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Michael Lisanti
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Research Profile (preview)
Chemicals & Drugs
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Anatomy
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Network (preview)
69
Pestell, Richard
50
Sotgia, Federica
47
Scherer, Philipp
36
Frank, Philippe
32
Galbiati, Ferruccio
30
Minetti, Carlo
27
Razani, Babak
25
Tanowitz, Herbert
23
Cohen, Alex
22
Bonuccelli, Gloria
22
Volonte, Daniela
22
Williams, Terence
21
Sargiacomo, Massimo
20
Schubert, William
20
Engelman, Jeffery
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All Publications
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2009: Wu Karen N; Emmons Robert V B; Lisanti Michael P; Farber John L; Witkiewicz Agnieszka K
Foxp3-expressing T regulatory cells and mast cells in acute graft-versus-host disease of the skin.
Cell cycle (Georgetown, Tex.) 2009;8(21):3593-7.
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2009: Zhou Jie; Zhang Wei; Liang Bing; Casimiro Mathew C; Whitaker-Menezes Diana; Wang Min; Lisanti Michael P; Lanza-Jacoby Susan; Pestell Richard G; Wang Chenguang
PPARgamma activation induces autophagy in breast cancer cells.
The international journal of biochemistry & cell biology 2009;41(11):2334-42.
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2009: Felicetti Federica; Parolini Isabella; Bottero Lisabianca; Fecchi Katia; Errico Maria Cristina; Raggi Carla; Biffoni Mauro; Spadaro Francesca; Lisanti Michael P; Sargiacomo Massimo; Carè Alessandra
Caveolin-1 tumor-promoting role in human melanoma.
International journal of cancer. Journal international du cancer 2009;125(7):1514-22.
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2009: Di Vizio Dolores; Morello Matteo; Sotgia Federica; Pestell Richard G; Freeman Michael R; Lisanti Michael P
An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease and epithelial Akt activation.
Cell cycle (Georgetown, Tex.) 2009;8(15):2420-4.
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2009: Nan Fangfang; Lü Qingtao; Zhou Jie; Cheng Lei; Popov Vladimir M; Wei Shuangyan; Kong Beihua; Pestell Richard G; Lisanti Michael P; Jiang Jie; Wang Chenguang
Altered expression of DACH1 and cyclin D1 in endometrial cancer.
Cancer biology & therapy 2009;8(16):1534-9.
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2009: Nagajyothi Fnu; Desruisseaux Mahalia S; Weiss Louis M; Chua Streamson; Albanese Chris; Machado Fabiana S; Esper Lisia; Lisanti Michael P; Teixeira Mauro M; Scherer Philipp E; Tanowitz Herbert B
Chagas disease, adipose tissue and the metabolic syndrome.
Memórias do Instituto Oswaldo Cruz 2009;104 Suppl 1():219-25.
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2009: Witkiewicz Agnieszka K; Dasgupta Abhijit; Nguyen Katherine H; Liu Chengbao; Kovatich Albert J; Schwartz Gordon F; Pestell Richard G; Sotgia Federica; Rui Hallgeir; Lisanti Michael P
Stromal caveolin-1 levels predict early DCIS progression to invasive breast cancer.
Cancer biology & therapy 2009;8(11):1071-9.
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2009: Witkiewicz Agnieszka K; Casimiro Mathew C; Dasgupta Abhijit; Mercier Isabelle; Wang Chenguang; Bonuccelli Gloria; Jasmin Jean-François; Frank Philippe G; Pestell Richard G; Kleer Celina G; Sotgia Federica; Lisanti Michael P
Towards a new "stromal-based" classification system for human breast cancer prognosis and therapy.
Cell cycle (Georgetown, Tex.) 2009;8(11):1654-8.
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2009: Brody Jonathan R; Costantino Christina L; Berger Adam C; Sato Takami; Lisanti Michael P; Yeo Charles J; Emmons Robert V; Witkiewicz Agnieszka K
Expression of indoleamine 2,3-dioxygenase in metastatic malignant melanoma recruits regulatory T cells to avoid immune detection and affects survival.
Cell cycle (Georgetown, Tex.) 2009;8(12):1930-4.
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2009: Rodriguez Olga C; Lai Edwin W; Vissapragada Sarada; Cromelin Caroline; Avetian Maral; Salinas Patricia; Ramos Hida; Kallakury Bhaskar; Casimiro Mathew; Lisanti Michael P; Tanowitz Herbert B; Pacak Karel; Glazer Robert I; Avantaggiati Maria; Albanese Chris
A reduction in Pten tumor suppressor activity promotes ErbB-2-induced mouse prostate adenocarcinoma formation through the activation of signaling cascades downstream of PDK1.
The American journal of pathology 2009;174(6):2051-60.
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2009: Witkiewicz Agnieszka K; Dasgupta Abhijit; Sotgia Federica; Mercier Isabelle; Pestell Richard G; Sabel Michael; Kleer Celina G; Brody Jonathan R; Lisanti Michael P
An absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancers.
The American journal of pathology 2009;174(6):2023-34.
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2009: Mercier Isabelle; Jasmin Jean-Francois; Pavlides Stephanos; Minetti Carlo; Flomenberg Neal; Pestell Richard G; Frank Philippe G; Sotgia Federica; Lisanti Michael P
Clinical and translational implications of the caveolin gene family: lessons from mouse models and human genetic disorders.
Laboratory investigation; a journal of technical methods and pathology 2009;89(6):614-23.
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2009: Bonuccelli Gloria; Casimiro Mathew C; Sotgia Federica; Wang Chenguang; Liu Manran; Katiyar Sanjay; Zhou Jie; Dew Elliott; Capozza Franco; Daumer Kristin M; Minetti Carlo; Milliman Janet N; Alpy Fabien; Rio Marie-Christine; Tomasetto Catherine; Mercier Isabelle; Flomenberg Neal; Frank Philippe G; Pestell Richard G; Lisanti Michael P
Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature.
The American journal of pathology 2009;174(5):1650-62.
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2009: Mercier Isabelle; Bryant Kelly G; Sotgia Federica; Bonuccelli Gloria; Witkiewicz Agnieszka K; Dasgupta Abhijit; Jasmin Jean-François; Pestell Richard G; Lisanti Michael P
Using Caveolin-1 epithelial immunostaining patterns to stratify human breast cancer patients and predict the Caveolin-1 (P132L) mutation.
Cell cycle (Georgetown, Tex.) 2009;8(9):1396-401.
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2009: Mercier Isabelle; Casimiro Mathew C; Zhou Jie; Wang Chenguang; Plymire Christopher; Bryant Kelly G; Daumer Kristin M; Sotgia Federica; Bonuccelli Gloria; Witkiewicz Agnieszka K; Lin Justin; Tran Thai Hong; Milliman Janet; Frank Philippe G; Jasmin Jean-François; Rui Hallgeir; Pestell Richard G; Lisanti Michael P
Genetic ablation of caveolin-1 drives estrogen-hypersensitivity and the development of DCIS-like mammary lesions.
The American journal of pathology 2009;174(4):1172-90.
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2009: Sotgia Federica; Del Galdo Francesco; Casimiro Mathew C; Bonuccelli Gloria; Mercier Isabelle; Whitaker-Menezes Diana; Daumer Kristin M; Zhou Jie; Wang Chenguang; Katiyar Sanjay; Xu Huan; Bosco Emily; Quong Andrew A; Aronow Bruce; Witkiewicz Agnieszka K; Minetti Carlo; Frank Philippe G; Jimenez Sergio A; Knudsen Erik S; Pestell Richard G; Lisanti Michael P
Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts.
The American journal of pathology 2009;174(3):746-61.
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2009: Marmon Shana; Hinchey Joseph; Raine Cedric S; Lisanti Michael P
Chemokine transport and leukocyte extravasation through dermal microvasculature in the absence of caveolae.
Journal of dermatological science 2009;53(3):225-8.
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2009: Marmon Shana; Hinchey Joseph; Oh Philmo; Cammer Michael; de Almeida Cecilia J; Gunther Leslie; Raine Cedric S; Lisanti Michael P
Caveolin-1 expression determines the route of neutrophil extravasation through skin microvasculature.
The American journal of pathology 2009;174(2):684-92.
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2009: Sotgia Federica; Casimiro Mathew C; Bonuccelli Gloria; Liu Manran; Whitaker-Menezes Diana; Er Ozlem; Daumer Kristin M; Mercier Isabelle; Witkiewicz Agnieszka K; Minetti Carlo; Capozza Franco; Gormley Michael; Quong Andrew A; Rui Hallgeir; Frank Philippe G; Milliman Janet N; Knudsen Erik S; Zhou Jie; Wang Chenguang; Pestell Richard G; Lisanti Michael P
Loss of caveolin-3 induces a lactogenic microenvironment that is protective against mammary tumor formation.
The American journal of pathology 2009;174(2):613-29.
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2009: Frank Philippe G; Pavlides Stephanos; Lisanti Michael P
Caveolae and transcytosis in endothelial cells: role in atherosclerosis.
Cell and tissue research 2009;335(1):41-7.
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2008: Okamoto Takashi; Okamoto Lisa; Lisanti Michael P; Akishita Masahiro
Switch to oral hypoglycemic agent therapy from insulin injection in patients with type 2 diabetes.
Geriatrics & gerontology international 2008;8(4):218-26.
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2008: Del Galdo Francesco; Lisanti Michael P; Jimenez Sergio A
Caveolin-1, transforming growth factor-beta receptor internalization, and the pathogenesis of systemic sclerosis.
Current opinion in rheumatology 2008;20(6):713-9.
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2008: Witkiewicz Agnieszka K; Nguyen Katherine H; Dasgupta Abhijit; Kennedy Eugene P; Yeo Charles J; Lisanti Michael P; Brody Jonathan R
Co-expression of fatty acid synthase and caveolin-1 in pancreatic ductal adenocarcinoma: implications for tumor progression and clinical outcome.
Cell cycle (Georgetown, Tex.) 2008;7(19):3021-5.
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2008: Chen Jia; Capozza Franco; Wu An; Deangelis Tiziana; Sun Hongzhi; Lisanti Michael; Baserga Renato
Regulation of insulin receptor substrate-1 expression levels by caveolin-1.
Journal of cellular physiology 2008;217(1):281-9.
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2008: Nagajyothi Fnu; Desruisseaux Mahalia S; Thiruvur Niranjan; Weiss Louis M; Braunstein Vicki L; Albanese Chris; Teixeira Mauro M; de Almeida Cecilia J; Lisanti Michael P; Scherer Philipp E; Tanowitz Herbert B
Trypanosoma cruzi infection of cultured adipocytes results in an inflammatory phenotype.
Obesity (Silver Spring, Md.) 2008;16(9):1992-7.
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2008: Galdo Francesco Del; Sotgia Federica; de Almeida Cecilia J; Jasmin Jean-Francois; Musick Megan; Lisanti Michael P; Jiménez Sergio A
Decreased expression of caveolin 1 in patients with systemic sclerosis: Crucial role in the pathogenesis of tissue fibrosis.
Arthritis and rheumatism 2008;58(9):2854-65.
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2008: Frank Philippe G; Lisanti Michael P
ICAM-1: role in inflammation and in the regulation of vascular permeability.
American journal of physiology. Heart and circulatory physiology 2008;295(3):H926-H927.
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2008: Augustus Ayanna S; Buchanan Jonathan; Gutman Ellen; Rengo Giuseppe; Pestell Richard G; Fortina Paolo; Koch Walter J; Bensadoun Andre; Abel E Dale; Lisanti Michael P
Hearts lacking caveolin-1 develop hypertrophy with normal cardiac substrate metabolism.
Cell cycle (Georgetown, Tex.) 2008;7(16):2509-18.
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2008: Augustus Ayanna S; Buchanan Jonathan; Addya Sankar; Rengo Giuseppe; Pestell Richard G; Fortina Paolo; Koch Walter J; Bensadoun Andre; Abel E Dale; Lisanti Michael P
Substrate uptake and metabolism are preserved in hypertrophic caveolin-3 knockout hearts.
American journal of physiology. Heart and circulatory physiology 2008;295(2):H657-66.
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2008: Mercier Isabelle; Casimiro Mathew C; Wang Chenguang; Rosenberg Anne L; Quong Judy; Minkeu Alimatou; Allen Kathleen G; Danilo Christiane; Sotgia Federica; Bonuccelli Gloria; Jasmin Jean-François; Xu Huan; Bosco Emily; Aronow Bruce; Witkiewicz Agnieszka; Pestell Richard G; Knudsen Erik S; Lisanti Michael P
Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 downregulation and RB tumor suppressor functional inactivation: Implications for the response to hormonal therapy.
Cancer biology & therapy 2008;7(8):1212-25.
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2008: Assereto Stefania; Mastrototaro Mauro; Stringara Silvia; Gazzerro Elisabetta; Broda Paolo; Nicchia Grazia Paola; Svelto Maria; Bruno Claudio; Nigro Vincenzo; Lisanti M P; Frigeri Antonio; Minetti Carlo
Aquaporin-4 expression is severely reduced in human sarcoglycanopathies and dysferlinopathies.
Cell cycle (Georgetown, Tex.) 2008;7(14):2199-207.
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2008: Di Vizio Dolores; Adam Rosalyn M; Kim Jayoung; Kim Robert; Sotgia Federica; Williams Terence; Demichelis Francesca; Solomon Keith R; Loda Massimo; Rubin Mark A; Lisanti Michael P; Freeman Michael R
Caveolin-1 interacts with a lipid raft-associated population of fatty acid synthase.
Cell cycle (Georgetown, Tex.) 2008;7(14):2257-67.
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2008: Frank Philippe G; Pavlides Stephanos; Cheung Michelle W-C; Daumer Kristin; Lisanti Michael P
Role of caveolin-1 in the regulation of lipoprotein metabolism.
American journal of physiology. Cell physiology 2008;295(1):C242-8.
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2008: Kim Min; Wu Xiaofang; Song Insun; Fu Maofu; Chang Seo-Hee; Lisanti Michael P; Pestell Richard
Selective cytotoxicity of synthesized procyanidin 3-O-galloylepicatechin-4b, 8-3-O-galloylcatechin to human cancer cells.
Cell cycle (Georgetown, Tex.) 2008;7(11):1648-57.
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2008: Abdulghani Junaid; Gu Lei; Dagvadorj Ayush; Lutz Jacqueline; Leiby Benjamin; Bonuccelli Gloria; Lisanti Michael P; Zellweger Tobias; Alanen Kalle; Mirtti Tuomas; Visakorpi Tapio; Bubendorf Lukas; Nevalainen Marja T
Stat3 promotes metastatic progression of prostate cancer.
The American journal of pathology 2008;172(6):1717-28.
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2008: Mercier Isabelle; Vuolo Magalis; Jasmin Jean-Francois; Medina Christina M; Williams Mark; Mariadason John M; Qian Hong; Xue Xiaonan; Pestell Richard G; Lisanti Michael P; Kitsis Richard N
ARC (apoptosis repressor with caspase recruitment domain) is a novel marker of human colon cancer.
Cell cycle (Georgetown, Tex.) 2008;7(11):1640-7.
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2008: Wu Kongming; Katiyar Sanjay; Li Anping; Liu Manran; Ju Xiaoming; Popov Vladimir M; Jiao Xuanmao; Lisanti Michael P; Casola Antonella; Pestell Richard G
Dachshund inhibits oncogene-induced breast cancer cellular migration and invasion through suppression of interleukin-8.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(19):6924-9.
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2008: Mukherjee Shankar; Nagajyothi Fnu; Mukhopadhyay Aparna; Machado Fabiana S; Belbin Thomas J; Campos de Carvalho Antonio; Guan Fangxia; Albanese Chris; Jelicks Linda A; Lisanti Michael P; Silva Joao S; Spray David C; Weiss Louis M; Tanowitz Herbert B
Alterations in myocardial gene expression associated with experimental Trypanosoma cruzi infection.
Genomics 2008;91(5):423-32.
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2008: Jiao Xuanmao; Katiyar Sanjay; Liu Manran; Mueller Susette C; Lisanti Michael P; Li Anping; Pestell Timothy G; Wu Kongming; Ju Xiaoming; Li Zhiping; Wagner Erwin F; Takeya Tatsuo; Wang Chenguang; Pestell Richard G
Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase.
Molecular biology of the cell 2008;19(4):1378-90.
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2008: Gioiosa Laura; Raggi Carla; Ricceri Laura; Jasmin Jean-François; Frank Philippe G; Capozza Franco; Lisanti Michael P; Alleva Enrico; Sargiacomo Massimo; Laviola Giovanni
Altered emotionality, spatial memory and cholinergic function in caveolin-1 knock-out mice.
Behavioural brain research 2008;188(2):255-62.
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2008: Traverso Monica; Gazzerro Elisabetta; Assereto Stefania; Sotgia Federica; Biancheri Roberta; Stringara Silvia; Giberti Laura; Pedemonte Marina; Wang Xiabo; Scapolan Sara; Pasquini Elisabetta; Donati Maria A; Zara Federico; Lisanti Michael P; Bruno Claudio; Minetti Carlo
Caveolin-3 T78M and T78K missense mutations lead to different phenotypes in vivo and in vitro.
Laboratory investigation; a journal of technical methods and pathology 2008;88(3):275-83.
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2008: Rao Mahadev; Casimiro Mathew C; Lisanti Michael P; D'Amico Mark; Wang Chenguang; Shirley L Andrew; Leader Jennifer E; Liu Manran; Stallcup Michael; Engel Daniel A; Murphy Daniel J; Pestell Richard G
Inhibition of cyclin D1 gene transcription by Brg-1.
Cell cycle (Georgetown, Tex.) 2008;7(5):647-55.
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2008: Bouzahzah Boumediene; Yurchenko Vyacheslav; Nagajyothi Fnu; Hulit James; Sadofsky Moshe; Braunstein Vicki L; Mukherjee Shankar; Weiss Hannah; Machado Fabiana S; Pestell Richard G; Lisanti Michael P; Tanowitz Herbert B; Albanese Chris
Regulation of host cell cyclin D1 by Trypanosoma cruzi in myoblasts.
Cell cycle (Georgetown, Tex.) 2008;7(4):500-3.
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2007: Di Vizio Dolores; Sotgia Federica; Williams Terence M; Hassan Ghada S; Capozza Franco; Frank Philippe G; Pestell Richard G; Loda Massimo; Freeman Michael R; Lisanti Michael P
Caveolin-1 is required for the upregulation of fatty acid synthase (FASN), a tumor promoter, during prostate cancer progression.
Cancer biology & therapy 2007;6(8):1263-8.
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2007: Biancheri Roberta; Zara Federico; Bruno Claudio; Rossi Andrea; Bordo Laura; Gazzerro Elisabetta; Sotgia Federica; Pedemonte Marina; Scapolan Sara; Bado Massimo; Uziel Graziella; Bugiani Marianna; Lamba Laura Doria; Costa Valeria; Schenone Angelo; Rozemuller Annemieke J M; Tortori-Donati Paolo; Lisanti Michael P; van der Knaap Marjo S; Minetti Carlo
Phenotypic characterization of hypomyelination and congenital cataract.
Annals of neurology 2007;62(2):121-7.
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2007: Lai Edwin W; Rodriguez Olga C; Aventian Maral; Cromelin Caroline; Fricke Stanley T; Martiniova Lucia; Lubensky Irina A; Lisanti Michael P; Picard Kristen L; Powers James F; Tischler Arthur S; Pacak Karel; Albanese Chris
ErbB-2 induces bilateral adrenal pheochromocytoma formation in mice.
Cell cycle (Georgetown, Tex.) 2007;6(15):1946-50.
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2007: Bonuccelli Gloria; Sotgia Federica; Capozza Franco; Gazzerro Elisabetta; Minetti Carlo; Lisanti Michael P
Localized treatment with a novel FDA-approved proteasome inhibitor blocks the degradation of dystrophin and dystrophin-associated proteins in mdx mice.
Cell cycle (Georgetown, Tex.) 2007;6(10):1242-8.
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2007: Ju Xiaoming; Katiyar Sanjay; Wang Chenguang; Liu Manran; Jiao Xuanmao; Li Shengwen; Zhou Jie; Turner Jacob; Lisanti Michael P; Russell Robert G; Mueller Susette C; Ojeifo John; Chen William S; Hay Nissim; Pestell Richard G
Akt1 governs breast cancer progression in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(18):7438-43.
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2007: Hulit James; Suyama Kimita; Chung Su; Keren Rinat; Agiostratidou Georgia; Shan Weisong; Dong Xinyuan; Williams Terence M; Lisanti Michael P; Knudsen Karen; Hazan Rachel B
N-cadherin signaling potentiates mammary tumor metastasis via enhanced extracellular signal-regulated kinase activation.
Cancer research 2007;67(7):3106-16.
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2007: Muehlbauer Stefan M; Evering Teresa H; Bonuccelli Gloria; Squires Raynal C; Ashton Anthony W; Porcelli Steven A; Lisanti Michael P; Brojatsch Jürgen
Anthrax lethal toxin kills macrophages in a strain-specific manner by apoptosis or caspase-1-mediated necrosis.
Cell cycle (Georgetown, Tex.) 2007;6(6):758-66.
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2007: Medina Freddy A; Cohen Alex W; de Almeida Cecilia J; Nagajyothi Fnu; Braunstein Vicki L; Teixeira Mauro Martins; Tanowitz Herbert B; Lisanti Michael P
Immune dysfunction in caveolin-1 null mice following infection with Trypanosoma cruzi (Tulahuen strain).
Microbes and infection / Institut Pasteur 2007;9(3):325-33.
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2007: Jasmin Jean-François; Malhotra Samit; Singh Dhallu Manjeet; Mercier Isabelle; Rosenbaum Daniel M; Lisanti Michael P
Caveolin-1 deficiency increases cerebral ischemic injury.
Circulation research 2007;100(5):721-9.
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2007: Wu Kongming; Liu Manran; Li Anping; Donninger Howard; Rao Mahadev; Jiao Xuanmao; Lisanti Michael P; Cvekl Ales; Birrer Michael; Pestell Richard G
Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth.
Molecular biology of the cell 2007;18(3):755-67.
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2007: Katiyar Sanjay; Jiao Xuanmao; Wagner Erwin; Lisanti Michael P; Pestell Richard G
Somatic excision demonstrates that c-Jun induces cellular migration and invasion through induction of stem cell factor.
Molecular and cellular biology 2007;27(4):1356-69.
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2007: Frank Philippe G; Lisanti Michael P
Caveolin-1 and liver regeneration: role in proliferation and lipogenesis.
Cell cycle (Georgetown, Tex.) 2007;6(2):115-6.
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2007: Fang Kai; Fu Wei; Beardsley Andrew R; Sun Xinghui; Lisanti Michael P; Liu Jun
Overexpression of caveolin-1 inhibits endothelial cell proliferation by arresting the cell cycle at G0/G1 phase.
Cell cycle (Georgetown, Tex.) 2007;6(2):199-204.
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2007: Schubert William; Sotgia Federica; Cohen Alex W; Capozza Franco; Bonuccelli Gloria; Bruno Claudio; Minetti Carlo; Bonilla Eduardo; Dimauro Salvatore; Lisanti Michael P
Caveolin-1(-/-)- and caveolin-2(-/-)-deficient mice both display numerous skeletal muscle abnormalities, with tubular aggregate formation.
The American journal of pathology 2007;170(1):316-33.
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2007: Frank Philippe G; Hassan Ghada S; Rodriguez-Feo Juan A; Lisanti Michael P
Caveolae and caveolin-1: novel potential targets for the treatment of cardiovascular disease.
Current pharmaceutical design 2007;13(17):1761-9.
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2006: Frank Philippe G; Lisanti Michael P
Zebrafish as a novel model system to study the function of caveolae and caveolin-1 in organismal biology.
The American journal of pathology 2006;169(6):1910-2.
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2006: Medina Freddy A; de Almeida Cecilia J; Dew Elliott; Li Jiangwei; Bonuccelli Gloria; Williams Terence M; Cohen Alex W; Pestell Richard G; Frank Philippe G; Tanowitz Herbert B; Lisanti Michael P
Caveolin-1-deficient mice show defects in innate immunity and inflammatory immune response during Salmonella enterica serovar Typhimurium infection.
Infection and immunity 2006;74(12):6665-74.
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2006: Sotgia Federica; Rui Hallgeir; Bonuccelli Gloria; Mercier Isabelle; Pestell Richard G; Lisanti Michael P
Caveolin-1, mammary stem cells, and estrogen-dependent breast cancers.
Cancer research 2006;66(22):10647-51.
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2006: Williams Terence M; Sotgia Federica; Lee Hyangkyu; Hassan Ghada; Di Vizio Dolores; Bonuccelli Gloria; Capozza Franco; Mercier Isabelle; Rui Hallgeir; Pestell Richard G; Lisanti Michael P
Stromal and epithelial caveolin-1 both confer a protective effect against mammary hyperplasia and tumorigenesis: Caveolin-1 antagonizes cyclin D1 function in mammary epithelial cells.
The American journal of pathology 2006;169(5):1784-801.
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2006: Bouzahzah Boumediene; Nagajyothi Fnu; Desruisseaux Mahalia S; Krishnamachary Mohan; Factor Stephen M; Cohen Alex W; Lisanti Michael P; Petkova Stefka B; Pestell Richard G; Wittner Murray; Mukherjee Shankar; Weiss Louis M; Jelicks Linda A; Albanese Chris; Tanowitz Herbert B
Cell cycle regulatory proteins in the liver in murine Trypanosoma cruzi infection.
Cell cycle (Georgetown, Tex.) 2006;5(20):2396-400.
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2006: Li Zhiping; Jiao Xuanmao; Wang Chenguang; Ju Xiaoming; Lu Yinan; Yuan Liangping; Lisanti Michael P; Katiyar Sanjay; Pestell Richard G
Cyclin D1 induction of cellular migration requires p27(KIP1).
Cancer research 2006;66(20):9986-94.
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2006: Wu Kongming; Li Anping; Rao Mahadev; Liu Manran; Dailey Vernon; Yang Ying; Di Vizio Dolores; Wang Chenguang; Lisanti Michael P; Sauter Guido; Russell Robert G; Cvekl Ales; Pestell Richard G
DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth.
Molecular and cellular biology 2006;26(19):7116-29.
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2006: Zara Federico; Biancheri Roberta; Bruno Claudio; Bordo Laura; Assereto Stefania; Gazzerro Elisabetta; Sotgia Federica; Wang Xiao Bo; Gianotti Stefania; Stringara Silvia; Pedemonte Marina; Uziel Graziella; Rossi Andrea; Schenone Angelo; Tortori-Donati Paolo; van der Knaap Marjo S; Lisanti Michael P; Minetti Carlo
Deficiency of hyccin, a newly identified membrane protein, causes hypomyelination and congenital cataract.
Nature genetics 2006;38(10):1111-3.
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2006: Hnasko Robert; Carter John Mark; Medina Freddy; Frank Philippe G; Lisanti Michael P
PV-1 labels trans-cellular openings in mouse endothelial cells and is negatively regulated by VEGF.
Cell cycle (Georgetown, Tex.) 2006;5(17):2021-8.
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2006: Hnasko Robert; Frank Philippe G; Ben-Jonathan Nira; Lisanti Michael P
PV-1 is negatively regulated by VEGF in the lung of caveolin-1, but not caveolin-2, null mice.
Cell cycle (Georgetown, Tex.) 2006;5(17):2012-20.
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2006: Hulit James; Lee Richard J; Li Zhiping; Wang Chenguang; Katiyar Sanjay; Yang Jianguo; Quong Andrew A; Wu Kongming; Albanese Chris; Russell Robert; Di Vizio Dolores; Koff Andrew; Thummala Saiinder; Zhang Hui; Harrell Jennifer; Sun Hong; Muller William J; Inghirami Giorgio; Lisanti Michael P; Pestell Richard G
p27Kip1 repression of ErbB2-induced mammary tumor growth in transgenic mice involves Skp2 and Wnt/beta-catenin signaling.
Cancer research 2006;66(17):8529-41.
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2006: Jasmin Jean-François; Mercier Isabelle; Dupuis Jocelyn; Tanowitz Herbert B; Lisanti Michael P
Short-term administration of a cell-permeable caveolin-1 peptide prevents the development of monocrotaline-induced pulmonary hypertension and right ventricular hypertrophy.
Circulation 2006;114(9):912-20.
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2006: Medina Freddy A; Williams Terence M; Sotgia Federica; Tanowitz Herbert B; Lisanti Michael P
A novel role for caveolin-1 in B lymphocyte function and the development of thymus-independent immune responses.
Cell cycle (Georgetown, Tex.) 2006;5(16):1865-71.
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2006: Frank Philippe G; Cheung Michelle W-C; Pavlides Stephanos; Llaverias Gemma; Park David S; Lisanti Michael P
Caveolin-1 and regulation of cellular cholesterol homeostasis.
American journal of physiology. Heart and circulatory physiology 2006;291(2):H677-86.
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2006: Li Tianhong; Sotgia Federica; Vuolo Magalis A; Li Maomi; Yang Wan Cai; Pestell Richard G; Sparano Joseph A; Lisanti Michael P
Caveolin-1 mutations in human breast cancer: functional association with estrogen receptor alpha-positive status.
The American journal of pathology 2006;168(6):1998-2013.
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2006: Frank Philippe G; Lisanti Michael P
Defining lipid raft structure and function with proximity imaging.
American journal of physiology. Heart and circulatory physiology 2006;290(6):H2165-6.
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2006: Hassan Ghada S; Williams Terence M; Frank Philippe G; Lisanti Michael P
Caveolin-1-deficient aortic smooth muscle cells show cell autonomous abnormalities in proliferation, migration, and endothelin-based signal transduction.
American journal of physiology. Heart and circulatory physiology 2006;290(6):H2393-401.
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2006: Frank Philippe G; Lisanti Michael P
Role of caveolin-1 in the regulation of the vascular shear stress response.
The Journal of clinical investigation 2006;116(5):1222-5.
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2006: Jasmin Jean-François; Mercier Isabelle; Sotgia Federica; Lisanti Michael P
SOCS proteins and caveolin-1 as negative regulators of endocrine signaling.
Trends in endocrinology and metabolism: TEM 2006;17(4):150-8.
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2006: Khan Elaine M; Heidinger Jill M; Levy Michal; Lisanti Michael P; Ravid Tommer; Goldkorn Tzipora
Epidermal growth factor receptor exposed to oxidative stress undergoes Src- and caveolin-1-dependent perinuclear trafficking.
The Journal of biological chemistry 2006;281(20):14486-93.
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2006: Sotgia Federica; Schubert William; Pestell Richard G; Lisanti Michael P
Genetic ablation of caveolin-1 in mammary epithelial cells increases milk production and hyper-activates STAT5a signaling.
Cancer biology & therapy 2006;5(3):292-7.
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2006: Selvaraj Vimal; Asano Atsushi; Buttke Danielle E; McElwee John L; Nelson Jacquelyn L; Wolff Collin A; Merdiushev Tanya; Fornés Miguel W; Cohen Alex W; Lisanti Michael P; Rothblat George H; Kopf Gregory S; Travis Alexander J
Segregation of micron-scale membrane sub-domains in live murine sperm.
Journal of cellular physiology 2006;206(3):636-46.
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2006: Assereto Stefania; Stringara Silvia; Sotgia Federica; Bonuccelli Gloria; Broccolini Aldobrando; Pedemonte Marina; Traverso Monica; Biancheri Roberta; Zara Federico; Bruno Claudio; Lisanti Michael P; Minetti Carlo
Pharmacological rescue of the dystrophin-glycoprotein complex in Duchenne and Becker skeletal muscle explants by proteasome inhibitor treatment.
American journal of physiology. Cell physiology 2006;290(2):C577-82.
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2006: Sotgia Federica; Williams Terence M; Schubert William; Medina Freddy; Minetti Carlo; Pestell Richard G; Lisanti Michael P
Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness.
The American journal of pathology 2006;168(1):292-309.
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2006: Lee Hyangkyu; Xie Laiping; Luo Yong; Lee Seung-Yub; Lawrence David S; Wang Xiao Bo; Sotgia Federica; Lisanti Michael P; Zhang Zhong-Yin
Identification of phosphocaveolin-1 as a novel protein tyrosine phosphatase 1B substrate.
Biochemistry 2006;45(1):234-40.
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2006: Hassan Ghada S; Mukherjee Shankar; Nagajyothi Fnu; Weiss Louis M; Petkova Stefka B; de Almeida Cecilia J; Huang Huan; Desruisseaux Mahalia S; Bouzahzah Boumediene; Pestell Richard G; Albanese Chris; Christ George J; Lisanti Michael P; Tanowitz Herbert B
Trypanosoma cruzi infection induces proliferation of vascular smooth muscle cells.
Infection and immunity 2006;74(1):152-9.
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2006: Alileche Abdelkrim; Squires Raynal C; Muehlbauer Stefan M; Lisanti Michael P; Brojatsch Jürgen
Mitochondrial impairment is a critical event in anthrax lethal toxin-induced cytolysis of murine macrophages.
Cell cycle (Georgetown, Tex.) 2006;5(1):100-6.
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2006: Rodriguez Olga; Fricke Stanley; Chien Christopher; Dettin Luis; VanMeter John; Shapiro Erik; Dai Hai-Ning; Casimiro Mathew; Ileva Lilia; Dagata John; Johnson Michael D; Lisanti Michael P; Koretsky Alan; Albanese Chris
Contrast-enhanced in vivo imaging of breast and prostate cancer cells by MRI.
Cell cycle (Georgetown, Tex.) 2006;5(1):113-9.
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2006: Nagajyothi Fnu; Desruisseaux Mahalia; Bouzahzah Boumediene; Weiss Louis M; Andrade Daniele dos Santos; Factor Stephen M; Scherer Philipp E; Albanese Chris; Lisanti Michael P; Tanowitz Herbert B
Cyclin and caveolin expression in an acute model of murine Chagasic myocarditis.
Cell cycle (Georgetown, Tex.) 2006;5(1):107-12.
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2005: Li Jiangwei; Hassan Ghada S; Williams Terence M; Minetti Carlo; Pestell Richard G; Tanowitz Herbert B; Frank Philippe G; Sotgia Federica; Lisanti Michael P
Loss of caveolin-1 causes the hyper-proliferation of intestinal crypt stem cells, with increased sensitivity to whole body gamma-radiation.
Cell cycle (Georgetown, Tex.) 2005;4(12):1817-25.
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2005: Sotgia Federica; Williams Terence M; Cohen Alex W; Minetti Carlo; Pestell Richard G; Lisanti Michael P
Caveolin-1-deficient mice have an increased mammary stem cell population with upregulation of Wnt/beta-catenin signaling.
Cell cycle (Georgetown, Tex.) 2005;4(12):1808-16.
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2005: Li Jiangwei; Scherl Alexis; Medina Freddy; Frank Philippe G; Kitsis Richard N; Tanowitz Herbert B; Sotgia Federica; Lisanti Michael P
Impaired phagocytosis in caveolin-1 deficient macrophages.
Cell cycle (Georgetown, Tex.) 2005;4(11):1599-607.
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2005: Fine Samson W; Lisanti Michael P; Argani Pedram; Li Maomi
Caveolin-3 is a sensitive and specific marker for rhabdomyosarcoma.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2005;13(3):231-6.
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2005: Wang Chenguang; Fan Saijun; Li Zhiping; Fu Maofu; Rao Mahadev; Ma Yongxian; Lisanti Michael P; Albanese Chris; Katzenellenbogen Benita S; Kushner Peter J; Weber Barbara; Rosen Eliot M; Pestell Richard G
Cyclin D1 antagonizes BRCA1 repression of estrogen receptor alpha activity.
Cancer research 2005;65(15):6557-67.
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2005: Fu Maofu; Wang Chenguang; Rao Mahadev; Wu Xiaofang; Bouras Toula; Zhang Xueping; Li Zhiping; Jiao Xuanmao; Yang Jianguo; Li Anping; Perkins Neil D; Thimmapaya Bayar; Kung Andrew L; Munoz Alberto; Giordano Antonio; Lisanti Michael P; Pestell Richard G
Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism.
The Journal of biological chemistry 2005;280(33):29728-42.
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2005: Williams Terence M; Hassan Ghada S; Li Jiangwei; Cohen Alex W; Medina Freddy; Frank Philippe G; Pestell Richard G; Di Vizio Dolores; Loda Massimo; Lisanti Michael P
Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice.
The Journal of biological chemistry 2005;280(26):25134-45.
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2005: Combs Terry P; Nagajyothi; Mukherjee Shankar; de Almeida Cecilia J G; Jelicks Linda A; Schubert William; Lin Ying; Jayabalan David S; Zhao Dazhi; Braunstein Vicki L; Landskroner-Eiger Shira; Cordero Aisha; Factor Stephen M; Weiss Louis M; Lisanti Michael P; Tanowitz Herbert B; Scherer Philipp E
The adipocyte as an important target cell for Trypanosoma cruzi infection.
The Journal of biological chemistry 2005;280(25):24085-94.
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2005: Capozza Franco; Combs Terry P; Cohen Alex W; Cho You-Ree; Park So-Young; Schubert William; Williams Terence M; Brasaemle Dawn L; Jelicks Linda A; Scherer Philipp E; Kim Jason K; Lisanti Michael P
Caveolin-3 knockout mice show increased adiposity and whole body insulin resistance, with ligand-induced insulin receptor instability in skeletal muscle.
American journal of physiology. Cell physiology 2005;288(6):C1317-31.
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2005: Bonuccelli Gloria; Sotgia Federica; Frank Philippe G; Williams Terence M; de Almeida Cecilia J; Tanowitz Herbert B; Scherer Philipp E; Hotchkiss Kylie A; Terman Bruce I; Rollman Brent; Alileche Abdelkrim; Brojatsch Jürgen; Lisanti Michael P
ATR/TEM8 is highly expressed in epithelial cells lining Bacillus anthracis' three sites of entry: implications for the pathogenesis of anthrax infection.
American journal of physiology. Cell physiology 2005;288(6):C1402-10.
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2005: Iyengar Puneeth; Espina Virginia; Williams Terence W; Lin Ying; Berry David; Jelicks Linda A; Lee Hyangkyu; Temple Karla; Graves Reed; Pollard Jeffrey; Chopra Neeru; Russell Robert G; Sasisekharan Ram; Trock Bruce J; Lippman Marc; Calvert Valerie S; Petricoin Emanuel F; Liotta Lance; Dadachova Ekaterina; Pestell Richard G; Lisanti Michael P; Bonaldo Paolo; Scherer Philipp E
Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment.
The Journal of clinical investigation 2005;115(5):1163-76.
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2005: Roy Suheeta; Hyogo Hideyuki; Yadav Suresh K; Wu Michele K; Jelicks Linda A; Locker Joseph D; Frank Philippe G; Lisanti Michael P; Silver David L; Cohen David E
A biphasic response of hepatobiliary cholesterol metabolism to dietary fat at the onset of obesity in the mouse.
Hepatology (Baltimore, Md.) 2005;41(4):887-95.
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2005: Hotchkiss Kylie A; Basile Cheryl M; Spring Simone C; Bonuccelli Gloria; Lisanti Michael P; Terman Bruce I
TEM8 expression stimulates endothelial cell adhesion and migration by regulating cell-matrix interactions on collagen.
Experimental cell research 2005;305(1):133-44.
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2005: Cohen Alex W; Schubert William; Brasaemle Dawn L; Scherer Philipp E; Lisanti Michael P
Caveolin-1 expression is essential for proper nonshivering thermogenesis in brown adipose tissue.
Diabetes 2005;54(3):679-86.
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2005: Williams Terence M; Lisanti Michael P
Caveolin-1 in oncogenic transformation, cancer, and metastasis.
American journal of physiology. Cell physiology 2005;288(3):C494-506.
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2005: Capozza Franco; Cohen Alex W; Cheung Michelle W-C; Sotgia Federica; Schubert William; Battista Michela; Lee Hyangkyu; Frank Philippe G; Lisanti Michael P
Muscle-specific interaction of caveolin isoforms: differential complex formation between caveolins in fibroblastic vs. muscle cells.
American journal of physiology. Cell physiology 2005;288(3):C677-91.
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2005: De Souza Andrea Pereira; Cohen Alex W; Park David S; Woodman Scott E; Tang Baiyu; Gutstein David E; Factor Stephen M; Tanowitz Herbert B; Lisanti Michael P; Jelicks Linda A
MR imaging of caveolin gene-specific alterations in right ventricular wall thickness.
Magnetic resonance imaging 2005;23(1):61-8.
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2004: Williams Terence M; Medina Freddy; Badano Ines; Hazan Rachel B; Hutchinson John; Muller William J; Chopra Neeru G; Scherer Philipp E; Pestell Richard G; Lisanti Michael P
Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion.
The Journal of biological chemistry 2004;279(49):51630-46.
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2004: Berg Anders H; Lin Ying; Lisanti Michael P; Scherer Philipp E
Adipocyte differentiation induces dynamic changes in NF-kappaB expression and activity.
American journal of physiology. Endocrinology and metabolism 2004;287(6):E1178-88.
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2004: Wang Xiao Bo; Lee Hyangkyu; Capozza Franco; Marmon Shana; Sotgia Federica; Brooks James W; Campos-Gonzalez Roberto; Lisanti Michael P
Tyrosine phosphorylation of caveolin-2 at residue 27: differences in the spatial and temporal behavior of phospho-Cav-2 (pY19 and pY27).
Biochemistry 2004;43(43):13694-706.
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2004: Bouras Toula; Lisanti Michael P; Pestell Richard G
Caveolin-1 in breast cancer.
Cancer biology & therapy 2004;3(10):931-41.
-
2004: Cohen Alex W; Hnasko Robert; Schubert William; Lisanti Michael P
Role of caveolae and caveolins in health and disease.
Physiological reviews 2004;84(4):1341-79.
-
2004: Frank Philippe G; Lisanti Michael P
Caveolin-1 and caveolae in atherosclerosis: differential roles in fatty streak formation and neointimal hyperplasia.
Current opinion in lipidology 2004;15(5):523-9.
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2004: Subramanian Vidya; Rothenberg Alexis; Gomez Carlos; Cohen Alex W; Garcia Anne; Bhattacharyya Sucharita; Shapiro Lawrence; Dolios Georgia; Wang Rong; Lisanti Michael P; Brasaemle Dawn L
Perilipin A mediates the reversible binding of CGI-58 to lipid droplets in 3T3-L1 adipocytes.
The Journal of biological chemistry 2004;279(40):42062-71.
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2004: Mukherjee Shankar; Huang Huan; Petkova Stefka B; Albanese Chris; Pestell Richard G; Braunstein Vicki L; Christ George J; Wittner Murray; Lisanti Michael P; Berman Joan W; Weiss Louis M; Tanowitz Herbert B
Trypanosoma cruzi infection activates extracellular signal-regulated kinase in cultured endothelial and smooth muscle cells.
Infection and immunity 2004;72(9):5274-82.
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2004: Jasmin Jean-François; Mercier Isabelle; Hnasko Robert; Cheung Michelle W-C; Tanowitz Herbert B; Dupuis Jocelyn; Lisanti Michael P
Lung remodeling and pulmonary hypertension after myocardial infarction: pathogenic role of reduced caveolin expression.
Cardiovascular research 2004;63(4):747-55.
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2004: Hassan Ghada S; Jasmin Jean-François; Schubert William; Frank Philippe G; Lisanti Michael P
Caveolin-1 deficiency stimulates neointima formation during vascular injury.
Biochemistry 2004;43(26):8312-21.
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2004: Williams Terence M; Lee Hyangkyu; Cheung Michelle W-C; Cohen Alex W; Razani Babak; Iyengar Puneeth; Scherer Philipp E; Pestell Richard G; Lisanti Michael P
Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia.
The Journal of biological chemistry 2004;279(23):24745-56.
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2004: Cohen Alex W; Razani Babak; Schubert William; Williams Terence M; Wang Xiao Bo; Iyengar Puneeth; Brasaemle Dawn L; Scherer Philipp E; Lisanti Michael P
Role of caveolin-1 in the modulation of lipolysis and lipid droplet formation.
Diabetes 2004;53(5):1261-70.
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2004: Woodman S E; Sotgia F; Galbiati F; Minetti C; Lisanti M P
Caveolinopathies: mutations in caveolin-3 cause four distinct autosomal dominant muscle diseases.
Neurology 2004;62(4):538-43.
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2004: Woodman Scott E; Cheung Michelle W-C; Tarr Moses; North Amanda C; Schubert William; Lagaud Guy; Marks Carolyn B; Russell Robert G; Hassan Ghada S; Factor Stephen M; Christ George J; Lisanti Michael P
Urogenital alterations in aged male caveolin-1 knockout mice.
The Journal of urology 2004;171(2 Pt 1):950-7.
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2004: Frank Philippe G; Lee Hyangkyu; Park David S; Tandon Narendra N; Scherer Phillip E; Lisanti Michael P
Genetic ablation of caveolin-1 confers protection against atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(1):98-105.
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2004: Williams Terence M; Lisanti Michael P
The Caveolin genes: from cell biology to medicine.
Annals of medicine 2004;36(8):584-95.
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2004: Williams Terence M; Lisanti Michael P
The caveolin proteins.
Genome biology 2004;5(3):214.
-
2003: Hnasko Robert; Lisanti Michael P
The biology of caveolae: lessons from caveolin knockout mice and implications for human disease.
Molecular interventions 2003;3(8):445-64.
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2003: Park David S; Cohen Alex W; Frank Philippe G; Razani Babak; Lee Hyangkyu; Williams Terence M; Chandra Madhulika; Shirani Jamshid; De Souza Andrea P; Tang Baiyu; Jelicks Linda A; Factor Stephen M; Weiss Louis M; Tanowitz Herbert B; Lisanti Michael P
Caveolin-1 null (-/-) mice show dramatic reductions in life span.
Biochemistry 2003;42(51):15124-31.
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2003: Sotgia Federica; Bonuccelli Gloria; Minetti Carlo; Woodman Scott E; Capozza Franco; Kemp Robert G; Scherer Philipp E; Lisanti Michael P
Phosphofructokinase muscle-specific isoform requires caveolin-3 expression for plasma membrane recruitment and caveolar targeting: implications for the pathogenesis of caveolin-related muscle diseases.
The American journal of pathology 2003;163(6):2619-34.
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2003: Cohen Alex W; Combs Terry P; Scherer Philipp E; Lisanti Michael P
Role of caveolin and caveolae in insulin signaling and diabetes.
American journal of physiology. Endocrinology and metabolism 2003;285(6):E1151-60.
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2003: Wu Kongming; Yang Ying; Wang Chenguang; Davoli Maria A; D'Amico Mark; Li Anping; Cveklova Kveta; Kozmik Zbynek; Lisanti Michael P; Russell Robert G; Cvekl Ales; Pestell Richard G
DACH1 inhibits transforming growth factor-beta signaling through binding Smad4.
The Journal of biological chemistry 2003;278(51):51673-84.
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2003: Aravamudan Bharathi; Volonte Daniela; Ramani Ravi; Gursoy Erdal; Lisanti Michael P; London Barry; Galbiati Ferruccio
Transgenic overexpression of caveolin-3 in the heart induces a cardiomyopathic phenotype.
Human molecular genetics 2003;12(21):2777-88.
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2003: Sotgia Federica; Woodman Scott E; Bonuccelli Gloria; Capozza Franco; Minetti Carlo; Scherer Philipp E; Lisanti Michael P
Phenotypic behavior of caveolin-3 R26Q, a mutant associated with hyperCKemia, distal myopathy, and rippling muscle disease.
American journal of physiology. Cell physiology 2003;285(5):C1150-60.
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2003: Bonuccelli Gloria; Sotgia Federica; Schubert William; Park David S; Frank Philippe G; Woodman Scott E; Insabato Luigi; Cammer Michael; Minetti Carlo; Lisanti Michael P
Proteasome inhibitor (MG-132) treatment of mdx mice rescues the expression and membrane localization of dystrophin and dystrophin-associated proteins.
The American journal of pathology 2003;163(4):1663-75.
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2003: Iyengar Puneeth; Combs Terry P; Shah Shalin J; Gouon-Evans Valérie; Pollard Jeffrey W; Albanese Chris; Flanagan Louise; Tenniswood Martin P; Guha Chandan; Lisanti Michael P; Pestell Richard G; Scherer Philipp E
Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization.
Oncogene 2003;22(41):6408-23.
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2003: Fong Andrew; Garcia Ediberto; Gwynn Lucas; Lisanti Michael P; Fazzari Melissa J; Li Maomi
Expression of caveolin-1 and caveolin-2 in urothelial carcinoma of the urinary bladder correlates with tumor grade and squamous differentiation.
American journal of clinical pathology 2003;120(1):93-100.
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2003: Frank Philippe G; Woodman Scott E; Park David S; Lisanti Michael P
Caveolin, caveolae, and endothelial cell function.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(7):1161-8.
-
2003: Cohen Alex W; Razani Babak; Wang Xiao Bo; Combs Terry P; Williams Terence M; Scherer Philipp E; Lisanti Michael P
Caveolin-1-deficient mice show insulin resistance and defective insulin receptor protein expression in adipose tissue.
American journal of physiology. Cell physiology 2003;285(1):C222-35.
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2003: Schubert William; Yang Xiao Yong; Yang Teddy T C; Factor Stephen M; Lisanti Michael P; Molkentin Jeffery D; Rincon Mercedes; Chow Chi-Wing
Requirement of transcription factor NFAT in developing atrial myocardium.
The Journal of cell biology 2003;161(5):861-74.
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2003: Sotgia Federica; Bonuccelli Gloria; Bedford Mark; Brancaccio Andrea; Mayer Ulrike; Wilson Mark T; Campos-Gonzalez Roberto; Brooks James W; Sudol Marius; Lisanti Michael P
Localization of phospho-beta-dystroglycan (pY892) to an intracellular vesicular compartment in cultured cells and skeletal muscle fibers in vivo.
Biochemistry 2003;42(23):7110-23.
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2003: Woodman Scott E; Ashton Anthony W; Schubert William; Lee Hyangkyu; Williams Terence M; Medina Freddy A; Wyckoff Jeffrey B; Combs Terry P; Lisanti Michael P
Caveolin-1 knockout mice show an impaired angiogenic response to exogenous stimuli.
The American journal of pathology 2003;162(6):2059-68.
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2003: Capozza Franco; Williams Terence M; Schubert William; McClain Steve; Bouzahzah Boumediene; Sotgia Federica; Lisanti Michael P
Absence of caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation.
The American journal of pathology 2003;162(6):2029-39.
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2003: Huang Huan; Petkova Stefka B; Cohen Alex W; Bouzahzah Boumediene; Chan John; Zhou Jian-nian; Factor Stephen M; Weiss Louis M; Krishnamachary Mohan; Mukherjee Shankar; Wittner Murray; Kitsis Richard N; Pestell Richard G; Lisanti Michael P; Albanese Chris; Tanowitz Herbert B
Activation of transcription factors AP-1 and NF-kappa B in murine Chagasic myocarditis.
Infection and immunity 2003;71(5):2859-67.
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2003: Williams Terence M; Cheung Michelle W-C; Park David S; Razani Babak; Cohen Alex W; Muller William J; Di Vizio Dolores; Chopra Neeru G; Pestell Richard G; Lisanti Michael P
Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice.
Molecular biology of the cell 2003;14(3):1027-42.
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2003: Cohen Alex W; Park David S; Woodman Scott E; Williams Terrence M; Chandra Madhulika; Shirani Jamshid; Pereira de Souza Andrea; Kitsis Richard N; Russell Robert G; Weiss Louis M; Tang Baiyu; Jelicks Linda A; Factor Stephen M; Shtutin Vitaliy; Tanowitz Herbert B; Lisanti Michael P
Caveolin-1 null mice develop cardiac hypertrophy with hyperactivation of p42/44 MAP kinase in cardiac fibroblasts.
American journal of physiology. Cell physiology 2003;284(2):C457-74.
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2002: Park David S; Lee Hyangkyu; Frank Philippe G; Razani Babak; Nguyen Andrew V; Parlow Albert F; Russell Robert G; Hulit James; Pestell Richard G; Lisanti Michael P
Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade.
Molecular biology of the cell 2002;13(10):3416-30.
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2002: Lee Hyangkyu; Park David S; Razani Babak; Russell Robert G; Pestell Richard G; Lisanti Michael P
Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia.
The American journal of pathology 2002;161(4):1357-69.
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2002: Frank Philippe G; Marcel Yves L; Connelly Margery A; Lublin Douglas M; Franklin Vivian; Williams David L; Lisanti Michael P
Stabilization of caveolin-1 by cellular cholesterol and scavenger receptor class B type I.
Biochemistry 2002;41(39):11931-40.
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2002: Schubert William; Frank Philippe G; Woodman Scott E; Hyogo Hideyuki; Cohen David E; Chow Chi-Wing; Lisanti Michael P
Microvascular hyperpermeability in caveolin-1 (-/-) knock-out mice. Treatment with a specific nitric-oxide synthase inhibitor, L-NAME, restores normal microvascular permeability in Cav-1 null mice.
The Journal of biological chemistry 2002;277(42):40091-8.
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2002: Woodman Scott E; Park David S; Cohen Alex W; Cheung Michelle W-C; Chandra Madhulika; Shirani Jamshid; Tang Baiyu; Jelicks Linda A; Kitsis Richard N; Christ George J; Factor Stephen M; Tanowitz Herbert B; Lisanti Michael P
Caveolin-3 knock-out mice develop a progressive cardiomyopathy and show hyperactivation of the p42/44 MAPK cascade.
The Journal of biological chemistry 2002;277(41):38988-97.
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2002: Razani Babak; Woodman Scott E; Lisanti Michael P
Caveolae: from cell biology to animal physiology.
Pharmacological reviews 2002;54(3):431-67.
-
2002: Lee Hyangkyu; Park David S; Wang Xiao Bo; Scherer Philipp E; Schwartz Phillip E; Lisanti Michael P
Src-induced phosphorylation of caveolin-2 on tyrosine 19. Phospho-caveolin-2 (Tyr(P)19) is localized near focal adhesions, remains associated with lipid rafts/caveolae, but no longer forms a high molecular mass hetero-oligomer with caveolin-1.
The Journal of biological chemistry 2002;277(37):34556-67.
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2002: Volonte Daniela; Zhang Kun; Lisanti Michael P; Galbiati Ferruccio
Expression of caveolin-1 induces premature cellular senescence in primary cultures of murine fibroblasts.
Molecular biology of the cell 2002;13(7):2502-17.
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2002: Merlini L; Carbone I; Capanni C; Sabatelli P; Tortorelli S; Sotgia F; Lisanti M P; Bruno C; Minetti C
Familial isolated hyperCKaemia associated with a new mutation in the caveolin-3 (CAV-3) gene.
Journal of neurology, neurosurgery, and psychiatry 2002;73(1):65-7.
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2002: Fu Maofu; Wang Chenguang; Wang Jian; Zafonte Brian T; Lisanti Michael P; Pestell Richard G
Acetylation in hormone signaling and the cell cycle.
Cytokine & growth factor reviews 2002;13(3):259-76.
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2002: Razani Babak; Park David S; Miyanaga Yuko; Ghatpande Ashwini; Cohen Justin; Wang Xiao Bo; Scherer Philipp E; Evans Todd; Lisanti Michael P
Molecular cloning and developmental expression of the caveolin gene family in the amphibian Xenopus laevis.
Biochemistry 2002;41(25):7914-24.
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2002: Park David S; Woodman Scott E; Schubert William; Cohen Alex W; Frank Philippe G; Chandra Madhulika; Shirani Jamshid; Razani Babak; Tang Baiyu; Jelicks Linda A; Factor Stephen M; Weiss Louis M; Tanowitz Herbert B; Lisanti Michael P
Caveolin-1/3 double-knockout mice are viable, but lack both muscle and non-muscle caveolae, and develop a severe cardiomyopathic phenotype.
The American journal of pathology 2002;160(6):2207-17.
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2002: Sotgia Federica; Razani Babak; Bonuccelli Gloria; Schubert William; Battista Michela; Lee Hyangkyu; Capozza Franco; Schubert Ann Lane; Minetti Carlo; Buckley J Thomas; Lisanti Michael P
Intracellular retention of glycosylphosphatidyl inositol-linked proteins in caveolin-deficient cells.
Molecular and cellular biology 2002;22(11):3905-26.
-
2002: Schubert Anne-Lane; Schubert William; Spray David C; Lisanti Michael P
Connexin family members target to lipid raft domains and interact with caveolin-1.
Biochemistry 2002;41(18):5754-64.
-
2002: Razani Babak; Wang Xiao Bo; Engelman Jeffery A; Battista Michela; Lagaud Guy; Zhang Xiao Lan; Kneitz Burkhard; Hou Harry; Christ George J; Edelmann Winfried; Lisanti Michael P
Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae.
Molecular and cellular biology 2002;22(7):2329-44.
-
2002: Woodman Scott E; Schlegel Amnon; Cohen Alex W; Lisanti Michael P
Mutational analysis identifies a short atypical membrane attachment sequence (KYWFYR) within caveolin-1.
Biochemistry 2002;41(11):3790-5.
-
2002: Liu Jun; Wang Xiao Bo; Park David S; Lisanti Michael P
Caveolin-1 expression enhances endothelial capillary tubule formation.
The Journal of biological chemistry 2002;277(12):10661-8.
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2002: Razani Babak; Combs Terry P; Wang Xiao Bo; Frank Philippe G; Park David S; Russell Robert G; Li Maomi; Tang Baiyu; Jelicks Linda A; Scherer Philipp E; Lisanti Michael P
Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities.
The Journal of biological chemistry 2002;277(10):8635-47.
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2002: Minetti Carlo; Bado Massimo; Broda Paolo; Sotgia Federica; Bruno Claudio; Galbiati Ferruccio; Volonte Daniela; Lucania Giuseppe; Pavan Antonio; Bonilla Eduardo; Lisanti Michael P; Cordone Giuseppe
Impairment of caveolae formation and T-system disorganization in human muscular dystrophy with caveolin-3 deficiency.
The American journal of pathology 2002;160(1):265-70.
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2001: Bouzahzah B; Albanese C; Ahmed F; Pixley F; Lisanti M P; Segall J D; Condeelis J; Joyce D; Minden A; Der C J; Chan A; Symons M; Pestell R G
Rho family GTPases regulate mammary epithelium cell growth and metastasis through distinguishable pathways.
Molecular medicine (Cambridge, Mass.) 2001;7(12):816-30.
-
2001: Razani B; Lisanti M P
Caveolin-deficient mice: insights into caveolar function human disease.
The Journal of clinical investigation 2001;108(11):1553-61.
-
2001: Sotgia F; Lee H; Bedford M T; Petrucci T; Sudol M; Lisanti M P
Tyrosine phosphorylation of beta-dystroglycan at its WW domain binding motif, PPxY, recruits SH2 domain containing proteins.
Biochemistry 2001;40(48):14585-92.
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2001: Schubert W; Frank P G; Razani B; Park D S; Chow C W; Lisanti M P
Caveolae-deficient endothelial cells show defects in the uptake and transport of albumin in vivo.
The Journal of biological chemistry 2001;276(52):48619-22.
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2001: Park D S; Lee H; Riedel C; Hulit J; Scherer P E; Pestell R G; Lisanti M P
Prolactin negatively regulates caveolin-1 gene expression in the mammary gland during lactation, via a Ras-dependent mechanism.
The Journal of biological chemistry 2001;276(51):48389-97.
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2001: Razani B; Lisanti M P
Caveolins and caveolae: molecular and functional relationships.
Experimental cell research 2001;271(1):36-44.
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2001: Galbiati F; Razani B; Lisanti M P
Caveolae and caveolin-3 in muscular dystrophy.
Trends in molecular medicine 2001;7(10):435-41.
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2001: Schlegel A; Wang C; Pestell R G; Lisanti M P
Ligand-independent activation of oestrogen receptor alpha by caveolin-1.
The Biochemical journal 2001;359(Pt 1):203-10.
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2001: Razani B; Lisanti M P
Two distinct caveolin-1 domains mediate the functional interaction of caveolin-1 with protein kinase A.
American journal of physiology. Cell physiology 2001;281(4):C1241-50.
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2001: Razani B; Engelman J A; Wang X B; Schubert W; Zhang X L; Marks C B; Macaluso F; Russell R G; Li M; Pestell R G; Di Vizio D; Hou H; Kneitz B; Lagaud G; Christ G J; Edelmann W; Lisanti M P
Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities.
The Journal of biological chemistry 2001;276(41):38121-38.
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2001: Frank P G; Pedraza A; Cohen D E; Lisanti M P
Adenovirus-mediated expression of caveolin-1 in mouse liver increases plasma high-density lipoprotein levels.
Biochemistry 2001;40(36):10892-900.
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2001: Lee H; Woodman S E; Engelman J A; Volonté D; Galbiati F; Kaufman H L; Lublin D M; Lisanti M P
Palmitoylation of caveolin-1 at a single site (Cys-156) controls its coupling to the c-Src tyrosine kinase: targeting of dually acylated molecules (GPI-linked, transmembrane, or cytoplasmic) to caveolae effectively uncouples c-Src and caveolin-1 (TYR-14).
The Journal of biological chemistry 2001;276(37):35150-8.
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2001: Galbiati F; Razani B; Lisanti M P
Emerging themes in lipid rafts and caveolae.
Cell 2001;106(4):403-11.
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2001: Galbiati F; Volonté D; Liu J; Capozza F; Frank P G; Zhu L; Pestell R G; Lisanti M P
Caveolin-1 expression negatively regulates cell cycle progression by inducing G(0)/G(1) arrest via a p53/p21(WAF1/Cip1)-dependent mechanism.
Molecular biology of the cell 2001;12(8):2229-44.
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2001: Razani B; Schlegel A; Liu J; Lisanti M P
Caveolin-1, a putative tumour suppressor gene.
Biochemical Society transactions 2001;29(Pt 4):494-9.
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2001: Galbiati F; Engelman J A; Volonte D; Zhang X L; Minetti C; Li M; Hou H; Kneitz B; Edelmann W; Lisanti M P
Caveolin-3 null mice show a loss of caveolae, changes in the microdomain distribution of the dystrophin-glycoprotein complex, and t-tubule abnormalities.
The Journal of biological chemistry 2001;276(24):21425-33.
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2001: Fine S W; Lisanti M P; Galbiati F; Li M
Elevated expression of caveolin-1 in adenocarcinoma of the colon.
American journal of clinical pathology 2001;115(5):719-24.
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2001: Frank P G; Galbiati F; Volonte D; Razani B; Cohen D E; Marcel Y L; Lisanti M P
Influence of caveolin-1 on cellular cholesterol efflux mediated by high-density lipoproteins.
American journal of physiology. Cell physiology 2001;280(5):C1204-14.
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2001: Wang C; Fu M; Angeletti R H; Siconolfi-Baez L; Reutens A T; Albanese C; Lisanti M P; Katzenellenbogen B S; Kato S; Hopp T; Fuqua S A; Lopez G N; Kushner P J; Pestell R G
Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity.
The Journal of biological chemistry 2001;276(21):18375-83.
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2001: Liu J; Lee P; Galbiati F; Kitsis R N; Lisanti M P
Caveolin-1 expression sensitizes fibroblastic and epithelial cells to apoptotic stimulation.
American journal of physiology. Cell physiology 2001;280(4):C823-35.
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2001: Schlegel A; Lisanti M P
The caveolin triad: caveolae biogenesis, cholesterol trafficking, and signal transduction.
Cytokine & growth factor reviews 2001;12(1):41-51.
-
2001: Schlegel A; Lisanti M P
Caveolae and their coat proteins, the caveolins: from electron microscopic novelty to biological launching pad.
Journal of cellular physiology 2001;186(3):329-37.
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2001: Razani B; Zhang X L; Bitzer M; von Gersdorff G; Böttinger E P; Lisanti M P
Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signaling through an interaction with the TGF-beta type I receptor.
The Journal of biological chemistry 2001;276(9):6727-38.
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2001: Volonté D; Galbiati F; Pestell R G; Lisanti M P
Cellular stress induces the tyrosine phosphorylation of caveolin-1 (Tyr(14)) via activation of p38 mitogen-activated protein kinase and c-Src kinase. Evidence for caveolae, the actin cytoskeleton, and focal adhesions as mechanical sensors of osmotic stress.
The Journal of biological chemistry 2001;276(11):8094-103.
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2001: Schlegel A; Arvan P; Lisanti M P
Caveolin-1 binding to endoplasmic reticulum membranes and entry into the regulated secretory pathway are regulated by serine phosphorylation. Protein sorting at the level of the endoplasmic reticulum.
The Journal of biological chemistry 2001;276(6):4398-408.
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2000: Zafonte B T; Hulit J; Amanatullah D F; Albanese C; Wang C; Rosen E; Reutens A; Sparano J A; Lisanti M P; Pestell R G
Cell-cycle dysregulation in breast cancer: breast cancer therapies targeting the cell cycle.
Frontiers in bioscience : a journal and virtual library 2000;5():D938-61.
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2000: Sotgia F; Lee J K; Das K; Bedford M; Petrucci T C; Macioce P; Sargiacomo M; Bricarelli F D; Minetti C; Sudol M; Lisanti M P
Caveolin-3 directly interacts with the C-terminal tail of beta -dystroglycan. Identification of a central WW-like domain within caveolin family members.
The Journal of biological chemistry 2000;275(48):38048-58.
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2000: Galbiati F; Volonte D; Minetti C; Bregman D B; Lisanti M P
Limb-girdle muscular dystrophy (LGMD-1C) mutants of caveolin-3 undergo ubiquitination and proteasomal degradation. Treatment with proteasomal inhibitors blocks the dominant negative effect of LGMD-1C mutanta and rescues wild-type caveolin-3.
The Journal of biological chemistry 2000;275(48):37702-11.
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2000: Huang H; Petkova S B; Pestell R G; Bouzahzah B; Chan J; Magazine H; Weiss L M; Christ G J; Lisanti M P; Douglas S A; Shtutin V; Halonen S K; Wittner M; Tanowitz H B
Trypanosoma cruzi infection (Chagas' disease) of mice causes activation of the mitogen-activated protein kinase cascade and expression of endothelin-1 in the myocardium.
Journal of cardiovascular pharmacology 2000;36(5 Suppl 1):S148-50.
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2000: Razani B; Altschuler Y; Zhu L; Pestell R G; Mostov K E; Lisanti M P
Caveolin-1 expression is down-regulated in cells transformed by the human papilloma virus in a p53-dependent manner. Replacement of caveolin-1 expression suppresses HPV-mediated cell transformation.
Biochemistry 2000;39(45):13916-24.
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2000: Lee H; Volonte D; Galbiati F; Iyengar P; Lublin D M; Bregman D B; Wilson M T; Campos-Gonzalez R; Bouzahzah B; Pestell R G; Scherer P E; Lisanti M P
Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette.
Molecular endocrinology (Baltimore, Md.) 2000;14(11):1750-75.
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2000: Engelman J A; Berg A H; Lewis R Y; Lisanti M P; Scherer P E
Tumor necrosis factor alpha-mediated insulin resistance, but not dedifferentiation, is abrogated by MEK1/2 inhibitors in 3T3-L1 adipocytes.
Molecular endocrinology (Baltimore, Md.) 2000;14(10):1557-69.
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2000: D'Amico M; Hulit J; Amanatullah D F; Zafonte B T; Albanese C; Bouzahzah B; Fu M; Augenlicht L H; Donehower L A; Takemaru K; Moon R T; Davis R; Lisanti M P; Shtutman M; Zhurinsky J; Ben-Ze'ev A; Troussard A A; Dedhar S; Pestell R G
The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways.
The Journal of biological chemistry 2000;275(42):32649-57.
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2000: Galbiati F; Volonte D; Brown A M; Weinstein D E; Ben-Ze'ev A; Pestell R G; Lisanti M P
Caveolin-1 expression inhibits Wnt/beta-catenin/Lef-1 signaling by recruiting beta-catenin to caveolae membrane domains.
The Journal of biological chemistry 2000;275(30):23368-77.
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2000: Schlegel A; Lisanti M P
A molecular dissection of caveolin-1 membrane attachment and oligomerization. Two separate regions of the caveolin-1 C-terminal domain mediate membrane binding and oligomer/oligomer interactions in vivo.
The Journal of biological chemistry 2000;275(28):21605-17.
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2000: Zhang W; Razani B; Altschuler Y; Bouzahzah B; Mostov K E; Pestell R G; Lisanti M P
Caveolin-1 inhibits epidermal growth factor-stimulated lamellipod extension and cell migration in metastatic mammary adenocarcinoma cells (MTLn3). Transformation suppressor effects of adenovirus-mediated gene delivery of caveolin-1.
The Journal of biological chemistry 2000;275(27):20717-25.
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2000: Hulit J; Bash T; Fu M; Galbiati F; Albanese C; Sage D R; Schlegel A; Zhurinsky J; Shtutman M; Ben-Ze'ev A; Lisanti M P; Pestell R G
The cyclin D1 gene is transcriptionally repressed by caveolin-1.
The Journal of biological chemistry 2000;275(28):21203-9.
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2000: Razani B; Schlegel A; Lisanti M P
Caveolin proteins in signaling, oncogenic transformation and muscular dystrophy.
Journal of cell science 2000;113 ( Pt 12)():2103-9.
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2000: Carbone I; Bruno C; Sotgia F; Bado M; Broda P; Masetti E; Panella A; Zara F; Bricarelli F D; Cordone G; Lisanti M P; Minetti C
Mutation in the CAV3 gene causes partial caveolin-3 deficiency and hyperCKemia.
Neurology 2000;54(6):1373-6.
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1999: Engelman J A; Berg A H; Lewis R Y; Lin A; Lisanti M P; Scherer P E
Constitutively active mitogen-activated protein kinase kinase 6 (MKK6) or salicylate induces spontaneous 3T3-L1 adipogenesis.
The Journal of biological chemistry 1999;274(50):35630-8.
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1999: Engelman J A; Zhang X L; Razani B; Pestell R G; Lisanti M P
p42/44 MAP kinase-dependent and -independent signaling pathways regulate caveolin-1 gene expression. Activation of Ras-MAP kinase and protein kinase a signaling cascades transcriptionally down-regulates caveolin-1 promoter activity.
The Journal of biological chemistry 1999;274(45):32333-41.
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1999: Galbiati F; Volonte D; Engelman J A; Scherer P E; Lisanti M P
Targeted down-regulation of caveolin-3 is sufficient to inhibit myotube formation in differentiating C2C12 myoblasts. Transient activation of p38 mitogen-activated protein kinase is required for induction of caveolin-3 expression and subsequent myotube formation.
The Journal of biological chemistry 1999;274(42):30315-21.
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1999: Bàthori G; Parolini I; Tombola F; Szabò I; Messina A; Oliva M; De Pinto V; Lisanti M; Sargiacomo M; Zoratti M
Porin is present in the plasma membrane where it is concentrated in caveolae and caveolae-related domains.
The Journal of biological chemistry 1999;274(42):29607-12.
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1999: Razani B; Rubin C S; Lisanti M P
Regulation of cAMP-mediated signal transduction via interaction of caveolins with the catalytic subunit of protein kinase A.
The Journal of biological chemistry 1999;274(37):26353-60.
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1999: Parolini I; Sargiacomo M; Galbiati F; Rizzo G; Grignani F; Engelman J A; Okamoto T; Ikezu T; Scherer P E; Mora R; Rodriguez-Boulan E; Peschle C; Lisanti M P
Expression of caveolin-1 is required for the transport of caveolin-2 to the plasma membrane. Retention of caveolin-2 at the level of the golgi complex.
The Journal of biological chemistry 1999;274(36):25718-25.
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1999: Galbiati F; Volonte D; Minetti C; Chu J B; Lisanti M P
Phenotypic behavior of caveolin-3 mutations that cause autosomal dominant limb girdle muscular dystrophy (LGMD-1C). Retention of LGMD-1C caveolin-3 mutants within the golgi complex.
The Journal of biological chemistry 1999;274(36):25632-41.
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1999: Repetto S; Bado M; Broda P; Lucania G; Masetti E; Sotgia F; Carbone I; Pavan A; Bonilla E; Cordone G; Lisanti M P; Minetti C
Increased number of caveolae and caveolin-3 overexpression in Duchenne muscular dystrophy.
Biochemical and biophysical research communications 1999;261(3):547-50.
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1999: Schlegel A; Schwab R B; Scherer P E; Lisanti M P
A role for the caveolin scaffolding domain in mediating the membrane attachment of caveolin-1. The caveolin scaffolding domain is both necessary and sufficient for membrane binding in vitro.
The Journal of biological chemistry 1999;274(32):22660-7.
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1999: Nishiyama K; Trapp B D; Ikezu T; Ransohoff R M; Tomita T; Iwatsubo T; Kanazawa I; Hsiao K K; Lisanti M P; Okamoto T
Caveolin-3 upregulation activates beta-secretase-mediated cleavage of the amyloid precursor protein in Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(15):6538-48.
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1999: Sotgia F; Minetti C; Lisanti M P
Localization of the human caveolin-3 gene to the D3S18/D3S4163/D3S4539 locus (3p25), in close proximity to the human oxytocin receptor gene. Identification of the caveolin-3 gene as a candidate for deletion in 3p-syndrome.
FEBS letters 1999;452(3):177-80.
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1999: Das K; Lewis R Y; Scherer P E; Lisanti M P
The membrane-spanning domains of caveolins-1 and -2 mediate the formation of caveolin hetero-oligomers. Implications for the assembly of caveolae membranes in vivo.
The Journal of biological chemistry 1999;274(26):18721-8.
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1999: Liu J; Razani B; Tang S; Terman B I; Ware J A; Lisanti M P
Angiogenesis activators and inhibitors differentially regulate caveolin-1 expression and caveolae formation in vascular endothelial cells. Angiogenesis inhibitors block vascular endothelial growth factor-induced down-regulation of caveolin-1.
The Journal of biological chemistry 1999;274(22):15781-5.
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1999: Parolini I; Topa S; Sorice M; Pace A; Ceddia P; Montesoro E; Pavan A; Lisanti M P; Peschle C; Sargiacomo M
Phorbol ester-induced disruption of the CD4-Lck complex occurs within a detergent-resistant microdomain of the plasma membrane. Involvement of the translocation of activated protein kinase C isoforms.
The Journal of biological chemistry 1999;274(20):14176-87.
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1999: Engelman J A; Zhang X L; Lisanti M P
Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1). Methylation of a CpG island in the 5' promoter region of the caveolin-1 gene in human breast cancer cell lines.
FEBS letters 1999;448(2-3):221-30.
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1999: Volonte D; Galbiati F; Li S; Nishiyama K; Okamoto T; Lisanti M P
Flotillins/cavatellins are differentially expressed in cells and tissues and form a hetero-oligomeric complex with caveolins in vivo. Characterization and epitope-mapping of a novel flotillin-1 monoclonal antibody probe.
The Journal of biological chemistry 1999;274(18):12702-9.
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1999: Carman C V; Lisanti M P; Benovic J L
Regulation of G protein-coupled receptor kinases by caveolin.
The Journal of biological chemistry 1999;274(13):8858-64.
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1999: Volonte D; Galbiati F; Lisanti M P
Visualization of caveolin-1, a caveolar marker protein, in living cells using green fluorescent protein (GFP) chimeras. The subcellular distribution of caveolin-1 is modulated by cell-cell contact.
FEBS letters 1999;445(2-3):431-9.
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1999: Galbiati F; Volonte D; Meani D; Milligan G; Lublin D M; Lisanti M P; Parenti M
The dually acylated NH2-terminal domain of gi1alpha is sufficient to target a green fluorescent protein reporter to caveolin-enriched plasma membrane domains. Palmitoylation of caveolin-1 is required for the recognition of dually acylated g-protein alpha subunits in vivo.
The Journal of biological chemistry 1999;274(9):5843-50.
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1999: Lisanti M P; Sargiacomo M; Scherer P E
Purification of caveolae-derived membrane microdomains containing lipid-anchored signaling molecules, such as GPI-anchored proteins, H-Ras, Src-family tyrosine kinases, eNOS, and G-protein alpha-, beta-, and gamma-subunits.
Methods in molecular biology (Clifton, N.J.) 1999;116():51-60.
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1998: Engelman J A; Zhang X; Galbiati F; Volonte D; Sotgia F; Pestell R G; Minetti C; Scherer P E; Okamoto T; Lisanti M P
Molecular genetics of the caveolin gene family: implications for human cancers, diabetes, Alzheimer disease, and muscular dystrophy.
American journal of human genetics 1998;63(6):1578-87.
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1998: Yang C P; Galbiati F; Volonte D; Horwitz S B; Lisanti M P
Upregulation of caveolin-1 and caveolae organelles in Taxol-resistant A549 cells.
FEBS letters 1998;439(3):368-72.
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1998: Engelman J A; Lisanti M P; Scherer P E
Specific inhibitors of p38 mitogen-activated protein kinase block 3T3-L1 adipogenesis.
The Journal of biological chemistry 1998;273(48):32111-20.
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1998: Galbiati F; Volonte D; Engelman J A; Watanabe G; Burk R; Pestell R G; Lisanti M P
Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade.
The EMBO journal 1998;17(22):6633-48.
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1998: Engelman J A; Zhang X L; Lisanti M P
Genes encoding human caveolin-1 and -2 are co-localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers.
FEBS letters 1998;436(3):403-10.
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1998: Ikezu T; Ueda H; Trapp B D; Nishiyama K; Sha J F; Volonte D; Galbiati F; Byrd A L; Bassell G; Serizawa H; Lane W S; Lisanti M P; Okamoto T
Affinity-purification and characterization of caveolins from the brain: differential expression of caveolin-1, -2, and -3 in brain endothelial and astroglial cell types.
Brain research 1998;804(2):177-92.
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1998: Li S; Galbiati F; Volonte D; Sargiacomo M; Engelman J A; Das K; Scherer P E; Lisanti M P
Mutational analysis of caveolin-induced vesicle formation. Expression of caveolin-1 recruits caveolin-2 to caveolae membranes.
FEBS letters 1998;434(1-2):127-34.
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1998: Galbiati F; Volonte D; Gil O; Zanazzi G; Salzer J L; Sargiacomo M; Scherer P E; Engelman J A; Schlegel A; Parenti M; Okamoto T; Lisanti M P
Expression of caveolin-1 and -2 in differentiating PC12 cells and dorsal root ganglion neurons: caveolin-2 is up-regulated in response to cell injury.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(17):10257-62.
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1998: Engelman J A; Lee R J; Karnezis A; Bearss D J; Webster M; Siegel P; Muller W J; Windle J J; Pestell R G; Lisanti M P
Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer.
The Journal of biological chemistry 1998;273(32):20448-55.
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1998: Schlegel A; Volonte D; Engelman J A; Galbiati F; Mehta P; Zhang X L; Scherer P E; Lisanti M P
Crowded little caves: structure and function of caveolae.
Cellular signalling 1998;10(7):457-63.
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1998: Engelman J A; Zhang X L; Galbiati F; Lisanti M P
Chromosomal localization, genomic organization, and developmental expression of the murine caveolin gene family (Cav-1, -2, and -3). Cav-1 and Cav-2 genes map to a known tumor suppressor locus (6-A2/7q31).
FEBS letters 1998;429(3):330-6.
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1998: Engelman J A; Chu C; Lin A; Jo H; Ikezu T; Okamoto T; Kohtz D S; Lisanti M P
Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domain.
FEBS letters 1998;428(3):205-11.
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1998: Ikezu T; Trapp B D; Song K S; Schlegel A; Lisanti M P; Okamoto T
Caveolae, plasma membrane microdomains for alpha-secretase-mediated processing of the amyloid precursor protein.
The Journal of biological chemistry 1998;273(17):10485-95.
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1998: Minetti C; Sotgia F; Bruno C; Scartezzini P; Broda P; Bado M; Masetti E; Mazzocco M; Egeo A; Donati M A; Volonte D; Galbiati F; Cordone G; Bricarelli F D; Lisanti M P; Zara F
Mutations in the caveolin-3 gene cause autosomal dominant limb-girdle muscular dystrophy.
Nature genetics 1998;18(4):365-8.
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1998: Okamoto T; Schlegel A; Scherer P E; Lisanti M P
Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane.
The Journal of biological chemistry 1998;273(10):5419-22.
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1998: Breton S; Lisanti M P; Tyszkowski R; McLaughlin M; Brown D
Basolateral distribution of caveolin-1 in the kidney. Absence from H+-atpase-coated endocytic vesicles in intercalated cells.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1998;46(2):205-14.
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1997: Scherer P E; Lewis R Y; Volonte D; Engelman J A; Galbiati F; Couet J; Kohtz D S; van Donselaar E; Peters P; Lisanti M P
Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo.
The Journal of biological chemistry 1997;272(46):29337-46.
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1997: Scherer P E; Lisanti M P
Association of phosphofructokinase-M with caveolin-3 in differentiated skeletal myotubes. Dynamic regulation by extracellular glucose and intracellular metabolites.
The Journal of biological chemistry 1997;272(33):20698-705.
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1997: Engelman J A; Wykoff C C; Yasuhara S; Song K S; Okamoto T; Lisanti M P
Recombinant expression of caveolin-1 in oncogenically transformed cells abrogates anchorage-independent growth.
The Journal of biological chemistry 1997;272(26):16374-81.
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1997: Song K S; Sargiacomo M; Galbiati F; Parenti M; Lisanti M P
Targeting of a G alpha subunit (Gi1 alpha) and c-Src tyrosine kinase to caveolae membranes: clarifying the role of N-myristoylation.
Cellular and molecular biology (Noisy-le-Grand, France) 1997;43(3):293-303.
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1997: Bickel P E; Scherer P E; Schnitzer J E; Oh P; Lisanti M P; Lodish H F
Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins.
The Journal of biological chemistry 1997;272(21):13793-802.
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1997: Couet J; Li S; Okamoto T; Ikezu T; Lisanti M P
Identification of peptide and protein ligands for the caveolin-scaffolding domain. Implications for the interaction of caveolin with caveolae-associated proteins.
The Journal of biological chemistry 1997;272(10):6525-33.
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1997: Song K S; Tang Z; Li S; Lisanti M P
Mutational analysis of the properties of caveolin-1. A novel role for the C-terminal domain in mediating homo-typic caveolin-caveolin interactions.
The Journal of biological chemistry 1997;272(7):4398-403.
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1996: Kübler E; Dohlman H G; Lisanti M P
Identification of Triton X-100 insoluble membrane domains in the yeast Saccharomyces cerevisiae. Lipid requirements for targeting of heterotrimeric G-protein subunits.
The Journal of biological chemistry 1996;271(51):32975-80.
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1996: Li S; Couet J; Lisanti M P
Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases.
The Journal of biological chemistry 1996;271(46):29182-90.
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1996: Li S; Song K S; Koh S S; Kikuchi A; Lisanti M P
Baculovirus-based expression of mammalian caveolin in Sf21 insect cells. A model system for the biochemical and morphological study of caveolae biogenesis.
The Journal of biological chemistry 1996;271(45):28647-54.
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1996: Song K S; Scherer P E; Tang Z; Okamoto T; Li S; Chafel M; Chu C; Kohtz D S; Lisanti M P
Expression of caveolin-3 in skeletal, cardiac, and smooth muscle cells. Caveolin-3 is a component of the sarcolemma and co-fractionates with dystrophin and dystrophin-associated glycoproteins.
The Journal of biological chemistry 1996;271(25):15160-5.
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1996: Parolini I; Sargiacomo M; Lisanti M P; Peschle C
Signal transduction and glycophosphatidylinositol-linked proteins (lyn, lck, CD4, CD45, G proteins, and CD55) selectively localize in Triton-insoluble plasma membrane domains of human leukemic cell lines and normal granulocytes.
Blood 1996;87(9):3783-94.
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1996: Song K S; Li Shengwen; Okamoto T; Quilliam L A; Sargiacomo M; Lisanti M P
Co-purification and direct interaction of Ras with caveolin, an integral membrane protein of caveolae microdomains. Detergent-free purification of caveolae microdomains.
The Journal of biological chemistry 1996;271(16):9690-7.
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1996: Li S; Seitz R; Lisanti M P
Phosphorylation of caveolin by src tyrosine kinases. The alpha-isoform of caveolin is selectively phosphorylated by v-Src in vivo.
The Journal of biological chemistry 1996;271(7):3863-8.
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1996: Tang Z; Scherer P E; Okamoto T; Song K; Chu C; Kohtz D S; Nishimoto I; Lodish H F; Lisanti M P
Molecular cloning of caveolin-3, a novel member of the caveolin gene family expressed predominantly in muscle.
The Journal of biological chemistry 1996;271(4):2255-61.
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1996: Scherer P E; Okamoto T; Chun M; Nishimoto I; Lodish H F; Lisanti M P
Identification, sequence, and expression of caveolin-2 defines a caveolin gene family.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(1):131-5.
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1996: Li S; Song K S; Lisanti M P
Expression and characterization of recombinant caveolin. Purification by polyhistidine tagging and cholesterol-dependent incorporation into defined lipid membranes.
The Journal of biological chemistry 1996;271(1):568-73.
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1995: Sargiacomo M; Scherer P E; Tang Z; Kübler E; Song K S; Sanders M C; Lisanti M P
Oligomeric structure of caveolin: implications for caveolae membrane organization.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(20):9407-11.
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1995: Scherer P E; Tang Z; Chun M; Sargiacomo M; Lodish H F; Lisanti M P
Caveolin isoforms differ in their N-terminal protein sequence and subcellular distribution. Identification and epitope mapping of an isoform-specific monoclonal antibody probe.
The Journal of biological chemistry 1995;270(27):16395-401.
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1995: Li S; Okamoto T; Chun M; Sargiacomo M; Casanova J E; Hansen S H; Nishimoto I; Lisanti M P
Evidence for a regulated interaction between heterotrimeric G proteins and caveolin.
The Journal of biological chemistry 1995;270(26):15693-701.
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1995: Koleske A J; Baltimore D; Lisanti M P
Reduction of caveolin and caveolae in oncogenically transformed cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(5):1381-5.
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1995: Lisanti M P; Tang Z; Scherer P E; Kübler E; Koleske A J; Sargiacomo M
Caveolae, transmembrane signalling and cellular transformation.
Molecular membrane biology 1995;12(1):121-4.
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1995: Lisanti M P; Tang Z; Scherer P E; Sargiacomo M
Caveolae purification and glycosylphosphatidylinositol-linked protein sorting in polarized epithelia.
Methods in enzymology 1995;250():655-68.
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1994: Scherer P E; Lisanti M P; Baldini G; Sargiacomo M; Mastick C C; Lodish H F
Induction of caveolin during adipogenesis and association of GLUT4 with caveolin-rich vesicles.
The Journal of cell biology 1994;127(5):1233-43.
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1994: Chun M; Liyanage U K; Lisanti M P; Lodish H F
Signal transduction of a G protein-coupled receptor in caveolae: colocalization of endothelin and its receptor with caveolin.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(24):11728-32.
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1994: Sargiacomo M; Scherer P E; Tang Z L; Casanova J E; Lisanti M P
In vitro phosphorylation of caveolin-rich membrane domains: identification of an associated serine kinase activity as a casein kinase II-like enzyme.
Oncogene 1994;9(9):2589-95.
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1994: Tang Z L; Scherer P E; Lisanti M P
The primary sequence of murine caveolin reveals a conserved consensus site for phosphorylation by protein kinase C.
Gene 1994;147(2):299-300.
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1994: Lisanti M P; Scherer P E; Vidugiriene J; Tang Z; Hermanowski-Vosatka A; Tu Y H; Cook R F; Sargiacomo M
Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease.
The Journal of cell biology 1994;126(1):111-26.
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1993: Lisanti M P; Tang Z L; Sargiacomo M
Caveolin forms a hetero-oligomeric protein complex that interacts with an apical GPI-linked protein: implications for the biogenesis of caveolae.
The Journal of cell biology 1993;123(3):595-604.
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1993: Sargiacomo M; Sudol M; Tang Z; Lisanti M P
Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells.
The Journal of cell biology 1993;122(4):789-807.
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