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Peter Barnes
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181
Chung, Fan
100
Kharitonov, Sergei
98
Adcock, Ian
67
Belvisi, Maria
53
Giembycz, Mark
47
Rogers, Duncan
46
Mak, Judith
37
Ito, Kazuhiro
34
Donnelly, Louise
33
Newton, Robert
30
Lim, Sam
29
O'connor, Brian
29
Haddad, EB
28
Evans, Timothy
25
Hansel, Trevor
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All Publications
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2009: Barnes Peter J
The cytokine network in chronic obstructive pulmonary disease.
American journal of respiratory cell and molecular biology 2009;41(6):631-8.
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2009: Barnes Peter J
Histone deacetylase-2 and airway disease.
Therapeutic advances in respiratory disease 2009;3(5):235-43.
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2009: Nakamaru Yuji; Vuppusetty Chaitanya; Wada Hiroo; Milne Jill C; Ito Misako; Rossios Christos; Elliot Mark; Hogg James; Kharitonov Sergei; Goto Hajime; Bemis Jean E; Elliott Peter; Barnes Peter J; Ito Kazuhiro
A protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(9):2810-9.
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2009: Hansel Trevor T; Barnes Peter J
New drugs for exacerbations of chronic obstructive pulmonary disease.
Lancet 2009;374(9691):744-55.
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2009: Barnes P J
Intrinsic asthma: not so different from allergic asthma but driven by superantigens?
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(8):1145-51.
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2009: Osoata Grace O; Yamamura Satoshi; Ito Misako; Vuppusetty Chaitanya; Adcock Ian M; Barnes Peter J; Ito Kazuhiro
Nitration of distinct tyrosine residues causes inactivation of histone deacetylase 2.
Biochemical and biophysical research communications 2009;384(3):366-71.
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2009: Osoata Grace O; Hanazawa Toyoyuki; Brindicci Caterina; Ito Misako; Barnes Peter J; Kharitonov Sergei; Ito Kazuhiro
Peroxynitrite elevation in exhaled breath condensate of COPD and its inhibition by fudosteine.
Chest 2009;135(6):1513-20.
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2009: Barnes Peter J; Adcock Ian M
Glucocorticoid resistance in inflammatory diseases.
Lancet 2009;373(9678):1905-17.
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2009: Maneechotesuwan Kittipong; Yao Xin; Ito Kazuhiro; Jazrawi Elen; Usmani Omar S; Adcock Ian M; Barnes Peter J
Suppression of GATA-3 nuclear import and phosphorylation: a novel mechanism of corticosteroid action in allergic disease.
PLoS medicine 2009;6(5):e1000076.
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2009: Barnes P J; Celli B R
Systemic manifestations and comorbidities of COPD.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2009;33(5):1165-85.
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2009: Paredi P; Barnes P J
The airway vasculature: recent advances and clinical implications.
Thorax 2009;64(5):444-50.
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2009: Finney-Hayward T K; Bahra P; Li S; Poll C T; Nicholson A G; Russell R E K; Ford P A; Westwick J; Fenwick P S; Barnes P J; Donnelly L E
Leukotriene B4 release by human lung macrophages via receptor- not voltage-operated Ca2+ channels.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2009;33(5):1105-12.
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2009: Marwick John A; Caramori Gaetano; Stevenson Christopher S; Casolari Paolo; Jazrawi Elen; Barnes Peter J; Ito Kazuhiro; Adcock Ian M; Kirkham Paul A; Papi Alberto
Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice.
American journal of respiratory and critical care medicine 2009;179(7):542-8.
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2009: Brindicci Caterina; Ito Kazuhiro; Torre Olga; Barnes Peter J; Kharitonov Sergei A
Effects of aminoguanidine, an inhibitor of inducible nitric oxide synthase, on nitric oxide production and its metabolites in healthy control subjects, healthy smokers, and COPD patients.
Chest 2009;135(2):353-67.
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2009: Ito Kazuhiro; Barnes Peter J
COPD as a disease of accelerated lung aging.
Chest 2009;135(1):173-80.
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2009: Maneechotesuwan Kittipong; Wamanuttajinda Valla; Kasetsinsombat Kanda; Huabprasert Sukit; Yaikwawong Metha; Barnes Peter J; Wongkajornsilp Adisak
Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma.
The Journal of allergy and clinical immunology 2009;123(1):239-48.
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2009: Ford Paul A; Russell Richard Ek; Barnes Peter J
ICS and COPD: Time to clear the air.
International journal of chronic obstructive pulmonary disease 2009;4(2):289-90.
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2009: Barnes Peter J
Role of HDAC2 in the pathophysiology of COPD.
Annual review of physiology 2009;71():451-64.
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2008: Barnes Peter J
Emerging pharmacotherapies for COPD.
Chest 2008;134(6):1278-86.
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2008: Barnes Peter J
Future treatments for chronic obstructive pulmonary disease and its comorbidities.
Proceedings of the American Thoracic Society 2008;5(8):857-64.
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2008: O'Byrne Paul M; Naya Ian P; Kallen Anders; Postma Dirkje S; Barnes Peter J
Increasing doses of inhaled corticosteroids compared to adding long-acting inhaled beta2-agonists in achieving asthma control.
Chest 2008;134(6):1192-9.
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2008: Barnes Peter J
The cytokine network in asthma and chronic obstructive pulmonary disease.
The Journal of clinical investigation 2008;118(11):3546-56.
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2008: Torre O; Olivieri D; Barnes P J; Kharitonov S A
Feasibility and interpretation of FE(NO) measurements in asthma patients in general practice.
Respiratory medicine 2008;102(10):1417-24.
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2008: Erin Edward M; Zacharasiewicz Angela S; Nicholson Grant C; Tan Andrew J; Neighbour Helen; Engelstätter Renate; Hellwig Michael; Kon Onn Min; Barnes Peter J; Hansel Trevor T
Rapid effect of inhaled ciclesonide in asthma: a randomized, placebo-controlled study.
Chest 2008;134(4):740-5.
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2008: Bhavsar P; Hew M; Khorasani N; Torrego A; Barnes P J; Adcock I; Chung K F
Relative corticosteroid insensitivity of alveolar macrophages in severe asthma compared with non-severe asthma.
Thorax 2008;63(9):784-90.
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2008: Barnes Peter J
Role of GATA-3 in allergic diseases.
Current molecular medicine 2008;8(5):330-4.
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2008: Adcock Ian M; Barnes Peter J
Molecular mechanisms of corticosteroid resistance.
Chest 2008;134(2):394-401.
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2008: Sturton Graham; Persson Carl; Barnes Peter J
Small airways: an important but neglected target in the treatment of obstructive airway diseases.
Trends in pharmacological sciences 2008;29(7):340-5.
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2008: Barnes Peter J
Frontrunners in novel pharmacotherapy of COPD.
Current opinion in pharmacology 2008;8(3):300-7.
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2008: Ahmad Tehireem; Barnes Peter J; Adcock Ian M
Overcoming steroid insensitivity in smoking asthmatics.
Current opinion in investigational drugs (London, England : 2000) 2008;9(5):470-7.
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2008: Barnes Peter J
A blood test for lung fibrosis.
PLoS medicine 2008;5(4):e98.
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2008: Barnes Peter J
Immunology of asthma and chronic obstructive pulmonary disease.
Nature reviews. Immunology 2008;8(3):183-92.
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2008: Maneechotesuwan Kittipong; Supawita Sirinya; Kasetsinsombat Kanda; Wongkajornsilp Adisak; Barnes Peter J
Sputum indoleamine-2, 3-dioxygenase activity is increased in asthmatic airways by using inhaled corticosteroids.
The Journal of allergy and clinical immunology 2008;121(1):43-50.
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2008: Erin Edward M; Jenkins Gavin R; Kon Onn Min; Zacharasiewicz Angela S; Nicholson Grant C; Neighbour Helen; Tennant Rachel C; Tan Andrew J; Leaker Brian R; Bush Andrew; Jose Peter J; Barnes Peter J; Hansel Trevor T
Optimized dialysis and protease inhibition of sputum dithiothreitol supernatants.
American journal of respiratory and critical care medicine 2008;177(2):132-41.
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2008: Costa Claudia; Rufino Rogerio; Traves Suzanne L; Lapa E Silva Jose Roberto; Barnes Peter J; Donnelly Louise E
CXCR3 and CCR5 chemokines in induced sputum from patients with COPD.
Chest 2008;133(1):26-33.
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2008: Tudhope Susan J; Finney-Hayward Tricia K; Nicholson Andrew G; Mayer Ruth J; Barnette Mary S; Barnes Peter J; Donnelly Louise E
Different mitogen-activated protein kinase-dependent cytokine responses in cells of the monocyte lineage.
The Journal of pharmacology and experimental therapeutics 2008;324(1):306-12.
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2007: Tudhope Susan J; Catley Matthew C; Fenwick Peter S; Russell Richard E K; Rumsey William L; Newton Robert; Barnes Peter J; Donnelly Louise E
The role of IkappaB kinase 2, but not activation of NF-kappaB, in the release of CXCR3 ligands from IFN-gamma-stimulated human bronchial epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(9):6237-45.
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2007: Barnes Peter J
Using a combination inhaler (budesonide plus formoterol) as rescue therapy improves asthma control.
BMJ (Clinical research ed.) 2007;335(7618):513.
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2007: Brindicci Caterina; Ito Kazuhiro; Barnes Peter J; Kharitonov Sergei A
Effect of an inducible nitric oxide synthase inhibitor on differential flow-exhaled nitric oxide in asthmatic patients and healthy volunteers.
Chest 2007;132(2):581-8.
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2007: Maneechotesuwan Kittipong; Essilfie-Quaye Sarah; Kharitonov Sergei A; Adcock Ian M; Barnes Peter J
Loss of control of asthma following inhaled corticosteroid withdrawal is associated with increased sputum interleukin-8 and neutrophils.
Chest 2007;132(1):98-105.
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2007: Barnes Peter J
Chronic obstructive pulmonary disease: a growing but neglected global epidemic.
PLoS medicine 2007;4(5):e112.
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2007: Brindicci Caterina; Ito Kazuhiro; Barnes Peter J; Kharitonov Sergei A
Differential flow analysis of exhaled nitric oxide in patients with asthma of differing severity.
Chest 2007;131(5):1353-62.
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2007: Barnes Peter J
New molecular targets for the treatment of neutrophilic diseases.
The Journal of allergy and clinical immunology 2007;119(5):1055-62; quiz 1063-4.
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2007: Newton Robert; Holden Neil S; Catley Matthew C; Oyelusi Wale; Leigh Richard; Proud David; Barnes Peter J
Repression of inflammatory gene expression in human pulmonary epithelial cells by small-molecule IkappaB kinase inhibitors.
The Journal of pharmacology and experimental therapeutics 2007;321(2):734-42.
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2007: Paredi Paolo; Ward Simon; Cramer Derek; Barnes Peter J; Kharitonov Sergei A
Normal bronchial blood flow in COPD is unaffected by inhaled corticosteroids and correlates with exhaled nitric oxide.
Chest 2007;131(4):1075-81.
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2007: Barnes P J
Scientific rationale for using a single inhaler for asthma control.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2007;29(3):587-95.
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2007: Maneechotesuwan Kittipong; Xin Yao; Ito Kazuhiro; Jazrawi Elen; Lee Kang-Yun; Usmani Omar S; Barnes Peter J; Adcock Ian M
Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(4):2491-8.
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2007: Williams Andrew E; Moschos Sterghios A; Perry Mark M; Barnes Peter J; Lindsay Mark A
Maternally imprinted microRNAs are differentially expressed during mouse and human lung development.
Developmental dynamics : an official publication of the American Association of Anatomists 2007;236(2):572-80.
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2007: Ford Paul A; Barnes Peter J; Usmani Omar S
Chronic cough and Holmes-Adie syndrome.
Lancet 2007;369(9558):342.
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2007: Barnes Peter J
The problem of cough and development of novel antitussives.
Pulmonary pharmacology & therapeutics 2007;20(4):416-22.
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2007: Nicholson Grant C; Tennant Rachel C; Carpenter Donald C; Sarau Henry M; Kon Onn Min; Barnes Peter J; Salmon Michael; Vessey Rupert S; Tal-Singer Ruth; Hansel Trevor T
A novel flow cytometric assay of human whole blood neutrophil and monocyte CD11b levels: upregulation by chemokines is related to receptor expression, comparison with neutrophil shape change, and effects of a chemokine receptor (CXCR2) antagonist.
Pulmonary pharmacology & therapeutics 2007;20(1):52-9.
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2006: Kharitonov Sergei A; Barnes Peter J
Exhaled biomarkers.
Chest 2006;130(5):1541-6.
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2006: Vasavda Nisha; Eichholtz Thomas; Takahashi Atsushi; Affleck Karen; Matthews John G; Barnes Peter J; Adcock Ian M
Expression of nonmuscle cofilin-1 and steroid responsiveness in severe asthma.
The Journal of allergy and clinical immunology 2006;118(5):1090-6.
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2006: Barnes Peter J
New therapies for asthma.
Trends in molecular medicine 2006;12(11):515-20.
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2006: Smith S J; Fenwick P S; Nicholson A G; Kirschenbaum F; Finney-Hayward T K; Higgins L S; Giembycz M A; Barnes P J; Donnelly L E
Inhibitory effect of p38 mitogen-activated protein kinase inhibitors on cytokine release from human macrophages.
British journal of pharmacology 2006;149(4):393-404.
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2006: Donnelly Louise E; Barnes Peter J
Chemokine receptors as therapeutic targets in chronic obstructive pulmonary disease.
Trends in pharmacological sciences 2006;27(10):546-53.
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2006: Erin Edward M; Leaker Brian R; Nicholson Grant C; Tan Andrew J; Green Linda M; Neighbour Helen; Zacharasiewicz Angela S; Turner Jackie; Barnathan Elliot S; Kon Onn Min; Barnes Peter J; Hansel Trevor T
The effects of a monoclonal antibody directed against tumor necrosis factor-alpha in asthma.
American journal of respiratory and critical care medicine 2006;174(7):753-62.
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2006: Barnes Peter J
Transcription factors in airway diseases.
Laboratory investigation; a journal of technical methods and pathology 2006;86(9):867-72.
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2006: Catley Matthew C; Sukkar Maria B; Chung K Fan; Jaffee Bruce; Liao Sha-Mei; Coyle Anthony J; Haddad El-Bdaoui; Barnes Peter J; Newton Robert
Validation of the anti-inflammatory properties of small-molecule IkappaB Kinase (IKK)-2 inhibitors by comparison with adenoviral-mediated delivery of dominant-negative IKK1 and IKK2 in human airways smooth muscle.
Molecular pharmacology 2006;70(2):697-705.
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2006: Paraskakis Emmanouil; Brindicci Caterina; Fleming Louise; Krol Renata; Kharitonov Sergei A; Wilson Nicola M; Barnes Peter J; Bush Andrew
Measurement of bronchial and alveolar nitric oxide production in normal children and children with asthma.
American journal of respiratory and critical care medicine 2006;174(3):260-7.
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2006: Barnes Peter J
ABC of chronic obstructive pulmonary disease. Future treatments.
BMJ (Clinical research ed.) 2006;333(7561):246-8.
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2006: Hew Mark; Bhavsar Pankaj; Torrego Alfons; Meah Sally; Khorasani Nadia; Barnes Peter J; Adcock Ian; Chung Kian Fan
Relative corticosteroid insensitivity of peripheral blood mononuclear cells in severe asthma.
American journal of respiratory and critical care medicine 2006;174(2):134-41.
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2006: Barnes Peter J; Chowdhury Badrul; Kharitonov Sergei A; Magnussen Helgo; Page Clive P; Postma Dirkje; Saetta Marina
Pulmonary biomarkers in chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2006;174(1):6-14.
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2006: Hansel Trevor T; Benezet Olivier; Kafé Henri; Ponitz Hans-Hermann; Cheung David; Engelstätter Renate; Barnes Peter J
A multinational, 12-week, randomized study comparing the efficacy and tolerability of ciclesonide and budesonide in patients with asthma.
Clinical therapeutics 2006;28(6):906-20.
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2006: Barczyk Adam; Pierzchala Wladyslaw; Kon Onn M; Cosio Borja; Adcock Ian M; Barnes Peter J
Cytokine production by bronchoalveolar lavage T lymphocytes in chronic obstructive pulmonary disease.
The Journal of allergy and clinical immunology 2006;117(6):1484-92.
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2006: Barnes Peter J
How corticosteroids control inflammation: Quintiles Prize Lecture 2005.
British journal of pharmacology 2006;148(3):245-54.
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2006: Barnes Peter J
Receptor heterodimerization: a new level of cross-talk.
The Journal of clinical investigation 2006;116(5):1210-2.
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2006: Erin E M; Leaker B R; Zacharasiewicz A; Higgins L A; Nicholson G C; Boyce M J; de Boer P; Jones R C; Durham S R; Barnes P J; Hansel T T
Effects of a reversible beta-tryptase and trypsin inhibitor (RWJ-58643) on nasal allergic responses.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2006;36(4):458-64.
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2006: Barnes Peter J
Corticosteroids: the drugs to beat.
European journal of pharmacology 2006;533(1-3):2-14.
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2006: Barnes P J
Corticosteroid effects on cell signalling.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2006;27(2):413-26.
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2006: Barnes Peter J
Reduced histone deacetylase in COPD: clinical implications.
Chest 2006;129(1):151-5.
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2006: Barnes Peter J
Drugs for asthma.
British journal of pharmacology 2006;147 Suppl 1():S297-303.
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2006: Ito Kazuhiro; Yamamura Satoshi; Essilfie-Quaye Sarah; Cosio Borja; Ito Misako; Barnes Peter J; Adcock Ian M
Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression.
The Journal of experimental medicine 2006;203(1):7-13.
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2006: Lee Kang-Yun; Ito Kazuhiro; Hayashi Ryuji; Jazrawi Elen P I; Barnes Peter J; Adcock Ian M
NF-kappaB and activator protein 1 response elements and the role of histone modifications in IL-1beta-induced TGF-beta1 gene transcription.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(1):603-15.
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2006: Barnes Peter J
Novel signal transduction modulators for the treatment of airway diseases.
Pharmacology & therapeutics 2006;109(1-2):238-45.
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2006: Biddiscombe Martyn F; Barnes Peter J; Usmani Omar S
Generating monodisperse pharmacological aerosols using the spinning-top aerosol generator.
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 2006;19(3):245-53.
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2006: Moreno L; Perez-Vizcaino F; Harrington L; Faro R; Sturton G; Barnes P J; Mitchell J A
Pharmacology of airways and vessels in lung slices in situ: role of endogenous dilator hormones.
Respiratory research 2006;7():111.
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2006: Lex Christiane; Zacharasiewicz Angela; Payne Donald N R; Wilson Nicola M; Nicholson Andrew G; Kharitonov Sergei A; Barnes Peter J; Bush Andrew
Exhaled breath condensate cysteinyl leukotrienes and airway remodeling in childhood asthma: a pilot study.
Respiratory research 2006;7():63.
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2006: Rogers Duncan F; Barnes Peter J
Treatment of airway mucus hypersecretion.
Annals of medicine 2006;38(2):116-25.
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2006: Adcock Ian M; Ford Paul; Ito Kazuhiro; Barnes P J
Epigenetics and airways disease.
Respiratory research 2006;7():21.
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2005: Barnes Peter J
Emerging targets for COPD therapy.
Current drug targets. Inflammation and allergy 2005;4(6):675-83.
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2005: Adcock Ian M; Ito Kazuhiro; Barnes Peter J
Histone deacetylation: an important mechanism in inflammatory lung diseases.
COPD 2005;2(4):445-55.
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2005: Erin E M; Zacharasiewicz A S; Nicholson G C; Tan A J; Higgins L A; Williams T J; Murdoch R D; Durham S R; Barnes P J; Hansel T T
Topical corticosteroid inhibits interleukin-4, -5 and -13 in nasal secretions following allergen challenge.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2005;35(12):1608-14.
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2005: Barnes Peter J
Targeting histone deacetylase 2 in chronic obstructive pulmonary disease treatment.
Expert opinion on therapeutic targets 2005;9(6):1111-21.
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2005: Erin E M; Leaker B R; Zacharasiewicz A S; Higgins L A; Williams T J; Boyce M J; de Boer P; Durham S R; Barnes P J; Hansel T T
Single dose topical corticosteroid inhibits IL-5 and IL-13 in nasal lavage following grass pollen challenge.
Allergy 2005;60(12):1524-9.
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2005: Usmani Omar S; Biddiscombe Martyn F; Barnes Peter J
Regional lung deposition and bronchodilator response as a function of beta2-agonist particle size.
American journal of respiratory and critical care medicine 2005;172(12):1497-504.
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2005: Antczak Adam; Kharitonov Sergei A; Montuschi Paolo; Gorski Pawel; Barnes Peter J
Inflammatory response to sputum induction measured by exhaled markers.
Respiration; international review of thoracic diseases 2005;72(6):594-9.
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2005: Hansel Trevor T; Neighbour Helen; Erin Edward M; Tan Andrew J; Tennant Rachel C; Maus Joachim G; Barnes Peter J
Glycopyrrolate causes prolonged bronchoprotection and bronchodilatation in patients with asthma.
Chest 2005;128(4):1974-9.
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2005: Biernacki Wojciech A; Kharitonov Sergei A; Biernacka Helen M; Barnes Peter J
Effect of montelukast on exhaled leukotrienes and quality of life in asthmatic patients.
Chest 2005;128(4):1958-63.
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2005: Maneechotesuwan Kittipong; Essilfie-Quaye Sarah; Meah Sally; Kelly Claire; Kharitonov Sergei A; Adcock Ian M; Barnes Peter J
Formoterol attenuates neutrophilic airway inflammation in asthma.
Chest 2005;128(4):1936-42.
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2005: Basoglu Ozen K; Pelleg Amir; Essilfie-Quaye Sarah; Brindicci Caterina; Barnes Peter J; Kharitonov Sergei A
Effects of aerosolized adenosine 5'-triphosphate vs adenosine 5'-monophosphate on dyspnea and airway caliber in healthy nonsmokers and patients with asthma.
Chest 2005;128(4):1905-9.
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2005: Barnes Peter J
[How should clinical practice guidelines be implemented? Conclusion]
Revue de pneumologie clinique 2005;61(Spec no. 2):3S29-30.
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2005: Kharitonov Sergei A; Walker Lynda; Barnes Peter J
Repeatability of standardised nasal nitric oxide measurements in healthy and asthmatic adults and children.
Respiratory medicine 2005;99(9):1105-14.
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2005: Usmani Omar S; Ito Kazuhiro; Maneechotesuwan Kittipong; Ito Misako; Johnson Malcolm; Barnes Peter J; Adcock Ian M
Glucocorticoid receptor nuclear translocation in airway cells after inhaled combination therapy.
American journal of respiratory and critical care medicine 2005;172(6):704-12.
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2005: Sharma Rakesh; Bolger Aidan P; Rauchhaus Mathias; von Haehling Stephan; Doehner Wolfram; Adcock Ian M; Barnes Peter J; Poole-Wilson Philip A; Volk Hans-Dieter; Coats Andrew J S; Lim Sam; Anker Stefan D
Cellular endotoxin desensitization in patients with severe chronic heart failure.
European journal of heart failure : journal of the Working Group on Heart Failure of the European Society of Cardiology 2005;7(5):865-8.
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2005: Barnes Peter J
Molecular mechanisms and cellular effects of glucocorticosteroids.
Immunology and allergy clinics of North America 2005;25(3):451-68.
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2005: Barnes P J
Will it be steroids for ever?
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2005;35(7):843-5.
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2005: Brindicci C; Ito K; Resta O; Pride N B; Barnes P J; Kharitonov S A
Exhaled nitric oxide from lung periphery is increased in COPD.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2005;26(1):52-9.
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2005: Barnes P J; Stockley R A
COPD: current therapeutic interventions and future approaches.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2005;25(6):1084-106.
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2005: Culpitt S V; Rogers D F; Traves S L; Barnes P J; Donnelly L E
Sputum matrix metalloproteases: comparison between chronic obstructive pulmonary disease and asthma.
Respiratory medicine 2005;99(6):703-10.
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2005: Haque Rubaiyat A; Usmani Omar S; Barnes Peter J
Chronic idiopathic cough: a discrete clinical entity?
Chest 2005;127(5):1710-3.
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2005: Ito Kazuhiro; Ito Misako; Elliott W Mark; Cosio Borja; Caramori Gaetano; Kon Onn Min; Barczyk Adam; Hayashi Shizu; Adcock Ian M; Hogg James C; Barnes Peter J
Decreased histone deacetylase activity in chronic obstructive pulmonary disease.
The New England journal of medicine 2005;352(19):1967-76.
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2005: Wada Hiroo; Kagoshima Masahiko; Ito Kazuhiro; Barnes Peter J; Adcock Ian M
5-Azacytidine suppresses RNA polymerase II recruitment to the SLPI gene.
Biochemical and biophysical research communications 2005;331(1):93-9.
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2005: Birrell M A; McCluskie K; Wong S; Donnelly L E; Barnes P J; Belvisi M G
Resveratrol, an extract of red wine, inhibits lipopolysaccharide induced airway neutrophilia and inflammatory mediators through an NF-kappaB-independent mechanism.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(7):840-1.
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2005: Catley Matthew C; Chivers Joanna E; Holden Neil S; Barnes Peter J; Newton Robert
Validation of IKK beta as therapeutic target in airway inflammatory disease by adenoviral-mediated delivery of dominant-negative IKK beta to pulmonary epithelial cells.
British journal of pharmacology 2005;145(1):114-22.
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2005: Barnes P J; Adcock I M; Ito K
Histone acetylation and deacetylation: importance in inflammatory lung diseases.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2005;25(3):552-63.
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2005: Usmani Omar S; Belvisi Maria G; Patel Hema J; Crispino Natascia; Birrell Mark A; Korbonits Márta; Korbonits Dezso; Barnes Peter J
Theobromine inhibits sensory nerve activation and cough.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(2):231-3.
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2005: Adcock Ian M; Cosio Borja; Tsaprouni Loukia; Barnes Peter J; Ito Kazuhiro
Redox regulation of histone deacetylases and glucocorticoid-mediated inhibition of the inflammatory response.
Antioxidants & redox signaling 2005;7(1-2):144-52.
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2005: Barnes Peter J
Theophylline in chronic obstructive pulmonary disease: new horizons.
Proceedings of the American Thoracic Society 2005;2(4):334-9; discussion 340-1.
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2005: Barnes Peter J
Achieving asthma control.
Current medical research and opinion 2005;21 Suppl 4():S5-9.
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2005: Shahid Sukhbir K; Kharitonov Sergei A; Wilson Nicola M; Bush Andrew; Barnes Peter J
Exhaled 8-isoprostane in childhood asthma.
Respiratory research 2005;6():79.
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2005: Paredi Paolo; Kharitonov Sergei A; Barnes Peter J
Correlation of exhaled breath temperature with bronchial blood flow in asthma.
Respiratory research 2005;6():15.
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2004: Barnes Peter J
The role of anticholinergics in chronic obstructive pulmonary disease.
The American journal of medicine 2004;117 Suppl 12A():24S-32S.
-
2004: Barnes Peter J
Mediators of chronic obstructive pulmonary disease.
Pharmacological reviews 2004;56(4):515-48.
-
2004: Montuschi Paolo; Barnes Peter J; Roberts L Jackson
Isoprostanes: markers and mediators of oxidative stress.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(15):1791-800.
-
2004: Carpagnano G E; Kharitonov S A; Foschino-Barbaro M P; Resta O; Gramiccioni E; Barnes P J
Supplementary oxygen in healthy subjects and those with COPD increases oxidative stress and airway inflammation.
Thorax 2004;59(12):1016-9.
-
2004: Smith Susan J; Cieslinski Lenora B; Newton Robert; Donnelly Louise E; Fenwick Peter S; Nicholson Andrew G; Barnes Peter J; Barnette Mary S; Giembycz Mark A
Discovery of BRL 50481 [3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene], a selective inhibitor of phosphodiesterase 7: in vitro studies in human monocytes, lung macrophages, and CD8+ T-lymphocytes.
Molecular pharmacology 2004;66(6):1679-89.
-
2004: Barnes Peter J; Cosio Manuel G
Characterization of T lymphocytes in chronic obstructive pulmonary disease.
PLoS medicine 2004;1(1):e20.
-
2004: Barnes Peter J
The size of the problem of managing asthma.
Respiratory medicine 2004;98 Suppl B():S4-8.
-
2004: Chivers Joanna E; Cambridge Lisa M; Catley Matthew C; Mak Judith C; Donnelly Louise E; Barnes Peter J; Newton Robert
Differential effects of RU486 reveal distinct mechanisms for glucocorticoid repression of prostaglandin E release.
European journal of biochemistry / FEBS 2004;271(20):4042-52.
-
2004: Barnes Peter J
New drugs for asthma.
Nature reviews. Drug discovery 2004;3(10):831-44.
-
2004: Donnelly Louise E; Barnes Peter J
Acidic mammalian chitinase--a potential target for asthma therapy.
Trends in pharmacological sciences 2004;25(10):509-11.
-
2004: Donnelly Louise E; Newton Robert; Kennedy Gina E; Fenwick Peter S; Leung Rachel H F; Ito Kazuhiro; Russell Richard E K; Barnes Peter J
Anti-inflammatory effects of resveratrol in lung epithelial cells: molecular mechanisms.
American journal of physiology. Lung cellular and molecular physiology 2004;287(4):L774-83.
-
2004: Barnes Peter J; Hansel Trevor T
Prospects for new drugs for chronic obstructive pulmonary disease.
Lancet 2004;364(9438):985-96.
-
2004: Cosio Borja G; Tsaprouni Loukia; Ito Kazuhiro; Jazrawi Elen; Adcock Ian M; Barnes Peter J
Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages.
The Journal of experimental medicine 2004;200(5):689-95.
-
2004: Barnes Peter J; Kleinert Sabine
COPD--a neglected disease.
Lancet 2004;364(9434):564-5.
-
2004: Traves Suzanne L; Smith Susan J; Barnes Peter J; Donnelly Louise E
Specific CXC but not CC chemokines cause elevated monocyte migration in COPD: a role for CXCR2.
Journal of leukocyte biology 2004;76(2):441-50.
-
2004: Bucchioni E; Csoma Z; Allegra L; Chung K F; Barnes P J; Kharitonov S A
Adenosine 5'-monophosphate increases levels of leukotrienes in breath condensate in asthma.
Respiratory medicine 2004;98(7):651-5.
-
2004: Cosío Borja G; Mann Buphinder; Ito Kazuhiro; Jazrawi Elen; Barnes Peter J; Chung K Fan; Adcock Ian M
Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma.
American journal of respiratory and critical care medicine 2004;170(2):141-7.
-
2004: Barnes Peter J
Small airways in COPD.
The New England journal of medicine 2004;350(26):2635-7.
-
2004: Matthews John G; Ito Kazuhiro; Barnes Peter J; Adcock Ian M
Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients.
The Journal of allergy and clinical immunology 2004;113(6):1100-8.
-
2004: Leckie M J; Gomma A H; Purcell I F; Nyawo B; Dewar A; Okrongly D; Burman J F; Hooper J; Barnes P J; Clague J R; Hansel Trevor T
Automated quantitation of peripheral blood neutrophil activation in patients with myocardial ischaemia.
International journal of cardiology 2004;95(2-3):307-13.
-
2004: Atzori L; Caramori G; Lim S; Jazrawi E; Donnelly L; Adcock I; Barnes P J; Chung K F
Effect of cigarette smoking on haem-oxygenase expression in alveolar macrophages.
Respiratory medicine 2004;98(6):530-5.
-
2004: Carpagnano Giovanna E; Barnes Peter J; Francis Jackie; Wilson Nicola; Bush Andrew; Kharitonov Sergei A
Breath condensate pH in children with cystic fibrosis and asthma: a new noninvasive marker of airway inflammation?
Chest 2004;125(6):2005-10.
-
2004: Barnes Peter J
COPD: is there light at the end of the tunnel?
Current opinion in pharmacology 2004;4(3):263-72.
-
2004: Lim S; Caramori G; Tomita K; Jazrawi E; Oates T; Chung K F; Barnes P J; Adcock I M
Differential expression of IL-10 receptor by epithelial cells and alveolar macrophages.
Allergy 2004;59(5):505-14.
-
2004: Meja Koremu K; Catley Matthew C; Cambridge Lisa M; Barnes Peter J; Lum Hazel; Newton Robert; Giembycz Mark A
Adenovirus-mediated delivery and expression of a cAMP-dependent protein kinase inhibitor gene to BEAS-2B epithelial cells abolishes the anti-inflammatory effects of rolipram, salbutamol, and prostaglandin E2: a comparison with H-89.
The Journal of pharmacology and experimental therapeutics 2004;309(2):833-44.
-
2004: Barnes Peter J
Alveolar macrophages as orchestrators of COPD.
COPD 2004;1(1):59-70.
-
2004: Barnes Peter J
Asthma guidelines: recommendations versus reality.
Respiratory medicine 2004;98 Suppl A():S1-7.
-
2004: Bergmann Martin W; Staples Karl J; Barnes Peter J; Newton Robert
Nuclear factor-kappaB does not mediate the inhibitory effects of dexamethasone on granulocyte-macrophage colony-stimulating factor expression.
Immunology 2004;111(4):430-4.
-
2004: Catley Matthew C; Cambridge Lisa M; Nasuhara Yasuyuki; Ito Kazuhiro; Chivers Joanna E; Beaton Andrew; Holden Neil S; Bergmann Martin W; Barnes Peter J; Newton Robert
Inhibitors of protein kinase C (PKC) prevent activated transcription: role of events downstream of NF-kappaB DNA binding.
The Journal of biological chemistry 2004;279(18):18457-66.
-
2004: Bergmann Martin W; Staples Karl J; Smith Susan J; Barnes Peter J; Newton Robert
Glucocorticoid inhibition of granulocyte macrophage-colony-stimulating factor from T cells is independent of control by nuclear factor-kappaB and conserved lymphokine element 0.
American journal of respiratory cell and molecular biology 2004;30(4):555-63.
-
2004: Koch Andrea; Giembycz Mark; Ito Kazuhiro; Lim Sam; Jazrawi Elen; Barnes Peter J; Adcock Ian; Erdmann Erland; Chung K Fan
Mitogen-activated protein kinase modulation of nuclear factor-kappaB-induced granulocyte macrophage-colony-stimulating factor release from human alveolar macrophages.
American journal of respiratory cell and molecular biology 2004;30(3):342-9.
-
2004: Ito K; Hanazawa T; Tomita K; Barnes P J; Adcock I M
Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: role of tyrosine nitration.
Biochemical and biophysical research communications 2004;315(1):240-5.
-
2004: Barnes Peter J; Ito Kazuhiro; Adcock Ian M
Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase.
Lancet 2004;363(9410):731-3.
-
2004: Holden Neil S; Catley Matthew C; Cambridge Lisa M; Barnes Peter J; Newton Robert
ICAM-1 expression is highly NF-kappaB-dependent in A549 cells. No role for ERK and p38 MAPK.
European journal of biochemistry / FEBS 2004;271(4):785-91.
-
2004: Hansel Trevor T; Tennant Rachel C; Tan Andrew J; Higgins Lorna A; Neighbour Helen; Erin Edward M; Barnes Peter J
Theophylline: mechanism of action and use in asthma and chronic obstructive pulmonary disease.
Drugs of today (Barcelona, Spain : 1998) 2004;40(1):55-69.
-
2004: Usmani Omar S; Biddiscombe Martyn F; Underwood S Richard; Barnes Peter J
Characterization of the generation of radiolabeled monodisperse albuterol particles using the spinning-top aerosol generator.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(1):69-73.
-
2004: Barnes Peter J
Distribution of receptor targets in the lung.
Proceedings of the American Thoracic Society 2004;1(4):345-51.
-
2004: Barnes Peter J
Corticosteroid resistance in airway disease.
Proceedings of the American Thoracic Society 2004;1(3):264-8.
-
2004: Adcock Ian M; Ito Kaz; Barnes Peter J
Glucocorticoids: effects on gene transcription.
Proceedings of the American Thoracic Society 2004;1(3):247-54.
-
2004: Kharitonov Sergei A; Barnes Peter J
Effects of corticosteroids on noninvasive biomarkers of inflammation in asthma and chronic obstructive pulmonary disease.
Proceedings of the American Thoracic Society 2004;1(3):191-9.
-
2004: Kankaanranta Hannu; Lahdensuo Aarne; Moilanen Eeva; Barnes Peter J
Add-on therapy options in asthma not adequately controlled by inhaled corticosteroids: a comprehensive review.
Respiratory research 2004;5():17.
-
2003: Bucchioni Enrica; Kharitonov Sergei A; Allegra Luigi; Barnes Peter J
High levels of interleukin-6 in the exhaled breath condensate of patients with COPD.
Respiratory medicine 2003;97(12):1299-302.
-
2003: Barnes Peter J
Cytokine-directed therapies for the treatment of chronic airway diseases.
Cytokine & growth factor reviews 2003;14(6):511-22.
-
2003: Culpitt S V; Rogers D F; Fenwick P S; Shah P; De Matos C; Russell R E K; Barnes P J; Donnelly L E
Inhibition by red wine extract, resveratrol, of cytokine release by alveolar macrophages in COPD.
Thorax 2003;58(11):942-6.
-
2003: Usmani Omar S; Biddiscombe Martyn F; Nightingale Julia A; Underwood S Richard; Barnes Peter J
Effects of bronchodilator particle size in asthmatic patients using monodisperse aerosols.
Journal of applied physiology (Bethesda, Md. : 1985) 2003;95(5):2106-12.
-
2003: Barnes P J; Shapiro S D; Pauwels R A
Chronic obstructive pulmonary disease: molecular and cellular mechanisms.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2003;22(4):672-88.
-
2003: Carpagnano Giovanna E; Kharitonov Sergei A; Resta Onofrio; Foschino-Barbaro Maria P; Gramiccioni Enzo; Barnes Peter J
8-Isoprostane, a marker of oxidative stress, is increased in exhaled breath condensate of patients with obstructive sleep apnea after night and is reduced by continuous positive airway pressure therapy.
Chest 2003;124(4):1386-92.
-
2003: Robinson D S; Campbell D A; Durham S R; Pfeffer J; Barnes P J; Chung K F;
Systematic assessment of difficult-to-treat asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2003;22(3):478-83.
-
2003: Patel Hema J; Birrell Mark A; Crispino Natascia; Hele David J; Venkatesan Priya; Barnes Peter J; Yacoub Magdi H; Belvisi Maria G
Inhibition of guinea-pig and human sensory nerve activity and the cough reflex in guinea-pigs by cannabinoid (CB2) receptor activation.
British journal of pharmacology 2003;140(2):261-8.
-
2003: Barnes Peter J; Adcock Ian M
How do corticosteroids work in asthma?
Annals of internal medicine 2003;139(5 Pt 1):359-70.
-
2003: Barnes P J
Chronic obstructive pulmonary disease * 12: New treatments for COPD.
Thorax 2003;58(9):803-8.
-
2003: Csoma Zsuzsanna; Bush Andrew; Wilson Nicola M; Donnelly Louise; Balint Beatrix; Barnes Peter J; Kharitonov Sergei A
Nitric oxide metabolites are not reduced in exhaled breath condensate of patients with primary ciliary dyskinesia.
Chest 2003;124(2):633-8.
-
2003: Staples Karl J; Bergmann Martin W; Barnes Peter J; Newton Robert
Evidence for post-transcriptional regulation of interleukin-5 by dexamethasone.
Immunology 2003;109(4):527-35.
-
2003: Catley Matthew C; Chivers Joanna E; Cambridge Lisa M; Holden Neil; Slater Donna M; Staples Karl J; Bergmann Martin W; Loser Peter; Barnes Peter J; Newton Robert
IL-1beta-dependent activation of NF-kappaB mediates PGE2 release via the expression of cyclooxygenase-2 and microsomal prostaglandin E synthase.
FEBS letters 2003;547(1-3):75-9.
-
2003: Zhang Xianzhi; Msc; Moilanen Eeva; Lahti Aleksi; Hämäläinen Mari; Giembycz Mark A; Barnes Peter J; Lindsay Mark A; Kankaanranta Hannu
Regulation of eosinophil apoptosis by nitric oxide: Role of c-Jun-N-terminal kinase and signal transducer and activator of transcription 5.
The Journal of allergy and clinical immunology 2003;112(1):93-101.
-
2003: Montuschi P; Kharitonov S A; Ciabattoni G; Barnes P J
Exhaled leukotrienes and prostaglandins in COPD.
Thorax 2003;58(7):585-8.
-
2003: Hansel Trevor T; Kharitonov Sergei A; Donnelly Louise E; Erin Edward M; Currie Mark G; Moore William M; Manning Pamela T; Recker David P; Barnes Peter J
A selective inhibitor of inducible nitric oxide synthase inhibits exhaled breath nitric oxide in healthy volunteers and asthmatics.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(10):1298-300.
-
2003: Tennant Rachel C; Erin Edward M; Barnes Peter J; Hansel Trevor T
Long-acting beta 2-adrenoceptor agonists or tiotropium bromide for patients with COPD: is combination therapy justified?
Current opinion in pharmacology 2003;3(3):270-6.
-
2003: Barnes Peter J
Anti-leukotrienes: here to stay?
Current opinion in pharmacology 2003;3(3):257-63.
-
2003: Nabeyrat Elodie; Jones Gina E; Fenwick Peter S; Barnes Peter J; Donnelly Louise E
Mitogen-activated protein kinases mediate peroxynitrite-induced cell death in human bronchial epithelial cells.
American journal of physiology. Lung cellular and molecular physiology 2003;284(6):L1112-20.
-
2003: Carpagnano G E; Kharitonov S A; Foschino-Barbaro M P; Resta O; Gramiccioni E; Barnes P J
Increased inflammatory markers in the exhaled breath condensate of cigarette smokers.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2003;21(4):589-93.
-
2003: Beeh Kai M; Kornmann Oliver; Buhl Roland; Culpitt Sarah V; Giembycz Mark A; Barnes Peter J
Neutrophil chemotactic activity of sputum from patients with COPD: role of interleukin 8 and leukotriene B4.
Chest 2003;123(4):1240-7.
-
2003: Carpagnano Giovanna E; Barnes Peter J; Geddes Duncan M; Hodson Margaret E; Kharitonov Sergei A
Increased leukotriene B4 and interleukin-6 in exhaled breath condensate in cystic fibrosis.
American journal of respiratory and critical care medicine 2003;167(8):1109-12.
-
2003: Biernacki W A; Kharitonov S A; Barnes P J
Increased leukotriene B4 and 8-isoprostane in exhaled breath condensate of patients with exacerbations of COPD.
Thorax 2003;58(4):294-8.
-
2003: Carpagnano G E; Kharitonov S A; Wells A U; Pantelidis P; Du Bois R M; Barnes P J
Increased vitronectin and endothelin-1 in the breath condensate of patients with fibrosing lung disease.
Respiration; international review of thoracic diseases 2003;70(2):154-60.
-
2003: Paredi P; Caramori G; Cramer D; Ward S; Ciaccia A; Papi A; Kharitonov S A; Barnes P J
Slower rise of exhaled breath temperature in chronic obstructive pulmonary disease.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2003;21(3):439-43.
-
2003: Kharitonov S A; Gonio F; Kelly C; Meah S; Barnes P J
Reproducibility of exhaled nitric oxide measurements in healthy and asthmatic adults and children.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2003;21(3):433-8.
-
2003: Barnes Peter J
Theophylline: new perspectives for an old drug.
American journal of respiratory and critical care medicine 2003;167(6):813-8.
-
2003: Biddiscombe Martyn F; Usmani Omar S; Barnes Peter J
A system for the production and delivery of monodisperse salbutamol aerosols to the lungs.
International journal of pharmaceutics 2003;254(2):243-53.
-
2003: Kharitonov Sergei A; Barnes Peter J
Nitric oxide, nitrotyrosine, and nitric oxide modulators in asthma and chronic obstructive pulmonary disease.
Current allergy and asthma reports 2003;3(2):121-9.
-
2003: Tomita K; Barnes P J; Adcock I M
The effect of oxidative stress on histone acetylation and IL-8 release.
Biochemical and biophysical research communications 2003;301(2):572-7.
-
2003: Smith Susan J; Brookes-Fazakerley Steven; Donnelly Louise E; Barnes Peter J; Barnette Mary S; Giembycz Mark A
Ubiquitous expression of phosphodiesterase 7A in human proinflammatory and immune cells.
American journal of physiology. Lung cellular and molecular physiology 2003;284(2):L279-89.
-
2003: Barnes Peter J
Update on asthma.
The Israel Medical Association journal : IMAJ 2003;5(1):68-72.
-
2003: Wodehouse T; Kharitonov S A; Mackay I S; Barnes P J; Wilson R; Cole P J
Nasal nitric oxide measurements for the screening of primary ciliary dyskinesia.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2003;21(1):43-7.
-
2003: Horváth I; Loukides S; Wodehouse T; Csiszér E; Cole P J; Kharitonov S A; Barnes P J
Comparison of exhaled and nasal nitric oxide and exhaled carbon monoxide levels in bronchiectatic patients with and without primary ciliary dyskinesia.
Thorax 2003;58(1):68-72.
-
2003: Leckie M J; Jenkins G R; Khan J; Smith S J; Walker C; Barnes P J; Hansel T T
Sputum T lymphocytes in asthma, COPD and healthy subjects have the phenotype of activated intraepithelial T cells (CD69+ CD103+).
Thorax 2003;58(1):23-9.
-
2003: Barnes Peter J
Therapy of chronic obstructive pulmonary disease.
Pharmacology & therapeutics 2003;97(1):87-94.
-
2003: Culpitt Sarah V; Rogers Duncan F; Shah Pallav; De Matos Carmen; Russell Richard E K; Donnelly Louise E; Barnes Peter J
Impaired inhibition by dexamethasone of cytokine release by alveolar macrophages from patients with chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2003;167(1):24-31.
-
2003: Barnes Peter J
New treatments for chronic obstructive pulmonary disease.
Annali dell'Istituto superiore di sanità 2003;39(4):573-82.
-
2003: Barnes Peter J
New concepts in chronic obstructive pulmonary disease.
Annual review of medicine 2003;54():113-29.
-
2002: Paredi Paolo; Kharitonov Sergei A; Barnes Peter J
Analysis of expired air for oxidation products.
American journal of respiratory and critical care medicine 2002;166(12 Pt 2):S31-7.
-
2002: Mattos Waldo; Lim Sam; Russell Richard; Jatakanon Anon; Chung K Fan; Barnes Peter J
Matrix metalloproteinase-9 expression in asthma: effect of asthma severity, allergen challenge, and inhaled corticosteroids.
Chest 2002;122(5):1543-52.
-
2002: Montuschi Paolo; Nightingale Julia A; Kharitonov Sergei A; Barnes Peter J
Ozone-induced increase in exhaled 8-isoprostane in healthy subjects is resistant to inhaled budesonide.
Free radical biology & medicine 2002;33(10):1403-8.
-
2002: Csoma Zsuzsanna; Kharitonov Sergei A; Balint Beatrix; Bush Andrew; Wilson Nicola M; Barnes Peter J
Increased leukotrienes in exhaled breath condensate in childhood asthma.
American journal of respiratory and critical care medicine 2002;166(10):1345-9.
-
2002: Carpagnano Giovanna E; Kharitonov Sergei A; Resta Onofrio; Foschino-Barbaro Maria P; Gramiccioni Enzo; Barnes Peter J
Increased 8-isoprostane and interleukin-6 in breath condensate of obstructive sleep apnea patients.
Chest 2002;122(4):1162-7.
-
2002: Kharitonov S A; Donnelly L E; Montuschi P; Corradi M; Collins J V; Barnes P J
Dose-dependent onset and cessation of action of inhaled budesonide on exhaled nitric oxide and symptoms in mild asthma.
Thorax 2002;57(10):889-96.
-
2002: Russell Richard E K; Thorley Andrew; Culpitt Sarah V; Dodd Sara; Donnelly Louise E; Demattos Carmen; Fitzgerald Mary; Barnes Peter J
Alveolar macrophage-mediated elastolysis: roles of matrix metalloproteinases, cysteine, and serine proteases.
American journal of physiology. Lung cellular and molecular physiology 2002;283(4):L867-73.
-
2002: Hansel Trevor T; Barnes Peter J
Tiotropium bromide: a novel once-daily anticholinergic bronchodilator for the treatment of COPD.
Drugs of today (Barcelona, Spain : 1998) 2002;38(9):585-600.
-
2002: Eynott Paul R; Groneberg David A; Caramori Gaetano; Adcock Ian M; Donnelly Louise E; Kharitonov Sergei; Barnes Peter J; Chung K Fan
Role of nitric oxide in allergic inflammation and bronchial hyperresponsiveness.
European journal of pharmacology 2002;452(1):123-33.
-
2002: Tomita Katsuyuki; Caramori Gaetano; Lim Sam; Ito Kazuhiro; Hanazawa Toyoyuki; Oates Timothy; Chiselita Irena; Jazrawi Elen; Chung K Fan; Barnes Peter J; Adcock Ian M
Increased p21(CIP1/WAF1) and B cell lymphoma leukemia-x(L) expression and reduced apoptosis in alveolar macrophages from smokers.
American journal of respiratory and critical care medicine 2002;166(5):724-31.
-
2002: Ito Kazuhiro; Caramori Gaetano; Lim Sam; Oates Tim; Chung K Fan; Barnes Peter J; Adcock Ian M
Expression and activity of histone deacetylases in human asthmatic airways.
American journal of respiratory and critical care medicine 2002;166(3):392-6.
-
2002: Antczak Adam; Montuschi Paolo; Kharitonov Sergei; Gorski Pawel; Barnes Peter J
Increased exhaled cysteinyl-leukotrienes and 8-isoprostane in aspirin-induced asthma.
American journal of respiratory and critical care medicine 2002;166(3):301-6.
-
2002: Traves S L; Culpitt S V; Russell R E K; Barnes P J; Donnelly L E
Increased levels of the chemokines GROalpha and MCP-1 in sputum samples from patients with COPD.
Thorax 2002;57(7):590-5.
-
2002: Erin E M; Williams T J; Barnes P J; Hansel T T
Eotaxin receptor (CCR3) antagonism in asthma and allergic disease.
Current drug targets. Inflammation and allergy 2002;1(2):201-14.
-
2002: Barnes Peter J
New treatments for COPD.
Nature reviews. Drug discovery 2002;1(6):437-46.
-
2002: Ito Kazuhiro; Lim Sam; Caramori Gaetano; Cosio Borja; Chung K Fan; Adcock Ian M; Barnes Peter J
A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(13):8921-6.
-
2002: Bryan Shannon A; Jose Peter J; Topping Joanna R; Wilhelm Robert; Soderberg Carol; Kertesz Denis; Barnes Peter J; Williams Timothy J; Hansel Trevor T; Sabroe Ian
Responses of leukocytes to chemokines in whole blood and their antagonism by novel CC-chemokine receptor 3 antagonists.
American journal of respiratory and critical care medicine 2002;165(12):1602-9.
-
2002: Birrell Mark A; Crispino Natascia; Hele David J; Patel Hema J; Yacoub Magdi H; Barnes Peter J; Belvisi Maria G
Effect of dopamine receptor agonists on sensory nerve activity: possible therapeutic targets for the treatment of asthma and COPD.
British journal of pharmacology 2002;136(4):620-8.
-
2002: Culpitt Sarah V; de Matos Carmen; Russell Richard E; Donnelly Louise E; Rogers Duncan F; Barnes Peter J
Effect of theophylline on induced sputum inflammatory indices and neutrophil chemotaxis in chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2002;165(10):1371-6.
-
2002: Nightingale Julia A; Rogers Duncan F; Barnes Peter J
Comparison of the effects of salmeterol and formoterol in patients with severe asthma.
Chest 2002;121(5):1401-6.
-
2002: Shahid Sukhbir K; Kharitonov Sergei A; Wilson Nicola M; Bush Andrew; Barnes Peter J
Increased interleukin-4 and decreased interferon-gamma in exhaled breath condensate of children with asthma.
American journal of respiratory and critical care medicine 2002;165(9):1290-3.
-
2002: Russell Richard E K; Culpitt Sarah V; DeMatos Carmen; Donnelly Louise; Smith Michael; Wiggins John; Barnes Peter J
Release and activity of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 by alveolar macrophages from patients with chronic obstructive pulmonary disease.
American journal of respiratory cell and molecular biology 2002;26(5):602-9.
-
2002: De Souza Patricia M; Kankaanranta Hannu; Michael Ashour; Barnes Peter J; Giembycz Mark A; Lindsay Mark A
Caspase-catalyzed cleavage and activation of Mst1 correlates with eosinophil but not neutrophil apoptosis.
Blood 2002;99(9):3432-8.
-
2002: Irusen Elvis; Matthews John G; Takahashi Atsushi; Barnes Peter J; Chung Kian F; Adcock Ian M
p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma.
The Journal of allergy and clinical immunology 2002;109(4):649-57.
-
2002: Montuschi Paolo; Barnes Peter J
Exhaled leukotrienes and prostaglandins in asthma.
The Journal of allergy and clinical immunology 2002;109(4):615-20.
-
2002: Tomita Katsuyuki; Lim Sam; Hanazawa Toyoyuki; Usmani Omar; Stirling Rob; Chung K Fan; Barnes Peter J; Adcock Ian M
Attenuated production of intracellular IL-10 and IL-12 in monocytes from patients with severe asthma.
Clinical immunology (Orlando, Fla.) 2002;102(3):258-66.
-
2002: Mak Judith C W; Hisada Takeshi; Salmon Michael; Barnes Peter J; Chung K Fan
Glucocorticoids reverse IL-1beta-induced impairment of beta-adrenoceptor-mediated relaxation and up-regulation of G-protein-coupled receptor kinases.
British journal of pharmacology 2002;135(4):987-96.
-
2002: Mak Judith C W; Chuang Tsu Tshen; Harris Carol A; Barnes Peter J
Increased expression of G protein-coupled receptor kinases in cystic fibrosis lung.
European journal of pharmacology 2002;436(3):165-72.
-
2002: Kharitonov Sergei A; Barnes Peter J
Biomarkers of some pulmonary diseases in exhaled breath.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2002;7(1):1-32.
-
2002: Kankaanranta Hannu; Giembycz Mark A; Barnes Peter J; Haddad El-Bdaoui; Saarelainen Seppo; Zhang Xianzhi; Moilanen Eeva; Lindsay Mark A
Hydrogen peroxide reverses IL-5 afforded eosinophil survival and promotes constitutive human eosinophil apoptosis.
International archives of allergy and immunology 2002;127(1):73-8.
-
2002: Barnes P J
Scientific rationale for inhaled combination therapy with long-acting beta2-agonists and corticosteroids.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2002;19(1):182-91.
-
2002: Paredi Paolo; Kharitonov Sergei A; Barnes Peter J
Faster rise of exhaled breath temperature in asthma: a novel marker of airway inflammation?
American journal of respiratory and critical care medicine 2002;165(2):181-4.
-
2002: Donnelly Louise E; Barnes Peter J
Expression and regulation of inducible nitric oxide synthase from human primary airway epithelial cells.
American journal of respiratory cell and molecular biology 2002;26(1):144-51.
-
2002: Barnes Peter J
Current and future therapies for airway mucus hypersecretion.
Novartis Foundation symposium 2002;248():237-49; discussion 249-53, 277-82.
-
2002: Barnes Peter J
Cytokine modulators as novel therapies for asthma.
Annual review of pharmacology and toxicology 2002;42():81-98.
-
2001: Barnes P J
Cytokine modulators for allergic diseases.
Current opinion in allergy and clinical immunology 2001;1(6):555-60.
-
2001: Biernacki W A; Kharitonov S A; Barnes P J
Exhaled carbon monoxide in patients with lower respiratory tract infection.
Respiratory medicine 2001;95(12):1003-5.
-
2001: van Rensen E L; Stirling R G; Scheerens J; Staples K; Sterk P J; Barnes P J; Chung K F
Evidence for systemic rather than pulmonary effects of interleukin-5 administration in asthma.
Thorax 2001;56(12):935-40.
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2001: Stirling R G; van Rensen E L; Barnes P J; Chung K F
Interleukin-5 induces CD34(+) eosinophil progenitor mobilization and eosinophil CCR3 expression in asthma.
American journal of respiratory and critical care medicine 2001;164(8 Pt 1):1403-9.
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2001: O'Byrne P M; Barnes P J; Rodriguez-Roisin R; Runnerstrom E; Sandstrom T; Svensson K; Tattersfield A
Low dose inhaled budesonide and formoterol in mild persistent asthma: the OPTIMA randomized trial.
American journal of respiratory and critical care medicine 2001;164(8 Pt 1):1392-7.
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2001: Kagoshima M; Wilcke T; Ito K; Tsaprouni L; Barnes P J; Punchard N; Adcock I M
Glucocorticoid-mediated transrepression is regulated by histone acetylation and DNA methylation.
European journal of pharmacology 2001;429(1-3):327-34.
-
2001: Lynch O T; Giembycz M A; Barnes P J; Lindsay M A
Pharmacological comparison of LTB(4)-induced NADPH oxidase activation in adherent and non-adherent guinea-pig eosinophils.
British journal of pharmacology 2001;134(4):797-806.
-
2001: Barnes P J
Molecular mechanisms of corticosteroids in allergic diseases.
Allergy 2001;56(10):928-36.
-
2001: Caramori G; Lim S; Ito K; Tomita K; Oates T; Jazrawi E; Chung K F; Barnes P J; Adcock I M
Expression of GATA family of transcription factors in T-cells, monocytes and bronchial biopsies.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2001;18(3):466-73.
-
2001: Newton R; Staples K J; Hart L; Barnes P J; Bergmann M W
GM-CSF expression in pulmonary epithelial cells is regulated negatively by posttranscriptional mechanisms.
Biochemical and biophysical research communications 2001;287(1):249-53.
-
2001: Barnes P J
Clinical outcome of adding long-acting beta-agonists to inhaled corticosteroids.
Respiratory medicine 2001;95 Suppl B():S12-6.
-
2001: Montuschi P; Kharitonov S A; Barnes P J
Exhaled carbon monoxide and nitric oxide in COPD.
Chest 2001;120(2):496-501.
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2001: Spicuzza L; Belvisi M G; Birrell M A; Barnes P J; Hele D J; Giembycz M A
Evidence that the anti-spasmogenic effect of the beta-adrenoceptor agonist, isoprenaline, on guinea-pig trachealis is not mediated by cyclic AMP-dependent protein kinase.
British journal of pharmacology 2001;133(8):1201-12.
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2001: Staples K J; Bergmann M; Tomita K; Houslay M D; McPhee I; Barnes P J; Giembycz M A; Newton R
Adenosine 3',5'-cyclic monophosphate (cAMP)-dependent inhibition of IL-5 from human T lymphocytes is not mediated by the cAMP-dependent protein kinase A.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(4):2074-80.
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2001: Ito K; Jazrawi E; Cosio B; Barnes P J; Adcock I M
p65-activated histone acetyltransferase activity is repressed by glucocorticoids: mifepristone fails to recruit HDAC2 to the p65-HAT complex.
The Journal of biological chemistry 2001;276(32):30208-15.
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2001: Lim S; Tomita K; Caramori G; Jatakanon A; Oliver B; Keller A; Adcock I; Chung K F; Barnes P J;
Low-dose theophylline reduces eosinophilic inflammation but not exhaled nitric oxide in mild asthma.
American journal of respiratory and critical care medicine 2001;164(2):273-6.
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2001: Kharitonov S A; Barnes P J
Exhaled markers of inflammation.
Current opinion in allergy and clinical immunology 2001;1(3):217-24.
-
2001: Barnes P J
New treatments for chronic obstructive pulmonary disease.
Current opinion in pharmacology 2001;1(3):217-22.
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2001: Balint B; Kharitonov S A; Hanazawa T; Donnelly L E; Shah P L; Hodson M E; Barnes P J
Increased nitrotyrosine in exhaled breath condensate in cystic fibrosis.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2001;17(6):1201-7.
-
2001: Robinson D S; Campbell D; Barnes P J
Addition of leukotriene antagonists to therapy in chronic persistent asthma: a randomised double-blind placebo-controlled trial.
Lancet 2001;357(9273):2007-11.
-
2001: Andersson F; Stahl E; Barnes P J; Löfdahl C G; O'Byrne P M; Pauwels R A; Postma D S; Tattersfield A E; Ullman A;
Adding formoterol to budesonide in moderate asthma--health economic results from the FACET study.
Respiratory medicine 2001;95(6):505-12.
-
2001: Kharitonov S A; Barnes P J
Exhaled markers of pulmonary disease.
American journal of respiratory and critical care medicine 2001;163(7):1693-722.
-
2001: Balint B; Donnelly L E; Hanazawa T; Kharitonov S A; Barnes P J
Increased nitric oxide metabolites in exhaled breath condensate after exposure to tobacco smoke.
Thorax 2001;56(6):456-61.
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2001: Ito K; Lim S; Caramori G; Chung K F; Barnes P J; Adcock I M
Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(6):1110-2.
-
2001: Barnes P J
Tiotropium bromide.
Expert opinion on investigational drugs 2001;10(4):733-40.
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2001: Hansel T T; Barnes P J
Novel drugs for treating asthma.
Current allergy and asthma reports 2001;1(2):164-73.
-
2001: Spicuzza L; Barnes P J; Di Maria G U; Belvisi M G
Effect of 8-iso-prostaglandin F(2 alpha) on acetylcholine release from parasympathetic nerves in guinea pig airways.
European journal of pharmacology 2001;416(3):231-4.
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2001: Corradi M; Montuschi P; Donnelly L E; Pesci A; Kharitonov S A; Barnes P J
Increased nitrosothiols in exhaled breath condensate in inflammatory airway diseases.
American journal of respiratory and critical care medicine 2001;163(4):854-8.
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2001: Finney P A; Donnelly L E; Belvisi M G; Chuang T T; Birrell M; Harris A; Mak J C; Scorer C; Barnes P J; Adcock I M; Giembycz M A
Chronic systemic administration of salmeterol to rats promotes pulmonary beta(2)-adrenoceptor desensitization and down-regulation of G(s alpha).
British journal of pharmacology 2001;132(6):1261-70.
-
2001: Donnelly L E; Barnes P J
Expression of heme oxygenase in human airway epithelial cells.
American journal of respiratory cell and molecular biology 2001;24(3):295-303.
-
2001: Barnes P J
Neurogenic inflammation in the airways.
Respiration physiology 2001;125(1-2):145-54.
-
2001: Barnes P J
Corticosteroids, IgE, and atopy.
The Journal of clinical investigation 2001;107(3):265-6.
-
2001: Paredi P; Kharitonov S A; Hanazawa T; Barnes P J
Local vasodilator response to mobile phones.
The Laryngoscope 2001;111(1):159-62.
-
2001: Barnes P J
Future Advances in COPD Therapy.
Respiration; international review of thoracic diseases 2001;68(5):441-8.
-
2001: Barnes P J
Th2 cytokines and asthma: an introduction.
Respiratory research 2001;2(2):64-5.
-
2001: Barnes P J
Histamine and serotonin.
Pulmonary pharmacology & therapeutics 2001;14(5):329-39.
-
2001: Barnes P J
Potential novel therapies for chronic obstructive pulmonary disease.
Novartis Foundation symposium 2001;234():255-67; discussion 267-72.
-
2000: Bryan S A; O'Connor B J; Matti S; Leckie M J; Kanabar V; Khan J; Warrington S J; Renzetti L; Rames A; Bock J A; Boyce M J; Hansel T T; Holgate S T; Barnes P J
Effects of recombinant human interleukin-12 on eosinophils, airway hyper-responsiveness, and the late asthmatic response.
Lancet 2000;356(9248):2149-53.
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2000: Leckie M J; ten Brinke A; Khan J; Diamant Z; O'Connor B J; Walls C M; Mathur A K; Cowley H C; Chung K F; Djukanovic R; Hansel T T; Holgate S T; Sterk P J; Barnes P J
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response.
Lancet 2000;356(9248):2144-8.
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2000: Mak J C; Rousell J; Haddad E B; Barnes P J
Transforming growth factor-beta1 inhibits beta2-adrenoceptor gene transcription.
Naunyn-Schmiedeberg's archives of pharmacology 2000;362(6):520-5.
-
2000: Barnes P J
Anti-IgE therapy in asthma: rationale and therapeutic potential.
International archives of allergy and immunology 2000;123(3):196-204.
-
2000: Meja K K; Seldon P M; Nasuhara Y; Ito K; Barnes P J; Lindsay M A; Giembycz M A
p38 MAP kinase and MKK-1 co-operate in the generation of GM-CSF from LPS-stimulated human monocytes by an NF-kappa B-independent mechanism.
British journal of pharmacology 2000;131(6):1143-53.
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2000: Lim S; Groneberg D; Fischer A; Oates T; Caramori G; Mattos W; Adcock I; Barnes P J; Chung K F
Expression of heme oxygenase isoenzymes 1 and 2 in normal and asthmatic airways: effect of inhaled corticosteroids.
American journal of respiratory and critical care medicine 2000;162(5):1912-8.
-
2000: Newton R; Hart L; Chung K F; Barnes P J
Ceramide induction of COX-2 and PGE(2) in pulmonary A549 cells does not involve activation of NF-kappaB.
Biochemical and biophysical research communications 2000;277(3):675-9.
-
2000: Koch A; Nasuhara Y; Barnes P J; Lindsay M A; Giembycz M A
Extracellular signal-regulated kinase 1/2 control Ca(2+)-independent force development in histamine-stimulated bovine tracheal smooth muscle.
British journal of pharmacology 2000;131(5):981-9.
-
2000: Kharitonov S A; Barnes P J
Clinical aspects of exhaled nitric oxide.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2000;16(4):781-92.
-
2000: Paredi P; Kharitonov S A; Barnes P J
Elevation of exhaled ethane concentration in asthma.
American journal of respiratory and critical care medicine 2000;162(4 Pt 1):1450-4.
-
2000: Lim S; Roche N; Oliver B G; Mattos W; Barnes P J; Chung K F
Balance of matrix metalloprotease-9 and tissue inhibitor of metalloprotease-1 from alveolar macrophages in cigarette smokers. Regulation by interleukin-10.
American journal of respiratory and critical care medicine 2000;162(4 Pt 1):1355-60.
-
2000: Hanazawa T; Kharitonov S A; Barnes P J
Increased nitrotyrosine in exhaled breath condensate of patients with asthma.
American journal of respiratory and critical care medicine 2000;162(4 Pt 1):1273-6.
-
2000: Lim S; Jatakanon A; Gordon D; Macdonald C; Chung K F; Barnes P J
Comparison of high dose inhaled steroids, low dose inhaled steroids plus low dose theophylline, and low dose inhaled steroids alone in chronic asthma in general practice.
Thorax 2000;55(10):837-41.
-
2000: Montuschi P; Collins J V; Ciabattoni G; Lazzeri N; Corradi M; Kharitonov S A; Barnes P J
Exhaled 8-isoprostane as an in vivo biomarker of lung oxidative stress in patients with COPD and healthy smokers.
American journal of respiratory and critical care medicine 2000;162(3 Pt 1):1175-7.
-
2000: Ito K; Barnes P J; Adcock I M
Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12.
Molecular and cellular biology 2000;20(18):6891-903.
-
2000: Paredi P; Kharitonov S A; Leak D; Ward S; Cramer D; Barnes P J
Exhaled ethane, a marker of lipid peroxidation, is elevated in chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2000;162(2 Pt 1):369-73.
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2000: Spicuzza L; Haddad E B; Birrell M; Ling A; Clarke D; Venkatesan P; Barnes P J; Belvisi M G
Characterization of the effects of cannabinoids on guinea-pig tracheal smooth muscle tone: role in the modulation of acetylcholine release from parasympathetic nerves.
British journal of pharmacology 2000;130(7):1720-6.
-
2000: Barnes P J
Chronic obstructive pulmonary disease.
The New England journal of medicine 2000;343(4):269-80.
-
2000: Newton R; Cambridge L; Hart L A; Stevens D A; Lindsay M A; Barnes P J
The MAP kinase inhibitors, PD098059, UO126 and SB203580, inhibit IL-1beta-dependent PGE(2) release via mechanistically distinct processes.
British journal of pharmacology 2000;130(6):1353-61.
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2000: Nightingale J A; Maggs R; Cullinan P; Donnelly L E; Rogers D F; Kinnersley R; Chung K F; Barnes P J; Ashmore M; Newman-Taylor A
Airway inflammation after controlled exposure to diesel exhaust particulates.
American journal of respiratory and critical care medicine 2000;162(1):161-6.
-
2000: Staples K J; Bergmann M; Barnes P J; Newton R
Stimulus-specific inhibition of IL-5 by cAMP-elevating agents and IL-10 reveals differential mechanisms of action.
Biochemical and biophysical research communications 2000;273(3):811-5.
-
2000: Katsunuma T; Fujita K; Mak J C; Barnes P J; Ueno K; Iikura Y
Beta-adrenergic agonists and bronchial hyperreactivity: role of beta2-adrenergic and tachykinin neurokinin-2 receptors.
The Journal of allergy and clinical immunology 2000;106(1 Pt 2):S104-8.
-
2000: Kankaanranta H; Lindsay M A; Giembycz M A; Zhang X; Moilanen E; Barnes P J
Delayed eosinophil apoptosis in asthma.
The Journal of allergy and clinical immunology 2000;106(1 Pt 1):77-83.
-
2000: Barnes P J
New directions in allergic diseases: mechanism-based anti-inflammatory therapies.
The Journal of allergy and clinical immunology 2000;106(1 Pt 1):5-16.
-
2000: Finney P A; Belvisi M G; Donnelly L E; Chuang T T; Mak J C; Scorer C; Barnes P J; Adcock I M; Giembycz M A
Albuterol-induced downregulation of Gsalpha accounts for pulmonary beta(2)-adrenoceptor desensitization in vivo.
The Journal of clinical investigation 2000;106(1):125-35.
-
2000: Ranu H K; Mak J C; Barnes P J; Harding S E
G(i)-dependent suppression of beta(1)-adrenoceptor effects in ventricular myocytes from NE-treated guinea pigs.
American journal of physiology. Heart and circulatory physiology 2000;278(6):H1807-14.
-
2000: Lynch O T; Giembycz M A; Daniels I; Barnes P J; Lindsay M A
Pleiotropic role of lyn kinase in leukotriene B(4)-induced eosinophil activation.
Blood 2000;95(11):3541-7.
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2000: Haddad E B; Fox A J; Rousell J; Burgess G; McIntyre P; Barnes P J; Chung K F
Post-transcriptional regulation of bradykinin B1 and B2 receptor gene expression in human lung fibroblasts by tumor necrosis factor-alpha: modulation by dexamethasone.
Molecular pharmacology 2000;57(6):1123-31.
-
2000: Leckie M J; Bryan S A; Khan J; Dewar A; Aikman S L; McGrath J; Okrongly D A; Burman J F; Barnes P J; Hansel T T
Automated quantitation of circulating neutrophil and eosinophil activation in asthmatic patients.
Thorax 2000;55(6):471-7.
-
2000: Lim S; John M; Seybold J; Taylor D; Witt C; Barnes P J; Chung K F
Increased interleukin-10 and macrophage inflammatory protein-1 alpha release from blood monocytes ex vivo during late-phase response to allergen in asthma.
Allergy 2000;55(5):489-95.
-
2000: Mak J C; Roffel A F; Katsunuma T; Elzinga C R; Zaagsma J; Barnes P J
Up-regulation of airway smooth muscle histamine H(1) receptor mRNA, protein, and function by beta(2)-adrenoceptor activation.
Molecular pharmacology 2000;57(5):857-64.
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2000: Paredi P; Kharitonov S A; Leak D; Shah P L; Cramer D; Hodson M E; Barnes P J
Exhaled ethane is elevated in cystic fibrosis and correlates with carbon monoxide levels and airway obstruction.
American journal of respiratory and critical care medicine 2000;161(4 Pt 1):1247-51.
-
2000: Barnes P J
Endogenous inhibitory mechanisms in asthma.
American journal of respiratory and critical care medicine 2000;161(3 Pt 2):S176-81.
-
2000: Lim S; Jatakanon A; Meah S; Oates T; Chung K F; Barnes P J
Relationship between exhaled nitric oxide and mucosal eosinophilic inflammation in mild to moderately severe asthma.
Thorax 2000;55(3):184-8.
-
2000: Barnes P J
The pharmacological properties of tiotropium.
Chest 2000;117(2 Suppl):63S-6S.
-
2000: Barnes P J
Mechanisms in COPD: differences from asthma.
Chest 2000;117(2 Suppl):10S-4S.
-
2000: Nightingale J A; Rogers D F; Chung K F; Barnes P J
No effect of inhaled budesonide on the response to inhaled ozone in normal subjects.
American journal of respiratory and critical care medicine 2000;161(2 Pt 1):479-86.
-
2000: Antuni J D; Kharitonov S A; Hughes D; Hodson M E; Barnes P J
Increase in exhaled carbon monoxide during exacerbations of cystic fibrosis.
Thorax 2000;55(2):138-42.
-
2000: Bryan S A; Leckie M J; Hansel T T; Barnes P J
Novel therapy for asthma.
Expert opinion on investigational drugs 2000;9(1):25-42.
-
2000: Leckie M J; Bryan S A; Hansel T T; Barnes P J
Novel therapy for COPD.
Expert opinion on investigational drugs 2000;9(1):3-23.
-
2000: Hanazawa T; Antuni J D; Kharitonov S A; Barnes P J
Intranasal administration of eotaxin increases nasal eosinophils and nitric oxide in patients with allergic rhinitis.
The Journal of allergy and clinical immunology 2000;105(1 Pt 1):58-64.
-
2000: Hart L; Lim S; Adcock I; Barnes P J; Chung K F
Effects of inhaled corticosteroid therapy on expression and DNA-binding activity of nuclear factor kappaB in asthma.
American journal of respiratory and critical care medicine 2000;161(1):224-31.
-
2000: Jatakanon A; Lim S; Barnes P J
Changes in sputum eosinophils predict loss of asthma control.
American journal of respiratory and critical care medicine 2000;161(1):64-72.
-
1999: Nightingale J A; Rogers D F; Barnes P J
Effect of inhaled ozone on exhaled nitric oxide, pulmonary function, and induced sputum in normal and asthmatic subjects.
Thorax 1999;54(12):1061-9.
-
1999: Juniper E F; Svensson K; O'Byrne P M; Barnes P J; Bauer C A; Löfdahl C G; Postma D S; Pauwels R A; Tattersfield A E; Ullman A
Asthma quality of life during 1 year of treatment with budesonide with or without formoterol.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;14(5):1038-43.
-
1999: Kharitonov S A; Sapienza M M; Chung K F; Barnes P J
Prostaglandins mediate bradykinin-induced reduction of exhaled nitric oxide in asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;14(5):1023-7.
-
1999: Barnes P J
Therapeutic strategies for allergic diseases.
Nature 1999;402(6760 Suppl):B31-8.
-
1999: Lynch O T; Giembycz M A; Barnes P J; Hellewell P G; Lindsay M A
'Outside-in' signalling mechanisms underlying CD11b/CD18-mediated NADPH oxidase activation in human adherent blood eosinophils.
British journal of pharmacology 1999;128(6):1149-58.
-
1999: Barnes P J
Novel approaches and targets for treatment of chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 1999;160(5 Pt 2):S72-9.
-
1999: Culpitt S V; Maziak W; Loukidis S; Nightingale J A; Matthews J L; Barnes P J
Effect of high dose inhaled steroid on cells, cytokines, and proteases in induced sputum in chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 1999;160(5 Pt 1):1635-9.
-
1999: Jatakanon A; Uasuf C; Maziak W; Lim S; Chung K F; Barnes P J
Neutrophilic inflammation in severe persistent asthma.
American journal of respiratory and critical care medicine 1999;160(5 Pt 1):1532-9.
-
1999: Uasuf C G; Jatakanon A; James A; Kharitonov S A; Wilson N M; Barnes P J
Exhaled carbon monoxide in childhood asthma.
The Journal of pediatrics 1999;135(5):569-74.
-
1999: Paredi P; Biernacki W; Invernizzi G; Kharitonov S A; Barnes P J
Exhaled carbon monoxide levels elevated in diabetes and correlated with glucose concentration in blood: a new test for monitoring the disease?
Chest 1999;116(4):1007-11.
-
1999: Paredi P; Shah P L; Montuschi P; Sullivan P; Hodson M E; Kharitonov S A; Barnes P J
Increased carbon monoxide in exhaled air of patients with cystic fibrosis.
Thorax 1999;54(10):917-20.
-
1999: Salmon M; Walsh D A; Koto H; Barnes P J; Chung K F
Repeated allergen exposure of sensitized Brown-Norway rats induces airway cell DNA synthesis and remodelling.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;14(3):633-41.
-
1999: Rogers D F; Barnes P J
COPD: new developments and therapeutic opportunities.
Trends in pharmacological sciences 1999;20(9):352-4.
-
1999: Bernareggi M M; Belvisi M G; Patel H; Barnes P J; Giembycz M A
Anti-spasmogenic activity of isoenzyme-selective phosphodiesterase inhibitors in guinea-pig trachealis.
British journal of pharmacology 1999;128(2):327-36.
-
1999: Katsunuma T; Roffel A F; Elzinga C R; Zaagsma J; Barnes P J; Mak J C
beta(2)-adrenoceptor agonist-induced upregulation of tachykinin NK(2) receptor expression and function in airway smooth muscle.
American journal of respiratory cell and molecular biology 1999;21(3):409-17.
-
1999: Chung K F; Barnes P J
Cytokines in asthma.
Thorax 1999;54(9):825-57.
-
1999: Barnes P J
Effect of beta-agonists on inflammatory cells.
The Journal of allergy and clinical immunology 1999;104(2 Pt 2):S10-7.
-
1999: Evans D J; Lindsay M A; Webb B L; Kankaanranta H; Giembycz M A; O'Connor B J; Barnes P J
Expression and activation of protein kinase C-zeta in eosinophils after allergen challenge.
The American journal of physiology 1999;277(2 Pt 1):L233-9.
-
1999: Tattersfield A E; Postma D S; Barnes P J; Svensson K; Bauer C A; O'Byrne P M; Löfdahl C G; Pauwels R A; Ullman A
Exacerbations of asthma: a descriptive study of 425 severe exacerbations. The FACET International Study Group.
American journal of respiratory and critical care medicine 1999;160(2):594-9.
-
1999: Kankaanranta H; De Souza P M; Barnes P J; Salmon M; Giembycz M A; Lindsay M A
SB 203580, an inhibitor of p38 mitogen-activated protein kinase, enhances constitutive apoptosis of cytokine-deprived human eosinophils.
The Journal of pharmacology and experimental therapeutics 1999;290(2):621-8.
-
1999: Salmon M; Walsh D A; Huang T J; Barnes P J; Leonard T B; Hay D W; Chung K F
Involvement of cysteinyl leukotrienes in airway smooth muscle cell DNA synthesis after repeated allergen exposure in sensitized Brown Norway rats.
British journal of pharmacology 1999;127(5):1151-8.
-
1999: Hisada T; Adcock I M; Nasuhara Y; Salmon M; Huang T J; Barnes P J; Chung K F
Inhibition of ozone-induced lung neutrophilia and nuclear factor-kappaB binding activity by vitamin A in rat.
European journal of pharmacology 1999;377(1):63-8.
-
1999: Nasuhara Y; Adcock I M; Catley M; Barnes P J; Newton R
Differential IkappaB kinase activation and IkappaBalpha degradation by interleukin-1beta and tumor necrosis factor-alpha in human U937 monocytic cells. Evidence for additional regulatory steps in kappaB-dependent transcription.
The Journal of biological chemistry 1999;274(28):19965-72.
-
1999: Taylor D A; Jensen M W; Kanabar V; Engelstätter R; Steinijans V W; Barnes P J; O'Connor B J
A dose-dependent effect of the novel inhaled corticosteroid ciclesonide on airway responsiveness to adenosine-5'-monophosphate in asthmatic patients.
American journal of respiratory and critical care medicine 1999;160(1):237-43.
-
1999: Montuschi P; Corradi M; Ciabattoni G; Nightingale J; Kharitonov S A; Barnes P J
Increased 8-isoprostane, a marker of oxidative stress, in exhaled condensate of asthma patients.
American journal of respiratory and critical care medicine 1999;160(1):216-20.
-
1999: Adcock I M; Nasuhara Y; Stevens D A; Barnes P J
Ligand-induced differentiation of glucocorticoid receptor (GR) trans-repression and transactivation: preferential targetting of NF-kappaB and lack of I-kappaB involvement.
British journal of pharmacology 1999;127(4):1003-11.
-
1999: Patel H J; Venkatesan P; Halfpenny J; Yacoub M H; Fox A; Barnes P J; Belvisi M G
Modulation of acetylcholine release from parasympathetic nerves innervating guinea-pig and human trachea by endomorphin-1 and -2.
European journal of pharmacology 1999;374(1):21-4.
-
1999: Thomas P S; Yates D H; Barnes P J
Sputum induction as a method of analyzing pulmonary cells: reproducibility and acceptability.
The Journal of asthma : official journal of the Association for the Care of Asthma 1999;36(4):335-41.
-
1999: Nightingale J A; Rogers D F; Barnes P J
Differential effect of formoterol on adenosine monophosphate and histamine reactivity in asthma.
American journal of respiratory and critical care medicine 1999;159(6):1786-90.
-
1999: Haddad E B; Patel H; Keeling J E; Yacoub M H; Barnes P J; Belvisi M G
Pharmacological characterization of the muscarinic receptor antagonist, glycopyrrolate, in human and guinea-pig airways.
British journal of pharmacology 1999;127(2):413-20.
-
1999: Paredi P; Kharitonov S A; Loukides S; Pantelidis P; du Bois R M; Barnes P J
Exhaled nitric oxide is increased in active fibrosing alveolitis.
Chest 1999;115(5):1352-6.
-
1999: Thomas P S; Geddes D M; Barnes P J
Pseudo-steroid resistant asthma.
Thorax 1999;54(4):352-6.
-
1999: Barnes P J
Genetics and pulmonary medicine. 9. Molecular genetics of chronic obstructive pulmonary disease.
Thorax 1999;54(3):245-52.
-
1999: Jatakanon A; Lalloo U G; Lim S; Chung K F; Barnes P J
Increased neutrophils and cytokines, TNF-alpha and IL-8, in induced sputum of non-asthmatic patients with chronic dry cough.
Thorax 1999;54(3):234-7.
-
1999: Saunders M A; Belvisi M G; Cirino G; Barnes P J; Warner T D; Mitchell J A
Mechanisms of prostaglandin E2 release by intact cells expressing cyclooxygenase-2: evidence for a 'two-component' model.
The Journal of pharmacology and experimental therapeutics 1999;288(3):1101-6.
-
1999: Jatakanon A; Kharitonov S; Lim S; Barnes P J
Effect of differing doses of inhaled budesonide on markers of airway inflammation in patients with mild asthma.
Thorax 1999;54(2):108-14.
-
1999: Paredi P; Leckie M J; Horvath I; Allegra L; Kharitonov S A; Barnes P J
Changes in exhaled carbon monoxide and nitric oxide levels following allergen challenge in patients with asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;13(1):48-52.
-
1999: Hall S E; Lim S; Witherden I R; Tetley T D; Barnes P J; Kamal A M; Smith S F
Lung type II cell and macrophage annexin I release: differential effects of two glucocorticoids.
The American journal of physiology 1999;276(1 Pt 1):L114-21.
-
1999: Lim S; Jatakanon A; John M; Gilbey T; O'connor B J; Chung K F; Barnes P J
Effect of inhaled budesonide on lung function and airway inflammation. Assessment by various inflammatory markers in mild asthma.
American journal of respiratory and critical care medicine 1999;159(1):22-30.
-
1999: Patel H J; Douglas G J; Herd C M; Spina D; Giembycz M A; Barnes P J; Belvisi M G; Page C P
Antigen-induced bronchial hyperresponsiveness in the rabbit is not dependent on M(2)-receptor dysfunction.
Pulmonary pharmacology & therapeutics 1999;12(4):245-55.
-
1999: Barnes P J
Strategies for novel COPD therapies.
Pulmonary pharmacology & therapeutics 1999;12(2):67-71.
-
1998: Stirling R G; Kharitonov S A; Campbell D; Robinson D S; Durham S R; Chung K F; Barnes P J
Increase in exhaled nitric oxide levels in patients with difficult asthma and correlation with symptoms and disease severity despite treatment with oral and inhaled corticosteroids. Asthma and Allergy Group.
Thorax 1998;53(12):1030-4.
-
1998: Barnes P J; Chung K F; Page C P
Inflammatory mediators of asthma: an update.
Pharmacological reviews 1998;50(4):515-96.
-
1998: Dowling R B; Newton R; Robichaud A; Cole P J; Barnes P J; Wilson R
Effect of inhibition of nitric oxide synthase on Pseudomonas aeruginosa infection of respiratory mucosa in vitro.
American journal of respiratory cell and molecular biology 1998;19(6):950-8.
-
1998: Barnes P J; Woolcock A J
Difficult asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;12(5):1209-18.
-
1998: Jatakanon A; Lim S; Chung K F; Barnes P J
An inhaled steroid improves markers of airway inflammation in patients with mild asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;12(5):1084-8.
-
1998: Newton R; Seybold J; Kuitert L M; Bergmann M; Barnes P J
Repression of cyclooxygenase-2 and prostaglandin E2 release by dexamethasone occurs by transcriptional and post-transcriptional mechanisms involving loss of polyadenylated mRNA.
The Journal of biological chemistry 1998;273(48):32312-21.
-
1998: Barnes P J
Pharmacology of airway smooth muscle.
American journal of respiratory and critical care medicine 1998;158(5 Pt 3):S123-32.
-
1998: Hart L A; Krishnan V L; Adcock I M; Barnes P J; Chung K F
Activation and localization of transcription factor, nuclear factor-kappaB, in asthma.
American journal of respiratory and critical care medicine 1998;158(5 Pt 1):1585-92.
-
1998: Montuschi P; Ciabattoni G; Paredi P; Pantelidis P; du Bois R M; Kharitonov S A; Barnes P J
8-Isoprostane as a biomarker of oxidative stress in interstitial lung diseases.
American journal of respiratory and critical care medicine 1998;158(5 Pt 1):1524-7.
-
1998: Kharitonov S A; Sapienza M A; Barnes P J; Chung K F
Prostaglandins E2 and F2alpha reduce exhaled nitric oxide in normal and asthmatic subjects irrespective of airway caliber changes.
American journal of respiratory and critical care medicine 1998;158(5 Pt 1):1374-8.
-
1998: Horvath I; Loukides S; Wodehouse T; Kharitonov S A; Cole P J; Barnes P J
Increased levels of exhaled carbon monoxide in bronchiectasis: a new marker of oxidative stress.
Thorax 1998;53(10):867-70.
-
1998: Barnes P J
Chronic obstructive pulmonary disease: new opportunities for drug development.
Trends in pharmacological sciences 1998;19(10):415-23.
-
1998: Barnes P J
Efficacy of inhaled corticosteroids in asthma.
The Journal of allergy and clinical immunology 1998;102(4 Pt 1):531-8.
-
1998: Horváth I; Donnelly L E; Kiss A; Kharitonov S A; Lim S; Chung K F; Barnes P J
Combined use of exhaled hydrogen peroxide and nitric oxide in monitoring asthma.
American journal of respiratory and critical care medicine 1998;158(4):1042-6.
-
1998: Lindsay M A; Haddad E B; Rousell J; Teixeira M M; Hellewell P G; Barnes P J; Giembycz M A
Role of the mitogen-activated protein kinases and tyrosine kinases during leukotriene B4-induced eosinophil activation.
Journal of leukocyte biology 1998;64(4):555-62.
-
1998: Wright L C; Seybold J; Robichaud A; Adcock I M; Barnes P J
Phosphodiesterase expression in human epithelial cells.
The American journal of physiology 1998;275(4 Pt 1):L694-700.
-
1998: Paredi P; Loukides S; Ward S; Cramer D; Spicer M; Kharitonov S A; Barnes P J
Exhalation flow and pressure-controlled reservoir collection of exhaled nitric oxide for remote and delayed analysis.
Thorax 1998;53(9):775-9.
-
1998: Loukides S; Horvath I; Wodehouse T; Cole P J; Barnes P J
Elevated levels of expired breath hydrogen peroxide in bronchiectasis.
American journal of respiratory and critical care medicine 1998;158(3):991-4.
-
1998: Horváth I; Donnelly L E; Kiss A; Paredi P; Kharitonov S A; Barnes P J
Raised levels of exhaled carbon monoxide are associated with an increased expression of heme oxygenase-1 in airway macrophages in asthma: a new marker of oxidative stress.
Thorax 1998;53(8):668-72.
-
1998: Adcock I M; Nasuhari Y; Barnes P J
Role of CBP in glucocorticoid-induced gene repression.
Biochemical Society transactions 1998;26(3):S255.
-
1998: Loukides S; Kharitonov S; Wodehouse T; Cole P J; Barnes P J
Effect of arginine on mucociliary function in primary ciliary dyskinesia.
Lancet 1998;352(9125):371-2.
-
1998: Patel H J; Giembycz M A; Keeling J E; Barnes P J; Belvisi M G
Inhibition of cholinergic neurotransmission in guinea pig trachea by NS1619, a putative activator of large-conductance, calcium-activated potassium channels.
The Journal of pharmacology and experimental therapeutics 1998;286(2):952-8.
-
1998: Seybold J; Newton R; Wright L; Finney P A; Suttorp N; Barnes P J; Adcock I M; Giembycz M A
Induction of phosphodiesterases 3B, 4A4, 4D1, 4D2, and 4D3 in Jurkat T-cells and in human peripheral blood T-lymphocytes by 8-bromo-cAMP and Gs-coupled receptor agonists. Potential role in beta2-adrenoreceptor desensitization.
The Journal of biological chemistry 1998;273(32):20575-88.
-
1998: Nightingale J A; Rogers D F; Hart L A; Kharitonov S A; Chung K F; Barnes P J
Effect of inhaled endotoxin on induced sputum in normal, atopic, and atopic asthmatic subjects.
Thorax 1998;53(7):563-71.
-
1998: Barnes P J; Adcock I M
Transcription factors and asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;12(1):221-34.
-
1998: Taylor D A; McGrath J L; O'Connor B J; Barnes P J
Allergen-induced early and late asthmatic responses are not affected by inhibition of endogenous nitric oxide.
American journal of respiratory and critical care medicine 1998;158(1):99-106.
-
1998: Taylor D A; McGrath J L; Orr L M; Barnes P J; O'Connor B J
Effect of endogenous nitric oxide inhibition on airway responsiveness to histamine and adenosine-5'-monophosphate in asthma.
Thorax 1998;53(6):483-9.
-
1998: Newton R; Hart L A; Stevens D A; Bergmann M; Donnelly L E; Adcock I M; Barnes P J
Effect of dexamethasone on interleukin-1beta-(IL-1beta)-induced nuclear factor-kappaB (NF-kappaB) and kappaB-dependent transcription in epithelial cells.
European journal of biochemistry / FEBS 1998;254(1):81-9.
-
1998: Kelly J J; Barnes P J; Giembycz M A
Characterization of phosphodiesterase 4 in guinea-pig macrophages: multiple activities, association states and sensitivity to selective inhibitors.
British journal of pharmacology 1998;124(1):129-40.
-
1998: Lindsay M A; Perkins R S; Barnes P J; Giembycz M A
Leukotriene B4 activates the NADPH oxidase in eosinophils by a pertussis toxin-sensitive mechanism that is largely independent of arachidonic acid mobilization.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(9):4526-34.
-
1998: Chung K F; Barnes P J
Zafirlukast (Accolate).
Drugs of today (Barcelona, Spain : 1998) 1998;34(4):375-88.
-
1998: Barnes P J
Current issues for establishing inhaled corticosteroids as the antiinflammatory agents of choice in asthma.
The Journal of allergy and clinical immunology 1998;101(4 Pt 2):S427-33.
-
1998: Sapienza M A; Kharitonov S A; Horvath I; Chung K F; Barnes P J
Effect of inhaled L-arginine on exhaled nitric oxide in normal and asthmatic subjects.
Thorax 1998;53(3):172-5.
-
1998: Lalloo U G; Lim S; DuBois R; Barnes P J; Chung K F
Increased sensitivity of the cough reflex in progressive systemic sclerosis patients with interstitial lung disease.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;11(3):702-5.
-
1998: Spicuzza L; Giembycz M A; Barnes P J; Belvisi M G
Prostaglandin E2 suppression of acetylcholine release from parasympathetic nerves innervating guinea-pig trachea by interacting with prostanoid receptors of the EP3-subtype.
British journal of pharmacology 1998;123(6):1246-52.
-
1998: Barnes P J; Pedersen S; Busse W W
Efficacy and safety of inhaled corticosteroids. New developments.
American journal of respiratory and critical care medicine 1998;157(3 Pt 2):S1-53.
-
1998: Maziak W; Loukides S; Culpitt S; Sullivan P; Kharitonov S A; Barnes P J
Exhaled nitric oxide in chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 1998;157(3 Pt 1):998-1002.
-
1998: Salmon M; Koto H; Lynch O T; Haddad E B; Lamb N J; Quinlan G J; Barnes P J; Chung K F
Proliferation of airway epithelium after ozone exposure: effect of apocynin and dexamethasone.
American journal of respiratory and critical care medicine 1998;157(3 Pt 1):970-7.
-
1998: Seldon P M; Stevens D A; Adcock I M; O'Connor B J; Barnes P J; Giembycz M A
Albuterol does not antagonize the inhibitory effect of dexamethasone on monocyte cytokine release.
American journal of respiratory and critical care medicine 1998;157(3 Pt 1):803-9.
-
1998: Bergmann M; Hart L; Lindsay M; Barnes P J; Newton R
IkappaBalpha degradation and nuclear factor-kappaB DNA binding are insufficient for interleukin-1beta and tumor necrosis factor-alpha-induced kappaB-dependent transcription. Requirement for an additional activation pathway.
The Journal of biological chemistry 1998;273(12):6607-10.
-
1998: Barnes P J
New therapies for chronic obstructive pulmonary disease.
Thorax 1998;53(2):137-47.
-
1998: Yates D H; Worsdell M; Barnes P J
Effect of an inhaled glucocorticosteroid on mast cell and smooth muscle beta 2 adrenergic tolerance in mild asthma.
Thorax 1998;53(2):110-3.
-
1998: Jatakanon A; Lim S; Kharitonov S A; Chung K F; Barnes P J
Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma.
Thorax 1998;53(2):91-5.
-
1998: Nightingale J A; Rogers D F; Barnes P J
Effect of repeated sputum induction on cell counts in normal volunteers.
Thorax 1998;53(2):87-90.
-
1998: Katsunuma T; Mak J C; Barnes P J
Glucocorticoids reduce tachykinin NK2 receptor expression in bovine tracheal smooth muscle.
European journal of pharmacology 1998;344(1):99-106.
-
1998: John M; Au B T; Jose P J; Lim S; Saunders M; Barnes P J; Mitchell J A; Belvisi M G; Chung K F
Expression and release of interleukin-8 by human airway smooth muscle cells: inhibition by Th-2 cytokines and corticosteroids.
American journal of respiratory cell and molecular biology 1998;18(1):84-90.
-
1998: John M; Lim S; Seybold J; Jose P; Robichaud A; O'Connor B; Barnes P J; Chung K F
Inhaled corticosteroids increase interleukin-10 but reduce macrophage inflammatory protein-1alpha, granulocyte-macrophage colony-stimulating factor, and interferon-gamma release from alveolar macrophages in asthma.
American journal of respiratory and critical care medicine 1998;157(1):256-62.
-
1998: Seldon P M; Barnes P J; Giembycz M A
Interleukin-10 does not mediate the inhibitory effect of PDE-4 inhibitors and other cAMP-elevating drugs on lipopolysaccharide-induced tumors necrosis factor-alpha generation from human peripheral blood monocytes.
Cell biochemistry and biophysics 1998;29(1-2):179-201.
-
1997: Kharitonov S A; Cailes J B; Black C M; du Bois R M; Barnes P J
Decreased nitric oxide in the exhaled air of patients with systemic sclerosis with pulmonary hypertension.
Thorax 1997;52(12):1051-5.
-
1997: Rousell J; Haddad el-B; Lindsay M A; Barnes P J
Regulation of m2 muscarinic receptor gene expression by platelet-derived growth factor: involvement of extracellular signal-regulated protein kinases in the down-regulation process.
Molecular pharmacology 1997;52(6):966-73.
-
1997: Taylor D A; Jensen M W; Aikman S L; Harris J G; Barnes P J; O'Connor B J
Comparison of salmeterol and albuterol-induced bronchoprotection against adenosine monophosphate and histamine in mild asthma.
American journal of respiratory and critical care medicine 1997;156(6):1731-7.
-
1997: Bergmann M; Barnes P J
[Molecular biologic aspects of chronic inflammation reaction in bronchial asthma: incentive for new therapeutic concepts?]
Pneumologie (Stuttgart, Germany) 1997;51(11):1071-8.
-
1997: Newton R; Stevens D A; Hart L A; Lindsay M; Adcock I M; Barnes P J
Superinduction of COX-2 mRNA by cycloheximide and interleukin-1beta involves increased transcription and correlates with increased NF-kappaB and JNK activation.
FEBS letters 1997;418(1-2):135-8.
-
1997: Evans D J; Taylor D A; Zetterstrom O; Chung K F; O'Connor B J; Barnes P J
A comparison of low-dose inhaled budesonide plus theophylline and high-dose inhaled budesonide for moderate asthma.
The New England journal of medicine 1997;337(20):1412-8.
-
1997: Pauwels R A; Löfdahl C G; Postma D S; Tattersfield A E; O'Byrne P; Barnes P J; Ullman A
Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group.
The New England journal of medicine 1997;337(20):1405-11.
-
1997: Yates D H; Worsdell M; Barnes P J
Effect of regular salmeterol treatment on albuterol-induced bronchoprotection in mild asthma.
American journal of respiratory and critical care medicine 1997;156(3 Pt 1):988-91.
-
1997: Meja K K; Barnes P J; Giembycz M A
Characterization of the prostanoid receptor(s) on human blood monocytes at which prostaglandin E2 inhibits lipopolysaccharide-induced tumour necrosis factor-alpha generation.
British journal of pharmacology 1997;122(1):149-57.
-
1997: Stone R A; Barnes P J; Chung K F
Effect of 5-HT1A receptor agonist, 8-OH-DPAT, on cough responses in the conscious guinea pig.
European journal of pharmacology 1997;332(2):201-7.
-
1997: Newton R; Kuitert L M; Bergmann M; Adcock I M; Barnes P J
Evidence for involvement of NF-kappaB in the transcriptional control of COX-2 gene expression by IL-1beta.
Biochemical and biophysical research communications 1997;237(1):28-32.
-
1997: Liu S F; Haddad E B; Adcock I; Salmon M; Koto H; Gilbey T; Barnes P J; Chung K F
Inducible nitric oxide synthase after sensitization and allergen challenge of Brown Norway rat lung.
British journal of pharmacology 1997;121(7):1241-6.
-
1997: Webb B L; Lindsay M A; Seybold J; Brand N J; Yacoub M H; Haddad E B; Barnes P J; Adcock I M; Giembycz M A
Identification of the protein kinase C isoenzymes in human lung and airways smooth muscle at the protein and mRNA level.
Biochemical pharmacology 1997;54(1):199-205.
-
1997: Evans D J; Barnes P J; Cluzel M; O'Connor B J
Effects of a potent platelet-activating factor antagonist, SR27417A, on allergen-induced asthmatic responses.
American journal of respiratory and critical care medicine 1997;156(1):11-6.
-
1997: Kharitonov S; Alving K; Barnes P J
Exhaled and nasal nitric oxide measurements: recommendations. The European Respiratory Society Task Force.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1997;10(7):1683-93.
-
1997: Yates D H; Kharitonov S A; Barnes P J
Effect of short- and long-acting inhaled beta2-agonists on exhaled nitric oxide in asthmatic patients.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1997;10(7):1483-8.
-
1997: Kharitonov S A; Barnes P J
Nasal contribution to exhaled nitric oxide during exhalation against resistance or during breath holding.
Thorax 1997;52(6):540-4.
-
1997: Mitchell J A; Saunders M; Barnes P J; Newton R; Belvisi M G
Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor kappaB) activation: role of arachidonic acid.
Molecular pharmacology 1997;51(6):907-12.
-
1997: Adcock I M; Newton R; Barnes P J
NF-kappa B involvement in IL-1 beta-induction of GM-CSF and COX-2: inhibition by glucocorticoids does not require I-kappa B.
Biochemical Society transactions 1997;25(2):154S.
-
1997: Newton R; Seybold J; Liu S F; Barnes P J
Alternate COX-2 transcripts are differentially regulated: implications for post-transcriptional control.
Biochemical and biophysical research communications 1997;234(1):85-9.
-
1997: Webb B L; Lindsay M A; Barnes P J; Giembycz M A
Protein kinase C isoenzymes in airway smooth muscle.
The Biochemical journal 1997;324 ( Pt 1)():167-75.
-
1997: Keatings V M; O'Connor B J; Wright L G; Huston D P; Corrigan C J; Barnes P J
Late response to allergen is associated with increased concentrations of tumor necrosis factor-alpha and IL-5 in induced sputum.
The Journal of allergy and clinical immunology 1997;99(5):693-8.
-
1997: Keatings V M; Evans D J; O'Connor B J; Barnes P J
Cellular profiles in asthmatic airways: a comparison of induced sputum, bronchial washings, and bronchoalveolar lavage fluid.
Thorax 1997;52(4):372-4.
-
1997: Takahashi T; Barnes P J; Kawikova I; Yacoub M H; Warner T D; Belvisi M G
Contraction of human airway smooth muscle by endothelin-1 and IRL 1620: effect of bosentan.
European journal of pharmacology 1997;324(2-3):219-22.
-
1997: Barnes P J; Karin M
Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases.
The New England journal of medicine 1997;336(15):1066-71.
-
1997: Belvisi M G; Saunders M A; Haddad el-B; Hirst S J; Yacoub M H; Barnes P J; Mitchell J A
Induction of cyclo-oxygenase-2 by cytokines in human cultured airway smooth muscle cells: novel inflammatory role of this cell type.
British journal of pharmacology 1997;120(5):910-6.
-
1997: Patel H J; Giembycz M A; Spicuzza L; Barnes P J; Belvisi M G
Naloxone-insensitive inhibition of acetylcholine release from parasympathetic nerves innervating guinea-pig trachea by the novel opioid, nociceptin.
British journal of pharmacology 1997;120(5):735-6.
-
1997: Bernareggi M; Mitchell J A; Barnes P J; Belvisi M G
Dual action of nitric oxide on airway plasma leakage.
American journal of respiratory and critical care medicine 1997;155(3):869-74.
-
1997: Barnes P J; Adcock I M
NF-kappa B: a pivotal role in asthma and a new target for therapy.
Trends in pharmacological sciences 1997;18(2):46-50.
-
1997: Saunders M A; Mitchell J A; Seldon P M; Yacoub M H; Barnes P J; Giembycz M A; Belvisi M G
Release of granulocyte-macrophage colony stimulating factor by human cultured airway smooth muscle cells: suppression by dexamethasone.
British journal of pharmacology 1997;120(4):545-6.
-
1997: Barnes P J
Current therapies for asthma. Promise and limitations.
Chest 1997;111(2 Suppl):17S-26S.
-
1997: Keatings V M; Jatakanon A; Worsdell Y M; Barnes P J
Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD.
American journal of respiratory and critical care medicine 1997;155(2):542-8.
-
1997: Keatings V M; Barnes P J
Granulocyte activation markers in induced sputum: comparison between chronic obstructive pulmonary disease, asthma, and normal subjects.
American journal of respiratory and critical care medicine 1997;155(2):449-53.
-
1997: John M; Hirst S J; Jose P J; Robichaud A; Berkman N; Witt C; Twort C H; Barnes P J; Chung K F
Human airway smooth muscle cells express and release RANTES in response to T helper 1 cytokines: regulation by T helper 2 cytokines and corticosteroids.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(4):1841-7.
-
1997: Fox A J; Barnes P J; Venkatesan P; Belvisi M G
Activation of large conductance potassium channels inhibits the afferent and efferent function of airway sensory nerves in the guinea pig.
The Journal of clinical investigation 1997;99(3):513-9.
-
1997: Kharitonov S A; Rajakulasingam K; O'Connor B; Durham S R; Barnes P J
Nasal nitric oxide is increased in patients with asthma and allergic rhinitis and may be modulated by nasal glucocorticoids.
The Journal of allergy and clinical immunology 1997;99(1 Pt 1):58-64.
-
1997: Barnes P J
Neural mechanisms in asthma: new developments.
Pediatric pulmonology. Supplement 1997;16():82-3.
-
1997: Barnes P J
Molecular mechanisms of glucocorticoid action in asthma.
Pulmonary pharmacology & therapeutics 1997;10(1):3-19.
-
1997: Mak J C; Barnes P J
In situ hybridization.
Methods in molecular biology (Clifton, N.J.) 1997;83():81-9.
-
1997: Barnes P J; Haddad E B; Rousell J
Regulation of muscarinic M2 receptors.
Life sciences 1997;60(13-14):1015-21.
-
1997: Newton R; Kuitert L M; Slater D M; Adcock I M; Barnes P J
Cytokine induction of cytosolic phospholipase A2 and cyclooxygenase-2 mRNA is suppressed by glucocorticoids in human epithelial cells.
Life sciences 1997;60(1):67-78.
-
1996: Kharitonov S A; Barnes P J
Nitric oxide in exhaled air is a new marker of airway inflammation.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo 1996;51(6):533-7.
-
1996: Nishikawa M; Mak J C; Barnes P J
Effect of short- and long-acting beta 2-adrenoceptor agonists on pulmonary beta 2-adrenoceptor expression in human lung.
European journal of pharmacology 1996;318(1):123-9.
-
1996: Kuitert L M; Newton R; Barnes N C; Adcock I M; Barnes P J
Eicosanoid mediator expression in mononuclear and polymorphonuclear cells in normal subjects and patients with atopic asthma and cystic fibrosis.
Thorax 1996;51(12):1223-8.
-
1996: Evans D J; Barnes P J; Spaethe S M; van Alstyne E L; Mitchell M I; O'Connor B J
Effect of a leukotriene B4 receptor antagonist, LY293111, on allergen induced responses in asthma.
Thorax 1996;51(12):1178-84.
-
1996: Berkman N; Krishnan V L; Gilbey T; Newton R; O'Connor B; Barnes P J; Chung K F
Expression of RANTES mRNA and protein in airways of patients with mild asthma.
American journal of respiratory and critical care medicine 1996;154(6 Pt 1):1804-11.
-
1996: Yates D H; Kharitonov S A; Barnes P J
An inhaled glucocorticoid does not prevent tolerance to the bronchoprotective effect of a long-acting inhaled beta 2-agonist.
American journal of respiratory and critical care medicine 1996;154(6 Pt 1):1603-7.
-
1996: Haddad E B; Rousell J; Lindsay M A; Barnes P J
Synergy between tumor necrosis factor alpha and interleukin 1beta in inducing transcriptional down-regulation of muscarinic M2 receptor gene expression. Involvement of protein kinase A and ceramide pathways.
The Journal of biological chemistry 1996;271(51):32586-92.
-
1996: Berkman N; Robichaud A; Robbins R A; Roesems G; Haddad E B; Barnes P J; Chung K F
Inhibition of inducible nitric oxide synthase expression by interleukin-4 and interleukin-13 in human lung epithelial cells.
Immunology 1996;89(3):363-7.
-
1996: Lalloo U G; Barnes P J; Chung K F
Pathophysiology and clinical presentations of cough.
The Journal of allergy and clinical immunology 1996;98(5 Pt 2):S91-6; discussion S96-7.
-
1996: Barnes P J
Neuroeffector mechanisms: the interface between inflammation and neuronal responses.
The Journal of allergy and clinical immunology 1996;98(5 Pt 2):S73-81; discussion S81-3.
-
1996: Koto H; Mak J C; Haddad E B; Xu W B; Salmon M; Barnes P J; Chung K F
Mechanisms of impaired beta-adrenoceptor-induced airway relaxation by interleukin-1beta in vivo in the rat.
The Journal of clinical investigation 1996;98(8):1780-7.
-
1996: Berkman N; John M; Roesems G; Jose P; Barnes P J; Chung K F
Interleukin 13 inhibits macrophage inflammatory protein-1 alpha production from human alveolar macrophages and monocytes.
American journal of respiratory cell and molecular biology 1996;15(3):382-9.
-
1996: Adcock I M; Gilbey T; Gelder C M; Chung K F; Barnes P J
Glucocorticoid receptor localization in normal and asthmatic lung.
American journal of respiratory and critical care medicine 1996;154(3 Pt 1):771-82.
-
1996: Kelly J J; Barnes P J; Giembycz M A
Phosphodiesterase 4 in macrophages: relationship between cAMP accumulation, suppression of cAMP hydrolysis and inhibition of [3H]R-(-)-rolipram binding by selective inhibitors.
The Biochemical journal 1996;318 ( Pt 2)():425-36.
-
1996: Barnes P J
Immunomodulation as asthma therapy: where do we stand?
The European respiratory journal. Supplement 1996;22():154s-159s.
-
1996: Giembycz M A; Corrigan C J; Seybold J; Newton R; Barnes P J
Identification of cyclic AMP phosphodiesterases 3, 4 and 7 in human CD4+ and CD8+ T-lymphocytes: role in regulating proliferation and the biosynthesis of interleukin-2.
British journal of pharmacology 1996;118(8):1945-58.
-
1996: Barnes P J
Inhaled glucocorticoids: new developments relevant to updating of the asthma management guidelines.
Respiratory medicine 1996;90(7):379-84.
-
1996: Barnes P J
Mechanisms of action of glucocorticoids in asthma.
American journal of respiratory and critical care medicine 1996;154(2 Pt 2):S21-6; discussion S26-7.
-
1996: Adcock I M; Brown C R; Barnes P J
Tumour necrosis factor alpha causes retention of activated glucocorticoid receptor within the cytoplasm of A549 cells.
Biochemical and biophysical research communications 1996;225(2):545-50.
-
1996: Barnes P J
New drugs for asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1996;26(7):738-45.
-
1996: Barnes P J
Pathophysiology of asthma.
British journal of clinical pharmacology 1996;42(1):3-10.
-
1996: Yates D H; Kharitonov S A; Thomas P S; Barnes P J
Endogenous nitric oxide is decreased in asthmatic patients by an inhibitor of inducible nitric oxide synthase.
American journal of respiratory and critical care medicine 1996;154(1):247-50.
-
1996: Liu S F; Adcock I M; Old R W; Barnes P J; Evans T W
Differential regulation of the constitutive and inducible nitric oxide synthase mRNA by lipopolysaccharide treatment in vivo in the rat.
Critical care medicine 1996;24(7):1219-25.
-
1996: Fox A J; Lalloo U G; Belvisi M G; Bernareggi M; Chung K F; Barnes P J
Bradykinin-evoked sensitization of airway sensory nerves: a mechanism for ACE-inhibitor cough.
Nature medicine 1996;2(7):814-7.
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1996: Yates D H; Kharitonov S A; Robbins R A; Thomas P S; Barnes P J
The effect of alcohol ingestion on exhaled nitric oxide.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1996;9(6):1130-3.
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1996: Ramnarine S I; Khawaja A M; Barnes P J; Rogers D F
Nitric oxide inhibition of basal and neurogenic mucus secretion in ferret trachea in vitro.
British journal of pharmacology 1996;118(4):998-1002.
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1996: Haddad E B; Mak J C; Belvisi M G; Nishikawa M; Rousell J; Barnes P J
Muscarinic and beta-adrenergic receptor expression in peripheral lung from normal and asthmatic patients.
The American journal of physiology 1996;270(6 Pt 1):L947-53.
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1996: Kharitonov S A; Chung K F; Evans D; O'Connor B J; Barnes P J
Increased exhaled nitric oxide in asthma is mainly derived from the lower respiratory tract.
American journal of respiratory and critical care medicine 1996;153(6 Pt 1):1773-80.
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1996: Gelder C M; Morrison J F; Chung K F; Barnes P J; Adcock I M
T cell receptor repertoire in peripheral blood and bronchial biopsies from normal and asthmatic subjects.
Biochemical Society transactions 1996;24(2):316S.
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1996: Gelder C M; Barnes P J; O'Connor B J; Chung K F; Adcock I M
Cytokine mRNA profiles of normal and asthmatic peripheral blood cells and endobronchial biopsies.
Biochemical Society transactions 1996;24(2):315S.
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1996: Adcock I M; Barnes P J
Ligand-induced differentiation of glucocorticoid receptor (GR) trans-repression and transactivation.
Biochemical Society transactions 1996;24(2):267S.
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1996: Haddad E B; Rousell J; Mak J C; Barnes P J
Transforming growth factor-beta 1 induces transcriptional down-regulation of m2 muscarinic receptor gene expression.
Molecular pharmacology 1996;49(5):781-7.
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1996: Mak J C; Nishikawa M; Haddad E B; Kwon O J; Hirst S J; Twort C H; Barnes P J
Localisation and expression of beta-adrenoceptor subtype mRNAs in human lung.
European journal of pharmacology 1996;302(1-3):215-21.
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1996: Liu S F; Newton R; Evans T W; Barnes P J
Differential regulation of cyclo-oxygenase-1 and cyclo-oxygenase-2 gene expression by lipopolysaccharide treatment in vivo in the rat.
Clinical science (London, England : 1979) 1996;90(4):301-6.
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1996: Belvisi M G; Patel H J; Takahashi T; Barnes P J; Giembycz M A
Paradoxical facilitation of acetylcholine release from parasympathetic nerves innervating guinea-pig trachea by isoprenaline.
British journal of pharmacology 1996;117(7):1413-20.
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1996: Evans D J; Lindsay M A; O'Connor B J; Barnes P J
Priming of circulating human eosinophils following late response to allergen challenge.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1996;9(4):703-8.
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1996: Berkman N; Robichaud A; Krishnan V L; Roesems G; Robbins R; Jose P J; Barnes P J; Chung K F
Expression of RANTES in human airway epithelial cells: effect of corticosteroids and interleukin-4, -10 and -13.
Immunology 1996;87(4):599-603.
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1996: Rousell J; Haddad E B; Mak J C; Webb B L; Giembycz M A; Barnes P J
Beta-Adrenoceptor-medicated down-regulation of M2 muscarinic receptors: role of cyclic adenosine 5'-monophosphate-dependent protein kinase and protein kinase C.
Molecular pharmacology 1996;49(4):629-35.
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1996: Sakamoto T; Barnes P J; Chung K F
Lack of a role for bradykinin in allergen-induced airway microvascular leakage and bronchoconstriction in the guinea pig.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1996;45(3):123-6.
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1996: Hirst S J; Barnes P J; Twort C H
PDGF isoform-induced proliferation and receptor expression in human cultured airway smooth muscle cells.
The American journal of physiology 1996;270(3 Pt 1):L415-28.
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1996: Lei Y H; Barnes P J; Rogers D F
Involvement of hydroxyl radicals in neurogenic airway plasma exudation and bronchoconstriction in guinea-pigs in vivo.
British journal of pharmacology 1996;117(3):449-454.
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1996: Kharitonov S A; Yates D H; Chung K F; Barnes P J
Changes in the dose of inhaled steroid affect exhaled nitric oxide levels in asthmatic patients.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1996;9(2):196-201.
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1996: Barnes P J
NO or no NO in asthma?
Thorax 1996;51(2):218-20.
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1996: Haddad E B; Salmon M; Koto H; Barnes P J; Adcock I; Chung K F
Ozone induction of cytokine-induced neutrophil chemoattractant (CINC) and nuclear factor-kappa b in rat lung: inhibition by corticosteroids.
FEBS letters 1996;379(3):265-8.
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1996: Kawikova I; Barnes P J; Takahashi T; Tadjkarimi S; Yacoub M H; Belvisi M G
8-Epi-PGF2 alpha, a novel noncyclooxygenase-derived prostaglandin, constricts airways in vitro.
American journal of respiratory and critical care medicine 1996;153(2):590-6.
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1996: Keatings V M; Collins P D; Scott D M; Barnes P J
Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma.
American journal of respiratory and critical care medicine 1996;153(2):530-4.
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1996: Adcock I M; Stevens D A; Barnes P J
Interactions of glucocorticoids and beta 2-agonists.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1996;9(1):160-8.
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1996: Hallsworth M P; Giembycz M A; Barnes P J; Lee T H
Cyclic AMP-elevating agents prolong or inhibit eosinophil survival depending on prior exposure to GM-CSF.
British journal of pharmacology 1996;117(1):79-86.
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1996: Kidney J C; Lotvall J O; Lei Y; Chung K F; Barnes P J
The effect of inhaled K+ channel openers on bronchoconstriction and airway microvascular leakage in anaesthetised guinea pigs.
European journal of pharmacology 1996;296(1):81-7.
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1996: Barnes P J
Molecular mechanisms of steroid action in asthma.
The Journal of allergy and clinical immunology 1996;97(1 Pt 2):159-68.
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1996: Newton R; Adcock I M; Barnes P J
Superinduction of NF-kappa B by actinomycin D and cycloheximide in epithelial cells.
Biochemical and biophysical research communications 1996;218(2):518-23.
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1996: Kharitonov S A; Yates D H; Barnes P J
Inhaled glucocorticoids decrease nitric oxide in exhaled air of asthmatic patients.
American journal of respiratory and critical care medicine 1996;153(1):454-7.
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1996: Barnes P J
Asthma therapy with aerosols: clinical relevance for the next decade.
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 1996;9(1):131-41.
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1996: Mak J C; Astolfi M; Zhang X L; Evangelista S; Manzini S; Barnes P J
Autoradiographic mapping of pulmonary NK1 and NK2 tachykinin receptors and changes after repeated antigen challenge in guinea pigs.
Peptides 1996;17(8):1389-95.
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1995: Cambrey A D; Kwon O J; Gray A J; Harrison N K; Yacoub M; Barnes P J; Laurent G J; Chung K F
Insulin-like growth factor I is a major fibroblast mitogen produced by primary cultures of human airway epithelial cells.
Clinical science (London, England : 1979) 1995;89(6):611-7.
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1995: Yates D H; O'Connor B J; Yilmaz G; Aikman S; Worsdell M; Barnes P J; Chung K F
Effect of acute and chronic inhaled furosemide on bronchial hyperresponsiveness in mild asthma.
American journal of respiratory and critical care medicine 1995;152(6 Pt 1):2173-5.
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1995: Adcock I M; Lane S J; Brown C R; Lee T H; Barnes P J
Abnormal glucocorticoid receptor-activator protein 1 interaction in steroid-resistant asthma.
The Journal of experimental medicine 1995;182(6):1951-8.
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1995: Barnes P J; Greening A P; Crompton G K
Glucocorticoid resistance in asthma.
American journal of respiratory and critical care medicine 1995;152(6 Pt 2):S125-40.
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1995: Barnes P J
Nitric oxide and asthma.
Research in immunology 1995;146(9):698-702.
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1995: Barnes P J
Anti-inflammatory mechanisms of glucocorticoids.
Biochemical Society transactions 1995;23(4):940-5.
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1995: Yates D H; Peters M J; Keatings V; Thomas P S; Barnes P J
Reduced dose salbutamol in comparison with standard dosage for symptom relief in asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1995;8(11):1847-51.
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1995: Barnes P J; Adcock I M
Transcription factors.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1995;25 Suppl 2():46-9.
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1995: Xu W B; Haddad E B; Tsukagoshi H; Adcock I; Barnes P J; Chung K F
Induction of macrophage inflammatory protein 2 gene expression by interleukin 1 beta in rat lung.
Thorax 1995;50(11):1136-40.
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1995: Berkman N; John M; Roesems G; Jose P J; Barnes P J; Chung K F
Inhibition of macrophage inflammatory protein-1 alpha expression by IL-10. Differential sensitivities in human blood monocytes and alveolar macrophages.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(9):4412-8.
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1995: Haddad E B; Liu S F; Salmon M; Robichaud A; Barnes P J; Chung K F
Expression of inducible nitric oxide synthase mRNA in Brown Norway rats exposed to ozone: effect of dexamethasone.
European journal of pharmacology 1995;293(3):287-90.
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1995: Haddad E B; Rousell J; Mak J C; Barnes P J
Long-term carbachol treatment-induced down-regulation of muscarinic M2-receptors but not m2 receptor mRNA in a human lung cell line.
British journal of pharmacology 1995;116(3):2027-32.
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1995: Lalloo U G; Fox A J; Belvisi M G; Chung K F; Barnes P J
Capsazepine inhibits cough induced by capsaicin and citric acid but not by hypertonic saline in guinea pigs.
Journal of applied physiology (Bethesda, Md. : 1985) 1995;79(4):1082-7.
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1995: Barnes P J
Molecular mechanisms of antiasthma therapy.
Annals of medicine 1995;27(5):531-5.
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1995: Yates D H; Sussman H S; Shaw M J; Barnes P J; Chung K F
Regular formoterol treatment in mild asthma. Effect on bronchial responsiveness during and after treatment.
American journal of respiratory and critical care medicine 1995;152(4 Pt 1):1170-4.
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1995: Gelder C M; Thomas P S; Yates D H; Adcock I M; Morrison J F; Barnes P J
Cytokine expression in normal, atopic, and asthmatic subjects using the combination of sputum induction and the polymerase chain reaction.
Thorax 1995;50(10):1033-7.
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1995: Berkman N; Jose P J; Williams T J; Schall T J; Barnes P J; Chung K F
Corticosteroid inhibition of macrophage inflammatory protein-1 alpha in human monocytes and alveolar macrophages.
The American journal of physiology 1995;269(4 Pt 1):L443-52.
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1995: Seldon P M; Barnes P J; Meja K; Giembycz M A
Suppression of lipopolysaccharide-induced tumor necrosis factor-alpha generation from human peripheral blood monocytes by inhibitors of phosphodiesterase 4: interaction with stimulants of adenylyl cyclase.
Molecular pharmacology 1995;48(4):747-57.
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1995: Baraniuk J N; Ohkubo K; Kwon O J; Mak J; Ali M; Davies R; Twort C; Kaliner M; Letarte M; Barnes P J
Localization of neutral endopeptidase (NEP) mRNA in human bronchi.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1995;8(9):1458-64.
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1995: Yates D H; Kharitonov S A; Robbins R A; Thomas P S; Barnes P J
Effect of a nitric oxide synthase inhibitor and a glucocorticosteroid on exhaled nitric oxide.
American journal of respiratory and critical care medicine 1995;152(3):892-6.
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1995: Patel H J; Barnes P J; Takahashi T; Tadjkarimi S; Yacoub M H; Belvisi M G
Evidence for prejunctional muscarinic autoreceptors in human and guinea pig trachea.
American journal of respiratory and critical care medicine 1995;152(3):872-8.
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1995: Barnes P J
Beta-adrenergic receptors and their regulation.
American journal of respiratory and critical care medicine 1995;152(3):838-60.
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1995: Perkins R S; Lindsay M A; Barnes P J; Giembycz M A
Early signalling events implicated in leukotriene B4-induced activation of the NADPH oxidase in eosinophils: role of Ca2+, protein kinase C and phospholipases C and D.
The Biochemical journal 1995;310 ( Pt 3)():795-806.
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1995: Barnes P J
Overview of neural mechanisms in asthma.
Pulmonary pharmacology 1995;8(4-5):151-9.
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1995: Haddad E B; Rousell J; Barnes P J
Muscarinic M2 receptor synthesis: study of receptor turnover with propylbenzilylcholine mustard.
European journal of pharmacology 1995;290(3):201-5.
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1995: Barnes P J; Holgate S T; Laitinen L A; Pauwels R
Asthma mechanisms, determinants of severity and treatment: the role of nedocromil sodium. Report of a workshop held in Whistler, British Columbia, Canada, 18-19 May 1995.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1995;25(8):771-87.
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1995: Haczku A; Chung K F; Sun J; Barnes P J; Kay A B; Moqbel R
Airway hyperresponsiveness, elevation of serum-specific IgE and activation of T cells following allergen exposure in sensitized Brown-Norway rats.
Immunology 1995;85(4):598-603.
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1995: Haczku A; Moqbel R; Jacobson M; Kay A B; Barnes P J; Chung K F
T-cells subsets and activation in bronchial mucosa of sensitized Brown-Norway rats after single allergen exposure.
Immunology 1995;85(4):591-7.
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1995: Kharitonov S A; Robbins R A; Yates D; Keatings V; Barnes P J
Acute and chronic effects of cigarette smoking on exhaled nitric oxide.
American journal of respiratory and critical care medicine 1995;152(2):609-12.
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1995: Ward J K; Barnes P J; Springall D R; Abelli L; Tadjkarimi S; Yacoub M H; Polak J M; Belvisi M G
Distribution of human i-NANC bronchodilator and nitric oxide-immunoreactive nerves.
American journal of respiratory cell and molecular biology 1995;13(2):175-84.
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1995: Mak J C; Nishikawa M; Shirasaki H; Miyayasu K; Barnes P J
Protective effects of a glucocorticoid on downregulation of pulmonary beta 2-adrenergic receptors in vivo.
The Journal of clinical investigation 1995;96(1):99-106.
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1995: Thomas P S; Yates D H; Barnes P J
Tumor necrosis factor-alpha increases airway responsiveness and sputum neutrophilia in normal human subjects.
American journal of respiratory and critical care medicine 1995;152(1):76-80.
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1995: Takahashi T; Ward J K; Tadjkarimi S; Yacoub M H; Barnes P J; Belvisi M G
5-Hydroxytryptamine facilitates cholinergic bronchoconstriction in human and guinea pig airways.
American journal of respiratory and critical care medicine 1995;152(1):377-80.
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1995: Tsukagoshi H; Haddad E B; Barnes P J; Chung K F
Bradykinin receptor subtypes in rat lung: effect of interleukin-1 beta.
The Journal of pharmacology and experimental therapeutics 1995;273(3):1257-63.
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1995: Kidney J; Dominguez M; Taylor P M; Rose M; Chung K F; Barnes P J
Immunomodulation by theophylline in asthma. Demonstration by withdrawal of therapy.
American journal of respiratory and critical care medicine 1995;151(6):1907-14.
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1995: Kharitonov S A; O'Connor B J; Evans D J; Barnes P J
Allergen-induced late asthmatic reactions are associated with elevation of exhaled nitric oxide.
American journal of respiratory and critical care medicine 1995;151(6):1894-9.
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1995: Kharitonov S A; Wells A U; O'Connor B J; Cole P J; Hansell D M; Logan-Sinclair R B; Barnes P J
Elevated levels of exhaled nitric oxide in bronchiectasis.
American journal of respiratory and critical care medicine 1995;151(6):1889-93.
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1995: Lei Y H; Barnes P J; Rogers D F
Mechanisms and modulation of airway plasma exudation after direct inhalation of cigarette smoke.
American journal of respiratory and critical care medicine 1995;151(6):1752-62.
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1995: Barnes P J
Nitric oxide and airway disease.
Annals of medicine 1995;27(3):389-93.
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1995: Kuitert L M; Angus R M; Barnes N C; Barnes P J; Bone M F; Chung K F; Fairfax A J; Higenbotham T W; O'Connor B J; Piotrowska B
Effect of a novel potent platelet-activating factor antagonist, modipafant, in clinical asthma.
American journal of respiratory and critical care medicine 1995;151(5):1331-5.
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1995: Adcock I M; Peters M J; Brown C R; Stevens D A; Barnes P J
High concentrations of beta-adrenergic agonists inhibit DNA binding of glucocorticoids in human lung in vitro.
Biochemical Society transactions 1995;23(2):217S.
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1995: Kwon O J; Jose P J; Robbins R A; Schall T J; Williams T J; Barnes P J
Glucocorticoid inhibition of RANTES expression in human lung epithelial cells.
American journal of respiratory cell and molecular biology 1995;12(5):488-96.
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1995: Adcock I M; Lane S J; Brown C R; Peters M J; Lee T H; Barnes P J
Differences in binding of glucocorticoid receptor to DNA in steroid-resistant asthma.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(7):3500-5.
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1995: Haddad E B; Salmon M; Sun J; Liu S; Das A; Adcock I; Barnes P J; Chung K F
Dexamethasone inhibits ozone-induced gene expression of macrophage inflammatory protein-2 in rat lung.
FEBS letters 1995;363(3):285-8.
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1995: Barnes P J; O'Connor B J
Use of a fixed combination beta 2-agonist and steroid dry powder inhaler in asthma.
American journal of respiratory and critical care medicine 1995;151(4):1053-7.
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1995: Peters M J; Adcock I M; Brown C R; Barnes P J
Beta-adrenoceptor agonists interfere with glucocorticoid receptor DNA binding in rat lung.
European journal of pharmacology 1995;289(2):275-81.
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1995: Barnes P J
Is asthma a nervous disease? The Parker B. Francis Lectureship.
Chest 1995;107(3 Suppl):119S-125S.
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1995: Barnes P J
Inhaled glucocorticoids for asthma.
The New England journal of medicine 1995;332(13):868-75.
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1995: Barnes P J
Cyclic nucleotides and phosphodiesterases and airway function.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1995;8(3):457-62.
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1995: Barnes P J; Liu S F
Regulation of pulmonary vascular tone.
Pharmacological reviews 1995;47(1):87-131.
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1995: Tsukagoshi H; Sun J; Kwon O; Barnes P J; Chung K F
Role of neutral endopeptidase in bronchial hyperresponsiveness to bradykinin induced by IL-1 beta.
Journal of applied physiology (Bethesda, Md. : 1985) 1995;78(3):921-7.
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1995: Tsukagoshi H; Haddad E B; Sun J; Barnes P J; Chung K F
Ozone-induced airway hyperresponsiveness: role of superoxide anions, NEP, and BK receptors.
Journal of applied physiology (Bethesda, Md. : 1985) 1995;78(3):1015-22.
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1995: Rousell J; Haddad E B; Mak J C; Barnes P J
Transcriptional down-regulation of m2 muscarinic receptor gene expression in human embryonic lung (HEL 299) cells by protein kinase C.
The Journal of biological chemistry 1995;270(13):7213-8.
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1995: Ward J K; Barnes P J; Tadjkarimi S; Yacoub M H; Belvisi M G
Evidence for the involvement of cGMP in neural bronchodilator responses in humal trachea.
The Journal of physiology 1995;483 ( Pt 2)():525-36.
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1995: Barnes P J; Liew F Y
Nitric oxide and asthmatic inflammation.
Immunology today 1995;16(3):128-30.
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1995: Kharitonov S A; Yates D; Springall D R; Buttery L; Polak J; Robbins R A; Barnes P J
Exhaled nitric oxide is increased in asthma.
Chest 1995;107(3 Suppl):156S-157S.
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1995: Hirst S J; Webb B L; Giembycz M A; Barnes P J; Twort C H
Inhibition of fetal calf serum-stimulated proliferation of rabbit cultured tracheal smooth muscle cells by selective inhibitors of protein kinase C and protein tyrosine kinase.
American journal of respiratory cell and molecular biology 1995;12(2):149-61.
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1995: Adcock I M; Brown C R; Gelder C M; Shirasaki H; Peters M J; Barnes P J
Effects of glucocorticoids on transcription factor activation in human peripheral blood mononuclear cells.
The American journal of physiology 1995;268(2 Pt 1):C331-8.
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1995: Kharitonov S A; Lubec G; Lubec B; Hjelm M; Barnes P J
L-arginine increases exhaled nitric oxide in normal human subjects.
Clinical science (London, England : 1979) 1995;88(2):135-9.
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1995: Elwood W; Sun J; Barnes P J; Giembycz M A; Chung K F
Inhibition of allergen-induced lung eosinophilia by type-III and combined type III- and IV-selective phosphodiesterase inhibitors in brown-Norway rats.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1995;44(2):83-6.
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1995: Kharitonov S A; Yates D; Barnes P J
Increased nitric oxide in exhaled air of normal human subjects with upper respiratory tract infections.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1995;8(2):295-7.
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1995: Harrison N K; Dawes K E; Kwon O J; Barnes P J; Laurent G J; Chung K F
Effects of neuropeptides on human lung fibroblast proliferation and chemotaxis.
The American journal of physiology 1995;268(2 Pt 1):L278-83.
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1995: Mak J C; Nishikawa M; Barnes P J
Glucocorticosteroids increase beta 2-adrenergic receptor transcription in human lung.
The American journal of physiology 1995;268(1 Pt 1):L41-6.
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1995: Fox A J; Barnes P J; Dray A
Stimulation of guinea-pig tracheal afferent fibres by non-isosmotic and low-chloride stimuli and the effect of frusemide.
The Journal of physiology 1995;482 ( Pt 1)():179-87.
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1995: Hayes J P; Kuo H P; Rohde J A; Newman Taylor A J; Barnes P J; Chung K F; Rogers D F
Neurogenic goblet cell secretion and bronchoconstriction in guinea pigs sensitised to trimellitic anhydride.
European journal of pharmacology 1995;292(2):127-34.
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1995: Belvisi M G; Ward J K; Mitchell J A; Barnes P J
Nitric oxide as a neurotransmitter in human airways.
Archives internationales de pharmacodynamie et de thérapie 1995;329(1):97-110.
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1995: Barnes P J; Belvisi M G; Mak J C; Haddad E B; O'Connor B
Tiotropium bromide (Ba 679 BR), a novel long-acting muscarinic antagonist for the treatment of obstructive airways disease.
Life sciences 1995;56(11-12):853-9.
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1995: Barnes P J
From pathophysiological mechanisms to pharmacological treatment of childhood asthma.
Pediatric pulmonology. Supplement 1995;11():40-1.
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1995: Zhang X L; Mak J C; Barnes P J
Characterization and autoradiographic mapping of [3H]CP96,345, a nonpeptide selective NK1 receptor antagonist in guinea pig lung.
Peptides 1995;16(5):867-72.
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1994: Dent G; Giembycz M A; Evans P M; Rabe K F; Barnes P J
Suppression of human eosinophil respiratory burst and cyclic AMP hydrolysis by inhibitors of type IV phosphodiesterase: interaction with the beta adrenoceptor agonist albuterol.
The Journal of pharmacology and experimental therapeutics 1994;271(3):1167-74.
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1994: Takahashi T; Belvisi M G; Patel H; Ward J K; Tadjkarimi S; Yacoub M H; Barnes P J
Effect of Ba 679 BR, a novel long-acting anticholinergic agent, on cholinergic neurotransmission in guinea pig and human airways.
American journal of respiratory and critical care medicine 1994;150(6 Pt 1):1640-5.
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1994: Ramnarine S I; Hirayama Y; Barnes P J; Rogers D F
'Sensory-efferent' neural control of mucus secretion: characterization using tachykinin receptor antagonists in ferret trachea in vitro.
British journal of pharmacology 1994;113(4):1183-90.
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1994: Adcock I M; Brown C R; Shirasaki H; Barnes P J
Effects of dexamethasone on cytokine and phorbol ester stimulated c-Fos and c-Jun DNA binding and gene expression in human lung.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1994;7(12):2117-23.
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1994: Barnes P J
Cytokines as mediators of chronic asthma.
American journal of respiratory and critical care medicine 1994;150(5 Pt 2):S42-9.
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1994: Kroegel C; Giembycz M A; Matthys H; Westwick J; Barnes P J
Modulatory role of protein kinase C on the signal transduction pathway utilized by platelet-activating factor in eosinophil activation.
American journal of respiratory cell and molecular biology 1994;11(5):593-9.
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1994: O'Connor B J; Yeo C T; Chen-Worsdell Y M; Barnes P J; Chung K F
Effect of acetazolamide and amiloride against sodium metabisulphite-induced bronchoconstriction in mild asthma.
Thorax 1994;49(11):1096-8.
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1994: Kwon O J; Au B T; Collins P D; Adcock I M; Mak J C; Robbins R R; Chung K F; Barnes P J
Tumor necrosis factor-induced interleukin-8 expression in cultured human airway epithelial cells.
The American journal of physiology 1994;267(4 Pt 1):L398-405.
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1994: Tsukagoshi H; Robbins R A; Barnes P J; Chung K F
Role of nitric oxide and superoxide anions in interleukin-1 beta-induced airway hyperresponsiveness to bradykinin.
American journal of respiratory and critical care medicine 1994;150(4):1019-25.
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1994: Barnes P J
Endothelins and pulmonary diseases.
Journal of applied physiology (Bethesda, Md. : 1985) 1994;77(3):1051-9.
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1994: Mak J C; Grandordy B; Barnes P J
High affinity [3H]formoterol binding sites in lung: characterization and autoradiographic mapping.
European journal of pharmacology 1994;269(1):35-41.
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1994: O'Connor B J; Fuller R W; Barnes P J
Nonbronchodilator effects of inhaled beta 2 agonists. Greater protection against adenosine monophosphate- than methacholine-induced bronchoconstriction in asthma.
American journal of respiratory and critical care medicine 1994;150(2):381-7.
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1994: Baraniuk J N; Silver P B; Kaliner M A; Barnes P J
Effects of ipratropium bromide on bradykinin nasal provocation in chronic allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1994;24(8):724-9.
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1994: Robbins R A; Barnes P J; Springall D R; Warren J B; Kwon O J; Buttery L D; Wilson A J; Geller D A; Polak J M
Expression of inducible nitric oxide in human lung epithelial cells.
Biochemical and biophysical research communications 1994;203(1):209-18.
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1994: O'Connor B J; Uden S; Carty T J; Eskra J D; Barnes P J; Chung K F
Inhibitory effect of UK,74505, a potent and specific oral platelet activating factor (PAF) receptor antagonist, on airway and systemic responses to inhaled PAF in humans.
American journal of respiratory and critical care medicine 1994;150(1):35-40.
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1994: Haczku A; Moqbel R; Elwood W; Sun J; Kay A B; Barnes P J; Chung K F
Effects of prolonged repeated exposure to ovalbumin in sensitized brown Norway rats.
American journal of respiratory and critical care medicine 1994;150(1):23-7.
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1994: Shirasaki H; Adcock I M; Kwon O J; Nishikawa M; Mak J C; Barnes P J
Agonist-induced up-regulation of platelet-activating factor receptor messenger RNA in human monocytes.
European journal of pharmacology 1994;268(2):263-6.
-
1994: Sun J; Elwood W; Haczku A; Barnes P J; Hellewell P G; Chung K F
Contribution of intercellular-adhesion molecule-1 in allergen-induced airway hyperresponsiveness and inflammation in sensitised brown-Norway rats.
International archives of allergy and immunology 1994;104(3):291-5.
-
1994: Haddad E B; Mak J C; Hislop A; Haworth S G; Barnes P J
Characterization of muscarinic receptor subtypes in pig airways: radioligand binding and northern blotting studies.
The American journal of physiology 1994;266(6 Pt 1):L642-8.
-
1994: Haddad E B; Mak J C; Barnes P J
Characterization of [3H]Ba 679 BR, a slowly dissociating muscarinic antagonist, in human lung: radioligand binding and autoradiographic mapping.
Molecular pharmacology 1994;45(5):899-907.
-
1994: Shirasaki H; Nishikawa M; Adcock I M; Mak J C; Sakamoto T; Shimizu T; Barnes P J
Expression of platelet-activating factor receptor mRNA in human and guinea pig lung.
American journal of respiratory cell and molecular biology 1994;10(5):533-7.
-
1994: Barnes P J
Air pollution and asthma.
Postgraduate medical journal 1994;70(823):319-25.
-
1994: Adcock I M; Brown C R; Barnes P J
Dexamethasone action on c-fos and c-jun mRNA and protein in human lung.
Biochemical Society transactions 1994;22(2):187S.
-
1994: Adcock I M; Liu S; Brown C R; Evans T W; Barnes P J
Endotoxin and steroid effects of nitric oxide synthase mRNA expression in rat lung and other tissues.
Biochemical Society transactions 1994;22(2):188S.
-
1994: Adcock I M; Brown C R; Kwon O; Barnes P J
Oxidative stress induces NF kappa B DNA binding and inducible NOS mRNA in the human epithelial cell line A549.
Biochemical Society transactions 1994;22(2):186S.
-
1994: O'Connor B J; Barnes P J; Chung K F
Inhibition of sodium metabisulphite induced bronchoconstriction by frusemide in asthma: role of cyclooxygenase products.
Thorax 1994;49(4):307-11.
-
1994: Ward J K; Fox A J; Barnes P J; Belvisi M G
Inhibition of excitatory non-adrenergic non-cholinergic bronchoconstriction in guinea-pig airways in vitro by activation of an atypical 5-HT receptor.
British journal of pharmacology 1994;111(4):1095-102.
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1994: Takahashi T; Belvisi M G; Barnes P J
Modulation of neurotransmission in guinea-pig airways by galanin and the effect of a new antagonist galantide.
Neuropeptides 1994;26(4):245-51.
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1994: Kwon O J; Au B T; Collins P D; Baraniuk J N; Adcock I M; Chung K F; Barnes P J
Inhibition of interleukin-8 expression by dexamethasone in human cultured airway epithelial cells.
Immunology 1994;81(3):389-94.
-
1994: Barnes P J; Pauwels R A
Theophylline in the management of asthma: time for reappraisal?
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1994;7(3):579-91.
-
1994: Liu S; Kuo H P; Sheppard M N; Barnes P J; Evans T W
Vagal stimulation induces increased pulmonary vascular permeability in guinea pig.
American journal of respiratory and critical care medicine 1994;149(3 Pt 1):744-50.
-
1994: Adcock I M; Brown C R; Kwon O; Barnes P J
Oxidative stress induces NF kappa B DNA binding and inducible NOS mRNA in human epithelial cells.
Biochemical and biophysical research communications 1994;199(3):1518-24.
-
1994: Sakamoto T; Tsukagoshi H; Barnes P J; Chung K F
Involvement of tachykinin receptors (NK1 and NK2) in sodium metabisulfite-induced airway effects.
American journal of respiratory and critical care medicine 1994;149(2 Pt 1):387-91.
-
1994: Tsukagoshi H; Sakamoto T; Xu W; Barnes P J; Chung K F
Effect of interleukin-1 beta on airway hyperresponsiveness and inflammation in sensitized and nonsensitized Brown-Norway rats.
The Journal of allergy and clinical immunology 1994;93(2):464-9.
-
1994: Rabe K F; Perkins R S; Dent G; Gustmann H; Barnes P J
Inhibitory effects of sulfonated shale oil fractions on the oxidative burst and Ca++ mobilization in stimulated macrophages.
Arzneimittel-Forschung 1994;44(2):166-70.
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1994: Nishikawa M; Mak J C; Shirasaki H; Harding S E; Barnes P J
Long-term exposure to norepinephrine results in down-regulation and reduced mRNA expression of pulmonary beta-adrenergic receptors in guinea pigs.
American journal of respiratory cell and molecular biology 1994;10(1):91-9.
-
1994: Sakamoto T; Sun J; Barnes P J; Chung K F
Effect of a bradykinin receptor antagonist, HOE 140, against bradykinin- and vagal stimulation-induced airway responses in the guinea-pig.
European journal of pharmacology 1994;251(2-3):137-42.
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1994: Kharitonov S A; Yates D; Robbins R A; Logan-Sinclair R; Shinebourne E A; Barnes P J
Increased nitric oxide in exhaled air of asthmatic patients.
Lancet 1994;343(8890):133-5.
-
1994: Baraniuk J N; Silver P B; Kaliner M A; Barnes P J
Perennial rhinitis subjects have altered vascular, glandular, and neural responses to bradykinin nasal provocation.
International archives of allergy and immunology 1994;103(2):202-8.
-
1994: Elwood W; Sakamoto T; Barnes P J; Chung K F
Role of cyclooxygenase and 5-lipoxygenase metabolites, platelet-activating factor and 5-hydroxytryptamine in allergen-induced airway responses in the brown Norway rat.
International archives of allergy and immunology 1994;103(1):67-72.
-
1994: Adcock I M; Shirasaki H; Gelder C M; Peters M J; Brown C R; Barnes P J
The effects of glucocorticoids on phorbol ester and cytokine stimulated transcription factor activation in human lung.
Life sciences 1994;55(14):1147-53.
-
1994: Grandordy B M; Mak J C; Barnes P J
Modulation of airway smooth muscle beta-adrenoceptor function by a muscarinic agonist.
Life sciences 1994;54(3):185-91.
-
1993: Barnes P J; Adcock I
Anti-inflammatory actions of steroids: molecular mechanisms.
Trends in pharmacological sciences 1993;14(12):436-41.
-
1993: Liu S; Adcock I M; Old R W; Barnes P J; Evans T W
Lipopolysaccharide treatment in vivo induces widespread tissue expression of inducible nitric oxide synthase mRNA.
Biochemical and biophysical research communications 1993;196(3):1208-13.
-
1993: Nishikawa M; Mak J C; Shirasaki H; Barnes P J
Differential down-regulation of pulmonary beta 1- and beta 2-adrenoceptor messenger RNA with prolonged in vivo infusion of isoprenaline.
European journal of pharmacology 1993;247(2):131-8.
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1993: Njuki F; Nicholl C G; Howard A; Mak J C; Barnes P J; Girgis S I; Legon S
A new calcitonin-receptor-like sequence in rat pulmonary blood vessels.
Clinical science (London, England : 1979) 1993;85(4):385-8.
-
1993: Barnes P J; Pedersen S
Efficacy and safety of inhaled corticosteroids in asthma. Report of a workshop held in Eze, France, October 1992.
The American review of respiratory disease 1993;148(4 Pt 2):S1-26.
-
1993: Barnes P J; Belvisi M G
Nitric oxide and lung disease.
Thorax 1993;48(10):1034-43.
-
1993: Sun J; Elwood W; Barnes P J; Chung K F
Effect of thiazide diuretics against neurally mediated contraction of guinea pig airways. Contribution of carbonic anhydrase.
The American review of respiratory disease 1993;148(4 Pt 1):902-8.
-
1993: Hayes J P; Barnes P J; Taylor A J; Chung K F
Effect of a topical corticosteroid on airway hyperresponsiveness and eosinophilic inflammation induced by trimellitic anhydride exposure in sensitized guinea pigs.
The Journal of allergy and clinical immunology 1993;92(3):450-6.
-
1993: Fox A J; Barnes P J; Urban L; Dray A
An in vitro study of the properties of single vagal afferents innervating guinea-pig airways.
The Journal of physiology 1993;469():21-35.
-
1993: Sakamoto T; Barnes P J; Chung K F
Effect of beta 2-adrenoceptor agonists against platelet-activating factor-induced airway microvascular leakage and bronchoconstriction in the guinea pig.
Agents and actions 1993;40(1-2):50-6.
-
1993: Miyayasu K; Mak J C; Nishikawa M; Barnes P J
Characterization of guinea pig pulmonary neurokinin type 1 receptors using a novel antagonist ligand, [3H]FK888.
Molecular pharmacology 1993;44(3):539-44.
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1993: Ward J K; Belvisi M G; Fox A J; Miura M; Tadjkarimi S; Yacoub M H; Barnes P J
Modulation of cholinergic neural bronchoconstriction by endogenous nitric oxide and vasoactive intestinal peptide in human airways in vitro.
The Journal of clinical investigation 1993;92(2):736-42.
-
1993: Adcock I M; Peters M; Gelder C; Shirasaki H; Brown C R; Barnes P J
Increased tachykinin receptor gene expression in asthmatic lung and its modulation by steroids.
Journal of molecular endocrinology 1993;11(1):1-7.
-
1993: Lei Y H; Barnes P J; Rogers D F
Inhibition of neurogenic plasma exudation and bronchoconstriction by a K+ channel activator, BRL 38227, in guinea pig airways in vivo.
European journal of pharmacology 1993;239(1-3):257-9.
-
1993: Adcock I M; Peters M J; Brown C R; Gelder C M; Barnes P J
Transcription factor interactions in human lung.
Biochemical Society transactions 1993;21 ( Pt 3)(3):277S.
-
1993: Barnes P J
Effect of nedocromil sodium on microvascular leakage.
The Journal of allergy and clinical immunology 1993;92(1 Pt 2):197-9.
-
1993: Barnes P J
Effect of nedocromil sodium on platelet-activating factor-induced airway responses.
The Journal of allergy and clinical immunology 1993;92(1 Pt 2):187-9.
-
1993: Barnes P J
Effect of nedocromil sodium on airway sensory nerves.
The Journal of allergy and clinical immunology 1993;92(1 Pt 2):182-6.
-
1993: Elwood W; Sakamoto T; Barnes P J; Chung K F
Allergen-induced airway hyperresponsiveness in Brown-Norway rat: role of parasympathetic mechanisms.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;75(1):279-84.
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1993: Sakamoto T; Tsukagoshi H; Barnes P J; Chung K F
Role played by NK2 receptor and cyclooxygenase activation in bradykinin B2 receptor mediated-airway effects in guinea pigs.
Agents and actions 1993;39(3-4):111-7.
-
1993: Watson N; Maclagan J; Barnes P J
Endogenous tachykinins facilitate transmission through parasympathetic ganglia in guinea-pig trachea.
British journal of pharmacology 1993;109(3):751-9.
-
1993: Stone R A; Barnes P J; Chung K F
Effect of frusemide on cough responses to chloride-deficient solution in normal and mild asthmatic subjects.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1993;6(6):862-7.
-
1993: McCormack D G; Rees R G; Crawley D; Barnes P J; Evans T W
Sensory neuropeptides and hypoxic pulmonary vasoconstriction in the rat.
Thorax 1993;48(5):554-7.
-
1993: Watson N; Maclagan J; Barnes P J
Vagal control of guinea pig tracheal smooth muscle: lack of involvement of VIP or nitric oxide.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;74(4):1964-71.
-
1993: Kroegel C; Dewar A; Yukawa T; Venge P; Barnes P J; Chung K F
Ultrastructural characterization of platelet-activating factor-stimulated human eosinophils from patients with asthma.
Clinical science (London, England : 1979) 1993;84(4):391-9.
-
1993: Sakamoto T; Elwood W; Barnes P J; Chung K F
Effect of inhaled lyso-platelet-activating factor on airway microvascular leakage in the guinea pig.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;74(3):1117-22.
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1993: Miura M; Belvisi M G; Ward J K; Tadjkarimi S; Yacoub M H; Barnes P J
Bronchodilating effects of the novel potassium channel opener HOE 234 in human airways in vitro.
British journal of clinical pharmacology 1993;35(3):318-20.
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1993: Verleden G M; Belvisi M G; Rabe K F; Miura M; Barnes P J
Beta 2-adrenoceptor agonists inhibit NANC neural bronchoconstrictor responses in vitro.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;74(3):1195-9.
-
1993: Hirayama Y; Lei Y H; Barnes P J; Rogers D F
Effects of two novel tachykinin antagonists, FK224 and FK888, on neurogenic airway plasma exudation, bronchoconstriction and systemic hypotension in guinea-pigs in vivo.
British journal of pharmacology 1993;108(3):844-51.
-
1993: Elwood W; Lötvall J O; Barnes P J; Chung K F
Airway hyperresponsiveness to acetylcholine and to tachykinins after respiratory virus infection in the guinea pig.
Annals of allergy 1993;70(3):231-6.
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1993: Kidney J C; Fuller R W; Worsdell Y M; Lavender E A; Chung K F; Barnes P J
Effect of an oral potassium channel activator, BRL 38227, on airway function and responsiveness in asthmatic patients: comparison with oral salbutamol.
Thorax 1993;48(2):130-3.
-
1993: Evans P M; O'Connor B J; Fuller R W; Barnes P J; Chung K F
Effect of inhaled corticosteroids on peripheral blood eosinophil counts and density profiles in asthma.
The Journal of allergy and clinical immunology 1993;91(2):643-50.
-
1993: Ring P C; Seldon P M; Barnes P J; Giembycz M A
Pharmacological characterization of a receptor for platelet-activating factor on guinea pig peritoneal macrophages using [3H]apafant, a selective and competitive platelet-activating factor antagonist: evidence that the noncompetitive behavior of apafant in functional studies relates to slow kinetics of dissociation.
Molecular pharmacology 1993;43(2):302-12.
-
1993: Rabe K F; Giembycz M A; Dent G; Perkins R S; Evans P; Barnes P J
Salmeterol is a competitive antagonist at beta-adrenoceptors mediating inhibition of respiratory burst in guinea-pig eosinophils.
European journal of pharmacology 1993;231(2):305-8.
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1993: O'Connor B J; Lecomte J M; Barnes P J
Effect of an inhaled histamine H3-receptor agonist on airway responses to sodium metabisulphite in asthma.
British journal of clinical pharmacology 1993;35(1):55-7.
-
1993: Stone R A; Worsdell Y M; Fuller R W; Barnes P J
Effects of 5-hydroxytryptamine and 5-hydroxytryptophan infusion on the human cough reflex.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;74(1):396-401.
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1993: Baraniuk J N; Ohkubo K; Kwon O J; Mak J; Rohde J; Kaliner M A; Durham S R; Barnes P J
Identification of neutral endopeptidase mRNA in human nasal mucosa.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;74(1):272-9.
-
1993: Kidney J C; Ridge S M; Chung K F; Barnes P J
Inhibition of platelet-activating factor-induced bronchoconstriction by the leukotriene D4 receptor antagonist ICI 204,219.
The American review of respiratory disease 1993;147(1):215-7.
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1993: Belvisi M G; Miura M; Stretton D; Barnes P J
Endogenous vasoactive intestinal peptide and nitric oxide modulate cholinergic neurotransmission in guinea-pig trachea.
European journal of pharmacology 1993;231(1):97-102.
-
1993: Sakamoto T; Barnes P J; Chung K F
Effect of CP-96,345, a non-peptide NK1 receptor antagonist, against substance P-, bradykinin- and allergen-induced airway microvascular leakage and bronchoconstriction in the guinea pig.
European journal of pharmacology 1993;231(1):31-8.
-
1993: Rogers D F; Alton E W; Dewar A; Lethem M I; Barnes P J
Impaired stimulus-evoked mucus secretion in cystic fibrosis bronchi.
Experimental lung research 1993;19(1):37-53.
-
1993: Lei Y H; Barnes P J; Rogers D F
Regulation of NANC neural bronchoconstriction in vivo in the guinea-pig: involvement of nitric oxide, vasoactive intestinal peptide and soluble guanylyl cyclase.
British journal of pharmacology 1993;108(1):228-35.
-
1993: Mak J C; Haddad E B; Buckley N J; Barnes P J
Visualization of muscarinic m4 mRNA and M4 receptor subtype in rabbit lung.
Life sciences 1993;53(19):1501-8.
-
1993: Barnes P J
Beta-adrenoceptors on smooth muscle, nerves and inflammatory cells.
Life sciences 1993;52(26):2101-9.
-
1993: Dent G; Barnes P J
Platelet activating factor stimulates a receptor-coupled membrane GTPase in guinea pig eosinophils.
Life sciences 1993;52(20):1633-40.
-
1992: Alton E W; Rogers D F; Logan-Sinclair R; Yacoub M; Barnes P J; Geddes D M
Bioelectric properties of cystic fibrosis airways obtained at heart-lung transplantation.
Thorax 1992;47(12):1010-4.
-
1992: Hirst S J; Barnes P J; Twort C H
Quantifying proliferation of cultured human and rabbit airway smooth muscle cells in response to serum and platelet-derived growth factor.
American journal of respiratory cell and molecular biology 1992;7(6):574-81.
-
1992: Barnes P J; Lee T H
Recent advances in asthma.
Postgraduate medical journal 1992;68(806):942-53.
-
1992: Belvisi M G; Stretton C D; Miura M; Verleden G M; Tadjkarimi S; Yacoub M H; Barnes P J
Inhibitory NANC nerves in human tracheal smooth muscle: a quest for the neurotransmitter.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;73(6):2505-10.
-
1992: Barnes P J
Bradykinin and asthma.
Thorax 1992;47(11):979-83.
-
1992: Hayes J P; Daniel R; Tee R D; Barnes P J; Taylor A J; Chung K F
Bronchial hyperreactivity after inhalation of trimellitic anhydride dust in guinea pigs after intradermal sensitization to the free hapten.
The American review of respiratory disease 1992;146(5 Pt 1):1311-4.
-
1992: Hayes J P; Lotvall J O; Baraniuk J; Daniel R; Barnes P J; Taylor A J; Chung K F
Bronchoconstriction and airway microvascular leakage in guinea pigs sensitized with trimellitic anhydride.
The American review of respiratory disease 1992;146(5 Pt 1):1306-10.
-
1992: Liu S F; Crawley D E; Rohde J A; Evans T W; Barnes P J
Role of nitric oxide and guanosine 3',5'-cyclic monophosphate in mediating nonadrenergic, noncholinergic relaxation in guinea-pig pulmonary arteries.
British journal of pharmacology 1992;107(3):861-6.
-
1992: Baraniuk J N; Silver P B; Kaliner M A; Barnes P J
Neuropeptide Y is a vasoconstrictor in human nasal mucosa.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;73(5):1867-72.
-
1992: Hui K P; Lötvall J; Rogers D F; Barnes P J; Chung F K
Ovalbumin aerosol challenge in actively sensitized guinea pigs: relationship between airway microvascular leakage and airflow obstruction.
Allergy 1992;47(5):527-31.
-
1992: Kuo H P; Liu S; Barnes P J
The effect of endogenous nitric oxide on neurogenic plasma exudation in guinea-pig airways.
European journal of pharmacology 1992;221(2-3):385-8.
-
1992: Barnes P J
New drugs for asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1992;5(9):1126-36.
-
1992: O'Connor B J; Aikman S L; Barnes P J
Tolerance to the nonbronchodilator effects of inhaled beta 2-agonists in asthma.
The New England journal of medicine 1992;327(17):1204-8.
-
1992: Stone R A; Barnes P J; Fuller R W
The low-chloride cough response is not inhibited by a single, high dose of aspirin.
British journal of clinical pharmacology 1992;34(4):370-2.
-
1992: Miura M; Belvisi M G; Barnes P J
Effect of bradykinin on airway neural responses in vitro.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;73(4):1537-41.
-
1992: Sakamoto T; Elwood W; Barnes P J; Chung K F
Pharmacological modulation of inhaled sodium metabisulphite-induced airway microvascular leakage and bronchoconstriction in the guinea-pig.
British journal of pharmacology 1992;107(2):481-7.
-
1992: Mak J C; Baraniuk J N; Barnes P J
Localization of muscarinic receptor subtype mRNAs in human lung.
American journal of respiratory cell and molecular biology 1992;7(3):344-8.
-
1992: O'Connor B J; Ridge S M; Barnes P J; Fuller R W
Greater effect of inhaled budesonide on adenosine 5'-monophosphate-induced than on sodium-metabisulfite-induced bronchoconstriction in asthma.
The American review of respiratory disease 1992;146(3):560-4.
-
1992: Crawley D E; Zhao L; Giembycz M A; Liu S; Barnes P J; Winter R J; Evans T W
Chronic hypoxia impairs soluble guanylyl cyclase-mediated pulmonary arterial relaxation in the rat.
The American journal of physiology 1992;263(3 Pt 1):L325-32.
-
1992: Miura M; Belvisi M G; Stretton C D; Yacoub M H; Barnes P J
Role of K+ channels in the modulation of cholinergic neural responses in guinea-pig and human airways.
The Journal of physiology 1992;455():1-15.
-
1992: Kuo H P; Rohde J A; Barnes P J; Rogers D F
Cigarette smoke-induced airway goblet cell secretion: dose-dependent differential nerve activation.
The American journal of physiology 1992;263(2 Pt 1):L161-7.
-
1992: Stone R; Barnes P J; Fuller R W
Contrasting effects of prostaglandins E2 and F2 alpha on sensitivity of the human cough reflex.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;73(2):649-53.
-
1992: Hayes J P; Lotvall J O; Barnes P J; Newman Taylor A J; Chung K F
Involvement of inflammatory mediators in the airway responses to trimellitic anhydride in sensitized guinea-pigs.
British journal of pharmacology 1992;106(4):828-32.
-
1992: Hayes J P; Daniel R; Tee R D; Barnes P J; Chung K F; Newman Taylor A J
Specific immunological and bronchopulmonary responses following intradermal sensitization to free trimellitic anhydride in guinea pigs.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1992;22(7):694-700.
-
1992: Miura M; Belvisi M G; Stretton C D; Yacoub M H; Barnes P J
Role of potassium channels in bronchodilator responses in human airways.
The American review of respiratory disease 1992;146(1):132-6.
-
1992: Barnes P J
Modulation of neurotransmission in airways.
Physiological reviews 1992;72(3):699-729.
-
1992: Elwood W; Lötvall J O; Barnes P J; Chung K F
Effect of dexamethasone and cyclosporin A on allergen-induced airway hyperresponsiveness and inflammatory cell responses in sensitized Brown-Norway rats.
The American review of respiratory disease 1992;145(6):1289-94.
-
1992: Barnes P J
PAF, eosinophils and asthma.
Journal of lipid mediators 1992;5(2):155-8.
-
1992: Liu S F; Hislop A A; Haworth S G; Barnes P J
Developmental changes in endothelium-dependent pulmonary vasodilatation in pigs.
British journal of pharmacology 1992;106(2):324-30.
-
1992: Lötvall J; Elwood W; Tokuyama K; Sakamoto T; Barnes P J; Chung K F
A thromboxane mimetic, U-46619, produces plasma exudation in airways of the guinea pig.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;72(6):2415-9.
-
1992: Perkins R S; Dent G; Chung K F; Barnes P J
The effect of anion transport inhibitors and extracellular Cl- concentration on eosinophil respiratory burst activity.
Biochemical pharmacology 1992;43(11):2480-3.
-
1992: Barnes P J
New aspects of asthma.
Journal of internal medicine 1992;231(5):453-61.
-
1992: Baraniuk J N; Silver P B; Kaliner M A; Barnes P J
Ibuprofen augments bradykinin-induced glycoconjugate secretion by human nasal mucosa in vivo.
The Journal of allergy and clinical immunology 1992;89(5):1032-9.
-
1992: Ventresca P G; Nichol G M; Barnes P J; Chung K F
Effect of frusemide on the induction and potentiation of cough induced by prostaglandin F2 alpha.
British journal of clinical pharmacology 1992;33(5):514-6.
-
1992: Hui K P; Ventresca P; Brown A C; Barnes P J; Chung K F
Modulation of neurally mediated airway microvascular leakage in guinea-pig airways by beta 2-adrenoceptor agonists.
Agents and actions 1992;36(1-2):29-32.
-
1992: Belvisi M G; Miura M; Stretton D; Barnes P J
Capsazepine as a selective antagonist of capsaicin-induced activation of C-fibres in guinea-pig bronchi.
European journal of pharmacology 1992;215(2-3):341-4.
-
1992: Kuo H P; Rohde J A; Barnes P J; Rogers D F
K+ channel activator inhibition of neurogenic goblet cell secretion in guinea pig trachea.
European journal of pharmacology 1992;215(2-3):297-9.
-
1992: Barnes P J
Molecular biology of receptors.
The Quarterly journal of medicine 1992;83(301):339-53.
-
1992: Crawley D E; Liu S F; Barnes P J; Evans T W
Endothelin-3 is a potent pulmonary vasodilator in the rat.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;72(4):1425-31.
-
1992: Liu S F; Dewar A; Crawley D E; Barnes P J; Evans T W
Effect of tumor necrosis factor on hypoxic pulmonary vasoconstriction.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;72(3):1044-9.
-
1992: McCormack D G; Crawley D E; Barnes P J; Evans T W
Bleomycin-induced lung injury in rats selectively abolishes hypoxic pulmonary vasoconstriction: evidence against a role for platelet-activating factor.
Clinical science (London, England : 1979) 1992;82(3):259-64.
-
1992: Sakamoto T; Elwood W; Barnes P J; Chung K F
Effect of Hoe 140, a new bradykinin receptor antagonist, on bradykinin- and platelet-activating factor-induced bronchoconstriction and airway microvascular leakage in guinea pig.
European journal of pharmacology 1992;213(3):367-73.
-
1992: Belvisi M G; Stretton C D; Verleden G M; Ledingham S J; Yacoub M H; Barnes P J
Inhibition of cholinergic neurotransmission in human airways by opioids.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;72(3):1096-100.
-
1992: Stretton D; Belvisi M G; Barnes P J
The effect of sensory nerve depletion on cholinergic neurotransmission in guinea pig airways.
The Journal of pharmacology and experimental therapeutics 1992;260(3):1073-80.
-
1992: Liu S F; Crawley D E; Evans T W; Barnes P J
Endothelium-dependent nonadrenergic, noncholinergic neural relaxation in guinea pig pulmonary artery.
The Journal of pharmacology and experimental therapeutics 1992;260(2):541-8.
-
1992: Kuo H P; Rohde J A; Barnes P J; Rogers D F
Differential inhibitory effects of opioids on cigarette smoke, capsaicin and electrically-induced goblet cell secretion in guinea-pig trachea.
British journal of pharmacology 1992;105(2):361-6.
-
1992: Lei Y H; Barnes P J; Rogers D F
Inhibition of neurogenic plasma exudation in guinea-pig airways by CP-96,345, a new non-peptide NK1 receptor antagonist.
British journal of pharmacology 1992;105(2):261-2.
-
1992: Stretton D; Miura M; Belvisi M G; Barnes P J
Calcium-activated potassium channels mediate prejunctional inhibition of peripheral sensory nerves.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(4):1325-9.
-
1992: Baraniuk J N; Silver P B; Lundgren J D; Cole P; Kaliner M A; Barnes P J
Bombesin stimulates human nasal mucous and serous cell secretion in vivo.
The American journal of physiology 1992;262(1 Pt 1):L48-52.
-
1992: Chung K F; Barnes P J
Role of inflammatory mediators in asthma.
British medical bulletin 1992;48(1):135-48.
-
1992: Lötvall J; Rabe K; Tokuyama K; Löfdahl C G; Barnes P J; Chung K F
Neutrophil influx into guinea-pig airway lumen during cholinergic and non-cholinergic bronchoconstriction.
Acta physiologica Scandinavica 1992;144(1):101-6.
-
1992: Barnes P J
Asthma. New therapeutic approaches.
British medical bulletin 1992;48(1):231-47.
-
1992: Barnes P J
Neural mechanisms in asthma.
British medical bulletin 1992;48(1):149-68.
-
1992: Belvisi M G; Stretton C D; Yacoub M; Barnes P J
Nitric oxide is the endogenous neurotransmitter of bronchodilator nerves in humans.
European journal of pharmacology 1992;210(2):221-2.
-
1992: Barnes P J; Chung K F
Questions about inhaled beta 2-adrenoceptor agonists in asthma.
Trends in pharmacological sciences 1992;13(1):20-3.
-
1992: Chung K F; Barnes P J
Loop diuretics and asthma.
Pulmonary pharmacology 1992;5(1):1-7.
-
1992: Elwood W; Barnes P J; Chung K F
Airway hyperresponsiveness is associated with inflammatory cell infiltration in allergic brown-Norway rats.
International archives of allergy and immunology 1992;99(1):91-7.
-
1992: Barnes P J
Effect of bradykinin on airway function.
Agents and actions. Supplements 1992;38 ( Pt 3)():432-8.
-
1992: Nichol G M; O'Connor B J; Lecomte J M; Chung K F; Barnes P J
Effect of neutral endopeptidase inhibitor on airway function and bronchial responsiveness in asthmatic subjects.
European journal of clinical pharmacology 1992;42(5):491-4.
-
1992: Barnes P J
Neurogenic inflammation and asthma.
The Journal of asthma : official journal of the Association for the Care of Asthma 1992;29(3):165-80.
-
1992: Rabe K F; Giembycz M A; Dent G; Barnes P J
Activation of guinea pig eosinophil respiratory burst by leukotriene B4: role of protein kinase C.
Fundamental & clinical pharmacology 1992;6(8-9):353-8.
-
1991: Chung K F; Barnes P J
Role for platelet-activating factor in asthma.
Lipids 1991;26(12):1277-9.
-
1991: Elwood W; Lötvall J O; Barnes P J; Chung K F
Characterization of allergen-induced bronchial hyperresponsiveness and airway inflammation in actively sensitized brown-Norway rats.
The Journal of allergy and clinical immunology 1991;88(6):951-60.
-
1991: Barnes P J; Baraniuk J N; Belvisi M G
Neuropeptides in the respiratory tract. Part II.
The American review of respiratory disease 1991;144(6):1391-9.
-
1991: Lötvall J O; Elwood W; Tokuyama K; Barnes P J; Chung K F
Differential effects of phosphoramidon on neurokinin A- and substance P-induced airflow obstruction and airway microvascular leakage in guinea-pig.
British journal of pharmacology 1991;104(4):945-9.
-
1991: Tokuyama K; Lötvall J O; Morikawa A; Barnes P J; Chung K F
Role of thromboxane A2 in airway microvascular leakage induced by inhaled platelet-activating factor.
Journal of applied physiology (Bethesda, Md. : 1985) 1991;71(5):1729-34.
-
1991: Hamid Q; Belvisi M G; Stretton D; Rohde J; Harmar A J; Barnes P J
Localization of beta pre-protachykinin mRNA in nodose ganglion.
Neuropeptides 1991;20(3):145-50.
-
1991: Barnes P J; Baraniuk J N; Belvisi M G
Neuropeptides in the respiratory tract. Part I.
The American review of respiratory disease 1991;144(5):1187-98.
-
1991: Shock A; Rabe K F; Dent G; Chambers R C; Gray A J; Chung K F; Barnes P J; Laurent G J
Eosinophils adhere to and stimulate replication of lung fibroblasts 'in vitro'.
Clinical and experimental immunology 1991;86(1):185-90.
-
1991: Barnes P J
Biochemistry of asthma.
Trends in biochemical sciences 1991;16(10):365-9.
-
1991: Liu S F; Crawley D E; Evans T W; Barnes P J
Endogenous nitric oxide modulates adrenergic neural vasoconstriction in guinea-pig pulmonary artery.
British journal of pharmacology 1991;104(2):565-9.
-
1991: Morgan J M; McCormack D G; Griffiths M J; Morgan C J; Barnes P J; Evans T W
Adenosine as a vasodilator in primary pulmonary hypertension.
Circulation 1991;84(3):1145-9.
-
1991: Barnes P J
Preventative therapy in adults with asthma.
Respiratory medicine 1991;85(5):355-7.
-
1991: Lötvall J O; Tokuyama K; Barnes P J; Chung K F
Bradykinin-induced airway microvascular leakage is potentiated by captopril and phosphoramidon.
European journal of pharmacology 1991;200(2-3):211-7.
-
1991: Belvisi M G; Stretton C D; Barnes P J
Bombesin-induced bronchoconstriction in the guinea pig: mode of action.
The Journal of pharmacology and experimental therapeutics 1991;258(1):36-41.
-
1991: Hayes J P; Ridge S M; Griffith S; Barnes P J; Chung K F
Inhibition of cutaneous and platelet responses to platelet-activating factor by oral WEB 2086 in man.
The Journal of allergy and clinical immunology 1991;88(1):83-8.
-
1991: Kroegel C; Chilvers E R; Giembycz M A; Challiss R A; Barnes P J
Platelet-activating factor stimulates a rapid accumulation of inositol (1,4,5)trisphosphate in guinea pig eosinophils: relationship to calcium mobilization and degranulation.
The Journal of allergy and clinical immunology 1991;88(1):114-24.
-
1991: Giembycz M A; Barnes P J
Selective inhibition of a high affinity type IV cyclic AMP phosphodiesterase in bovine trachealis by AH 21-132. Relevance to the spasmolytic and anti-spasmogenic actions of AH 21-132 in the intact tissue.
Biochemical pharmacology 1991;42(3):663-77.
-
1991: Tokuyama K; Lötvall J O; Barnes P J; Chung K F
Mechanism of airway narrowing caused by inhaled platelet-activating factor. Role of airway microvascular leakage.
The American review of respiratory disease 1991;143(6):1345-9.
-
1991: Elwood W; Lötvall J O; Barnes P J; Chung K F
Loop diuretics inhibit cholinergic and noncholinergic nerves in guinea pig airways.
The American review of respiratory disease 1991;143(6):1340-4.
-
1991: O'Connor B J; Chung K F; Chen-Worsdell Y M; Fuller R W; Barnes P J
Effect of inhaled furosemide and bumetanide on adenosine 5'-monophosphate- and sodium metabisulfite-induced bronchoconstriction in asthmatic subjects.
The American review of respiratory disease 1991;143(6):1329-33.
-
1991: Lötvall J O; Tokuyama K; Löfdahl C G; Ullman A; Barnes P J; Chung K F
Peptidase modulation of noncholinergic vagal bronchoconstriction and airway microvascular leakage.
Journal of applied physiology (Bethesda, Md. : 1985) 1991;70(6):2730-5.
-
1991: Dent G; Giembycz M A; Rabe K F; Barnes P J
Inhibition of eosinophil cyclic nucleotide PDE activity and opsonised zymosan-stimulated respiratory burst by 'type IV'-selective PDE inhibitors.
British journal of pharmacology 1991;103(2):1339-46.
-
1991: Belvisi M G; Stretton D; Barnes P J
Nitric oxide as an endogenous modulator of cholinergic neurotransmission in guinea-pig airways.
European journal of pharmacology 1991;198(2-3):219-21.
-
1991: Hui K P; Lötvall J; Chung K F; Barnes P J
Attenuation of inhaled allergen-induced airway microvascular leakage and airflow obstruction in guinea pigs by a 5-lipoxygenase inhibitor (A-63162).
The American review of respiratory disease 1991;143(5 Pt 1):1015-9.
-
1991: Boschetto P; Rogers D F; Fabbri L M; Barnes P J
Corticosteroid inhibition of airway microvascular leakage.
The American review of respiratory disease 1991;143(3):605-9.
-
1991: Hui K P; Taylor I K; Taylor G W; Rubin P; Kesterson J; Barnes N C; Barnes P J
Effect of a 5-lipoxygenase inhibitor on leukotriene generation and airway responses after allergen challenge in asthmatic patients.
Thorax 1991;46(3):184-9.
-
1991: Lötvall J O; Elwood W; Tokuyama K; Barnes P J; Chung K F
Plasma exudation into airways induced by inhaled platelet-activating factor: effect of peptidase inhibition.
Clinical science (London, England : 1979) 1991;80(3):241-7.
-
1991: Chung K F; Podgorski M R; Goulding N J; Godolphin J L; Sharland P R; O'Connor B; Flower R J; Barnes P J
Circulating autoantibodies to recombinant lipocortin-1 in asthma.
Respiratory medicine 1991;85(2):121-4.
-
1991: Stretton C D; Belvisi M G; Barnes P J
Modulation of neural bronchoconstrictor responses in the guinea pig respiratory tract by vasoactive intestinal peptide.
Neuropeptides 1991;18(3):149-57.
-
1991: Barnes P J
Neuropeptides and asthma.
The American review of respiratory disease 1991;143(3 Pt 2):S28-32.
-
1991: Lötvall J O; Hui K P; Löfdahl C G; Barnes P J; Chung K F
Capsaicin pretreatment does not inhibit allergen-induced airway microvascular leakage in guinea pig.
Allergy 1991;46(2):105-8.
-
1991: Mak J C; Barnes P J
Autoradiographic visualization of bradykinin receptors in human and guinea pig lung.
European journal of pharmacology 1991;194(1):37-43.
-
1991: Tokuyama K; Lötvall J O; Löfdahl C G; Barnes P J; Chung K F
Inhaled formoterol inhibits histamine-induced airflow obstruction and airway microvascular leakage.
European journal of pharmacology 1991;193(1):35-9.
-
1991: Liu S F; Crawley D E; Barnes P J; Evans T W
Endothelium-derived relaxing factor inhibits hypoxic pulmonary vasoconstriction in rats.
The American review of respiratory disease 1991;143(1):32-7.
-
1991: Verleden G M; Belvisi M G; Stretton C D; Barnes P J
Nedocromil sodium modulates nonadrenergic, noncholinergic bronchoconstrictor nerves in guinea pig airways in vitro.
The American review of respiratory disease 1991;143(1):114-8.
-
1991: Barnes P J
Managing asthma in hospital: cause for concern.
Postgraduate medical journal 1991;67(783):1-3.
-
1991: Barnes P J
Future drug therapy for asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1991;21 Suppl 1():80-5.
-
1991: Barnes P J
Sensory nerves, neuropeptides, and asthma.
Annals of the New York Academy of Sciences 1991;629():359-70.
-
1991: Barnes P J
Neurogenic inflammation in airways.
International archives of allergy and applied immunology 1991;94(1-4):303-9.
-
1991: Barnes P J
Platelet activating factor and asthma.
Annals of the New York Academy of Sciences 1991;629():193-204.
-
1991: Barnes P J
Histamine receptors in the lung.
Agents and actions. Supplements 1991;33():103-22.
-
1990: Lötvall J O; Skoogh B E; Lemen R J; Elwood W; Barnes P J; Chung K F
Bronchoconstriction induced by inhaled sodium metabisulfite in the guinea pig. Effect of capsaicin pretreatment and of neutral endopeptidase inhibition.
The American review of respiratory disease 1990;142(6 Pt 1):1390-5.
-
1990: McCormack D G; Barnes P J; Evans T W
Platelet-activating factor: evidence against a role in hypoxic pulmonary vasoconstriction.
Critical care medicine 1990;18(12):1398-402.
-
1990: Liu S F; Cai Y N; Evans T W; McCormack D G; Barer G R; Barnes P J
Ligustrazine is a vasodilator of human pulmonary and bronchial arteries.
European journal of pharmacology 1990;191(3):345-50.
-
1990: Barnes P J; Boschetto P; Rogers D F; Belvisi M; Roberts N; Chung K F; Evans T W
Effects of treatment on airway microvascular leakage.
The European respiratory journal. Supplement 1990;12():663s-670s; discussion 670s-671s.
-
1990: Rogers D F; Alton E W; Aursudkij B; Boschetto P; Dewar A; Barnes P J
Effect of platelet activating factor on formation and composition of airway fluid in the guinea-pig trachea.
The Journal of physiology 1990;431():643-58.
-
1990: Kuo H P; Rohde J A; Tokuyama K; Barnes P J; Rogers D F
Capsaicin and sensory neuropeptide stimulation of goblet cell secretion in guinea-pig trachea.
The Journal of physiology 1990;431():629-41.
-
1990: Stretton C D; Belvisi M G; Barnes P J
Neuropeptide Y modulates non-adrenergic, non-cholinergic neural bronchoconstriction in vivo and in vitro.
Neuropeptides 1990;17(4):163-70.
-
1990: Stretton C D; Mak J C; Belvisi M G; Yacoub M H; Barnes P J
Cholinergic control of human airways in vitro following extrinsic denervation of the human respiratory tract by heart-lung transplantation.
The American review of respiratory disease 1990;142(5):1030-3.
-
1990: Frossard N; Stretton C D; Barnes P J
Modulation of bradykinin responses in airway smooth muscle by epithelial enzymes.
Agents and actions 1990;31(3-4):204-9.
-
1990: Rogers D F; Alton E W; Dewar A; Geddes D M; Barnes P J
Tracheal potential difference in the reserpine and isoproterenol rat models of cystic fibrosis.
Experimental lung research 1990;16(6):661-70.
-
1990: Rogers D F; Dijk S; Barnes P J
Bradykinin-induced plasma exudation in guinea-pig airways: involvement of platelet activating factor.
British journal of pharmacology 1990;101(3):739-45.
-
1990: Chanez P; Dent G; Yukawa T; Barnes P J; Chung K F
Generation of oxygen free radicals from blood eosinophils from asthma patients after stimulation with PAF or phorbol ester.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1990;3(9):1002-7.
-
1990: Ichinose M; Barnes P J
Histamine H3 receptors modulate antigen-induced bronchoconstriction in guinea pigs.
The Journal of allergy and clinical immunology 1990;86(4 Pt 1):491-5.
-
1990: Lötvall J O; Lemen R J; Hui K P; Barnes P J; Chung K F
Airflow obstruction after substance P aerosol: contribution of airway and pulmonary edema.
Journal of applied physiology (Bethesda, Md. : 1985) 1990;69(4):1473-8.
-
1990: Kroegel C; Giembycz M A; Barnes P J
Characterization of eosinophil cell activation by peptides. Differential effects of substance P, melittin, and FMET-Leu-Phe.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(8):2581-7.
-
1990: Ichinose M; Barnes P J
The effect of peptidase inhibitors on bradykinin-induced bronchoconstriction in guinea-pigs in vivo.
British journal of pharmacology 1990;101(1):77-80.
-
1990: Crawley D E; Liu S F; Evans T W; Barnes P J
Inhibitory role of endothelium-derived relaxing factor in rat and human pulmonary arteries.
British journal of pharmacology 1990;101(1):166-70.
-
1990: Nichol G M; Alton E W; Nix A; Geddes D M; Chung K F; Barnes P J
Effect of inhaled furosemide on metabisulfite- and methacholine-induced bronchoconstriction and nasal potential difference in asthmatic subjects.
The American review of respiratory disease 1990;142(3):576-80.
-
1990: Nichol G; Nix A; Barnes P J; Chung K F
Prostaglandin F2 alpha enhancement of capsaicin induced cough in man: modulation by beta 2 adrenergic and anticholinergic drugs.
Thorax 1990;45(9):694-8.
-
1990: Stretton C D; Belvisi M G; Barnes P J
Sensory nerve depletion potentiates inhibitory non-adrenergic, non-cholinergic nerves in guinea-pig airways.
European journal of pharmacology 1990;184(2-3):333-7.
-
1990: Tokuyama K; Kuo H P; Rohde J A; Barnes P J; Rogers D F
Neural control of goblet cell secretion in guinea pig airways.
The American journal of physiology 1990;259(2 Pt 1):L108-15.
-
1990: Liu S F; Yacoub M; Barnes P J
Effect of histamine on human bronchial arteries in vitro.
Naunyn-Schmiedeberg's archives of pharmacology 1990;342(1):90-3.
-
1990: Ventresca P G; Nichol G M; Barnes P J; Chung K F
Inhaled furosemide inhibits cough induced by low chloride content solutions but not by capsaicin.
The American review of respiratory disease 1990;142(1):143-6.
-
1990: Mak J C; Barnes P J
Autoradiographic visualization of muscarinic receptor subtypes in human and guinea pig lung.
The American review of respiratory disease 1990;141(6):1559-68.
-
1990: Barnes P J
Molecular biology and respiratory disease. 5. Molecular biology of receptors: implications for lung disease.
Thorax 1990;45(6):482-8.
-
1990: Yukawa T; Ukena D; Kroegel C; Chanez P; Dent G; Chung K F; Barnes P J
Beta 2-adrenergic receptors on eosinophils. Binding and functional studies.
The American review of respiratory disease 1990;141(6):1446-52.
-
1990: Belvisi M G; Barnes P J; Rogers D F
Neurogenic inflammation in the airways: characterisation of electrical parameters for vagus nerve stimulation in the guinea pig.
Journal of neuroscience methods 1990;32(2):159-67.
-
1990: Ichinose M; Belvisi M G; Barnes P J
Bradykinin-induced bronchoconstriction in guinea pig in vivo: role of neural mechanisms.
The Journal of pharmacology and experimental therapeutics 1990;253(2):594-9.
-
1990: McCormack D G; Barnes P J; Evans T W
Effects of dopexamine hydrochloride on hypoxic pulmonary vasoconstriction in isolated rat lung.
Critical care medicine 1990;18(5):520-3.
-
1990: Barnes P J; Belvisi M G; Rogers D F
Modulation of neurogenic inflammation: novel approaches to inflammatory disease.
Trends in pharmacological sciences 1990;11(5):185-9.
-
1990: Giembycz M A; Kroegel C; Barnes P J
Platelet activating factor stimulates cyclo-oxygenase activity in guinea pig eosinophils. Concerted biosynthesis of thromboxane A2 and E-series prostaglandins.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(9):3489-97.
-
1990: Barnes P J
Muscarinic receptors in airways: recent developments.
Journal of applied physiology (Bethesda, Md. : 1985) 1990;68(5):1777-85.
-
1990: Belvisi M G; Stretton C D; Barnes P J
Modulation of cholinergic neurotransmission in guinea-pig airways by opioids.
British journal of pharmacology 1990;100(1):131-7.
-
1990: Yukawa T; Read R C; Kroegel C; Rutman A; Chung K F; Wilson R; Cole P J; Barnes P J
The effects of activated eosinophils and neutrophils on guinea pig airway epithelium in vitro.
American journal of respiratory cell and molecular biology 1990;2(4):341-53.
-
1990: Lammers J W; Kioumis I; McCusker M; Nichol G M; Barnes P J; Chung K F
Effects of prostacyclin on bronchoconstriction and neutropenia induced by inhaled platelet-activating factor in man.
The Journal of allergy and clinical immunology 1990;85(4):763-9.
-
1990: Evans T W; McAnulty R J; Rogers D F; Chung K F; Barnes P J; Laurent G J
Bleomycin-induced lung injury in the rat: effects of the platelet-activating factor (PAF) receptor antagonist BN 52021 and platelet depletion.
Environmental health perspectives 1990;85():65-9.
-
1990: Chung K F; Rogers D F; Barnes P J; Evans T W
The role of increased airway microvascular permeability and plasma exudation in asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1990;3(3):329-37.
-
1990: Minette P A; Barnes P J
Muscarinic receptor subtypes in lung. Clinical implications.
The American review of respiratory disease 1990;141(3 Pt 2):S162-5.
-
1990: Barnes P J
Airway smooth muscle receptors.
Recenti progressi in medicina 1990;81(3):184-92.
-
1990: Coupe M O; Mak J C; Yacoub M; Oldershaw P J; Barnes P J
Autoradiographic mapping of calcitonin gene-related peptide receptors in human and guinea pig hearts.
Circulation 1990;81(3):741-7.
-
1990: Ichinose M; Barnes P J
A potassium channel activator modulates both excitatory noncholinergic and cholinergic neurotransmission in guinea pig airways.
The Journal of pharmacology and experimental therapeutics 1990;252(3):1207-12.
-
1990: Nix A; Nichol G M; Robson A; Barnes P J; Chung K F
Effect of formoterol, a long-lasting beta 2-adrenoceptor agonist, against methacholine-induced bronchoconstriction.
British journal of clinical pharmacology 1990;29(3):321-4.
-
1990: Wardlaw A J; Chung K F; Moqbel R; MacDonald A J; Hartnell A; McCusker M; Collins J V; Barnes P J; Kay A B
Effects of inhaled PAF in humans on circulating and bronchoalveolar lavage fluid neutrophils. Relationship to bronchoconstriction and changes in airway responsiveness.
The American review of respiratory disease 1990;141(2):386-92.
-
1990: Kroegel C; Venge P; Matthys H; Barnes P J
[Degranulation of human eosinophilic granulocytes by the platelet activating factor]
Pneumologie (Stuttgart, Germany) 1990;44 Suppl 1():234-5.
-
1990: Barnes P J
Effect of corticosteroids on airway hyperresponsiveness.
The American review of respiratory disease 1990;141(2 Pt 2):S70-6.
-
1990: Mak J C; Barnes P J
Peripheral type benzodiazepine receptors in human and guinea pig lung: characterization and autoradiographic mapping.
The Journal of pharmacology and experimental therapeutics 1990;252(2):880-5.
-
1990: Barnes P J
Neurogenic inflammation in airways and its modulation.
Archives internationales de pharmacodynamie et de thérapie 1990;303():67-82.
-
1990: Ichinose M; Belvisi M G; Barnes P J
Histamine H3-receptors inhibit neurogenic microvascular leakage in airways.
Journal of applied physiology (Bethesda, Md. : 1985) 1990;68(1):21-5.
-
1990: Rhoden K J; Barnes P J
Potentiation of nonadrenergic neural relaxation in guinea pig airways by a cyclic cAMP phosphodiesterase inhibitor.
The Journal of pharmacology and experimental therapeutics 1990;252(1):396-402.
-
1990: Maxwell D L; Fuller R W; Dixon C M; Cuss F M; Barnes P J
Ventilatory effects of substance P, vasoactive intestinal peptide, and nitroprusside in humans.
Journal of applied physiology (Bethesda, Md. : 1985) 1990;68(1):295-301.
-
1990: Barnes P J
Reactive oxygen species and airway inflammation.
Free radical biology & medicine 1990;9(3):235-43.
-
1990: Barnes P J
Neural control of airway function: new perspectives.
Molecular aspects of medicine 1990;11(5):351-423.
-
1990: Barnes P J
Neuropeptides as modulators of airway function.
Agents and actions. Supplements 1990;31():175-96.
-
1990: Barnes P J
The role of neurotransmitters in bronchial asthma.
Lung 1990;168 Suppl():57-65.
-
1989: Crawley D; Evans T W; Barnes P J
Endothelin-1 constricts human pulmonary resistance vessels in vitro.
British journal of pharmacology 1989;98 Suppl():839P.
-
1989: Stretton C D; Belvisi M G; Barnes P J
Sensory nerve depletion potentiates non-adrenergic, non-cholinergic inhibitory nerves in guinea-pig trachea.
British journal of pharmacology 1989;98 Suppl():780P.
-
1989: Minette P A; Lammers J W; Dixon C M; McCusker M T; Barnes P J
A muscarinic agonist inhibits reflex bronchoconstriction in normal but not in asthmatic subjects.
Journal of applied physiology (Bethesda, Md. : 1985) 1989;67(6):2461-5.
-
1989: Warren J B; Maltby N H; MacCormack D; Barnes P J
Pulmonary endothelium-derived relaxing factor is impaired in hypoxia.
Clinical science (London, England : 1979) 1989;77(6):671-6.
-
1989: Liu S F; McCormack D G; Evans T W; Barnes P J
Characterization and distribution of P2-purinoceptor subtypes in rat pulmonary vessels.
The Journal of pharmacology and experimental therapeutics 1989;251(3):1204-10.
-
1989: Stretton C D; Belvisi M G; Barnes P J
Neuropeptide Y modulates non-adrenergic, non-cholinergic neural bronchoconstriction in vivo and in vitro.
British journal of pharmacology 1989;98 Suppl():781P.
-
1989: Stretton C D; Belvisi M G; Barnes P J
The effect of sensory nerve depletion on cholinergic neurotransmission in guinea-pig airways.
British journal of pharmacology 1989;98 Suppl():782P.
-
1989: Nichol G M; Nix A; Chung K F; Barnes P J
Characterisation of bronchoconstrictor responses to sodium metabisulphite aerosol in atopic subjects with and without asthma.
Thorax 1989;44(12):1009-14.
-
1989: Rogers D F; Aursudkij B; Barnes P J
Effects of tachykinins on mucus secretion in human bronchi in vitro.
European journal of pharmacology 1989;174(2-3):283-6.
-
1989: Ichinose M; Barnes P J
Histamine H3-receptors modulate nonadrenergic noncholinergic neural bronchoconstriction in guinea-pig in vivo.
European journal of pharmacology 1989;174(1):49-55.
-
1989: Rhoden K J; Barnes P J
Epithelial modulation of non-adrenergic, non-cholinergic and vasoactive intestinal peptide-induced responses: role of neutral endopeptidase.
European journal of pharmacology 1989;171(2-3):247-50.
-
1989: Liu S F; McCormack D G; Evans T W; Barnes P J
Evidence for two P2-purinoceptor subtypes in human small pulmonary arteries.
British journal of pharmacology 1989;98(3):1014-20.
-
1989: Barnes P J
A new approach to the treatment of asthma.
The New England journal of medicine 1989;321(22):1517-27.
-
1989: McCormack D G; Barnes P J; Evans T W
Purinoceptors in the pulmonary circulation of the rat and their role in hypoxic vasoconstriction.
British journal of pharmacology 1989;98(2):367-72.
-
1989: Dent G; Ukena D; Sybrecht G W; Barnes P J
[3H]WEB 2086 labels platelet activating factor receptors in guinea pig and human lung.
European journal of pharmacology 1989;169(2-3):313-6.
-
1989: Yukawa T; Kroegel C; Evans P; Fukuda T; Chung K F; Barnes P J
Density heterogeneity of eosinophil leucocytes: induction of hypodense eosinophils by platelet-activating factor.
Immunology 1989;68(1):140-3.
-
1989: Chung K F; Cuss F M; Barnes P J
Platelet activating factor: effects on bronchomotor tone and bronchial responsiveness in human beings.
Allergy proceedings : the official journal of regional and state allergy societies 1989;10(5):333-7.
-
1989: Chung K F; Lammers J W; McCusker M; Roberts N M; Nichol G M; Barnes P J
Effect of theophylline on airway responses to inhaled platelet-activating factor in man.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1989;2(8):763-8.
-
1989: McCormack D G; Mak J C; Coupe M O; Barnes P J
Calcitonin gene-related peptide vasodilation of human pulmonary vessels.
Journal of applied physiology (Bethesda, Md. : 1985) 1989;67(3):1265-70.
-
1989: Rhoden K J; Barnes P J
Effect of hydrogen peroxide on guinea-pig tracheal smooth muscle in vitro: role of cyclo-oxygenase and airway epithelium.
British journal of pharmacology 1989;98(1):325-30.
-
1989: Barnes P J
Airway receptors.
Postgraduate medical journal 1989;65(766):532-42.
-
1989: Yukawa T; Kroegel C; Chanez P; Dent G; Ukena D; Chung K F; Barnes P J
Effect of theophylline and adenosine on eosinophil function.
The American review of respiratory disease 1989;140(2):327-33.
-
1989: Lammers J W; Minette P; McCusker M T; Chung K F; Barnes P J
Capsaicin-induced bronchodilation in mild asthmatic subjects: possible role of nonadrenergic inhibitory system.
Journal of applied physiology (Bethesda, Md. : 1985) 1989;67(2):856-61.
-
1989: Belvisi M G; Ichinose M; Barnes P J
Modulation of non-adrenergic, non-cholinergic neural bronchoconstriction in guinea-pig airways via GABAB-receptors.
British journal of pharmacology 1989;97(4):1225-31.
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1989: Stretton C D; Barnes P J
Cholecystokinin-octapeptide constricts guinea-pig and human airways.
British journal of pharmacology 1989;97(3):675-82.
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1989: Rogers D F; Boschetto P; Barnes P J
Plasma exudation. Correlation between Evans blue dye and radiolabeled albumin in guinea pig airways in vivo.
Journal of pharmacological methods 1989;21(4):309-15.
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1989: Kroegel C; Yukawa T; Westwick J; Barnes P J
Evidence for two platelet activating factor receptors on eosinophils: dissociation between PAF-induced intracellular calcium mobilization degranulation and superoxides anion generation in eosinophils.
Biochemical and biophysical research communications 1989;162(1):511-21.
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1989: Barnes P J
New concepts in the pathogenesis of bronchial hyperresponsiveness and asthma.
The Journal of allergy and clinical immunology 1989;83(6):1013-26.
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1989: Ind P W; Dixon C M; Fuller R W; Barnes P J
Anticholinergic blockade of beta-blocker-induced bronchoconstriction.
The American review of respiratory disease 1989;139(6):1390-4.
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1989: Black P N; Fuller R W; Taylor G W; Barnes P J; Dollery C T
Effect of inhaled leukotriene B4 alone and in combination with prostaglandin D2 on bronchial responsiveness to histamine in normal subjects.
Thorax 1989;44(6):491-5.
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1989: Dixon C M; Barnes P J
Bradykinin-induced bronchoconstriction: inhibition by nedocromil sodium and sodium cromoglycate.
British journal of clinical pharmacology 1989;27(6):831-6.
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1989: Kioumis I; Ukena D; Barnes P J
Effect of nedocromil sodium on down-regulation of pulmonary beta-adrenoceptors.
Clinical science (London, England : 1979) 1989;76(6):599-602.
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1989: McCusker M T; Chung K F; Roberts N M; Barnes P J
Effect of topical capsaicin on the cutaneous responses to inflammatory mediators and to antigen in man.
The Journal of allergy and clinical immunology 1989;83(6):1118-24.
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1989: Mak J C; Barnes P J
Muscarinic receptor subtypes in human and guinea pig lung.
European journal of pharmacology 1989;164(2):223-30.
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1989: Evans T W; Rogers D F; Aursudkij B; Chung K F; Barnes P J
Regional and time-dependent effects of inflammatory mediators on airway microvascular permeability in the guinea pig.
Clinical science (London, England : 1979) 1989;76(5):479-85.
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1989: Barnes P J
Our changing understanding of asthma.
Respiratory medicine 1989;83 Suppl A():17-22; discussion 22-3.
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1989: Ukena D; Krogel C; Dent G; Yukawa T; Sybrecht G; Barnes P J
PAF-receptors on eosinophils: identification with a novel ligand, [3H]WEB 2086.
Biochemical pharmacology 1989;38(10):1702-5.
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1989: Ichinose M; Stretton C D; Schwartz J C; Barnes P J
Histamine H3-receptors inhibit cholinergic neurotransmission in guinea-pig airways.
British journal of pharmacology 1989;97(1):13-5.
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1989: Kroegel C; Yukawa T; Dent G; Venge P; Chung K F; Barnes P J
Stimulation of degranulation from human eosinophils by platelet-activating factor.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(10):3518-26.
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1989: Ichinose M; Barnes P J
Inhibitory histamine H3-receptors on cholinergic nerves in human airways.
European journal of pharmacology 1989;163(2-3):383-6.
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1989: Rogers D F; Barnes P J
Opioid inhibition of neurally mediated mucus secretion in human bronchi.
Lancet 1989;1(8644):930-2.
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1989: Barnes P J
Muscarinic receptor subtypes: implications for lung disease.
Thorax 1989;44(3):161-7.
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1989: Chung K F; Barnes P J
Effects of platelet activating factor on airway calibre, airway responsiveness, and circulating cells in asthmatic subjects.
Thorax 1989;44(2):108-15.
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1989: Chung K F; Dent G; Barnes P J
Effects of salbutamol on bronchoconstriction, bronchial hyperresponsiveness, and leucocyte responses induced by platelet activating factor in man.
Thorax 1989;44(2):102-7.
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1989: Boschetto P; Roberts N M; Rogers D F; Barnes P J
Effect of antiasthma drugs on microvascular leakage in guinea pig airways.
The American review of respiratory disease 1989;139(2):416-21.
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1989: Lammers J W; Minette P; McCusker M; Barnes P J
The role of pirenzepine-sensitive (M1) muscarinic receptors in vagally mediated bronchoconstriction in humans.
The American review of respiratory disease 1989;139(2):446-9.
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1989: Kroegel C; Pleass R; Yukawa T; Chung K F; Westwick J; Barnes P J
Characterization of platelet-activating factor-induced elevation of cytosolic free calcium concentration in eosinophils.
FEBS letters 1989;243(1):41-6.
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1989: McCormack D G; Clarke B; Barnes P J
Characterization of adenosine receptors in human pulmonary arteries.
The American journal of physiology 1989;256(1 Pt 2):H41-6.
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1989: Belvisi M G; Rogers D F; Barnes P J
Neurogenic plasma extravasation: inhibition by morphine in guinea pig airways in vivo.
Journal of applied physiology (Bethesda, Md. : 1985) 1989;66(1):268-72.
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1989: Frossard N; Rhoden K J; Barnes P J
Influence of epithelium on guinea pig airway responses to tachykinins: role of endopeptidase and cyclooxygenase.
The Journal of pharmacology and experimental therapeutics 1989;248(1):292-8.
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1989: Barnes P J
Effects of nedocromil sodium on airway microvascular leakage and neural reflexes.
Drugs 1989;37 Suppl 1():94-100; discussion 127-36.
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1989: McCormack D G; Salonen R O; Barnes P J
Effect of sensory neuropeptides on canine bronchial and pulmonary vessels in vitro.
Life sciences 1989;45(25):2405-12.
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1988: McCormack D G; Mak J C; Minette P; Barnes P J
Muscarinic receptor subtypes mediating vasodilation in the pulmonary artery.
European journal of pharmacology 1988;158(3):293-7.
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1988: Rogers D F; Belvisi M G; Aursudkij B; Evans T W; Barnes P J
Effects and interactions of sensory neuropeptides on airway microvascular leakage in guinea-pigs.
British journal of pharmacology 1988;95(4):1109-16.
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1988: Belvisi M G; Chung K F; Jackson D M; Barnes P J
Opioid modulation of non-cholinergic neural bronchoconstriction in guinea-pig in vivo.
British journal of pharmacology 1988;95(2):413-8.
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1988: Kioumis I; Lammers J W; Dent G; Chung K F; Barnes P J
Effect of inhaled platelet-activating factor on circulating neutrophils and platelets in vivo and ex vivo in man.
Prostaglandins 1988;36(3):343-54.
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1988: Mak J C; Barnes P J
Autoradiographic localization of calcitonin gene-related peptide (CGRP) binding sites in human and guinea pig lung.
Peptides 1988;9(5):957-63.
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1988: Beynon H L; Garbett N D; Barnes P J
Severe premenstrual exacerbations of asthma: effect of intramuscular progesterone.
Lancet 1988;2(8607):370-2.
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1988: Evans T W; Rogers D F; Aursudkij B; Chung K F; Barnes P J
Inflammatory mediators involved in antigen-induced airway microvascular leakage in guinea pigs.
The American review of respiratory disease 1988;138(2):395-9.
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1988: Rhoden K J; Meldrum L A; Barnes P J
Inhibition of cholinergic neurotransmission in human airways by beta 2-adrenoceptors.
Journal of applied physiology (Bethesda, Md. : 1985) 1988;65(2):700-5.
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1988: Kroegel C; Yukawa T; Dent G; Chanez P; Chung K F; Barnes P J
Platelet-activating factor induces eosinophil peroxidase release from purified human eosinophils.
Immunology 1988;64(3):559-61.
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1988: Roberts N M; McCusker M; Chung K F; Barnes P J
Effect of a PAF antagonist, BN52063, on PAF-induced bronchoconstriction in normal subjects.
British journal of clinical pharmacology 1988;26(1):65-72.
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1988: Minette P A; Barnes P J
Prejunctional inhibitory muscarinic receptors on cholinergic nerves in human and guinea pig airways.
Journal of applied physiology (Bethesda, Md. : 1985) 1988;64(6):2532-7.
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1988: Chung K F; Minette P; McCusker M; Barnes P J
Ketotifen inhibits the cutaneous but not the airway responses to platelet-activating factor in man.
The Journal of allergy and clinical immunology 1988;81(6):1192-8.
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1988: Robertson D N; Coyle A J; Rhoden K J; Grandordy B; Page C P; Barnes P J
The effect of platelet-activating factor on histamine and muscarinic receptor function in guinea pig airways.
The American review of respiratory disease 1988;137(6):1317-22.
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1988: Evans T W; Dent G; Rogers D F; Aursudkij B; Chung K F; Barnes P J
Effect of a Paf antagonist, WEB 2086, on airway microvascular leakage in the guinea-pig and platelet aggregation in man.
British journal of pharmacology 1988;94(1):164-8.
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1988: Barnes P J; Chung K F; Page C P
Platelet-activating factor as a mediator of allergic disease.
The Journal of allergy and clinical immunology 1988;81(5 Pt 1):919-34.
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1988: Lammers J W; Minette P; McCusker M T; Chung K F; Barnes P J
Nonadrenergic bronchodilator mechanisms in normal human subjects in vivo.
Journal of applied physiology (Bethesda, Md. : 1985) 1988;64(5):1817-22.
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1988: Grandordy B M; Frossard N; Rhoden K J; Barnes P J
Tachykinin-induced phosphoinositide breakdown in airway smooth muscle and epithelium: relationship to contraction.
Molecular pharmacology 1988;33(5):515-9.
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1988: Carstairs J R; Norman P; Abram T S; Barnes P J
Autoradiographic localization of leukotriene C4 and D4 binding sites in guinea-pig lung.
Prostaglandins 1988;35(4):503-13.
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1988: Stretton C D; Barnes P J
Modulation of cholinergic neurotransmission in guinea-pig trachea by neuropeptide Y.
British journal of pharmacology 1988;93(3):672-8.
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1988: Ukena D; Dent G; Birke F W; Robaut C; Sybrecht G W; Barnes P J
Radioligand binding of antagonists of platelet-activating factor to intact human platelets.
FEBS letters 1988;228(2):285-9.
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1988: Chung K F; Barnes P J
PAF antagonists. Their potential therapeutic role in asthma.
Drugs 1988;35(2):93-103.
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1988: Evans T W; Dixon C M; Clarke B; Conradson T B; Barnes P J
Comparison of neurokinin A and substance P on cardiovascular and airway function in man.
British journal of clinical pharmacology 1988;25(2):273-5.
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1988: Barnes P J
Platelet-activating factor and asthma.
The Journal of allergy and clinical immunology 1988;81(1):152-60.
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1988: Chung K F; Barnes P J
Respiratory and allergic disease. II. Chronic obstructive airways disease and respiratory infections.
British medical journal (Clinical research ed.) 1988;296(6615):111-5.
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1988: Chung K F; Barnes P J
Respiratory and allergic disease. I.
British medical journal (Clinical research ed.) 1988;296(6614):29-33.
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1988: Clarke B; Conradson T B; Dixon C M; Barnes P J
Reproducibility of heart rate changes following adenosine infusion in man.
European journal of clinical pharmacology 1988;35(3):309-11.
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1988: Coupe M O; Clarke B; Robson A; Oldershaw P J; Barnes P J
The cardiovascular effects of nebulized adenosine in man.
European journal of clinical pharmacology 1988;34(6):645-7.
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1988: Barnes P J
Nocturnal asthma.
Postgraduate medical journal 1988;64 Suppl 4():68-73.
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1988: Barnes P J
The drug therapy of asthma: directions for the 21st century.
Agents and actions. Supplements 1988;23():293-313.
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1988: Barnes P J
Neuropeptides in human airways.
Progress in clinical and biological research 1988;263():111-21.
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1988: Barnes P J
Neuropeptides and airway smooth muscle.
Pharmacology & therapeutics 1988;36(1):119-29.
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1987: Conradson T B; Clarke B; Dixon C M; Dalton R N; Barnes P J
Effects of adenosine on autonomic control of heart rate in man.
Acta physiologica Scandinavica 1987;131(4):525-31.
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1987: Fuller R W; Conradson T B; Dixon C M; Crossman D C; Barnes P J
Sensory neuropeptide effects in human skin.
British journal of pharmacology 1987;92(4):781-8.
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1987: Barnes P J
Neuropeptides in human airways: function and clinical implications.
The American review of respiratory disease 1987;136(6 Pt 2):S77-83.
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1987: Maxwell D L; Fuller R W; Conradson T B; Dixon C M; Aber V; Hughes J M; Barnes P J
Contrasting effects of two xanthines, theophylline and enprofylline, on the cardio-respiratory stimulation of infused adenosine in man.
Acta physiologica Scandinavica 1987;131(3):459-65.
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1987: Wilson N M; Green S; Coe C; Barnes P J
Duration of protection by oxitropium bromide against cholinergic challenge.
European journal of respiratory diseases 1987;71(5):455-8.
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1987: Barnes P J
Cholinergic control of airway smooth muscle.
The American review of respiratory disease 1987;136(4 Pt 2):S42-5.
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1987: Cuss F M; Barnes P J
Airway smooth muscle and disease workshop: epithelial mediators.
The American review of respiratory disease 1987;136(4 Pt 2):S32-5.
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1987: Grandordy B M; Barnes P J
Airway smooth muscle and disease workshop: phosphoinositide turnover.
The American review of respiratory disease 1987;136(4 Pt 2):S17-20.
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1987: Palmer J B; Barnes P J
Neuropeptides and airway smooth muscle function.
The American review of respiratory disease 1987;136(4 Pt 2):S50-4.
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1987: Fuller R W; Maxwell D L; Conradson T B; Dixon C M; Barnes P J
Circulatory and respiratory effects of infused adenosine in conscious man.
British journal of clinical pharmacology 1987;24(3):309-17.
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1987: Frossard N; Barnes P J
Mu-opioid receptors modulate non-cholinergic constrictor nerves in guinea-pig airways.
European journal of pharmacology 1987;141(3):519-22.
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1987: Evans T W; Chung K F; Rogers D F; Barnes P J
Effect of platelet-activating factor on airway vascular permeability: possible mechanisms.
Journal of applied physiology (Bethesda, Md. : 1985) 1987;63(2):479-84.
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1987: Dixon C M; Fuller R W; Barnes P J
Effect of nedocromil sodium on sulphur dioxide induced bronchoconstriction.
Thorax 1987;42(6):462-5.
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1987: Barnes P J
The changing face of asthma.
The Quarterly journal of medicine 1987;63(241):359-65.
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1987: Barnes P J; Grandordy B M; Page C P; Rhoden K J; Robertson D N
The effect of platelet activating factor on pulmonary beta-adrenoceptors.
British journal of pharmacology 1987;90(4):709-15.
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1987: Conradson T B; Dixon C M; Clarke B; Barnes P J
Cardiovascular effects of infused adenosine in man: potentiation by dipyridamole.
Acta physiologica Scandinavica 1987;129(3):387-91.
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1987: Fuller R W; Dixon C M; Cuss F M; Barnes P J
Bradykinin-induced bronchoconstriction in humans. Mode of action.
The American review of respiratory disease 1987;135(1):176-80.
-
1987: Barnes P J
Muscarinic receptors in lung.
Postgraduate medical journal 1987;63 Suppl 1():13-9.
-
1987: Barnes P J
New concepts in the pathogenesis of bronchial hyperresponsiveness.
Agents and actions. Supplements 1987;21():225-37.
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1987: Norman P; Carstairs J A; Abram T S; Barnes P J
Differential autoradiographic localization of leukotriene binding sites in guinea pig airways.
Advances in prostaglandin, thromboxane, and leukotriene research 1987;17A():505-7.
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1986: Cuss F M; Dixon C M; Barnes P J
Effects of inhaled platelet activating factor on pulmonary function and bronchial responsiveness in man.
Lancet 1986;2(8500):189-92.
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