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Sara Linse

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TOP 3
Nikolai Slavov; Jannette Carey; Sara Linse
Calmodulin transduces ca(2+) oscillations into differential regulation of its target proteins.
Risto Cukalevski; Birgitta Frohm; Eva Thulin; Dominic Walsh; Barry Boland; Sara Linse
Role of aromatic side chains in amyloid β-protein aggregation.
Hanna Willander; Jenny Presto; Glareh Askarieh; Henrik Biverstål; Birgitta Frohm; Jan Johansson; Stefan D Knight; Sara Linse
BRICHOS domains efficiently delay fibrillation of amyloid β-peptide.

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All Publications

2013: Nikolai Slavov; Jannette Carey; Sara Linse
Calmodulin transduces ca(2+) oscillations into differential regulation of its target proteins.
ACS chemical neuroscience 2013;4(4):601-12.
2012: Risto Cukalevski; Birgitta Frohm; Eva Thulin; Dominic Walsh; Barry Boland; Sara Linse
Role of aromatic side chains in amyloid β-protein aggregation.
ACS chemical neuroscience 2012;3(12):1008-16.
2012: Hanna Willander; Jenny Presto; Glareh Askarieh; Henrik Biverstål; Birgitta Frohm; Jan Johansson; Stefan D Knight; Sara Linse
BRICHOS domains efficiently delay fibrillation of amyloid β-peptide.
The Journal of biological chemistry 2012;287(37):31608-17.
2012: Petra Behnen; Tommy Cedervall; Elizabeth Davis; Erin Delaney; Birgitta Frohm; David O'Connell; Karin S Akerfeldt; Mikael Bauer; Sara Linse
Calcium-dependent interaction of calmodulin with human 80S ribosomes and polyribosomes.
Biochemistry 2012;51(34):6718-27.
2012: Cecilia Oslakovic; Sara Linse; Tommy Cedervall; Björn Dahlbäck
Polystyrene nanoparticles affecting blood coagulation.
Nanomedicine : nanotechnology, biology, and medicine 2012;8(6):981-6.
2012: Sílvia A Ferreira; Birgitta Frohm; Francisco M Gama; Sara Linse; Cecilia Oslakovic; Risto Cukalevski; Björn Dahlbäck; Tommy Cedervall
Biocompatibility of mannan nanogel--safe interaction with plasma proteins.
Biochimica et biophysica acta 2012;1820(7):1043-51.
2012: Celia Cabaleiro-Lago; Olga Szczepankiewicz; Sara Linse
The effect of nanoparticles on amyloid aggregation depends on the protein stability and intrinsic aggregation rate.
Langmuir : the ACS journal of surfaces and colloids 2012;28(3):1852-7.
2012: Tommy Cedervall; Birgitta Frohm; Lars-Anders Hansson; Mercy Lard; Sara Linse
Food chain transport of nanoparticles affects behaviour and fat metabolism in fish.
PloS one 2012;7(2):e32254.
2011: Risto Cukalevski; Björn Dahlbäck; Sara Linse; Martin Lundqvist; Cecilia Oslakovic; Tommy Cedervall
Structural changes in apolipoproteins bound to nanoparticles.
Langmuir : the ACS journal of surfaces and colloids 2011;27(23):14360-9.
2011: Gabriel Svensson; Axel Hyrenius Wittsten; Sara Linse; Katrin Mani
The structural role of N-linked glycans on human glypican-1.
Biochemistry 2011;50(43):9377-87.
2011: Björn Linse; Sara Linse
Monte Carlo simulations of protein amyloid formation reveal origin of sigmoidal aggregation kinetics.
Molecular bioSystems 2011;7(7):2296-303.
2011: Mikael C Bauer; Dolores J Cahill; Magdalena Maj; David J O'Connell; Ludwig Wagner; Sara Linse
Identification of a high-affinity network of secretagogin-binding proteins involved in vesicle secretion.
Molecular bioSystems 2011;7(7):2196-204.
2011: Olga Szczepankiewicz; Celia Cabaleiro-Lago; Gian Gaetano Tartaglia; Michele Vendruscolo; Thérèse Hunter; Gary J Hunter; Hanna Nilsson; Eva Thulin; Sara Linse
Interactions in the native state of monellin, which play a protective role against aggregation.
Molecular bioSystems 2011;7(2):521-32.
2011: David J O'Connell; Sara Linse; Mikael Bauer; Dolores J Cahill
Probing calmodulin protein-protein interactions using high-content protein arrays.
Methods in molecular biology (Clifton, N.J.) 2011;785():289-303.
2011: Mikael Bauer; Dolores J Cahill; Sara Linse; Magdalena Maj; Ludwig Wagner; David J O'Connell
Protein networks involved in vesicle fusion, transport, and storage revealed by array-based proteomics.
Methods in molecular biology (Clifton, N.J.) 2011;781():47-58.
2011: Eva Thulin; Tõnu Kesvatera; Sara Linse
Molecular determinants of S100B oligomer formation.
PloS one 2011;6(3):e14768.
2010: Stina Lindman; Mikael C Bauer; Mikael Lund; Carl Diehl; Frans A A Mulder; Mikael Akke; Sara Linse
pK(a) values for the unfolded state under native conditions explain the pH-dependent stability of PGB1.
Biophysical journal 2010;99(10):3365-73.
2010: Stina Lindman; Armando Hernandez-Garcia; Olga Szczepankiewicz; Birgitta Frohm; Sara Linse
In vivo protein stabilization based on fragment complementation and a split GFP system.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(46):19826-31.
2010: David J O'Connell; Mikael C Bauer; John O'Brien; Winifred M Johnson; Catherine A Divizio; Sara L O'Kane; Tord Berggård; Alejandro Merino; Karin S Akerfeldt; Sara Linse; Dolores J Cahill
Integrated protein array screening and high throughput validation of 70 novel neural calmodulin-binding proteins.
Molecular & cellular proteomics : MCP 2010;9(6):1118-32.
2010: Erik Hellstrand; Emma Sparr; Sara Linse
Retardation of Abeta fibril formation by phospholipid vesicles depends on membrane phase behavior.
Biophysical journal 2010;98(10):2206-14.
2010: Celia Cabaleiro-Lago; Kenneth A Dawson; Iseult Lynch; Fiona Quinlan-Pluck; Sara Linse
Dual effect of amino modified polystyrene nanoparticles on amyloid β protein fibrillation.
ACS chemical neuroscience 2010;1(4):279-87.
2010: Celia Cabaleiro-Lago; Iseult Lynch; Kenneth A Dawson; Sara Linse
Inhibition of IAPP and IAPP(20-29) fibrillation by polymeric nanoparticles.
Langmuir : the ACS journal of surfaces and colloids 2010;26(5):3453-61.
2009: Gabriel Svensson; Sara Linse; Katrin Mani
Chemical and thermal unfolding of glypican-1: protective effect of heparan sulfate against heat-induced irreversible aggregation.
Biochemistry 2009;48(42):9994-10004.
2009: Stina Lindman; Ida Johansson; Eva Thulin; Sara Linse
Green fluorescence induced by EF-hand assembly in a split GFP system.
Protein science : a publication of the Protein Society 2009;18(6):1221-9.
2009: Erik Hellstrand; Iseult Lynch; Astra Andersson; Torbjörn Drakenberg; Björn Dahlbäck; Kenneth A Dawson; Sara Linse; Tommy Cedervall
Complete high-density lipoproteins in nanoparticle corona.
The FEBS journal 2009;276(12):3372-81.
2009: Mikael C Bauer; Wei-Feng Xue; Sara Linse
Protein GB1 folding and assembly from structural elements.
International journal of molecular sciences 2009;10(4):1552-66.
2009: Dominic M Walsh; Eva Thulin; Aedín M Minogue; Niklas Gustavsson; Eric Pang; David B Teplow; Sara Linse
A facile method for expression and purification of the Alzheimer's disease-associated amyloid beta-peptide.
The FEBS journal 2009;276(5):1266-81.
2009: Wei-Feng Xue; Olga Szczepankiewicz; Eva Thulin; Sara Linse; Jannette Carey
Role of protein surface charge in monellin sweetness.
Biochimica et biophysica acta 2009;1794(3):410-20.
2008: Celia Cabaleiro-Lago; Fiona Quinlan-Pluck; Iseult Lynch; Stina Lindman; Aedin M Minogue; Eva Thulin; Dominic M Walsh; Kenneth A Dawson; Sara Linse
Inhibition of amyloid beta protein fibrillation by polymeric nanoparticles.
Journal of the American Chemical Society 2008;130(46):15437-43.
2008: Ellen Wang; Mikael C Bauer; Annika Rogstam; Sara Linse; Derek Logan; Claes von Wachenfeldt
Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex.
Molecular microbiology 2008;69(2):466-78.
2008: Mikael C Bauer; David O'Connell; Dolores J Cahill; Sara Linse
Calmodulin binding to the polybasic C-termini of STIM proteins involved in store-operated calcium entry.
Biochemistry 2008;47(23):6089-91.
2008: Mikael C Bauer; Hanna Nilsson; Eva Thulin; Birgitta Frohm; Johan Malm; Sara Linse
Zn2+ binding to human calbindin D(28k) and the role of histidine residues.
Protein science : a publication of the Protein Society 2008;17(4):760-7.
2008: Aaron P Yamniuk; Jessica L Gifford; Sara Linse; Hans J Vogel
Effects of metal-binding loop mutations on ligand binding to calcium- and integrin-binding protein 1. Evolution of the EF-hand?
Biochemistry 2008;47(6):1696-707.
2007: Ingemar André; Sara Linse; Frans A A Mulder
Residue-specific pKa determination of lysine and arginine side chains by indirect 15N and 13C NMR spectroscopy: application to apo calmodulin.
Journal of the American Chemical Society 2007;129(51):15805-13.
2007: Jannette Carey; Stina Lindman; Mikael Bauer; Sara Linse
Protein reconstitution and three-dimensional domain swapping: benefits and constraints of covalency.
Protein science : a publication of the Protein Society 2007;16(11):2317-33.
2007: Iseult Lynch; Tommy Cedervall; Martin Lundqvist; Celia Cabaleiro-Lago; Sara Linse; Kenneth A Dawson
The nanoparticle-protein complex as a biological entity; a complex fluids and surface science challenge for the 21st century.
Advances in colloid and interface science 2007;134-135():167-74.
2007: Tord Berggård; Sara Linse; Peter James
Methods for the detection and analysis of protein-protein interactions.
Proteomics 2007;7(16):2833-42.
2007: Sara Linse; Celia Cabaleiro-Lago; Wei-Feng Xue; Iseult Lynch; Stina Lindman; Eva Thulin; Sheena E Radford; Kenneth A Dawson
Nucleation of protein fibrillation by nanoparticles.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(21):8691-6.
2007: Stina Lindman; Iseult Lynch; Eva Thulin; Hanna Nilsson; Kenneth A Dawson; Sara Linse
Systematic investigation of the thermodynamics of HSA adsorption to N-iso-propylacrylamide/N-tert-butylacrylamide copolymer nanoparticles. Effects of particle size and hydrophobicity.
Nano letters 2007;7(4):914-20.
2007: Tommy Cedervall; Iseult Lynch; Stina Lindman; Tord Berggård; Eva Thulin; Hanna Nilsson; Kenneth A Dawson; Sara Linse
Understanding the nanoparticle-protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(7):2050-5.
2007: Tommy Cedervall; Iseult Lynch; Martina Foy; Tord Berggård; Seamas C Donnelly; Gerard Cagney; Sara Linse; Kenneth A Dawson
Detailed identification of plasma proteins adsorbed on copolymer nanoparticles.
Angewandte Chemie (International ed. in English) 2007;46(30):5754-6.
2007: Stina Lindman; Sara Linse; Frans A A Mulder; Ingemar André
pK(a) values for side-chain carboxyl groups of a PGB1 variant explain salt and pH-dependent stability.
Biophysical journal 2007;92(1):257-66.
2007: Annika Rogstam; Sara Linse; Anders Lindqvist; Peter James; Ludwig Wagner; Tord Berggård
Binding of calcium ions and SNAP-25 to the hexa EF-hand protein secretagogin.
The Biochemical journal 2007;401(1):353-63.
2006: Stina Lindman; Sara Linse; Frans A A Mulder; Ingemar André
Electrostatic contributions to residue-specific protonation equilibria and proton binding capacitance for a small protein.
Biochemistry 2006;45(47):13993-4002.
2006: Kristina E M Persson; Johan Stenflo; Sara Linse; Yvonne Stenberg; Roger J S Preston; David A Lane; Suely M Rezende
Binding of calcium to anticoagulant protein S: role of the fourth EGF module.
Biochemistry 2006;45(35):10682-9.
2006: Wei-Feng Xue; Olga Szczepankiewicz; Mikael C Bauer; Eva Thulin; Sara Linse
Intra- versus intermolecular interactions in monellin: contribution of surface charges to protein assembly.
Journal of molecular biology 2006;358(5):1244-55.
2006: Cynthia F Shuman; Ronny Jiji; Karin S Kerfeldt; Sara Linse
Reconstitution of calmodulin from domains and subdomains: Influence of target peptide.
Journal of molecular biology 2006;358(3):870-81.
2006: Stina Lindman; Wei-Feng Xue; Olga Szczepankiewicz; Mikael C Bauer; Hanna Nilsson; Sara Linse
Salting the charged surface: pH and salt dependence of protein G B1 stability.
Biophysical journal 2006;90(8):2911-21.
2006: Ingemar André; Tõnu Kesvatera; Bo Jönsson; Sara Linse
Salt enhances calmodulin-target interaction.
Biophysical journal 2006;90(8):2903-10.
2006: Ingemar André; J Persson; A M Blom; H Nilsson; Torbjörn Drakenberg; Gunnar Lindahl; Sara Linse
Streptococcal M protein: structural studies of the hypervariable region, free and bound to human C4BP.
Biochemistry 2006;45(14):4559-68.
2006: Iseult Lynch; Kenneth A Dawson; Sara Linse
Detecting cryptic epitopes created by nanoparticles.
Science's STKE : signal transduction knowledge environment 2006;2006(327):pe14.
2006: Tord Berggård; Giorgio Arrigoni; Olof Olsson; Malin Fex; Sara Linse; Peter James
140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry.
Journal of proteome research 2006;5(3):669-87.
2005: Jonas Fast; Ann-Kristin Mossberg; Hanna Nilsson; Catharina Svanborg; Mikael Akke; Sara Linse
Compact oleic acid in HAMLET.
FEBS letters 2005;579(27):6095-100.
2005: Tommy Cedervall; Ingemar André; Cheryl Selah; James P Robblee; Peter C Krecioch; Robert Fairman; Sara Linse; Karin S Akerfeldt
Calbindin D28k EF-hand ligand binding and oligomerization: four high-affinity sites--three modes of action.
Biochemistry 2005;44(41):13522-32.
2005: Malgorzata Palczewska; Gyula Batta; Patrick Groves; Sara Linse; Jacek Kuznicki
Characterization of calretinin I-II as an EF-hand, Ca2+, H+-sensing domain.
Protein science : a publication of the Protein Society 2005;14(7):1879-87.
2005: Christophe Vanbelle; Frédéric Halgand; Tommy Cedervall; Eva Thulin; Karin S Akerfeldt; Olivier Laprévote; Sara Linse
Deamidation and disulfide bridge formation in human calbindin D28k with effects on calcium binding.
Protein science : a publication of the Protein Society 2005;14(4):968-79.
2005: Daniele Dell'Orco; Wei-Feng Xue; Eva Thulin; Sara Linse
Electrostatic contributions to the kinetics and thermodynamics of protein assembly.
Biophysical journal 2005;88(3):1991-2002.
2005: Jonas Fast; Ann-Kristin Mossberg; Catharina Svanborg; Sara Linse
Stability of HAMLET--a kinetically trapped alpha-lactalbumin oleic acid complex.
Protein science : a publication of the Protein Society 2005;14(2):329-40.
2005: Tommy Cedervall; Tord Berggård; Valerie Borek; Eva Thulin; Sara Linse; Karin S Akerfeldt
Redox sensitive cysteine residues in calbindin D28k are structurally and functionally important.
Biochemistry 2005;44(2):684-93.
2004: Wei-Feng Xue; Jannette Carey; Sara Linse
Multi-method global analysis of thermodynamics and kinetics in reconstitution of monellin.
Proteins 2004;57(3):586-95.
2004: Ingemar André; Tõnu Kesvatera; Bo Jönsson; Karin S Akerfeldt; Sara Linse
The role of electrostatic interactions in calmodulin-peptide complex formation.
Biophysical journal 2004;87(3):1929-38.
2004: Magnus Helgstrand; Christophe Vanbelle; Eva Thulin; Sara Linse; Mikael Akke
Sequential 1H, 15N and 13C NMR assignment of human calbindin D28k.
Journal of biomolecular NMR 2004;28(3):305-6.
2003: Malin Svensson; Ann-Kristin Mossberg; Jenny Pettersson; Sara Linse; Catharina Svanborg
Lipids as cofactors in protein folding: stereo-specific lipid-protein interactions are required to form HAMLET (human alpha-lactalbumin made lethal to tumor cells).
Protein science : a publication of the Protein Society 2003;12(12):2805-14.
2003: Malin Svensson; Jonas Fast; Ann-Kristin Mossberg; Caroline Düringer; Lotta Gustafsson; Oskar Hallgren; Charles L Brooks; Lawrence Berliner; Sara Linse; Catharina Svanborg
Alpha-lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human alpha-lactalbumin made lethal to tumor cells).
Protein science : a publication of the Protein Society 2003;12(12):2794-804.
2003: Catharina Svanborg; Helena Agerstam; Annika Aronson; Rolf Bjerkvig; Caroline Düringer; Walter Fischer; Lotta Gustafsson; Oskar Hallgren; Irene Leijonhuvud; Sara Linse; Ann-Kristin Mossberg; Hanna Nilsson; Jenny Pettersson; Malin Svensson
HAMLET kills tumor cells by an apoptosis-like mechanism--cellular, molecular, and therapeutic aspects.
Advances in cancer research 2003;88():1-29.
2002: Maria Håkansson; Sara Linse
Protein reconstitution and 3D domain swapping.
Current protein & peptide science 2002;3(6):629-42.
2002: Thomas Areschoug; Sara Linse; Margaretha Stålhammar-Carlemalm; Lars-Olof Hedén; Gunnar Lindahl
A proline-rich region with a highly periodic sequence in Streptococcal beta protein adopts the polyproline II structure and is exposed on the bacterial surface.
Journal of bacteriology 2002;184(22):6376-83.
2002: Tord Berggard; Olga Szczepankiewicz; Eva Thulin; Sara Linse
Myo-inositol monophosphatase is an activated target of calbindin D28k.
The Journal of biological chemistry 2002;277(44):41954-9.
2002: Charlotta Sandin; Sara Linse; Thomas Areschoug; Jenny M Woof; Jesper Reinholdt; Gunnar Lindahl
Isolation and detection of human IgA using a streptococcal IgA-binding peptide.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(3):1357-64.
2002: Ingemar André; Sara Linse
Measurement of Ca2+-binding constants of proteins and presentation of the CaLigator software.
Analytical biochemistry 2002;305(2):195-205.
2002: Karin Julenius; James P Robblee; Eva Thulin; Bryan E Finn; Robert Fairman; Sara Linse
Coupling of ligand binding and dimerization of helix-loop-helix peptides: spectroscopic and sedimentation analyses of calbindin D9k EF-hands.
Proteins 2002;47(3):323-33.
2002: Tord Berggård; Simona Miron; Patrik Onnerfjord; Eva Thulin; Karin S Akerfeldt; Jan J Enghild; Mikael Akke; Sara Linse
Calbindin D28k exhibits properties characteristic of a Ca2+ sensor.
The Journal of biological chemistry 2002;277(19):16662-72.
2002: Tusar Kanti Giri; Sara Linse; Pablo García de Frutos; Tomio Yamazaki; Bruno Villoutreix; Björn Dahlbäck
Structural requirements of anticoagulant protein S for its binding to the complement regulator C4b-binding protein.
The Journal of biological chemistry 2002;277(17):15099-106.
2002: Malin Svensson; Caroline Düringer; Oskar Hallgren; Ann-Kristin Mossberg; Anders Håkansson; Sara Linse; Catharina Svanborg
Hamlet--a complex from human milk that induces apoptosis in tumor cells but spares healthy cells.
Advances in experimental medicine and biology 2002;503():125-32.
2002: Sara Linse
Calcium binding to proteins studied via competition with chromophoric chelators.
Methods in molecular biology (Clifton, N.J.) 2002;173():15-24.
2001: Tõnu Kesvatera; B Jönsson; A Telling; Vello Tõugu; H Vija; Eva Thulin; Sara Linse
Calbindin D(9k): a protein optimized for calcium binding at neutral pH.
Biochemistry 2001;40(50):15334-40.
2001: Tõnu Kesvatera; B Jönsson; Eva Thulin; Sara Linse
Focusing of the electrostatic potential at EF-hands of calbindin D(9k): titration of acidic residues.
Proteins 2001;45(2):129-35.
2001: E Morfeldt; Karin Berggård; J Persson; Torbjörn Drakenberg; Eskil Johnsson; E Lindahl; Sara Linse; Gunnar Lindahl
Isolated hypervariable regions derived from streptococcal M proteins specifically bind human C4b-binding protein: implications for antigenic variation.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(7):3870-7.
2001: Jonas Fast; Maria Håkansson; Andreas Muranyi; GP Gippert; Eva Thulin; Johan Evenäs; LA Svensson; Sara Linse
Symmetrical stabilization of bound Ca2+ ions in a cooperative pair of EF-hands through hydrogen bonding of coordinating water molecules in calbindin D(9k).
Biochemistry 2001;40(33):9887-95.
2001: Maria Håkansson; A Svensson; Jonas Fast; Sara Linse
An extended hydrophobic core induces EF-hand swapping.
Protein science : a publication of the Protein Society 2001;10(5):927-33.
2001: Tord Berggård; Karin Julenius; A Ogard; Torbjörn Drakenberg; Sara Linse
Fragment complementation studies of protein stabilization by hydrophobic core residues.
Biochemistry 2001;40(5):1257-64.
2000: Tord Berggård; Eva Thulin; Karin S Akerfeldt; Sara Linse
Fragment complementation of calbindin D28k.
Protein science : a publication of the Protein Society 2000;9(11):2094-108.
2000: Tord Berggård; M Silow; Eva Thulin; Sara Linse
Ca(2+)- and H(+)-dependent conformational changes of calbindin D(28k).
Biochemistry 2000;39(23):6864-73.
2000: Malin Svensson; Anders Håkansson; Ann-Kristin Mossberg; Sara Linse; Catharina Svanborg
Conversion of alpha-lactalbumin to a protein inducing apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(8):4221-6.
2000: Sara Linse; M Voorhies; E Norström; D A Schultz
An EF-hand phage display study of calmodulin subdomain pairing.
Journal of molecular biology 2000;296(2):473-86.
2000: Anders Håkansson; Malin Svensson; Ann-Kristin Mossberg; H Sabharwal; Sara Linse; I Lazou; Bo Lonnerdal; Catharina Svanborg
A folding variant of alpha-lactalbumin with bactericidal activity against Streptococcus pneumoniae.
Molecular microbiology 2000;35(3):589-600.
1999: P Evenäs; Pablo García de Frutos; Sara Linse; Björn Dahlbäck
Both G-type domains of protein S are required for the high-affinity interaction with C4b-binding protein.
European journal of biochemistry / FEBS 1999;266(3):935-42.
1999: Tõnu Kesvatera; B Jönsson; Eva Thulin; Sara Linse
Ionization behavior of acidic residues in calbindin D(9k).
Proteins 1999;37(1):106-15.
1999: A Malmendal; Sara Linse; Johan Evenäs; Sture Forsén; Torbjörn Drakenberg
Battle for the EF-hands: magnesium-calcium interference in calmodulin.
Biochemistry 1999;38(36):11844-50.
1999: T Osterlund; D J Beussman; Karin Julenius; P H Poon; Sara Linse; J Shabanowitz; D F Hunt; M C Schotz; Zygmunt S Derewenda; Cecilia Holm
Domain identification of hormone-sensitive lipase by circular dichroism and fluorescence spectroscopy, limited proteolysis, and mass spectrometry.
The Journal of biological chemistry 1999;274(22):15382-8.
1999: Eva Thulin; Sara Linse
Expression and purification of human calbindin D28k.
Protein expression and purification 1999;15(3):265-70.
1999: Malin Svensson; H Sabharwal; Anders Håkansson; Ann-Kristin Mossberg; P Lipniunas; Hakon Leffler; Catharina Svanborg; Sara Linse
Molecular characterization of alpha-lactalbumin folding variants that induce apoptosis in tumor cells.
The Journal of biological chemistry 1999;274(10):6388-96.
1998: Birthe Kragelund; M Jönsson; G Bifulco; W J Chazin; H Nilsson; Bryan E Finn; Sara Linse
Hydrophobic core substitutions in calbindin D9k: effects on Ca2+ binding and dissociation.
Biochemistry 1998;37(25):8926-37.
1998: Karin Julenius; Eva Thulin; Sara Linse; Bryan E Finn
Hydrophobic core substitutions in calbindin D9k: effects on stability and structure.
Biochemistry 1998;37(25):8915-25.
1997: Bruno Villoutreix; Pablo García de Frutos; Magnus Lövenklev; Sara Linse; Per Fernlund; Björn Dahlbäck
SHBG region of the anticoagulant cofactor protein S: secondary structure prediction, circular dichroism spectroscopy, and analysis of naturally occurring mutations.
Proteins 1997;29(4):478-91.
1997: Sara Linse; Eva Thulin; L K Gifford; D Radzewsky; J Hagan; R R Wilk; Karin S Akerfeldt
Domain organization of calbindin D28k as determined from the association of six synthetic EF-hand fragments.
Protein science : a publication of the Protein Society 1997;6(11):2385-96.
1997: Yvonne Stenberg; Sara Linse; Torbjörn Drakenberg; Johan Stenflo
The high affinity calcium-binding sites in the epidermal growth factor module region of vitamin K-dependent protein S.
The Journal of biological chemistry 1997;272(37):23255-60.
1997: Sara Linse; Y Härdig; D A Schultz; B Dahlbäck
A region of vitamin K-dependent protein S that binds to C4b binding protein (C4BP) identified using bacteriophage peptide display libraries.
The Journal of biological chemistry 1997;272(23):14658-65.
1997: M Andersson; A Malmendal; Sara Linse; I Ivarsson; Sture Forsén; LA Svensson
Structural basis for the negative allostery between Ca(2+)- and Mg(2+)-binding in the intracellular Ca(2+)-receptor calbindin D9k.
Protein science : a publication of the Protein Society 1997;6(6):1139-47.
1997: X He; L Shen; A C Malmborg; Kenneth J Smith; B Dahlback; Sara Linse
Binding site for C4b-binding protein in vitamin K-dependent protein S fully contained in carboxy-terminal laminin-G-type repeats. A study using recombinant factor IX-protein S chimeras and surface plasmon resonance.
Biochemistry 1997;36(12):3745-54.
1997: Patrick Groves; Sara Linse; Eva Thulin; Sture Forsén
A calbindin D9k mutant containing a novel structural extension: 1H nuclear magnetic resonance studies.
Protein science : a publication of the Protein Society 1997;6(2):323-30.
1996: Tõnu Kesvatera; B Jönsson; Eva Thulin; Sara Linse
Measurement and modelling of sequence-specific pKa values of lysine residues in calbindin D9k.
Journal of molecular biology 1996;259(4):828-39.
1996: K S Akerfeldt; A N Coyne; R R Wilk; Eva Thulin; Sara Linse
Ca2+-binding stoichiometry of calbindin D28k as assessed by spectroscopic analyses of synthetic peptide fragments.
Biochemistry 1996;35(12):3662-9.
1995: Sture Forsén; Sara Linse
Cooperativity: over the Hill.
Trends in biochemical sciences 1995;20(12):495-7.
1995: Sara Linse; W J Chazin
Quantitative measurements of the cooperativity in an EF-hand protein with sequential calcium binding.
Protein science : a publication of the Protein Society 1995;4(6):1038-44.
1995: Sara Linse; B Jönsson; W J Chazin
The effect of protein concentration on ion binding.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):4748-52.
1995: Sara Linse; S Forsén
Determinants that govern high-affinity calcium binding.
Advances in second messenger and phosphoprotein research 1995;30():89-151.
1994: Tõnu Kesvatera; B Jönsson; Eva Thulin; Sara Linse
Binding of Ca2+ to calbindin D9k: structural stability and function at high salt concentration.
Biochemistry 1994;33(47):14170-6.
1994: Sara Linse; N R Bylsma; Torbjörn Drakenberg; P Sellers; Sture Forsén; Eva Thulin; L A Svensson; I Zajtzeva; V Zajtsev; J Marek
A calbindin D9k mutant with reduced calcium affinity and enhanced cooperativity. Metal ion binding, stability, and structural studies.
Biochemistry 1994;33(41):12478-86.
1993: Y Waltersson; Sara Linse; P Brodin; Thomas Grundström
Mutational effects on the cooperativity of Ca2+ binding in calmodulin.
Biochemistry 1993;32(31):7866-71.
1993: Sara Linse; Eva Thulin; P Sellers
Disulfide bonds in homo- and heterodimers of EF-hand subdomains of calbindin D9k: stability, calcium binding, and NMR studies.
Protein science : a publication of the Protein Society 1993;2(6):985-1000.
1993: S Forsén; C Johansson; Sara Linse
Calcium nuclear magnetic resonance.
Methods in enzymology 1993;227():107-18.
1991: B Svensson; B Jönsson; C E Woodward; Sara Linse
Ion-binding properties of calbindin D9k: a Monte Carlo simulation study.
Biochemistry 1991;30(21):5209-17.
1991: Sara Linse; A Helmersson; Sture Forsén
Calcium binding to calmodulin and its globular domains.
The Journal of biological chemistry 1991;266(13):8050-4.
1991: Sara Linse; C Johansson; P Brodin; Thomas Grundström; Torbjörn Drakenberg; Sture Forsén
Electrostatic contributions to the binding of Ca2+ in calbindin D9k.
Biochemistry 1991;30(1):154-62.
1991: Johan Stenflo; Acke Ohlin; E Persson; C Valcarce; Jan Astermark; Torbjörn Drakenberg; M Selander; Sara Linse; I Björk
Epidermal growth factor-like domains in the vitamin K-dependent clotting factors. Some structure-function relationships.
Annals of the New York Academy of Sciences 1991;614():11-29.
1991: Sture Forsén; Sara Linse; Torbjörn Drakenberg; J Kördel; Mikael Akke; P Sellers; C Johansson; Eva Thulin; I Andersson; P Brodin
Ca2+ binding in proteins of the calmodulin superfamily: cooperativity, electrostatic contributions and molecular mechanisms.
Ciba Foundation symposium 1991;161():222-36.
1990: Björn Dahlbäck; B Hildebrand; Sara Linse
Novel type of very high affinity calcium-binding sites in beta-hydroxyasparagine-containing epidermal growth factor-like domains in vitamin K-dependent protein S.
The Journal of biological chemistry 1990;265(30):18481-9.
1990: Sara Linse; O Teleman; Torbjörn Drakenberg
Ca2+ binding to calbindin D9k strongly affects backbone dynamics: measurements of exchange rates of individual amide protons using 1H NMR.
Biochemistry 1990;29(25):5925-34.
1990: Stephen Martin; Sara Linse; C Johansson; Peter M Bayley; S Forsén
Protein surface charges and Ca2+ binding to individual sites in calbindin D9k: stopped-flow studies.
Biochemistry 1990;29(17):4188-93.
1990: Sture Forsén; Torbjörn Drakenberg; C Johansson; Sara Linse; Eva Thulin; J Kördel
Protein engineering and structure/function relations in bovine calbindin D9k.
Advances in experimental medicine and biology 1990;269():37-42.
1989: E Persson; M Selander; Sara Linse; Torbjörn Drakenberg; Acke Ohlin; Johan Stenflo
Calcium binding to the isolated beta-hydroxyaspartic acid-containing epidermal growth factor-like domain of bovine factor X.
The Journal of biological chemistry 1989;264(28):16897-904.
1989: Sture Forsén; Mikael Akke; P Brodin; P Bayley; Torbjörn Drakenberg; Thomas Grundström; C Johansson; Sara Linse; S Martin; Eva Thulin
Neutralization of surface charges markedly affects the properties of bovine calbindin D9k.
Advances in experimental medicine and biology 1989;255():185-94.
1988: Sture Forsén; Sara Linse; Eva Thulin; B Lindegård; S R Martin; P M Bayley; P Brodin; Thomas Grundström
Kinetics of calcium binding to calbindin mutants.
European journal of biochemistry / FEBS 1988;177(1):47-52.
1988: Sara Linse; P Brodin; C Johansson; Eva Thulin; Thomas Grundström; Sture Forsén
The role of protein surface charges in ion binding.
Nature 1988;335(6191):651-2.
1988: B Wendt; T Hofmann; S R Martin; P Bayley; P Brodin; Thomas Grundström; Eva Thulin; Sara Linse; Sture Forsén
Effect of amino acid substitutions and deletions on the thermal stability, the pH stability and unfolding by urea of bovine calbindin D9k.
European journal of biochemistry / FEBS 1988;175(3):439-45.
1988: Acke Ohlin; Sara Linse; Johan Stenflo
Calcium binding to the epidermal growth factor homology region of bovine protein C.
The Journal of biological chemistry 1988;263(15):7411-7.
1987: Sara Linse; P Brodin; Torbjörn Drakenberg; Eva Thulin; P Sellers; K Elmdén; Thomas Grundström; Sture Forsén
Structure-function relationships in EF-hand Ca2+-binding proteins. Protein engineering and biophysical studies of calbindin D9k.
Biochemistry 1987;26(21):6723-35.
1986: S R Martin; Sara Linse; P M Bayley; S Forsén
Kinetics of cadmium and terbium dissociation from calmodulin and its tryptic fragments.
European journal of biochemistry / FEBS 1986;161(3):595-601.