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Stephen Lloyd

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Physiology

Living Beings

Escherichia coli

Concepts & Ideas

Disorders

DNA Damage

Phenomena

Ultraviolet Rays

Genes & Molecular Sequences

Amino Acid Sequence

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Co-Publications
Name
35
Harris, Thomas
24
Harris, Constance
22
Dodson, ML
20
Minko, Irina
15
McCullough, Amanda
14
Nechev, Lubomir
14
Stone, Michael
12
Rizzo, Carmelo
11
Kozekov, Ivan
8
Guengerich, Peter
7
Merritt, Keither
7
Kanuri, Manorama
6
Kozekova, Albena
6
Kurtz, Andrew
6
Prakash, Louise

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Publications

TOP 3
Mori Hiromi; Ouchida Rika; Hijikata Atsushi; Kitamura Hiroshi; Ohara Osamu; Li Yingqian; Gao Xiang; Yasui Akira; Lloyd R Stephen; Wang Ji-Yang
Deficiency of the oxidative damage-specific DNA glycosylase NEIL1 leads to reduced germinal center B cell expansion.
Chan Michael K; Ocampo-Hafalla Maria T; Vartanian Vladimir; Jaruga Pawel; Kirkali Güldal; Koenig Karen L; Brown Stuart; Lloyd R Stephen; Dizdaroglu Miral; Teebor George W
Targeted deletion of the genes encoding NTH1 and NEIL1 DNA N-glycosylases reveals the existence of novel carcinogenic oxidative damage to DNA.
Minko Irina G; Kozekov Ivan D; Harris Thomas M; Rizzo Carmelo J; Lloyd R Stephen; Stone Michael P
Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.

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All Publications

2009: Mori Hiromi; Ouchida Rika; Hijikata Atsushi; Kitamura Hiroshi; Ohara Osamu; Li Yingqian; Gao Xiang; Yasui Akira; Lloyd R Stephen; Wang Ji-Yang
Deficiency of the oxidative damage-specific DNA glycosylase NEIL1 leads to reduced germinal center B cell expansion.
DNA repair 2009;8(11):1328-32.
2009: Chan Michael K; Ocampo-Hafalla Maria T; Vartanian Vladimir; Jaruga Pawel; Kirkali Güldal; Koenig Karen L; Brown Stuart; Lloyd R Stephen; Dizdaroglu Miral; Teebor George W
Targeted deletion of the genes encoding NTH1 and NEIL1 DNA N-glycosylases reveals the existence of novel carcinogenic oxidative damage to DNA.
DNA repair 2009;8(7):786-94.
2009: Minko Irina G; Kozekov Ivan D; Harris Thomas M; Rizzo Carmelo J; Lloyd R Stephen; Stone Michael P
Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.
Chemical research in toxicology 2009;22(5):759-78.
2009: Huang Hai; Wang Hao; Lloyd R Stephen; Rizzo Carmelo J; Stone Michael P
Conformational interconversion of the trans-4-hydroxynonenal-derived (6S,8R,11S) 1,N(2)-deoxyguanosine adduct when mismatched with deoxyadenosine in DNA.
Chemical research in toxicology 2009;22(1):187-200.
2008: Huang Hai; Wang Hao; Qi Nan; Lloyd R Stephen; Rizzo Carmelo J; Stone Michael P
The stereochemistry of trans-4-hydroxynonenal-derived exocyclic 1,N2-2'-deoxyguanosine adducts modulates formation of interstrand cross-links in the 5'-CpG-3' sequence.
Biochemistry 2008;47(44):11457-72.
2008: Minko Irina G; Yamanaka Kinrin; Kozekov Ivan D; Kozekova Albena; Indiani Chiara; O'Donnell Michael E; Jiang Qingfei; Goodman Myron F; Rizzo Carmelo J; Lloyd R Stephen
Replication bypass of the acrolein-mediated deoxyguanine DNA-peptide cross-links by DNA polymerases of the DinB family.
Chemical research in toxicology 2008;21(10):1983-90.
2008: Kumari Anuradha; Minko Irina G; Harbut Michael B; Finkel Steven E; Goodman Myron F; Lloyd R Stephen
Replication bypass of interstrand cross-link intermediates by Escherichia coli DNA polymerase IV.
The Journal of biological chemistry 2008;283(41):27433-7.
2008: Stone Michael P; Cho Young-Jin; Huang Hai; Kim Hye-Young; Kozekov Ivan D; Kozekova Albena; Wang Hao; Minko Irina G; Lloyd R Stephen; Harris Thomas M; Rizzo Carmelo J
Interstrand DNA cross-links induced by alpha,beta-unsaturated aldehydes derived from lipid peroxidation and environmental sources.
Accounts of chemical research 2008;41(7):793-804.
2008: Minko Irina G; Harbut Michael B; Kozekov Ivan D; Kozekova Albena; Jakobs Petra M; Olson Susan B; Moses Robb E; Harris Thomas M; Rizzo Carmelo J; Lloyd R Stephen
Role for DNA polymerase kappa in the processing of N2-N2-guanine interstrand cross-links.
The Journal of biological chemistry 2008;283(25):17075-82.
2008: Minko Irina G; Kozekov Ivan D; Kozekova Albena; Harris Thomas M; Rizzo Carmelo J; Lloyd R Stephen
Mutagenic potential of DNA-peptide crosslinks mediated by acrolein-derived DNA adducts.
Mutation research 2008;637(1-2):161-72.
2007: Fernandes Priscilla H; Lloyd R Stephen
Mutagenic bypass of the butadiene-derived 2'-deoxyuridine adducts by polymerases eta and zeta.
Mutation research 2007;625(1-2):40-9.
2007: Roy Laura M; Jaruga Pawel; Wood Thomas G; McCullough Amanda K; Dizdaroglu Miral; Lloyd R Stephen
Human polymorphic variants of the NEIL1 DNA glycosylase.
The Journal of biological chemistry 2007;282(21):15790-8.
2007: Wickliffe Jeffrey K; Herring Stacy M; Hallberg Lance M; Galbert Lori A; Masters Oscar E; Ammenheuser Marinel M; Xie Jingwu; Friedberg Errol C; Lloyd R Stephen; Abdel-Rahman Sherif Z; Ward Jonathan B
Detoxification of olefinic epoxides and nucleotide excision repair of epoxide-mediated DNA damage: Insights from animal models examining human sensitivity to 1,3-butadiene.
Chemico-biological interactions 2007;166(1-3):226-31.
2007: Xu Wen; Merritt W Keither; Nechev Lubomir V; Harris Thomas M; Harris Constance M; Lloyd R Stephen; Stone Michael P
Structure of the 1,4-Bis(2'-deoxyadenosin-N(6)-yl)-2S,3S-butanediol intrastrand DNA cross-link arising from butadiene diepoxide in the human N-ras codon 61 sequence.
Chemical research in toxicology 2007;20(2):187-98.
2006: Walker Randall K; McCullough Amanda K; Lloyd R Stephen
Uncoupling of nucleotide flipping and DNA bending by the t4 pyrimidine dimer DNA glycosylase.
Biochemistry 2006;45(47):14192-200.
2006: Golan Gali; Zharkov Dmitry O; Grollman Arthur P; Dodson M L; McCullough Amanda K; Lloyd R Stephen; Shoham Gil
Structure of T4 pyrimidine dimer glycosylase in a reduced imine covalent complex with abasic site-containing DNA.
Journal of molecular biology 2006;362(2):241-58.
2006: Cho Young-Jin; Wang Hao; Kozekov Ivan D; Kozekova Albena; Kurtz Andrew J; Jacob Jaison; Voehler Markus; Smith Jarrod; Harris Thomas M; Rizzo Carmelo J; Lloyd R Stephen; Stone Michael P
Orientation of the crotonaldehyde-derived N2-[3-Oxo-1(S)-methyl-propyl]-dG DNA adduct hinders interstrand cross-link formation in the 5'-CpG-3' sequence.
Chemical research in toxicology 2006;19(8):1019-29.
2006: Fernandes Priscilla H; Hackfeld Linda C; Kozekov Ivan D; Hodge Richard P; Lloyd R Stephen
Synthesis and mutagenesis of the butadiene-derived N3 2'-deoxyuridine adducts.
Chemical research in toxicology 2006;19(7):968-76.
2006: Harbut Michael B; Meador Michael; Dodson M L; Lloyd R S
Modulation of the turnover of formamidopyrimidine DNA glycosylase.
Biochemistry 2006;45(23):7341-6.
2006: Cho Young-Jin; Wang Hao; Kozekov Ivan D; Kurtz Andrew J; Jacob Jaison; Voehler Markus; Smith Jarrod; Harris Thomas M; Lloyd R Stephen; Rizzo Carmelo J; Stone Michael P
Stereospecific formation of interstrand carbinolamine DNA cross-links by crotonaldehyde- and acetaldehyde-derived alpha-CH3-gamma-OH-1,N2-propano-2'-deoxyguanosine adducts in the 5'-CpG-3' sequence.
Chemical research in toxicology 2006;19(2):195-208.
2006: Vartanian Vladimir; Lowell Brian; Minko Irina G; Wood Thomas G; Ceci Jeffrey D; George Shakeeta; Ballinger Scott W; Corless Christopher L; McCullough Amanda K; Lloyd R Stephen
The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(6):1864-9.
2006: Wolfle William T; Johnson Robert E; Minko Irina G; Lloyd R Stephen; Prakash Satya; Prakash Louise
Replication past a trans-4-hydroxynonenal minor-groove adduct by the sequential action of human DNA polymerases iota and kappa.
Molecular and cellular biology 2006;26(1):381-6.
2006: Wickliffe J K; Galbert L A; Ammenheuser M M; Herring S M; Xie J; Masters O E; Friedberg E C; Lloyd R S; Ward J B
3,4-Epoxy-1-butene, a reactive metabolite of 1,3-butadiene, induces somatic mutations in Xpc-null mice.
Environmental and molecular mutagenesis 2006;47(1):67-70.
2005: Cho Young-Jin; Kim Hye-Young; Huang Hai; Slutsky Alvira; Minko Irina G; Wang Hao; Nechev Lubomir V; Kozekov Ivan D; Kozekova Albena; Tamura Pamela; Jacob Jaison; Voehler Markus; Harris Thomas M; Lloyd R Stephen; Rizzo Carmelo J; Stone Michael P
Spectroscopic characterization of interstrand carbinolamine cross-links formed in the 5'-CpG-3' sequence by the acrolein-derived gamma-OH-1,N2-propano-2'-deoxyguanosine DNA adduct.
Journal of the American Chemical Society 2005;127(50):17686-96.
2005: Kanuri Manorama; Nechev Lubomir V; Kiehna Sarah E; Tamura Pamela J; Harris Constance M; Harris Thomas M; Lloyd R Stephen
Evidence for Escherichia coli polymerase II mutagenic bypass of intrastrand DNA crosslinks.
DNA repair 2005;4(12):1374-80.
2005: Sanchez Ana M; Kozekov Ivan D; Harris Thomas M; Lloyd R Stephen
Formation of inter- and intrastrand imine type DNA-DNA cross-links through secondary reactions of aldehydic adducts.
Chemical research in toxicology 2005;18(11):1683-90.
2005: Wolfle William T; Johnson Robert E; Minko Irina G; Lloyd R Stephen; Prakash Satya; Prakash Louise
Human DNA polymerase iota promotes replication through a ring-closed minor-groove adduct that adopts a syn conformation in DNA.
Molecular and cellular biology 2005;25(19):8748-54.
2005: Lloyd R Stephen
Investigations of pyrimidine dimer glycosylases--a paradigm for DNA base excision repair enzymology.
Mutation research 2005;577(1-2):77-91.
2005: Merritt W Keither; Nechev Lubomir V; Scholdberg Tandace A; Dean Stephen M; Kiehna Sarah E; Chang Johanna C; Harris Thomas M; Harris Constance M; Lloyd R Stephen; Stone Michael P
Structure of the 1,4-bis(2'-deoxyadenosin-N6-yl)-2R,3R-butanediol cross-link arising from alkylation of the human N-ras codon 61 by butadiene diepoxide.
Biochemistry 2005;44(30):10081-92.
2005: Merritt W Keither; Kowalczyk Agnieszka; Scholdberg Tandace A; Dean Stephen M; Harris Thomas M; Harris Constance M; Lloyd R Stephen; Stone Michael P
Dual roles of glycosyl torsion angle conformation and stereochemical configuration in butadiene oxide-derived N1 beta-hydroxyalkyl deoxyinosine adducts: a structural perspective.
Chemical research in toxicology 2005;18(7):1098-107.
2005: Fernandes Priscilla H; Kanuri Manorama; Nechev Lubomir V; Harris Thomas M; Lloyd R Stephen
Mammalian cell mutagenesis of the DNA adducts of vinyl chloride and crotonaldehyde.
Environmental and molecular mutagenesis 2005;45(5):455-9.
2005: Scholdberg Tandace A; Merritt W Keither; Dean Stephen M; Kowalcyzk Agnieska; Harris Constance M; Harris Thomas M; Rizzo Carmelo J; Lloyd R Stephen; Stone Michael P
Structure of an oligodeoxynucleotide containing a butadiene oxide-derived N1 beta-hydroxyalkyl deoxyinosine adduct in the human N-ras codon 61 sequence.
Biochemistry 2005;44(9):3327-37.
2005: Minko Irina G; Kurtz Andrew J; Croteau Deborah L; Van Houten Bennett; Harris Thomas M; Lloyd R Stephen
Initiation of repair of DNA-polypeptide cross-links by the UvrABC nuclease.
Biochemistry 2005;44(8):3000-9.
2005: Scholdberg Tandace A; Nechev Lubomir V; Merritt W Keither; Harris Thomas M; Harris Constance M; Lloyd R Stephen; Stone Michael P
Mispairing of a site specific major groove (2S,3S)-N6-(2,3,4-trihydroxybutyl)-2'-deoxyadenosyl DNA Adduct of butadiene diol epoxide with deoxyguanosine: formation of a dA(anti).dG(anti) pairing interaction.
Chemical research in toxicology 2005;18(2):145-53.
2004: Manuel Raymond C; Hitomi Kenichi; Arvai Andrew S; House Paul G; Kurtz Andrew J; Dodson M L; McCullough Amanda K; Tainer John A; Lloyd R Stephen
Reaction intermediates in the catalytic mechanism of Escherichia coli MutY DNA glycosylase.
The Journal of biological chemistry 2004;279(45):46930-9.
2004: Kossykh Valeri G; Lloyd R Stephen
A DNA adenine methyltransferase of Escherichia coli that is cell cycle regulated and essential for viability.
Journal of bacteriology 2004;186(18):6340.
2004: Merritt W Keither; Scholdberg Tandace A; Nechev Lubomir V; Harris Thomas M; Harris Constance M; Lloyd R Stephen; Stone Michael P
Stereospecific structural perturbations arising from adenine N(6) butadiene triol adducts in duplex DNA.
Chemical research in toxicology 2004;17(8):1007-19.
2004: Washington M Todd; Minko Irina G; Johnson Robert E; Haracska Lajos; Harris Thomas M; Lloyd R Stephen; Prakash Satya; Prakash Louise
Efficient and error-free replication past a minor-groove N2-guanine adduct by the sequential action of yeast Rev1 and DNA polymerase zeta.
Molecular and cellular biology 2004;24(16):6900-6.
2004: Washington M Todd; Minko Irina G; Johnson Robert E; Wolfle William T; Harris Thomas M; Lloyd R Stephen; Prakash Satya; Prakash Louise
Efficient and error-free replication past a minor-groove DNA adduct by the sequential action of human DNA polymerases iota and kappa.
Molecular and cellular biology 2004;24(13):5687-93.
2004: Scholdberg Tandace A; Nechev Lubomir V; Merritt W Keither; Harris Thomas M; Harris Constance M; Lloyd R Stephen; Stone Michael P
Structure of a site specific major groove (2S,3S)-N6-(2,3,4-trihydroxybutyl)-2'-deoxyadenosyl DNA adduct of butadiene diol epoxide.
Chemical research in toxicology 2004;17(6):717-30.
2004: Zou Yue; Ma Huaxian; Minko Irina G; Shell Steven M; Yang Zhengguan; Qu Youxing; Xu Ying; Geacintov Nicholas E; Lloyd R Stephen
DNA damage recognition of mutated forms of UvrB proteins in nucleotide excision repair.
Biochemistry 2004;43(14):4196-205.
2004: Kossykh Valeri G; Lloyd R Stephen
A DNA adenine methyltransferase of Escherichia coli that is cell cycle regulated and essential for viability.
Journal of bacteriology 2004;186(7):2061-7.
2004: Meador Michael G; Rajagopalan Lavanya; Lloyd R Stephen; Dodson M L
Role of His-16 in turnover of T4 pyrimidine dimer glycosylase.
The Journal of biological chemistry 2004;279(5):3348-53.
2003: Sullivan John; Diamond Pamela D; Kaplan Cheryl L; Mader Travis J; Santa RayKay; Lloyd R Stephen
Community outreach as an iterative dialogue among scientists and communities in the Texas gulf coast region.
Mutation research 2003;544(2-3):331-8.
2003: Sanchez Ana M; Minko Irina G; Kurtz Andrew J; Kanuri Manorama; Moriya Masaaki; Lloyd R Stephen
Comparative evaluation of the bioreactivity and mutagenic spectra of acrolein-derived alpha-HOPdG and gamma-HOPdG regioisomeric deoxyguanosine adducts.
Chemical research in toxicology 2003;16(8):1019-28.
2003: Sanchez Ana M; Volk David E; Gorenstein David G; Lloyd R Stephen
Initiation of repair of A/G mismatches is modulated by sequence context.
DNA repair 2003;2(8):863-78.
2003: Hayden R T; Isotalo P A; Parrett T; Wolk D M; Qian X; Roberts G D; Lloyd R V
In situ hybridization for the differentiation of Aspergillus, Fusarium, and Pseudallescheria species in tissue section.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2003;12(1):21-6.
2003: Spivak G; Lloyd R S; Sweder K S
Workshop on DNA repair and related DNA transactions, a conference report.
DNA repair 2003;2(2):235-42.
2003: Kurtz Andrew J; Lloyd R Stephen
1,N2-deoxyguanosine adducts of acrolein, crotonaldehyde, and trans-4-hydroxynonenal cross-link to peptides via Schiff base linkage.
The Journal of biological chemistry 2003;278(8):5970-6.
2003: Minko Irina G; Washington M Todd; Kanuri Manorama; Prakash Louise; Prakash Satya; Lloyd R Stephen
Translesion synthesis past acrolein-derived DNA adduct, gamma -hydroxypropanodeoxyguanosine, by yeast and human DNA polymerase eta.
The Journal of biological chemistry 2003;278(2):784-90.
2003: Wickliffe Jeffrey K; Ammenheuser Marinel M; Salazar James J; Abdel-Rahman Sherif Z; Hastings-Smith Darlene A; Postlethwait Edward M; Lloyd R Stephen; Ward Jonathan B
A model of sensitivity: 1,3-butadiene increases mutant frequencies and genomic damage in mice lacking a functional microsomal epoxide hydrolase gene.
Environmental and molecular mutagenesis 2003;42(2):106-10.
2003: Fernandes Priscilla H; Wang Hao; Rizzo Carmelo J; Lloyd R Stephen
Site-specific mutagenicity of stereochemically defined 1,N2-deoxyguanosine adducts of trans-4-hydroxynonenal in mammalian cells.
Environmental and molecular mutagenesis 2003;42(2):68-74.
2002: Kanuri Manorama; Nechev Lubomir V; Tamura Pamela J; Harris Constance M; Harris Thomas M; Lloyd R Stephen
Mutagenic spectrum of butadiene-derived N1-deoxyinosine adducts and N6,N6-deoxyadenosine intrastrand cross-links in mammalian cells.
Chemical research in toxicology 2002;15(12):1572-80.
2002: Fortune John M; Dickey Jennifer S; Lavrukhin Oleg V; Van Etten James L; Lloyd R Stephen; Osheroff Neil
Site-specific DNA cleavage by Chlorella virus topoisomerase II.
Biochemistry 2002;41(39):11761-9.
2002: Hayden R T; Qian X; Procop G W; Roberts G D; Lloyd R V
In situ hybridization for the identification of filamentous fungi in tissue section.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2002;11(2):119-26.
2002: Kurtz Andrew J; Dodson M L; Lloyd R Stephen
Evidence for multiple imino intermediates and identification of reactive nucleophiles in peptide-catalyzed beta-elimination at abasic sites.
Biochemistry 2002;41(22):7054-64.
2002: Kanuri Manorama; Minko Irina G; Nechev Lubomir V; Harris Thomas M; Harris Constance M; Lloyd R Stephen
Error prone translesion synthesis past gamma-hydroxypropano deoxyguanosine, the primary acrolein-derived adduct in mammalian cells.
The Journal of biological chemistry 2002;277(21):18257-65.
2002: Dodson M L; Lloyd R Stephen
Mechanistic comparisons among base excision repair glycosylases.
Free radical biology & medicine 2002;32(8):678-82.
2002: Kowalczyk Agnieszka; Carmical J Russ; Zou Yue; Van Houten Bennett; Lloyd R Stephen; Harris Constance M; Harris Thomas M
Intrastrand DNA cross-links as tools for studying DNA replication and repair: two-, three-, and four-carbon tethers between the N(2) positions of adjacent guanines.
Biochemistry 2002;41(9):3109-18.
2002: Jaruga Pawel; Jabil Ritche; McCullough Amanda K; Rodriguez Henry; Dizdaroglu Miral; Lloyd R Stephen
Chlorella virus pyrimidine dimer glycosylase excises ultraviolet radiation- and hydroxyl radical-induced products 4,6-diamino-5-formamidopyrimidine and 2,6-diamino-4-hydroxy-5-formamidopyrimidine from DNA.
Photochemistry and photobiology 2002;75(2):85-91.
2002: Minko Irina G; Zou Yue; Lloyd R Stephen
Incision of DNA-protein crosslinks by UvrABC nuclease suggests a potential repair pathway involving nucleotide excision repair.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):1905-9.
2002: Burgess Sarah; Jaruga Pawel; Dodson M L; Dizdaroglu Miral; Lloyd R Stephen
Determination of active site residues in Escherichia coli endonuclease VIII.
The Journal of biological chemistry 2002;277(4):2938-44.
2002: Dodson M L; Kurtz Andrew J; Lloyd R Stephen
T4 endonuclease V: use of NMR and borohydride trapping to provide evidence for covalent enzyme-substrate imine intermediate.
Methods in enzymology 2002;354():202-7.
2001: Fu C; Bardhan S; Cetateanu N D; Wamil B D; Wang Y; Yan H P; Shi E; Carter C; Venkov C; Yakes F M; Page D L; Lloyd R S; Mernaugh R L; Hellerqvist C G
Identification of a novel membrane protein, HP59, with therapeutic potential as a target of tumor angiogenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(12):4182-94.
2001: Dodson M L; Lloyd R S
Backbone dynamics of DNA containing 8-oxoguanine: importance for substrate recognition by base excision repair glycosylases.
Mutation research 2001;487(3-4):93-108.
2001: Kozekov I D; Nechev L V; Sanchez A; Harris C M; Lloyd R S; Harris T M
Interchain cross-linking of DNA mediated by the principal adduct of acrolein.
Chemical research in toxicology 2001;14(11):1482-5.
2001: Dizdaroglu M; Burgess S M; Jaruga P; Hazra T K; Rodriguez H; Lloyd R S
Substrate specificity and excision kinetics of Escherichia coli endonuclease VIII (Nei) for modified bases in DNA damaged by free radicals.
Biochemistry 2001;40(40):12150-6.
2001: Boldogh I; Milligan D; Lee M S; Bassett H; Lloyd R S; McCullough A K
hMYH cell cycle-dependent expression, subcellular localization and association with replication foci: evidence suggesting replication-coupled repair of adenine:8-oxoguanine mispairs.
Nucleic acids research 2001;29(13):2802-9.
2001: Fortune J M; Lavrukhin O V; Gurnon J R; Van Etten J L; Lloyd R S; Osheroff N
Topoisomerase II from Chlorella virus PBCV-1 has an exceptionally high DNA cleavage activity.
The Journal of biological chemistry 2001;276(26):24401-8.
2001: Hazra T K; Muller J G; Manuel R C; Burrows C J; Lloyd R S; Mitra S
Repair of hydantoins, one electron oxidation product of 8-oxoguanine, by DNA glycosylases of Escherichia coli.
Nucleic acids research 2001;29(9):1967-74.
2001: Minko I; Hattman S; Lloyd R S; Kossykh V
Methylation by a mutant T2 DNA [N(6)-adenine] methyltransferase expands the usage of RecA-assisted endonuclease (RARE) cleavage.
Nucleic acids research 2001;29(7):1484-90.
2001: Hayden R T; Qian X; Roberts G D; Lloyd R V
In situ hybridization for the identification of yeastlike organisms in tissue section.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2001;10(1):15-23.
2001: McCullough A K; Sanchez A; Dodson M L; Marapaka P; Taylor J S; Lloyd R S
The reaction mechanism of DNA glycosylase/AP lyases at abasic sites.
Biochemistry 2001;40(2):561-8.
2001: Minko I G; Washington M T; Prakash L; Prakash S; Lloyd R S
Translesion DNA synthesis by yeast DNA polymerase eta on templates containing N2-guanine adducts of 1,3-butadiene metabolites.
The Journal of biological chemistry 2001;276(4):2517-22.
2001: Kanuri M; Finneman J; Harris C M; Harris T M; Lloyd R S
Efficient nonmutagenic replication bypass of DNAs containing beta-adducts of styrene oxide at adenine N(6).
Environmental and molecular mutagenesis 2001;38(4):357-60.
2001: Rodriguez D A; Kowalczyk A; Ward J B; Harris C M; Harris T M; Lloyd R S
Point mutations induced by 1,2-epoxy-3-butene N1 deoxyinosine adducts.
Environmental and molecular mutagenesis 2001;38(4):292-6.
2001: House P G; Volk D E; Thiviyanathan V; Manuel R C; Luxon B A; Gorenstein D G; Lloyd R S
Potential double-flipping mechanism by E. coli MutY.
Progress in nucleic acid research and molecular biology 2001;68():349-64.
2001: Lloyd R S
Processivity of DNA repair enzymes.
Methods in molecular biology (Clifton, N.J.) 2001;160():3-14.
2000: Lavrukhin O V; Lloyd R S
Involvement of phylogenetically conserved acidic amino acid residues in catalysis by an oxidative DNA damage enzyme formamidopyrimidine glycosylase.
Biochemistry 2000;39(49):15266-71.
2000: Nyaga S G; Lloyd R S
Two glycosylase/abasic lyases from Neisseria mucosa that initiate DNA repair at sites of UV-induced photoproducts.
The Journal of biological chemistry 2000;275(31):23569-76.
2000: Volk D E; House P G; Thiviyanathan V; Luxon B A; Zhang S; Lloyd R S; Gorenstein D G
Structural similarities between MutT and the C-terminal domain of MutY.
Biochemistry 2000;39(25):7331-6.
2000: Carmical J R; Kowalczyk A; Zou Y; Van Houten B; Nechev L V; Harris C M; Harris T M; Lloyd R S
Butadiene-induced intrastrand DNA cross-links: a possible role in deletion mutagenesis.
The Journal of biological chemistry 2000;275(26):19482-9.
2000: Vasquez D A; Nyaga S G; Lloyd R S
Purification and characterization of a novel UV lesion-specific DNA glycosylase/AP lyase from Bacillus sphaericus.
Mutation research 2000;459(4):307-16.
2000: Latham G J; Forgacs E; Beard W A; Prasad R; Bebenek K; Kunkel T A; Wilson S H; Lloyd R S
Vertical-scanning mutagenesis of a critical tryptophan in the "minor groove binding track" of HIV-1 reverse transcriptase. Major groove DNA adducts identify specific protein interactions in the minor groove.
The Journal of biological chemistry 2000;275(20):15025-33.
2000: Lavrukhin O V; Fortune J M; Wood T G; Burbank D E; Van Etten J L; Osheroff N; Lloyd R S
Topoisomerase II from Chlorella virus PBCV-1. Characterization of the smallest known type II topoisomerase.
The Journal of biological chemistry 2000;275(10):6915-21.
2000: Piersen C E; McCullough A K; Lloyd R S
AP lyases and dRPases: commonality of mechanism.
Mutation research 2000;459(1):43-53.
2000: Sun L; Li Y; McCullough A K; Wood T G; Lloyd R S; Adams B; Gurnon J R; Van Etten J L
Intron conservation in a UV-specific DNA repair gene encoded by chlorella viruses.
Journal of molecular evolution 2000;50(1):82-92.
2000: Carmical J R; Zhang M; Nechev L; Harris C M; Harris T M; Lloyd R S
Mutagenic potential of guanine N2 adducts of butadiene mono- and diolepoxide.
Chemical research in toxicology 2000;13(1):18-25.
2000: Garvish J F; Lloyd R S
Active-site determination of a pyrimidine dimer glycosylase.
Journal of molecular biology 2000;295(3):479-88.
2000: Carmical J R; Nechev L V; Harris C M; Harris T M; Lloyd R S
Mutagenic potential of adenine N(6) adducts of monoepoxide and diolepoxide derivatives of butadiene.
Environmental and molecular mutagenesis 2000;35(1):48-56.
1999: Volk D E; Thiviyanathan V; House P G; Lloyd R S; Gorenstein D G
1H, 13C and 15N resonance assignments of the C-terminal domain of MutY: an adenine glycosylase active on G:A mismatches.
Journal of biomolecular NMR 1999;14(4):385-6.
1999: Garvish J F; Lloyd R S
The catalytic mechanism of a pyrimidine dimer-specific glycosylase (pdg)/abasic lyase, Chlorella virus-pdg.
The Journal of biological chemistry 1999;274(14):9786-94.
1999: McCullough A K; Dodson M L; Lloyd R S
Initiation of base excision repair: glycosylase mechanisms and structures.
Annual review of biochemistry 1999;68():255-85.
1999: Lloyd R S
The initiation of DNA base excision repair of dipyrimidine photoproducts.
Progress in nucleic acid research and molecular biology 1999;62():155-75.
1998: Zegar I S; Chary P; Jabil R J; Tamura P J; Johansen T N; Lloyd R S; Harris C M; Harris T M; Stone M P
Multiple conformations of an intercalated (-)-(7S,8R,9S, 10R)-N6-[10-(7,8,9,10-tetrahydrobenzo[a]pyrenyl)]-2'-deoxyadenosyl adduct in the N-ras codon 61 sequence.
Biochemistry 1998;37(47):16516-28.
1998: Lloyd R S
Base excision repair of cyclobutane pyrimidine dimers.
Mutation research 1998;408(3):159-70.
1998: McCullough A K; Romberg M T; Nyaga S; Wei Y; Wood T G; Taylor J S; Van Etten J L; Dodson M L; Lloyd R S
Characterization of a novel cis-syn and trans-syn-II pyrimidine dimer glycosylase/AP lyase from a eukaryotic algal virus, Paramecium bursaria chlorella virus-1.
The Journal of biological chemistry 1998;273(21):13136-42.
1998: Lavrukhin O V; Lloyd R S
Mutagenic replication in a human cell extract of DNAs containing site-specific and stereospecific benzo(a)pyrene-7,8-diol-9,10-epoxide DNA adducts placed on the leading and lagging strands.
Cancer research 1998;58(5):887-91.
1997: McNees A G; O'Donnell M; Horton P H; Kim H Y; Kim S J; Harris C M; Harris T M; Lloyd R S
Lack of correlation between in vitro and in vivo replication of precisely defined benz-a-anthracene adducted DNAs.
The Journal of biological chemistry 1997;272(52):33211-9.
1997: McCullough A K; Dodson M L; Schärer O D; Lloyd R S
The role of base flipping in damage recognition and catalysis by T4 endonuclease V.
The Journal of biological chemistry 1997;272(43):27210-7.
1997: McCarthy M J; Rosenblatt J I; Lloyd R S
Kinetics of repair of UV-induced DNA damage in repair-proficient and -deficient cells as determined by quantitative polymerase chain reaction.
Photochemistry and photobiology 1997;66(3):356-62.
1997: Manuel R C; Lloyd R S
Cloning, overexpression, and biochemical characterization of the catalytic domain of MutY.
Biochemistry 1997;36(37):11140-52.
1997: Nyaga S G; Dodson M L; Lloyd R S
Role of specific amino acid residues in T4 endonuclease V that alter nontarget DNA binding.
Biochemistry 1997;36(14):4080-8.
1997: Furuta M; Schrader J O; Schrader H S; Kokjohn T A; Nyaga S; McCullough A K; Lloyd R S; Burbank D E; Landstein D; Lane L; Van Etten J L
Chlorella virus PBCV-1 encodes a homolog of the bacteriophage T4 UV damage repair gene denV.
Applied and environmental microbiology 1997;63(4):1551-6.
1997: Forgacs E; Latham G; Beard W A; Prasad R; Bebenek K; Kunkel T A; Wilson S H; Lloyd R S
Probing structure/function relationships of HIV-1 reverse transcriptase with styrene oxide N2-guanine adducts.
The Journal of biological chemistry 1997;272(13):8525-30.
1997: Chary P; Harris C M; Harris T M; Lloyd R S
Differential tolerance to DNA polymerization by HIV-1 reverse transcriptase on N6 adenine C10R and C10S benzo[a]pyrene-7,8-dihydrodiol 9,10-epoxide-adducted templates.
The Journal of biological chemistry 1997;272(9):5805-13.
1997: Lloyd R S; Cheng X
Mechanistic link between DNA methyltransferases and DNA repair enzymes by base flipping.
Biopolymers 1997;44(2):139-51.
1996: McCullough A K; Schärer O; Verdine G L; Lloyd R S
Structural determinants for specific recognition by T4 endonuclease V.
The Journal of biological chemistry 1996;271(50):32147-52.
1996: Hellerqvist C G; Lloyd R S; Wang E; Bardhan S
Modulation of interleukin-12 mRNA expression in leukocytes of cancer patients treated with CM101.
Annals of the New York Academy of Sciences 1996;795():346-8.
1996: Latham G J; McNees A G; De Corte B; Harris C M; Harris T M; O'Donnell M; Lloyd R S
Comparison of the efficiency of synthesis past single bulky DNA adducts in vivo and in vitro by the polymerase III holoenzyme.
Chemical research in toxicology 1996;9(7):1167-75.
1996: Piersen C E; Prasad R; Wilson S H; Lloyd R S
Evidence for an imino intermediate in the DNA polymerase beta deoxyribose phosphate excision reaction.
The Journal of biological chemistry 1996;271(30):17811-5.
1996: Manuel R C; Czerwinski E W; Lloyd R S
Identification of the structural and functional domains of MutY, an Escherichia coli DNA mismatch repair enzyme.
The Journal of biological chemistry 1996;271(27):16218-26.
1996: McCarthy M J; Rosenblatt J I; Lloyd R S
A modified quantitative polymerase chain reaction assay for measuring gene-specific repair of UV photoproducts in human cells.
Mutation research 1996;363(1):57-66.
1996: Chary P; Lloyd R S
Impact of the stereochemistry of benzo[a]pyrene 7,8-dihydrodiol 9,10-epoxide-deoxyadenosine adducts on resistance to digestion by phosphodiesterases I and II and translesion synthesis with HIV-1 reverse transcriptase.
Chemical research in toxicology 1996;9(2):409-17.
1996: Latham K A; Rajendran S; Carmical J R; Lee J C; Lloyd R S
T4 endonuclease V exists in solution as a monomer and binds to target sites as a monomer.
Biochimica et biophysica acta 1996;1292(2):324-34.
1996: Dizdaroglu M; Zastawny T H; Carmical J R; Lloyd R S
A novel DNA N-glycosylase activity of E. coli T4 endonuclease V that excises 4,6-diamino-5-formamidopyrimidine from DNA, a UV-radiation- and hydroxyl radical-induced product of adenine.
Mutation research 1996;362(1):1-8.
1995: Piersen C E; Prince M A; Augustine M L; Dodson M L; Lloyd R S
Purification and cloning of Micrococcus luteus ultraviolet endonuclease, an N-glycosylase/abasic lyase that proceeds via an imino enzyme-DNA intermediate.
The Journal of biological chemistry 1995;270(40):23475-84.
1995: Latham K A; Manuel R C; Lloyd R S
The interaction of T4 endonuclease V E23Q mutant with thymine dimer- and tetrahydrofuran-containing DNA.
Journal of bacteriology 1995;177(17):5166-8.
1995: Sun B; Latham K A; Dodson M L; Lloyd R S
Studies on the catalytic mechanism of five DNA glycosylases. Probing for enzyme-DNA imino intermediates.
The Journal of biological chemistry 1995;270(33):19501-8.
1995: Latham K A; Lloyd R S
Delta-elimination by T4 endonuclease V at a thymine dimer site requires a secondary binding event and amino acid Glu-23.
Biochemistry 1995;34(27):8796-803.
1995: Chary P; Lloyd R S
In vitro replication by prokaryotic and eukaryotic polymerases on DNA templates containing site-specific and stereospecific benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide adducts.
Nucleic acids research 1995;23(8):1398-405.
1995: Latham G J; Harris C M; Harris T M; Lloyd R S
The efficiency of translesion synthesis past single styrene oxide DNA adducts in vitro is polymerase-specific.
Chemical research in toxicology 1995;8(3):422-30.
1995: Chary P; Latham G J; Robberson D L; Kim S J; Han S; Harris C M; Harris T M; Lloyd R S
In vivo and in vitro replication consequences of stereoisomeric benzo[a]pyrene-7,8-dihydrodiol 9,10-epoxide adducts on adenine N6 at the second position of N-ras codon 61.
The Journal of biological chemistry 1995;270(10):4990-5000.
1995: Latham K A; Taylor J S; Lloyd R S
T4 endonuclease V protects the DNA strand opposite a thymine dimer from cleavage by the footprinting reagents DNase I and 1,10-phenanthroline-copper.
The Journal of biological chemistry 1995;270(8):3765-71.
1995: Manuel R C; Latham K A; Dodson M L; Lloyd R S
Involvement of glutamic acid 23 in the catalytic mechanism of T4 endonuclease V.
The Journal of biological chemistry 1995;270(6):2652-61.
1994: Dodson M L; Michaels M L; Lloyd R S
Unified catalytic mechanism for DNA glycosylases.
The Journal of biological chemistry 1994;269(52):32709-12.
1994: Latham G J; Lloyd R S
Deoxynucleotide polymerization by HIV-1 reverse transcriptase is terminated by site-specific styrene oxide adducts after translesion synthesis.
The Journal of biological chemistry 1994;269(46):28527-30.
1994: Latham K A; Carmical J R; Lloyd R S
Mutation of tryptophan 128 in T4 endonuclease V does not affect glycosylase or abasic site lyase activity.
Biochemistry 1994;33(30):9024-31.
1994: Jones C J; Lloyd R S; Wood R D
Analysis of cells harboring a putative DNA repair gene reveals a lack of evidence for a second independent xeroderma pigmentosum group A correcting gene.
Mutation research 1994;324(4):159-64.
1994: Latham K A; Lloyd R S
T4 endonuclease V. Perspectives on catalysis.
Annals of the New York Academy of Sciences 1994;726():181-96; discussion 196-7.
1993: Latham G J; Zhou L; Harris C M; Harris T M; Lloyd R S
The replication fate of R- and S-styrene oxide adducts on adenine N6 is dependent on both the chirality of the lesion and the local sequence context.
The Journal of biological chemistry 1993;268(31):23427-34.
1993: Hill K E; Lloyd R S; Burk R F
Conserved features of selenoprotein P cDNA.
Biochemical Society transactions 1993;21(4):832-5.
1993: Dodson M L; Schrock R D; Lloyd R S
Evidence for an imino intermediate in the T4 endonuclease V reaction.
Biochemistry 1993;32(32):8284-90.
1993: Higley M; Lloyd R S
Processivity of uracil DNA glycosylase.
Mutation research 1993;294(2):109-16.
1993: Hill K E; Lloyd R S; Burk R F
Conserved nucleotide sequences in the open reading frame and 3' untranslated region of selenoprotein P mRNA.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(2):537-41.
1993: Schrock R D; Lloyd R S
Site-directed mutagenesis of the NH2 terminus of T4 endonuclease V. The position of the alpha NH2 moiety affects catalytic activity.
The Journal of biological chemistry 1993;268(2):880-6.
1993: Mori T; Rinaldy T L; Athwal R S; Kaur G P; Nikaido O; Lloyd R S; Rinaldy A
A xeroderma pigmentosum complementation group A related gene: confirmation using monoclonal antibodies against the cyclobutane dimer and (6-4) photoproduct.
Mutation research 1993;293(2):143-50.
1992: Kaur G P; Rinaldy A; Lloyd R S; Athwal R S
A gene that partially complements xeroderma pigmentosum group A cells maps to human chromosome 8.
Somatic cell and molecular genetics 1992;18(4):371-9.
1992: Hanifin J M; Lloyd R; Okubo K; Guerin L L; Fancher L; Chan S C
Relationship between increased cyclic AMP-phosphodiesterase activity and abnormal adenylyl cyclase regulation in leukocytes from patients with atopic dermatitis.
The Journal of investigative dermatology 1992;98(6 Suppl):100S-105S.
1992: Nickell C; Prince M A; Lloyd R S
Consequences of molecular engineering enhanced DNA binding in a DNA repair enzyme.
Biochemistry 1992;31(17):4189-98.
1992: Cmarik J L; Humphreys W G; Bruner K L; Lloyd R S; Tibbetts C; Guengerich F P
Mutation spectrum and sequence alkylation selectivity resulting from modification of bacteriophage M13mp18 DNA with S-(2-chloroethyl)glutathione. Evidence for a role of S-(2-N7-guanyl)ethyl)glutathione as a mutagenic lesion formed from ethylene dibromide.
The Journal of biological chemistry 1992;267(10):6672-9.
1991: Corbett A H; Zechiedrich E L; Lloyd R S; Osheroff N
Inhibition of eukaryotic topoisomerase II by ultraviolet-induced cyclobutane pyrimidine dimers.
The Journal of biological chemistry 1991;266(29):19666-71.
1991: Schrock R D; Lloyd R S
Reductive methylation of the amino terminus of endonuclease V eradicates catalytic activities. Evidence for an essential role of the amino terminus in the chemical mechanisms of catalysis.
The Journal of biological chemistry 1991;266(26):17631-9.
1991: Nickell C; Lloyd R S
Mutations in endonuclease V that affect both protein-protein association and target site location.
Biochemistry 1991;30(35):8638-48.
1991: Augustine M L; Hamilton R W; Dodson M L; Lloyd R S
Oligonucleotide site directed mutagenesis of all histidine residues within the T4 endonuclease V gene: role in enzyme-nontarget DNA binding.
Biochemistry 1991;30(32):8052-9.
1991: Dodson M L; Prince M A; Anderson W F; Lloyd R S
Site-directed deletion mutagenesis within the T4 endonuclease V gene: dispensable sequences within putative loop regions.
Mutation research 1991;255(1):19-29.
1991: Prince M A; Friedman B; Gruskin E A; Schrock R D; Lloyd R S
Selective metal binding to Cys-78 within endonuclease V causes an inhibition of catalytic activities without altering nontarget and target DNA binding.
The Journal of biological chemistry 1991;266(16):10686-93.
1991: Hill K E; Lloyd R S; Yang J G; Read R; Burk R F
The cDNA for rat selenoprotein P contains 10 TGA codons in the open reading frame.
The Journal of biological chemistry 1991;266(16):10050-3.
1991: Nickell C; Anderson W F; Lloyd R S
Substitution of basic amino acids within endonuclease V enhances nontarget DNA binding.
The Journal of biological chemistry 1991;266(9):5634-42.
1991: Stump D G; Lloyd R S; Chytil F
Site-directed mutagenesis of rat cellular retinol-binding protein. Alteration in binding specificity resulting from mutation of glutamine 108 to arginine.
The Journal of biological chemistry 1991;266(7):4622-30.
1991: Cook R J; Lloyd R S; Wagner C
Isolation and characterization of cDNA clones for rat liver 10-formyltetrahydrofolate dehydrogenase.
The Journal of biological chemistry 1991;266(8):4965-73.
1990: Rinaldy A; Bellew T; Egli E; Lloyd R S
Increased UV resistance in xeroderma pigmentosum group A cells after transformation with a human genomic DNA clone.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(17):6818-22.
1990: Dowd D R; Lloyd R S
Biological significance of facilitated diffusion in protein-DNA interactions. Applications to T4 endonuclease V-initiated DNA repair.
The Journal of biological chemistry 1990;265(6):3424-31.
1989: Dowd D R; Lloyd R S
Site-directed mutagenesis of the T4 endonuclease V gene: the role of arginine-3 in the target search.
Biochemistry 1989;28(22):8699-705.
1989: Hamilton R W; Lloyd R S
Modulation of the DNA scanning activity of the Micrococcus luteus UV endonuclease.
The Journal of biological chemistry 1989;264(29):17422-7.
1989: Dodson M L; Lloyd R S
Structure-function studies of the T4 endonuclease V repair enzyme.
Mutation research 1989;218(2):49-65.
1989: Dowd D R; Lloyd R S
Biological consequences of a reduction in the non-target DNA scanning capacity of a DNA repair enzyme.
Journal of molecular biology 1989;208(4):701-7.
1989: Brian W R; Srivastava P K; Umbenhauer D R; Lloyd R S; Guengerich F P
Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae.
Biochemistry 1989;28(12):4993-9.
1989: Bork R W; Muto T; Beaune P H; Srivastava P K; Lloyd R S; Guengerich F P
Characterization of mRNA species related to human liver cytochrome P-450 nifedipine oxidase and the regulation of catalytic activity.
The Journal of biological chemistry 1989;264(2):910-9.
1989: Lloyd R S; Augustine M L
Site-directed mutagenesis of the T4 endonuclease V gene: mutations which enhance enzyme specific activity at low salt concentrations.
Proteins 1989;6(2):128-38.
1989: Brian W R; Ged C; Bellew T M; Srivastava P K; Bork R W; Umbenhauer D R; Lloyd R S; Guengerich F P
Human liver mephenytoin 4'-hydroxylase cytochrome P-450 proteins and genes.
Drug metabolism reviews 1989;20(2-4):449-65.
1988: Rinaldy A; Dodson M L; Darling T L; Lloyd R S
Gene cloning using cDNA libraries in a differential competition hybridization strategy: application to cloning XP-A related genes.
DNA (Mary Ann Liebert, Inc.) 1988;7(8):563-70.
1988: Ged C; Umbenhauer D R; Bellew T M; Bork R W; Srivastava P K; Shinriki N; Lloyd R S; Guengerich F P
Characterization of cDNAs, mRNAs, and proteins related to human liver microsomal cytochrome P-450 (S)-mephenytoin 4'-hydroxylase.
Biochemistry 1988;27(18):6929-40.
1988: Gruskin E A; Lloyd R S
Molecular analysis of plasmid DNA repair within ultraviolet-irradiated Escherichia coli. II. UvrABC-initiated excision repair and photolyase-catalyzed dimer monomerization.
The Journal of biological chemistry 1988;263(25):12738-43.
1988: Gruskin E A; Lloyd R S
Molecular analysis of plasmid DNA repair within ultraviolet-irradiated Escherichia coli. I. T4 endonuclease V-initiated excision repair.
The Journal of biological chemistry 1988;263(25):12728-37.
1988: Stump D G; Lloyd R S
Site-directed mutagenesis of the T4 endonuclease V gene: role of tyrosine-129 and -131 in pyrimidine dimer-specific binding.
Biochemistry 1988;27(6):1839-43.
1988: Recinos A; Lloyd R S
Site-directed mutagenesis of the T4 endonuclease V gene: role of lysine-130.
Biochemistry 1988;27(6):1832-8.
1988: Lee S G; Ricca G A; Crumley G; Lloyd R S; Drohan W
Modulation of expression of the human gamma interferon gene in E. coli by site-directed mutagenesis.
Biochemical and biophysical research communications 1988;151(1):598-607.
1987: Guengerich F P; Beaune P H; Umbenhauer D R; Churchill P F; Bork R W; Dannan G A; Knodell R G; Lloyd R S; Martin M V
Cytochrome P-450 enzymes involved in genetic polymorphism of drug oxidation in humans.
Biochemical Society transactions 1987;15(4):576-8.
1987: Lloyd R S; Augustine M L
High-frequency spontaneous deletion of DNA sequences flanked by direct DNA repeats which also contain an internal palindrome.
Mutation research 1987;179(2):135-42.
1987: Sherman D R; Lloyd R S; Chytil F
Rat cellular retinol-binding protein: cDNA sequence and rapid retinol-dependent accumulation of mRNA.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(10):3209-13.
1987: Guengerich F P; Umbenhauer D R; Churchill P F; Beaune P H; Böcker R; Knodell R G; Martin M V; Lloyd R S
Polymorphism of human cytochrome P-450.
Xenobiotica; the fate of foreign compounds in biological systems 1987;17(3):311-6.
1987: Higgins K M; Lloyd R S
Purification of the T4 endonuclease V.
Mutation research 1987;183(2):117-21.
1987: Lloyd R S; Dodson M L; Gruskin E A; Robberson D L
T4 endonuclease V promotes the formation of multimeric DNA structures.
Mutation research 1987;183(2):109-15.
1987: Umbenhauer D R; Martin M V; Lloyd R S; Guengerich F P
Cloning and sequence determination of a complementary DNA related to human liver microsomal cytochrome P-450 S-mephenytoin 4-hydroxylase.
Biochemistry 1987;26(4):1094-9.
1986: Recinos A; Augustine M L; Higgins K M; Lloyd R S
Expression of the bacteriophage T4 denV structural gene in Escherichia coli.
Journal of bacteriology 1986;168(2):1014-8.
1986: Beaune P H; Umbenhauer D R; Bork R W; Lloyd R S; Guengerich F P
Isolation and sequence determination of a cDNA clone related to human cytochrome P-450 nifedipine oxidase.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(21):8064-8.
1986: Gruskin E A; Lloyd R S
The DNA scanning mechanism of T4 endonuclease V. Effect of NaCl concentration on processive nicking activity.
The Journal of biological chemistry 1986;261(21):9607-13.
1986: Recinos A; Lloyd R S
Efficient screening of recombinant DNA junctions afforded by probing with synthetic "bridge" oligonucleotides.
Biochemical and biophysical research communications 1986;138(2):945-52.
1986: Lloyd R S; Augustine M L
Cloning and expression of the 3' portion of the T4 denV gene as a lacZ fusion gene.
Mutation research 1986;165(2):89-100.
1982: Hanawalt P C; Cooper P K; Ganesan A K; Lloyd R S; Smith C A; Zolan M E
Repair responses to DNA damage: enzymatic pathways in E coli and human cells.
Journal of cellular biochemistry 1982;18(3):271-83.
1981: Lloyd R S; Hanawalt P C
Expression of the denV gene of bacteriophage T4 cloned in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(5):2796-800.
1980: Lloyd R S; Hanawalt P C; Dodson M L
Processive action of T4 endonuclease V on ultraviolet-irradiated DNA.
Nucleic acids research 1980;8(21):5113-27.
1979: Lloyd R S; Haidle C W; Robberson D L
Bleomycin fragmentation of duplex DNA occurs as staggered single-strand scissions.
Gene 1979;7(3-4):303-16.
1979: Lloyd R S; Haidle C W; Robberson D L
Site specificity of bleomycin-mediated single-strand scissions and alkali-labile damage in duplex DNA.
Gene 1979;7(3-4):289-302.

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