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Eleanor Barnes

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Cristina Bucci; Annabel Christian; Jane Collier; Vicki M Flemming; John Halliday; Abby Harrison; William Irving; Paul Klenerman; Chris Manganis; Annette von Delft; Eleanor Barnes
'Favourable' IL28B polymorphisms are associated with a marked increase in baseline viral load in hepatitis C virus subtype 3a infection and do not predict a sustained virological response after 24 weeks of therapy.
Emma L Culver; David Delaney; Antony J Ellis; Bruce George; Eleanor Barnes; Roger W Chapman
A rare cause of an ileocaecal mass and lymphadenopathy.
Lucy J Walker; David H Adams; Eleanor Barnes; Vicki Fleming; Alessandra Geremia; Willem A Hanekom; Yu-Hoi Kang; Olivier Lantz; Georg M Lauer; Alistair Leslie; Ye Oo; Fiona Powrie; Narayan Ramamurthy; Natasha Sahgal; Thomas J Scriba; Matthew O Smith; Hannah Tharmalingham; Paul Klenerman
Human MAIT and CD8αα cells develop from a pool of type-17 precommitted CD8+ T cells.

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All Publications

2013: Cristina Bucci; Annabel Christian; Jane Collier; Vicki M Flemming; John Halliday; Abby Harrison; William Irving; Paul Klenerman; Chris Manganis; Annette von Delft; Eleanor Barnes
'Favourable' IL28B polymorphisms are associated with a marked increase in baseline viral load in hepatitis C virus subtype 3a infection and do not predict a sustained virological response after 24 weeks of therapy.
The Journal of general virology 2013;94(Pt 6):1259-65.
2012: Emma L Culver; David Delaney; Antony J Ellis; Bruce George; Eleanor Barnes; Roger W Chapman
A rare cause of an ileocaecal mass and lymphadenopathy.
Gut 2012;61(6):819-20, 917.
2012: Lucy J Walker; David H Adams; Eleanor Barnes; Vicki Fleming; Alessandra Geremia; Willem A Hanekom; Yu-Hoi Kang; Olivier Lantz; Georg M Lauer; Alistair Leslie; Ye Oo; Fiona Powrie; Narayan Ramamurthy; Natasha Sahgal; Thomas J Scriba; Matthew O Smith; Hannah Tharmalingham; Paul Klenerman
Human MAIT and CD8αα cells develop from a pool of type-17 precommitted CD8+ T cells.
Blood 2012;119(2):422-33.
2012: Bevin Gangadharan; Bettina Kampa; Paul Klenerman; Jan Rossa; Robin Antrobus; Manisha Bapat; Eleanor Barnes; David Chittenden; Raymond A Dwek; Nicole Zitzmann
Discovery of novel biomarker candidates for liver fibrosis in hepatitis C patients: a preliminary study.
PloS one 2012;7(6):e39603.
2011: Christabel Kelly; Paul Klenerman; Eleanor Barnes
Interferon lambdas: the next cytokine storm.
Gut 2011;60(9):1284-93.
2011: Bevin Gangadharan; Robin Antrobus; David Chittenden; Jan Rossa; Manisha Bapat; Paul Klenerman; Eleanor Barnes; Raymond A Dwek; Nicole Zitzmann
New approaches for biomarker discovery: the search for liver fibrosis markers in hepatitis C patients.
Journal of proteome research 2011;10(5):2643-50.
2011: John Halliday; Paul Klenerman; Eleanor Barnes
Vaccination for hepatitis C virus: closing in on an evasive target.
Expert review of vaccines 2011;10(5):659-72.
2011: Eleanor Barnes; Andrew J Pollard
Vaccines in clinical trials: infectious disease.
Expert review of vaccines 2011;10(5):555-7.
2010: Eleanor Barnes; Peter Flanagan; Anthony Brown; Nicola Robinson; Helen Brown; Myra McClure; Annette Oxenius; Jane Collier; Jonathan Weber; Huldrych Günthard; Bernard Hirschel; Sarah Fidler; Rodney Phillips; John Frater
Failure to detect xenotropic murine leukemia virus-related virus in blood of individuals at high risk of blood-borne viral infections.
The Journal of infectious diseases 2010;202(10):1482-5.
2010: Bounkong Syhavong; Bouachanh Rasachack; Lee D Smythe; Jean-Marc ROLAIN; Anne-Marie Roque-Afonso; Kemajittra Jenjaroen; Vimone Soukkhaserm; Simmaly Phongmany; Rattanaxay Phetsouvanh; Sune Soukkhaserm; Te Thammavong; Mayfong Mayxay; stuart blacksell; Eleanor Barnes; Philippe Parola; Elisabeth Dussaix; Didier Raoult; Isla Humphreys; Paul Klenerman; Nicholas J White; Paul N Newton
The infective causes of hepatitis and jaundice amongst hospitalised patients in Vientiane, Laos.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2010;104(7):475-83.
2010: Vicki Fleming; Gillian Harcourt; Eleanor Barnes; Paul Klenerman
Virological footprint of CD4+ T-cell responses during chronic hepatitis C virus infection.
The Journal of general virology 2010;91(Pt 6):1396-406.
2009: Isla Humphreys; Vicki Fleming; Paolo Fabris; Joe Parker; Bodo Schulenberg; Anthony Brown; Charis Demetriou; Silvana Gaudieri; Katja Pfafferott; Michaela Lucas; Jane Collier; Kuan-Hsiang Gary Huang; Oliver G Pybus; Paul Klenerman; Eleanor Barnes
Full-length characterization of hepatitis C virus subtype 3a reveals novel hypervariable regions under positive selection during acute infection.
Journal of virology 2009;83(22):11456-66.
2009: Eleanor Barnes; Huub Gelderblom; Isla Humphreys; Nasser Semmo; Henk W Reesink; Marcel G H M Beld; René A W van Lier; Paul Klenerman
Cellular immune responses during high-dose interferon-alpha induction therapy for hepatitis C virus infection.
The Journal of infectious diseases 2009;199(6):819-28.
2009: Oliver G Pybus; Eleanor Barnes; Rachel Taggart; Philippe Lemey; Peter V Markov; Bouachan Rasachak; Bounkong Syhavong; Rattanaphone Phetsouvanah; Isabelle Sheridan; Isla S Humphreys; Ling Lu; Paul N Newton; Paul Klenerman
Genetic history of hepatitis C virus in East Asia.
Journal of virology 2009;83(2):1071-82.
2008: Eleanor Barnes; M Salio; Vincenzo Cerundolo; L Francesco; Drew M Pardoll; Paul Klenerman; Andrea L Cox
Monocyte derived dendritic cells retain their functional capacity in patients following infection with hepatitis C virus.
Journal of viral hepatitis 2008;15(3):219-28.
2005: Mark Danta; Eleanor Barnes; Geoffrey Dusheiko
The surveillance and diagnosis of hepatocellular carcinoma.
European journal of gastroenterology & hepatology 2005;17(5):491-6.
2005: Nasser Semmo; Eleanor Barnes; Craig Taylor; John Kurtz; Gillian Harcourt; Neil Smith; Paul Klenerman
T-cell responses and previous exposure to hepatitis C virus in indeterminate blood donors.
Lancet 2005;365(9456):327-9.
2004: Georg M Lauer; Eleanor Barnes; Michaela Lucas; Joerg Timm; Kei Ouchi; Arthur Y Kim; Cheryl L Day; Gregory Robbins; Deborah R Casson; Markus Reiser; Geoffrey Dusheiko; Todd M Allen; Raymond T Chung; Bruce D Walker; Paul Klenerman
High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection.
Gastroenterology 2004;127(3):924-36.
2004: Eleanor Barnes; Mariolina Salio; Vincenzo Cerundolo; Joanne Medlin; Shona Murphy; Geoffrey Dusheiko; Paul Klenerman
Impact of alpha interferon and ribavirin on the function of maturing dendritic cells.
Antimicrobial agents and chemotherapy 2004;48(9):3382-9.
2004: Gillian Harcourt; Michaela Lucas; I Sheridan; Eleanor Barnes; Rodney Phillips; Paul Klenerman
Longitudinal mapping of protective CD4+ T cell responses against HCV: analysis of fluctuating dominant and subdominant HLA-DR11 restricted epitopes.
Journal of viral hepatitis 2004;11(4):324-31.
2004: Eleanor Barnes; Scott M Ward; Victoria O Kasprowicz; Geoffrey Dusheiko; Paul Klenerman; Michaela Lucas
Ultra-sensitive class I tetramer analysis reveals previously undetectable populations of antiviral CD8+ T cells.
European journal of immunology 2004;34(6):1570-7.
2004: Andreas Zafiropoulos; Eleanor Barnes; Clive Piggott; Paul Klenerman
Analysis of 'driver' and 'passenger' CD8+ T-cell responses against variable viruses.
Proceedings. Biological sciences / The Royal Society 2004;271 Suppl 3():S53-6.
2004: Michaela Lucas; Ana L Vargas Cuero; Georg M Lauer; Eleanor Barnes; Christian B Willberg; Nasser Semmo; Bruce D Walker; Rodney Phillips; Paul Klenerman
Pervasive influence of hepatitis C virus on the phenotype of antiviral CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(3):1744-53.
2003: Maria Kantzanou; Michaela Lucas; Eleanor Barnes; Harvki Komatsu; Geoffrey Dusheiko; Scott Ward; Gillian Harcourt; Paul Klenerman
Viral escape and T cell exhaustion in hepatitis C virus infection analysed using Class I peptide tetramers.
Immunology letters 2003;85(2):165-71.
2002: Eleanor Barnes; Gillian Harcourt; Dave Brown; Michaela Lucas; Rodney Phillips; Geoffrey Dusheiko; Paul Klenerman
The dynamics of T-lymphocyte responses during combination therapy for chronic hepatitis C virus infection.
Hepatology (Baltimore, Md.) 2002;36(3):743-54.
2002: Eleanor Barnes; Georg M Lauer; Bruce Walker; Paul Klenerman
T cell failure in hepatitis C virus infection.
Viral immunology 2002;15(2):285-93.
2002: Paul Klenerman; Michaela Lucas; Eleanor Barnes; Gillian Harcourt
Immunity to hepatitis C virus: stunned but not defeated.
Microbes and infection / Institut Pasteur 2002;4(1):57-65.
2000: Franziska Lechner; J Sullivan; Hans M L Spiegel; D F Nixon; B Ferrari; A Davis; B Borkowsky; H Pollack; Eleanor Barnes; Geoffrey Dusheiko; Paul Klenerman
Why do cytotoxic T lymphocytes fail to eliminate hepatitis C virus? Lessons from studies using major histocompatibility complex class I peptide tetramers.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2000;355(1400):1085-92.
2000: Geoffrey Dusheiko; Eleanor Barnes; G Webster; Simon Whalley
The science, economics, and effectiveness of combination therapy for hepatitis C.
Gut 2000;47(2):159-61.
2000: G Webster; Eleanor Barnes; D Brown; Geoffrey Dusheiko
HCV genotypes--role in pathogenesis of disease and response to therapy.
Baillière's best practice & research. Clinical gastroenterology 2000;14(2):229-40.
1999: Eleanor Barnes; G Webster; Simon Whalley; Geoffrey Dusheiko
Predictors of a favorable response to alpha interferon therapy for hepatitis C.
Clinics in liver disease 1999;3(4):775-91.
1999: Eleanor Barnes; G Webster; R Jacobs; Geoffrey Dusheiko
Long-term efficacy of treatment of chronic hepatitis C with alpha interferon or alpha interferon and ribavirin.
Journal of hepatology 1999;31 Suppl 1():244-9.