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Brian Lipworth

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Disorders

Asthma

Procedures

Chemicals & Drugs

Concepts & Ideas

Drug Dose-Response Relationship

Phenomena

Forced Expiratory Volume

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Network (preview)

Co-Publications
Name
43
Wilson, Andrew
41
McDevitt, DG
40
McFarlane, Lesley
27
Sims, Erika
27
Lee, Daniel
23
Currie, Graeme
20
Struthers, Allan
19
Coutie, Wendy
18
Clark, DJ
18
Fardon, Tom
17
Haggart, Kay
17
Clark, RA
17
Dempsey, Owen
15
Fowler, Stephen
14
Jackson, Catherine

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Publications

TOP 3
Lipworth Brian J; Williamson Peter A
Think the impossible: beta-blockers for treating asthma.
Nair Arun; Clearie Karine; Menzies Daniel; Meldrum Karen; McFarlane Lesley; Lipworth Brian J
A novel breath-actuated integrated vortex spacer device increases relative lung bioavailability of fluticasone/salmeterol in combination.
Williamson P A; Clearie K; Vaidyanathan S; Lipworth B
Effects of methacholine challenge on alveolar nitric oxide.

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All Publications

2010: Lipworth Brian J; Williamson Peter A
Think the impossible: beta-blockers for treating asthma.
Clinical science (London, England : 1979) 2010;118(2):115-20.
2009: Nair Arun; Clearie Karine; Menzies Daniel; Meldrum Karen; McFarlane Lesley; Lipworth Brian J
A novel breath-actuated integrated vortex spacer device increases relative lung bioavailability of fluticasone/salmeterol in combination.
Pulmonary pharmacology & therapeutics 2009;22(4):305-10.
2009: Williamson P A; Clearie K; Vaidyanathan S; Lipworth B
Effects of methacholine challenge on alveolar nitric oxide.
Thorax 2009;64(6):549-50.
2009: Vaidyanathan S; Nair A; Barnes M L; Meldrum K; Lipworth B J
Effect of levocetirizine on nasal provocation testing with adenosine monophosphate compared with allergen challenge in allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(3):409-16.
2009: Williamson Peter A; Menzies Daniel; Nair Arun; Tutuncu Ahmet; Lipworth Brian J
A proof-of-concept study to evaluate the antiinflammatory effects of a novel soluble cyclodextrin formulation of nebulized budesonide in patients with mild to moderate asthma.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2009;102(2):161-7.
2009: Nair Arun; Menzies Daniel; Hopkinson Pippa; McFarlane Lesley; Lipworth Brian J
In vivo comparison of the relative systemic bioavailability of fluticasone propionate from three anti-static spacers and a metered dose inhaler.
British journal of clinical pharmacology 2009;67(2):191-8.
2009: Vaidyanathan Sriram; Barnes Martyn; Lipworth Brian J
Comparative safety and efficacy of 2 formulations of fluticasone aqueous nasal spray in persistent allergic rhinitis.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2009;102(1):76-83.
2009: Lipworth Brian J; Williamson Peter A
Beta blockers for asthma: a double-edged sword.
Lancet 2009;373(9658):104-5.
2008: Menzies Daniel; Jackson Cathy; Mistry Catrina; Houston Ruth; Lipworth Brian J
Symptoms, spirometry, exhaled nitric oxide, and asthma exacerbations in clinical practice.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2008;101(3):248-55.
2008: Basu K; Palmer C N A; Lipworth B J; Irwin McLean W H; Terron-Kwiatkowski A; Zhao Y; Liao H; Smith F J D; Mitra A; Mukhopadhyay S
Filaggrin null mutations are associated with increased asthma exacerbations in children and young adults.
Allergy 2008;63(9):1211-7.
2008: Nair Arun; Menzies Daniel; Barnes Martyn; Burns Patricia; McFarlane Lesley; Lipworth Brian J
Respirable dose delivery of fluticasone propionate from a small valved holding chamber, a compact breath actuated integrated vortex device and a metered dose inhaler.
British journal of clinical pharmacology 2008;66(1):20-6.
2008: Menzies Daniel; Nair Arun; Meldrum Karen T; Hopkinson Pippa; Lipworth Brian J
Effect of aspirin on airway inflammation and pulmonary function in patients with persistent asthma.
The Journal of allergy and clinical immunology 2008;121(5):1184-1189.e4.
2007: Tayab Zia R; Fardon Tom C; Lee Daniel K C; Haggart Kay; McFarlane Lesley C; Lipworth Brian J; Hochhaus Günther
Pharmacokinetic/pharmacodynamic evaluation of urinary cortisol suppression after inhalation of fluticasone propionate and mometasone furoate.
British journal of clinical pharmacology 2007;64(5):698-705.
2007: Barnes Martyn L; Lipworth Brian J
Removing nasal valve obstruction in peak nasal inspiratory flow measurement.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2007;99(1):59-60.
2007: Menzies D; Nair A; Hopkinson P; McFarlane L; Lipworth B J
Differential anti-inflammatory effects of large and small particle size inhaled corticosteroids in asthma.
Allergy 2007;62(6):661-7.
2007: Lipworth Brian J
Long-acting beta2-adrenoceptor agonists: a smart choice for asthma?
Trends in pharmacological sciences 2007;28(6):257-62.
2007: Fardon Tom; Haggart Kay; Lee Daniel K C; Lipworth Brian J
A proof of concept study to evaluate stepping down the dose of fluticasone in combination with salmeterol and tiotropium in severe persistent asthma.
Respiratory medicine 2007;101(6):1218-28.
2007: Menzies Daniel; Nair Arun; Fardon Tom; Barnes Martyn; Burns Patricia; Lipworth Brian
An in vivo and in vitro comparison of inhaled steroid delivery via a novel vortex actuator and a conventional valved holding chamber.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2007;98(5):471-9.
2007: Barnes M L; Menzies D; Nair A R; Hopkinson P J; Lipworth B J
A proof-of-concept study to assess the putative dose response to topical corticosteroid in persistent allergic rhinitis using adenosine monophosphate challenge.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2007;37(5):696-703.
2007: Menzies Daniel; Nair Arun; Meldrum Karen T; Fleming Dawn; Barnes Martyn; Lipworth Brian J
Simvastatin does not exhibit therapeutic anti-inflammatory effects in asthma.
The Journal of allergy and clinical immunology 2007;119(2):328-35.
2007: Barnes M L; Menzies D; Fardon T C; Burns P; Wilson A M; Lipworth B J
Combined mediator blockade or topical steroid for treating the unified allergic airway.
Allergy 2007;62(1):73-80.
2006: Barnes M L; Biallosterski B T; Fujihara S; Gray R D; Fardon T C; Lipworth B J
Effects of intranasal corticosteroid on nasal adenosine monophosphate challenge in persistent allergic rhinitis.
Allergy 2006;61(11):1319-25.
2006: Palmer C N A; Lipworth B J; Lee S; Ismail T; Macgregor D F; Mukhopadhyay S
Arginine-16 beta2 adrenoceptor genotype predisposes to exacerbations in young asthmatics taking regular salmeterol.
Thorax 2006;61(11):940-4.
2006: Menzies Daniel; Nair Arun; Williamson Peter A; Schembri Stuart; Al-Khairalla Mudher Z H; Barnes Martyn; Fardon Tom C; McFarlane Lesley; Magee Gareth J; Lipworth Brian J
Respiratory symptoms, pulmonary function, and markers of inflammation among bar workers before and after a legislative ban on smoking in public places.
JAMA : the journal of the American Medical Association 2006;296(14):1742-8.
2006: Menzies Daniel; Nair Arun; Lipworth Brian J
Non-invasive measurement of airway inflammation in asthma.
The Journal of asthma : official journal of the Association for the Care of Asthma 2006;43(6):407-15.
2006: Barnes M L; Ward J H; Fardon T C; Lipworth B J
Effects of levocetirizine as add-on therapy to fluticasone in seasonal allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2006;36(5):676-84.
2006: Fardon Tom C; Burns Patricia; Barnes Martyn L; Lipworth Brian J
A comparison of 2 extrafine hydrofluoroalkane-134a-beclomethasone formulations on methacholine hyperresponsiveness.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2006;96(3):422-30.
2005: Barnes Martyn L; Biallosterski Bart T; Gray Robert D; Fardon Tom C; Lipworth Brian J
Decongestant effects of nasal xylometazoline and mometasone furoate in persistent allergic rhinitis.
Rhinology 2005;43(4):291-5.
2005: Kiely David G; Kennedy Norman S; Pirzada Omar; Batchelor Sheila A; Struthers Allan D; Lipworth Brian J
Elevated levels of natriuretic peptides in patients with pulmonary thromboembolism.
Respiratory medicine 2005;99(10):1286-91.
2005: Lipworth Brian J; Sims Erica J; Das Sudip K; Morice Alyn H; O'Connor Brian J
Bronchoprotection with formoterol via dry powder and metered-dose inhalers in patients with asthma.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2005;95(3):283-90.
2005: Fardon Tom C; Lee Daniel K C; Hodge Melissa R; Lipworth Brian J
Addition of fexofenadine to inhaled corticosteroid therapy to reduce inflammatory biomarkers in atopic asthma.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2005;95(3):259-65.
2005: Menzies D; Fardon T; Burns P; Lipworth B J
Comparison of measured exhaled nitric oxide at varying flow rates.
Thorax 2005;60(9):788.
2005: Lipworth Brian J; Sims Erika J; Das Sudip K; Buck Helen; Paterson Michelle
Dose-response comparison of budesonide dry powder inhalers using adenosine monophosphate bronchial challenge.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2005;94(6):675-81.
2005: Fardon Tom C; Hodge Melissa R; Lipworth Brian J
Evaluation of an abbreviated adenosine monophosphate bronchial challenge.
Chest 2005;127(6):2222-5.
2005: Lipworth Brian J; Kaliner Michael A; LaForce Craig F; Baker James W; Kaiser Harold B; Amin Dilip; Kundu Sudeep; Williams James E; Engelstaetter Renate; Banerji Donald D
Effect of ciclesonide and fluticasone on hypothalamic-pituitary-adrenal axis function in adults with mild-to-moderate persistent asthma.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2005;94(4):465-72.
2005: Lee Daniel K C; Fardon Thomas C; Bates Caroline E; Haggart Kay; McFarlane Lesley C; Lipworth Brian J
Airway and systemic effects of hydrofluoroalkane formulations of high-dose ciclesonide and fluticasone in moderate persistent asthma.
Chest 2005;127(3):851-60.
2005: Lipworth Brian J
Phosphodiesterase-4 inhibitors for asthma and chronic obstructive pulmonary disease.
Lancet 2005;365(9454):167-75.
2005: Lipworth Brian J; Sims Erika J; Taylor Karla; Cockburn Wendy; Fishman Robert
Dose-response to salbutamol via a novel palm sized nebuliser (Aerodose Inhaler), conventional nebuliser (Pari LC Plus) and metered dose inhaler (Ventolin Evohaler) in moderate to severe asthmatics.
British journal of clinical pharmacology 2005;59(1):5-13.
2004: Fardon Tom C; Lee Daniel K C; Haggart Kay; McFarlane Lesley C; Lipworth Brian J
Adrenal suppression with dry powder formulations of fluticasone propionate and mometasone furoate.
American journal of respiratory and critical care medicine 2004;170(9):960-6.
2004: Fardon Tom C; Fardon Emma J; Hodge Melissa R; Lipworth Brian J
Comparative cutoff points for adenosine monophosphate and methacholine challenge testing.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2004;93(4):365-72.
2004: Fardon Tom C; Currie Graeme; Lee Daniel K C; Lipworth Brian J;
Lower thresholds for bronchial challenge testing.
Allergy 2004;59(10):1125-6.
2004: Lee Daniel K C; Bates Caroline E; Currie Graeme P; Cowan Louise M; McFarlane Lesley C; Lipworth Brian J
Effects of high-dose inhaled fluticasone propionate on the hypothalamic-pituitary-adrenal axis in asthmatic patients with severely impaired lung function.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2004;93(3):253-8.
2004: Lee D K C; Haggart K; Robb F M; Lipworth B J
Montelukast protects against nasal lysine-aspirin challenge in patients with aspirin-induced asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2004;24(2):226-30.
2004: Lee Daniel K C; Haggart Kay; Lipworth Brian J
Reproducibility of response to nasal lysine-aspirin challenge in patients with aspirin-induced asthma.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2004;93(2):185-8.
2004: Lee D K C; Jackson C M; Bates C E; Lipworth B J
Cross tolerance to salbutamol occurs independently of beta2 adrenoceptor genotype-16 in asthmatic patients receiving regular formoterol or salmeterol.
Thorax 2004;59(8):662-7.
2004: Gray Robert D; Haggart Kay; Lee Daniel K C; Cull Steven; Lipworth Brian J
Effects of butterbur treatment in intermittent allergic rhinitis: a placebo-controlled evaluation.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2004;93(1):56-60.
2004: Lee Daniel K C; Gray Robert D; Wilson Andrew M; Robb Fiona M; Soutar Patricia C; Lipworth Brian J
Single and short-term dosing effects of levocetirizine on adenosine monophosphate bronchoprovocation in atopic asthma.
British journal of clinical pharmacology 2004;58(1):34-9.
2004: Lee Daniel K C; Haggart Kay; Currie Graeme P; Bates Caroline E; Lipworth Brian J
Effects of hydrofluoroalkane formulations of ciclesonide 400 microg once daily vs fluticasone 250 microg twice daily on methacholine hyper-responsiveness in mild-to-moderate persistent asthma.
British journal of clinical pharmacology 2004;58(1):26-33.
2004: Lee Daniel K C; Jackson Catherine M; Soutar Patricia C; Fardon Thomas C; Lipworth Brian J
Effects of single or combined histamine H1-receptor and leukotriene CysLT1-receptor antagonism on nasal adenosine monophosphate challenge in persistent allergic rhinitis.
British journal of clinical pharmacology 2004;57(6):714-9.
2004: Fardon Tom; Gray Robert; Lipworth Brian
Asthma exacerbations and inhaled corticosteroids.
Lancet 2004;363(9416):1235; author reply 1235-6.
2004: Lee D K C; Gardiner M; Haggart K; Fujihara S; Lipworth B J
Comparative effects of desloratadine, fexofenadine, and levocetirizine on nasal adenosine monophosphate challenge in patients with perennial allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(4):650-3.
2004: Lee D K C; Gray R D; Robb F M; Fujihara S; Lipworth B J
A placebo-controlled evaluation of butterbur and fexofenadine on objective and subjective outcomes in perennial allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(4):646-9.
2004: Lee Daniel K C; Jackson Catherine M; Haggart Kay; Lipworth Brian J
Repeated dosing effects of mediator antagonists in inhaled corticosteroid-treated atopic asthmatic patients.
Chest 2004;125(4):1372-7.
2004: Lee Daniel K C; Lipworth Brian J
The presence of emphysema does not affect the systemic bioactivity of inhaled fluticasone in severe chronic obstructive pulmonary disease.
British journal of clinical pharmacology 2004;57(4):388-92.
2004: Jackson Catherine M; Lee Daniel K C; Lipworth Brian J
The effects of butterbur on the histamine and allergen cutaneous response.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2004;92(2):250-4.
2004: Lee D K C; Haggart K; Robb F M; Lipworth B J
Butterbur, a herbal remedy, confers complementary anti-inflammatory activity in asthmatic patients receiving inhaled corticosteroids.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(1):110-4.
2004: Lee Daniel K C; Bates Caroline E; Lipworth Brian J
Acute systemic effects of inhaled salbutamol in asthmatic subjects expressing common homozygous beta2-adrenoceptor haplotypes at positions 16 and 27.
British journal of clinical pharmacology 2004;57(1):100-4.
2004: Lee Daniel K C; Currie Graeme P; Hall Ian P; Lima John J; Lipworth Brian J
The arginine-16 beta2-adrenoceptor polymorphism predisposes to bronchoprotective subsensitivity in patients treated with formoterol and salmeterol.
British journal of clinical pharmacology 2004;57(1):68-75.
2004: Sims Erika J; Lipworth Brian J
Concomitant occasional use of salbutamol influences bronchoprotective responsiveness afforded by formoterol in patients with the glycine-16 genotype.
European journal of clinical pharmacology 2004;59(11):791-5.
2004: Jackson Catherine M; Lipworth Brian
Benefit-risk assessment of long-acting beta2-agonists in asthma.
Drug safety : an international journal of medical toxicology and drug experience 2004;27(4):243-70.
2003: Lee Daniel K C; Jackson Catherine M; Currie Graeme P; Cockburn Wendy J; Lipworth Brian J
Comparison of combination inhalers vs inhaled corticosteroids alone in moderate persistent asthma.
British journal of clinical pharmacology 2003;56(5):494-500.
2003: Currie Graeme P; Lima John J; Sylvester Jim E; Lee Daniel K C; Cockburn Wendy J R; Lipworth Brian J
Leukotriene C4 synthase polymorphisms and responsiveness to leukotriene antagonists in asthma.
British journal of clinical pharmacology 2003;56(4):422-6.
2003: Currie G P; Haggart K; Brannan J D; Lee D K C; Anderson S D; Lipworth B J
Relationship between airway hyperresponsiveness to mannitol and adenosine monophosphate.
Allergy 2003;58(8):762-6.
2003: Lee D K C; Carstairs I J; Haggart K; Jackson C M; Currie G P; Lipworth B J
Butterbur, a herbal remedy, attenuates adenosine monophosphate induced nasal responsiveness in seasonal allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(7):882-6.
2003: Sims Erika J; Jackson Catherine M; Lipworth Brian J
Add-on therapy with montelukast or formoterol in patients with the glycine-16 beta2-receptor genotype.
British journal of clinical pharmacology 2003;56(1):104-11.
2003: Currie Graeme P; Stenback Suvi; Lipworth Brian J
Effects of fluticasone vs. fluticasone/salmeterol on airway calibre and airway hyperresponsiveness in mild persistent asthma.
British journal of clinical pharmacology 2003;56(1):11-7.
2003: Currie G P; Syme-Grant N J; McFarlane L C; Carey F A; Lipworth B J
Effects of low dose fluticasone/salmeterol combination on surrogate inflammatory markers in moderate persistent asthma.
Allergy 2003;58(7):602-7.
2003: Lee Daniel K C; Haggart Kay; Currie Graeme P; Anderson Sandra D; Lipworth Brian J
The effects of histamine and leukotriene receptor antagonism on nasal mannitol challenge in allergic rhinitis.
British journal of clinical pharmacology 2003;55(6):639-42.
2003: Currie Graeme P; Lee Daniel K C; Dempsey Owen J; Fowler Stephen J; Cowan Louise M; Lipworth Brian J
A proof of concept study to evaluate putative benefits of montelukast in moderate persistent asthmatics.
British journal of clinical pharmacology 2003;55(6):609-15.
2003: Currie G P; Haggart K; Lee D K C; Fowler S J; Wilson A M; Brannan J D; Anderson S D; Lipworth B J
Effects of mediator antagonism on mannitol and adenosine monophosphate challenges.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(6):783-8.
2003: Currie G P; Jackson C M; Ogston S A; Lipworth B J
Airway-stabilizing effect of long-acting beta2-agonists as add-on therapy to inhaled corticosteroids.
QJM : monthly journal of the Association of Physicians 2003;96(6):435-40.
2003: Currie Graeme P; Jackson Catherine M; Lee Daniel K C; Lipworth Brian J
Determinants of airway hyperresponsiveness in mild asthma.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2003;90(5):560-3.
2003: Gray Robert D; Lipworth Brian J
The GP's role in allergic rhinitis.
The Practitioner 2003;247(1646):418-23.
2003: Currie Graeme P; Bates Caroline E; Lee Daniel K C; Jackson Catherine M; Lipworth Brian J
Effects of fluticasone plus salmeterol versus twice the dose of fluticasone in asthmatic patients.
European journal of clinical pharmacology 2003;59(1):11-5.
2003: Currie Graeme P; Lee Daniel K C; Haggart Kay; Bates Caroline E; Lipworth Brian J
Effects of montelukast on surrogate inflammatory markers in corticosteroid-treated patients with asthma.
American journal of respiratory and critical care medicine 2003;167(9):1232-8.
2003: Wilson Andrew M; Sims Erika J; Orr Linda C; Robb Fiona; Lipworth Brian J
An evaluation of short-term corticosteroid response in perennial allergic rhinitis using histamine and adenosine monophosphate nasal challenge.
British journal of clinical pharmacology 2003;55(4):354-9.
2003: Wilson Andrew M; Sims Erika J; Robb Fiona; Cockburn Wendy; Lipworth Brian J
Peak inspiratory flow rate is more sensitive than acoustic rhinometry or rhinomanometry in detecting corticosteroid response with nasal histamine challenge.
Rhinology 2003;41(1):16-20.
2003: Lee Daniel K C; Robb Fiona M; Sims Erika J; Currie Graeme P; McFarlane Lesley C; Lipworth Brian J
Systemic bioactivity of intranasal triamcinolone and mometasone in perennial allergic rhinitis.
British journal of clinical pharmacology 2003;55(3):310-3.
2003: Lee D K C; Gray R D; Lipworth B J
Adenosine monophosphate bronchial provocation and the actions of asthma therapy.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(3):287-94.
2003: Wilson Andrew M; Coutie Wendy J R; Sims Erika J; Lipworth Brian J
The skin vasoconstrictor assay does not correlate significantly to airway or systemic responsiveness to inhaled budesonide in asthmatic patients.
European journal of clinical pharmacology 2003;58(10):643-7.
2003: Currie Graeme P; Fowler Stephen J; Lipworth Brian J
Dose response of inhaled corticosteroids on bronchial hyperresponsiveness: a meta-analysis.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2003;90(2):194-8.
2003: Lee Daniel K C; Bates Caroline E; Currie Graeme P; Lipworth Brian J
Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma.
The Journal of allergy and clinical immunology 2003;111(2):337-41.
2003: Fowler Stephen J; Lipworth Brian J
Relationship of skin-prick reactivity to aeroallergens and hyperresponsiveness to challenges with methacholine and adenosine monophosphate.
Allergy 2003;58(1):46-52.
2003: Orr Linda C; Fowler Stephen J; Lipworth Brian J
Relationship between changes in quality of life and measures of lung function and bronchial hyper-responsiveness during high-dose inhaled corticosteroid treatment in uncontrolled asthma.
American journal of respiratory medicine : drugs, devices, and other interventions 2003;2(5):433-8.
2002: Lipworth Brian J; Lee Daniel K C; Anhøj Jacob; Bisgaard Hans
Effect of plastic spacer handling on salbutamol lung deposition in asthmatic children.
British journal of clinical pharmacology 2002;54(5):544-7.
2002: Wilson A M; Haggart K; Sims E J; Lipworth B J
Effects of fexofenadine and desloratadine on subjective and objective measures of nasal congestion in seasonal allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2002;32(10):1504-9.
2002: Currie G P; Fowler S J; Wilson A M; Sims E J; Orr L C; Lipworth B J
Airway and systemic effects of hydrofluoroalkane fluticasone and beclomethasone in patients with asthma.
Thorax 2002;57(10):865-8.
2002: Lipworth Brian J
Antagonism of long-acting beta2-adrenoceptor agonism.
British journal of clinical pharmacology 2002;54(3):231-45.
2002: Fowler Stephen J; Orr Linda C; Sims Erika J; Wilson Andrew M; Currie Graeme P; McFarlane Lesley; Lipworth Brian J
Therapeutic ratio of hydrofluoroalkane and chlorofluorocarbon formulations of fluticasone propionate.
Chest 2002;122(2):618-23.
2002: Dempsey Owen J; Fowler Stephen J; Wilson Andrew; Kennedy Gwen; Lipworth Brian J
Effects of adding either a leukotriene receptor antagonist or low-dose theophylline to a low or medium dose of inhaled corticosteroid in patients with persistent asthma.
Chest 2002;122(1):151-9.
2002: Currie Graeme P; Lipworth Brian J
Bronchoprotective effects of leukotriene receptor antagonists in asthma: a meta-analysis.
Chest 2002;122(1):146-50.
2002: Fowler Stephen J; Hall Ian P; Wilson Andrew M; Wheatley Amanda P; Lipworth Brian J
5-Lipoxygenase polymorphism and in-vivo response to leukotriene receptor antagonists.
European journal of clinical pharmacology 2002;58(3):187-90.
2002: Sims Erika J; Wilson Andrew M; White Paul S; Gardiner Quentin; Lipworth Brian J
Short-term repeatability and correlates of laboratory measures of nasal function in patients with seasonal allergic rhinitis.
Rhinology 2002;40(2):66-8.
2002: Fowler Stephen J; Currie Graeme P; Lipworth Brian J
Step-down therapy with low-dose fluticasone-salmeterol combination or medium-dose hydrofluoroalkane 134a-beclomethasone alone.
The Journal of allergy and clinical immunology 2002;109(6):929-35.
2002: Wilson A M; Orr L C; Coutie W J R; Sims E J; Lipworth B J
A comparison of once daily fexofenadine versus the combination of montelukast plus loratadine on domiciliary nasal peak flow and symptoms in seasonal allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2002;32(1):126-32.
2002: Lipworth B; Koppelman G H; Wheatley A P; Le Jeune I; Coutie W; Meurs H; Kauffman H F; Postma D S; Hall I P
Beta2 adrenoceptor promoter polymorphisms: extended haplotypes and functional effects in peripheral blood mononuclear cells.
Thorax 2002;57(1):61-6.
2002: Dempsey Owen J; Kennedy Gwen; Lipworth Brian J
Comparative efficacy and anti-inflammatory profile of once-daily therapy with leukotriene antagonist or low-dose inhaled corticosteroid in patients with mild persistent asthma.
The Journal of allergy and clinical immunology 2002;109(1):68-74.
2002: Lipworth Brian J; Jackson Catherine M
Second-line controller therapy for persistent asthma uncontrolled on inhaled corticosteroids: the step 3 dilemma.
Drugs 2002;62(16):2315-32.
2001: Lipworth B J
Emerging role of antileukotriene therapy in allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2001;31(12):1813-21.
2001: Dempsey O J; Humphreys M; Coutie W J; Lipworth B J
Relative lung delivery of fluticasone propionate via large volume spacer or nebuliser in healthy volunteers.
European journal of clinical pharmacology 2001;57(9):637-41.
2001: Wilson A M; Sims E J; Orr L C; Coutie W J; White P S; Gardiner Q; Lipworth B J
Effects of topical corticosteroid and combined mediator blockade on domiciliary and laboratory measurements of nasal function in seasonal allergic rhinitis.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2001;87(4):344-9.
2001: Wilson A M; White P S; Gardiner Q; Nassif R; Lipworth B J
Effects of leukotriene receptor antagonist therapy in patients with chronic rhinosinusitis in a real life rhinology clinic setting.
Rhinology 2001;39(3):142-6.
2001: Fowler S J; Orr L C; Wilson A M; Sims E J; Lipworth B J
Dose-response for adrenal suppression with hydrofluoroalkane formulations of fluticasone propionate and beclomethasone dipropionate.
British journal of clinical pharmacology 2001;52(1):93-5.
2001: Wilson A M; Fowler S J; Martin S W; White P S; Gardiner Q; Lipworth B J
Evaluation of the importance of head and probe stabilisation in acoustic rhinometry.
Rhinology 2001;39(2):93-7.
2001: Wilson A M; Dempsey O J; Sims E J; Lipworth B J
A comparison of topical budesonide and oral montelukast in seasonal allergic rhinitis and asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2001;31(4):616-24.
2001: Fowler S J; Lipworth B J
Pharmacokinetics and systemic beta2-adrenoceptor-mediated responses to inhaled salbutamol.
British journal of clinical pharmacology 2001;51(4):359-62.
2001: Wilson A M; Dempsey O J; Sims E J; Lipworth B J
Evaluation of salmeterol or montelukast as second-line therapy for asthma not controlled with inhaled corticosteroids.
Chest 2001;119(4):1021-6.
2001: Fowler S J; Wilson A M; Griffiths E A; Lipworth B J
Comparative in vivo lung delivery of hydrofluoroalkane-salbutamol formulation via metered-dose inhaler alone, with plastic spacer, or with cardboard tube.
Chest 2001;119(4):1018-20.
2001: Wilson A M; Orr L C; Sims E J; Lipworth B J
Effects of monotherapy with intra-nasal corticosteroid or combined oral histamine and leukotriene receptor antagonists in seasonal allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2001;31(1):61-8.
2000: Aziz I; Wilson A M; Lipworth B J
Effects of once-daily formoterol and budesonide given alone or in combination on surrogate inflammatory markers in asthmatic adults.
Chest 2000;118(4):1049-58.
2000: Fowler S J; Dempsey O J; Sims E J; Lipworth B J
Screening for bronchial hyperresponsiveness using methacholine and adenosine monophosphate. Relationship to asthma severity and beta(2)-receptor genotype.
American journal of respiratory and critical care medicine 2000;162(4 Pt 1):1318-22.
2000: Wilson A M; Orr L C; Sims E J; Dempsey O J; Lipworth B J
Antiasthmatic effects of mediator blockade versus topical corticosteroids in allergic rhinitis and asthma.
American journal of respiratory and critical care medicine 2000;162(4 Pt 1):1297-301.
2000: Lipworth B J; White P S
Allergic inflammation in the unified airway: start with the nose.
Thorax 2000;55(10):878-81.
2000: Lipworth B J
The comparative safety/efficacy ratio of HFA-BDP.
Respiratory medicine 2000;94 Suppl D():S21-6.
2000: Lipworth B J
Targets for inhaled treatment.
Respiratory medicine 2000;94 Suppl D():S13-6.
2000: Wilson A M; Dempsey O J; Sims E J; Lipworth B J
Subjective and objective markers of treatment response in patients with seasonal allergic rhinitis.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2000;85(2):111-4.
2000: Lipworth B J; Dempsey O J; Aziz I; Wilson A M
Effects of adding a leukotriene antagonist or a long-acting beta(2)-agonist in asthmatic patients with the glycine-16 beta(2)-adrenoceptor genotype.
The American journal of medicine 2000;109(2):114-21.
2000: Lipworth B J; Dempsey O J; Aziz I
Functional antagonism with formoterol and salmeterol in asthmatic patients expressing the homozygous glycine-16 beta(2)-adrenoceptor polymorphism.
Chest 2000;118(2):321-8.
2000: McMahon A D; Lipworth B J; Davey P G; Morris A D; Macdonald T M
Continuity of prescribing with inhaled corticosteroids and control of asthma.
Pharmacoepidemiology and drug safety 2000;9(4):293-303.
2000: Lipworth B J
Therapeutic implications of non-genomic glucocorticoid activity.
Lancet 2000;356(9224):87-9.
2000: Lipworth B J; Jackson C M
Safety of inhaled and intranasal corticosteroids: lessons for the new millennium.
Drug safety : an international journal of medical toxicology and drug experience 2000;23(1):11-33.
2000: Wilson A; Dempsey O J; Sims E J; Coutie W J; Paterson M C; Lipworth B J
Evaluation of treatment response in patients with seasonal allergic rhinitis using domiciliary nasal peak inspiratory flow.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2000;30(6):833-8.
2000: Dempsey O J; Wilson A M; Sims E J; Mistry C; Lipworth B J
Additive bronchoprotective and bronchodilator effects with single doses of salmeterol and montelukast in asthmatic patients receiving inhaled corticosteroids.
Chest 2000;117(4):950-3.
2000: Wilson A M; Lipworth B J
Dose-response evaluation of the therapeutic index for inhaled budesonide in patients with mild-to-moderate asthma.
The American journal of medicine 2000;108(4):269-75.
2000: Wilson A M; Blumsohn A; Jung R T; Lipworth B J
Asthma and Cushing's syndrome.
Chest 2000;117(2):593-4.
2000: Lipworth B J; Aziz I
Bronchodilator response to albuterol after regular formoterol and effects of acute corticosteroid administration.
Chest 2000;117(1):156-62.
1999: Lipworth B J; Jackson C M
Pharmacokinetics of chlorofluorocarbon and hydrofluoroalkane metered-dose inhaler formulations of beclomethasone dipropionate.
British journal of clinical pharmacology 1999;48(6):866-8.
1999: Wilson A M; Lipworth B J
Short-term dose-response relationships for the relative systemic effects of oral prednisolone and inhaled fluticasone in asthmatic adults.
British journal of clinical pharmacology 1999;48(4):579-85.
1999: Wilson A M; Sims E J; Orr L C; Lipworth B J
Differences in lung bioavailability between different propellants for fluticasone propionate.
Lancet 1999;354(9187):1357-8.
1999: Dempsey O J; Wilson A M; Coutie W J; Lipworth B J
Evaluation of the effect of a large volume spacer on the systemic bioactivity of fluticasone propionate metered-dose inhaler.
Chest 1999;116(4):935-40.
1999: Aziz I; McFarlane L C; Lipworth B J
Comparative trough effects of formoterol and salmeterol on lymphocyte beta2-adrenoceptor--regulation and bronchodilatation.
European journal of clinical pharmacology 1999;55(6):431-6.
1999: Dempsey O J; Coutie W J; Wilson A M; Williams P; Lipworth B J
Evaluation of the buccal component of systemic absorption with inhaled fluticasone propionate.
Thorax 1999;54(7):614-7.
1999: Wilson A M; Dempsey O J; Coutie W J; Sims E J; Lipworth B J
Importance of drug-device interaction in determining systemic effects of inhaled corticosteroids.
Lancet 1999;353(9170):2128.
1999: Dempsey O J; Wilson A M; Lipworth B J
Spacer devices increase dose of inhaled corticosteroids delivered.
BMJ (Clinical research ed.) 1999;318(7200):1764.
1999: Aziz I; Lipworth B J
In vivo effect of albuterol on methacholine-contracted bronchi in conjunction with salmeterol and formoterol.
The Journal of allergy and clinical immunology 1999;103(5 Pt 1):816-22.
1999: Lipworth B J
Systemic adverse effects of inhaled corticosteroid therapy: A systematic review and meta-analysis.
Archives of internal medicine 1999;159(9):941-55.
1999: Wilson A M; Sims E J; Lipworth B J
Dose response with fluticasone propionate on adrenocortical activity and recovery of basal and stimulated responses after stopping treatment.
Clinical endocrinology 1999;50(3):329-35.
1999: Anhøj J; Bisgaard H; Lipworth B J
Effect of electrostatic charge in plastic spacers on the lung delivery of HFA-salbutamol in children.
British journal of clinical pharmacology 1999;47(3):333-6.
1999: Aziz I; Lipworth B J
A bolus of inhaled budesonide rapidly reverses airway subsensitivity and beta2-adrenoceptor down-regulation after regular inhaled formoterol.
Chest 1999;115(3):623-8.
1999: Lipworth B J; Hall I P; Aziz I; Tan K S; Wheatley A
Beta2-adrenoceptor polymorphism and bronchoprotective sensitivity with regular short- and long-acting beta2-agonist therapy.
Clinical science (London, England : 1979) 1999;96(3):253-9.
1999: Lipworth B J; Hall I P; Tan S; Aziz I; Coutie W
Effects of genetic polymorphism on ex vivo and in vivo function of beta2-adrenoceptors in asthmatic patients.
Chest 1999;115(2):324-8.
1999: Lipworth B J
Fortnightly review: modern drug treatment of chronic asthma.
BMJ (Clinical research ed.) 1999;318(7180):380-4.
1999: Wilson A M; Lipworth B J
24 hour and fractionated profiles of adrenocortical activity in asthmatic patients receiving inhaled and intranasal corticosteroids.
Thorax 1999;54(1):20-6.
1999: Lipworth B J
Leukotriene-receptor antagonists.
Lancet 1999;353(9146):57-62.
1999: Lipworth B J; Aziz I
A high dose of albuterol does not overcome bronchoprotective subsensitivity in asthmatic subjects receiving regular salmeterol or formoterol.
The Journal of allergy and clinical immunology 1999;103(1 Pt 1):88-92.
1998: Wilson A M; Brewster H J; Lipworth B J
Dose-response comparison of systemic bioactivity with inhaled budesonide and triamcinolone acetonide in asthmatic adults.
The Journal of allergy and clinical immunology 1998;102(5):751-6.
1998: Wilson A M; Sims E J; McFarlane L C; Lipworth B J
Effects of intranasal corticosteroids on adrenal, bone, and blood markers of systemic activity in allergic rhinitis.
The Journal of allergy and clinical immunology 1998;102(4 Pt 1):598-604.
1998: Wilson A M; McFarlane L C; Lipworth B J
Systemic bioactivity profiles of oral prednisolone and nebulized budesonide in adult asthmatics.
Chest 1998;114(4):1022-7.
1998: Wilson A M; Sims E J; Struthers A D; Lipworth B J
Inhaled corticosteroid therapy reduces the early morning peak in cortisol and aldosterone.
Clinical science (London, England : 1979) 1998;95(4):513-7.
1998: Kiely D G; Lee A F; Struthers A D; Lipworth B J
Nitric oxide: an important role in the maintenance of systemic and pulmonary vascular tone in man.
British journal of clinical pharmacology 1998;46(3):263-6.
1998: Aziz I; Tan K S; Hall I P; Devlin M M; Lipworth B J
Subsensitivity to bronchoprotection against adenosine monophosphate challenge following regular once-daily formoterol.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;12(3):580-4.
1998: Aziz I; McFarlane L C; Lipworth B J
Concomitant inhaled corticosteroid resensitises cardiac beta2-adrenoceptors in the presence of long-acting beta2-agonist therapy.
European journal of clinical pharmacology 1998;54(5):377-81.
1998: Lipworth B; Tan S; Devlin M; Aiken T; Baker R; Hendrick D
Effects of treatment with formoterol on bronchoprotection against methacholine.
The American journal of medicine 1998;104(5):431-8.
1998: Wilson A M; McFarlane L C; Lipworth B J
Effects of repeated once daily dosing of three intranasal corticosteroids on basal and dynamic measures of hypothalamic-pituitary-adrenal-axis activity.
The Journal of allergy and clinical immunology 1998;101(4 Pt 1):470-4.
1998: Aziz I; Hall I P; McFarlane L C; Lipworth B J
Beta2-adrenoceptor regulation and bronchodilator sensitivity after regular treatment with formoterol in subjects with stable asthma.
The Journal of allergy and clinical immunology 1998;101(3):337-41.
1998: Wilson A M; McFarlane L C; Lipworth B J
Effects of low and high doses of inhaled flunisolide and triamcinolone acetonide on basal and dynamic measures of adrenocortical activity in healthy volunteers.
The Journal of clinical endocrinology and metabolism 1998;83(3):922-5.
1998: Tan K S; McFarlane L C; Lipworth B J
Beta2-adrenoceptor regulation and function in female asthmatic patients receiving the oral combined contraceptive pill.
Chest 1998;113(2):278-82.
1998: Lipworth B J; Clark D J
Lung delivery of non-CFC salbutamol via small volume metal spacer and large volume plastic spacer devices compared with an open vent jet nebulizer.
British journal of clinical pharmacology 1998;45(2):160-3.
1998: Wilson A M; Clark D J; Devlin M M; McFarlane L C; Lipworth B J
Adrenocortical activity with repeated administration of one-daily inhaled fluticasone propionate and budesonide in asthmatic adults.
European journal of clinical pharmacology 1998;53(5):317-20.
1998: Tan K S; McFarlane L C; Lipworth B J
Concomitant administration of low-dose prednisolone protects against in vivo beta2-adrenoceptor subsensitivity induced by regular formoterol.
Chest 1998;113(1):34-41.
1997: Lipworth B J; Clark D J
Effects of airway calibre on lung delivery of nebulised salbutamol.
Thorax 1997;52(12):1036-9.
1997: Tan K S; McFarlane L C; Lipworth B J
Effects of oral and inhaled corticosteroid on lymphocyte beta2-adrenoceptor function in asthmatic patients.
British journal of clinical pharmacology 1997;44(6):565-8.
1997: Clark D J; Lipworth B J
Evaluation of corticotropin releasing factor stimulation and basal markers of hypothalamic-pituitary-adrenal axis suppression in asthmatic patients.
Chest 1997;112(5):1248-52.
1997: Lipworth B J; Clark D J; Koch P; Arbeeny C
Pharmacokinetics and extrapulmonary beta 2 adrenoceptor activity of nebulised racemic salbutamol and its R and S isomers in healthy volunteers.
Thorax 1997;52(10):849-52.
1997: Wilson A M; McFarlane L C; Lipworth B J
Dose-response effect for adrenal suppression with repeated twice daily inhaled fluticasone propionate and triamcinolone acetonide in adult asthmatics.
American journal of respiratory and critical care medicine 1997;156(4 Pt 1):1274-7.
1997: Lipworth B J
Treatment of acute asthma.
Lancet 1997;350 Suppl 2():SII18-23.
1997: Tan S; Hall I P; Dewar J; Dow E; Lipworth B
Association between beta 2-adrenoceptor polymorphism and susceptibility to bronchodilator desensitisation in moderately severe stable asthmatics.
Lancet 1997;350(9083):995-9.
1997: Lipworth B J; Clark D J
Lung delivery of salbutamol given by breath activated pressurized aerosol and dry powder inhaler devices.
Pulmonary pharmacology & therapeutics 1997;10(4):211-4.
1997: Lipworth B J; Clark D J; McFarlane L C
Adrenocortical activity with repeated twice daily dosing of fluticasone propionate and budesonide given via a large volume spacer to asthmatic school children.
Thorax 1997;52(8):686-9.
1997: Lipworth B J; Clark D J
Lung delivery of salbutamol by dry powder inhaler (Turbuhaler) and small volume antistatic metal spacer (Airomir CFC-free MDI plus NebuChamber).
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1997;10(8):1820-3.
1997: Tan K S; McFarlane L C; Lipworth B J
Loss of normal cyclical beta 2 adrenoceptor regulation and increased premenstrual responsiveness to adenosine monophosphate in stable female asthmatic patients.
Thorax 1997;52(7):608-11.
1997: Tan K S; Grove A; McLean A; Gnosspelius Y; Hall I P; Lipworth B J
Systemic corticosteriod rapidly reverses bronchodilator subsensitivity induced by formoterol in asthmatic patients.
American journal of respiratory and critical care medicine 1997;156(1):28-35.
1997: Lipworth B J
Airway subsensitivity with long-acting beta 2-agonists. Is there cause for concern?
Drug safety : an international journal of medical toxicology and drug experience 1997;16(5):295-308.
1997: Lipworth B J; Seckl J R
Measures for detecting systemic bioactivity with inhaled and intranasal corticosteroids.
Thorax 1997;52(5):476-82.
1997: Mathur R; Clark R A; Dhillon D P; Winter J H; Lipworth B J
Reaudit of acute asthma admissions using a severity marker stamp and determinants of an outcome measure.
Scottish medical journal 1997;42(2):49-52.
1997: Tan K S; McFarlane L C; Lipworth B J
Paradoxical down-regulation and desensitization of beta2-adrenoceptors by exogenous progesterone in female asthmatics.
Chest 1997;111(4):847-51.
1997: Tan K S; McFarlane L C; Lipworth B J
Modulation of airway reactivity and peak flow variability in asthmatics receiving the oral contraceptive pill.
American journal of respiratory and critical care medicine 1997;155(4):1273-7.
1997: Kiely D G; Cargill R I; Lipworth B J
Effects of frusemide and hypoxia on the pulmonary vascular bed in man.
British journal of clinical pharmacology 1997;43(3):309-13.
1997: Mathur R; Clark R A; Dhillon D P; Winter J H; Lipworth B J
A repeat audit of hospital discharge letters in patients admitted with acute asthma.
Scottish medical journal 1997;42(1):19-21.
1997: Kiely D G; Cargill R I; Struthers A D; Lipworth B J
Cardiopulmonary effects of endothelin-1 in man.
Cardiovascular research 1997;33(2):378-86.
1997: Kiely D G; Cargill R I; Wheeldon N M; Coutie W J; Lipworth B J
Haemodynamic and endocrine effects of type 1 angiotensin II receptor blockade in patients with hypoxaemic cor pulmonale.
Cardiovascular research 1997;33(1):201-8.
1997: Lipworth B J; Grove A
Evaluation of partial beta-adrenoceptor agonist activity.
British journal of clinical pharmacology 1997;43(1):9-14.
1997: Clark D J; Lipworth B J
Adrenal suppression with chronic dosing of fluticasone propionate compared with budesonide in adult asthmatic patients.
Thorax 1997;52(1):55-8.
1997: Clark D J; Lipworth B J
Dose-response of inhaled drugs in asthma. An update.
Clinical pharmacokinetics 1997;32(1):58-74.
1997: Lipworth B J; Clark D J
Comparative lung delivery of salbutamol given via Turbuhaler and Diskus dry powder inhaler devices.
European journal of clinical pharmacology 1997;53(1):47-9.
1997: Wilson A M; Clark D J; McFarlane L; Lipworth B J
Adrenal suppression with high doses of inhaled fluticasone propionate and triamcinolone acetonide in healthy volunteers.
European journal of clinical pharmacology 1997;53(1):33-7.
1997: Tan K S; McFarlane L C; Lipworth B J
Effect of exogenous female sex-steroid hormones on beta 2-adrenoceptors in healthy males.
European journal of clinical pharmacology 1997;52(4):281-3.
1996: Lipworth B J
Pharmacokinetics of inhaled drugs.
British journal of clinical pharmacology 1996;42(6):697-705.
1996: Cargill R I; Lipworth B J
Atrial natriuretic peptide and brain natriuretic peptide in cor pulmonale. Hemodynamic and endocrine effects.
Chest 1996;110(5):1220-5.
1996: Clark D J; Lipworth B J
Effect of multiple actuations, delayed inhalation and antistatic treatment on the lung bioavailability of salbutamol via a spacer device.
Thorax 1996;51(10):981-4.
1996: Clark D J; Clark R A; Lipworth B J
Adrenal suppression with inhaled budesonide and fluticasone propionate given by large volume spacer to asthmatic children.
Thorax 1996;51(9):941-3.
1996: Lipworth B J
Clinical pharmacology of beta 3-adrenoceptors.
British journal of clinical pharmacology 1996;42(3):291-300.
1996: Kiely D G; Cargill R I; Lipworth B J
Angiotensin II receptor blockade and effects on pulmonary hemodynamics and hypoxic pulmonary vasoconstriction in humans.
Chest 1996;110(3):698-703.
1996: Grove A; Lipworth B J; Reid P; Smith R P; Ramage L; Ingram C G; Jenkins R J; Winter J H; Dhillon D P
Effects of regular salmeterol on lung function and exercise capacity in patients with chronic obstructive airways disease.
Thorax 1996;51(7):689-93.
1996: Grove A; Lipworth B J
Effects of prior treatment with salmeterol and formoterol on airway and systemic beta 2 responses to fenoterol.
Thorax 1996;51(6):585-9.
1996: Tan K S; McFarlane L C; Coutie W J; Lipworth B J
Effects of exogenous female sex-steroid hormones on lymphocyte beta 2-adrenoceptors in normal females.
British journal of clinical pharmacology 1996;41(5):414-6.
1996: Kiely D G; Cargill R I; Lipworth B J
Effects of hypercapnia on hemodynamic, inotropic, lusitropic, and electrophysiologic indices in humans.
Chest 1996;109(5):1215-21.
1996: Clark D J; Lipworth B J
Lung bioavailability of chlorofluorocarbon free, dry powder and chlorofluorocarbon containing formulations of salbutamol.
British journal of clinical pharmacology 1996;41(3):247-9.
1996: Clark D J; Gordon-Smith J; McPhate G; Clark G; Lipworth B J
Lung bioavailability of generic and innovator salbutamol metered dose inhalers.
Thorax 1996;51(3):325-6.
1996: Clark D J; Grove A; Cargill R I; Lipworth B J
Comparative adrenal suppression with inhaled budesonide and fluticasone propionate in adult asthmatic patients.
Thorax 1996;51(3):262-6.
1996: Lipworth B J
Airway and systemic effects of inhaled corticosteroids in asthma: dose response relationship.
Pulmonary pharmacology 1996;9(1):19-27.
1996: Cargill R I; Lipworth B J
Lisinopril attenuates acute hypoxic pulmonary vasoconstriction in humans.
Chest 1996;109(2):424-9.
1996: Tan K S; Grove A; Cargill R I; McFarlane L C; Lipworth B J
Effects of inhaled fluticasone propionate and oral prednisolone on lymphocyte beta 2-adrenoceptor function in asthmatic patients.
Chest 1996;109(2):343-7.
1996: Grove A; Lipworth B J
Evaluation of the beta 2 adrenoceptor agonist/antagonist activity of formoterol and salmeterol.
Thorax 1996;51(1):54-8.
1996: Clark D J; Tan K S; Lipworth B J
Evaluation of plasma and urinary salbutamol levels in COPD.
European journal of clinical pharmacology 1996;51(1):91-3.
1996: Cargill R I; McFarlane L C; Coutie W J; Lipworth B J
Acute neurohormonal responses to hypoxaemia in man.
European journal of applied physiology and occupational physiology 1996;72(3):256-60.
1996: Grove A; McFarlane L C; Jackson C M; Lipworth B J
Effects of short-term exposure to high-dose inhaled corticosteroids on novel markers of bone metabolism.
European journal of clinical pharmacology 1996;50(4):275-7.
1995: Kiely D G; Cargill R I; Lipworth B J
Acute hypoxic pulmonary vasoconstriction in man is attenuated by type I angiotensin II receptor blockade.
Cardiovascular research 1995;30(6):875-80.
1995: Cargill R I; Lipworth B J
Acute effects of ANP and BNP on hypoxic pulmonary vasoconstriction in humans.
British journal of clinical pharmacology 1995;40(6):585-90.
1995: Cargill R I; Kiely D G; Clark R A; Lipworth B J
Hypoxaemia and release of endothelin-1.
Thorax 1995;50(12):1308-10.
1995: Smith R P; Lipworth B J; Cree I A; Spiers E M; Winter J H
C-reactive protein. A clinical marker in community-acquired pneumonia.
Chest 1995;108(5):1288-91.
1995: Kiely D G; Cargill R I; Lipworth B J
Cardiopulmonary interactions of salbutamol and hypoxaemia in healthy young volunteers.
British journal of clinical pharmacology 1995;40(4):313-8.
1995: Cargill R I; Kiely D G; Lipworth B J
Left ventricular systolic performance during acute hypoxemia.
Chest 1995;108(4):899-902.
1995: Kiely D G; Cargill R I; Grove A; Struthers A D; Lipworth B J
Abnormal myocardial repolarisation in response to hypoxaemia and fenoterol.
Thorax 1995;50(10):1062-6.
1995: Cargill R I; Kiely D G; Lipworth B J
Adverse effects of hypoxaemia on diastolic filling in humans.
Clinical science (London, England : 1979) 1995;89(2):165-9.
1995: Cargill R I; Lipworth B J
The role of the renin-angiotensin and natriuretic peptide systems in the pulmonary vasculature.
British journal of clinical pharmacology 1995;40(1):11-8.
1995: Grove A; Lipworth B J
Bronchodilator subsensitivity to salbutamol after twice daily salmeterol in asthmatic patients.
Lancet 1995;346(8969):201-6.
1995: Newnham D M; Grove A; McDevitt D G; Lipworth B J
Subsensitivity of bronchodilator and systemic beta 2 adrenoceptor responses after regular twice daily treatment with eformoterol dry powder in asthmatic patients.
Thorax 1995;50(5):497-504.
1995: Smith R P; Lipworth B J
C-reactive protein in simple community-acquired pneumonia.
Chest 1995;107(4):1028-31.
1995: Grove A; Lipworth B J
Tolerance with beta 2-adrenoceptor agonists: time for reappraisal.
British journal of clinical pharmacology 1995;39(2):109-18.
1995: Cargill R I; Lipworth B J
Pulmonary vasorelaxant activity of atrial natriuretic peptide and brain natriuretic peptide in humans.
Thorax 1995;50(2):183-5.
1995: Grove A; McFarlane L C; Lipworth B J
Expression of the beta 2 adrenoceptor partial agonist/antagonist activity of salbutamol in states of low and high adrenergic tone.
Thorax 1995;50(2):134-8.
1995: Cargill R I; Struthers A D; Lipworth B J
Human C-type natriuretic peptide: effects on the haemodynamic and endocrine responses to angiotensin II.
Cardiovascular research 1995;29(1):108-11.
1995: Lipworth B J; Newnham D M; Clark R A; Dhillon D P; Winter J H; McDevitt D G
Comparison of the relative airways and systemic potencies of inhaled fenoterol and salbutamol in asthmatic patients.
Thorax 1995;50(1):54-61.
1995: Cargill R I; Struthers A D; Lipworth B J
Comparative effects of atrial natriuretic peptide and brain natriuretic peptide on the aldosterone and pressor responses to angiotensin II in man.
Clinical science (London, England : 1979) 1995;88(1):81-6.
1995: Lang C C; McAlpine H M; Kennedy N; Rahman A R; Lipworth B J; Struthers A D
Effects of lisinopril on congestive heart failure in normotensive patients with diastolic dysfunction but intact systolic function.
European journal of clinical pharmacology 1995;49(1-2):15-9.
1995: Grove A; Lipworth B J; Ingram C G; Clark R A; Dhillon D P
A comparison of the effects of prednisolone and mianserin on ventilatory, exercise and psychometric parameters in patients with chronic obstructive pulmonary disease.
European journal of clinical pharmacology 1995;48(1):13-8.
1994: Grove A; Allam C; McFarlane L C; McPhate G; Jackson C M; Lipworth B J
A comparison of the systemic bioactivity of inhaled budesonide and fluticasone propionate in normal subjects.
British journal of clinical pharmacology 1994;38(6):527-32.
1994: Cargill R I; Barr C S; Coutie W J; Struthers A D; Lipworth B J
C-type natriuretic peptide levels in cor pulmonale and in congestive heart failure.
Thorax 1994;49(12):1247-9.
1994: Cargill R I; Boyter A C; Lipworth B J
Reversible myocardial ischaemia following vincristine containing chemotherapy.
Respiratory medicine 1994;88(9):709-10.
1994: Cargill R I; Lipworth B J
Acute effects of hypoxaemia and angiotensin II in the human pulmonary vascular bed.
Pulmonary pharmacology 1994;7(5):305-10.
1994: Cargill R I; Kiely D G; Lipworth B J
Hypoxaemia and the renin-angiotensin system: new answers for old questions.
Pulmonary pharmacology 1994;7(5):279-84.
1994: Lipworth B J; Grove A; Jackson C M
Asthma control.
Lancet 1994;344(8924):760.
1994: Newnham D M; Lipworth B J
Nebuliser performance, pharmacokinetics, airways and systemic effects of salbutamol given via a novel nebuliser delivery system ("Ventstream").
Thorax 1994;49(8):762-70.
1994: Cargill R I; Coutie W J; Lipworth B J
The effects of angiotensin II on circulating levels of natriuretic peptides.
British journal of clinical pharmacology 1994;38(2):139-42.
1994: Wheeldon N M; McDevitt D G; Lipworth B J
The effects of lower than conventional doses of oral nadolol on relative beta 1/beta 2-adrenoceptor blockade.
British journal of clinical pharmacology 1994;38(2):103-8.
1994: Newnham D M; McDevitt D G; Lipworth B J
Bronchodilator subsensitivity after chronic dosing with eformoterol in patients with asthma.
The American journal of medicine 1994;97(1):29-37.
1994: Lang C C; Prasad N; McAlpine H M; Macleod C; Lipworth B J; MacDonald T M; Struthers A D
Increased plasma levels of brain natriuretic peptide in patients with isolated diastolic dysfunction.
American heart journal 1994;127(6):1635-6.
1994: Wheeldon N M; Newnham D M; Coutie W J; Peters J A; McDevitt D G; Lipworth B J
Influence of sex-steroid hormones on the regulation of lymphocyte beta 2-adrenoceptors during the menstrual cycle.
British journal of clinical pharmacology 1994;37(6):583-8.
1994: Lipworth B J; Dagg K D
Vasoconstrictor effects of angiotensin II on the pulmonary vascular bed.
Chest 1994;105(5):1360-4.
1994: Ramage L; Lipworth B J; Ingram C G; Cree I A; Dhillon D P
Reduced protection against exercise induced bronchoconstriction after chronic dosing with salmeterol.
Respiratory medicine 1994;88(5):363-8.
1994: Wheeldon N M; McDevitt D G; Lipworth B J
Cardiac effects of the beta 3-adrenoceptor agonist BRL35135 in man.
British journal of clinical pharmacology 1994;37(4):363-9.
1994: Lipworth B J; Dagg K D
Comparative effects of angiotensin II on Doppler parameters of left and right heart systolic and diastolic blood flow.
British journal of clinical pharmacology 1994;37(3):273-8.
1994: Wheeldon N M; McDevitt D G; McFarlane L C; Lipworth B J
Beta-adrenoceptor subtypes mediating the metabolic effects of BRL 35135 in man.
Clinical science (London, England : 1979) 1994;86(3):331-7.
1994: Newnham D M; Wheeldon N M; McFarlane L C; Clark G A; McDevitt D G; Lipworth B J
Extrapulmonary beta 2-responses to intravenous salbutamol during the menstrual cycle.
European journal of clinical pharmacology 1994;46(6):511-5.
1993: Newnham D M; Ingram C G; Mackie A; Lipworth B J
Beta-adrenoceptor subtypes mediating the airways response to BRL 35135 in man.
British journal of clinical pharmacology 1993;36(6):567-71.
1993: Newnham D M; McDevitt D G; Lipworth B J
Comparison of the extrapulmonary beta2-adrenoceptor responses and pharmacokinetics of salbutamol given by standard metered dose-inhaler and modified actuator device.
British journal of clinical pharmacology 1993;36(5):445-50.
1993: Newnham D M; Dhillon D P; Winter J H; Jackson C M; Clark R A; Lipworth B J
Bronchodilator reversibility to low and high doses of terbutaline and ipratropium bromide in patients with chronic obstructive pulmonary disease.
Thorax 1993;48(11):1151-5.
1993: Wheeldon N M; McDevitt D G; Lipworth B J
Do beta 3-adrenoceptors mediate metabolic responses to isoprenaline.
The Quarterly journal of medicine 1993;86(9):595-600.
1993: Lipworth B J; Allan J; Jackson C M; Dhillon P D; Winter J H; Clark R A
An audit of hospital discharge letters in patients admitted with acute asthma. Tayside Asthma Audit Group.
Scottish medical journal 1993;38(4):116-9.
1993: Newnham D M; Wheeldon N M; Lipworth B J; McDevitt D G
Single dosing comparison of the relative cardiac beta 1/beta 2 activity of inhaled fenoterol and salbutamol in normal subjects.
Thorax 1993;48(6):656-8.
1993: Wheeldon N M; McDevitt D G; Lipworth B J
Investigation of putative cardiac beta 3-adrenoceptors in man.
The Quarterly journal of medicine 1993;86(4):255-61.
1993: Newnham D M; Coutie W J; McFarlane L C; Lipworth B J
Comparison of parameters of in vitro lymphocyte beta 2-adrenoceptor function in normal and asthmatic subjects.
European journal of clinical pharmacology 1993;45(6):535-8.
1992: Rahman A R; McDevitt D G; Struthers A D; Lipworth B J
Sex differences in hypokalaemic and electrocardiographic effects of inhaled terbutaline.
Thorax 1992;47(12):1056-9.
1992: Lang C C; Coutie W J; Struthers A D; Dhillon D P; Winter J H; Lipworth B J
Elevated levels of brain natriuretic peptide in acute hypoxaemic chronic obstructive pulmonary disease.
Clinical science (London, England : 1979) 1992;83(5):529-33.
1992: Wheeldon N M; McDevitt D G; Lipworth B J
Selectivity of antagonist and partial agonist activity of celiprolol in normal subjects.
British journal of clinical pharmacology 1992;34(4):337-43.
1992: Lipworth B J; Jackson C M; Ziyaie D; Winter J H; Dhillon P D; Clark R A
An audit of acute asthma admissions to a respiratory unit.
Health bulletin 1992;50(5):389-98.
1992: Rahman A R; McDevitt D G; Struthers A D; Lipworth B J
The effects of enalapril and spironolactone on terbutaline-induced hypokalemia.
Chest 1992;102(1):91-5.
1992: Wheeldon N M; McDevitt D G; Lipworth B J
Evaluation of in vivo partial beta 1/beta 2-agonist activity: a dose-ranging study with carteolol.
British journal of clinical pharmacology 1992;33(4):411-6.
1992: Lipworth B J; McDevitt D G
Inhaled beta 2-adrenoceptor agonists in asthma: help or hindrance?
British journal of clinical pharmacology 1992;33(2):129-38.
1992: Lipworth B J
Risks versus benefits of inhaled beta 2-agonists in the management of asthma.
Drug safety : an international journal of medical toxicology and drug experience 1992;7(1):54-70.
1991: Newnham D M; McDevitt D G; Lipworth B J
The effects of frusemide and triamterene on the hypokalaemic and electrocardiographic responses to inhaled terbutaline.
British journal of clinical pharmacology 1991;32(5):630-2.
1991: Motwani J G; Lipworth B J
Clinical pharmacokinetics of drug administered buccally and sublingually.
Clinical pharmacokinetics 1991;21(2):83-94.
1991: Lipworth B J; Clark R A; McDevitt D G
Measurement of normal human airways response to beta-adrenoceptor stimulation using a forced oscillation technique.
Journal of clinical pharmacy and therapeutics 1991;16(3):187-91.
1991: Wheeldon N M; Newnham D M; Fraser G C; McDevitt D G; Lipworth B J
The effect of pindolol on creatine kinase is not due to beta 2-adrenoceptor partial agonist activity.
British journal of clinical pharmacology 1991;31(6):723-4.
1991: Lipworth B J; Irvine N A; McDevitt D G
The effects of time and dose on the relative beta 1- and beta 2-adrenoceptor antagonism of betaxolol and atenolol.
British journal of clinical pharmacology 1991;31(2):154-9.
1991: Lipworth B J; Tregaskis B F; McDevitt D G
Comparison of hypokalaemic, electrocardiographic and haemodynamic responses to inhaled isoprenaline and salbutamol in young and elderly subjects.
European journal of clinical pharmacology 1991;40(3):255-60.
1991: Lipworth B J; Irvine N A; McDevitt D G
A dose-ranging study to evaluate the beta 1-adrenoceptor selectivity of bisoprolol.
European journal of clinical pharmacology 1991;40(2):135-9.
1991: Lipworth B J; Irvine N A; McDevitt D G
The effects of chronic dosing on the beta 1 and beta 2-adrenoceptor antagonism of betaxolol and atenolol.
European journal of clinical pharmacology 1991;40(5):467-71.
1990: Lipworth B J; McDevitt D G; Struthers A D
Hypokalemic and ECG sequelae of combined beta-agonist/diuretic therapy. Protection by conventional doses of spironolactone but not triamterene.
Chest 1990;98(4):811-5.
1990: Lipworth B J; Clark R A; Dhillon D P; McDevitt D G
Comparison of the effects of prolonged treatment with low and high doses of inhaled terbutaline on beta-adrenoceptor responsiveness in patients with chronic obstructive pulmonary disease.
The American review of respiratory disease 1990;142(2):338-42.
1990: Irvine N A; Lipworth B J; McDevitt D G
A dose-ranging study to evaluate the beta-adrenoceptor selectivity of single doses of betaxolol.
British journal of clinical pharmacology 1990;30(1):119-26.
1990: Lipworth B J; McDevitt D G; Struthers A D
Electrocardiographic changes induced by inhaled salbutamol after treatment with bendrofluazide: effects of replacement therapy with potassium, magnesium and triamterene.
Clinical science (London, England : 1979) 1990;78(3):255-9.
1990: Lipworth B J; Clark R A; Dhillon D P; Palmer J B; McDevitt D G
Comparison of the efficacy and systemic effects of 4 mg and 8 mg formulations of salbutamol controlled release in patients with asthma.
European journal of clinical pharmacology 1990;39(3):281-5.
1990: Lipworth B J; Clark R A; Dhillon D P; McDevitt D G
Subsensitivity of beta-adrenoceptor responses in asthmatic patients taking regular low dose inhaled salbutamol.
European journal of clinical pharmacology 1990;38(2):203-5.
1989: Lipworth B J; Tregaskis B F; McDevitt D G
Beta-adrenoceptor responses to inhaled salbutamol in the elderly.
British journal of clinical pharmacology 1989;28(6):725-9.
1989: Lipworth B J; Struthers A D; McDevitt D G
Tachyphylaxis to systemic but not to airway responses during prolonged therapy with high dose inhaled salbutamol in asthmatics.
The American review of respiratory disease 1989;140(3):586-92.
1989: Lipworth B J; Brown R A; McDevitt D G
Assessment of airways, tremor and chronotropic responses to inhaled salbutamol in the quantification of beta 2-adrenoceptor blockade.
British journal of clinical pharmacology 1989;28(1):95-102.
1989: Lipworth B J; McDevitt D G; Struthers A D
Prior treatment with diuretic augments the hypokalemic and electrocardiographic effects of inhaled albuterol.
The American journal of medicine 1989;86(6 Pt 1):653-7.
1989: Lipworth B J; McMurray J J; Clark R A; Struthers A D
Development of persistent late onset asthma following treatment with captopril.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1989;2(6):586-8.
1989: Lipworth B J; McDevitt D G; Struthers A D
Systemic beta-adrenoceptor responses to salbutamol given by metered-dose inhaler alone and with pear shaped spacer attachment: comparison of electrocardiographic, hypokalaemic and haemodynamic effects.
British journal of clinical pharmacology 1989;27(6):837-42.
1989: Lipworth B J; Clark R A; Fraser C G; McDevitt D G
The biochemical effects of high-dose inhaled salbutamol in patients with asthma.
European journal of clinical pharmacology 1989;36(4):357-60.
1989: Lipworth B J; Clark R A; Dhillon D P; Moreland T A; Struthers A D; Clark G A; McDevitt D G
Pharmacokinetics, efficacy and adverse effects of sublingual salbutamol in patients with asthma.
European journal of clinical pharmacology 1989;37(6):567-71.
1989: Lipworth B J; Clark R A; Dhillon D P; Charter M K; Palmer J B; McDevitt D G
Single dose and steady-state pharmacokinetics of 4 mg and 8 mg oral salbutamol controlled-release in patients with bronchial asthma.
European journal of clinical pharmacology 1989;37(1):49-52.
1989: Lipworth B J; McFarlane L C; Coutie W J; McDevitt D G
Evaluation of the metabolic responses to inhaled salbutamol in the measurement of beta 2-adrenoceptor blockade.
European journal of clinical pharmacology 1989;37(3):297-300.
1989: Lipworth B J; McDevitt D G
Beta-adrenoceptor responses to inhaled salbutamol in normal subjects.
European journal of clinical pharmacology 1989;36(3):239-45.
1988: Lipworth B J; Clark R A; Dhillon D P; Brown R A; McDevitt D G
Beta-adrenoceptor responses to high doses of inhaled salbutamol in patients with bronchial asthma.
British journal of clinical pharmacology 1988;26(5):527-33.

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