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Rob Liskamp
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43
Rijkers, Dirk
26
Kruijtzer, John
23
Pieters, Roland
10
de Mol, Nico
10
Kemmink, Johan
9
Elgersma, Ronald
8
Killian, Antoinette
8
de Kruijff, Ben
8
Brouwer, Arwin
7
Boerman, Otto
7
Branderhorst, Hilbert
7
Dekker, Frank
7
Hilbers, Hans
7
Fischer, Marcel
7
heck, albert
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All Publications
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2009: Elgersma Ronald C; van Dijk Maarten; Dechesne Annemarie C; van Nostrum Cornelus F; Hennink Wim E; Rijkers Dirk T S; Liskamp Rob M J
Microwave-assisted click polymerization for the synthesis of Abeta(16-22) cyclic oligomers and their self-assembly into polymorphous aggregates.
Organic & biomolecular chemistry 2009;7(21):4517-25.
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2009: Kuil Joeri; Branderhorst Hilbert M; Pieters Roland J; de Mol Nico J; Liskamp Rob M J
ITAM-derived phosphopeptide-containing dendrimers as multivalent ligands for Syk tandem SH2 domain.
Organic & biomolecular chemistry 2009;7(19):4088-94.
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2009: Kuil Joeri; van Wandelen Loek T M; de Mol Nico J; Liskamp Rob M J
Switching between low and high affinity for the Syk tandem SH2 domain by irradiation of azobenzene containing ITAM peptidomimetics.
Journal of peptide science : an official publication of the European Peptide Society 2009;15(10):685-91.
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2009: Poot Alex J; van Ameijde Jeroen; Slijper Monique; van den Berg Adriënne; Hilhorst Riet; Ruijtenbeek Rob; Rijkers Dirk T S; Liskamp Rob M J
Development of selective bisubstrate-based inhibitors against protein kinase C (PKC) isozymes by using dynamic peptide microarrays.
Chembiochem : a European journal of chemical biology 2009;10(12):2042-51.
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2009: Nuijens Timo; Cusan Claudia; Kruijtzer John A W; Rijkers Dirk T S; Liskamp Rob M J; Quaedflieg Peter J L M
Enzymatic synthesis of C-terminal arylamides of amino acids and peptides.
The Journal of organic chemistry 2009;74(15):5145-50.
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2009: Yim Cheng-Bin; Boerman Otto C; de Visser Monique; de Jong Marion; Dechesne Annemarie C; Rijkers Dirk T S; Liskamp Rob M J
Versatile conjugation of octreotide to dendrimers by cycloaddition ("click") chemistry to yield high-affinity multivalent cyclic Peptide dendrimers.
Bioconjugate chemistry 2009;20(7):1323-31.
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2009: Bauke Albada H; Arnusch Christopher J; Branderhorst Hilbert M; Verel Anne-Marie; Janssen Wouter T M; Breukink Eefjan; de Kruijff Ben; Pieters Roland J; Liskamp Rob M J
Potential scorpionate antibiotics: targeted hydrolysis of lipid II containing model membranes by vancomycin-TACzyme conjugates and modulation of their antibacterial activity by Zn-ions.
Bioorganic & medicinal chemistry letters 2009;19(14):3721-4.
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2009: van Scherpenzeel Monique; Moret Ed E; Ballell Lluis; Liskamp Rob M J; Nilsson Ulf J; Leffler Hakon; Pieters Roland J
Synthesis and evaluation of new thiodigalactoside-based chemical probes to label galectin-3.
Chembiochem : a European journal of chemical biology 2009;10(10):1724-33.
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2009: Bunschoten Anton; Kruijtzer John A W; Ippel Johannes H; de Haas Carla J C; van Strijp Jos A G; Kemmink Johan; Liskamp Rob M J
A general sequence independent solid phase method for the site specific synthesis of multiple sulfated-tyrosine containing peptides.
Chemical communications (Cambridge, England) 2009;(21):2999-3001.
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2009: Ippel Johannes H; de Haas Carla J C; Bunschoten Anton; van Strijp Jos A G; Kruijtzer John A W; Liskamp Rob M J; Kemmink Johan
Structure of the tyrosine-sulfated C5a receptor N terminus in complex with chemotaxis inhibitory protein of Staphylococcus aureus.
The Journal of biological chemistry 2009;284(18):12363-72.
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2009: Teertstra Wieke R; van der Velden Gisela J; de Jong Jan F; Kruijtzer John A W; Liskamp Rob M J; Kroon-Batenburg Loes M J; Müller Wally H; Gebbink Martijn F B G; Wösten Han A B
The filament-specific Rep1-1 repellent of the phytopathogen Ustilago maydis forms functional surface-active amyloid-like fibrils.
The Journal of biological chemistry 2009;284(14):9153-9.
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2009: Chamorro Cristina; Kruijtzer John A W; Farsaraki Marina; Balzarini Jan; Liskamp Rob M J
A general approach for the non-stop solid phase synthesis of TAC-scaffolded loops towards protein mimics containing discontinuous epitopes.
Chemical communications (Cambridge, England) 2009;(7):821-3.
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2009: Gubbens Jacob; Ruijter Eelco; de Fays Laurence E V; Damen J Mirjam A; de Kruijff Ben; Slijper Monique; Rijkers Dirk T S; Liskamp Rob M J; de Kroon Anton I P M
Photocrosslinking and click chemistry enable the specific detection of proteins interacting with phospholipids at the membrane interface.
Chemistry & biology 2009;16(1):3-14.
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2009: Harmsen Rianne A G; Ghalit Nourdin; Kemmink Johan; Hilbers Hans W; Breukink Eefjan; Rijkers Dirk T S; Liskamp Rob M J
Alkene/alkane-bridged mimics of the lantibiotic nisin: toward novel peptide-based antibiotics.
Advances in experimental medicine and biology 2009;611():533-4.
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2009: Elgersma Ronald C; Rijkers Dirk T S; Liskamp Rob M J
pH controlled aggregation morphology of Abeta(16-22): formation of peptide nanotubes, helical tapes and amyloid fibrils.
Advances in experimental medicine and biology 2009;611():239-40.
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2009: Kuil Joeri; van Wandelen Loek T M; de Mol Nico J; Liskamp Rob M J
Peptidomimetic ligands for the tandem SH2 domain of the Syk protein involved in signal transduction.
Advances in experimental medicine and biology 2009;611():81-2.
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2008: Arnusch Christopher J; Bonvin Alexandre M J J; Verel Anne Marie; Jansen Wouter T M; Liskamp Rob M J; de Kruijff Ben; Pieters Roland J; Breukink Eefjan
The vancomycin-nisin(1-12) hybrid restores activity against vancomycin resistant Enterococci.
Biochemistry 2008;47(48):12661-3.
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2008: Albada H Bauke; Liskamp Rob M J
TAC-scaffolded tripeptides as artificial hydrolytic receptors: a combinatorial approach toward esterase mimics.
Journal of combinatorial chemistry 2008;10(6):814-24.
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2008: van Dijk Maarten; Nollet Maria L; Weijers Pascal; Dechesne Annemarie C; van Nostrum Cornelus F; Hennink Wim E; Rijkers Dirk T S; Liskamp Rob M J
Synthesis and characterization of biodegradable peptide-based polymers prepared by microwave-assisted click chemistry.
Biomacromolecules 2008;9(10):2834-43.
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2008: Martin Nathaniel I; Liskamp Rob M J
Preparation of N(G)-substituted L-arginine analogues suitable for solid phase peptide synthesis.
The Journal of organic chemistry 2008;73(19):7849-51.
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2008: van Ingen Hugo; van Schaik Frederik M A; Wienk Hans; Ballering Joost; Rehmann Holger; Dechesne Annemarie C; Kruijzer John A W; Liskamp Rob M J; Timmers H Th Marc; Boelens Rolf
Structural insight into the recognition of the H3K4me3 mark by the TFIID subunit TAF3.
Structure (London, England : 1993) 2008;16(8):1245-56.
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2008: Branderhorst Hilbert M; Ruijtenbeek Rob; Liskamp Rob M J; Pieters Roland J
Multivalent carbohydrate recognition on a glycodendrimer-functionalized flow-through chip.
Chembiochem : a European journal of chemical biology 2008;9(11):1836-44.
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2008: Branderhorst Hilbert M; Kooij Raymond; Salminen Annika; Jongeneel Lieneke H; Arnusch Christopher J; Liskamp Rob M J; Finne Jukka; Pieters Roland J
Synthesis of multivalent Streptococcus suis adhesion inhibitors by enzymatic cleavage of polygalacturonic acid and 'click' conjugation.
Organic & biomolecular chemistry 2008;6(8):1425-34.
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2008: Kuil Joeri; van Wandelen Loek T M; de Mol Nico J; Liskamp Rob M J
A photoswitchable ITAM peptidomimetic: synthesis and real time surface plasmon resonance (SPR) analysis of the effects of cis-trans isomerization on binding.
Bioorganic & medicinal chemistry 2008;16(3):1393-9.
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2008: Ozdirekcan Suat; Nyholm Thomas K M; Raja Mobeen; Rijkers Dirk T S; Liskamp Rob M J; Killian J Antoinette
Influence of trifluoroethanol on membrane interfacial anchoring interactions of transmembrane alpha-helical peptides.
Biophysical journal 2008;94(4):1315-25.
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2008: Brouwer Arwin J; Elgersma Ronald C; Jagodzinska Monika; Rijkers Dirk T S; Liskamp Rob M J
Delayed fibril formation of amylin(20-29) by incorporation of alkene dipeptidosulfonamide isosteres obtained by solid phase olefin cross metathesis.
Bioorganic & medicinal chemistry letters 2008;18(1):78-84.
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2007: Albada H Bauke; Soulimani Fouad; Weckhuysen Bert M; Liskamp Rob M J
Scaffolded amino acids as a close structural mimic of type-3 copper binding sites.
Chemical communications (Cambridge, England) 2007;(46):4895-7.
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2007: Branderhorst Hilbert M; Liskamp Rob M J; Visser Gerben M; Pieters Roland J
Strong inhibition of cholera toxin binding by galactose dendrimers.
Chemical communications (Cambridge, England) 2007;(47):5043-5.
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2007: Arnusch Christopher J; Branderhorst Hilbert; de Kruijff Ben; Liskamp Rob M J; Breukink Eefjan; Pieters Roland J
Enhanced membrane pore formation by multimeric/oligomeric antimicrobial peptides.
Biochemistry 2007;46(46):13437-42.
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2007: Elgersma Ronald C; Posthuma George; Rijkers Dirk T S; Liskamp Rob M J
Backbone-modified amylin derivatives: implications for amyloid inhibitor design and as template for self-assembling bionanomaterials.
Journal of peptide science : an official publication of the European Peptide Society 2007;13(11):709-16.
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2007: van Zoelen Dirk-Jan; Egmond Maarten R; Pieters Roland J; Liskamp Rob M J
Synthesis and evaluation of TAC-based inhibitors of papain as mimics of cystatin B.
Chembiochem : a European journal of chemical biology 2007;8(16):1950-6.
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2007: Brouwer Arwin J; Bunschoten Anton; Liskamp Rob M J
Synthesis and evaluation of chloromethyl sulfoxides as a new class of selective irreversible cysteine protease inhibitors.
Bioorganic & medicinal chemistry 2007;15(22):6985-93.
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2007: Hijnen Marcel; van Zoelen Dirk J; Chamorro Cristina; van Gageldonk Pieter; Mooi Frits R; Berbers Guy; Liskamp Rob M J
A novel strategy to mimic discontinuous protective epitopes using a synthetic scaffold.
Vaccine 2007;25(37-38):6807-17.
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2007: Ghalit Nourdin; Reichwein John F; Hilbers Hans W; Breukink Eefjan; Rijkers Dirk T S; Liskamp Rob M J
Synthesis of bicyclic alkene-/alkane-bridged nisin mimics by ring-closing metathesis and their biochemical evaluation as lipid II binders: toward the design of potential novel antibiotics.
Chembiochem : a European journal of chemical biology 2007;8(13):1540-54.
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2007: Pukin Aliaksei V; Branderhorst Hilbert M; Sisu Cristina; Weijers Carel A G M; Gilbert Michel; Liskamp Rob M J; Visser Gerben M; Zuilhof Han; Pieters Roland J
Strong inhibition of cholera toxin by multivalent GM1 derivatives.
Chembiochem : a European journal of chemical biology 2007;8(13):1500-3.
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2007: Merkx Remco; van Haren Matthijs J; Rijkers Dirk T S; Liskamp Rob M J
Resin-bound sulfonyl azides: efficient loading and activation strategy for the preparation of the N-acyl sulfonamide linker.
The Journal of organic chemistry 2007;72(12):4574-7.
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2007: de Planque Maurits R R; Raussens Vincent; Contera Sonia Antoranz; Rijkers Dirk T S; Liskamp Rob M J; Ruysschaert Jean-Marie; Ryan John F; Separovic Frances; Watts Anthony
beta-Sheet structured beta-amyloid(1-40) perturbs phosphatidylcholine model membranes.
Journal of molecular biology 2007;368(4):982-97.
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2007: Elgersma Ronald C; Mulder Gwenn E; Kruijtzer John A W; Posthuma George; Rijkers Dirk T S; Liskamp Rob M J
Transformation of the amyloidogenic peptide amylin(20-29) into its corresponding peptoid and retropeptoid: access to both an amyloid inhibitor and template for self-assembled supramolecular tapes.
Bioorganic & medicinal chemistry letters 2007;17(7):1837-42.
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2007: Dijkgraaf Ingrid; Rijnders Anneloes Y; Soede Annemieke; Dechesne Annemarie C; van Esse G Wilma; Brouwer Arwin J; Corstens Frans H M; Boerman Otto C; Rijkers Dirk T S; Liskamp Rob M J
Synthesis of DOTA-conjugated multivalent cyclic-RGD peptide dendrimers via 1,3-dipolar cycloaddition and their biological evaluation: implications for tumor targeting and tumor imaging purposes.
Organic & biomolecular chemistry 2007;5(6):935-44.
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2007: Ghalit Nourdin; Kemmink Johan; Hilbers Hans W; Versluis Cees; Rijkers Dirk T S; Liskamp Rob M J
Step-wise and pre-organization induced synthesis of a crossed alkene-bridged nisin Z DE-ring mimic by ring-closing metathesis.
Organic & biomolecular chemistry 2007;5(6):924-34.
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2007: Dijk Maarten van; Mustafa Khalid; Dechesne Annemarie C; Nostrum Cornelus F van; Hennink Wim E; Rijkers Dirk T S; Liskamp Rob M J
Synthesis of peptide-based polymers by microwave-assisted cycloaddition backbone polymerization.
Biomacromolecules 2007;8(2):327-30.
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2007: Dijkgraaf Ingrid; Kruijtzer John A W; Frielink Cathelijne; Corstens Frans H M; Oyen Wim J G; Liskamp Rob M J; Boerman Otto C
Alpha v beta 3 integrin-targeting of intraperitoneally growing tumors with a radiolabeled RGD peptide.
International journal of cancer. Journal international du cancer 2007;120(3):605-10.
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2007: Dijkgraaf Ingrid; Kruijtzer John A W; Liu Shuang; Soede Annemieke C; Oyen Wim J G; Corstens Frans H M; Liskamp Rob M J; Boerman Otto C
Improved targeting of the alpha(v)beta (3) integrin by multimerisation of RGD peptides.
European journal of nuclear medicine and molecular imaging 2007;34(2):267-73.
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2007: Dijkgraaf Ingrid; Liu Shuang; Kruijtzer John A W; Soede Annemieke C; Oyen Wim J G; Liskamp Rob M J; Corstens Frans H M; Boerman Otto C
Effects of linker variation on the in vitro and in vivo characteristics of an 111In-labeled RGD peptide.
Nuclear medicine and biology 2007;34(1):29-35.
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2007: van Scherpenzeel Monique; van der Pot Martin; Arnusch Christopher J; Liskamp Rob M J; Pieters Roland J
Detection of galectin-3 by novel peptidic photoprobes.
Bioorganic & medicinal chemistry letters 2007;17(2):376-8.
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2006: Poot Alex J; Ruijter Eelco; Nuijens Timo; Dirksen Eef H C; Heck Albert J R; Slijper Monique; Rijkers Dirk T S; Liskamp Rob M J
Selective enrichment of Ser-/Thr-phosphorylated peptides in the presence of Ser-/Thr-glycosylated peptides.
Proteomics 2006;6(24):6394-9.
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2006: Ballell Lluis; van Scherpenzeel Monique; Buchalova Katerina; Liskamp Rob M J; Pieters Roland J
A new chemical probe for the detection of the cancer-linked galectin-3.
Organic & biomolecular chemistry 2006;4(23):4387-94.
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2006: Dijkgraaf Ingrid; Kruijtzer John A W; Frielink Cathelijne; Soede Annemieke C; Hilbers Hans W; Oyen Wim J G; Corstens Frans H M; Liskamp Rob M J; Boerman Otto C
Synthesis and biological evaluation of potent alphavbeta3-integrin receptor antagonists.
Nuclear medicine and biology 2006;33(8):953-61.
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2006: Elgersma Ronald C; Meijneke Tania; de Jong Remco; Brouwer Arwin J; Posthuma George; Rijkers Dirk T S; Liskamp Rob M J
Synthesis and structural investigations of N-alkylated beta-peptidosulfonamide-peptide hybrids of the amyloidogenic amylin(20-29) sequence: Implications of supramolecular folding for the design of peptide-based bionanomaterials.
Organic & biomolecular chemistry 2006;4(19):3587-97.
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2006: Dirksen Eef H C; Pinkse Martijn W H; Rijkers Dirk T S; Cloos Jacqueline; Liskamp Rob M J; Slijper Monique; Heck Albert J R
Investigating the dynamic nature of the interactions between nuclear proteins and histones upon DNA damage using an immobilized peptide chemical proteomics approach.
Journal of proteome research 2006;5(9):2380-8.
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2006: Elgersma Ronald C; Meijneke Tania; Posthuma George; Rijkers Dirk T S; Liskamp Rob M J
Self-assembly of amylin(20-29) amide-bond derivatives into helical ribbons and peptide nanotubes rather than fibrils.
Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(14):3714-25.
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2006: ten Brink Hefziba T; Rijkers Dirk T S; Liskamp Rob M J
Synthesis of alkyne-bridged cyclic tripeptides toward constrained mimics of vancomycin.
The Journal of organic chemistry 2006;71(5):1817-24.
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2006: Engel Maarten F M; Yigittop HaciAli; Elgersma Ronald C; Rijkers Dirk T S; Liskamp Rob M J; de Kruijff Ben; Höppener Jo W M; Antoinette Killian J
Islet amyloid polypeptide inserts into phospholipid monolayers as monomer.
Journal of molecular biology 2006;356(3):783-9.
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2006: Kasyanov Vladimir; Isenburg Jason; Draughn Robert A; Hazard Starr; Hodde Jason; Ozolanta Iveta; Murovska Modra; Halkes S Bart; Vrasidas Ioannis; Liskamp Rob M J; Pieters Roland J; Simionescu Dan; Markwald Roger R; Mironov Vladimir
Tannic acid mimicking dendrimers as small intestine submucosa stabilizing nanomordants.
Biomaterials 2006;27(5):745-51.
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2005: van der Veken Pieter; Dirksen Eef H C; Ruijter Eelco; Elgersma Ronald C; Heck Albert J R; Rijkers Dirk T S; Slijper Monique; Liskamp Rob M J
Development of a novel chemical probe for the selective enrichment of phosphorylated serine- and threonine-containing peptides.
Chembiochem : a European journal of chemical biology 2005;6(12):2271-80.
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2005: de Mol Nico J; Catalina M Isabel; Dekker Frank J; Fischer Marcel J E; Heck Albert J R; Liskamp Rob M J
Protein flexibility and ligand rigidity: a thermodynamic and kinetic study of ITAM-based ligand binding to Syk tandem SH2.
Chembiochem : a European journal of chemical biology 2005;6(12):2261-70.
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2005: Haas Pieter-Jan; de Haas Carla J C; Poppelier Miriam J J C; van Kessel Kok P M; van Strijp Jos A G; Dijkstra Klaas; Scheek Ruud M; Fan Hao; Kruijtzer John A W; Liskamp Rob M J; Kemmink Johan
The structure of the C5a receptor-blocking domain of chemotaxis inhibitory protein of Staphylococcus aureus is related to a group of immune evasive molecules.
Journal of molecular biology 2005;353(4):859-72.
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2005: Broekema Matthias; van Eerd Julliëtte J E M; Oyen Wim J G; Corstens Frans H M; Liskamp Rob M J; Boerman Otto C; Harris Thomas D
Synthesis of leukotriene B4 antagonists labeled with In-111 or Tc-99m to image infectious and inflammatory foci.
Journal of medicinal chemistry 2005;48(20):6442-53.
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2005: Autar Reshma; Liskamp Rob M J; Pieters Roland J
A facile synthesis of the GalNAcbeta1-->4Gal target sequence of respiratory pathogens.
Carbohydrate research 2005;340(15):2436-42.
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2005: Rijkers Dirk T S; van Esse G Wilma; Merkx Remco; Brouwer Arwin J; Jacobs Hans J F; Pieters Roland J; Liskamp Rob M J
Efficient microwave-assisted synthesis of multivalent dendrimeric peptides using cycloaddition reaction (click) chemistry.
Chemical communications (Cambridge, England) 2005;(36):4581-3.
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2005: Ghalit Nourdin; Poot Alex J; Fürstner Alois; Rijkers Dirk T S; Liskamp Rob M J
Ring-closing alkyne metathesis approach toward the synthesis of alkyne mimics of thioether A-, B-, C-, and DE-ring systems of the lantibiotic nisin Z.
Organic letters 2005;7(14):2961-4.
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2005: Catalina M Isabel; Fischer Marcel J E; Dekker Frank J; Liskamp Rob M J; Heck Albert J R
Binding of a diphosphorylated-ITAM peptide to spleen tyrosine kinase (Syk) induces distal conformational changes: a hydrogen exchange mass spectrometry study.
Journal of the American Society for Mass Spectrometry 2005;16(7):1039-51.
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2005: Wels Bas; Kruijtzer John A W; Garner Keith; Nijenhuis Wouter A J; Gispen Willem Hendrik; Adan Roger A H; Liskamp Rob M J
Synthesis of a novel potent cyclic peptide MC4-ligand by ring-closing metathesis.
Bioorganic & medicinal chemistry 2005;13(13):4221-7.
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2005: Kruijtzer John A W; Nijenhuis Wouter A J; Wanders Nienke; Gispen Willem Hendrik; Liskamp Rob M J; Adan Roger A H
Peptoid-peptide hybrids as potent novel melanocortin receptor ligands.
Journal of medicinal chemistry 2005;48(13):4224-30.
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2005: Merkx Remco; Brouwer Arwin J; Rijkers Dirk T S; Liskamp Rob M J
Highly efficient coupling of beta-substituted aminoethane sulfonyl azides with thio acids, toward a new chemical ligation reaction.
Organic letters 2005;7(6):1125-8.
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2005: de Mol Nico J; Dekker Frank J; Broutin Isabel; Fischer Marcel J E; Liskamp Rob M J
Surface plasmon resonance thermodynamic and kinetic analysis as a strategic tool in drug design. Distinct ways for phosphopeptides to plug into Src- and Grb2 SH2 domains.
Journal of medicinal chemistry 2005;48(3):753-63.
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2005: de Haan Ellen C; Moret Ed E; Wagenaar-Hilbers Josée P A; Liskamp Rob M J; Wauben Marca H M
Possibilities and limitations in the rational design of modified peptides for T cell mediated immunotherapy.
Molecular immunology 2005;42(3):365-73.
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2005: de Haan Ellen C; Wagenaar-Hilbers Josée P A; Liskamp Rob M J; Moret Ed E; Wauben Marca H M
Limited plasticity in T cell recognition of modified T cell receptor contact residues in MHC class II bound peptides.
Molecular immunology 2005;42(3):355-64.
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2005: Ballell Lluis; Alink Kirstin J; Slijper Monique; Versluis Cees; Liskamp Rob M J; Pieters Roland J
A new chemical probe for proteomics of carbohydrate-binding proteins.
Chembiochem : a European journal of chemical biology 2005;6(2):291-5.
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2005: van Meer Gerrit; Liskamp Rob M J
Brilliant lipids.
Nature methods 2005;2(1):14-5.
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2005: Ghalit Nourdin; Rijkers Dirk T S; Kemmink Johan; Versluis Cees; Liskamp Rob M J
Pre-organization induced synthesis of a crossed alkene-bridged nisin Z DE-ring mimic by ring-closing metathesis.
Chemical communications (Cambridge, England) 2005;(2):192-4.
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2005: Ozdirekcan Suat; Rijkers Dirk T S; Liskamp Rob M J; Killian J Antoinette
Influence of flanking residues on tilt and rotation angles of transmembrane peptides in lipid bilayers. A solid-state 2H NMR study.
Biochemistry 2005;44(3):1004-12.
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2005: Wels Bas; Kruijtzer John A W; Garner Keith M; Adan Roger A H; Liskamp Rob M J
Synthesis of cyclic peptidosulfonamides as scaffolds for MC4 pharmacophoric groups.
Bioorganic & medicinal chemistry letters 2005;15(2):287-90.
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2004: Joosten John A F; Loimaranta Vuokko; Appeldoorn Chantal C M; Haataja Sauli; El Maate Fatna Ait; Liskamp Rob M J; Finne Jukka; Pieters Roland J
Inhibition of Streptococcus suis adhesion by dendritic galabiose compounds at low nanomolar concentration.
Journal of medicinal chemistry 2004;47(26):6499-508.
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2004: Haas Pieter-Jan; de Haas Carla J C; Kleibeuker Wendy; Poppelier Miriam J J G; van Kessel Kok P M; Kruijtzer John A W; Liskamp Rob M J; van Strijp Jos A G
N-terminal residues of the chemotaxis inhibitory protein of Staphylococcus aureus are essential for blocking formylated peptide receptor but not C5a receptor.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(9):5704-11.
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2004: de Planque Maurits R R; Rijkers Dirk T S; Fletcher Jamie I; Liskamp Rob M J; Separovic Frances
The alphaM1 segment of the nicotinic acetylcholine receptor exhibits conformational flexibility in a membrane environment.
Biochimica et biophysica acta 2004;1665(1-2):40-7.
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2004: Rijkers Dirk T S; den Hartog Jack A J; Liskamp Rob M J
Synthesis and biological activity of N-terminal lipidated and/or fluorescently labeled conjugates of astressin as corticotropin releasing factor antagonists.
Bioorganic & medicinal chemistry 2004;12(19):5099-106.
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2004: ten Brink Hefziba T; Rijkers Dirk T S; Kemmink Johan; Hilbers Hans W; Liskamp Rob M J
Ring-closing metathesis for the synthesis of side chain knotted pentapeptides inspired by vancomycin.
Organic & biomolecular chemistry 2004;2(18):2658-63.
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2004: Arosio Daniela; Vrasidas Ioannis; Valentini Paola; Liskamp Rob M J; Pieters Roland J; Bernardi Anna
Synthesis and cholera toxin binding properties of multivalent GM1 mimics.
Organic & biomolecular chemistry 2004;2(14):2113-24.
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2004: Nijenhuis Wouter A J; Wanders Nienke; Kruijtzer John A W; Liskamp Rob M; Gispen Willem Hendrik; Adan Roger A H
Accelerating sensory recovery after sciatic nerve crush: non-selective versus melanocortin MC4 receptor-selective peptides.
European journal of pharmacology 2004;495(2-3):145-52.
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2004: Strandberg Erik; Ozdirekcan Suat; Rijkers Dirk T S; van der Wel Patrick C A; Koeppe Roger E; Liskamp Rob M J; Killian J Antoinette
Tilt angles of transmembrane model peptides in oriented and non-oriented lipid bilayers as determined by 2H solid-state NMR.
Biophysical journal 2004;86(6):3709-21.
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2004: Brouwer Arwin J; Liskamp Rob M J
Synthesis of cyclic peptidosulfonamides by ring-closing metathesis.
The Journal of organic chemistry 2004;69(11):3662-8.
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2004: Ridder Anja N J A; Spelbrink Robin E J; Demmers Jeroen A A; Rijkers Dirk T S; Liskamp Rob M J; Brunner Josef; Heck Albert J R; de Kruijff Ben; Killian J Antoinette
Photo-crosslinking analysis of preferential interactions between a transmembrane peptide and matching lipids.
Biochemistry 2004;43(15):4482-9.
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2004: Rijkers Dirk T S; Kruijtzer John A W; van Oostenbrugge Marja; Ronken Eric; den Hartog Jack A J; Liskamp Rob M J
Structure-activity studies on the corticotropin releasing factor antagonist astressin, leading to a minimal sequence necessary for antagonistic activity.
Chembiochem : a European journal of chemical biology 2004;5(3):340-8.
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2004: De Planque Maurits R R; Rijkers Dirk T S; Liskamp Rob M J; Separovic Frances
The alphaM1 transmembrane segment of the nicotinic acetylcholine receptor interacts strongly with model membranes.
Magnetic resonance in chemistry : MRC 2004;42(2):148-54.
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2004: de Haan Ellen C; Wauben Marca H M; Wagenaar-Hilbers Josée P A; Grosfeld-Stulemeyer Mayken C; Rijkers Dirk T S; Moret Ed E; Liskamp Rob M J
Stabilization of peptide guinea pig myelin basic protein 72-85 by N-terminal acetylation-implications for immunological studies.
Molecular immunology 2004;40(13):943-8.
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2004: Liskamp Rob M J; Kruijtzer John A W
Peptide transformation leading to peptide-peptidosulfonamide hybrids and oligo peptidosulfonamides.
Molecular diversity 2004;8(2):79-87.
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2003: Autar Reshma; Khan A Salam; Schad Matthias; Hacker Jörg; Liskamp Rob M J; Pieters Roland J
Adhesion inhibition of F1C-fimbriated Escherichia coli and Pseudomonas aeruginosa PAK and PAO by multivalent carbohydrate ligands.
Chembiochem : a European journal of chemical biology 2003;4(12):1317-25.
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2003: Chamorro Cristina; Liskamp Rob M J
Approaches to the solid phase of a cyclotriveratrylene scaffold-based tripodal library as potential artificial receptors.
Journal of combinatorial chemistry 2003;5(6):794-801.
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2003: Dekker Frank J; de Mol Nico J; Fischer Marcel J E; Kemmink Johan; Liskamp Rob M J
Cyclic phosphopeptides for interference with Grb2 SH2 domain signal transduction prepared by ring-closing metathesis and phosphorylation.
Organic & biomolecular chemistry 2003;1(19):3297-303.
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2003: van Ameijde Jeroen; Liskamp Rob M J
Synthesis of novel trivalent amino acid glycoconjugates based on the cyclotriveratrylene ('CTV') scaffold.
Organic & biomolecular chemistry 2003;1(15):2661-9.
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2003: Dekker Frank J; de Mol Nico J; Fischer Marcel J E; Liskamp Rob M J
Amino propynyl benzoic acid building block in rigid spacers of divalent ligands binding to the Syk SH2 domains with equally high affinity as the natural ligand.
Bioorganic & medicinal chemistry letters 2003;13(7):1241-4.
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2003: Vrasidas Ioannis; André Sabine; Valentini Paola; Böck Corina; Lensch Martin; Kaltner Herbert; Liskamp Rob M; Gabius Hans-J; Pieters Roland J
Rigidified multivalent lactose molecules and their interactions with mammalian galectins: a route to selective inhibitors.
Organic & biomolecular chemistry 2003;1(5):803-10.
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2003: Dekker Frank J; de Mol Nico J; Bultinck Patrick; Kemmink Johan; Hilbers Hans W; Liskamp Rob M J
Role of solution conformation and flexibility of short peptide ligands that bind to the p56(lck) SH2 domain.
Bioorganic & medicinal chemistry 2003;11(6):941-9.
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2003: Nijenhuis Wouter A J; Kruijtzer John A W; Wanders Nienke; Vrinten Dorien H; Garner Keith M; Schaaper Wim M M; Meloen Rob H; Gispen Willem Hendrik; Liskamp Rob M; Adan Roger A H
Discovery and in vivo evaluation of new melanocortin-4 receptor-selective peptides.
Peptides 2003;24(2):271-80.
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2002: Rump Erik T; Rijkers Dirk T S; Hilbers Hans W; de Groot Philip G; Liskamp Rob M J
Cyclotriveratrylene (CTV) as a new chiral triacid scaffold capable of inducing triple helix formation of collagen peptides containing either a native sequence or Pro-Hyp-Gly repeats.
Chemistry (Weinheim an der Bergstrasse, Germany) 2002;8(20):4613-21.
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2002: Rijkers Dirk T S; Höppener Jo W M; Posthuma George; Lips Cornelis J M; Liskamp Rob M J
Inhibition of amyloid fibril formation of human amylin by N-alkylated amino acid and alpha-hydroxy acid residue containing peptides.
Chemistry (Weinheim an der Bergstrasse, Germany) 2002;8(18):4285-91.
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2002: Opatz Till; Liskamp Rob M J
Synthesis and screening of libraries of synthetic tripodal receptor molecules with three different amino acid or peptide arms: identification of iron binders.
Journal of combinatorial chemistry 2002;4(4):275-84.
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2002: de Planque Maurits R R; Boots Jan-Willem P; Rijkers Dirk T S; Liskamp Rob M J; Greathouse Denise V; Killian J Antoinette
The effects of hydrophobic mismatch between phosphatidylcholine bilayers and transmembrane alpha-helical peptides depend on the nature of interfacially exposed aromatic and charged residues.
Biochemistry 2002;41(26):8396-404.
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2002: Wels Bas; Kruijtzer John A W; Liskamp Rob M J
Synthesis of cyclic (alpha(2)beta)-tripeptides as potential peptide turn mimetics.
Organic letters 2002;4(13):2173-6.
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2002: Strandberg Erik; Morein Sven; Rijkers Dirk T S; Liskamp Rob M J; van der Wel Patrick C A; Killian J Antoinette
Lipid dependence of membrane anchoring properties and snorkeling behavior of aromatic and charged residues in transmembrane peptides.
Biochemistry 2002;41(23):7190-8.
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2002: Halkes S Bart A; Vrasidas Ioannis; Rooijer Gilbert R; van den Berg Albert J J; Liskamp Rob M J; Pieters Roland J
Synthesis and biological activity of polygalloyl-dendrimers as stable tannic acid mimics.
Bioorganic & medicinal chemistry letters 2002;12(12):1567-70.
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2002: de Haan Ellen C; Wauben Marca H M; Grosfeld-Stulemeyer Mayken C; Kruijtzer John A W; Liskamp Rob M J; Moret Ed E
Major histocompatibility complex class II binding characteristics of peptoid-peptide hybrids.
Bioorganic & medicinal chemistry 2002;10(6):1939-45.
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2002: Vrasidas Ioannis; Kemmink Johan; Liskamp Rob M J; Pieters Roland J
Synthesis and cholera toxin binding properties of a lactose-2-aminothiazoline conjugate.
Organic letters 2002;4(10):1807-8.
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2002: Dekker Frank J; de Mol Nico J; van Ameijde Jeroen; Fischer Marcel J E; Ruijtenbeek Rob; Redegeld Frank A M; Liskamp Rob M J
Replacement of the intervening amino acid sequence of a Syk-binding diphosphopeptide by a nonpeptide spacer with preservation of high affinity.
Chembiochem : a European journal of chemical biology 2002;3(2-3):238-42.
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2002: Rijkers Dirk T S; den Hartog Jack A J; Liskamp Rob M J
An optimized solid phase synthesis strategy--including on-resin lactamization--of astressin, its retro-, inverso-, and retro-inverso isomers as corticotropin releasing factor antagonists.
Biopolymers 2002;63(2):141-9.
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2002: Ruijtenbeek Rob; Versluis Cees; Heck Albert J R; Redegeld Frank A M; Nijkamp Frans P; Liskamp Rob M J
Characterization of a phosphorylated peptide and peptoid and peptoid-peptide hybrids by mass spectrometry.
Journal of mass spectrometry : JMS 2002;37(1):47-55.
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2001: Boeijen A; van Ameijde J; Liskamp R M
Solid-phase synthesis of oligourea peptidomimetics employing the Fmoc protection strategy.
The Journal of organic chemistry 2001;66(25):8454-62.
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2001: André S; Pieters R J; Vrasidas I; Kaltner H; Kuwabara I; Liu F T; Liskamp R M; Gabius H J
Wedgelike glycodendrimers as inhibitors of binding of mammalian galectins to glycoproteins, lactose maxiclusters, and cell surface glycoconjugates.
Chembiochem : a European journal of chemical biology 2001;2(11):822-30.
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2001: Opatz T; Liskamp R M
A selectively deprotectable triazacyclophane scaffold for the construction of artificial receptors.
Organic letters 2001;3(22):3499-502.
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2001: Monnee M C; Brouwer A J; Verbeek L M; van Wageningen A M; Liskamp R M
Bio-inspired synthetic receptor molecules towards mimicry of vancomycin.
Bioorganic & medicinal chemistry letters 2001;11(12):1521-5.
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2001: de Planque M R; Goormaghtigh E; Greathouse D V; Koeppe R E; Kruijtzer J A; Liskamp R M; de Kruijff B; Killian J A
Sensitivity of single membrane-spanning alpha-helical peptides to hydrophobic mismatch with a lipid bilayer: effects on backbone structure, orientation, and extent of membrane incorporation.
Biochemistry 2001;40(16):5000-10.
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2001: Ruijtenbeek R; Kruijtzer J A; van de Wiel W; Fischer M J; Flück M; Redegeld F A; Liskamp R M; Nijkamp F P
Peptoid - peptide hybrids that bind Syk SH2 domains involved in signal transduction.
Chembiochem : a European journal of chemical biology 2001;2(3):171-9.
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2000: Reichwein J F; Versluis C; Liskamp R M
Synthesis of cyclic peptides by ring-closing metathesis.
The Journal of organic chemistry 2000;65(19):6187-95.
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1999: van Dijk-Wolthuis W N; van de Wetering P; Hinrichs W L; Hofmeyer L J; Liskamp R M; Crommelin D J; Hennink W E
A versatile method for the conjugation of proteins and peptides to poly[2-(dimethylamino)ethyl methacrylate].
Bioconjugate chemistry 1999;10(4):687-92.
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1999: de Planque M R; Kruijtzer J A; Liskamp R M; Marsh D; Greathouse D V; Koeppe R E; de Kruijff B; Killian J A
Different membrane anchoring positions of tryptophan and lysine in synthetic transmembrane alpha-helical peptides.
The Journal of biological chemistry 1999;274(30):20839-46.
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1999: de Bont D B; Sliedregt-Bol K M; Hofmeyer L J; Liskamp R M
Increased stability of peptidesulfonamide peptidomimetics towards protease catalyzed degradation.
Bioorganic & medicinal chemistry 1999;7(6):1043-7.
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1998: Boeijen A; Kruijtzer J A; Liskamp R M
Combinatorial chemistry of hydantoins.
Bioorganic & medicinal chemistry letters 1998;8(17):2375-80.
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1996: de Bont D B; Moree W J; Liskamp R M
Molecular diversity of peptidomimetics: approaches to the solid-phase synthesis of peptidosulfonamides.
Bioorganic & medicinal chemistry 1996;4(5):667-72.
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1996: Heerma W; Versluis C; de Koster C G; Kruijtzer J A; Zigrovic I; Liskamp R M
Comparing mass spectrometric characteristics of peptides and peptoids.
Rapid communications in mass spectrometry : RCM 1996;10(4):459-64.
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1995: Moree W J; Schouten A; Kroon J; Liskamp R M
Peptides containing the sulfonamide transition-state isostere: synthesis and structure of N-acetyl-tauryl-L-proline methylamide.
International journal of peptide and protein research 1995;45(6):501-7.
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1993: Verhoeven A J; Leusen J H; Kessels G C; Hilarius P M; de Bont D B; Liskamp R M
Inhibition of neutrophil NADPH oxidase assembly by a myristoylated pseudosubstrate of protein kinase C.
The Journal of biological chemistry 1993;268(25):18593-8.
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1993: Nijenhuis A A; Fokkens R H; Nibbering N M; van Oijen A H; de Bont H B; Liskamp R M; van Boom J H
Verification of the position of the phosphate group in some synthetic phosphopeptides by fast-atom bombardment and tandem mass spectrometry.
Rapid communications in mass spectrometry : RCM 1993;7(8):774-9.
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1993: Eichholtz T; de Bont D B; de Widt J; Liskamp R M; Ploegh H L
A myristoylated pseudosubstrate peptide, a novel protein kinase C inhibitor.
The Journal of biological chemistry 1993;268(3):1982-6.
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1992: van der Klein-de Gunst F J; van Boom J H; Liskamp R M
Computer-aided molecular modeling and design of DNA-inserting molecules.
Journal of computer-aided molecular design 1992;6(1):33-46.
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1991: O'Brian C A; Ward N E; Liskamp R M; de Bont D B; Earnest L E; van Boom J H; Fan D
A novel N-myristylated synthetic octapeptide inhibits protein kinase C activity and partially reverses murine fibrosarcoma cell resistance to adriamycin.
Investigational new drugs 1991;9(2):169-79.
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1990: Ioannides C G; Freedman R S; Liskamp R M; Ward N E; O'Brian C A
Inhibition of IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat by a novel peptide inhibitor of protein kinase C.
Cellular immunology 1990;131(1):242-52.
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1990: O'Brian C A; Ioannides C G; Ward N E; Liskamp R M
Inhibition of protein kinase C and calmodulin by the geometric isomers cis- and trans-tamoxifen.
Biopolymers 1990;29(1):97-104.
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1990: O'Brian C A; Ward N E; Liskamp R M; de Bont D B; van Boom J H
N-myristyl-Lys-Arg-Thr-Leu-Arg: a novel protein kinase C inhibitor.
Biochemical pharmacology 1990;39(1):49-57.
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1989: de Bont H B; Liskamp R M; O'Brian C A; Erkelens C; Veeneman G H; van Boom J H
Synthesis of a substrate of protein kinase C and its corresponding phosphopeptide.
International journal of peptide and protein research 1989;33(2):115-23.
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1986: O'Brian C A; Liskamp R M; Solomon D H; Weinstein I B
Triphenylethylenes: a new class of protein kinase C inhibitors.
Journal of the National Cancer Institute 1986;76(6):1243-6.
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1985: O'Brian C A; Liskamp R M; Solomon D H; Weinstein I B
Inhibition of protein kinase C by tamoxifen.
Cancer research 1985;45(6):2462-5.
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