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Erin Linehan

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Anna J Ucher; George W Teebor; Erin K Linehan; Carol E Schrader; Janet Stavnezer
The DNA glycosylases Ogg1 and Nth1 do not contribute to Ig class switching in activated mouse splenic B cells.
Sanjay Ranjit; Carol E Schrader; Mrinmay Chakrabarti; Lyne Khair; Erin K Linehan; Anna J Ucher; Janet Stavnezer
AID binds cooperatively with UNG and Msh2-Msh6 to Ig switch regions dependent upon the AID C terminus.
Jeroen E J Guikema; Rachel M Gerstein; Erin K Linehan; Erin K Cloherty; Eric Evan-Browning; Daisuke Tsuchimoto; Yusaku Nakabeppu; Carol E Schrader
Apurinic/apyrimidinic endonuclease 2 is necessary for normal B cell development and recovery of lymphoid progenitors after chemotherapeutic challenge.

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All Publications

2012: Anna J Ucher; George W Teebor; Erin K Linehan; Carol E Schrader; Janet Stavnezer
The DNA glycosylases Ogg1 and Nth1 do not contribute to Ig class switching in activated mouse splenic B cells.
PloS one 2012;7(4):e36061.
2011: Sanjay Ranjit; Carol E Schrader; Mrinmay Chakrabarti; Lyne Khair; Erin K Linehan; Anna J Ucher; Janet Stavnezer
AID binds cooperatively with UNG and Msh2-Msh6 to Ig switch regions dependent upon the AID C terminus.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(5):2464-75.
2011: Jeroen E J Guikema; Rachel M Gerstein; Erin K Linehan; Erin K Cloherty; Eric Evan-Browning; Daisuke Tsuchimoto; Yusaku Nakabeppu; Carol E Schrader
Apurinic/apyrimidinic endonuclease 2 is necessary for normal B cell development and recovery of lymphoid progenitors after chemotherapeutic challenge.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(4):1943-50.
2010: Jeroen E J Guikema; Carol E Schrader; Michael H Brodsky; Erin K Linehan; Adam Richards; Nahla El Falaky; Daniel H Li; Hayla K Sluss; Eva Szomolanyi-Tsuda; Janet Stavnezer
p53 represses class switch recombination to IgG2a through its antioxidant function.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(11):6177-87.
2008: Jeroen E J Guikema; Carol E Schrader; Niek G J Leus; Anna Ucher; Erin K Linehan; Uwe Werling; Winfried Edelmann; Janet Stavnezer
Reassessment of the role of Mut S homolog 5 in Ig class switch recombination shows lack of involvement in cis- and trans-switching.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(12):8450-9.
2007: Jeroen Guikema; Erin K Linehan; Daisuke Tsuchimoto; Yusaku Nakabeppu; Phyllis R Strauss; Janet Stavnezer; Carol E Schrader
APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination.
The Journal of experimental medicine 2007;204(12):3017-26.
2007: Carol E Schrader; Jeroen Guikema; Erin K Linehan; Erik Selsing; Janet Stavnezer
Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(9):6064-71.
2005: Carol E Schrader; Erin K Linehan; Sofia N Mochegova; Robert T Woodland; Janet Stavnezer
Inducible DNA breaks in Ig S regions are dependent on AID and UNG.
The Journal of experimental medicine 2005;202(4):561-8.
2004: Carol E Schrader; Joycelyn Vardo; Erin K Linehan; Michael Z Twarog; Laura J Niedernhofer; Jan H J Hoeijmakers; Janet Stavnezer
Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions.
The Journal of experimental medicine 2004;200(3):321-30.