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Jennifer Liras

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Chemicals & Drugs

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TOP 3
Kevin D Freeman-Cook; Lawrence A Reiter; Mark C Noe; Amy S Antipas; dennis danley; Kaushik Datta; James T Downs; Shane Eisenbeis; James D Eskra; David J Garmene; Elaine M Greer; Richard J Griffiths; Roberto Guzman; Joel R Hardink; Fouad Janat; Christopher S Jones; Gary J Martinelli; Peter G Mitchell; Ellen R Laird; Jennifer L Liras; Lori L Lopresti-Morrow; Jayvardhan Pandit; Usa D Reilly; Donald Robertson; Marcie L Vaughn-Bowser; Lilli A Wolf-Gouviea; Sue A Yocum
Potent, selective spiropyrrolidine pyrimidinetrione inhibitors of MMP-13.
Lawrence A Reiter; Kevin D Freeman-Cook; Christopher S Jones; Gary J Martinelli; Amy S Antipas; Martin A Berliner; Kaushik Datta; James T Downs; James D Eskra; Michael D Forman; Elaine M Greer; Roberto Guzman; Joel R Hardink; Fouad Janat; Nandell F Keene; Ellen R Laird; Jennifer L Liras; Lori L Lopresti-Morrow; Peter G Mitchell; Jayvardhan Pandit; Donald Robertson; Diana Sperger; Marcie L Vaughn-Bowser; Darra M Waller; Sue A Yocum
Potent, selective pyrimidinetrione-based inhibitors of MMP-13.
Mark C Noe; Vijayalakshmi Natarajan; Sheri L Snow; Lilli A Wolf-Gouveia; Peter G Mitchell; Lori L Lopresti-Morrow; Lisa M Reeves; Sue A Yocum; Ivan G Otterness; Marcia A Bliven; Thomas J Carty; John T Barberia; Francis J Sweeney; Jennifer L Liras; Marcie Vaughn
Discovery of 3-OH-3-methylpipecolic hydroxamates: potent orally active inhibitors of aggrecanase and MMP-13.

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All Publications

2007: Kevin D Freeman-Cook; Lawrence A Reiter; Mark C Noe; Amy S Antipas; dennis danley; Kaushik Datta; James T Downs; Shane Eisenbeis; James D Eskra; David J Garmene; Elaine M Greer; Richard J Griffiths; Roberto Guzman; Joel R Hardink; Fouad Janat; Christopher S Jones; Gary J Martinelli; Peter G Mitchell; Ellen R Laird; Jennifer L Liras; Lori L Lopresti-Morrow; Jayvardhan Pandit; Usa D Reilly; Donald Robertson; Marcie L Vaughn-Bowser; Lilli A Wolf-Gouviea; Sue A Yocum
Potent, selective spiropyrrolidine pyrimidinetrione inhibitors of MMP-13.
Bioorganic & medicinal chemistry letters 2007;17(23):6529-34.
2006: Lawrence A Reiter; Kevin D Freeman-Cook; Christopher S Jones; Gary J Martinelli; Amy S Antipas; Martin A Berliner; Kaushik Datta; James T Downs; James D Eskra; Michael D Forman; Elaine M Greer; Roberto Guzman; Joel R Hardink; Fouad Janat; Nandell F Keene; Ellen R Laird; Jennifer L Liras; Lori L Lopresti-Morrow; Peter G Mitchell; Jayvardhan Pandit; Donald Robertson; Diana Sperger; Marcie L Vaughn-Bowser; Darra M Waller; Sue A Yocum
Potent, selective pyrimidinetrione-based inhibitors of MMP-13.
Bioorganic & medicinal chemistry letters 2006;16(22):5822-6.
2005: Mark C Noe; Vijayalakshmi Natarajan; Sheri L Snow; Lilli A Wolf-Gouveia; Peter G Mitchell; Lori L Lopresti-Morrow; Lisa M Reeves; Sue A Yocum; Ivan G Otterness; Marcia A Bliven; Thomas J Carty; John T Barberia; Francis J Sweeney; Jennifer L Liras; Marcie Vaughn
Discovery of 3-OH-3-methylpipecolic hydroxamates: potent orally active inhibitors of aggrecanase and MMP-13.
Bioorganic & medicinal chemistry letters 2005;15(14):3385-8.
2005: Mark C Noe; Vijayalakshmi Natarajan; Sheri L Snow; Peter G Mitchell; Lori L Lopresti-Morrow; Lisa M Reeves; Sue A Yocum; Thomas J Carty; John A Barberia; Francis J Sweeney; Jennifer L Liras; Marcie Vaughn; Joel R Hardink; Joel M Hawkins; Christopher Tokar
Discovery of 3,3-dimethyl-5-hydroxypipecolic hydroxamate-based inhibitors of aggrecanase and MMP-13.
Bioorganic & medicinal chemistry letters 2005;15(11):2808-11.
2005: Julian A Blagg; Mark C Noe; Lilli A Wolf-Gouveia; Lawrence A Reiter; Ellen R Laird; Shang-Poa P Chang; dennis danley; James T Downs; Nancy C Elliott; James D Eskra; Richard J Griffiths; Joel R Hardink; Amber I Haugeto; Christopher S Jones; Jennifer L Liras; Lori L Lopresti-Morrow; Peter G Mitchell; Jayvardhan Pandit; Ralph P Robinson; Chakrapani Subramanyam; Marcie L Vaughn-Bowser; Sue A Yocum
Potent pyrimidinetrione-based inhibitors of MMP-13 with enhanced selectivity over MMP-14.
Bioorganic & medicinal chemistry letters 2005;15(7):1807-10.
2004: Mark C Noe; Sheri L Snow; Lilli A Wolf-Gouveia; Peter G Mitchell; Lori L Lopresti-Morrow; Lisa M Reeves; Sue A Yocum; Jennifer L Liras; Marcie Vaughn
3-Hydroxy-4-arylsulfonyltetrahydropyranyl-3-hydroxamic acids are novel inhibitors of MMP-13 and aggrecanase.
Bioorganic & medicinal chemistry letters 2004;14(18):4727-30.
2004: Lawrence A Reiter; Ralph P Robinson; Kim F McClure; Christopher S Jones; Matthew R Reese; Peter G Mitchell; Ivan G Otterness; Marcia L Bliven; Jennifer L Liras; Santo R Cortina; Kathleen M Donahue; James D Eskra; Richard J Griffiths; Mary E Lame; Arturo Lopez-Anaya; Gary J Martinelli; Shunda M McGahee; Sue A Yocum; Lori L Lopresti-Morrow; Lisa M Tobiassen; Marcie L Vaughn-Bowser
Pyran-containing sulfonamide hydroxamic acids: potent MMP inhibitors that spare MMP-1.
Bioorganic & medicinal chemistry letters 2004;14(13):3389-95.
2003: Michael A Letavic; John T Barberia; Thomas J Carty; Joel R Hardink; Jennifer L Liras; Lori L Lopresti-Morrow; Peter G Mitchell; Mark C Noe; Lisa M Reeves; Sheri L Snow; Ethan J Stam; Francis J Sweeney; Marcie Vaughn; Chul H Yu
Synthesis and biological activity of piperazine-based dual MMP-13 and TNF-alpha converting enzyme inhibitors.
Bioorganic & medicinal chemistry letters 2003;13(19):3243-6.