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Steven Linton

Research Profile

Chemicals & Drugs

Concepts & Ideas

Phenomena

Acylation

Disorders

Physiology

Cell Death

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Publications

TOP 3
Brett R Ullman; Teresa Aja; Ning Chen; Jose-Luis Diaz; Xin Gu; Julia Herrmann; Vincent J Kalish; Donald S Karanewsky; Lalitha Kodandapani; Joseph J Krebs; Steven D Linton; Steven P Meduna; Kip Nalley; Edward D Robinson; Silvio P Roggo; Robert O Sayers; Albert Schmitz; Robert J Ternansky; Kevin J Tomaselli; Joe C Wu
Structure-activity relationships within a series of caspase inhibitors. Part 2: Heterocyclic warheads.
Steven D Linton; Teresa Aja; Peter R Allegrini; Thomas L Deckwerth; Jose-Luis Diaz; Bastian Hengerer; Julia Herrmann; Kathy G Jahangiri; Joerg Kallen; Donald S Karanewsky; Steven P Meduna; Kip Nalley; Edward D Robinson; Silvio P Roggo; Giorgio Rovelli; Andre Sauter; Robert O Sayers; Albert Schmitz; Robert Smidt; Robert J Ternansky; Kevin J Tomaselli; Brett R Ullman; Christoph Wiessner; Joe C Wu
Oxamyl dipeptide caspase inhibitors developed for the treatment of stroke.
Steven D Linton; Donald S Karanewsky; Robert J Ternansky; Ning Chen; Xian Guo; Kathy G Jahangiri; Vincent J Kalish; Steven P Meduna; Edward D Robinson; Brett R Ullman; Joe C Wu; Brian Pham; Lalitha Kodandapani; Robert Smidt; Jose-Luis Diaz; Lawrence C Fritz; U von Krosigk; Silvio P Roggo; Albert Schmitz; Kevin J Tomaselli
Acyl dipeptides as reversible caspase inhibitors. Part 2: further optimization.

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All Publications

2005: Brett R Ullman; Teresa Aja; Ning Chen; Jose-Luis Diaz; Xin Gu; Julia Herrmann; Vincent J Kalish; Donald S Karanewsky; Lalitha Kodandapani; Joseph J Krebs; Steven D Linton; Steven P Meduna; Kip Nalley; Edward D Robinson; Silvio P Roggo; Robert O Sayers; Albert Schmitz; Robert J Ternansky; Kevin J Tomaselli; Joe C Wu
Structure-activity relationships within a series of caspase inhibitors. Part 2: Heterocyclic warheads.
Bioorganic & medicinal chemistry letters 2005;15(15):3632-6.
2004: Steven D Linton; Teresa Aja; Peter R Allegrini; Thomas L Deckwerth; Jose-Luis Diaz; Bastian Hengerer; Julia Herrmann; Kathy G Jahangiri; Joerg Kallen; Donald S Karanewsky; Steven P Meduna; Kip Nalley; Edward D Robinson; Silvio P Roggo; Giorgio Rovelli; Andre Sauter; Robert O Sayers; Albert Schmitz; Robert Smidt; Robert J Ternansky; Kevin J Tomaselli; Brett R Ullman; Christoph Wiessner; Joe C Wu
Oxamyl dipeptide caspase inhibitors developed for the treatment of stroke.
Bioorganic & medicinal chemistry letters 2004;14(10):2685-91.
2002: Steven D Linton; Donald S Karanewsky; Robert J Ternansky; Ning Chen; Xian Guo; Kathy G Jahangiri; Vincent J Kalish; Steven P Meduna; Edward D Robinson; Brett R Ullman; Joe C Wu; Brian Pham; Lalitha Kodandapani; Robert Smidt; Jose-Luis Diaz; Lawrence C Fritz; U von Krosigk; Silvio P Roggo; Albert Schmitz; Kevin J Tomaselli
Acyl dipeptides as reversible caspase inhibitors. Part 2: further optimization.
Bioorganic & medicinal chemistry letters 2002;12(20):2973-5.
2002: Steven D Linton; Donald S Karanewsky; Robert J Ternansky; Joe C Wu; Brian Pham; Lalitha Kodandapani; Robert Smidt; Jose-Luis Diaz; Lawrence C Fritz; Kevin J Tomaselli
Acyl dipeptides as reversible caspase inhibitors. Part 1: initial lead optimization.
Bioorganic & medicinal chemistry letters 2002;12(20):2969-71.
1998: Donald S Karanewsky; X Bai; Steven D Linton; JF Krebs; J Wu; Brian Pham; Kevin J Tomaselli
Conformationally constrained inhibitors of caspase-1 (interleukin-1 beta converting enzyme) and of the human CED-3 homologue caspase-3 (CPP32, apopain).
Bioorganic & medicinal chemistry letters 1998;8(19):2757-62.