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Cristina Lo Celso

Research Profile

Living Beings

Anatomy

Physiology

Chemicals & Drugs

Procedures

Hematopoietic Stem Cell Transplantation

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Cell Lineage

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Publications

TOP 3
Adam L MacLean; Cristina Lo Celso; Michael P H Stumpf
Population dynamics of normal and leukaemia stem cells in the haematopoietic stem cell niche show distinct regimes where leukaemia will be controlled.
Edwin D Hawkins; Cristina Lo Celso
Subdivision of bone marrow microenvironments: purpose built homes for haematopoietic stem cells.
Roberta Sottocornola; Cristina Lo Celso
Dormancy in the stem cell niche.

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All Publications

2013: Adam L MacLean; Cristina Lo Celso; Michael P H Stumpf
Population dynamics of normal and leukaemia stem cells in the haematopoietic stem cell niche show distinct regimes where leukaemia will be controlled.
Journal of the Royal Society, Interface / the Royal Society 2013;10(81):20120968.
2013: Edwin D Hawkins; Cristina Lo Celso
Subdivision of bone marrow microenvironments: purpose built homes for haematopoietic stem cells.
The EMBO journal 2013;32(2):176-7.
2012: Roberta Sottocornola; Cristina Lo Celso
Dormancy in the stem cell niche.
Stem cell research & therapy 2012;3(2):10.
2011: Cristina Lo Celso; David T Scadden
The haematopoietic stem cell niche at a glance.
Journal of cell science 2011;124(Pt 21):3529-35.
2011: Steven W Lane; Charles P Lin; Cristina Lo Celso; Christine Ragu; David T Scadden; Sebastian Shterental; Stephen M Sykes; Yingzi J Wang; Scott A Armstrong; Lars Bullinger; Francesca Ferraro; D Gary Gilliland; David A Williams
Differential niche and Wnt requirements during acute myeloid leukemia progression.
Blood 2011;118(10):2849-56.
2011: Melanie G Cornejo; Ronald A DePinho; D Gary Gilliland; Tulasi Khandan; Cristina Lo Celso; Cécile K Lopez; Vinciane Mabialah; Philippe Rameau; Paola Rivera-Muñoz; David T Scadden; Stephen M Sykes; Zuzana Tothova; Jon C Aster; Thomas Mercher
Crosstalk between NOTCH and AKT signaling during murine megakaryocyte lineage specification.
Blood 2011;118(5):1264-73.
2011: Sonia Rodriguez; Edward F Srour; Lin Wang; Cristina Lo Celso; Christen Mumaw; Kei-ichi Nakayama; Nadia Carlesso
The SKP2 E3 ligase regulates basal homeostasis and stress-induced regeneration of HSCs.
Blood 2011;117(24):6509-19.
2011: Abel Sanchez-Aguilera; David T Scadden; Kristina Brumme; Adrienne Dorrance; Francesca Ferraro; Chaekyun Kim; Yun-Jung Lee; Cristina Lo Celso; Hongbo R Luo; Subhanjan Mondal; David A Williams
Guanine nucleotide exchange factor Vav1 regulates perivascular homing and bone marrow retention of hematopoietic stem and progenitor cells.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(23):9607-12.
2011: Cristina Lo Celso; Charles P Lin; David T Scadden
In vivo imaging of transplanted hematopoietic stem and progenitor cells in mouse calvarium bone marrow.
Nature protocols 2011;6(1):1-14.
2010: Steven W Lane; Stephen M Sykes; Fatima Al-Shahrour; Sebastian Shterental; Mahnaz Paktinat; Cristina Lo Celso; Jonathan L Jesneck; Benjamin L Ebert; David A Williams; D Gary Gilliland
The Apc(min) mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS.
Blood 2010;115(17):3489-97.
2010: Cristina Lo Celso
Every cloud has a silver lining.
Blood 2010;115(3):438-9.
2009: Gregor B Adams; Ian R Alley; Ung-il Chung; Karissa T Chabner; Nathaniel T Jeanson; Cristina Lo Celso; Emily S Marsters; Min Chen; Lee S Weinstein; Charles P Lin; Henry M Kronenberg; David T Scadden
Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow.
Nature 2009;459(7243):103-7.
2009: Cristina Lo Celso; Heather E Fleming; Juwell W Wu; Cher X Zhao; Sam Miake-Lye; Joji Fujisaki; Daniel Côté; David W Rowe; Charles P Lin; David T Scadden
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche.
Nature 2009;457(7225):92-6.
2008: Paul P Szotek; Henry L Chang; Kristen Brennand; Akihiro Fujino; Rafael Pieretti-Vanmarcke; Cristina Lo Celso; David Dombkowski; Frederic Preffer; Kenneth S Cohen; Jose Teixeira; Patricia K Donahoe
Normal ovarian surface epithelial label-retaining cells exhibit stem/progenitor cell characteristics.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(34):12469-73.
2008: Viktor Janzen; Heather E Fleming; Tamara Riedt; Göran Karlsson; Matthew J Riese; Cristina Lo Celso; Griffin Reynolds; Craig D Milne; Christopher J Paige; Stefan Karlsson; Minna Woo; David T Scadden
Hematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3.
Cell stem cell 2008;2(6):584-94.
2008: Cristina Lo Celso; Melanie A Berta; Kristin Braun; Michaela Frye; Stephen Lyle; Christos Zouboulis; Fiona M Watt
Characterization of bipotential epidermal progenitors derived from human sebaceous gland: contrasting roles of c-Myc and beta-catenin.
Stem cells (Dayton, Ohio) 2008;26(5):1241-52.
2008: Heather E Fleming; Viktor Janzen; Cristina Lo Celso; Jun Guo; Kathleen M Leahy; Henry M Kronenberg; David T Scadden
Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo.
Cell stem cell 2008;2(3):274-83.
2007: Cristina Lo Celso; David T Scadden
Stem cells remember their grade.
Cell stem cell 2007;1(2):132-4.
2007: Cristina Lo Celso; David Scadden
Isolation and transplantation of hematopoietic stem cells (HSCs).
Journal of visualized experiments : JoVE 2007;(2):157.
2006: Soline Estrach; Carrie A Ambler; Cristina Lo Celso; Katsuto Hozumi; Fiona M Watt
Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis.
Development (Cambridge, England) 2006;133(22):4427-38.
2006: Fiona M Watt; Cristina Lo Celso; Violeta Silva-Vargas
Epidermal stem cells: an update.
Current opinion in genetics & development 2006;16(5):518-24.
2006: Kazumasa Morita; Cristina Lo Celso; Bradley Spencer-Dene; Christos Zouboulis; Fiona M Watt
HAN11 binds mDia1 and controls GLI1 transcriptional activity.
Journal of dermatological science 2006;44(1):11-20.
2005: Violeta Silva-Vargas; Cristina Lo Celso; Adam Giangreco; Tyler Ofstad; David Prowse; Kristin Braun; Fiona M Watt
Beta-catenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells.
Developmental cell 2005;9(1):121-31.
2004: Cristina Lo Celso; David Prowse; Fiona M Watt
Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours.
Development (Cambridge, England) 2004;131(8):1787-99.