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Andrzej Lipkowski

Research Profile

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Chemicals & Drugs

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Amino Acid Sequences

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Sergiusz Markowicz; Aleksandra Misicka; Zbigniew I Nowecki; Hanna Polowniak-Pracka; Piotr Rutkowski; Henryk Skurzak; Tomasz Switaj; Marzena Biernacka; Anna Jakubowska-Mucka; Andrzej W Lipkowski; Jan Walewski
Adjuvant vaccination with melanoma antigen-pulsed dendritic cells in stage III melanoma patients.
Jayapal Reddy Mallareddy; Judit Molnár; Péter Nagyőszi; Géza Tóth; Csilla Fazakas; István A Krizbai; Andrzej W Lipkowski; Imola Wilhelm
Transport characteristics of endomorphin-2 analogues in brain capillary endothelial cells.
Mariusz Sacharczuk; Bogdan Sadowski; Hanna Szymanska; Anna Lesniak; Agnieszka R Ragan; Andrzej W Lipkowski
Distinct susceptibility to inoculated melanoma and sensitivity to cancer pain in mouse lines with high and low sensitivity to stress.

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All Publications

2012: Sergiusz Markowicz; Aleksandra Misicka; Zbigniew I Nowecki; Hanna Polowniak-Pracka; Piotr Rutkowski; Henryk Skurzak; Tomasz Switaj; Marzena Biernacka; Anna Jakubowska-Mucka; Andrzej W Lipkowski; Jan Walewski
Adjuvant vaccination with melanoma antigen-pulsed dendritic cells in stage III melanoma patients.
Medical oncology (Northwood, London, England) 2012;29(4):2966-77.
2012: Jayapal Reddy Mallareddy; Judit Molnár; Péter Nagyőszi; Géza Tóth; Csilla Fazakas; István A Krizbai; Andrzej W Lipkowski; Imola Wilhelm
Transport characteristics of endomorphin-2 analogues in brain capillary endothelial cells.
Chemical biology & drug design 2012;79(4):507-13.
2012: Mariusz Sacharczuk; Bogdan Sadowski; Hanna Szymanska; Anna Lesniak; Agnieszka R Ragan; Andrzej W Lipkowski
Distinct susceptibility to inoculated melanoma and sensitivity to cancer pain in mouse lines with high and low sensitivity to stress.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 2012;31(2):167-77.
2012: Karel Guillemyn; Patrycja Kleczkowska; Piotr Kosson; Andrzej W Lipkowski; Alexandre Novoa; Peter W Schiller; Mariana Spetea; Dirk Tourwé; Isabelle Van den Eynde; Bart Vandormael; Muhammad Faheem Asim; Steven Ballet
In vivo antinociception of potent mu opioid agonist tetrapeptide analogues and comparison with a compact opioid agonist-neurokinin 1 receptor antagonist chimera.
Molecular brain 2012;5():4.
2011: Maria Kawalec; Joanna E Kowalczyk; Andrzej W Lipkowski; Malgorzata Beresewicz; Barbara Zablocka
Neuroprotective potential of biphalin, multireceptor opioid peptide, against excitotoxic injury in hippocampal organotypic culture.
Neurochemical research 2011;36(11):2091-5.
2011: Yuko Yamada; Kousaku Ohinata; Andrzej W Lipkowski; Masaaki Yoshikawa
Rapakinin, Arg-Ile-Tyr, derived from rapeseed napin, shows anti-opioid activity via the prostaglandin IP receptor followed by the cholecystokinin CCK(2) receptor in mice.
Peptides 2011;32(2):281-5.
2011: Anna Lesniak; Andrzej W Lipkowski
Opioid peptides in peripheral pain control.
Acta neurobiologiae experimentalis 2011;71(1):129-38.
2010: Marzena Lazarczyk; Ewa Matyja; Andrzej W Lipkowski
A comparative study of morphine stimulation and biphalin inhibition of human glioblastoma T98G cell proliferation in vitro.
Peptides 2010;31(8):1606-12.
2010: Yuko Yamada; Masashi Iwasaki; Hachiro Usui; Kousaku Ohinata; Ewa D Marczak; Andrzej W Lipkowski; Masaaki Yoshikawa
Rapakinin, an anti-hypertensive peptide derived from rapeseed protein, dilates mesenteric artery of spontaneously hypertensive rats via the prostaglandin IP receptor followed by CCK(1) receptor.
Peptides 2010;31(5):909-14.
2010: Mariusz Sacharczuk; Bogdan Sadowski; Kazimierz Jaszczak; Andrzej W Lipkowski; Artur H Swiergiel
Opposite effects of alcohol in regulating stress-induced changes in body weight between the two mouse lines with enhanced or low opioid system activity.
Physiology & behavior 2010;99(5):627-31.
2010: Patrycja Kleczkowska; Piotr Kosson; Steven Ballet; Isabelle Van den Eynde; Yuko Tsuda; Dirk Tourwé; Andrzej W Lipkowski
PK20, a new opioid-neurotensin hybrid peptide that exhibits central and peripheral antinociceptive effects.
Molecular pain 2010;6():86.
2009: Marcin Jurga; Andrzej W Lipkowski; Barbara Lukomska; Leonora Buzanska; Katarzyna Kurzepa; Tomasz Sobanski; Aleksandra Habich; Sandra Coecke; Barbara Gajkowska; Krystyna Domanska-Janik
Generation of functional neural artificial tissue from human umbilical cord blood stem cells.
Tissue engineering. Part C, Methods 2009;15(3):365-72.
2009: Monika Lukowiak; Piotr Kosson; Wim E Hennink; Andrzej W Lipkowski
Synthesis and pharmacological properties of a new fluorescent opioid peptide analog.
Pharmacological reports : PR 2009;61(4):727-31.
2009: Yuko Yamada; Kousaku Ohinata; Andrzej W Lipkowski; Masaaki Yoshikawa
Angiotensin AT(2) receptor agonists act as anti-opioids via EP(3) receptor in mice.
Peptides 2009;30(4):735-9.
2009: Mariusz Sacharczuk; Grzegorz R Juszczak; Artur H Swiergiel; Kazimierz Jaszczak; Andrzej W Lipkowski; Bogdan Sadowski
Alcohol reverses depressive and pronociceptive effects of chronic stress in mice with enhanced activity of the opioid system.
Acta neurobiologiae experimentalis 2009;69(4):459-68.
2009: Barbara Kwiatkowska-Patzer; Jacek Michałkiewicz; Izabela Kubiszewska; Joanna Zielińska; Kaja Kasarello; Katarzyna Kurzepa; Andrzej W Lipkowski
Spinal cord hydrolysate ameliorate immunological reaction in experimental allergic encephalomyelitis.
Acta neurobiologiae experimentalis 2009;69(1):73-8.
2008: Mariusz Sacharczuk; Grzegorz Juszczak; Adam T Sliwa; Agnieszka Tymosiak-Zielinska; Pawel Lisowski; Kazimierz Jaszczak; Ryszard Pluta; Andrzej W Lipkowski; Bogdan Sadowski; Artur H Swiergiel
Differences in ethanol drinking between mice selected for high and low swim stress-induced analgesia.
Alcohol (Fayetteville, N.Y.) 2008;42(6):487-92.
2008: Dariusz Kosson; Anna Klinowiecka; Piotr Kosson; Iwona Bonney; Daniel B Carr; Ewa Mayzner-Zawadzka; Andrzej W Lipkowski
Intrathecal antinociceptive interaction between the NMDA antagonist ketamine and the opioids, morphine and biphalin.
European journal of pain (London, England) 2008;12(5):611-6.
2008: Steven Ballet; Aleksandra Misicka; Piotr Kosson; Carole Lemieux; Nga N Chung; Peter W Schiller; Andrzej W Lipkowski; Dirk Tourwé
Blood-brain barrier penetration by two dermorphin tetrapeptide analogues: role of lipophilicity vs structural flexibility.
Journal of medicinal chemistry 2008;51(8):2571-4.
2008: Jie-Liu Tang; Andrzej W Lipkowski; Steven Specter
Molecular assessment of the potential combination therapy of cytokines with biphalin and AZT for Friend leukemia virus infection in vitro.
Pharmacological reports : PR 2008;60(2):190-8.
2007: Piotr Wojciechowski; Malgorzata Szereda-Przestaszewska; Andrzej W Lipkowski
Supranodose vagotomy eliminates respiratory depression evoked by dermorphin in anaesthetized rats.
European journal of pharmacology 2007;563(1-3):209-12.
2006: Ewa D Marczak; Kousaku Ohinata; Andrzej W Lipkowski; Masaaki Yoshikawa
Arg-Ile-Tyr (RIY) derived from rapeseed protein decreases food intake and gastric emptying after oral administration in mice.
Peptides 2006;27(9):2065-8.
2005: Bozena Szaniawska; P Kleczkowska; Halina Trembacz; Przemyslaw Janik; Andrzej W Lipkowski
A novel fibronectin-related structural motif that modulates cell migration.
The journal of peptide research : official journal of the American Peptide Society 2005;66 Suppl 1():114-9.
2005: Steven Ballet; A Frycia; J Piron; Nga N Chung; Peter W Schiller; Piotr Kosson; Andrzej W Lipkowski; Dirk Tourwé
Synthesis and biological evaluation of constrained analogues of the opioid peptide H-Tyr-D-Ala-Phe-Gly-NH2 using the 4-amino-2-benzazepin-3-one scaffold.
The journal of peptide research : official journal of the American Peptide Society 2005;66(5):222-30.
2005: Piotr Kosson; Iwona Bonney; Daniel B Carr; Andrzej W Lipkowski
Endomorphins interact with tachykinin receptors.
Peptides 2005;26(9):1667-9.
2005: Dariusz Kosson; Iwona Bonney; Daniel B Carr; Ewa Mayzner-Zawadzka; Andrzej W Lipkowski
Antinociception after intrathecal biphalin application in rats: a reevaluation and novel, rapid method to confirm correct catheter tip position.
Pharmacological reports : PR 2005;57(4):545-9.
2005: Isabelle Van den Eynde; Georges Laus; Peter W Schiller; Piotr Kosson; Nga N Chung; Andrzej W Lipkowski; Dirk Tourwé
A new structural motif for mu-opioid antagonists.
Journal of medicinal chemistry 2005;48(10):3644-8.
2005: Emanuela Sperlinga; Piotr Kosson; Zofia Urbanczyk-Lipkowska; Giuseppe Ronsisvalle; Daniel B Carr; Andrzej W Lipkowski
6-Hydroxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid mimics active conformation of tyrosine in opioid peptides.
Bioorganic & medicinal chemistry letters 2005;15(10):2467-9.
2004: Iwona Bonney; Stacy E Foran; James E Marchand; Andrzej W Lipkowski; Daniel B Carr
Spinal antinociceptive effects of AA501, a novel chimeric peptide with opioid receptor agonist and tachykinin receptor antagonist moieties.
European journal of pharmacology 2004;488(1-3):91-9.
2004: Iwona Maszczynska Bonney; Dilek Sendil Keskin; Andrzej W Lipkowski; Vasif Hasirci; Daniel B Carr
Advances in analgesic drug design and delivery: a current survey.
Advances in experimental medicine and biology 2004;553():209-19.
2004: Barbara Kwiatkowska-Patzer; Michal Walski; Malgorzata Frontczak-Baniewicz; Teresa Zalewska; Bozena Baranowska; Andrzej W Lipkowski
Matrix metalloproteases activity and ultrastructural changes in the early phase of experimental allergic encephalomyelitis. The effect of oral treatment with spinal cord hydrolysate [correction of hydrolisate] proteins in Lewis rat. The pilot study.
Folia neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences 2004;42(2):107-11.
2004: Andrzej W Lipkowski; Daniel B Carr; Victor J Hruby; Masaaki Yoshikawa
Is RNA-laden p24 capsid protein a vector for HIV?
Medical hypotheses 2004;62(6):919-21.
2003: Jolanta Janiszewska; Joanna Swieton; Andrzej W Lipkowski; Zofia Urbanczyk-Lipkowska
Low molecular mass peptide dendrimers that express antimicrobial properties.
Bioorganic & medicinal chemistry letters 2003;13(21):3711-3.
2003: A Olma; M Łachwa; Andrzej W Lipkowski
The biological consequences of replacing hydrophobic amino acids in deltorphin I with amphiphilic alpha-hydroxymethylamino acids.
The journal of peptide research : official journal of the American Peptide Society 2003;62(1):45-52.
2003: Ewa D Marczak; Hachiro Usui; Hiroyuki Fujita; Yanjun Yang; Megumi Yokoo; Andrzej W Lipkowski; Masaaki Yoshikawa
New antihypertensive peptides isolated from rapeseed.
Peptides 2003;24(6):791-8.
2003: V Boguslavsky; Victor J Hruby; David F O'Brien; Aleksandra Misicka; Andrzej W Lipkowski
Effect of peptide conformation on membrane permeability.
The journal of peptide research : official journal of the American Peptide Society 2003;61(6):287-97.
2003: Yasuyuki Takenaka; F Nakamura; Hachiro Usui; Andrzej W Lipkowski; G Toth; Masaaki Yoshikawa
Anti-analgesic activity of enterostatin (VPDPR) is mediated by corticosterone.
Peptides 2003;24(5):735-9.
2003: Dilek Sendil; Iwona Bonney; Daniel B Carr; Andrzej W Lipkowski; Donald L Wise; Vasif Hasirci
Antinociceptive effects of hydromorphone, bupivacaine and biphalin released from PLGA polymer after intrathecal implantation in rats.
Biomaterials 2003;24(11):1969-76.
2003: Barbara Oderfeld-Nowak; Malgorzata Zaremba; Andrzej W Lipkowski; Barbara Kwiatkowska-Patzer; V Triaca; L Aloe
High-affinity NGF receptor in the rat spinal cord during acute and chronic phases of experimental autoimmune encephalomyelitis: a possible functional significance.
Archives italiennes de biologie 2003;141(2-3):103-16.
2003: Barbara Kwiatkowska-Patzer; Bozena Baranowska; Michal Walski; Andrzej W Lipkowski
Influence of spinal cord protein hydrolysate upon the blood brain barrier changes due to experimental allergic encephalomyelitis in Lewis rats. Ultrastructural study.
Folia neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences 2003;41(1):29-34.
2002: Vincent S Hau; Jason D Huber; Christopher R Campos; Andrzej W Lipkowski; Aleksandra Misicka; Thomas P Davis
Effect of guanidino modification and proline substitution on the in vitro stability and blood-brain barrier permeability of endomorphin II.
Journal of pharmaceutical sciences 2002;91(10):2140-9.
2002: Katarzyna Kowalska; Daniel B Carr; Andrzej W Lipkowski
Direct antimicrobial properties of substance P.
Life sciences 2002;71(7):747-50.
2002: Judith L Flippen-Anderson; Jeffrey Deschamps; Clifford George; V J Hruby; Aleksandra Misicka; Andrzej W Lipkowski
Crystal structure of biphalin sulfate: a multireceptor opioid peptide.
The journal of peptide research : official journal of the American Peptide Society 2002;59(3):123-33.
2002: Andrzej W Lipkowski; Aleksandra Misicka; Dariusz Kosson; Piotr Kosson; Magdalena Lachwa-From; Agnieszka Brodzik-Bienkowska; Victor J Hruby
Biological properties of a new fluorescent biphalin fragment analogue.
Life sciences 2002;70(8):893-7.
2001: Shuzhang Yang; J Yunden; Soushi Sonoda; Naomi Doyama; Andrzej W Lipkowski; Yukio Kawamura; Masaaki Yoshikawa
Rubiscolin, a delta selective opioid peptide derived from plant Rubisco.
FEBS letters 2001;509(2):213-7.
2001: Bozena Szaniawska; Halina Trembacz; Joanna Miloszewska; Andrzej W Lipkowski; Aleksandra Misicka; J Ostrowski; Przemyslaw Janik
Peptide analog of fibronectin that inhibits cell migration and ERK 1/2 activity.
Peptides 2001;22(12):1949-53.
2001: Andrzej W Lipkowski; Aleksandra Misicka; Keiko Hosohata; Peg Davis; Henry I Yamamura; Frank Porreca; Victor J Hruby
Biological properties of Phe(o)-opioid peptide analogues.
Life sciences 2001;68(8):969-72.
2001: A Olma; A Gniadzik; Andrzej W Lipkowski; M Lachwa
Synthesis and binding properties of deltorphin I analogues containing (R) and (S)-alpha-hydroxymethylnaphtylalanine.
Acta biochimica Polonica 2001;48(4):1165-8.
2000: Stacy E Foran; Daniel B Carr; Andrzej W Lipkowski; I Maszczynska; James E Marchand; Aleksandra Misicka; Martin Beinborn; Alan Kopin; RM Kream
Inhibition of morphine tolerance development by a substance P-opioid peptide chimera.
The Journal of pharmacology and experimental therapeutics 2000;295(3):1142-8.
2000: M Maksymowicz; Dariusz Kosson; Andrzej W Lipkowski; Waldemar L Olszewski
Influence of opioids on lymphocyte circulation and homing.
Transplantation proceedings 2000;32(6):1395-6.
2000: Ryszard Pluta; Aleksandra Misicka; Maria Barcikowska; S Spisacka; Andrzej W Lipkowski; S Januszewski
Possible reverse transport of beta-amyloid peptide across the blood-brain barrier.
Acta neurochirurgica. Supplement 2000;76():73-7.
2000: Andrzej W Lipkowski; Bozena Baranowska; Ewa D Marczak; Barbara Kwiatkowska-Patzer; B Gajkowska; Michal Walski
Protein hydrolysates for oral tolerance.
BioFactors (Oxford, England) 2000;12(1-4):147-50.
1999: Ryszard Pluta; Maria Barcikowska; Aleksandra Misicka; Andrzej W Lipkowski; S Spisacka; S Januszewski
Ischemic rats as a model in the study of the neurobiological role of human beta-amyloid peptide. Time-dependent disappearing diffuse amyloid plaques in brain.
Neuroreport 1999;10(17):3615-9.
1999: Andrzej W Lipkowski; Aleksandra Misicka; Peg Davis; Dagmar Stropova; J Janders; M Lachwa; Frank Porreca; Henry I Yamamura; Victor J Hruby
Biological activity of fragments and analogues of the potent dimeric opioid peptide, biphalin.
Bioorganic & medicinal chemistry letters 1999;9(18):2763-6.
1998: G Li; W Haq; L Xiang; B S Lou; R Hughes; I A De Leon; Peg Davis; TJ Gillespie; Marek Romanowski; Xiaoyun Zhu; Aleksandra Misicka; Andrzej W Lipkowski; Frank Porreca; Thomas P Davis; Henry I Yamamura; David F O'Brien; Victor J Hruby
Modifications of the 4,4'-residues and SAR studies of Biphalin, a highly potent opioid receptor active peptide.
Bioorganic & medicinal chemistry letters 1998;8(5):555-60.
1998: Barbara Kwiatkowska-Patzer; B Gajkowska; Bozena Baranowska; Andrzej W Lipkowski
Ultrastructural changes in the central and peripheral nervous system in the rat with experimental allergic encephalomyelitis.
Folia neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences 1998;36(4):244-8.
1998: J Slaninova; Suzanne M Appleyard; Aleksandra Misicka; Andrzej W Lipkowski; Richard J Knapp; S J Weber; Thomas P Davis; Henry I Yamamura; Victor J Hruby
[125I-Tyr1]biphalin binding to opioid receptors of rat brain and NG108-15 cell membranes.
Life sciences 1998;62(14):PL199-204.
1997: Marek Romanowski; Xiaoyun Zhu; V Ramaswami; Aleksandra Misicka; Andrzej W Lipkowski; Victor J Hruby; David F O'Brien
Interaction of a highly potent dimeric enkephalin analog, biphalin, with model membranes.
Biochimica et biophysica acta 1997;1329(2):245-58.
1997: Ryszard Pluta; Aleksandra Misicka; S Januszewski; Maria Barcikowska; Andrzej W Lipkowski
Transport of human beta-amyloid peptide through the rat blood-brain barrier after global cerebral ischemia.
Acta neurochirurgica. Supplement 1997;70():247-9.
1997: Aleksandra Misicka; Andrzej W Lipkowski; R Horvath; Peg Davis; Frank Porreca; Henry I Yamamura; Victor J Hruby
Structure-activity relationship of biphalin. The synthesis and biological activities of new analogues with modifications in positions 3 and 4.
Life sciences 1997;60(15):1263-9.
1996: V Ramaswami; X Zhu; Marek Romanowski; R C Haaseth; Aleksandra Misicka; Andrzej W Lipkowski; Victor J Hruby; David F O'Brien
Lipid membrane permeability of modified c[D-Pen2, D-Pen5]enkephalin peptides.
International journal of peptide and protein research 1996;48(1):87-94.
1996: D L Greene; Vincent S Hau; Thomas J Abbruscato; H Bartosz; Aleksandra Misicka; Andrzej W Lipkowski; S Hom; TJ Gillespie; Victor J Hruby; Thomas P Davis
Enkephalin analog prodrugs: assessment of in vitro conversion, enzyme cleavage characterization and blood-brain barrier permeability.
The Journal of pharmacology and experimental therapeutics 1996;277(3):1366-75.
1996: Ryszard Pluta; Maria Barcikowska; S Januszewski; Aleksandra Misicka; Andrzej W Lipkowski
Evidence of blood-brain barrier permeability/leakage for circulating human Alzheimer's beta-amyloid-(1-42)-peptide.
Neuroreport 1996;7(7):1261-5.
1996: Thomas J Abbruscato; S A Williams; Aleksandra Misicka; Andrzej W Lipkowski; Victor J Hruby; Thomas P Davis
Blood-to-central nervous system entry and stability of biphalin, a unique double-enkephalin analog, and its halogenated derivatives.
The Journal of pharmacology and experimental therapeutics 1996;276(3):1049-57.
1996: Aleksandra Misicka; I Maszczynska; Andrzej W Lipkowski; Dagmar Stropova; Henry I Yamamura; V J Hruby
Synthesis and biological properties of gamma-glutamyl-dermorphin, a prodrug.
Life sciences 1996;58(11):905-11.
1995: W M Kazmierski; R D Ferguson; Andrzej W Lipkowski; Victor J Hruby
A topographical model of mu-opioid and brain somatostatin receptor selective ligands. NMR and molecular dynamics studies.
International journal of peptide and protein research 1995;46(3-4):265-78.
1995: Aleksandra Misicka; Andrzej W Lipkowski; J Slaninova; P Davis; Henry I Yamamura; F Porreca; Victor J Hruby
The synthesis and opioid receptor binding affinities of analogues of dermorphin and its N-terminal tetrapeptide fragment with dibasic acids in position 2.
Life sciences 1995;57(18):1633-40.
1994: Aleksandra Misicka; Andrzej W Lipkowski; R Horvath; P Davis; F Porreca; Henry I Yamamura; Victor J Hruby
Delta opioid receptor selective ligands; DPLPE-deltorphin chimeric peptide analogues.
International journal of peptide and protein research 1994;44(6):607.
1994: Aleksandra Misicka; Andrzej W Lipkowski; R Horvath; P Davis; F Porreca; Henry I Yamamura; Victor J Hruby
Delta opioid receptor selective ligands; DPLPE-deltorphin chimeric peptide analogues.
International journal of peptide and protein research 1994;44(1):80-4.
1994: Aleksandra Misicka; Andrzej W Lipkowski; R Horvath; P Davis; Henry I Yamamura; F Porreca; Victor J Hruby
Design of cyclic deltorphins and dermenkephalins with a disulfide bridge leads to analogues with high selectivity for delta-opioid receptors.
Journal of medicinal chemistry 1994;37(1):141-5.
1994: A Langlade; Daniel B Carr; Alain Serrie; B S Silbert; S K Szyfelbein; Andrzej W Lipkowski
Enhanced potency of intravenous, but not intrathecal, morphine and morphine-6-glucuronide after burn trauma.
Life sciences 1994;54(22):1699-709.
1994: Andrzej W Lipkowski; Daniel B Carr; A Langlade; P F Osgood; S K Szyfelbein
Morphine-3-glucuronide: silent regulator of morphine actions.
Life sciences 1994;55(2):149-54.
1994: Andrzej W Lipkowski; Daniel B Carr; B S Silbert; M S Cepeda; P F Osgood; S K Szyfelbein
Non-deterministic individual responses to receptor-selective opioid agonists.
Polish journal of pharmacology 1994;46(1-2):29-35.
1994: K Misterek; I Maszczynska; A Dorociak; S W Gumulka; D B Carr; S K Szyfelbein; Andrzej W Lipkowski
Spinal co-administration of peptide substance P antagonist increases antinociceptive effect of the opioid peptide biphalin.
Life sciences 1994;54(14):939-44.
1993: S J Weber; Thomas J Abbruscato; E A Brownson; Andrzej W Lipkowski; Robin Polt; Aleksandra Misicka; R C Haaseth; H Bartosz; Victor J Hruby; Thomas P Davis
Assessment of an in vitro blood-brain barrier model using several [Met5]enkephalin opioid analogs.
The Journal of pharmacology and experimental therapeutics 1993;266(3):1649-55.
1993: K D Wild; P J Horan; Aleksandra Misicka; Andrzej W Lipkowski; R C Haaseth; T O Matsunaga; Victor J Hruby; G Toth; A Borsodi; Henry I Yamamura
Pseudoirreversible binding characteristics of [D-Ala2,Glu4]deltorphin and its Cys4 substituted derivative to delta-opioid receptors.
European journal of pharmacology 1993;246(1):25-31.
1993: P J Horan; K D Wild; Aleksandra Misicka; Andrzej W Lipkowski; R C Haaseth; Victor J Hruby; S J Weber; Thomas P Davis; Henry I Yamamura; F Porreca
Agonist and antagonist profiles of [D-Ala2,Glu4]deltorphin and its [Cys4]- and [Ser4]-substituted derivatives: further evidence of opioid delta receptor multiplicity.
The Journal of pharmacology and experimental therapeutics 1993;265(2):896-902.
1993: M S Cepeda; Andrzej W Lipkowski; A Langlade; P F Osgood; H P Ehrlich; Kenneth Hargreaves; S K Szyfelbein; Daniel B Carr
Local increases of subcutaneous beta-endorphin immunoactivity at the site of thermal injury.
Immunopharmacology 1993;25(3):205-13.
1992: Aleksandra Misicka; Andrzej W Lipkowski; R Horvath; P Davis; T H Kramer; Henry I Yamamura; Victor J Hruby
Topographical requirements for delta opioid ligands: common structural features of dermenkephalin and deltorphin.
Life sciences 1992;51(13):1025-32.
1992: Andrzej W Lipkowski; K Misterek
Bifunctional pharmacophores. Biological activities of the peptide analog containing both casomorphine-like and substance P antagonist-like active elements.
Polish journal of pharmacology and pharmacy 1992;44(1):25-32.
1991: Janusz Stepinski; I Zajaczkowski; D Kazem-Bek; A Temeriusz; Andrzej W Lipkowski; S W Tam
Use of hydrophilic diamines for bridging of two opioid peptide pharmacophores. Synthesis and receptor binding of two new analogues.
International journal of peptide and protein research 1991;38(6):588-92.
1991: Aleksandra Misicka; Andrzej W Lipkowski; L Fang; Richard J Knapp; P Davis; T Kramer; T F Burks; Henry I Yamamura; D B Carr; Victor J Hruby
Topographical requirements for delta opioid ligands: presence of a carboxyl group in position 4 is not critical for deltorphin high delta receptor affinity and analgesic activity.
Biochemical and biophysical research communications 1991;180(3):1290-7.
1991: B S Silbert; Andrzej W Lipkowski; M S Cepeda; S K Szyfelbein; P F Osgood; Daniel B Carr
Enhanced potency of receptor-selective opioids after acute burn injury.
Anesthesia and analgesia 1991;73(4):427-33.
1991: B S Silbert; Andrzej W Lipkowski; M S Cepeda; S K Szyfelbein; P F Osgood; Daniel B Carr
Analgesic activity of a novel bivalent opioid peptide compared to morphine via different routes of administration.
Agents and actions 1991;33(3-4):382-7.
1990: B S Silbert; Andrzej W Lipkowski; Daniel B Carr; S K Szyfelbein; P F Osgood
Peptides as potential antinociceptive drugs.
Progress in clinical and biological research 1990;328():485-8.
1987: Andrzej W Lipkowski
Cooperative reinforcement of opioid pharmacophores.
Polish journal of pharmacology and pharmacy 1987;39(5):585-96.