M Maraganore; Kristen Wilkes; Timothy G Lesnick; Kari J Strain; Mariza de Andrade; Walter A Rocca; James H Bower; J Eric Ahlskog; Sarah J Lincoln; Matthew J Farrer
A limited role for DJ1 in Parkinson disease susceptibility.
Neurology 2004;63(3):550-3.
2004: Joseph Wiley; Timothy Lynch; Sarah J Lincoln; Lisa Skipper; Mary Hulihan; David Gosal; Gina Bisceglio; Jennifer Kachergus; John Hardy; Matthew J Farrer
Parkinson's disease in Ireland: clinical presentation and genetic heterogeneity in patients with parkin mutations.
Movement disorders : official journal of the Movement Disorder Society 2004;19(6):677-81.
2004: Paul J Lockhart; Sarah J Lincoln; Mary Hulihan; Jennifer Kachergus; Kristen Wilkes; Gina Bisceglio; Deborah C Mash; Matthew J Farrer
DJ-1 mutations are a rare cause of recessively inherited early onset parkinsonism mediated by loss of protein function.
Journal of medical genetics 2004;41(3):e22.
2004: Paul J Lockhart; Mary Hulihan; Sarah J Lincoln; Jennifer Hussey; Lisa Skipper; Gina Bisceglio; Kristen Wilkes; Matthew J Farrer
Identification of the human ubiquitin specific protease 31 (USP31) gene: structure, sequence and expression analysis.
DNA sequence : the journal of DNA sequencing and mapping 2004;15(1):9-14.
2004: Matthew J Farrer; Jennifer Kachergus; Lysia Forno; Sarah J Lincoln; Dengshun Wang; Mary Hulihan; Demetrius M Maraganore; Katrina Gwinn-Hardy; Zbigniew K Wszolek; dennis dickson; J William Langston
Comparison of kindreds with parkinsonism and alpha-synuclein genomic multiplications.
Annals of neurology 2004;55(2):174-9.
2004: Paul J Lockhart; Jennifer Kachergus; Sarah J Lincoln; Mary Hulihan; Gina Bisceglio; Natalie Thomas; dennis dickson; Matthew J Farrer
Multiplication of the alpha-synuclein gene is not a common disease mechanism in Lewy body disease.
Journal of molecular neuroscience : MN 2004;24(3):337-42.
2003: Henry Houlden; Sarah J Lincoln; Matthew J Farrer; P G Cleland; John Hardy; Richard W Orrell
Compound heterozygous PANK2 mutations confirm HARP and Hallervorden-Spatz syndromes are allelic.
Neurology 2003;61(10):1423-6.
2003: Sarah J Lincoln; Demetrius M Maraganore; Timothy G Lesnick; Rebecca Bounds; Mariza de Andrade; James H Bower; John Hardy; Matthew J Farrer
Parkin variants in North American Parkinson's disease: cases and controls.
Movement disorders : official journal of the Movement Disorder Society 2003;18(11):1306-11.
2003: Andrew B Singleton; Matthew J Farrer; Janel Johnson; Andrew Singleton; Stephen Hague; Jennifer Kachergus; Mary Hulihan; Terhi Peuralinna; A Dutra; Robert L Nussbaum; Sarah J Lincoln; Anthony Crawley; Melissa Hanson; Demetrius M Maraganore; Charles H Adler; Mark Cookson; MD Muenter; Melisa J Baptista; D Miller; J Blancato; John Hardy; Katrina Gwinn-Hardy
alpha-Synuclein locus triplication causes Parkinson's disease.
Science (New York, N.Y.) 2003;302(5646):841.
2003: Sarah J Lincoln; Joseph Wiley; Timothy Lynch; J William Langston; R Chen; Anthony E Lang; Ekaterina Rogaeva; Daniel S Sa; Renato P Munhoz; J Harris; Karen Marder; Christine Klein; Gina Bisceglio; Jennifer Hussey; A West; Mary Hulihan; John Hardy; Matthew J Farrer
Parkin-proven disease: common founders but divergent phenotypes.
Neurology 2003;60(10):1605-10.
2003: Nina Rawal; Magali Periquet; Ebba Lohmann; Christoph B Lücking; Hélio A G Teive; G Ambrosio; Salmo Raskin; Sarah J Lincoln; Nobutaka Hattori; Joao Guimaraes; Martin Horstink; W Dos Santos Bele; E Brousolle; Alain Destée; Yoshikuni Mizuno; Matthew J Farrer; Jean-François Deleuze; Giuseppe De Michele; Yves Agid; Alexandra Dürr; Alexis Brice
New parkin mutations and atypical phenotypes in families with autosomal recessive parkinsonism.
Neurology 2003;60(8):1378-81.
2002: Andrew West; Magali Periquet; Sarah J Lincoln; Christoph B Lücking; David Nicholl; Vincenzo Bonifati; Nina Rawal; Thomas Gasser; Ebba Lohmann; Jean-François Deleuze; Demetrius M Maraganore; Allan Levey; Nicholas W Wood; Alexandra Dürr; John Hardy; Alexis Brice; Matthew J Farrer
Complex relationship between Parkin mutations and Parkinson disease.
American journal of medical genetics 2002;114(5):584-91.
2002: Ruey-Meei Wu; Din-E Shan; Chen-Ming Sun; Ren-Shyan Liu; Wuh-Liang Hwu; Chun-Hwei Tai; Jennifer Hussey; Andrew West; Katrina Gwinn-Hardy; John Hardy; Judy Chen; Matthew J Farrer; Sarah J Lincoln
Clinical, 18F-dopa PET, and genetic analysis of an ethnic Chinese kindred with early-onset parkinsonism and parkin gene mutations.
Movement disorders : official journal of the Movement Disorder Society 2002;17(4):670-5.
2002: Brad A Racette; M Rundle; Jen C Wang; Alison Goate; N L Saccone; Matthew J Farrer; Sarah J Lincoln; J Hussey; Scott Smemo; J Lin; Brian K Suarez; Abbas Parsian; Joel S Perlmutter
A multi-incident, Old-Order Amish family with PD.
Neurology 2002;58(4):568-74.
2002: Paul J Lockhart; Benjamin Holtom; Sarah J Lincoln; Jennifer Hussey; Alexander Zimprich; Thomas Gasser; Zbigniew K Wszolek; John Hardy; Matthew J Farrer
The human sideroflexin 5 (SFXN5) gene: sequence, expression analysis and exclusion as a candidate for PARK3.
Gene 2002;285(1-2):229-37.
2002: David Nicholl; Jenny R Vaughan; Naheed L Khan; Shu-Leong Ho; D E W Aldous; Sarah J Lincoln; Matthew J Farrer; J D Gayton; Mary B Davis; Paola Piccini; Susan E Daniel; Graham Lennox; David J Brooks; AC Williams; Nicholas W Wood
Two large British kindreds with familial Parkinson's disease: a clinico-pathological and genetic study.
Brain : a journal of neurology 2002;125(Pt 1):44-57.
2001: Andrew B West; Alexander Zimprich; Paul J Lockhart; Matthew J Farrer; Andrew Singleton; B Holtom; Sarah J Lincoln; A Hofer; L Hill; Bertram Müller-Myhsok; Zbigniew K Wszolek; John Hardy; Thomas Gasser
Refinement of the PARK3 locus on chromosome 2p13 and the analysis of 14 candidate genes.
European journal of human genetics : EJHG 2001;9(9):659-66.
2001: Matthew J Farrer; Piu Chan; R Chen; Louis Tan ; Sarah J Lincoln; D Hernandez; Lysia Forno; Katrina Gwinn-Hardy; Leonard Petrucelli; Jennifer Hussey; Andrew Singleton; Caroline M Tanner; John Hardy; J William Langston
Lewy bodies and parkinsonism in families with parkin mutations.
Annals of neurology 2001;50(3):293-300.
2001: Yasuji Matsuoka; Miquel Vila; Sarah J Lincoln; Alison L McCormack; M Picciano; John LaFrancois; X Yu; dennis dickson; William J Langston; E McGowan; Matthew J Farrer; John Hardy; karen duff; Serge Przedborski; Donato A Di Monte
Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter.
Neurobiology of disease 2001;8(3):535-9.
2001: dennis dickson; Matthew J Farrer; Sarah J Lincoln; R P Mason; T R Zimmerman; Lawrence I Golbe; John Hardy
Pathology of PD in monozygotic twins with a 20-year discordance interval.
Neurology 2001;56(7):981-2.
2000: Matthew J Farrer; T Destée; E Becquet; Fabienne Wavrant-De Vrièze; Vincent Mouroux; Florence Richard; Luc Defebvre; Sarah J Lincoln; John Hardy; Philippe Amouyel; Marie-Christine Chartier-Harlin
Linkage exclusion in French families with probable Parkinson' s disease.
Movement disorders : official journal of the Movement Disorder Society 2000;15(6):1075-83.
2000: Katrina Gwinn-Hardy; Richard Crook; Sarah J Lincoln; Charles H Adler; John Caviness; John Hardy; Matthew J Farrer
A kindred with Parkinson's disease not showing genetic linkage to established loci.
Neurology 2000;54(2):504-7.
1999: Demetrius M Maraganore; Matthew J Farrer; John Hardy; Sarah J Lincoln; Shannon K McDonnell; Walter A Rocca
Case-control study of the ubiquitin carboxy-terminal hydrolase L1 gene in Parkinson's disease.
Neurology 1999;53(8):1858-60.
1999: Guy Prihar; A Verkkoniem; Jordi Perez-Tur; Richard Crook; Sarah J Lincoln; Henry Houlden; Mirja Somer; Anders Paetau; Hannu Kalimo; Andrew Grover; Liisa Myllykangas; Michael Hutton; John Hardy; Matti Haltia
Alzheimer disease PS-1 exon 9 deletion defined.
Nature medicine 1999;5(10):1090.
1999: Harald Steiner; karen duff; Anja Capell; H Romig; MG Grim; Sarah J Lincoln; John Hardy; X Yu; M Picciano; K Fechteler; Martin Citron; R Kopan; B Pesold; S Keck; Miriam Baader; Taisuke Tomita; Takeshi Iwatsubo; Ralf Baumeister; Christian Haass
A loss of function mutation of presenilin-2 interferes with amyloid beta-peptide production and notch signaling.
The Journal of biological chemistry 1999;274(40):28669-73.
1999: Biswadjiet S Harhangi; Matthew J Farrer; Sarah J Lincoln; Vincenzo Bonifati; Giuseppe Meco; Giuseppe De Michele; Alexis Brice; Alexandra Dürr; M Martinez; Thomas Gasser; Benjamin Bereznai; Jenny R Vaughan; Nicholas W Wood; John Hardy; Ben A Oostra; Monique Breteler
The Ile93Met mutation in the ubiquitin carboxy-terminal-hydrolase-L1 gene is not observed in European cases with familial Parkinson's disease.
Neuroscience letters 1999;270(1):1-4.
1999: Sarah J Lincoln; Richard Crook; Marie-Christine Chartier-Harlin; Katrina Gwinn-Hardy; Matt Baker; Vincent Mouroux; Florence Richard; E Becquet; Philippe Amouyel; Alain Destée; John Hardy; Matthew J Farrer
No pathogenic mutations in the beta-synuclein gene in Parkinson's disease.
Neuroscience letters 1999;269(2):107-9.
1999: Sarah J Lincoln; J Vaughan; Nicholas W Wood; Matt Baker; J Adamson; Katrina Gwinn-Hardy; Timothy Lynch; John Hardy; Matthew J Farrer
Low frequency of pathogenic mutations in the ubiquitin carboxy-terminal hydrolase gene in familial Parkinson's disease.
Neuroreport 1999;10(2):427-9.
1999: Sarah J Lincoln; Katrina Gwinn-Hardy; John Goudreau; Marie-Christine Chartier-Harlin; Matt Baker; Vincent Mouroux; Florence Richard; Alain Destée; E Becquet; Philippe Amouyel; Timothy Lynch; John Hardy; Matthew J Farrer
No pathogenic mutations in the persyn gene in Parkinson's disease.
Neuroscience letters 1999;259(1):65-6.
1999: Matthew J Farrer; Katrina Gwinn-Hardy; MD Muenter; FW DeVrieze; Richard Crook; Jordi Perez-Tur; Sarah J Lincoln; Demetrius M Maraganore; Charles H Adler; S Newman; K MacElwee; P McCarthy; C Miller; C Waters; John Hardy
A chromosome 4p haplotype segregating with Parkinson's disease and postural tremor.
Human molecular genetics 1999;8(1):81-5.
1998: Michael Hutton; C L Lendon; P Rizzu; M Baker; S Froelich; H Houlden; S Pickering-Brown; S Chakraverty; A Isaacs; Andrew Grover; J Hackett; J Adamson; Sarah J Lincoln; dennis dickson; Peter Davies; Ronald C. Petersen; M Stevens; E de Graaff; E Wauters; J van Baren; M Hillebrand; M Joosse; J M Kwon; P Nowotny; L K Che; J Norton; John C Morris; L A Reed; John Q Trojanowski; Hans Basun; Lars Lannfelt; M Neystat; Stanley Fahn; F Dark; T Tannenberg; P R Dodd; N Hayward; J B Kwok; P R Schofield; A Andreadis; J Snowden; D Craufurd; David Neary; F Owen; B A Oostra; John Hardy; Alison Goate; J van Swieten; D M A Mann; T Lynch; Peter Heutink
Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17.
Nature 1998;393(6686):702-5.
1998: Richard Crook; Auli Verkkoniemi; Jordi Perez-Tur; N Mehta; Matt Baker; Henry Houlden; Matthew J Farrer; Michael Hutton; Sarah J Lincoln; John Hardy; Katrina Gwinn-Hardy; Mirja Somer; Anders Paetau; Hannu Kalimo; Raija Ylikoski; M Pöyhönen; S Kucera; Matti Haltia
A variant of Alzheimer's disease with spastic paraparesis and unusual plaques due to deletion of exon 9 of presenilin 1.
Nature medicine 1998;4(4):452-5.
1998: Jenny R Vaughan; Matthew J Farrer; Zbigniew K Wszolek; Thomas Gasser; Alexandra Durr; Yves Agid; Vincenzo Bonifati; G DeMichele; Giampiero Volpe; Sarah J Lincoln; Monique Breteler; Giuseppe Meco; Alexis Brice; CD Marsden; John Hardy; Nicholas W Wood
Sequencing of the alpha-synuclein gene in a large series of cases of familial Parkinson's disease fails to reveal any further mutations. The European Consortium on Genetic Susceptibility in Parkinson's Disease (GSPD).
Human molecular genetics 1998;7(4):751-3.
1997: Matt Baker; John B J Kwok; S Kucera; Richard Crook; Matthew J Farrer; Henry Houlden; A Isaacs; Sarah J Lincoln; Luisa Onstead; John Hardy; L Wittenberg; P Dodd; S Webb; N Hayward; T Tannenberg; A Andreadis; Marianne Hallupp; P Schofield; F Dark; Michael Hutton
Localization of frontotemporal dementia with parkinsonism in an Australian kindred to chromosome 17q21-22.
Annals of neurology 1997;42(5):794-8.
1996: Guy Prihar; R A Fuldner; Jordi Perez-Tur; Sarah J Lincoln; karen duff; Richard Crook; John Hardy; C A Philips; C Venter; C Talbot; Robert Clark; Alison Goate; J Li; H Potter; EH Karran; G W Roberts; Michael Hutton; M D Adams
Structure and alternative splicing of the presenilin-2 gene.
Neuroreport 1996;7(10):1680-4.