FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Joel Linden

Research Profile

Chemicals & Drugs

Living Beings

Disorders

Procedures

Radioligand Assay

Anatomy

Co-author Network

Publications

TOP 3
David A Harris; Irving L Kron; Damien J LaPar; Joel Linden; John F Steidle; Mark Stoler; Yunge Zhao; Abbas Emaminia; Christine L Lau
Inhibiting CXCL12 blocks fibrocyte migration and differentiation and attenuates bronchiolitis obliterans in a murine heterotopic tracheal transplant model.
Cirle A Warren; Snjezana Zaja-Milatovic; Yuesheng Li; Joel Linden; Edward van Opstal; Gina M Calabrese; Robert A Figler; Rosemayre S Freire; Richard L Guerrant
Contribution of adenosine A(2B) receptors in Clostridium difficile intoxication and infection.
Li Li; Joel Linden; Peter I Lobo; Emily K Moser; Amandeep Bajwa; Yuan-Ji Day; Liping Huang; Katarzyna Jaworska; Gilbert R Kinsey; Sang Ju Lee; Diane L Rosin; Steven P Song; Hong Ye; Mark D Okusa
Dendritic cells tolerized with adenosine A₂AR agonist attenuate acute kidney injury.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Joel Linden (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: David A Harris; Irving L Kron; Damien J LaPar; Joel Linden; John F Steidle; Mark Stoler; Yunge Zhao; Abbas Emaminia; Christine L Lau
Inhibiting CXCL12 blocks fibrocyte migration and differentiation and attenuates bronchiolitis obliterans in a murine heterotopic tracheal transplant model.
The Journal of thoracic and cardiovascular surgery 2013;145(3):854-61.
2012: Cirle A Warren; Snjezana Zaja-Milatovic; Yuesheng Li; Joel Linden; Edward van Opstal; Gina M Calabrese; Robert A Figler; Rosemayre S Freire; Richard L Guerrant
Contribution of adenosine A(2B) receptors in Clostridium difficile intoxication and infection.
Infection and immunity 2012;80(12):4463-73.
2012: Li Li; Joel Linden; Peter I Lobo; Emily K Moser; Amandeep Bajwa; Yuan-Ji Day; Liping Huang; Katarzyna Jaworska; Gilbert R Kinsey; Sang Ju Lee; Diane L Rosin; Steven P Song; Hong Ye; Mark D Okusa
Dendritic cells tolerized with adenosine A₂AR agonist attenuate acute kidney injury.
The Journal of clinical investigation 2012;122(11):3931-42.
2012: Preeti Chhabra; Mark Douglas Okusa; Joel Linden; Peter Lobo; Kenneth Lewis Brayman
The immunosuppressive role of adenosine A2A receptors in ischemia reperfusion injury and islet transplantation.
Current diabetes reviews 2012;8(6):419-33.
2012: Yuesheng Li; Joel Linden; Jayson Rieger; Ralph W Stevenson; Tara C Bracken; Robert A Figler; Richard L Guerrant; Glynis Kolling; Cirle Alcantara Warren
Adenosine A2A receptor activation reduces recurrence and mortality from Clostridium difficile infection in mice following vancomycin treatment.
BMC infectious diseases 2012;12():342.
2012: Cirle Alcantara Warren; Gina M Calabrese; Peter B Ernst; Robert A Figler; Yuesheng Li; Joel Linden; Sean W Pawlowski; Jayson Rieger; Richard L Guerrant
Effects of adenosine A₂A receptor activation and alanyl-glutamine in Clostridium difficile toxin-induced ileitis in rabbits and cecitis in mice.
BMC infectious diseases 2012;12():13.
2011: Abbas Emaminia; David A Harris; Irving L Kron; Damien J Lapar; Victor E Laubach; Joel Linden; John F Steidle; Yunge Zhao; Christine L Lau
Adenosine A₂A agonist improves lung function during ex vivo lung perfusion.
The Annals of thoracic surgery 2011;92(5):1840-6.
2011: Jeffrey M Wilson; Mohammed S Alam; Steven G Black; Courtney C Kurtz; Joel Linden; William G Ross; Peter B Ernst
The A2B adenosine receptor promotes Th17 differentiation via stimulation of dendritic cell IL-6.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(12):6746-52.
2010: Kori L Wallace; Joel Linden
Adenosine A2A receptors induced on iNKT and NK cells reduce pulmonary inflammation and injury in mice with sickle cell disease.
Blood 2010;116(23):5010-20.
2010: Yunge Zhao; Damien J LaPar; John Steidle; Abbas Emaminia; Irving L Kron; Gorav Ailawadi; Joel Linden; Christine L Lau
Adenosine signaling via the adenosine 2B receptor is involved in bronchiolitis obliterans development.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2010;29(12):1405-14.
2010: Min Yang; Mahendra D Chordia; Fengping Li; Tao Huang; Joel Linden; Timothy L MacDonald
Neutrophil- and myeloperoxidase-mediated metabolism of reduced nimesulide: evidence for bioactivation.
Chemical research in toxicology 2010;23(11):1691-700.
2010: Leo M Gazoni; Dustin M Walters; Eric B Unger; Joel Linden; Irving L Kron; Victor E Laubach
Activation of A1, A2A, or A3 adenosine receptors attenuates lung ischemia-reperfusion injury.
The Journal of thoracic and cardiovascular surgery 2010;140(2):440-6.
2010: Shane M Devine; Alison Gregg; Heidi Figler; Kate McIntosh; Vijay Urmaliya; Joel Linden; Colin W Pouton; Paul J White; Steven E Bottle; Peter J Scammells
Synthesis and evaluation of new N6-substituted adenosine-5'-N-methylcarboxamides as A3 adenosine receptor agonists.
Bioorganic & medicinal chemistry 2010;18(9):3078-87.
2010: Ashish K Sharma; Victor E Laubach; Susan I Ramos; Yunge Zhao; George Stukenborg; Joel Linden; Irving L Kron; Zequan Yang
Adenosine A2A receptor activation on CD4+ T lymphocytes and neutrophils attenuates lung ischemia-reperfusion injury.
The Journal of thoracic and cardiovascular surgery 2010;139(2):474-82.
2010: Preeti Chhabra; Kunjie Wang; Qiang Zeng; Mladen Jecmenica; Linda Langman; Joel Linden; Robert J Ketchum; Kenneth L Brayman
Adenosine A(2A) agonist administration improves islet transplant outcome: Evidence for the role of innate immunity in islet graft rejection.
Cell transplantation 2010;19(5):597-612.
2009: Luigi Aurelio; Celine Valant; Heidi Figler; Bernard L Flynn; Joel Linden; Patrick M Sexton; Arthur Christopoulos; Peter J Scammells
3- and 6-Substituted 2-amino-4,5,6,7-tetrahydrothieno[2,3-c]pyridines as A1 adenosine receptor allosteric modulators and antagonists.
Bioorganic & medicinal chemistry 2009;17(20):7353-61.
2009: Christine L Lau; Yunge Zhao; Irving L Kron; Mark H Stoler; Victor E Laubach; Gorav Ailawadi; Joel Linden
The role of adenosine A2A receptor signaling in bronchiolitis obliterans.
The Annals of thoracic surgery 2009;88(4):1071-8.
2009: Rebecca E Cagnina; Susan I Ramos; Melissa A Marshall; Guoquan Wang; C Renea Frazier; Joel Linden
Adenosine A2B receptors are highly expressed on murine type II alveolar epithelial cells.
American journal of physiology. Lung cellular and molecular physiology 2009;297(3):L467-74.
2009: Rajan A G Patel; David K Glover; Alexis Broisat; Hasan K Kabul; Mirta Ruiz; N Craig Goodman; Christopher M Kramer; Denis J Meerdink; Joel Linden; George A Beller
Reduction in myocardial infarct size at 48 hours after brief intravenous infusion of ATL-146e, a highly selective adenosine A2A receptor agonist.
American journal of physiology. Heart and circulatory physiology 2009;297(2):H637-42.
2009: Kori L Wallace; Melissa A Marshall; Susan I Ramos; Joanne A Lannigan; Joshua J Field; Robert M Strieter; Joel Linden
NKT cells mediate pulmonary inflammation and dysfunction in murine sickle cell disease through production of IFN-gamma and CXCR3 chemokines.
Blood 2009;114(3):667-76.
2009: Christine L Lau; Yunge Zhao; Jiyoun Kim; Irving L Kron; Ashish Sharma; Zequan Yang; Victor E Laubach; Joel Linden; Gorav Ailawadi; David J Pinsky
Enhanced fibrinolysis protects against lung ischemia-reperfusion injury.
The Journal of thoracic and cardiovascular surgery 2009;137(5):1241-8.
2009: Landon W Locke; Mahendra D Chordia; Yi Zhang; Bijoy Kundu; Dylan Kennedy; Jessica Landseadel; Li Xiao; Karen D Fairchild; Stuart S Berr; Joel Linden; Dongfeng Pan
A novel neutrophil-specific PET imaging agent: cFLFLFK-PEG-64Cu.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(5):790-7.
2009: M S Alam; C C Kurtz; J M Wilson; B R Burnette; E B Wiznerowicz; William G Ross; Jayson M Rieger; Robert A Figler; Joel Linden; Sheila E Crowe; Peter B Ernst
A2A adenosine receptor (AR) activation inhibits pro-inflammatory cytokine production by human CD4+ helper T cells and regulates Helicobacter-induced gastritis and bacterial persistence.
Mucosal immunology 2009;2(3):232-42.
2009: Jeffrey M Wilson; William G Ross; Oma N Agbai; Renea Frazier; Robert A Figler; Jayson Rieger; Joel Linden; Peter B Ernst
The A2B adenosine receptor impairs the maturation and immunogenicity of dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(8):4616-23.
2009: Alaa S Awad; Michael Rouse; Liping Huang; Amy L Vergis; Jörg Reutershan; Helen P Cathro; Joel Linden; Mark D Okusa
Compartmentalization of neutrophils in the kidney and lung following acute ischemic kidney injury.
Kidney international 2009;75(7):689-98.
2009: Zequan Yang; Ashish K Sharma; Joel Linden; Irving L Kron; Victor E Laubach
CD4+ T lymphocytes mediate acute pulmonary ischemia-reperfusion injury.
The Journal of thoracic and cardiovascular surgery 2009;137(3):695-702; discussion 702.
2009: Mohammad S Alam; Courtney C Kurtz; Robert M Rowlett; Brian K Reuter; Elizabeth Wiznerowicz; Soumita Das; Joel Linden; Sheila E Crowe; Peter B Ernst
CD73 is expressed by human regulatory T helper cells and suppresses proinflammatory cytokine production and Helicobacter felis-induced gastritis in mice.
The Journal of infectious diseases 2009;199(4):494-504.
2009: Ashish K Sharma; Joel Linden; Irving L Kron; Victor E Laubach
Protection from pulmonary ischemia-reperfusion injury by adenosine A2A receptor activation.
Respiratory research 2009;10():58.
2008: Tyler H Rork; Kori L Wallace; Dylan P Kennedy; Melissa A Marshall; Amy R Lankford; Joel Linden
Adenosine A2A receptor activation reduces infarct size in the isolated, perfused mouse heart by inhibiting resident cardiac mast cell degranulation.
American journal of physiology. Heart and circulatory physiology 2008;295(5):H1825-33.
2008: Gemma N Ferguson; Celine Valant; James Horne; Heidi Figler; Bernard L Flynn; Joel Linden; David K Chalmers; Patrick M Sexton; Arthur Christopoulos; Peter J Scammells
2-aminothienopyridazines as novel adenosine A1 receptor allosteric modulators and antagonists.
Journal of medicinal chemistry 2008;51(19):6165-72.
2008: Peter I Ellman; T Brett Reece; Marianna G Law; Leo M Gazoni; Ramesh Singh; Victor E Laubach; Joel Linden; Curtis G Tribble; Irving L Kron
Adenosine A2A activation attenuates nontransplantation lung reperfusion injury.
The Journal of surgical research 2008;149(1):3-8.
2008: T Brett Reece; Curtis G Tribble; David O Okonkwo; Jonathon D Davis; Thomas S Maxey; Leo M Gazoni; Joel Linden; Irving L Kron; John A Kern
Early adenosine receptor activation ameliorates spinal cord reperfusion injury.
Journal of cardiovascular medicine (Hagerstown, Md.) 2008;9(4):363-7.
2008: Luigi Aurelio; Heidi Figler; Bernard L Flynn; Joel Linden; Peter J Scammells
5-Substituted 2-aminothiophenes as A1 adenosine receptor allosteric enhancers.
Bioorganic & medicinal chemistry 2008;16(3):1319-27.
2008: Christopher C Moore; Edward N Martin; Grace H Lee; Tom G Obrig; Joel Linden; W Michael Scheld
An A2A adenosine receptor agonist, ATL313, reduces inflammation and improves survival in murine sepsis models.
BMC infectious diseases 2008;8():141.
2008: Leo M Gazoni; Victor E Laubach; Daniel P Mulloy; Andrew Bellizzi; Eric B Unger; Joel Linden; Peter I Ellman; Turner C Lisle; Irving L Kron
Additive protection against lung ischemia-reperfusion injury by adenosine A2A receptor activation before procurement and during reperfusion.
The Journal of thoracic and cardiovascular surgery 2008;135(1):156-65.
2008: Alaa S Awad; Michael Rouse; Lixia Liu; Amy L Vergis; Diane L Rosin; Joel Linden; John R Sedor; Mark D Okusa
Activation of adenosine 2A receptors preserves structure and function of podocytes.
Journal of the American Society of Nephrology : JASN 2008;19(1):59-68.
2007: Yi Zhang; Bijoy Kundu; Karen D Fairchild; Landon Locke; Stuart S Berr; Joel Linden; Dongfeng Pan
Synthesis of novel neutrophil-specific imaging agents for Positron Emission Tomography (PET) imaging.
Bioorganic & medicinal chemistry letters 2007;17(24):6876-8.
2007: Adam N Clark; Rebecca Youkey; Xiaoping Liu; Liguo Jia; Rebecca J Blatt; Yuan-Ji Day; Gail W Sullivan; Joel Linden; Amy L Tucker
A1 adenosine receptor activation promotes angiogenesis and release of VEGF from monocytes.
Circulation research 2007;101(11):1130-8.
2007: Alison Gregg; Steven E Bottle; Shane M Devine; Heidi Figler; Joel Linden; Paul White; Colin W Pouton; Vijay Urmaliya; Peter J Scammells
Dual acting antioxidant A1 adenosine receptor agonists.
Bioorganic & medicinal chemistry letters 2007;17(19):5437-41.
2007: Jörg Reutershan; Rebecca E Cagnina; Daniel Chang; Joel Linden; Klaus Ley
Therapeutic anti-inflammatory effects of myeloid cell adenosine receptor A2a stimulation in lipopolysaccharide-induced lung injury.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(2):1254-63.
2007: David K Glover; Mirta Ruiz; Kazuya Takehana; Frank D Petruzella; Jayson M Rieger; Timothy L MacDonald; Denny Watson; Joel Linden; George A Beller
Cardioprotection by adenosine A2A agonists in a canine model of myocardial stunning produced by multiple episodes of transient ischemia.
American journal of physiology. Heart and circulatory physiology 2007;292(6):H3164-71.
2007: Charles P Sevigny; Li Li; Alaa S Awad; Liping Huang; Marcia McDuffie; Joel Linden; Peter I Lobo; Mark D Okusa
Activation of adenosine 2A receptors attenuates allograft rejection and alloantigen recognition.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(7):4240-9.
2006: Joel Linden
Cell biology. Purinergic chemotaxis.
Science (New York, N.Y.) 2006;314(5806):1689-90.
2006: Courtney M Lappas; Yuan-Ji Day; Melissa A Marshall; Victor H Engelhard; Joel Linden
Adenosine A2A receptor activation reduces hepatic ischemia reperfusion injury by inhibiting CD1d-dependent NKT cell activation.
The Journal of experimental medicine 2006;203(12):2639-48.
2006: Zequan Yang; Yuan-Ji Day; Marie-Claire Toufektsian; Yaqin Xu; Susan I Ramos; Melissa A Marshall; Brent A French; Joel Linden
Myocardial infarct-sparing effect of adenosine A2A receptor activation is due to its action on CD4+ T lymphocytes.
Circulation 2006;114(19):2056-64.
2006: William E McIntire; Gavin MacCleery; Lauren J Murphree; Kristi R Kerchner; Joel Linden; James C Garrison
Influence of differential stability of G protein βγ dimers containing the γ11 subunit on functional activity at the M1 muscarinic receptor, A1 adenosine receptor, and phospholipase C-β.
Biochemistry 2006;45(38):11616-31.
2006: Yuesheng Li; Rod J Oskouian; Yuan-Ji Day; Jayson M Rieger; L Liu; John A Kern; Joel Linden
Mouse spinal cord compression injury is reduced by either activation of the adenosine A2A receptor on bone marrow-derived cells or deletion of the A2A receptor on non-bone marrow-derived cells.
Neuroscience 2006;141(4):2029-39.
2006: Makoto Naganuma; Elizabeth B Wiznerowicz; Courtney M Lappas; Joel Linden; Mark Worthington; Peter B Ernst
Cutting edge: Critical role for A2A adenosine receptors in the T cell-mediated regulation of colitis.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(5):2765-9.
2006: T Brett Reece; Irving L Kron; David O Okonkwo; Jeffrey J Laurent; Carlos Tache-Leon; Thomas S Maxey; Peter I Ellman; Joel Linden; Curtis G Tribble; John A Kern
Functional and cytoarchitectural spinal cord protection by ATL-146e after ischemia/reperfusion is mediated by adenosine receptor agonism.
Journal of vascular surgery 2006;44(2):392-7.
2006: Joel Linden
New insights into the regulation of inflammation by adenosine.
The Journal of clinical investigation 2006;116(7):1835-7.
2006: Samita Bhattacharya; Rebecca L Youkey; Kobina Ghartey; Matthew Leonard; Joel Linden; Amy L Tucker
The allosteric enhancer PD81,723 increases chimaeric A1/A2A adenosine receptor coupling with Gs.
The Biochemical journal 2006;396(1):139-46.
2006: I C Cavalcante; M V Castro; A R F Barreto; Gail W Sullivan; Mariana L Vale; P R C Almeida; Joel Linden; Jayson M Rieger; Fernando Q Cunha; Richard L Guerrant; Ronaldo A Ribeiro; G A C Brito
Effect of novel A2A adenosine receptor agonist ATL 313 on Clostridium difficile toxin A-induced murine ileal enteritis.
Infection and immunity 2006;74(5):2606-12.
2006: Ran Zhu; Cynthia R Frazier; Joel Linden; Timothy L MacDonald
N6-ethyl-2-alkynyl NECAs, selective human A3 adenosine receptor agonists.
Bioorganic & medicinal chemistry letters 2006;16(9):2416-8.
2006: Alaa S Awad; Liping Huang; Hong Ye; Elizabeth Thu Anh Duong; W Kline Bolton; Joel Linden; Mark D Okusa
Adenosine A2A receptor activation attenuates inflammation and injury in diabetic nephropathy.
American journal of physiology. Renal physiology 2006;290(4):F828-37.
2006: George Nikolakopoulos; Heidi Figler; Joel Linden; Peter J Scammells
2-Aminothiophene-3-carboxylates and carboxamides as adenosine A1 receptor allosteric enhancers.
Bioorganic & medicinal chemistry 2006;14(7):2358-65.
2006: Marie-Claire Toufektsian; Zequan Yang; Prasad Konkalmatt; Lut Overbergh; Susan I Ramos; Chantal Mathieu; Joel Linden; Brent A French
Stimulation of A2A-adenosine receptors after myocardial infarction suppresses inflammatory activation and attenuates contractile dysfunction in the remote left ventricle.
American journal of physiology. Heart and circulatory physiology 2006;290(4):H1410-8.
2006: Yuan-Ji Day; Liping Huang; Hong Ye; Li Li; Joel Linden; Mark D Okusa
Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: the role of CD4+ T cells and IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(5):3108-14.
2006: T Brett Reece; David O Okonkwo; Peter I Ellman; Thomas S Maxey; Carlos Tache-Leon; Patrick S Warren; Jeffrey J Laurent; Joel Linden; Irving L Kron; Curtis G Tribble; John A Kern
Comparison of systemic and retrograde delivery of adenosine A2A agonist for attenuation of spinal cord injury after thoracic aortic cross-clamping.
The Annals of thoracic surgery 2006;81(3):902-9.
2006: Yuesheng Li; Rod J Oskouian; Yuan-Ji Day; John A Kern; Joel Linden
Optimization of a mouse locomotor rating system to evaluate compression-induced spinal cord injury: correlation of locomotor and morphological injury indices.
Journal of neurosurgery. Spine 2006;4(2):165-73.
2006: David O Okonkwo; T Brett Reece; Jeffrey J Laurent; A Stewart Hawkins; Peter I Ellman; Joel Linden; Irving L Kron; Curtis G Tribble; James R Stone; John A Kern
A comparison of adenosine A2A agonism and methylprednisolone in attenuating neuronal damage and improving functional outcome after experimental traumatic spinal cord injury in rabbits.
Journal of neurosurgery. Spine 2006;4(1):64-70.
2005: Lauren J Murphree; Gail W Sullivan; Melissa A Marshall; Joel Linden
Lipopolysaccharide rapidly modifies adenosine receptor transcripts in murine and human macrophages: role of NF-kappaB in A(2A) adenosine receptor induction.
The Biochemical journal 2005;391(Pt 3):575-80.
2005: Mahendra D Chordia; Molly A Zigler; Lauren J Murphree; Heidi Figler; Timothy L MacDonald; Ray A Olsson; Joel Linden
6-aryl-8H-indeno[1,2-d]thiazol-2-ylamines: A1 adenosine receptor agonist allosteric enhancers having improved potency.
Journal of medicinal chemistry 2005;48(16):5131-9.
2005: Courtney M Lappas; Gail W Sullivan; Joel Linden
Adenosine A2A agonists in development for the treatment of inflammation.
Expert opinion on investigational drugs 2005;14(7):797-806.
2005: Masaru Odashima; Giorgos Bamias; Jesús Rivera-Nieves; Joel Linden; Cynthia C Nast; Christopher A Moskaluk; Marco Marini; Kazuhiko Sugawara; Kosuke Kozaiwa; Michiro Otaka; Sumio Watanabe; Fabio Cominelli
Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel disease.
Gastroenterology 2005;129(1):26-33.
2005: Zequan Yang; Yuan-Ji Day; Marie-Claire Toufektsian; Susan I Ramos; Melissa Marshall; Xin-Qun Wang; Brent A French; Joel Linden
Infarct-sparing effect of A2A-adenosine receptor activation is due primarily to its action on lymphocytes.
Circulation 2005;111(17):2190-7.
2005: T Brett Reece; Peter I Ellman; Thomas S Maxey; Ivan K Crosby; Patrick S Warren; Tae W Chong; Robin D LeGallo; Joel Linden; John A Kern; Curtis G Tribble; Irving L Kron
Adenosine A2A receptor activation reduces inflammation and preserves pulmonary function in an in vivo model of lung transplantation.
The Journal of thoracic and cardiovascular surgery 2005;129(5):1137-43.
2005: Joel Linden
Adenosine in tissue protection and tissue regeneration.
Molecular pharmacology 2005;67(5):1385-7.
2005: Elena Bastia; Yue-Hang Xu; Angela C Scibelli; Yuan-Ji Day; Joel Linden; Jiang-Fan Chen; Michael A Schwarzschild
A crucial role for forebrain adenosine A(2A) receptors in amphetamine sensitization.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(5):891-900.
2005: Yuan-Ji Day; Yuesheng Li; Jayson M Rieger; Susan I Ramos; Mark D Okusa; Joel Linden
A2A adenosine receptors on bone marrow-derived cells protect liver from ischemia-reperfusion injury.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(8):5040-6.
2005: T Brett Reece; Victor E Laubach; Curtis G Tribble; Thomas S Maxey; Peter I Ellman; Patrick S Warren; Andrew M Schulman; Joel Linden; John A Kern; Irving L Kron
Adenosine A2A receptor agonist improves cardiac dysfunction from pulmonary ischemia-reperfusion injury.
The Annals of thoracic surgery 2005;79(4):1189-95.
2005: David K Glover; Laurent M Riou; Mirta Ruiz; Gail W Sullivan; Joel Linden; Jayson M Rieger; Timothy L MacDonald; Denny Watson; George A Beller
Reduction of infarct size and postischemic inflammation from ATL-146e, a highly selective adenosine A2A receptor agonist, in reperfused canine myocardium.
American journal of physiology. Heart and circulatory physiology 2005;288(4):H1851-8.
2005: Yuan-Ji Day; Liping Huang; Hong Ye; Joel Linden; Mark D Okusa
Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: role of macrophages.
American journal of physiology. Renal physiology 2005;288(4):F722-31.
2005: Courtney M Lappas; Jayson M Rieger; Joel Linden
A2A adenosine receptor induction inhibits IFN-gamma production in murine CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(2):1073-80.
2004: T Brett Reece; David O Okonkwo; Peter I Ellman; Patrick S Warren; Robert L Smith; A Stewart Hawkins; Joel Linden; Irving L Kron; Curtis G Tribble; John A Kern
The evolution of ischemic spinal cord injury in function, cytoarchitecture, and inflammation and the effects of adenosine A2A receptor activation.
The Journal of thoracic and cardiovascular surgery 2004;128(6):925-32.
2004: Song Ling; Yanling Wu; Jie Zheng; Joel Linden; Joseph Holoshitz
Genoprotective pathways. II. Attenuation of oxidative DNA damage by isopentenyl diphosphate.
Mutation research 2004;554(1-2):33-43.
2004: Sally A Hutchinson; Stephen P Baker; Joel Linden; Peter J Scammells
New potent and selective A1 adenosine receptor agonists.
Bioorganic & medicinal chemistry 2004;12(18):4877-84.
2004: T Brett Reece; Jonathan D Davis; David O Okonkwo; Thomas S Maxey; Peter I Ellman; Xinning Li; Joel Linden; Curtis G Tribble; Irving L Kron; John A Kern
Adenosine A2A analogue reduces long-term neurologic injury after blunt spinal trauma.
The Journal of surgical research 2004;121(1):130-4.
2004: Gail W Sullivan; Guodong Fang; Joel Linden; W Michael Scheld
A2A adenosine receptor activation improves survival in mouse models of endotoxemia and sepsis.
The Journal of infectious diseases 2004;189(10):1897-904.
2004: R Elaine Bucheimer; Joel Linden
Purinergic regulation of epithelial transport.
The Journal of physiology 2004;555(Pt 2):311-21.
2004: Yanling Wu; Jie Zheng; Joel Linden; Joseph Holoshitz
Genoprotective pathways. Part I. Extracellular signaling through G(s) protein-coupled adenosine receptors prevents oxidative DNA damage.
Mutation research 2004;546(1-2):93-102.
2004: Elizabeth Joshi; Mahendra D Chordia; Timothy L MacDonald; Joel Linden; Ray Olsson
Regioselective oxidation of 2-amino-3-aroyl-4,5-dialkylthiophenes by DMSO.
Bioorganic & medicinal chemistry letters 2004;14(4):929-33.
2004: Yuan-Ji Day; Melissa A Marshall; Liping Huang; Marcia McDuffie; Mark D Okusa; Joel Linden
Protection from ischemic liver injury by activation of A2A adenosine receptors during reperfusion: inhibition of chemokine induction.
American journal of physiology. Gastrointestinal and liver physiology 2004;286(2):G285-93.
2004: Gail W Sullivan; David D Lee; William G Ross; Jeffrey DiVietro; Courtney M Lappas; Michael B Lawrence; Joel Linden
Activation of A2A adenosine receptors inhibits expression of alpha 4/beta 1 integrin (very late antigen-4) on stimulated human neutrophils.
Journal of leukocyte biology 2004;75(1):127-34.
2003: Diane L Rosin; Barbara D Hettinger; Amy Lee; Joel Linden
Anatomy of adenosine A2A receptors in brain: morphological substrates for integration of striatal function.
Neurology 2003;61(11 Suppl 6):S12-8.
2003: Heidi Figler; Ray A Olsson; Joel Linden
Allosteric enhancers of A1 adenosine receptors increase receptor-G protein coupling and counteract Guanine nucleotide effects on agonist binding.
Molecular pharmacology 2003;64(6):1557-64.
2003: Claudia Benkwitz; James C Garrison; Joel Linden; Marcel E Durieux; Markus W Hollmann
Lidocaine enhances Galphai protein function.
Anesthesiology 2003;99(5):1093-101.
2003: Yuan-Ji Day; Liping Huang; Marcia McDuffie; Diane L Rosin; Hong Ye; Jiang-Fan Chen; Michael A Schwarzschild; J Stephen Fink; Joel Linden; Mark D Okusa
Renal protection from ischemia mediated by A2A adenosine receptors on bone marrow-derived cells.
The Journal of clinical investigation 2003;112(6):883-91.
2003: Dai-Trang E (Elizabeth) Le; Robert A Pelberg; Howard Leong-Poi; Jian-ping Bin; Joel Linden; Sanjiv Kaul
A1-receptor blockade: a novel approach for assessing myocardial viability in chronic ischemic cardiomyopathy.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2003;16(7):764-9.
2003: Steven H Platts; Joel Linden; Brian R Duling
Rapid modification of the glycocalyx caused by ischemia-reperfusion is inhibited by adenosine A2A receptor activation.
American journal of physiology. Heart and circulatory physiology 2003;284(6):H2360-7.
2003: Henning Lütjens; Andrea Zickgraf; Heidi Figler; Joel Linden; Ray A Olsson; Peter J Scammells
2-Amino-3-benzoylthiophene allosteric enhancers of A1 adenosine agonist binding: new 3, 4-, and 5-modifications.
Journal of medicinal chemistry 2003;46(10):1870-7.
2002: Laurent M Riou; Mirta Ruiz; Jayson M Rieger; Timothy L MacDonald; Denny Watson; Joel Linden; George A Beller; David K Glover
Influence of propranolol, enalaprilat, verapamil, and caffeine on adenosine A(2A)-receptor-mediated coronary vasodilation.
Journal of the American College of Cardiology 2002;40(9):1687-94.
2002: Steven M Fiser; Curtis G Tribble; Aditya K Kaza; Stewart M Long; John A Kern; David C Cassada; Joel Linden; Jayson Rieger; Victor E Laubach; Andy Matisoff; Irving L Kron
Adenosine A2A receptor activation decreases reperfusion injury associated with high-flow reperfusion.
The Journal of thoracic and cardiovascular surgery 2002;124(5):973-8.
2002: Joel Linden
Autoregulation of cyclic AMP in vascular smooth muscle: a role for adenosine receptors.
Molecular pharmacology 2002;62(5):969-70.
2002: David C Cassada; Curtis G Tribble; Stewart M Long; Aditya K Kaza; Joel Linden; Jayson M Rieger; Diane Rosin; Irving L Kron; John A Kern
Adenosine A2A agonist reduces paralysis after spinal cord ischemia: correlation with A2A receptor expression on motor neurons.
The Annals of thoracic surgery 2002;74(3):846-9; discussion 849-50.
2002: David C Cassada; Curtis G Tribble; Jeffrey S Young; James J Gangemi; A Reza Gohari; Paris D Butler; Jayson M Rieger; Irving L Kron; Joel Linden; John A Kern
Adenosine A2A analogue improves neurologic outcome after spinal cord trauma in the rabbit.
The Journal of trauma 2002;53(2):225-9; discussion 229-31.
2002: Laurent M Riou; Mirta Ruiz; Gail W Sullivan; Joel Linden; Howard Leong-Poi; Jonathan R Lindner; Thomas D Harris; George A Beller; David K Glover
Assessment of myocardial inflammation produced by experimental coronary occlusion and reperfusion with 99mTc-RP517, a new leukotriene B4 receptor antagonist that preferentially labels neutrophils in vivo.
Circulation 2002;106(5):592-8.
2002: Mahendra D Chordia; Lauren J Murphree; Timothy L MacDonald; Joel Linden; Ray A Olsson
2-Aminothiazoles: a new class of agonist allosteric enhancers of A(1) adenosine receptors.
Bioorganic & medicinal chemistry letters 2002;12(12):1563-6.
2002: David C Cassada; Curtis G Tribble; Stewart M Long; Victor E Laubach; Aditya K Kaza; Joel Linden; Bao-Ngoc Nguyen; Jayson M Rieger; Steven M Fiser; Irving L Kron; John A Kern
Adenosine A2A analogue ATL-146e reduces systemic tumor necrosing factor-alpha and spinal cord capillary platelet-endothelial cell adhesion molecule-1 expression after spinal cord ischemia.
Journal of vascular surgery 2002;35(5):994-8.
2002: Lauren J Murphree; Melissa A Marshall; Jayson M Rieger; Timothy L MacDonald; Joel Linden
Human A(2A) adenosine receptors: high-affinity agonist binding to receptor-G protein complexes containing Gbeta(4).
Molecular pharmacology 2002;61(2):455-62.
2002: C Elisabet Tranberg; Andrea Zickgraf; Brian N Giunta; Henning Luetjens; Heidi Figler; Lauren J Murphree; Ruediger Falke; Holger Fleischer; Joel Linden; Peter J Scammells; Ray A Olsson
2-Amino-3-aroyl-4,5-alkylthiophenes: agonist allosteric enhancers at human A(1) adenosine receptors.
Journal of medicinal chemistry 2002;45(2):382-9.
2001: David C Cassada; James J Gangemi; Jayson M Rieger; Joel Linden; Aditya K Kaza; Stewart M Long; Irving L Kron; Curtis G Tribble; John A Kern
Systemic adenosine A2A agonist ameliorates ischemic reperfusion injury in the rabbit spinal cord.
The Annals of thoracic surgery 2001;72(4):1245-50.
2001: Rachael J Cerniway; Zequan Yang; M A Jacobson; Joel Linden; G Paul Matherne
Targeted deletion of A(3) adenosine receptors improves tolerance to ischemia-reperfusion injury in mouse myocardium.
American journal of physiology. Heart and circulatory physiology 2001;281(4):H1751-8.
2001: David K Glover; Mirta Ruiz; Kazuya Takehana; Frank D Petruzella; Laurent M Riou; Jayson M Rieger; Timothy L MacDonald; Denny Watson; Joel Linden; George A Beller
Pharmacological stress myocardial perfusion imaging with the potent and selective A(2A) adenosine receptor agonists ATL193 and ATL146e administered by either intravenous infusion or bolus injection.
Circulation 2001;104(10):1181-7.
2001: David C Cassada; Curtis G Tribble; Victor E Laubach; B N Nguyen; Jayson M Rieger; Joel Linden; Aditya K Kaza; Stewart M Long; Irving L Kron; John A Kern
An adenosine A2A agonist, ATL-146e, reduces paralysis and apoptosis during rabbit spinal cord reperfusion.
Journal of vascular surgery 2001;34(3):482-8.
2001: David C Cassada; Curtis G Tribble; Aditya K Kaza; Steven M Fiser; Stewart M Long; Joel Linden; Jayson M Rieger; Irving L Kron; John A Kern
Adenosine analogue reduces spinal cord reperfusion injury in a time-dependent fashion.
Surgery 2001;130(2):230-5.
2001: Shayn M Peirce; Thomas C Skalak; Jayson M Rieger; Timothy L MacDonald; Joel Linden
Selective A(2A) adenosine receptor activation reduces skin pressure ulcer formation and inflammation.
American journal of physiology. Heart and circulatory physiology 2001;281(1):H67-74.
2001: Mark D Okusa; Joel Linden; Liping Huang; Diane L Rosin; D F Smith; G Sullivan
Enhanced protection from renal ischemia-reperfusion [correction of ischemia:reperfusion] injury with A(2A)-adenosine receptor activation and PDE 4 inhibition.
Kidney international 2001;59(6):2114-25.
2001: John A McPherson; Kurt G Barringhaus; Gregory G Bishop; John M Sanders; Jayson M Rieger; sean hesselbacher; Lawrence W Gimple; Eric Randall Powers; Timothy Macdonald; G Sullivan; Joel Linden; Ian J Sarembock
Adenosine A(2A) receptor stimulation reduces inflammation and neointimal growth in a murine carotid ligation model.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(5):791-6.
2001: Barbara D Hettinger; Amy Lee; Joel Linden; Diane L Rosin
Ultrastructural localization of adenosine A2A receptors suggests multiple cellular sites for modulation of GABAergic neurons in rat striatum.
The Journal of comparative neurology 2001;431(3):331-46.
2001: Gail W Sullivan; Jayson M Rieger; W Michael Scheld; Timothy L MacDonald; Joel Linden
Cyclic AMP-dependent inhibition of human neutrophil oxidative activity by substituted 2-propynylcyclohexyl adenosine A(2A) receptor agonists.
British journal of pharmacology 2001;132(5):1017-26.
2001: Jayson M Rieger; Milton L Brown; Gail W Sullivan; Joel Linden; Timothy L MacDonald
Design, synthesis, and evaluation of novel A2A adenosine receptor agonists.
Journal of medicinal chemistry 2001;44(4):531-9.
2001: Joel Linden
Molecular approach to adenosine receptors: receptor-mediated mechanisms of tissue protection.
Annual review of pharmacology and toxicology 2001;41():775-87.
2001: Z Gao; B S Li; Yuan-Ji Day; Joel Linden
A3 adenosine receptor activation triggers phosphorylation of protein kinase B and protects rat basophilic leukemia 2H3 mast cells from apoptosis.
Molecular pharmacology 2001;59(1):76-82.
2000: Amy L Tucker; Li-Guo Jia; D Holeton; A J Taylor; Joel Linden
Dominance of G(s) in doubly G(s)/G(i)-coupled chimaeric A(1)/A(2A) adenosine receptors in HEK-293 cells.
The Biochemical journal 2000;352 Pt 1():203-10.
2000: Mark D Okusa; Joel Linden; Liping Huang; Jayson M Rieger; Timothy L MacDonald; L P Huynh
A(2A) adenosine receptor-mediated inhibition of renal injury and neutrophil adhesion.
American journal of physiology. Renal physiology 2000;279(5):F809-18.
2000: Gail W Sullivan; I J Sarembock; Joel Linden
The role of inflammation in vascular diseases.
Journal of leukocyte biology 2000;67(5):591-602.
2000: Michael Fenster; R K Shepherd; Joel Linden; Brian R Duling
Activation of adenosine A2 alpha receptors inhibits mast cell degranulation and mast cell-dependent vasoconstriction.
Microcirculation (New York, N.Y. : 1994) 2000;7(2):129-35.
1999: Gail W Sullivan; Joel Linden; B L Buster; W Michael Scheld
Neutrophil A2A adenosine receptor inhibits inflammation in a rat model of meningitis: synergy with the type IV phosphodiesterase inhibitor, rolipram.
The Journal of infectious diseases 1999;180(5):1550-60.
1999: SD Ross; Curtis G Tribble; Joel Linden; James J Gangemi; B C Lanpher; A Y Wang; Irving L Kron
Selective adenosine-A2A activation reduces lung reperfusion injury following transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 1999;18(10):994-1002.
1999: Joel Linden; To Thai; Heidi Figler; Xiaowei Jin; AS Robeva
Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells.
Molecular pharmacology 1999;56(4):705-13.
1999: Mark D Okusa; Joel Linden; Timothy Macdonald; Liping Huang
Selective A2A adenosine receptor activation reduces ischemia-reperfusion injury in rat kidney.
The American journal of physiology 1999;277(3 Pt 2):F404-12.
1999: Z Gao; Y Ni; G Szabo; Joel Linden
Palmitoylation of the recombinant human A1 adenosine receptor: enhanced proteolysis of palmitoylation-deficient mutant receptors.
The Biochemical journal 1999;342 ( Pt 2)():387-95.
1999: Z Gao; AS Robeva; Joel Linden
Purification of A1 adenosine receptor-G-protein complexes: effects of receptor down-regulation and phosphorylation on coupling.
The Biochemical journal 1999;338 ( Pt 3)():729-36.
1999: Z Gao; T Chen; Michael J Weber; Joel Linden
A2B adenosine and P2Y2 receptors stimulate mitogen-activated protein kinase in human embryonic kidney-293 cells. cross-talk between cyclic AMP and protein kinase c pathways.
The Journal of biological chemistry 1999;274(9):5972-80.
1998: Diane L Rosin; AS Robeva; R L Woodard; Patrice G Guyenet; Joel Linden
Immunohistochemical localization of adenosine A2A receptors in the rat central nervous system.
The Journal of comparative neurology 1998;401(2):163-86.
1998: Joel Linden; John A Auchampach; Xiaowei Jin; Robert A Figler
The structure and function of A1 and A2B adenosine receptors.
Life sciences 1998;62(17-18):1519-24.
1997: Robert A Figler; Margaret A Lindorfer; S G Graber; James C Garrison; Joel Linden
Reconstitution of bovine A1 adenosine receptors and G proteins in phospholipid vesicles: betagamma-subunit composition influences guanine nucleotide exchange and agonist binding.
Biochemistry 1997;36(51):16288-99.
1997: Xiaowei Jin; R K Shepherd; Brian R Duling; Joel Linden
Inosine binds to A3 adenosine receptors and stimulates mast cell degranulation.
The Journal of clinical investigation 1997;100(11):2849-57.
1997: John A Auchampach; Xiaowei Jin; Tina C Wan; George H Caughey; Joel Linden
Canine mast cell adenosine receptors: cloning and expression of the A3 receptor and evidence that degranulation is mediated by the A2B receptor.
Molecular pharmacology 1997;52(5):846-60.
1997: G Paul Matherne; Joel Linden; Anne M Byford; NS Gauthier; John P Headrick
Transgenic A1 adenosine receptor overexpression increases myocardial resistance to ischemia.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(12):6541-6.
1997: Michael Fenster; Marc D Feldman; G Camarano; W H Johnson; M Ellis; Joel Linden; George A Beller
Correlation of adenosine thallium 201 perfusion patterns with markers for inducible ischemia.
American heart journal 1997;133(4):406-12.
1996: Robert A Figler; Stephen G Graber; Margaret A Lindorfer; H Yasuda; Joel Linden; James C Garrison
Reconstitution of recombinant bovine A1 adenosine receptors in Sf9 cell membranes with recombinant G proteins of defined composition.
Molecular pharmacology 1996;50(6):1587-95.
1996: H K Lu; R J Fern; D Luthin; Joel Linden; L P Liu; C J Cohen; Paula Q Barrett
Angiotensin II stimulates T-type Ca2+ channel currents via activation of a G protein, Gi.
The American journal of physiology 1996;271(4 Pt 1):C1340-9.
1996: A P Kennedy; K C Mangum; Joel Linden; J N Wells
Covalent modification of transmembrane span III of the A1 adenosine receptor with an antagonist photoaffinity probe.
Molecular pharmacology 1996;50(4):789-98.
1996: S Bhattacharya; Joel Linden
Effects of long-term treatment with the allosteric enhancer, PD81,723, on Chinese hamster ovary cells expressing recombinant human A1 adenosine receptors.
Molecular pharmacology 1996;50(1):104-11.
1996: R K Shepherd; Joel Linden; Brian R Duling
Adenosine-induced vasoconstriction in vivo. Role of the mast cell and A3 adenosine receptor.
Circulation research 1996;78(4):627-34.
1996: A S Robeva; R Woodard; D R Luthin; H E Taylor; Joel Linden
Double tagging recombinant A1- and A2A-adenosine receptors with hexahistidine and the FLAG epitope. Development of an efficient generic protein purification procedure.
Biochemical pharmacology 1996;51(4):545-55.
1995: D R Luthin; Kung-Shing Lee; D Okonkwo; P Zhang; Joel Linden
Photoaffinity labeling with 2(-)[2-(4-azido-3(-)[125I]- iodophenyl)ethylamino]adenosine and autoradiography with 2(-)[2-(4-amino-3(-)[125I]iodophenyl)ethylamino]adenosine of A2a adenosine receptors in rat brain.
Journal of neurochemistry 1995;65(5):2072-9.
1995: Deborah A Berkich; D R Luthin; R L Woodard; Susan J Vannucci; Joel Linden; Kathryn F Lanoue
Evidence for regulated coupling of A1 adenosine receptors by phosphorylation in Zucker rats.
The American journal of physiology 1995;268(4 Pt 1):E693-704.
1995: S Bhattacharya; Joel Linden
The allosteric enhancer, PD 81,723, stabilizes human A1 adenosine receptor coupling to G proteins.
Biochimica et biophysica acta 1995;1265(1):15-21.
1995: D R Luthin; R A Olsson; R D Thompson; D R Sawmiller; Joel Linden
Characterization of two affinity states of adenosine A2a receptors with a new radioligand, 2-[2-(4-amino-3-[125I]iodophenyl)ethylamino]adenosine.
Molecular pharmacology 1995;47(2):307-13.
1995: D R Luthin; Joel Linden
Comparison of A4 and A2a binding sites in striatum and COS cells transfected with adenosine A2a receptors.
The Journal of pharmacology and experimental therapeutics 1995;272(2):511-8.
1995: D L Cothran; Thomas R Lloyd; H Taylor; Joel Linden; G Paul Matherne
Ontogeny of rat myocardial A1 adenosine receptors.
Biology of the neonate 1995;68(2):111-8.
1994: A L Tucker; A S Robeva; H E Taylor; D Holeton; M Bockner; Kevin R Lynch; Joel Linden
A1 adenosine receptors. Two amino acids are responsible for species differences in ligand recognition.
The Journal of biological chemistry 1994;269(45):27900-6.
1994: Joel Linden
Cloned adenosine A3 receptors: pharmacological properties, species differences and receptor functions.
Trends in pharmacological sciences 1994;15(8):298-306.
1994: D P McLaughlin; George A Beller; Joel Linden; C R Ayers; M L Ripley; H Taylor; Denny Watson; Marc D Feldman
Hemodynamic and metabolic correlates of dipyridamole-induced myocardial thallium-201 perfusion abnormalities in multivessel coronary artery disease.
The American journal of cardiology 1994;73(16):1159-64.
1994: M P Doyle; Joel Linden; Brian R Duling
Nucleoside-induced arteriolar constriction: a mast cell-dependent response.
The American journal of physiology 1994;266(5 Pt 2):H2042-50.
1994: D R Sawmiller; Joel Linden; R M Berne
Effects of xanthine amine congener on hypoxic coronary resistance and venous and epicardial adenosine concentrations.
Cardiovascular research 1994;28(5):604-9.
1993: C M Eppler; J D Hulmes; Jia Bei Wang; B Johnson; M Corbett; D R Luthin; George R. Uhl; Joel Linden
Purification and partial amino acid sequence of a mu opioid receptor from rat brain.
The Journal of biological chemistry 1993;268(35):26447-51.
1993: Joel Linden; H E Taylor; A S Robeva; A L Tucker; J H Stehle; S A Rivkees; J Stephen Fink; Steven M Reppert
Molecular cloning and functional expression of a sheep A3 adenosine receptor with widespread tissue distribution.
Molecular pharmacology 1993;44(3):524-32.
1993: D R Luthin; C M Eppler; Joel Linden
Identification and quantification of Gi-type GTP-binding proteins that copurify with a pituitary somatostatin receptor.
The Journal of biological chemistry 1993;268(8):5990-6.
1993: A L Tucker; Joel Linden
Cloned receptors and cardiovascular responses to adenosine.
Cardiovascular research 1993;27(1):62-7.
1992: J K Crane; M S Wehner; E J Bolen; Julianne J Sando; Joel Linden; Richard L Guerrant; Cynthia L Sears
Regulation of intestinal guanylate cyclase by the heat-stable enterotoxin of Escherichia coli (STa) and protein kinase C.
Infection and immunity 1992;60(12):5004-12.
1992: M R Prater; H Taylor; R Munshi; Joel Linden
Indirect effect of guanine nucleotides on antagonist binding to A1 adenosine receptors: occupation of cryptic binding sites by endogenous vesicular adenosine.
Molecular pharmacology 1992;42(5):765-72.
1992: Joel Linden; H E Taylor; Marc D Feldman; E B Woodward; C R Ayers; M L Ripley; S Iflah; A Patel
The precise radioimmunoassay of adenosine: minimization of sample collection artifacts and immunocrossreactivity.
Analytical biochemistry 1992;201(2):246-54.
1992: A L Tucker; Joel Linden; A S Robeva; D D D'Angelo; Kevin R Lynch
Cloning and expression of a bovine adenosine A1 receptor cDNA.
FEBS letters 1992;297(1-2):107-11.
1992: Marc D Feldman; C R Ayers; M R Lehman; H E Taylor; V L Gordon; P J Sabia; D Ras; Thomas C Skalak; Joel Linden
Improved detection of ischemia-induced increases in coronary sinus adenosine in patients with coronary artery disease.
Clinical chemistry 1992;38(2):256-62.
1991: R Munshi; Iok-Hou Pang; Paul C Sternweis; Joel Linden
A1 adenosine receptors of bovine brain couple to guanine nucleotide-binding proteins Gi1, Gi2, and Go.
The Journal of biological chemistry 1991;266(33):22285-9.
1991: Joel Linden; A L Tucker; Kevin R Lynch
Molecular cloning of adenosine A1 and A2 receptors.
Trends in pharmacological sciences 1991;12(9):326-8.
1991: Joel Linden
Structure and function of A1 adenosine receptors.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1991;5(12):2668-76.
1991: Z Friedman; T M Delahunty; Joel Linden; Peter A Campochiaro
Human retinal pigment epithelial cells possess V1 vasopressin receptors.
Current eye research 1991;10(9):811-6.
1991: Robert L Chevalier; M Garmey; R M Scarborough; Joel Linden; R Ariel Gomez; M J Peach; Robert M Carey
Inhibition of ANP clearance receptors and endopeptidase 24.11 in maturing rats.
The American journal of physiology 1991;260(6 Pt 2):R1218-28.
1991: Christopher M Rembold; B A Weaver; Joel Linden
Adenosine triphosphate induces a low [Ca2+]i sensitivity of phosphorylation and an unusual form of receptor desensitization in smooth muscle.
The Journal of biological chemistry 1991;266(9):5407-11.
1991: Joel Linden; M R Prater; G W Sullivan; Roger Johns; A Patel
Contamination of adenosine deaminase by superoxide dismutase. Stabilization of endothelium-derived relaxing factor.
Biochemical pharmacology 1991;41(2):273-9.
1990: Lazar J Greenfield; John T Hackett; Joel Linden
Xenopus oocyte K+ current. II. Adenylyl cyclase-linked receptors on follicle cells.
The American journal of physiology 1990;259(5 Pt 1):C784-91.
1990: Lazar J Greenfield; John T Hackett; Joel Linden
Xenopus oocyte K+ current. I. FSH and adenosine stimulate follicle cell-dependent currents.
The American journal of physiology 1990;259(5 Pt 1):C775-83.
1990: Lazar J Greenfield; John T Hackett; Joel Linden
Xenopus oocyte K+ current. III. Phorbol esters and pH regulate current at gap junctions.
The American journal of physiology 1990;259(5 Pt 1):C792-800.
1990: Roger Johns; M J Peach; Joel Linden; A Tichotsky
NG-monomethyl L-arginine inhibits endothelium-derived relaxing factor-stimulated cyclic GMP accumulation in cocultures of endothelial and vascular smooth muscle cells by an action specific to the endothelial cell.
Circulation research 1990;67(4):979-85.
1990: G W Sullivan; Joel Linden; Erik L Hewlett; H T Carper; John B Hylton; Gerald L Mandell
Adenosine and related compounds counteract tumor necrosis factor-alpha inhibition of neutrophil migration: implication of a novel cyclic AMP-independent action on the cell surface.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(5):1537-44.
1990: R Munshi; Joel Linden
Interaction of purified bovine brain A1-adenosine receptors with guanine nucleotide-binding proteins of human platelet membranes following reconstitution.
Molecular pharmacology 1990;38(2):170-6.
1990: C S Weikel; C L Spann; C P Chambers; J K Crane; Joel Linden; Erik L Hewlett
Phorbol esters enhance the cyclic GMP response of T84 cells to the heat-stable enterotoxin of Escherichia coli (STa).
Infection and immunity 1990;58(5):1402-7.
1990: Ross Tracey; Joel Linden; M J Peach; Roger Johns
Comparison of spectrophotometric and biological assays for nitric oxide (NO) and endothelium-derived relaxing factor (EDRF): nonspecificity of the diazotization reaction for NO and failure to detect EDRF.
The Journal of pharmacology and experimental therapeutics 1990;252(3):922-8.
1989: R Munshi; Joel Linden
Co-purification of A1 adenosine receptors and guanine nucleotide-binding proteins from bovine brain.
The Journal of biological chemistry 1989;264(25):14853-9.
1989: Z Friedman; Sean F Hackett; Joel Linden; Peter A Campochiaro
Human retinal pigment epithelial cells in culture possess A2-adenosine receptors.
Brain research 1989;492(1-2):29-35.
1988: T M Delahunty; M J Cronin; Joel Linden
Regulation of GH3-cell function via adenosine A1 receptors. Inhibition of prolactin release, cyclic AMP production and inositol phosphate generation.
The Biochemical journal 1988;255(1):69-77.
1988: A Patel; R H Craig; S M Daluge; Joel Linden
125I-BW-A844U, an antagonist radioligand with high affinity and selectivity for adenosine A1 receptors, and 125I-azido-BW-A844U, a photoaffinity label.
Molecular pharmacology 1988;33(6):585-91.
1988: C Q Earl; A Patel; R H Craig; S M Daluge; Joel Linden
Photoaffinity labeling adenosine A1 receptors with an antagonist 125I-labeled aryl azide derivative of 8-phenylxanthine.
Journal of medicinal chemistry 1988;31(4):752-6.
1988: Joel Linden; A Patel; C Q Earl; R H Craig; S M Daluge
125I-labeled 8-phenylxanthine derivatives: antagonist radioligands for adenosine A1 receptors.
Journal of medicinal chemistry 1988;31(4):745-51.
1988: A Patel; Joel Linden
Purification of 125I-labeled succinyl cyclic nucleotide tyrosine methyl esters by high-performance liquid chromatography.
Analytical biochemistry 1988;168(2):417-20.