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Brian Lipworth

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TOP 3
Brian J Lipworth; Philip M Short
Explaining differential effects of tiotropium on mortality in COPD.
Brian J Lipworth; Donald F Macgregor; Kaninika Basu; Helen P Donald; Simon A Ogston; Colin N A Palmer; Roger Tavendale; Somnath Mukhopadhyay
Tailored second-line therapy in asthmatic children with the Arg(16) genotype.
Brian J Lipworth
Adrenal suppression with fluticasone furoate.

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All Publications

2013: Brian J Lipworth; Philip M Short
Explaining differential effects of tiotropium on mortality in COPD.
Thorax 2013;68(6):589-90.
2013: Brian J Lipworth; Donald F Macgregor; Kaninika Basu; Helen P Donald; Simon A Ogston; Colin N A Palmer; Roger Tavendale; Somnath Mukhopadhyay
Tailored second-line therapy in asthmatic children with the Arg(16) genotype.
Clinical science (London, England : 1979) 2013;124(8):521-8.
2013: Brian J Lipworth
Adrenal suppression with fluticasone furoate.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2013;110(3):213.
2013: Arvind Manoharan; William J Anderson; Brian J Lipworth
Influence of β(2)-adrenergic receptor polymorphism on methacholine hyperresponsiveness in asthmatic patients.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2013;110(3):161-4.
2013: Peter A Williamson; Philip M Short; Sriram Vaidyanathan; Brian J Lipworth
Inhaled and systemic corticosteroid response in severe asthma assessed by alveolar nitric oxide: a randomized crossover pilot study of add-on therapy.
British journal of clinical pharmacology 2013;75(1):93-102.
2012: Philip M Short; Peter A Williamson; Brian J Lipworth
Sensitivity of impulse oscillometry and spirometry in beta-blocker induced bronchoconstriction and beta-agonist bronchodilatation in asthma.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2012;109(6):412-5.
2012: William J Anderson; Brian J Lipworth
Relationship of mannitol challenge to methacholine challenge and inflammatory markers in persistent asthmatics receiving inhaled corticosteroids.
Lung 2012;190(5):513-21.
2012: William J Anderson; Emma Zajda; Brian J Lipworth
Are we overlooking persistent small airways dysfunction in community-managed asthma?
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2012;109(3):185-189.e2.
2012: Philip M Short; Peter A Williamson; Brian J Lipworth
Effects of extra-fine inhaled and oral corticosteroids on alveolar nitric oxide in COPD.
Lung 2012;190(4):395-401.
2012: Sriram Vaidyanathan; Peter A Williamson; Brian J Lipworth
Is a positive nasal lysine-aspirin challenge test associated with a more severe phenotype of chronic rhinosinusitis and asthma?
American journal of rhinology & allergy 2012;26(3):e89-93.
2012: Philip M Short; Peter A Williamson; Brian J Lipworth
Effects of hydrocortisone on acute β-adrenoceptor blocker and histamine induced bronchoconstriction.
British journal of clinical pharmacology 2012;73(5):717-26.
2012: William J Anderson; Brian J Lipworth
Does body mass index influence responsiveness to inhaled corticosteroids in persistent asthma?
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2012;108(4):237-42.
2012: Brian J Lipworth; Philip M Short; Peter A Williamson; Karine L Clearie; Tom C Fardon; Cathy M Jackson
A randomized primary care trial of steroid titration against mannitol in persistent asthma: STAMINA trial.
Chest 2012;141(3):607-15.
2012: Karine L Clearie; Lorna McKinlay; Peter A Williamson; Brian J Lipworth
Fluticasone/Salmeterol combination confers benefits in people with asthma who smoke.
Chest 2012;141(2):330-8.
2011: Philip M Short; Samuel I W Lipworth; Brian J Lipworth
Relationships between airway hyperresponsiveness, inflammation, and calibre in asthma.
Lung 2011;189(6):493-7.
2011: Arun Nair; Julia Ward; Brian J Lipworth
Comparison of bronchodilator response in patients with asthma and healthy subjects using spirometry and oscillometry.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2011;107(4):317-22.
2011: P A Williamson; S Vaidyanathan; M Barnes; K Clearie; Brian J Lipworth
Airway dysfunction in nasal polyposis: a spectrum of asthmatic disease?
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2011;41(10):1379-85.
2011: P A Williamson; P M Short; L McKinlay; C N A Palmer; Brian J Lipworth
β-agonist safety and the elephant in the room?
Thorax 2011;66(6):542; author reply 542-3.
2011: Karine L Clearie; Peter A Williamson; Karen Meldrum; Michael Gillen; Lars-Goran Carlsson; Marie Carlholm; Jan Ekelund; Brian J Lipworth
Pharmacokinetic and pharmacodynamic comparison of hydrofluoroalkane and chlorofluorocarbon formulations of budesonide.
British journal of clinical pharmacology 2011;71(4):504-13.
2011: Arun Nair; Lorna McKinlay; Peter Williamson; Philip Short; Patricia Burns; Brian J Lipworth
Comparative lung bioavailability of fluticasone/salmeterol via a breath-actuated spacer and conventional plastic spacers.
European journal of clinical pharmacology 2011;67(4):355-63.
2011: Peter A Williamson; Karine Clearie; Daniel Menzies; Sriram Vaidyanathan; Brian J Lipworth
Assessment of small-airways disease using alveolar nitric oxide and impulse oscillometry in asthma and COPD.
Lung 2011;189(2):121-9.
2011: K L Clearie; Catherine M Jackson; Tom C Fardon; P A Williamson; S Vaidyanathan; P Burns; Brian J Lipworth
Supervised step-down of inhaled corticosteroids in the community--an observational study.
Respiratory medicine 2011;105(4):558-65.
2011: Philip M Short; Samuel I W Lipworth; Douglas H J Elder; Stuart Schembri; Brian J Lipworth
Effect of beta blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study.
BMJ (Clinical research ed.) 2011;342():d2549.
2011: Lorna McKinlay; Peter A Williamson; Philip M Short; Tom C Fardon; Brian J Lipworth
Proof of concept study to evaluate step-down therapy with inhaled corticosteroid alone or additive therapy on surrogate inflammatory markers in asthma.
British journal of clinical pharmacology 2011;71(1):128-31.
2010: Peter A Williamson; Philip M Short; Karine L Clearie; Sriram Vaidyanathan; Tom C Fardon; Laura J Howaniec; Brian J Lipworth
Paradoxical trough effects of triple therapy with budesonide/formoterol and tiotropium bromide on pulmonary function outcomes in COPD.
Chest 2010;138(3):595-604.
2010: Peter A Williamson; Sriram Vaidyanathan; Karine Clearie; Munro Stewart; Brian J Lipworth
Relationship between fractional exhaled nitric oxide and nasal nitric oxide in airways disease.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2010;105(2):162-7.
2010: Karine L Clearie; Peter A Williamson; Sriram Vaidyanathan; Jeannine Du Bois; Haylene Nell; Brian J Lipworth
Systemic bioavailability of hydrofluoroalkane (HFA) formulations of fluticasone/salmeterol in healthy volunteers via pMDI alone and spacer.
British journal of clinical pharmacology 2010;69(6):637-44.
2010: K L Clearie; P A Williamson; S Vaidyanathan; P Short; A Goudie; Patricia Burns; P Hopkinson; K Meldrum; L Howaniec; Brian J Lipworth
Disconnect between standardized field-based testing and mannitol challenge in Scottish elite swimmers.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2010;40(5):731-7.
2010: A Nair; S Vaidyanathan; K Clearie; P Williamson; K Meldrum; Brian J Lipworth
Steroid sparing effects of intranasal corticosteroids in asthma and allergic rhinitis.
Allergy 2010;65(3):359-67.
2010: Martyn L Barnes; S Vaidyanathan; P A Williamson; Brian J Lipworth
The minimal clinically important difference in allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2010;40(2):242-50.
2010: K L Clearie; S Vaidyanathan; P A Williamson; A Goudie; P Short; S Schembri; Brian J Lipworth
Effects of chlorine and exercise on the unified airway in adolescent elite Scottish swimmers.
Allergy 2010;65(2):269-73.
2010: Brian J Lipworth; Peter A Williamson
Think the impossible: beta-blockers for treating asthma.
Clinical science (London, England : 1979) 2010;118(2):115-20.
2009: Kaninika Basu; Arun Nair; Peter A Williamson; Somnath Mukhopadhyay; Brian J Lipworth
Airway and systemic effects of soluble and suspension formulations of nebulized budesonide in asthmatic children.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2009;103(5):436-41.
2009: Arun Nair; Karine Clearie; Daniel Menzies; Karen Meldrum; Lesley C McFarlane; Brian J Lipworth
A novel breath-actuated integrated vortex spacer device increases relative lung bioavailability of fluticasone/salmeterol in combination.
Pulmonary pharmacology & therapeutics 2009;22(4):305-10.
2009: P A Williamson; K Clearie; S Vaidyanathan; Brian J Lipworth
Effects of methacholine challenge on alveolar nitric oxide.
Thorax 2009;64(6):549-50.
2009: S Vaidyanathan; A Nair; Martyn L Barnes; K Meldrum; Brian J Lipworth
Effect of levocetirizine on nasal provocation testing with adenosine monophosphate compared with allergen challenge in allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(3):409-16.
2009: Peter A Williamson; Daniel Menzies; Arun Nair; Ahmet Tutuncu; Brian J Lipworth
A proof-of-concept study to evaluate the antiinflammatory effects of a novel soluble cyclodextrin formulation of nebulized budesonide in patients with mild to moderate asthma.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2009;102(2):161-7.
2009: Arun Nair; Daniel Menzies; Pippa Hopkinson; Lesley C McFarlane; Brian J Lipworth
In vivo comparison of the relative systemic bioavailability of fluticasone propionate from three anti-static spacers and a metered dose inhaler.
British journal of clinical pharmacology 2009;67(2):191-8.
2009: Brian J Lipworth; Peter A Williamson
Beta blockers for asthma: a double-edged sword.
Lancet 2009;373(9658):104-5.
2009: Sriram Vaidyanathan; Martyn Barnes; Brian J Lipworth
Comparative safety and efficacy of 2 formulations of fluticasone aqueous nasal spray in persistent allergic rhinitis.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2009;102(1):76-83.
2008: Daniel Menzies; Cathy Jackson; Catrina Mistry; Ruth Houston; Brian J Lipworth
Symptoms, spirometry, exhaled nitric oxide, and asthma exacerbations in clinical practice.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2008;101(3):248-55.
2008: Kaninika Basu; Colin N A Palmer; Brian J Lipworth; W H Irwin McLean; Ana Terron-Kwiatkowski; Yiwei Zhao; Haihui Liao; Frances J D Smith; A Mitra; Somnath Mukhopadhyay
Filaggrin null mutations are associated with increased asthma exacerbations in children and young adults.
Allergy 2008;63(9):1211-7.
2008: Arun Nair; Daniel Menzies; Martyn Barnes; Patricia Burns; Lesley C McFarlane; Brian J Lipworth
Respirable dose delivery of fluticasone propionate from a small valved holding chamber, a compact breath actuated integrated vortex device and a metered dose inhaler.
British journal of clinical pharmacology 2008;66(1):20-6.
2008: Daniel Menzies; Arun Nair; Karen T Meldrum; Pippa Hopkinson; Brian J Lipworth
Effect of aspirin on airway inflammation and pulmonary function in patients with persistent asthma.
The Journal of allergy and clinical immunology 2008;121(5):1184-1189.e4.
2007: Zia R Tayab; Tom C Fardon; Daniel K C Lee; Kay Haggart; Lesley C McFarlane; Brian J Lipworth; Günther Hochhaus
Pharmacokinetic/pharmacodynamic evaluation of urinary cortisol suppression after inhalation of fluticasone propionate and mometasone furoate.
British journal of clinical pharmacology 2007;64(5):698-705.
2007: Martyn L Barnes; Brian J Lipworth
Removing nasal valve obstruction in peak nasal inspiratory flow measurement.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2007;99(1):59-60.
2007: Daniel Menzies; A Nair; P Hopkinson; Lesley C McFarlane; Brian J Lipworth
Differential anti-inflammatory effects of large and small particle size inhaled corticosteroids in asthma.
Allergy 2007;62(6):661-7.
2007: Brian J Lipworth
Long-acting beta2-adrenoceptor agonists: a smart choice for asthma?
Trends in pharmacological sciences 2007;28(6):257-62.
2007: Tom C Fardon; Kay Haggart; Daniel K C Lee; Brian J Lipworth
A proof of concept study to evaluate stepping down the dose of fluticasone in combination with salmeterol and tiotropium in severe persistent asthma.
Respiratory medicine 2007;101(6):1218-28.
2007: Daniel Menzies; Arun Nair; Tom C Fardon; Martyn Barnes; Patricia Burns; Brian J Lipworth
An in vivo and in vitro comparison of inhaled steroid delivery via a novel vortex actuator and a conventional valved holding chamber.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2007;98(5):471-9.
2007: Martyn L Barnes; Daniel Menzies; A R Nair; P J Hopkinson; Brian J Lipworth
A proof-of-concept study to assess the putative dose response to topical corticosteroid in persistent allergic rhinitis using adenosine monophosphate challenge.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2007;37(5):696-703.
2007: Daniel Menzies; Arun Nair; Karen T Meldrum; Dawn Fleming; Martyn Barnes; Brian J Lipworth
Simvastatin does not exhibit therapeutic anti-inflammatory effects in asthma.
The Journal of allergy and clinical immunology 2007;119(2):328-35.
2007: Martyn L Barnes; Daniel Menzies; Tom C Fardon; Patricia Burns; Andrew M Wilson; Brian J Lipworth
Combined mediator blockade or topical steroid for treating the unified allergic airway.
Allergy 2007;62(1):73-80.
2006: Martyn L Barnes; B T Biallosterski; S Fujihara; Robert D Gray; Tom C Fardon; Brian J Lipworth
Effects of intranasal corticosteroid on nasal adenosine monophosphate challenge in persistent allergic rhinitis.
Allergy 2006;61(11):1319-25.
2006: Colin N A Palmer; Brian J Lipworth; S Lee; Tahmina Ismail; Donald F Macgregor; Somnath Mukhopadhyay
Arginine-16 beta2 adrenoceptor genotype predisposes to exacerbations in young asthmatics taking regular salmeterol.
Thorax 2006;61(11):940-4.
2006: Daniel Menzies; Arun Nair; Peter A Williamson; Stuart Schembri; Mudher Z H Al-Khairalla; Martyn Barnes; Tom C Fardon; Lesley C McFarlane; Gareth J Magee; Brian J Lipworth
Respiratory symptoms, pulmonary function, and markers of inflammation among bar workers before and after a legislative ban on smoking in public places.
JAMA : the journal of the American Medical Association 2006;296(14):1742-8.
2006: Daniel Menzies; Arun Nair; Brian J Lipworth
Non-invasive measurement of airway inflammation in asthma.
The Journal of asthma : official journal of the Association for the Care of Asthma 2006;43(6):407-15.
2006: Martyn L Barnes; J H Ward; Tom C Fardon; Brian J Lipworth
Effects of levocetirizine as add-on therapy to fluticasone in seasonal allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2006;36(5):676-84.
2006: Tom C Fardon; Patricia Burns; Martyn L Barnes; Brian J Lipworth
A comparison of 2 extrafine hydrofluoroalkane-134a-beclomethasone formulations on methacholine hyperresponsiveness.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2006;96(3):422-30.
2005: Martyn L Barnes; Bart T Biallosterski; Robert D Gray; Tom C Fardon; Brian J Lipworth
Decongestant effects of nasal xylometazoline and mometasone furoate in persistent allergic rhinitis.
Rhinology 2005;43(4):291-5.
2005: David G Kiely; Norman S Kennedy; Omar Pirzada; Sheila A Batchelor; Allan D Struthers; Brian J Lipworth
Elevated levels of natriuretic peptides in patients with pulmonary thromboembolism.
Respiratory medicine 2005;99(10):1286-91.
2005: Brian J Lipworth; Erika J Sims; Sudip K Das; Alyn H Morice; Brian J O'Connor
Bronchoprotection with formoterol via dry powder and metered-dose inhalers in patients with asthma.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2005;95(3):283-90.
2005: Tom C Fardon; Daniel K C Lee; Melissa R Hodge; Brian J Lipworth
Addition of fexofenadine to inhaled corticosteroid therapy to reduce inflammatory biomarkers in atopic asthma.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2005;95(3):259-65.
2005: D Menzies; Tom C Fardon; P Burns; Brian J Lipworth
Comparison of measured exhaled nitric oxide at varying flow rates.
Thorax 2005;60(9):788.
2005: Brian J Lipworth; Erika J Sims; Sudip K Das; Helen Buck; Michelle Paterson
Dose-response comparison of budesonide dry powder inhalers using adenosine monophosphate bronchial challenge.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2005;94(6):675-81.
2005: Tom C Fardon; Melissa R Hodge; Brian J Lipworth
Evaluation of an abbreviated adenosine monophosphate bronchial challenge.
Chest 2005;127(6):2222-5.
2005: Brian J Lipworth; Michael A Kaliner; Craig LaForce; James W Baker; Harold B Kaiser; Dilip Amin; Sudeep Kundu; James E Williams; Renate Engelstaetter; Donald D Banerji
Effect of ciclesonide and fluticasone on hypothalamic-pituitary-adrenal axis function in adults with mild-to-moderate persistent asthma.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2005;94(4):465-72.
2005: Daniel K C Lee; Tom C Fardon; Caroline E Bates; Kay Haggart; Lesley C McFarlane; Brian J Lipworth
Airway and systemic effects of hydrofluoroalkane formulations of high-dose ciclesonide and fluticasone in moderate persistent asthma.
Chest 2005;127(3):851-60.
2005: Brian J Lipworth
Phosphodiesterase-4 inhibitors for asthma and chronic obstructive pulmonary disease.
Lancet 2005;365(9454):167-75.
2005: Brian J Lipworth; Erika J Sims; Karla Taylor; Wendy Cockburn; Robert Fishman
Dose-response to salbutamol via a novel palm sized nebuliser (Aerodose Inhaler), conventional nebuliser (Pari LC Plus) and metered dose inhaler (Ventolin Evohaler) in moderate to severe asthmatics.
British journal of clinical pharmacology 2005;59(1):5-13.
2004: Tom C Fardon; Daniel K C Lee; Kay Haggart; Lesley C McFarlane; Brian J Lipworth
Adrenal suppression with dry powder formulations of fluticasone propionate and mometasone furoate.
American journal of respiratory and critical care medicine 2004;170(9):960-6.
2004: Tom C Fardon; Emma J Fardon; Melissa R Hodge; Brian J Lipworth
Comparative cutoff points for adenosine monophosphate and methacholine challenge testing.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2004;93(4):365-72.
2004: Tom C Fardon; Tom Fardon; Graeme Currie; Daniel K C Lee; Daniel Lee; Brian J Lipworth; Brian Lipworth
Lower thresholds for bronchial challenge testing.
Allergy 2004;59(10):1125-6.
2004: Daniel K C Lee; Caroline E Bates; Graeme P Currie; Louise M Cowan; Lesley C McFarlane; Brian J Lipworth
Effects of high-dose inhaled fluticasone propionate on the hypothalamic-pituitary-adrenal axis in asthmatic patients with severely impaired lung function.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2004;93(3):253-8.
2004: D K C Lee; Kay Haggart; Fiona M Robb; Brian J Lipworth
Montelukast protects against nasal lysine-aspirin challenge in patients with aspirin-induced asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2004;24(2):226-30.
2004: Daniel K C Lee; Kay Haggart; Brian J Lipworth
Reproducibility of response to nasal lysine-aspirin challenge in patients with aspirin-induced asthma.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2004;93(2):185-8.
2004: D K C Lee; Catherine M Jackson; Caroline E Bates; Brian J Lipworth
Cross tolerance to salbutamol occurs independently of beta2 adrenoceptor genotype-16 in asthmatic patients receiving regular formoterol or salmeterol.
Thorax 2004;59(8):662-7.
2004: Robert D Gray; Kay Haggart; Daniel K C Lee; Steven Cull; Brian J Lipworth
Effects of butterbur treatment in intermittent allergic rhinitis: a placebo-controlled evaluation.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2004;93(1):56-60.
2004: Daniel K C Lee; Robert D Gray; Andrew M Wilson; Fiona M Robb; Patricia C Soutar; Brian J Lipworth
Single and short-term dosing effects of levocetirizine on adenosine monophosphate bronchoprovocation in atopic asthma.
British journal of clinical pharmacology 2004;58(1):34-9.
2004: Daniel K C Lee; Kay Haggart; Graeme P Currie; Caroline E Bates; Brian J Lipworth
Effects of hydrofluoroalkane formulations of ciclesonide 400 microg once daily vs fluticasone 250 microg twice daily on methacholine hyper-responsiveness in mild-to-moderate persistent asthma.
British journal of clinical pharmacology 2004;58(1):26-33.
2004: Daniel K C Lee; Catherine M Jackson; Patricia C Soutar; Tom C Fardon; Brian J Lipworth
Effects of single or combined histamine H1-receptor and leukotriene CysLT1-receptor antagonism on nasal adenosine monophosphate challenge in persistent allergic rhinitis.
British journal of clinical pharmacology 2004;57(6):714-9.
2004: Tom C Fardon; Robert Gray; Brian J Lipworth
Asthma exacerbations and inhaled corticosteroids.
Lancet 2004;363(9416):1235; author reply 1235-6.
2004: D K C Lee; M Gardiner; Kay Haggart; S Fujihara; Brian J Lipworth
Comparative effects of desloratadine, fexofenadine, and levocetirizine on nasal adenosine monophosphate challenge in patients with perennial allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(4):650-3.
2004: D K C Lee; Robert D Gray; Fiona M Robb; S Fujihara; Brian J Lipworth
A placebo-controlled evaluation of butterbur and fexofenadine on objective and subjective outcomes in perennial allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(4):646-9.
2004: Daniel K C Lee; Catherine M Jackson; Kay Haggart; Brian J Lipworth
Repeated dosing effects of mediator antagonists in inhaled corticosteroid-treated atopic asthmatic patients.
Chest 2004;125(4):1372-7.
2004: Daniel K C Lee; Brian J Lipworth
The presence of emphysema does not affect the systemic bioactivity of inhaled fluticasone in severe chronic obstructive pulmonary disease.
British journal of clinical pharmacology 2004;57(4):388-92.
2004: Catherine M Jackson; Daniel K C Lee; Brian J Lipworth
The effects of butterbur on the histamine and allergen cutaneous response.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2004;92(2):250-4.
2004: Catherine M Jackson; Brian J Lipworth
Benefit-risk assessment of long-acting beta2-agonists in asthma.
Drug safety : an international journal of medical toxicology and drug experience 2004;27(4):243-70.
2004: D K C Lee; Kay Haggart; Fiona M Robb; Brian J Lipworth
Butterbur, a herbal remedy, confers complementary anti-inflammatory activity in asthmatic patients receiving inhaled corticosteroids.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(1):110-4.
2004: Daniel K C Lee; Caroline E Bates; Brian J Lipworth
Acute systemic effects of inhaled salbutamol in asthmatic subjects expressing common homozygous beta2-adrenoceptor haplotypes at positions 16 and 27.
British journal of clinical pharmacology 2004;57(1):100-4.
2004: Daniel K C Lee; Graeme P Currie; Ian P Hall; John J Lima; Brian J Lipworth
The arginine-16 beta2-adrenoceptor polymorphism predisposes to bronchoprotective subsensitivity in patients treated with formoterol and salmeterol.
British journal of clinical pharmacology 2004;57(1):68-75.
2004: Erika J Sims; Brian J Lipworth
Concomitant occasional use of salbutamol influences bronchoprotective responsiveness afforded by formoterol in patients with the glycine-16 genotype.
European journal of clinical pharmacology 2004;59(11):791-5.
2003: Daniel K C Lee; Catherine M Jackson; Graeme P Currie; Wendy Cockburn; Brian J Lipworth
Comparison of combination inhalers vs inhaled corticosteroids alone in moderate persistent asthma.
British journal of clinical pharmacology 2003;56(5):494-500.
2003: Graeme P Currie; John J Lima; JIM SYLVESTER; Daniel K C Lee; Wendy Cockburn; Brian J Lipworth
Leukotriene C4 synthase polymorphisms and responsiveness to leukotriene antagonists in asthma.
British journal of clinical pharmacology 2003;56(4):422-6.
2003: Graeme P Currie; Kay Haggart; J D Brannan; D K C Lee; Sandra D Anderson; Brian J Lipworth
Relationship between airway hyperresponsiveness to mannitol and adenosine monophosphate.
Allergy 2003;58(8):762-6.
2003: D K C Lee; I J Carstairs; Kay Haggart; Catherine M Jackson; Graeme P Currie; Brian J Lipworth
Butterbur, a herbal remedy, attenuates adenosine monophosphate induced nasal responsiveness in seasonal allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(7):882-6.
2003: Erika J Sims; Catherine M Jackson; Brian J Lipworth
Add-on therapy with montelukast or formoterol in patients with the glycine-16 beta2-receptor genotype.
British journal of clinical pharmacology 2003;56(1):104-11.
2003: Graeme P Currie; Suvi Stenback; Brian J Lipworth
Effects of fluticasone vs. fluticasone/salmeterol on airway calibre and airway hyperresponsiveness in mild persistent asthma.
British journal of clinical pharmacology 2003;56(1):11-7.
2003: Graeme P Currie; N J Syme-Grant; Lesley C McFarlane; Francis A Carey; Brian J Lipworth
Effects of low dose fluticasone/salmeterol combination on surrogate inflammatory markers in moderate persistent asthma.
Allergy 2003;58(7):602-7.
2003: Daniel K C Lee; Kay Haggart; Graeme P Currie; Sandra D Anderson; Brian J Lipworth
The effects of histamine and leukotriene receptor antagonism on nasal mannitol challenge in allergic rhinitis.
British journal of clinical pharmacology 2003;55(6):639-42.
2003: Graeme P Currie; Daniel K C Lee; Owen J Dempsey; Stephen J Fowler; Louise M Cowan; Brian J Lipworth
A proof of concept study to evaluate putative benefits of montelukast in moderate persistent asthmatics.
British journal of clinical pharmacology 2003;55(6):609-15.
2003: Graeme P Currie; Kay Haggart; D K C Lee; Stephen J Fowler; Andrew M Wilson; J D Brannan; Sandra D Anderson; Brian J Lipworth
Effects of mediator antagonism on mannitol and adenosine monophosphate challenges.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(6):783-8.
2003: Graeme P Currie; Catherine M Jackson; S A Ogston; Brian J Lipworth
Airway-stabilizing effect of long-acting beta2-agonists as add-on therapy to inhaled corticosteroids.
QJM : monthly journal of the Association of Physicians 2003;96(6):435-40.
2003: Graeme P Currie; Catherine M Jackson; Daniel K C Lee; Brian J Lipworth
Determinants of airway hyperresponsiveness in mild asthma.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2003;90(5):560-3.
2003: Robert D Gray; Brian J Lipworth
The GP's role in allergic rhinitis.
The Practitioner 2003;247(1646):418-23.
2003: Graeme P Currie; Caroline E Bates; Daniel K C Lee; Catherine M Jackson; Brian J Lipworth
Effects of fluticasone plus salmeterol versus twice the dose of fluticasone in asthmatic patients.
European journal of clinical pharmacology 2003;59(1):11-5.
2003: Graeme P Currie; Daniel K C Lee; Kay Haggart; Caroline E Bates; Brian J Lipworth
Effects of montelukast on surrogate inflammatory markers in corticosteroid-treated patients with asthma.
American journal of respiratory and critical care medicine 2003;167(9):1232-8.
2003: Andrew M Wilson; Erika J Sims; Linda C Orr; Fiona M Robb; Brian J Lipworth
An evaluation of short-term corticosteroid response in perennial allergic rhinitis using histamine and adenosine monophosphate nasal challenge.
British journal of clinical pharmacology 2003;55(4):354-9.
2003: Andrew M Wilson; Erika J Sims; Fiona M Robb; Wendy Cockburn; Brian J Lipworth
Peak inspiratory flow rate is more sensitive than acoustic rhinometry or rhinomanometry in detecting corticosteroid response with nasal histamine challenge.
Rhinology 2003;41(1):16-20.
2003: Daniel K C Lee; Fiona M Robb; Erika J Sims; Graeme P Currie; Lesley C McFarlane; Brian J Lipworth
Systemic bioactivity of intranasal triamcinolone and mometasone in perennial allergic rhinitis.
British journal of clinical pharmacology 2003;55(3):310-3.
2003: D K C Lee; Robert D Gray; Brian J Lipworth
Adenosine monophosphate bronchial provocation and the actions of asthma therapy.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(3):287-94.
2003: Andrew M Wilson; Wendy J R Coutie; Erika J Sims; Brian J Lipworth
The skin vasoconstrictor assay does not correlate significantly to airway or systemic responsiveness to inhaled budesonide in asthmatic patients.
European journal of clinical pharmacology 2003;58(10):643-7.
2003: Graeme P Currie; Stephen J Fowler; Brian J Lipworth
Dose response of inhaled corticosteroids on bronchial hyperresponsiveness: a meta-analysis.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2003;90(2):194-8.
2003: Daniel K C Lee; Caroline E Bates; Graeme P Currie; Brian J Lipworth
Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma.
The Journal of allergy and clinical immunology 2003;111(2):337-41.
2003: Linda C Orr; Stephen J Fowler; Brian J Lipworth
Relationship between changes in quality of life and measures of lung function and bronchial hyper-responsiveness during high-dose inhaled corticosteroid treatment in uncontrolled asthma.
American journal of respiratory medicine : drugs, devices, and other interventions 2003;2(5):433-8.
2003: Stephen J Fowler; Brian J Lipworth
Relationship of skin-prick reactivity to aeroallergens and hyperresponsiveness to challenges with methacholine and adenosine monophosphate.
Allergy 2003;58(1):46-52.
2002: Brian J Lipworth; Daniel K C Lee; Jacob Anhøj; Hans Bisgaard
Effect of plastic spacer handling on salbutamol lung deposition in asthmatic children.
British journal of clinical pharmacology 2002;54(5):544-7.
2002: Andrew M Wilson; Kay Haggart; Erika J Sims; Brian J Lipworth
Effects of fexofenadine and desloratadine on subjective and objective measures of nasal congestion in seasonal allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2002;32(10):1504-9.
2002: Graeme P Currie; Stephen J Fowler; Andrew M Wilson; Erika J Sims; Linda C Orr; Brian J Lipworth
Airway and systemic effects of hydrofluoroalkane fluticasone and beclomethasone in patients with asthma.
Thorax 2002;57(10):865-8.
2002: Brian J Lipworth
Antagonism of long-acting beta2-adrenoceptor agonism.
British journal of clinical pharmacology 2002;54(3):231-45.
2002: Stephen J Fowler; Linda C Orr; Erika J Sims; Andrew M Wilson; Graeme P Currie; Lesley C McFarlane; Brian J Lipworth
Therapeutic ratio of hydrofluoroalkane and chlorofluorocarbon formulations of fluticasone propionate.
Chest 2002;122(2):618-23.
2002: Owen J Dempsey; Stephen J Fowler; Andrew Wilson; Gwen Kennedy; Brian J Lipworth
Effects of adding either a leukotriene receptor antagonist or low-dose theophylline to a low or medium dose of inhaled corticosteroid in patients with persistent asthma.
Chest 2002;122(1):151-9.
2002: Graeme P Currie; Brian J Lipworth
Bronchoprotective effects of leukotriene receptor antagonists in asthma: a meta-analysis.
Chest 2002;122(1):146-50.
2002: Stephen J Fowler; Ian P Hall; Andrew M Wilson; Amanda Henry; Brian J Lipworth
5-Lipoxygenase polymorphism and in-vivo response to leukotriene receptor antagonists.
European journal of clinical pharmacology 2002;58(3):187-90.
2002: Erika J Sims; Andrew M Wilson; Paul S White; Quentin Gardiner; Brian J Lipworth
Short-term repeatability and correlates of laboratory measures of nasal function in patients with seasonal allergic rhinitis.
Rhinology 2002;40(2):66-8.
2002: Stephen J Fowler; Graeme P Currie; Brian J Lipworth
Step-down therapy with low-dose fluticasone-salmeterol combination or medium-dose hydrofluoroalkane 134a-beclomethasone alone.
The Journal of allergy and clinical immunology 2002;109(6):929-35.
2002: Brian J Lipworth; Catherine M Jackson
Second-line controller therapy for persistent asthma uncontrolled on inhaled corticosteroids: the step 3 dilemma.
Drugs 2002;62(16):2315-32.
2002: Andrew M Wilson; Linda C Orr; Wendy J R Coutie; Erika J Sims; Brian J Lipworth
A comparison of once daily fexofenadine versus the combination of montelukast plus loratadine on domiciliary nasal peak flow and symptoms in seasonal allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2002;32(1):126-32.
2002: Brian J Lipworth; G H Koppelman; Amanda Henry; Ivan R Le Jeune; Wendy J R Coutie; H Meurs; Henk Kauffman; D S Postma; Ian P Hall
Beta2 adrenoceptor promoter polymorphisms: extended haplotypes and functional effects in peripheral blood mononuclear cells.
Thorax 2002;57(1):61-6.
2002: Owen J Dempsey; Gwen Kennedy; Brian J Lipworth
Comparative efficacy and anti-inflammatory profile of once-daily therapy with leukotriene antagonist or low-dose inhaled corticosteroid in patients with mild persistent asthma.
The Journal of allergy and clinical immunology 2002;109(1):68-74.
2001: Brian J Lipworth
Emerging role of antileukotriene therapy in allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2001;31(12):1813-21.
2001: Owen J Dempsey; M Humphreys; Wendy J R Coutie; Brian J Lipworth
Relative lung delivery of fluticasone propionate via large volume spacer or nebuliser in healthy volunteers.
European journal of clinical pharmacology 2001;57(9):637-41.
2001: Andrew M Wilson; Erika J Sims; Linda C Orr; Wendy J R Coutie; Paul S White; Quentin Gardiner; Brian J Lipworth
Effects of topical corticosteroid and combined mediator blockade on domiciliary and laboratory measurements of nasal function in seasonal allergic rhinitis.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2001;87(4):344-9.
2001: Andrew M Wilson; Paul S White; Quentin Gardiner; R Nassif; Brian J Lipworth
Effects of leukotriene receptor antagonist therapy in patients with chronic rhinosinusitis in a real life rhinology clinic setting.
Rhinology 2001;39(3):142-6.
2001: Stephen J Fowler; Linda C Orr; Andrew M Wilson; Erika J Sims; Brian J Lipworth
Dose-response for adrenal suppression with hydrofluoroalkane formulations of fluticasone propionate and beclomethasone dipropionate.
British journal of clinical pharmacology 2001;52(1):93-5.
2001: Andrew M Wilson; Stephen J Fowler; S W Martin; Paul S White; Quentin Gardiner; Brian J Lipworth
Evaluation of the importance of head and probe stabilisation in acoustic rhinometry.
Rhinology 2001;39(2):93-7.
2001: Andrew M Wilson; Owen J Dempsey; Erika J Sims; Brian J Lipworth
A comparison of topical budesonide and oral montelukast in seasonal allergic rhinitis and asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2001;31(4):616-24.
2001: Stephen J Fowler; Brian J Lipworth
Pharmacokinetics and systemic beta2-adrenoceptor-mediated responses to inhaled salbutamol.
British journal of clinical pharmacology 2001;51(4):359-62.
2001: Andrew M Wilson; Owen J Dempsey; Erika J Sims; Brian J Lipworth
Evaluation of salmeterol or montelukast as second-line therapy for asthma not controlled with inhaled corticosteroids.
Chest 2001;119(4):1021-6.
2001: Stephen J Fowler; Andrew M Wilson; Ewen Griffiths; Brian J Lipworth
Comparative in vivo lung delivery of hydrofluoroalkane-salbutamol formulation via metered-dose inhaler alone, with plastic spacer, or with cardboard tube.
Chest 2001;119(4):1018-20.
2001: Andrew M Wilson; Linda C Orr; Erika J Sims; Brian J Lipworth
Effects of monotherapy with intra-nasal corticosteroid or combined oral histamine and leukotriene receptor antagonists in seasonal allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2001;31(1):61-8.
2000: I Aziz; Andrew M Wilson; Brian J Lipworth
Effects of once-daily formoterol and budesonide given alone or in combination on surrogate inflammatory markers in asthmatic adults.
Chest 2000;118(4):1049-58.
2000: Stephen J Fowler; Owen J Dempsey; Erika J Sims; Brian J Lipworth
Screening for bronchial hyperresponsiveness using methacholine and adenosine monophosphate. Relationship to asthma severity and beta(2)-receptor genotype.
American journal of respiratory and critical care medicine 2000;162(4 Pt 1):1318-22.
2000: Andrew M Wilson; Linda C Orr; Erika J Sims; Owen J Dempsey; Brian J Lipworth
Antiasthmatic effects of mediator blockade versus topical corticosteroids in allergic rhinitis and asthma.
American journal of respiratory and critical care medicine 2000;162(4 Pt 1):1297-301.
2000: Brian J Lipworth; Paul S White
Allergic inflammation in the unified airway: start with the nose.
Thorax 2000;55(10):878-81.
2000: Brian J Lipworth
The comparative safety/efficacy ratio of HFA-BDP.
Respiratory medicine 2000;94 Suppl D():S21-6.
2000: Brian J Lipworth
Targets for inhaled treatment.
Respiratory medicine 2000;94 Suppl D():S13-6.
2000: Andrew M Wilson; Owen J Dempsey; Erika J Sims; Brian J Lipworth
Subjective and objective markers of treatment response in patients with seasonal allergic rhinitis.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2000;85(2):111-4.
2000: Brian J Lipworth; Owen J Dempsey; I Aziz; Andrew M Wilson
Effects of adding a leukotriene antagonist or a long-acting beta(2)-agonist in asthmatic patients with the glycine-16 beta(2)-adrenoceptor genotype.
The American journal of medicine 2000;109(2):114-21.
2000: Brian J Lipworth; Owen J Dempsey; I Aziz
Functional antagonism with formoterol and salmeterol in asthmatic patients expressing the homozygous glycine-16 beta(2)-adrenoceptor polymorphism.
Chest 2000;118(2):321-8.
2000: Brian J Lipworth
Therapeutic implications of non-genomic glucocorticoid activity.
Lancet 2000;356(9224):87-9.
2000: AD McMahon; Brian J Lipworth; Peter G Davey; Andrew D Morris; Thomas M MacDonald
Continuity of prescribing with inhaled corticosteroids and control of asthma.
Pharmacoepidemiology and drug safety 2000;9(4):293-303.
2000: Brian J Lipworth; Catherine M Jackson
Safety of inhaled and intranasal corticosteroids: lessons for the new millennium.
Drug safety : an international journal of medical toxicology and drug experience 2000;23(1):11-33.
2000: A Wilson; Owen J Dempsey; Erika J Sims; Wendy J R Coutie; M C Paterson; Brian J Lipworth
Evaluation of treatment response in patients with seasonal allergic rhinitis using domiciliary nasal peak inspiratory flow.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2000;30(6):833-8.
2000: Owen J Dempsey; Andrew M Wilson; Erika J Sims; C Mistry; Brian J Lipworth
Additive bronchoprotective and bronchodilator effects with single doses of salmeterol and montelukast in asthmatic patients receiving inhaled corticosteroids.
Chest 2000;117(4):950-3.
2000: Andrew M Wilson; Brian J Lipworth
Dose-response evaluation of the therapeutic index for inhaled budesonide in patients with mild-to-moderate asthma.
The American journal of medicine 2000;108(4):269-75.
2000: Andrew M Wilson; A Blumsohn; Roland T Jung; Brian J Lipworth
Asthma and Cushing's syndrome.
Chest 2000;117(2):593-4.
2000: Brian J Lipworth; I Aziz
Bronchodilator response to albuterol after regular formoterol and effects of acute corticosteroid administration.
Chest 2000;117(1):156-62.
1999: Brian J Lipworth; Catherine M Jackson
Pharmacokinetics of chlorofluorocarbon and hydrofluoroalkane metered-dose inhaler formulations of beclomethasone dipropionate.
British journal of clinical pharmacology 1999;48(6):866-8.
1999: Andrew M Wilson; Erika J Sims; Linda C Orr; Brian J Lipworth
Differences in lung bioavailability between different propellants for fluticasone propionate.
Lancet 1999;354(9187):1357-8.
1999: Andrew M Wilson; Brian J Lipworth
Short-term dose-response relationships for the relative systemic effects of oral prednisolone and inhaled fluticasone in asthmatic adults.
British journal of clinical pharmacology 1999;48(4):579-85.
1999: Owen J Dempsey; Andrew M Wilson; Wendy J R Coutie; Brian J Lipworth
Evaluation of the effect of a large volume spacer on the systemic bioactivity of fluticasone propionate metered-dose inhaler.
Chest 1999;116(4):935-40.
1999: I Aziz; Lesley C McFarlane; Brian J Lipworth
Comparative trough effects of formoterol and salmeterol on lymphocyte beta2-adrenoceptor--regulation and bronchodilatation.
European journal of clinical pharmacology 1999;55(6):431-6.
1999: Owen J Dempsey; Wendy J R Coutie; Andrew M Wilson; P Williams; Brian J Lipworth
Evaluation of the buccal component of systemic absorption with inhaled fluticasone propionate.
Thorax 1999;54(7):614-7.
1999: Owen J Dempsey; A M Wilson; Brian J Lipworth
Spacer devices increase dose of inhaled corticosteroids delivered.
BMJ (Clinical research ed.) 1999;318(7200):1764.
1999: Andrew M Wilson; Owen J Dempsey; Wendy J R Coutie; Erika J Sims; Brian J Lipworth
Importance of drug-device interaction in determining systemic effects of inhaled corticosteroids.
Lancet 1999;353(9170):2128.
1999: Brian J Lipworth
Systemic adverse effects of inhaled corticosteroid therapy: A systematic review and meta-analysis.
Archives of internal medicine 1999;159(9):941-55.
1999: I Aziz; Brian J Lipworth
In vivo effect of albuterol on methacholine-contracted bronchi in conjunction with salmeterol and formoterol.
The Journal of allergy and clinical immunology 1999;103(5 Pt 1):816-22.
1999: Andrew M Wilson; E J Sims; Brian J Lipworth
Dose response with fluticasone propionate on adrenocortical activity and recovery of basal and stimulated responses after stopping treatment.
Clinical endocrinology 1999;50(3):329-35.
1999: Jacob Anhøj; Hans Bisgaard; Brian J Lipworth
Effect of electrostatic charge in plastic spacers on the lung delivery of HFA-salbutamol in children.
British journal of clinical pharmacology 1999;47(3):333-6.
1999: I Aziz; Brian J Lipworth
A bolus of inhaled budesonide rapidly reverses airway subsensitivity and beta2-adrenoceptor down-regulation after regular inhaled formoterol.
Chest 1999;115(3):623-8.
1999: Brian J Lipworth; Ian P Hall; I Aziz; KS Tan; Amanda Henry
Beta2-adrenoceptor polymorphism and bronchoprotective sensitivity with regular short- and long-acting beta2-agonist therapy.
Clinical science (London, England : 1979) 1999;96(3):253-9.
1999: Brian J Lipworth
Fortnightly review: modern drug treatment of chronic asthma.
BMJ (Clinical research ed.) 1999;318(7180):380-4.
1999: Brian J Lipworth; Ian P Hall; S Tan; I Aziz; Wendy J R Coutie
Effects of genetic polymorphism on ex vivo and in vivo function of beta2-adrenoceptors in asthmatic patients.
Chest 1999;115(2):324-8.
1999: Brian J Lipworth
Leukotriene-receptor antagonists.
Lancet 1999;353(9146):57-62.
1999: Andrew M Wilson; Brian J Lipworth
24 hour and fractionated profiles of adrenocortical activity in asthmatic patients receiving inhaled and intranasal corticosteroids.
Thorax 1999;54(1):20-6.
1999: Brian J Lipworth; I Aziz
A high dose of albuterol does not overcome bronchoprotective subsensitivity in asthmatic subjects receiving regular salmeterol or formoterol.
The Journal of allergy and clinical immunology 1999;103(1 Pt 1):88-92.
1998: Andrew M Wilson; H J Brewster; Brian J Lipworth
Dose-response comparison of systemic bioactivity with inhaled budesonide and triamcinolone acetonide in asthmatic adults.
The Journal of allergy and clinical immunology 1998;102(5):751-6.
1998: Andrew M Wilson; Erika J Sims; Lesley C McFarlane; Brian J Lipworth
Effects of intranasal corticosteroids on adrenal, bone, and blood markers of systemic activity in allergic rhinitis.
The Journal of allergy and clinical immunology 1998;102(4 Pt 1):598-604.
1998: Andrew M Wilson; Lesley C McFarlane; Brian J Lipworth
Systemic bioactivity profiles of oral prednisolone and nebulized budesonide in adult asthmatics.
Chest 1998;114(4):1022-7.
1998: Andrew M Wilson; E J Sims; Allan D Struthers; Brian J Lipworth
Inhaled corticosteroid therapy reduces the early morning peak in cortisol and aldosterone.
Clinical science (London, England : 1979) 1998;95(4):513-7.
1998: DG Kiely; AF Lee; Allan D Struthers; Brian J Lipworth
Nitric oxide: an important role in the maintenance of systemic and pulmonary vascular tone in man.
British journal of clinical pharmacology 1998;46(3):263-6.
1998: I Aziz; KS Tan; Ian P Hall; M M Devlin; Brian J Lipworth
Subsensitivity to bronchoprotection against adenosine monophosphate challenge following regular once-daily formoterol.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;12(3):580-4.
1998: I Aziz; Lesley C McFarlane; Brian J Lipworth
Concomitant inhaled corticosteroid resensitises cardiac beta2-adrenoceptors in the presence of long-acting beta2-agonist therapy.
European journal of clinical pharmacology 1998;54(5):377-81.
1998: Brian J Lipworth; S Tan; M Devlin; T Aiken; R Baker; D Hendrick
Effects of treatment with formoterol on bronchoprotection against methacholine.
The American journal of medicine 1998;104(5):431-8.
1998: Andrew M Wilson; Lesley C McFarlane; Brian J Lipworth
Effects of repeated once daily dosing of three intranasal corticosteroids on basal and dynamic measures of hypothalamic-pituitary-adrenal-axis activity.
The Journal of allergy and clinical immunology 1998;101(4 Pt 1):470-4.
1998: I Aziz; Ian P Hall; Lesley C McFarlane; Brian J Lipworth
Beta2-adrenoceptor regulation and bronchodilator sensitivity after regular treatment with formoterol in subjects with stable asthma.
The Journal of allergy and clinical immunology 1998;101(3):337-41.
1998: Andrew M Wilson; Lesley C McFarlane; Brian J Lipworth
Effects of low and high doses of inhaled flunisolide and triamcinolone acetonide on basal and dynamic measures of adrenocortical activity in healthy volunteers.
The Journal of clinical endocrinology and metabolism 1998;83(3):922-5.
1998: KS Tan; Lesley C McFarlane; Brian J Lipworth
Beta2-adrenoceptor regulation and function in female asthmatic patients receiving the oral combined contraceptive pill.
Chest 1998;113(2):278-82.
1998: Brian J Lipworth; DJ Clark
Lung delivery of non-CFC salbutamol via small volume metal spacer and large volume plastic spacer devices compared with an open vent jet nebulizer.
British journal of clinical pharmacology 1998;45(2):160-3.
1998: Andrew M Wilson; DJ Clark; M M Devlin; Lesley C McFarlane; Brian J Lipworth
Adrenocortical activity with repeated administration of one-daily inhaled fluticasone propionate and budesonide in asthmatic adults.
European journal of clinical pharmacology 1998;53(5):317-20.
1998: KS Tan; Lesley C McFarlane; Brian J Lipworth
Concomitant administration of low-dose prednisolone protects against in vivo beta2-adrenoceptor subsensitivity induced by regular formoterol.
Chest 1998;113(1):34-41.
1997: Brian J Lipworth; DJ Clark
Effects of airway calibre on lung delivery of nebulised salbutamol.
Thorax 1997;52(12):1036-9.
1997: KS Tan; Lesley C McFarlane; Brian J Lipworth
Effects of oral and inhaled corticosteroid on lymphocyte beta2-adrenoceptor function in asthmatic patients.
British journal of clinical pharmacology 1997;44(6):565-8.
1997: DJ Clark; Brian J Lipworth
Evaluation of corticotropin releasing factor stimulation and basal markers of hypothalamic-pituitary-adrenal axis suppression in asthmatic patients.
Chest 1997;112(5):1248-52.
1997: S Tan; Ian P Hall; J Dewar; Eleanor Dow; Brian J Lipworth
Association between beta 2-adrenoceptor polymorphism and susceptibility to bronchodilator desensitisation in moderately severe stable asthmatics.
Lancet 1997;350(9083):995-9.
1997: Brian J Lipworth; DJ Clark; P Koch; C Arbeeny
Pharmacokinetics and extrapulmonary beta 2 adrenoceptor activity of nebulised racemic salbutamol and its R and S isomers in healthy volunteers.
Thorax 1997;52(10):849-52.
1997: Andrew M Wilson; Lesley C McFarlane; Brian J Lipworth
Dose-response effect for adrenal suppression with repeated twice daily inhaled fluticasone propionate and triamcinolone acetonide in adult asthmatics.
American journal of respiratory and critical care medicine 1997;156(4 Pt 1):1274-7.
1997: Brian J Lipworth
Treatment of acute asthma.
Lancet 1997;350 Suppl 2():SII18-23.
1997: Brian J Lipworth; DJ Clark
Lung delivery of salbutamol given by breath activated pressurized aerosol and dry powder inhaler devices.
Pulmonary pharmacology & therapeutics 1997;10(4):211-4.
1997: Brian J Lipworth; DJ Clark; Lesley C McFarlane
Adrenocortical activity with repeated twice daily dosing of fluticasone propionate and budesonide given via a large volume spacer to asthmatic school children.
Thorax 1997;52(8):686-9.
1997: Brian J Lipworth; DJ Clark
Lung delivery of salbutamol by dry powder inhaler (Turbuhaler) and small volume antistatic metal spacer (Airomir CFC-free MDI plus NebuChamber).
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1997;10(8):1820-3.
1997: KS Tan; Lesley C McFarlane; Brian J Lipworth
Loss of normal cyclical beta 2 adrenoceptor regulation and increased premenstrual responsiveness to adenosine monophosphate in stable female asthmatic patients.
Thorax 1997;52(7):608-11.
1997: KS Tan; A Grove; A McLean; Y Gnosspelius; Ian P Hall; Brian J Lipworth
Systemic corticosteriod rapidly reverses bronchodilator subsensitivity induced by formoterol in asthmatic patients.
American journal of respiratory and critical care medicine 1997;156(1):28-35.
1997: Brian J Lipworth
Airway subsensitivity with long-acting beta 2-agonists. Is there cause for concern?
Drug safety : an international journal of medical toxicology and drug experience 1997;16(5):295-308.
1997: Brian J Lipworth; J R Seckl
Measures for detecting systemic bioactivity with inhaled and intranasal corticosteroids.
Thorax 1997;52(5):476-82.
1997: R Mathur; RA Clark; D P Dhillon; J H Winter; Brian J Lipworth
Reaudit of acute asthma admissions using a severity marker stamp and determinants of an outcome measure.
Scottish medical journal 1997;42(2):49-52.
1997: KS Tan; Lesley C McFarlane; Brian J Lipworth
Paradoxical down-regulation and desensitization of beta2-adrenoceptors by exogenous progesterone in female asthmatics.
Chest 1997;111(4):847-51.
1997: KS Tan; Lesley C McFarlane; Brian J Lipworth
Modulation of airway reactivity and peak flow variability in asthmatics receiving the oral contraceptive pill.
American journal of respiratory and critical care medicine 1997;155(4):1273-7.
1997: DG Kiely; RI Cargill; Brian J Lipworth
Effects of frusemide and hypoxia on the pulmonary vascular bed in man.
British journal of clinical pharmacology 1997;43(3):309-13.
1997: R Mathur; RA Clark; D P Dhillon; J H Winter; Brian J Lipworth
A repeat audit of hospital discharge letters in patients admitted with acute asthma.
Scottish medical journal 1997;42(1):19-21.
1997: DG Kiely; RI Cargill; Allan D Struthers; Brian J Lipworth
Cardiopulmonary effects of endothelin-1 in man.
Cardiovascular research 1997;33(2):378-86.
1997: Brian J Lipworth; DJ Clark
Comparative lung delivery of salbutamol given via Turbuhaler and Diskus dry powder inhaler devices.
European journal of clinical pharmacology 1997;53(1):47-9.
1997: Andrew M Wilson; DJ Clark; Lesley C McFarlane; Brian J Lipworth
Adrenal suppression with high doses of inhaled fluticasone propionate and triamcinolone acetonide in healthy volunteers.
European journal of clinical pharmacology 1997;53(1):33-7.
1997: KS Tan; Lesley C McFarlane; Brian J Lipworth
Effect of exogenous female sex-steroid hormones on beta 2-adrenoceptors in healthy males.
European journal of clinical pharmacology 1997;52(4):281-3.
1997: DG Kiely; RI Cargill; N M Wheeldon; Wendy J R Coutie; Brian J Lipworth
Haemodynamic and endocrine effects of type 1 angiotensin II receptor blockade in patients with hypoxaemic cor pulmonale.
Cardiovascular research 1997;33(1):201-8.
1997: Brian J Lipworth; A Grove
Evaluation of partial beta-adrenoceptor agonist activity.
British journal of clinical pharmacology 1997;43(1):9-14.
1997: DJ Clark; Brian J Lipworth
Adrenal suppression with chronic dosing of fluticasone propionate compared with budesonide in adult asthmatic patients.
Thorax 1997;52(1):55-8.
1997: DJ Clark; Brian J Lipworth
Dose-response of inhaled drugs in asthma. An update.
Clinical pharmacokinetics 1997;32(1):58-74.
1996: Brian J Lipworth
Pharmacokinetics of inhaled drugs.
British journal of clinical pharmacology 1996;42(6):697-705.
1996: R I Cargill; Brian J Lipworth
Atrial natriuretic peptide and brain natriuretic peptide in cor pulmonale. Hemodynamic and endocrine effects.
Chest 1996;110(5):1220-5.
1996: DJ Clark; Brian J Lipworth
Effect of multiple actuations, delayed inhalation and antistatic treatment on the lung bioavailability of salbutamol via a spacer device.
Thorax 1996;51(10):981-4.
1996: DJ Clark; RA Clark; Brian J Lipworth
Adrenal suppression with inhaled budesonide and fluticasone propionate given by large volume spacer to asthmatic children.
Thorax 1996;51(9):941-3.
1996: Brian J Lipworth
Clinical pharmacology of beta 3-adrenoceptors.
British journal of clinical pharmacology 1996;42(3):291-300.
1996: DG Kiely; R I Cargill; Brian J Lipworth
Angiotensin II receptor blockade and effects on pulmonary hemodynamics and hypoxic pulmonary vasoconstriction in humans.
Chest 1996;110(3):698-703.
1996: A Grove; Brian J Lipworth; P Reid; R P Smith; L Ramage; C G Ingram; R J Jenkins; J H Winter; D P Dhillon
Effects of regular salmeterol on lung function and exercise capacity in patients with chronic obstructive airways disease.
Thorax 1996;51(7):689-93.
1996: A Grove; Brian J Lipworth
Effects of prior treatment with salmeterol and formoterol on airway and systemic beta 2 responses to fenoterol.
Thorax 1996;51(6):585-9.
1996: KS Tan; Lesley C McFarlane; Wendy J R Coutie; Brian J Lipworth
Effects of exogenous female sex-steroid hormones on lymphocyte beta 2-adrenoceptors in normal females.
British journal of clinical pharmacology 1996;41(5):414-6.
1996: DG Kiely; R I Cargill; Brian J Lipworth
Effects of hypercapnia on hemodynamic, inotropic, lusitropic, and electrophysiologic indices in humans.
Chest 1996;109(5):1215-21.
1996: DJ Clark; Brian J Lipworth
Lung bioavailability of chlorofluorocarbon free, dry powder and chlorofluorocarbon containing formulations of salbutamol.
British journal of clinical pharmacology 1996;41(3):247-9.
1996: DJ Clark; J Gordon-Smith; G McPhate; G Clark; Brian J Lipworth
Lung bioavailability of generic and innovator salbutamol metered dose inhalers.
Thorax 1996;51(3):325-6.
1996: DJ Clark; A Grove; R I Cargill; Brian J Lipworth
Comparative adrenal suppression with inhaled budesonide and fluticasone propionate in adult asthmatic patients.
Thorax 1996;51(3):262-6.
1996: Brian J Lipworth
Airway and systemic effects of inhaled corticosteroids in asthma: dose response relationship.
Pulmonary pharmacology 1996;9(1):19-27.
1996: R I Cargill; Brian J Lipworth
Lisinopril attenuates acute hypoxic pulmonary vasoconstriction in humans.
Chest 1996;109(2):424-9.
1996: KS Tan; A Grove; R I Cargill; Lesley C McFarlane; Brian J Lipworth
Effects of inhaled fluticasone propionate and oral prednisolone on lymphocyte beta 2-adrenoceptor function in asthmatic patients.
Chest 1996;109(2):343-7.
1996: DJ Clark; KS Tan; Brian J Lipworth
Evaluation of plasma and urinary salbutamol levels in COPD.
European journal of clinical pharmacology 1996;51(1):91-3.
1996: R I Cargill; Lesley C McFarlane; Wendy J R Coutie; Brian J Lipworth
Acute neurohormonal responses to hypoxaemia in man.
European journal of applied physiology and occupational physiology 1996;72(3):256-60.
1996: A Grove; Lesley C McFarlane; C M Jackson; Brian J Lipworth
Effects of short-term exposure to high-dose inhaled corticosteroids on novel markers of bone metabolism.
European journal of clinical pharmacology 1996;50(4):275-7.
1996: A Grove; Brian J Lipworth
Evaluation of the beta 2 adrenoceptor agonist/antagonist activity of formoterol and salmeterol.
Thorax 1996;51(1):54-8.
1995: DG Kiely; R I Cargill; Brian J Lipworth
Acute hypoxic pulmonary vasoconstriction in man is attenuated by type I angiotensin II receptor blockade.
Cardiovascular research 1995;30(6):875-80.
1995: R I Cargill; Brian J Lipworth
Acute effects of ANP and BNP on hypoxic pulmonary vasoconstriction in humans.
British journal of clinical pharmacology 1995;40(6):585-90.
1995: R I Cargill; DG Kiely; RA Clark; Brian J Lipworth
Hypoxaemia and release of endothelin-1.
Thorax 1995;50(12):1308-10.
1995: R P Smith; Brian J Lipworth; Ian Cree; E M Spiers; J H Winter
C-reactive protein. A clinical marker in community-acquired pneumonia.
Chest 1995;108(5):1288-91.
1995: DG Kiely; R I Cargill; Brian J Lipworth
Cardiopulmonary interactions of salbutamol and hypoxaemia in healthy young volunteers.
British journal of clinical pharmacology 1995;40(4):313-8.
1995: R I Cargill; DG Kiely; Brian J Lipworth
Left ventricular systolic performance during acute hypoxemia.
Chest 1995;108(4):899-902.
1995: DG Kiely; R I Cargill; A Grove; Allan D Struthers; Brian J Lipworth
Abnormal myocardial repolarisation in response to hypoxaemia and fenoterol.
Thorax 1995;50(10):1062-6.
1995: R I Cargill; DG Kiely; Brian J Lipworth
Adverse effects of hypoxaemia on diastolic filling in humans.
Clinical science (London, England : 1979) 1995;89(2):165-9.
1995: A Grove; Brian J Lipworth
Bronchodilator subsensitivity to salbutamol after twice daily salmeterol in asthmatic patients.
Lancet 1995;346(8969):201-6.
1995: R I Cargill; Brian J Lipworth
The role of the renin-angiotensin and natriuretic peptide systems in the pulmonary vasculature.
British journal of clinical pharmacology 1995;40(1):11-8.
1995: D M Newnham; A Grove; DG McDevitt; Brian J Lipworth
Subsensitivity of bronchodilator and systemic beta 2 adrenoceptor responses after regular twice daily treatment with eformoterol dry powder in asthmatic patients.
Thorax 1995;50(5):497-504.
1995: R P Smith; Brian J Lipworth
C-reactive protein in simple community-acquired pneumonia.
Chest 1995;107(4):1028-31.
1995: A Grove; Brian J Lipworth
Tolerance with beta 2-adrenoceptor agonists: time for reappraisal.
British journal of clinical pharmacology 1995;39(2):109-18.
1995: R I Cargill; Brian J Lipworth
Pulmonary vasorelaxant activity of atrial natriuretic peptide and brain natriuretic peptide in humans.
Thorax 1995;50(2):183-5.
1995: A Grove; Lesley C McFarlane; Brian J Lipworth
Expression of the beta 2 adrenoceptor partial agonist/antagonist activity of salbutamol in states of low and high adrenergic tone.
Thorax 1995;50(2):134-8.
1995: Chim C Lang; H M McAlpine; N Kennedy; A R Rahman; Brian J Lipworth; Allan D Struthers
Effects of lisinopril on congestive heart failure in normotensive patients with diastolic dysfunction but intact systolic function.
European journal of clinical pharmacology 1995;49(1-2):15-9.
1995: R I Cargill; Allan D Struthers; Brian J Lipworth
Human C-type natriuretic peptide: effects on the haemodynamic and endocrine responses to angiotensin II.
Cardiovascular research 1995;29(1):108-11.
1995: Brian J Lipworth; D M Newnham; RA Clark; D P Dhillon; J H Winter; DG McDevitt
Comparison of the relative airways and systemic potencies of inhaled fenoterol and salbutamol in asthmatic patients.
Thorax 1995;50(1):54-61.
1995: R I Cargill; Allan D Struthers; Brian J Lipworth
Comparative effects of atrial natriuretic peptide and brain natriuretic peptide on the aldosterone and pressor responses to angiotensin II in man.
Clinical science (London, England : 1979) 1995;88(1):81-6.
1995: A Grove; Brian J Lipworth; C G Ingram; RA Clark; D P Dhillon
A comparison of the effects of prednisolone and mianserin on ventilatory, exercise and psychometric parameters in patients with chronic obstructive pulmonary disease.
European journal of clinical pharmacology 1995;48(1):13-8.
1994: A Grove; C Allam; Lesley C McFarlane; G McPhate; C M Jackson; Brian J Lipworth
A comparison of the systemic bioactivity of inhaled budesonide and fluticasone propionate in normal subjects.
British journal of clinical pharmacology 1994;38(6):527-32.
1994: R I Cargill; C S Barr; Wendy J R Coutie; Allan D Struthers; Brian J Lipworth
C-type natriuretic peptide levels in cor pulmonale and in congestive heart failure.
Thorax 1994;49(12):1247-9.
1994: R I Cargill; A C Boyter; Brian J Lipworth
Reversible myocardial ischaemia following vincristine containing chemotherapy.
Respiratory medicine 1994;88(9):709-10.
1994: R I Cargill; Brian J Lipworth
Acute effects of hypoxaemia and angiotensin II in the human pulmonary vascular bed.
Pulmonary pharmacology 1994;7(5):305-10.
1994: R I Cargill; DG Kiely; Brian J Lipworth
Hypoxaemia and the renin-angiotensin system: new answers for old questions.
Pulmonary pharmacology 1994;7(5):279-84.
1994: Brian J Lipworth; A Grove; C M Jackson
Asthma control.
Lancet 1994;344(8924):760.
1994: D M Newnham; Brian J Lipworth
Nebuliser performance, pharmacokinetics, airways and systemic effects of salbutamol given via a novel nebuliser delivery system ("Ventstream").
Thorax 1994;49(8):762-70.
1994: R I Cargill; Wendy J R Coutie; Brian J Lipworth
The effects of angiotensin II on circulating levels of natriuretic peptides.
British journal of clinical pharmacology 1994;38(2):139-42.
1994: N M Wheeldon; DG McDevitt; Brian J Lipworth
The effects of lower than conventional doses of oral nadolol on relative beta 1/beta 2-adrenoceptor blockade.
British journal of clinical pharmacology 1994;38(2):103-8.
1994: D M Newnham; DG McDevitt; Brian J Lipworth
Bronchodilator subsensitivity after chronic dosing with eformoterol in patients with asthma.
The American journal of medicine 1994;97(1):29-37.
1994: Chim C Lang; N Prasad; H M McAlpine; C Macleod; Brian J Lipworth; Thomas M MacDonald; Allan D Struthers
Increased plasma levels of brain natriuretic peptide in patients with isolated diastolic dysfunction.
American heart journal 1994;127(6):1635-6.
1994: N M Wheeldon; D M Newnham; Wendy J R Coutie; J A Peters; DG McDevitt; Brian J Lipworth
Influence of sex-steroid hormones on the regulation of lymphocyte beta 2-adrenoceptors during the menstrual cycle.
British journal of clinical pharmacology 1994;37(6):583-8.
1994: Brian J Lipworth; K D Dagg
Vasoconstrictor effects of angiotensin II on the pulmonary vascular bed.
Chest 1994;105(5):1360-4.
1994: L Ramage; Brian J Lipworth; C G Ingram; Ian Cree; D P Dhillon
Reduced protection against exercise induced bronchoconstriction after chronic dosing with salmeterol.
Respiratory medicine 1994;88(5):363-8.
1994: N M Wheeldon; DG McDevitt; Brian J Lipworth
Cardiac effects of the beta 3-adrenoceptor agonist BRL35135 in man.
British journal of clinical pharmacology 1994;37(4):363-9.
1994: Brian J Lipworth; K D Dagg
Comparative effects of angiotensin II on Doppler parameters of left and right heart systolic and diastolic blood flow.
British journal of clinical pharmacology 1994;37(3):273-8.
1994: N M Wheeldon; DG McDevitt; Lesley C McFarlane; Brian J Lipworth
Beta-adrenoceptor subtypes mediating the metabolic effects of BRL 35135 in man.
Clinical science (London, England : 1979) 1994;86(3):331-7.
1994: D M Newnham; N M Wheeldon; Lesley C McFarlane; G A Clark; DG McDevitt; Brian J Lipworth
Extrapulmonary beta 2-responses to intravenous salbutamol during the menstrual cycle.
European journal of clinical pharmacology 1994;46(6):511-5.
1993: D M Newnham; C G Ingram; A Mackie; Brian J Lipworth
Beta-adrenoceptor subtypes mediating the airways response to BRL 35135 in man.
British journal of clinical pharmacology 1993;36(6):567-71.
1993: D M Newnham; DG McDevitt; Brian J Lipworth
Comparison of the extrapulmonary beta2-adrenoceptor responses and pharmacokinetics of salbutamol given by standard metered dose-inhaler and modified actuator device.
British journal of clinical pharmacology 1993;36(5):445-50.
1993: D M Newnham; D P Dhillon; J H Winter; C M Jackson; RA Clark; Brian J Lipworth
Bronchodilator reversibility to low and high doses of terbutaline and ipratropium bromide in patients with chronic obstructive pulmonary disease.
Thorax 1993;48(11):1151-5.
1993: N M Wheeldon; DG McDevitt; Brian J Lipworth
Do beta 3-adrenoceptors mediate metabolic responses to isoprenaline.
The Quarterly journal of medicine 1993;86(9):595-600.
1993: Brian J Lipworth; J Allan; C M Jackson; P D Dhillon; J H Winter; RA Clark
An audit of hospital discharge letters in patients admitted with acute asthma. Tayside Asthma Audit Group.
Scottish medical journal 1993;38(4):116-9.
1993: D M Newnham; N M Wheeldon; Brian J Lipworth; DG McDevitt
Single dosing comparison of the relative cardiac beta 1/beta 2 activity of inhaled fenoterol and salbutamol in normal subjects.
Thorax 1993;48(6):656-8.
1993: N M Wheeldon; DG McDevitt; Brian J Lipworth
Investigation of putative cardiac beta 3-adrenoceptors in man.
The Quarterly journal of medicine 1993;86(4):255-61.
1993: D M Newnham; Wendy J R Coutie; Lesley C McFarlane; Brian J Lipworth
Comparison of parameters of in vitro lymphocyte beta 2-adrenoceptor function in normal and asthmatic subjects.
European journal of clinical pharmacology 1993;45(6):535-8.
1992: A R Rahman; DG McDevitt; Allan D Struthers; Brian J Lipworth
Sex differences in hypokalaemic and electrocardiographic effects of inhaled terbutaline.
Thorax 1992;47(12):1056-9.
1992: Chim C Lang; Wendy J R Coutie; Allan D Struthers; D P Dhillon; J H Winter; Brian J Lipworth
Elevated levels of brain natriuretic peptide in acute hypoxaemic chronic obstructive pulmonary disease.
Clinical science (London, England : 1979) 1992;83(5):529-33.
1992: N M Wheeldon; DG McDevitt; Brian J Lipworth
Selectivity of antagonist and partial agonist activity of celiprolol in normal subjects.
British journal of clinical pharmacology 1992;34(4):337-43.
1992: Brian J Lipworth; C M Jackson; D Ziyaie; J H Winter; P D Dhillon; RA Clark
An audit of acute asthma admissions to a respiratory unit.
Health bulletin 1992;50(5):389-98.
1992: A R Rahman; DG McDevitt; Allan D Struthers; Brian J Lipworth
The effects of enalapril and spironolactone on terbutaline-induced hypokalemia.
Chest 1992;102(1):91-5.
1992: N M Wheeldon; DG McDevitt; Brian J Lipworth
Evaluation of in vivo partial beta 1/beta 2-agonist activity: a dose-ranging study with carteolol.
British journal of clinical pharmacology 1992;33(4):411-6.
1992: Brian J Lipworth; DG McDevitt
Inhaled beta 2-adrenoceptor agonists in asthma: help or hindrance?
British journal of clinical pharmacology 1992;33(2):129-38.
1992: Brian J Lipworth
Risks versus benefits of inhaled beta 2-agonists in the management of asthma.
Drug safety : an international journal of medical toxicology and drug experience 1992;7(1):54-70.
1991: D M Newnham; DG McDevitt; Brian J Lipworth
The effects of frusemide and triamterene on the hypokalaemic and electrocardiographic responses to inhaled terbutaline.
British journal of clinical pharmacology 1991;32(5):630-2.
1991: J G Motwani; Brian J Lipworth
Clinical pharmacokinetics of drug administered buccally and sublingually.
Clinical pharmacokinetics 1991;21(2):83-94.
1991: Brian J Lipworth; RA Clark; DG McDevitt
Measurement of normal human airways response to beta-adrenoceptor stimulation using a forced oscillation technique.
Journal of clinical pharmacy and therapeutics 1991;16(3):187-91.
1991: N M Wheeldon; D M Newnham; G C Fraser; DG McDevitt; Brian J Lipworth
The effect of pindolol on creatine kinase is not due to beta 2-adrenoceptor partial agonist activity.
British journal of clinical pharmacology 1991;31(6):723-4.
1991: Brian J Lipworth; N A Irvine; DG McDevitt
The effects of time and dose on the relative beta 1- and beta 2-adrenoceptor antagonism of betaxolol and atenolol.
British journal of clinical pharmacology 1991;31(2):154-9.
1991: Brian J Lipworth; B F Tregaskis; DG McDevitt
Comparison of hypokalaemic, electrocardiographic and haemodynamic responses to inhaled isoprenaline and salbutamol in young and elderly subjects.
European journal of clinical pharmacology 1991;40(3):255-60.
1991: Brian J Lipworth; N A Irvine; DG McDevitt
A dose-ranging study to evaluate the beta 1-adrenoceptor selectivity of bisoprolol.
European journal of clinical pharmacology 1991;40(2):135-9.
1991: Brian J Lipworth; N A Irvine; DG McDevitt
The effects of chronic dosing on the beta 1 and beta 2-adrenoceptor antagonism of betaxolol and atenolol.
European journal of clinical pharmacology 1991;40(5):467-71.
1990: Brian J Lipworth; DG McDevitt; Allan D Struthers
Hypokalemic and ECG sequelae of combined beta-agonist/diuretic therapy. Protection by conventional doses of spironolactone but not triamterene.
Chest 1990;98(4):811-5.
1990: Brian J Lipworth; RA Clark; D P Dhillon; DG McDevitt
Comparison of the effects of prolonged treatment with low and high doses of inhaled terbutaline on beta-adrenoceptor responsiveness in patients with chronic obstructive pulmonary disease.
The American review of respiratory disease 1990;142(2):338-42.
1990: N A Irvine; Brian J Lipworth; DG McDevitt
A dose-ranging study to evaluate the beta-adrenoceptor selectivity of single doses of betaxolol.
British journal of clinical pharmacology 1990;30(1):119-26.
1990: Brian J Lipworth; DG McDevitt; Allan D Struthers
Electrocardiographic changes induced by inhaled salbutamol after treatment with bendrofluazide: effects of replacement therapy with potassium, magnesium and triamterene.
Clinical science (London, England : 1979) 1990;78(3):255-9.
1990: Brian J Lipworth; RA Clark; D P Dhillon; J B Palmer; DG McDevitt
Comparison of the efficacy and systemic effects of 4 mg and 8 mg formulations of salbutamol controlled release in patients with asthma.
European journal of clinical pharmacology 1990;39(3):281-5.
1990: Brian J Lipworth; RA Clark; D P Dhillon; DG McDevitt
Subsensitivity of beta-adrenoceptor responses in asthmatic patients taking regular low dose inhaled salbutamol.
European journal of clinical pharmacology 1990;38(2):203-5.
1989: Brian J Lipworth; B F Tregaskis; DG McDevitt
Beta-adrenoceptor responses to inhaled salbutamol in the elderly.
British journal of clinical pharmacology 1989;28(6):725-9.
1989: Brian J Lipworth; Allan D Struthers; DG McDevitt
Tachyphylaxis to systemic but not to airway responses during prolonged therapy with high dose inhaled salbutamol in asthmatics.
The American review of respiratory disease 1989;140(3):586-92.
1989: Brian J Lipworth; R A Brown; DG McDevitt
Assessment of airways, tremor and chronotropic responses to inhaled salbutamol in the quantification of beta 2-adrenoceptor blockade.
British journal of clinical pharmacology 1989;28(1):95-102.
1989: Brian J Lipworth; DG McDevitt; Allan D Struthers
Prior treatment with diuretic augments the hypokalemic and electrocardiographic effects of inhaled albuterol.
The American journal of medicine 1989;86(6 Pt 1):653-7.
1989: Brian J Lipworth; john mcmurray; R A Clark; Allan D Struthers
Development of persistent late onset asthma following treatment with captopril.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1989;2(6):586-8.
1989: Brian J Lipworth; DG McDevitt; Allan D Struthers
Systemic beta-adrenoceptor responses to salbutamol given by metered-dose inhaler alone and with pear shaped spacer attachment: comparison of electrocardiographic, hypokalaemic and haemodynamic effects.
British journal of clinical pharmacology 1989;27(6):837-42.
1989: Brian J Lipworth; RA Clark; C G Fraser; DG McDevitt
The biochemical effects of high-dose inhaled salbutamol in patients with asthma.
European journal of clinical pharmacology 1989;36(4):357-60.
1989: Brian J Lipworth; RA Clark; D P Dhillon; T A Moreland; Allan D Struthers; G A Clark; DG McDevitt
Pharmacokinetics, efficacy and adverse effects of sublingual salbutamol in patients with asthma.
European journal of clinical pharmacology 1989;37(6):567-71.
1989: Brian J Lipworth; RA Clark; D P Dhillon; M K Charter; J B Palmer; DG McDevitt
Single dose and steady-state pharmacokinetics of 4 mg and 8 mg oral salbutamol controlled-release in patients with bronchial asthma.
European journal of clinical pharmacology 1989;37(1):49-52.
1989: Brian J Lipworth; Lesley C McFarlane; Wendy J R Coutie; DG McDevitt
Evaluation of the metabolic responses to inhaled salbutamol in the measurement of beta 2-adrenoceptor blockade.
European journal of clinical pharmacology 1989;37(3):297-300.
1989: Brian J Lipworth; DG McDevitt
Beta-adrenoceptor responses to inhaled salbutamol in normal subjects.
European journal of clinical pharmacology 1989;36(3):239-45.
1988: Brian J Lipworth; RA Clark; D P Dhillon; R A Brown; DG McDevitt
Beta-adrenoceptor responses to high doses of inhaled salbutamol in patients with bronchial asthma.
British journal of clinical pharmacology 1988;26(5):527-33.