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Gabriela Link

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Anna Golubitzky; Gabriela Link; Sarah Weissman; Jakob D Wikstrom; Phyllis Dan; Ann Saada (Reisch)
Screening for active small molecules in mitochondrial complex I deficient patient's fibroblasts, reveals AICAR as the most beneficial compound.
Zvi Ackerman; Mor Oron-Herman; Talma Rosenthal; Orit Pappo; Gabriela Link; Ben-Ami Sela; Maria Grozovski
Effects of amlodipine, captopril, and bezafibrate on oxidative milieu in rats with fatty liver.
Joseph M Leimberg; Eugenia Prus; Gabriela Link; Eitan Fibach; Abraham M Konijn
Iron-chelator complexes as iron sources for early developing human erythroid precursors.

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All Publications

2011: Anna Golubitzky; Gabriela Link; Sarah Weissman; Jakob D Wikstrom; Phyllis Dan; Ann Saada (Reisch)
Screening for active small molecules in mitochondrial complex I deficient patient's fibroblasts, reveals AICAR as the most beneficial compound.
PloS one 2011;6(10):e26883.
2008: Zvi Ackerman; Mor Oron-Herman; Talma Rosenthal; Orit Pappo; Gabriela Link; Ben-Ami Sela; Maria Grozovski
Effects of amlodipine, captopril, and bezafibrate on oxidative milieu in rats with fatty liver.
Digestive diseases and sciences 2008;53(3):777-84.
2008: Joseph M Leimberg; Eugenia Prus; Gabriela Link; Eitan Fibach; Abraham M Konijn
Iron-chelator complexes as iron sources for early developing human erythroid precursors.
Translational research : the journal of laboratory and clinical medicine 2008;151(2):88-96.
2007: Yossi Dagon; Yosefa Avraham; Gabriela Link; Olga Zolotarev; Urij Rampampam; Elliot M Berry
The synthetic cannabinoid HU-210 attenuates neural damage in diabetic mice and hyperglycemic pheochromocytoma PC12 cells.
Neurobiology of disease 2007;27(2):174-81.
2006: Hava Glickstein; Rinat Ben El; Gabriela Link; William Breuer; Abraham M Konijn; Chaim Hershko; Hanspeter Nick; Ioav Cabantchik
Action of chelators in iron-loaded cardiac cells: Accessibility to intracellular labile iron and functional consequences.
Blood 2006;108(9):3195-203.
2006: Gil Peretz; Gabriela Link; Orit Pappo; Rafael Bruck; Zvi Ackerman
Effect of hepatic iron concentration reduction on hepatic fibrosis and damage in rats with cholestatic liver disease.
World journal of gastroenterology : WJG 2006;12(2):240-5.
2005: Zvi Ackerman; Mor Oron-Herman; Maria Grozovski; Talma Rosenthal; Orit Pappo; Gabriela Link; Ben-Ami Sela
Fructose-induced fatty liver disease: hepatic effects of blood pressure and plasma triglyceride reduction.
Hypertension 2005;45(5):1012-8.
2005: Chaim Hershko; Gabriela Link; Abraham M Konijn; Ioav Cabantchik
Iron chelation therapy.
Current hematology reports 2005;4(2):110-6.
2005: Chaim Hershko; Gabriela Link; Abraham M Konijn; Ioav Cabantchik
Objectives and mechanism of iron chelation therapy.
Annals of the New York Academy of Sciences 2005;1054():124-35.
2005: Chaim Hershko; Gabriela Link; Abraham M Konijn; Z Ioav Cabantchik
Iron overload and chelation.
Hematology (Amsterdam, Netherlands) 2005;10 Suppl 1():171-3.
2003: Gabriela Link; Prem Ponka; Abraham M Konijn; William Breuer; Ioav Cabantchik; Chaim Hershko
Effects of combined chelation treatment with pyridoxal isonicotinoyl hydrazone analogs and deferoxamine in hypertransfused rats and in iron-loaded rat heart cells.
Blood 2003;101(10):4172-9.
2003: Chaim Hershko; Aya Abrahamov; Abraham M Konijn; William Breuer; Ioav Zeev Cabantchik; Pensri Pootrakul; Gabriela Link
Objectives and methods of iron chelation therapy.
Bioinorganic chemistry and applications 2003;():151-68.
2002: Chaim Hershko; Gabriela Link; Abraham M Konijn
Cardioprotective effect of iron chelators.
Advances in experimental medicine and biology 2002;509():77-89.
2002: Chaim Hershko; Gabriela Link; Abraham M Konijn; M Huerta; Eliezer Rosenmann; Constantin Reinus
The iron-loaded gerbil model revisited: effects of deferoxamine and deferiprone treatment.
The Journal of laboratory and clinical medicine 2002;139(1):50-8.
2001: Gabriela Link; Abraham M Konijn; William Breuer; Ioav Cabantchik; Chaim Hershko
Exploring the "iron shuttle" hypothesis in chelation therapy: effects of combined deferoxamine and deferiprone treatment in hypertransfused rats with labeled iron stores and in iron-loaded rat heart cells in culture.
The Journal of laboratory and clinical medicine 2001;138(2):130-8.
2001: Chaim Hershko; Abraham M Konijn; H P Nick; William Breuer; Ioav Cabantchik; Gabriela Link
ICL670A: a new synthetic oral chelator: evaluation in hypertransfused rats with selective radioiron probes of hepatocellular and reticuloendothelial iron stores and in iron-loaded rat heart cells in culture.
Blood 2001;97(4):1115-22.
2000: Ann Saada (Reisch); I Aptowitzer; Gabriela Link; Orly Elpeleg
ATP synthesis in lipoamide dehydrogenase deficiency.
Biochemical and biophysical research communications 2000;269(2):382-6.
1999: Gabriela Link; Abraham M Konijn; Chaim Hershko
Cardioprotective effect of alpha-tocopherol, ascorbate, deferoxamine, and deferiprone: mitochondrial function in cultured, iron-loaded heart cells.
The Journal of laboratory and clinical medicine 1999;133(2):179-88.
1998: Chaim Hershko; Gabriela Link; Ioav Zeev Cabantchik
Pathophysiology of iron overload.
Annals of the New York Academy of Sciences 1998;850():191-201.
1998: Chaim Hershko; Abraham M Konijn; Gabriela Link
Iron chelators for thalassaemia.
British journal of haematology 1998;101(3):399-406.
1998: Gabriela Link; Ann Saada (Reisch); A Pinson; Abraham M Konijn; Chaim Hershko
Mitochondrial respiratory enzymes are a major target of iron toxicity in rat heart cells.
The Journal of laboratory and clinical medicine 1998;131(5):466-74.
1997: G Rivkin; Gabriela Link; E Simhon; R L Cyjon; J Y Klein; Chaim Hershko
IRC011, a new synthetic chelator with selective interaction with catabolic red blood cell iron: evaluation in hypertransfused rats with hepatocellular and reticuloendothelial radioiron probes and in iron-loaded rat heart cells in culture.
Blood 1997;90(10):4180-7.
1997: I Halili-Rutman; Chaim Hershko; Gabriela Link; A J Rutman; Asher Shainberg
Inhibition of calcium accumulation by the sarcoplasmic reticulum: a putative mechanism for the cardiotoxicity of adriamycin.
Biochemical pharmacology 1997;54(1):211-4.
1996: Gabriela Link; R Tirosh; A Pinson; Chaim Hershko
Role of iron in the potentiation of anthracycline cardiotoxicity: identification of heart cell mitochondria as a major site of iron-anthracycline interaction.
The Journal of laboratory and clinical medicine 1996;127(3):272-8.
1996: Chaim Hershko; A Pinson; Gabriela Link
Prevention of anthracycline cardiotoxicity by iron chelation.
Acta haematologica 1996;95(1):87-92.
1994: Gabriela Link; A Pinson; Chaim Hershko
Ability of the orally effective iron chelators dimethyl- and diethyl-hydroxypyrid-4-one and of deferoxamine to restore sarcolemmal thiolic enzyme activity in iron-loaded heart cells.
Blood 1994;83(9):2692-7.
1994: Gabriela Link; A Pinson; Chaim Hershko
Identification of thiolic sarcolemmal proteins as a primary target of iron toxicity in cultured heart cells.
Advances in experimental medicine and biology 1994;356():267-76.
1993: Chaim Hershko; Gabriela Link; M Tzahor; A Pinson
The role of iron and iron chelators in anthracycline cardiotoxicity.
Leukemia & lymphoma 1993;11(3-4):207-14.
1993: Chaim Hershko; Gabriela Link; M Tzahor; J P Kaltwasser; Pierre Athias; Alain Grynberg; A Pinson
Anthracycline toxicity is potentiated by iron and inhibited by deferoxamine: studies in rat heart cells in culture.
The Journal of laboratory and clinical medicine 1993;122(3):245-51.
1993: Gabriela Link; A Pinson; Chaim Hershko
Iron loading of cultured cardiac myocytes modifies sarcolemmal structure and increases lysosomal fragility.
The Journal of laboratory and clinical medicine 1993;121(1):127-34.
1992: S Zevin; Gabriela Link; R W Grady; R C Hider; H H Peter; Chaim Hershko
Origin and fate of iron mobilized by the 3-hydroxypyridin-4-one oral chelators: studies in hypertransfused rats by selective radioiron probes of reticuloendothelial and hepatocellular iron stores.
Blood 1992;79(1):248-53.
1991: Gabriela Link; Pierre Athias; Alain Grynberg; Chaim Hershko; A Pinson
Iron loading modifies beta-adrenergic responsiveness in cultured ventricular myocytes.
Cardioscience 1991;2(3):185-8.
1991: Chaim Hershko; Gabriela Link; A Pinson; H H Peter; P Dobbin; R C Hider
Iron mobilization from myocardial cells by 3-hydroxypyridin-4-one chelators: studies in rat heart cells in culture.
Blood 1991;77(9):2049-53.
1990: Chaim Hershko; Gabriela Link; A Pinson
Principles of iron chelating therapy.
Seminars in hematology 1990;27(2):91-4.
1990: Chaim Hershko; A Pinson; Gabriela Link
Iron chelation.
Blood reviews 1990;4(1):1-8.
1990: Chaim Hershko; Gabriela Link; A Pinson; S Avramovici-Grisaru; S Sarel; H H Peter; R C Hider; R W Grady
New orally effective iron chelators. Animal studies.
Annals of the New York Academy of Sciences 1990;612():351-60.
1989: Gabriela Link; A Pinson; I Kahane; Chaim Hershko
Iron loading modifies the fatty acid composition of cultured rat myocardial cells and liposomal vesicles: effect of ascorbate and alpha-tocopherol on myocardial lipid peroxidation.
The Journal of laboratory and clinical medicine 1989;114(3):243-9.
1989: Gabriela Link; Pierre Athias; Alain Grynberg; A Pinson; Chaim Hershko
Effect of iron loading on transmembrane potential, contraction, and automaticity of rat ventricular muscle cells in culture.
The Journal of laboratory and clinical medicine 1989;113(1):103-11.
1988: Amos M Yinnon; A M Konijn; Gabriela Link; J Moreb; Chaim Hershko
Diagnostic value of ferritin in malignant pleural and peritoneal effusions.
Cancer 1988;62(12):2564-8.
1985: Chaim Hershko; A M Konijn; Gabriela Link; J Moreb; F Grauer; E Weissenberg
Combined use of zinc protoporphyrin (ZPP), mean corpuscular volume and haemoglobin measurements for classifying microcytic RBC disorders in children and young adults.
Clinical and laboratory haematology 1985;7(3):259-69.
1984: Chaim Hershko; A M Konijn; J Moreb; Gabriela Link; F Grauer; E Weissenberg
Iron depletion and blood lead levels in a population with endemic lead poisoning.
Israel journal of medical sciences 1984;20(11):1039-43.
1983: S Avramovici-Grisaru; S Sarel; Gabriela Link; Chaim Hershko
Syntheses of iron bis(pyridoxal isonicotinoylhydrazone)s and the in vivo iron-removal properties of some pyridoxal derivatives.
Journal of medicinal chemistry 1983;26(2):298-302.
1981: Chaim Hershko; S Avramovici-Grisaru; Gabriela Link; L Gelfand; S Sarel
Mechanism of in vivo iron chelation by pyridoxal isonicotinoyl hydrazone and other imino derivatives of pyridoxal.
The Journal of laboratory and clinical medicine 1981;98(1):99-108.