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Dan Barouch

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Gregory Q Del Prete; Ronald C Desrosiers; Luis D Giavedoni; Dan H Barouch; Elena Chertova; Jeffrey D Lifson; Preston A Marx; Christopher J Miller; Laura Newman; David H O'Connor; Kelli Oswald; Ranajit Pal; Laura M Parodi; Michael Piatak; Carolyn Reid; James D Roser; Matthew Scarlotta; Brandon F Keele
Comparative characterization of transfection- and infection-derived simian immunodeficiency virus challenge stocks for in vivo nonhuman primate studies.
Eung-Jun Im; Sufen Li; Anna G McNally; Nicholas M Provine; Erica N Borducchi; Fred R Frankel; Dan H Barouch
An attenuated Listeria monocytogenes vector primes more potent simian immunodeficiency virus-specific mucosal immunity than DNA vaccines in mice.
Peter C DeMuth; Paula T Hammond; Bonnie Huang; Joshua A Kramer; Andrew D Miller; Younjin Min; Dan H Barouch; Darrell J Irvine
Polymer multilayer tattooing for enhanced DNA vaccination.

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2013: Gregory Q Del Prete; Ronald C Desrosiers; Luis D Giavedoni; Dan H Barouch; Elena Chertova; Jeffrey D Lifson; Preston A Marx; Christopher J Miller; Laura Newman; David H O'Connor; Kelli Oswald; Ranajit Pal; Laura M Parodi; Michael Piatak; Carolyn Reid; James D Roser; Matthew Scarlotta; Brandon F Keele
Comparative characterization of transfection- and infection-derived simian immunodeficiency virus challenge stocks for in vivo nonhuman primate studies.
Journal of virology 2013;87(8):4584-95.
2013: Eung-Jun Im; Sufen Li; Anna G McNally; Nicholas M Provine; Erica N Borducchi; Fred R Frankel; Dan H Barouch
An attenuated Listeria monocytogenes vector primes more potent simian immunodeficiency virus-specific mucosal immunity than DNA vaccines in mice.
Journal of virology 2013;87(8):4751-5.
2013: Peter C DeMuth; Paula T Hammond; Bonnie Huang; Joshua A Kramer; Andrew D Miller; Younjin Min; Dan H Barouch; Darrell J Irvine
Polymer multilayer tattooing for enhanced DNA vaccination.
Nature materials 2013;12(4):367-76.
2013: Karina Yusim; Erica Borducchi; Rebecca Dilan; William Fischer; Elena Giorgi; Bette Korber; Joseph Marcotrigiano; Kelly Stanley; James Theiler; Dan H Barouch
Hepatitis C genotype 1 mosaic vaccines are immunogenic in mice and induce stronger T-cell responses than natural strains.
Clinical and vaccine immunology : CVI 2013;20(2):302-5.
2013: Wendy G Tan; Erin E West; Andreas Wieland; Michael J Zilliox; Dan H Barouch; Hyun-Tak Jin; M Juliana McElrath; Pablo Penaloza-MacMaster; Rafi Ahmed
Comparative analysis of simian immunodeficiency virus gag-specific effector and memory CD8+ T cells induced by different adenovirus vectors.
Journal of virology 2013;87(3):1359-72.
2013: Pablo Penaloza-MacMaster; Nicholas M Provine; Joshua Ra; Nathaniel L Simmons; Erica N Borducchi; Mark J Iampietro; Anna McNally; Dan H Barouch
Alternative serotype adenovirus vaccine vectors elicit memory T cells with enhanced anamnestic capacity compared to Ad5 vectors.
Journal of virology 2013;87(3):1373-84.
2013: Lindsey R Baden; Peter Abbink; Ann Cheung; Raphael Dolin; Jaap Goudsmit; M Justin Iampietro; Jennifer A Johnson; Jane Kleinjan; Kathleen H Krause; Hayley Loblein; Alka Patel; Maria G Pau; James Perry; Lauren Peter; Michael S Seaman; Edith Swann; Robert P Tucker; Stephen R Walsh; Mo Weijtens; Mark Wolff; Katherine E Yanosick; Elise Zablowsky; Dan H Barouch
First-in-human evaluation of the safety and immunogenicity of a recombinant adenovirus serotype 26 HIV-1 Env vaccine (IPCAVD 001).
The Journal of infectious diseases 2013;207(2):240-7.
2013: Dan H Barouch; Ann Cheung; Amy Chung; Raphael Dolin; Anne-Sophie Dugast; Nicole Frahm; Jaap Goudsmit; M Justin Iampietro; Jinyan Liu; M Juliana McElrath; Maria G Pau; Lauren Peter; Ulf Reimer; Michael S Seaman; Stephen R Walsh; Mo Weijtens; Holger Wenschuh; Peter Abbink; Galit Alter; Lindsey R Baden
Characterization of humoral and cellular immune responses elicited by a recombinant adenovirus serotype 26 HIV-1 Env vaccine in healthy adults (IPCAVD 001).
The Journal of infectious diseases 2013;207(2):248-56.
2012: Lynda Coughlan; Jerome Custers; Jaap Goudsmit; Stuart A Nicklin; Alan L Parker; Hollie Robinson; Nico Van Roijen; Katie White; Dan H Barouch; Angela C Bradshaw; Andrew H Baker
Ad5:Ad48 hexon hypervariable region substitutions lead to toxicity and increased inflammatory responses following intravenous delivery.
Molecular therapy : the journal of the American Society of Gene Therapy 2012;20(12):2268-81.
2012: Kathryn E Stephenson; James J Szinger; Bette Korber; Mark G Lewis; Adam SanMiguel; Nathaniel L Simmons; Kaitlin Smith; Dan H Barouch
Full-length HIV-1 immunogens induce greater magnitude and comparable breadth of T lymphocyte responses to conserved HIV-1 regions compared with conserved-region-only HIV-1 immunogens in rhesus monkeys.
Journal of virology 2012;86(21):11434-40.
2012: Dennis R Burton; Salvatore T Butera; Shane Crotty; Adam Godzik; Daniel E Kaufmann; M Juliana McElrath; Michel C Nussenzweig; Bali Pulendran; Chris N Scanlan; William R Schief; Guido Silvestri; Hendrik Streeck; Bruce D Walker; Laura M Walker; Andrew B Ward; Ian A Wilson; Rafi Ahmed; Dan H Barouch; Richard Wyatt
A Blueprint for HIV Vaccine Discovery.
Cell host & microbe 2012;12(4):396-407.
2012: Scott A Handley; Amal Kambal; Joshua Kramer; Sheila C Macri; Keith Mansfield; Lori F Maxfield; Andrew D Miller; Sallie R Permar; RM Presti; Joern E Schmitz; Kelly Stanley; Thaddeus S Stappenbeck; Larissa B Thackray; Ronald S Veazey; Peter Abbink; Dan H Barouch; Jason M Brenchley; Lindsay Droit; Erning Duan; David Wang; Guoyan Zhao; Herbert W Virgin
Pathogenic simian immunodeficiency virus infection is associated with expansion of the enteric virome.
Cell 2012;151(2):253-66.
2012: Hualin Li; Katherine Masek-Hammerman; Elizabeth G Rhee; Jeffrey E Teigler; peter abbink; Dan H Barouch
Adenovirus serotype 26 utilizes CD46 as a primary cellular receptor and only transiently activates T lymphocytes following vaccination of rhesus monkeys.
Journal of virology 2012;86(19):10862-5.
2012: Jeffrey E Teigler; M Justin Iampietro; Dan H Barouch
Vaccination with adenovirus serotypes 35, 26, and 48 elicits higher levels of innate cytokine responses than adenovirus serotype 5 in rhesus monkeys.
Journal of virology 2012;86(18):9590-8.
2012: Kathryn E Stephenson; Bruce D Walker; Hualin Li; Nelson L Michael; Dan H Barouch
Gag-specific cellular immunity determines in vitro viral inhibition and in vivo virologic control following simian immunodeficiency virus challenges of vaccinated rhesus monkeys.
Journal of virology 2012;86(18):9583-9.
2012: Jinyan Liu; M Justin Iampietro; Hualin Li; Dan H Barouch
Accelerated heterologous adenovirus prime-boost SIV vaccine in neonatal rhesus monkeys.
Journal of virology 2012;86(15):7829-35.
2012: James M Kovacs; Caroline A Miller; Joseph P Nkolola; Hanqin Peng; James Perry; Michael S Seaman; Dan H Barouch; Ann Cheung; Bing Chen
HIV-1 envelope trimer elicits more potent neutralizing antibody responses than monomeric gp120.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(30):12111-6.
2012: Kathryn E Stephenson; Susan P Buchbinder; John Hural; Faruk Sinangil; Dan H Barouch
Preexisting adenovirus seropositivity is not associated with increased HIV-1 acquisition in three HIV-1 vaccine efficacy trials.
The Journal of infectious diseases 2012;205(12):1806-10.
2012: Matthieu Perreau; Lambert Potin; Hugh C Welles; Celine Pellaton; Dan H Barouch; Andrew J Bett; Danilo R Casimiro; Jason Gall; Bebeka Gjoksi; Alexandre Harari; Eric J Kremer; Ricardo Martin; Giuseppe Pantaleo
The number of Toll-like receptor 9-agonist motifs in the adenovirus genome correlates with induction of dendritic cell maturation by adenovirus immune complexes.
Journal of virology 2012;86(11):6279-85.
2012: Dan H Barouch; Jason Dufour; Per Johan Klasse; Ronald S Veazey; John P Moore
Macaque studies of vaccine and microbicide combinations for preventing HIV-1 sexual transmission.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(22):8694-8.
2012: Dan H Barouch; Erik A Billings; Angela Carville; Guido Ferrari; Donald N Forthal; Jaap Goudsmit; Vanessa M Hirsch; M Justin Iampietro; Jerome H Kim; Hualin Li; Jinyan Liu; Diana M Lynch; Keith G Mansfield; Mary A Marovich; Lori F Maxfield; Ilnour Ourmanov; Maria G Pau; Mangala Rao; Merlin L Robb; Jerald C Sadoff; Adam SanMiguel; Hanneke Schuitemaker; Michael S Seaman; Donald Stablein; peter abbink; Nelson L Michael
Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys.
Nature 2012;482(7383):89-93.
2011: Lindsey R Baden; Dan H Barouch; William A Blattner; Kara Brandariz; Massimo Cardinali; Olivier D Defawe; Raphael Dolin; Barney S Graham; Yunda Huang; Nidhi Kochar; M Juliana McElrath; Cecilia Morgan; Nina Russell; Magdalena E Sobieszczyk; Georgia D Tomaras
Timing of plasmid cytokine (IL-2/Ig) administration affects HIV-1 vaccine immunogenicity in HIV-seronegative subjects.
The Journal of infectious diseases 2011;204(10):1541-9.
2011: Hualin Li; Jinyan Liu; Diana Lynch; Keith G Mansfield; Angela Carville; Dan H Barouch
Durable mucosal simian immunodeficiency virus-specific effector memory T lymphocyte responses elicited by recombinant adenovirus vectors in rhesus monkeys.
Journal of virology 2011;85(21):11007-15.
2011: David R Kaufman; J Rodrigo Mora; Nathaniel L Simmons; Eduardo J Villablanca; Ashley N Cruz; Jaime De Calisto; Dan H Barouch
Vitamin A deficiency impairs vaccine-elicited gastrointestinal immunity.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(4):1877-83.
2011: John D Altman; Dan H Barouch; John I Bell; Philip J R Goulder; Michael G McHeyzer-Williams; Andrew J McMichael; Paul A H Moss; Mark M Davis
Phenotypic analysis of antigen-specific T lymphocytes. Science. 1996. 274: 94-96.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(1):7-9.
2011: Zaza M Ndhlovu; Thumbi Ndung'u; Alicja Piechocka-Trocha; Seanna Vine; Dan H Barouch; Philip J R Goulder; Kegakilwe C Koofhethile; Ashley McMullen; Bruce D Walker
Mosaic HIV-1 Gag antigens can be processed and presented to human HIV-specific CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(12):6914-24.
2011: Elizabeth G Rhee; Joseph N Blattman; Sudhir P Kasturi; R Phelps Kelley; David R Kaufman; Diana M Lynch; Annalena La Porte; Nathaniel L Simmons; Sarah L Clark; Bali Pulendran; Philip D Greenberg; Dan H Barouch
Multiple innate immune pathways contribute to the immunogenicity of recombinant adenovirus vaccine vectors.
Journal of virology 2011;85(1):315-23.
2010: Andrew B Wilks; Elizabeth C Christian; Michael S Seaman; Piya Sircar; Angela Carville; Carmen E Gomez; Mariano Esteban; Giuseppe Pantaleo; Dan H Barouch; Norman L Letvin; Sallie R Permar
Robust vaccine-elicited cellular immune responses in breast milk following systemic simian immunodeficiency virus DNA prime and live virus vector boost vaccination of lactating rhesus monkeys.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(11):7097-106.
2010: Katherine Masek-Hammerman; Hualin Li; Jinyan Liu; peter abbink; Annalena La Porte; Kara L O'Brien; James B Whitney; Angela Carville; Keith G Mansfield; Dan H Barouch
Mucosal trafficking of vector-specific CD4+ T lymphocytes following vaccination of rhesus monkeys with adenovirus serotype 5.
Journal of virology 2010;84(19):9810-6.
2010: Jinyan Liu; Brandon F Keele; Hui Li; Sheila Keating; Philip J Norris; Angela Carville; Keith G Mansfield; Georgia D Tomaras; Barton F Haynes; Dror Kolodkin-Gal; Norman L Letvin; Beatrice H Hahn; George M Shaw; Dan H Barouch
Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys.
Journal of virology 2010;84(19):10406-12.
2010: Elizabeth G Rhee; R Phelps Kelley; Isha Agarwal; Diana M Lynch; Annalena La Porte; Nathaniel L Simmons; Sarah L Clark; Dan H Barouch
TLR4 ligands augment antigen-specific CD8+ T lymphocyte responses elicited by a viral vaccine vector.
Journal of virology 2010;84(19):10413-9.
2010: Dan H Barouch
Novel adenovirus vector-based vaccines for HIV-1.
Current opinion in HIV and AIDS 2010;5(5):386-90.
2010: So-Yon Lim; Tiffany Chan; Rebecca S Gelman; James B Whitney; Kara L O'Brien; Dan H Barouch; David B Goldstein; Barton F Haynes; Norman L Letvin
Contributions of Mamu-A*01 status and TRIM5 allele expression, but not CCL3L copy number variation, to the control of SIVmac251 replication in Indian-origin rhesus monkeys.
PLoS genetics 2010;6(6):e1000997.
2010: David R Kaufman; Maytal Bivas-Benita; Nathaniel L Simmons; Darby Miller; Dan H Barouch
Route of adenovirus-based HIV-1 vaccine delivery impacts the phenotype and trafficking of vaccine-elicited CD8+ T lymphocytes.
Journal of virology 2010;84(12):5986-96.
2010: Joseph P Nkolola; Hanqin Peng; Ethan C Settembre; Michael Freeman; Lauren Grandpre; Colleen Devoy; Diana M Lynch; Annalena La Porte; Nathaniel L Simmons; Ritu Bradley; David C Montefiori; Michael S Seaman; Bing Chen; Dan H Barouch
Breadth of neutralizing antibodies elicited by stable, homogeneous clade A and clade C HIV-1 gp140 envelope trimers in guinea pigs.
Journal of virology 2010;84(7):3270-9.
2010: Dan H Barouch; Kara L O'Brien; Nathaniel L Simmons; Sharon L King; Peter Abbink; Lori F Maxfield; Ying-Hua Sun; Annalena La Porte; Ambryice M Riggs; Diana M Lynch; Sarah L Clark; Katherine Backus; James R Perry; Michael S Seaman; Angela Carville; Keith G Mansfield; James J Szinger; Will Fischer; Mark Muldoon; Bette Korber
Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys.
Nature medicine 2010;16(3):319-23.
2010: Eric S Rosenberg; Barney S Graham; Ellen S Chan; Ronald J Bosch; Vicki Stocker; Janine Maenza; Martin Markowitz; Susan Little; Paul E Sax; Ann C Collier; Gary Nabel; Suzanne Saindon; Theresa Flynn; Daniel Kuritzkes; Dan H Barouch
Safety and immunogenicity of therapeutic DNA vaccination in individuals treated with antiretroviral therapy during acute/early HIV-1 infection.
PloS one 2010;5(5):e10555.
2010: Dan H Barouch; Bette Korber
HIV-1 vaccine development after STEP.
Annual review of medicine 2010;61():153-67.
2009: Dan H Barouch; Jinyan Liu; Diana M Lynch; Kara L O'Brien; Annalena La Porte; Nathaniel L Simmons; Ambryice M Riggs; Sarah Clark; peter abbink; David C Montefiori; Gary Landucci; Donald N Forthal; Steven G Self; Angela Carville; Keith Mansfield; Jaap Goudsmit
Protective efficacy of a single immunization of a chimeric adenovirus vector-based vaccine against simian immunodeficiency virus challenge in rhesus monkeys.
Journal of virology 2009;83(18):9584-90.
2009: Michael G Hudgens; Peter B Gilbert; John R Mascola; Chih-Da Wu; Dan H Barouch; Steven G Self
Power to detect the effects of HIV vaccination in repeated low-dose challenge experiments.
The Journal of infectious diseases 2009;200(4):609-13.
2009: Kara L O'Brien; Jinyan Liu; Sharon L King; Ying-Hua Sun; Joern E Schmitz; Michelle A Lifton; Natalie A Hutnick; Michael R Betts; Sheri A Dubey; Jaap Goudsmit; John W Shiver; Michael N Robertson; Danilo R Casimiro; Dan H Barouch
Adenovirus-specific immunity after immunization with an Ad5 HIV-1 vaccine candidate in humans.
Nature medicine 2009;15(8):873-5.
2009: E G Rhee; Dan H Barouch
Translational Mini-Review Series on Vaccines for HIV: Harnessing innate immunity for HIV vaccine development.
Clinical and experimental immunology 2009;157(2):174-80.
2009: D R Kaufman; Dan H Barouch
Translational Mini-Review Series on Vaccines for HIV: T lymphocyte trafficking and vaccine-elicited mucosal immunity.
Clinical and experimental immunology 2009;157(2):165-73.
2009: Raul Alba; Angela C Bradshaw; Alan L Parker; David Bhella; Simon Waddington; Stuart A Nicklin; Nico van Rooijen; Jerome Custers; Jaap Goudsmit; Dan H Barouch; John H McVey; Andrew H Baker
Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer.
Blood 2009;114(5):965-71.
2009: Lauren Grandpre; Jonathan S Duke-Cohan; Bonnie A Ewald; Colleen Devoy; Dan H Barouch; Norman L Letvin; Ellis L Reinherz; Lindsey R Baden; Raphael Dolin; Michael S Seaman
Immunogenicity of recombinant Modified Vaccinia Ankara following a single or multi-dose vaccine regimen in rhesus monkeys.
Vaccine 2009;27(10):1549-56.
2009: Jinyan Liu; Kara L O'Brien; Diana M Lynch; Nathaniel L Simmons; Annalena La Porte; Ambryice M Riggs; peter abbink; Rory T Coffey; Lauren Grandpre; Michael S Seaman; Gary Landucci; Donald N Forthal; David C Montefiori; Angela Carville; Keith G Mansfield; Menzo J E Havenga; Maria G Pau; Jaap Goudsmit; Dan H Barouch
Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys.
Nature 2009;457(7225):87-91.
2008: Dan H Barouch
Challenges in the development of an HIV-1 vaccine.
Nature 2008;455(7213):613-9.
2008: David R Kaufman; Jinyan Liu; Angela Carville; Keith G Mansfield; Menzo J E Havenga; Jaap Goudsmit; Dan H Barouch
Trafficking of antigen-specific CD8+ T lymphocytes to mucosal surfaces following intramuscular vaccination.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(6):4188-98.
2008: Dan H Barouch
HIV vaccine trial canceled.
AIDS clinical care 2008;20(9):69.
2008: Sampa Santra; Bette T Korber; Mark Muldoon; Dan H Barouch; Gary Nabel; Feng Gao; Beatrice H Hahn; Barton F Haynes; Norman L Letvin
A centralized gene-based HIV-1 vaccine elicits broad cross-clade cellular immune responses in rhesus monkeys.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(30):10489-94.
2008: David R Kaufman; Jaap Goudsmit; Lennart Holterman; Bonnie A Ewald; Matthew Denholtz; Colleen Devoy; Ayush Giri; Lauren Grandpre; Jean-Michel Heraud; Genoveffa Franchini; Michael S Seaman; Menzo J E Havenga; Dan H Barouch
Differential antigen requirements for protection against systemic and intranasal vaccinia virus challenges in mice.
Journal of virology 2008;82(14):6829-37.
2008: Jinyan Liu; Rune Kjeken; Iacob Mathiesen; Dan H Barouch
Recruitment of antigen-presenting cells to the site of inoculation and augmentation of human immunodeficiency virus type 1 DNA vaccine immunogenicity by in vivo electroporation.
Journal of virology 2008;82(11):5643-9.
2008: Dan H Barouch
Bovine adenovirus vectored vaccine for avian influenza.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(5):807-8.
2008: Jinyan Liu; Bonnie A Ewald; Diana M Lynch; Matthew Denholtz; peter abbink; Angelique A C Lemckert; Angela Carville; Keith G Mansfield; Menzo J E Havenga; Jaap Goudsmit; Dan H Barouch
Magnitude and phenotype of cellular immune responses elicited by recombinant adenovirus vectors and heterologous prime-boost regimens in rhesus monkeys.
Journal of virology 2008;82(10):4844-52.
2008: Simon Waddington; John H McVey; David Bhella; Alan L Parker; Kristeen Barker; Hideko Atoda; Rebecca Pink; Suzanne Buckley; Jenny A Greig; Laura Denby; Jerome Custers; Takashi Morita; Ivo M B Francischetti; Robson Q Monteiro; Dan H Barouch; Nico van Rooijen; Claudio Napoli; Menzo J E Havenga; Stuart A Nicklin; Andrew H Baker
Adenovirus serotype 5 hexon mediates liver gene transfer.
Cell 2008;132(3):397-409.
2007: Dan H Barouch
HIV-1 vaccine candidate ineffective.
AIDS clinical care 2007;19(11):93.
2007: peter abbink; Angelique A C Lemckert; Bonnie A Ewald; Diana M Lynch; Matthew Denholtz; Shirley Smits; Lennart Holterman; Irma Damen; Ronald Vogels; Anna R Thorner; Kara L O'Brien; Angela Carville; Keith G Mansfield; Jaap Goudsmit; Menzo J E Havenga; Dan H Barouch
Comparative seroprevalence and immunogenicity of six rare serotype recombinant adenovirus vaccine vectors from subgroups B and D.
Journal of virology 2007;81(9):4654-63.
2007: Anna R Thorner; Dan H Barouch
HIV-1 vaccine development: progress and prospects.
Current infectious disease reports 2007;9(1):71-5.
2006: Anna R Thorner; Angelique A C Lemckert; Jaap Goudsmit; Diana M Lynch; Bonnie A Ewald; Matthew Denholtz; Menzo J E Havenga; Dan H Barouch
Immunogenicity of heterologous recombinant adenovirus prime-boost vaccine regimens is enhanced by circumventing vector cross-reactivity.
Journal of virology 2006;80(24):12009-16.
2006: Jinyan Liu; Bonnie A Ewald; Diana M Lynch; Anjali Nanda; Shawn M Sumida; Dan H Barouch
Modulation of DNA vaccine-elicited CD8+ T-lymphocyte epitope immunodominance hierarchies.
Journal of virology 2006;80(24):11991-7.
2006: Anna R Thorner; Ronald Vogels; Jorn Kaspers; Gerrit Jan Weverling; Lennart Holterman; Angelique A C Lemckert; Athmanundh Dilraj; lisa mcnally; Prakash Jeena; Soren Jepsen; peter abbink; Anjali Nanda; Patricia E Swanson; Andrew T Bates; Kara L O'Brien; Menzo J E Havenga; Jaap Goudsmit; Dan H Barouch
Age dependence of adenovirus-specific neutralizing antibody titers in individuals from sub-Saharan Africa.
Journal of clinical microbiology 2006;44(10):3781-3.
2006: Angelique A C Lemckert; Jos M Grimbergen; Shirley Smits; Eric Hartkoorn; Lennart Holterman; Ben Berkhout; Dan H Barouch; Ronald Vogels; Paul H A Quax; Jaap Goudsmit; Menzo J E Havenga
Generation of a novel replication-incompetent adenoviral vector derived from human adenovirus type 49: manufacture on PER.C6 cells, tropism and immunogenicity.
The Journal of general virology 2006;87(Pt 10):2891-9.
2006: Menzo J E Havenga; Ronald Vogels; David Zuijdgeest; Katarina Radosevic; Stefanie Mueller; M Sieuwerts; Frank F Weichold; Irma Damen; Jorn Kaspers; Angelique A C Lemckert; Michelle van Meerendonk; R van der Vlugt; Lennart Holterman; David Hone; Yasir A W Skeiky; Ratna Mintardjo; Gert Gillissen; Dan H Barouch; Jerald C Sadoff; Jaap Goudsmit
Novel replication-incompetent adenoviral B-group vectors: high vector stability and yield in PER.C6 cells.
The Journal of general virology 2006;87(Pt 8):2135-43.
2006: Diane M Roberts; Anjali Nanda; Menzo J E Havenga; peter abbink; Diana M Lynch; Bonnie A Ewald; Jinyan Liu; Anna R Thorner; Patricia E Swanson; Darci A Gorgone; Michelle A Lifton; Angelique A C Lemckert; Lennart Holterman; Bing Chen; Athmanundh Dilraj; Angela Carville; Keith G Mansfield; Jaap Goudsmit; Dan H Barouch
Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity.
Nature 2006;441(7090):239-43.
2006: Dan H Barouch
Rational design of gene-based vaccines.
The Journal of pathology 2006;208(2):283-9.
2005: Anjali Nanda; Diana M Lynch; Jaap Goudsmit; Angelique A C Lemckert; Bonnie A Ewald; Shawn M Sumida; Diana M Truitt; peter abbink; Michael G Kishko; Darci A Gorgone; Michelle A Lifton; Ling Shen; Angela Carville; Keith G Mansfield; Menzo J E Havenga; Dan H Barouch
Immunogenicity of recombinant fiber-chimeric adenovirus serotype 35 vector-based vaccines in mice and rhesus monkeys.
Journal of virology 2005;79(22):14161-8.
2005: Fred W Peyerl; Dan H Barouch; Heidi S Bazick; Edwin R Manuel; Norman L Letvin
Use of molecular beacons for rapid, real-time, quantitative monitoring of cytotoxic T-lymphocyte epitope mutations in simian immunodeficiency virus.
Journal of clinical microbiology 2005;43(9):4773-9.
2005: Angelique A C Lemckert; Shawn M Sumida; Lennart Holterman; Ronald Vogels; Diana M Truitt; Diana M Lynch; Anjali Nanda; Bonnie A Ewald; Darci A Gorgone; Michelle A Lifton; Jaap Goudsmit; Menzo J E Havenga; Dan H Barouch
Immunogenicity of heterologous prime-boost regimens involving recombinant adenovirus serotype 11 (Ad11) and Ad35 vaccine vectors in the presence of anti-ad5 immunity.
Journal of virology 2005;79(15):9694-701.
2005: Dan H Barouch; Zhi-Yong Yang; Wing-Pui Kong; Birgit Korioth-Schmitz; Shawn M Sumida; Diana M Truitt; Michael G Kishko; Janelle C Arthur; Ayako Miura; John R Mascola; Norman L Letvin; Gary Nabel
A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates.
Journal of virology 2005;79(14):8828-34.
2005: Shawn M Sumida; Diana M Truitt; Angelique A C Lemckert; Ronald Vogels; Jerome H H V Custers; Marylyn M Addo; Shahin Lockman; Trevor Peter; Fred W Peyerl; Michael G Kishko; Shawn S Jackson; Darci A Gorgone; Michelle A Lifton; Myron Essex; Bruce D Walker; Jaap Goudsmit; Menzo J E Havenga; Dan H Barouch
Neutralizing antibodies to adenovirus serotype 5 vaccine vectors are directed primarily against the adenovirus hexon protein.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):7179-85.
2005: Sampa Santra; Michael S Seaman; Ling Xu; Dan H Barouch; Carol I Lord; Michelle A Lifton; Darci A Gorgone; Kristin Beaudry; Krisha Svehla; Brent Welcher; Bimal K Chakrabarti; Yue Huang; Zhi-Yong Yang; John R Mascola; Gary Nabel; Norman L Letvin
Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates.
Journal of virology 2005;79(10):6516-22.
2005: Yue Sun; Joern schmitz; Paula M Acierno; Sampa Santra; Ramu A Subbramanian; Dan H Barouch; Darci A Gorgone; Michelle A Lifton; Kristin Beaudry; Kelledy Manson; Valerie Philippon; Ling Xu; Holden T Maecker; John R Mascola; Dennis Panicali; Gary Nabel; Norman L Letvin
Dysfunction of simian immunodeficiency virus/simian human immunodeficiency virus-induced IL-2 expression by central memory CD4+ T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(8):4753-60.
2005: Dan H Barouch; Jennifer Powers; Diana M Truitt; Michael G Kishko; Janelle C Arthur; Fred W Peyerl; Marcelo J Kuroda; Darci A Gorgone; Michelle A Lifton; Carol I Lord; Vanessa M Hirsch; David C Montefiori; Angela Carville; Keith G Mansfield; Kevin Kunstman; Steven Wolinsky; Norman L Letvin
Dynamic immune responses maintain cytotoxic T lymphocyte epitope mutations in transmitted simian immunodeficiency virus variants.
Nature immunology 2005;6(3):247-52.
2005: Dan H Barouch; Gary Nabel
Adenovirus vector-based vaccines for human immunodeficiency virus type 1.
Human gene therapy 2005;16(2):149-56.
2004: Fred W Peyerl; Heidi S Bazick; Michael H Newberg; Dan H Barouch; Joseph Sodroski; Norman L Letvin
Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope.
Journal of virology 2004;78(24):13901-10.
2004: Dan H Barouch; Norman L Letvin; Robert A Seder
The role of cytokine DNAs as vaccine adjuvants for optimizing cellular immune responses.
Immunological reviews 2004;202():266-74.
2004: Shawn M Sumida; Paul F McKay; Diana M Truitt; Michael G Kishko; Janelle C Arthur; Michael S Seaman; Shawn S Jackson; Darci A Gorgone; Michelle A Lifton; Norman L Letvin; Dan H Barouch
Recruitment and expansion of dendritic cells in vivo potentiate the immunogenicity of plasmid DNA vaccines.
The Journal of clinical investigation 2004;114(9):1334-42.
2004: Dan H Barouch; Diana M Truitt; Norman L Letvin
Expression kinetics of the interleukin-2/immunoglobulin (IL-2/Ig) plasmid cytokine adjuvant.
Vaccine 2004;22(23-24):3092-7.
2004: Sampa Santra; Dan H Barouch; Birgit Korioth-Schmitz; Carol I Lord; Georgia R Krivulka; Faye Yu; Margaret H Beddall; Darci A Gorgone; Michelle A Lifton; Ayako Miura; Valerie Philippon; Kelledy Manson; Phillip D Markham; John Parrish; Marcelo J Kuroda; Joern schmitz; Rebecca Gelman; John W Shiver; David C Montefiori; Dennis Panicali; Norman L Letvin
Recombinant poxvirus boosting of DNA-primed rhesus monkeys augments peak but not memory T lymphocyte responses.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(30):11088-93.
2004: Dan H Barouch; Norman L Letvin
HIV escape from cytotoxic T lymphocytes: a potential hurdle for vaccines?
Lancet 2004;364(9428):10-1.
2004: Dan H Barouch; Maria G Pau; Jerome H H V Custers; Wouter Koudstaal; Stefan Kostense; Menzo J E Havenga; Diana M Truitt; Shawn M Sumida; Michael G Kishko; Janelle C Arthur; Birgit Korioth-Schmitz; Michael H Newberg; Darci A Gorgone; Michelle A Lifton; Dennis Panicali; Gary Nabel; Norman L Letvin; Jaap Goudsmit
Immunogenicity of recombinant adenovirus serotype 35 vaccine in the presence of pre-existing anti-Ad5 immunity.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(10):6290-7.
2004: Paul F McKay; Dan H Barouch; Sampa Santra; Shawn M Sumida; Shawn S Jackson; Darci A Gorgone; Michelle A Lifton; Norman L Letvin
Recruitment of different subsets of antigen-presenting cells selectively modulates DNA vaccine-elicited CD4+ and CD8+ T lymphocyte responses.
European journal of immunology 2004;34(4):1011-20.
2004: Shawn M Sumida; Diana M Truitt; Michael G Kishko; Janelle C Arthur; Shawn S Jackson; Darci A Gorgone; Michelle A Lifton; Wouter Koudstaal; Maria G Pau; Stefan Kostense; Menzo J E Havenga; Jaap Goudsmit; Norman L Letvin; Dan H Barouch
Neutralizing antibodies and CD8+ T lymphocytes both contribute to immunity to adenovirus serotype 5 vaccine vectors.
Journal of virology 2004;78(6):2666-73.
2004: Angelique A C Lemckert; Jaap Goudsmit; Dan H Barouch
Challenges in the search for an HIV vaccine.
European journal of epidemiology 2004;19(6):513-6.
2004: Fred W Peyerl; Dan H Barouch; Norman L Letvin
Structural constraints on viral escape from HIV- and SIV-specific cytotoxic T-lymphocytes.
Viral immunology 2004;17(2):144-51.
2003: Fred W Peyerl; Dan H Barouch; Wendy W Yeh; Heidi S Bazick; Jennifer Kunstman; Kevin Kunstman; Steven Wolinsky; Norman L Letvin
Simian-human immunodeficiency virus escape from cytotoxic T-lymphocyte recognition at a structurally constrained epitope.
Journal of virology 2003;77(23):12572-8.
2003: Francisco M Marty; Dan H Barouch; Eoin P Coakley; Lindsey R Baden
Disseminated trichosporonosis caused by Trichosporon loubieri.
Journal of clinical microbiology 2003;41(11):5317-20.
2003: John R Mascola; Mark G Lewis; Thomas C VanCott; Gabriela Stiegler; Hermann Katinger; Michael S Seaman; Kristin Beaudry; Dan H Barouch; Birgit Korioth-Schmitz; Georgia R Krivulka; Anna Sambor; Brent Welcher; Daniel C Douek; David C Montefiori; John W Shiver; Pascal Poignard; Dennis R Burton; Norman L Letvin
Cellular immunity elicited by human immunodeficiency virus type 1/ simian immunodeficiency virus DNA vaccination does not augment the sterile protection afforded by passive infusion of neutralizing antibodies.
Journal of virology 2003;77(19):10348-56.
2003: Ramu A Subbramanian; Marcelo J Kuroda; William A Charini; Dan H Barouch; Cristina Costantino; Sampa Santra; Joern schmitz; Kristi L Martin; Michelle A Lifton; Darci A Gorgone; John W Shiver; Norman L Letvin
Magnitude and diversity of cytotoxic-T-lymphocyte responses elicited by multiepitope DNA vaccination in rhesus monkeys.
Journal of virology 2003;77(18):10113-8.
2003: Dan H Barouch; Paul F McKay; Shawn M Sumida; Sampa Santra; Shawn S Jackson; Darci A Gorgone; Michelle A Lifton; Bimal K Chakrabarti; Ling Xu; Gary Nabel; Norman L Letvin
Plasmid chemokines and colony-stimulating factors enhance the immunogenicity of DNA priming-viral vector boosting human immunodeficiency virus type 1 vaccines.
Journal of virology 2003;77(16):8729-35.
2003: Dan H Barouch; Jennifer Kunstman; Jennifer Glowczwskie; Kevin Kunstman; Michael A Egan; Fred W Peyerl; Sampa Santra; Marcelo J Kuroda; Joern schmitz; Kristin Beaudry; Georgia R Krivulka; Michelle A Lifton; Darci A Gorgone; Steven Wolinsky; Norman L Letvin
Viral escape from dominant simian immunodeficiency virus epitope-specific cytotoxic T lymphocytes in DNA-vaccinated rhesus monkeys.
Journal of virology 2003;77(13):7367-75.
2003: Paul F McKay; Dan H Barouch; Joern schmitz; Ronald S Veazey; Darci A Gorgone; Michelle A Lifton; Kenneth C Williams; Norman L Letvin
Global dysfunction of CD4 T-lymphocyte cytokine expression in simian-human immunodeficiency virus/SIV-infected monkeys is prevented by vaccination.
Journal of virology 2003;77(8):4695-702.
2003: Mary Premenko-Lanier; Paul A Rota; Gary H Rhodes; David verhoeven; Dan H Barouch; Nicholas W Lerche; Norman L Letvin; William Joseph Bellini; Michael B McChesney
DNA vaccination of infants in the presence of maternal antibody: a measles model in the primate.
Virology 2003;307(1):67-75.
2002: Dan H Barouch; Norman L Letvin
Viral evolution and challenges in the development of HIV vaccines.
Vaccine 2002;20 Suppl 4():A66-8.
2002: Dan H Barouch; William C Faquin; Yiping Chen; Igor J Koralnik; Gregory Robbins; Benjamin T Davis
BK virus-associated hemorrhagic cystitis in a Human Immunodeficiency Virus-infected patient.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2002;35(3):326-9.
2002: Sampa Santra; Dan H Barouch; Marcelo J Kuroda; Joern schmitz; Georgia R Krivulka; Kristin Beaudry; Carol I Lord; Michelle A Lifton; Linda S Wyatt; Bernard Moss; Vanessa M Hirsch; Norman L Letvin
Prior vaccination increases the epitopic breadth of the cytotoxic T-lymphocyte response that evolves in rhesus monkeys following a simian-human immunodeficiency virus infection.
Journal of virology 2002;76(12):6376-81.
2002: Dan H Barouch; Jennifer Kunstman; Marcelo J Kuroda; Joern schmitz; Sampa Santra; Fred W Peyerl; Georgia R Krivulka; Kristin Beaudry; Michelle A Lifton; Darci A Gorgone; David C Montefiori; Mark G Lewis; Steven Wolinsky; Norman L Letvin
Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes.
Nature 2002;415(6869):335-9.
2002: Dan H Barouch; Sampa Santra; Klara Tenner-Racz; Paul Racz; Marcelo J Kuroda; Joern schmitz; Shawn S Jackson; Michelle A Lifton; Daniel C Freed; Helen C Perry; Mary-Ellen Davies; John W Shiver; Norman L Letvin
Potent CD4+ T cell responses elicited by a bicistronic HIV-1 DNA vaccine expressing gp120 and GM-CSF.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(2):562-8.
2002: Norman L Letvin; Dan H Barouch; David C Montefiori
Prospects for vaccine protection against HIV-1 infection and AIDS.
Annual review of immunology 2002;20():73-99.
2002: Paul F McKay; Joern schmitz; Dan H Barouch; Marcelo J Kuroda; Michelle A Lifton; Christine E Nickerson; Darci A Gorgone; Norman L Letvin
Vaccine protection against functional CTL abnormalities in simian human immunodeficiency virus-infected rhesus monkeys.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):332-7.
2001: Dan H Barouch; Tong-Ming Fu; David C Montefiori; Mark G Lewis; John W Shiver; Norman L Letvin
Vaccine-elicited immune responses prevent clinical AIDS in SHIV(89.6P)-infected rhesus monkeys.
Immunology letters 2001;79(1-2):57-61.
2001: A Craiu; Dan H Barouch; Xin Xiao Zheng; Marcelo J Kuroda; Joern schmitz; Michelle A Lifton; Tavis Steenbeke; Christine E Nickerson; Kristin Beaudry; J D Frost; Keith A Reimann; Terry B Strom; Norman L Letvin
An IL-2/Ig fusion protein influences CD4+ T lymphocytes in naive and simian immunodeficiency virus-infected Rhesus monkeys.
AIDS research and human retroviruses 2001;17(10):873-86.
2001: Dan H Barouch; Sampa Santra; Marcelo J Kuroda; Joern schmitz; Ronald Plishka; Alicia Buckler-White; A E Gaitan; R Zin; J H Nam; Linda S Wyatt; Michelle A Lifton; Christine E Nickerson; Bernard Moss; David C Montefiori; Vanessa M Hirsch; Norman L Letvin
Reduction of simian-human immunodeficiency virus 89.6P viremia in rhesus monkeys by recombinant modified vaccinia virus Ankara vaccination.
Journal of virology 2001;75(11):5151-8.
2001: Dan H Barouch; A Craiu; Sampa Santra; Michael A Egan; Joern schmitz; Marcelo J Kuroda; Tong-Ming Fu; J H Nam; Linda S Wyatt; Michelle A Lifton; Georgia R Krivulka; Christine E Nickerson; Carol I Lord; Bernard Moss; Mark G Lewis; Vanessa M Hirsch; John W Shiver; Norman L Letvin
Elicitation of high-frequency cytotoxic T-lymphocyte responses against both dominant and subdominant simian-human immunodeficiency virus epitopes by DNA vaccination of rhesus monkeys.
Journal of virology 2001;75(5):2462-7.
2000: Sampa Santra; Dan H Barouch; Shawn S Jackson; Marcelo J Kuroda; Joern schmitz; Michelle A Lifton; A H Sharpe; Norman L Letvin
Functional equivalency of B7-1 and B7-2 for costimulating plasmid DNA vaccine-elicited CTL responses.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(12):6791-5.
2000: Dan H Barouch; Sampa Santra; Joern schmitz; Marcelo J Kuroda; Tong-Ming Fu; W Wagner; M Bilska; A Craiu; Xin Xiao Zheng; Georgia R Krivulka; Kristin Beaudry; Michelle A Lifton; Christine E Nickerson; Wendy Trigona; K Punt; Daniel C Freed; Liming Guan; Sheri Dubey; Danilo R Casimiro; A Simon; Mary-Ellen Davies; Michael A Chastain; Terry B Strom; Rebecca Gelman; David C Montefiori; Mark G Lewis; Emilio A Emini; John W Shiver; Norman L Letvin
Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination.
Science (New York, N.Y.) 2000;290(5491):486-92.
2000: Sampa Santra; Dan H Barouch; A H Sharpe; Norman L Letvin
B7 co-stimulatory requirements differ for induction of immune responses by DNA, protein and recombinant pox virus vaccination.
European journal of immunology 2000;30(9):2650-9.
2000: Dan H Barouch; A Craiu; Marcelo J Kuroda; Joern schmitz; Xin Xiao Zheng; Sampa Santra; J D Frost; Georgia R Krivulka; Michelle A Lifton; CL Crabbs; Gwendolyn J Heidecker; Helen C Perry; Mary-Ellen Davies; H Xie; Christine E Nickerson; Tavis Steenbeke; Carol I Lord; David C Montefiori; Terry B Strom; John W Shiver; Mark G Lewis; Norman L Letvin
Augmentation of immune responses to HIV-1 and simian immunodeficiency virus DNA vaccines by IL-2/Ig plasmid administration in rhesus monkeys.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(8):4192-7.
1998: Dan H Barouch; Sampa Santra; Tavis Steenbeke; Xin Xiao Zheng; Helen C Perry; Mary-Ellen Davies; Daniel C Freed; A Craiu; Terry B Strom; John W Shiver; Norman L Letvin
Augmentation and suppression of immune responses to an HIV-1 DNA vaccine by plasmid cytokine/Ig administration.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(4):1875-82.
1998: Marcelo J Kuroda; Joern schmitz; Dan H Barouch; A Craiu; T M Allen; A Sette; David Ian Watkins; MA Forman; Norman L Letvin
Analysis of Gag-specific cytotoxic T lymphocytes in simian immunodeficiency virus-infected rhesus monkeys by cell staining with a tetrameric major histocompatibility complex class I-peptide complex.
The Journal of experimental medicine 1998;187(9):1373-81.