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Francesco Lo Coco

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Tiziana Ottone; Paola Panetta; Adriano Venditti; Serena Zaza; Enrico Montefusco; Sergio Amadori; Luciana Annino; Claudia Ciardi; Laura Cicconi; Michela Cittadini; Mariadomenica Divona; Annibale Franchi; Jonny Di Giandomenico; Syed Khizer Hasan; Serena Laterza; Serena Lavorgna; Francesco Lo Coco
Identification of emerging FLT3 ITD-positive clones during clinical remission and kinetics of disease relapse in acute myeloid leukaemia with mutated nucleophosmin.
Andrew Chan; Francesco Lo Coco
Mitoxantrone-related acute leukemia in MS: An open or closed book?
Massimo Breccia; Roberto Latagliata; Giuseppina Loglisci; Maria Giovanna Loglisci; Clara Minotti; Adriano Salaroli; Francesco Lo Coco
Influence of time to complete remission and duration of all-trans retinoic acid therapy on the relapse risk in patients with acute promyelocytic leukemia receiving AIDA protocols.

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2013: Tiziana Ottone; Paola Panetta; Adriano Venditti; Serena Zaza; Enrico Montefusco; Sergio Amadori; Luciana Annino; Claudia Ciardi; Laura Cicconi; Michela Cittadini; Mariadomenica Divona; Annibale Franchi; Jonny Di Giandomenico; Syed Khizer Hasan; Serena Laterza; Serena Lavorgna; Francesco Lo Coco
Identification of emerging FLT3 ITD-positive clones during clinical remission and kinetics of disease relapse in acute myeloid leukaemia with mutated nucleophosmin.
British journal of haematology 2013;161(4):533-40.
2013: Andrew Chan; Francesco Lo Coco
Mitoxantrone-related acute leukemia in MS: An open or closed book?
Neurology 2013;80(16):1529-33.
2013: Massimo Breccia; Roberto Latagliata; Giuseppina Loglisci; Maria Giovanna Loglisci; Clara Minotti; Adriano Salaroli; Francesco Lo Coco
Influence of time to complete remission and duration of all-trans retinoic acid therapy on the relapse risk in patients with acute promyelocytic leukemia receiving AIDA protocols.
Leukemia research 2013;37(4):383-5.
2013: Nélida I Noguera; T Ottone; P P Pandolfi; M S Song; S Amadori; L Battistini; K L Calvo; G Catalano; E Colombo; Mariadomenica Divona; I Faraoni; F Florenzano; F García; Francesco Lo Coco
Nucleophosmin/B26 regulates PTEN through interaction with HAUSP in acute myeloid leukemia.
Leukemia 2013;27(5):1037-43.
2013: Eduardo M Rego; Raul C Ribeiro; Guillermo J Ruiz-Argüelles; Stanley L Schrier; Martin Tallman; Maria Soledad Undurraga; Maria del Rosario Uriarte; Nancy Berliner; Rosane Bittencourt; Maria de Lourdes L F Chauffaille; Carlos Sergio Chiattone; Evandro M Fagundes; Robert Gallagher; Arnold Ganser; Javier Garcés-Eisele; David Gómez-Almaguer; David Grimwade; Homero Gutiérrez-Aguirre; Rafael H Jacomo; Haesook T Kim; Hau C Kwaan; Francesco Lo Coco; Bob Löwenberg; Lem Martinez; Luis A Meillón; Raul A M Melo; Charlotte M Niemeyer; Katia Pagnano; Ricardo Pasquini; Miguel A Sanz
Improving acute promyelocytic leukemia (APL) outcome in developing countries through networking, results of the International Consortium on APL.
Blood 2013;121(11):1935-43.
2013: Fabio Efficace; Francesco Lo Coco
Using patient-reported health status to improve prognostic assessment in patients with acute myeloid leukemia: current challenges and future applications.
Haematologica 2013;98(1):7-9.
2012: Girish Chander Gaur; Serena Lavorgna; Laura Cicconi; Jonny Di Giandomenico; Irene Luna; Nélida I Noguera; Safaa M Ramadan; Miguel A Sanz; Esperanza Such; Francesco Lo Coco
Analysis of mutational status, SNP rs16754, and expression levels of Wilms tumor 1 (WT1) gene in acute promyelocytic leukemia.
Annals of hematology 2012;91(12):1855-60.
2012: Farhad Ravandi; Charles Alan Schiffer; Richard A Larson; Francesco Lo Coco; Frederick R Appelbaum; Alan K Burnett; Elihu H Estey; Hagop M Kantarjian
Gemtuzumab ozogamicin: time to resurrect?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(32):3921-3.
2012: Safaa M Ramadan; Cristina Papayannidis; William Arcese; Franco Aversa; Andrea Bacigalupo; Massimo Breccia; Agnese Camboni; Luca Cupelli; Ambra Di Veroli; Anna Paola Iori; Francesco Lo Coco
Allogeneic stem cell transplantation for advanced acute promyelocytic leukemia in the ATRA and ATO era.
Haematologica 2012;97(11):1731-5.
2012: Safaa M Ramadan; Valentina Summa; Tamer M Fouad; Syed Kh Hasan; Francesco Lo Coco
Acute myeloid leukemia developing in patients with autoimmune diseases.
Haematologica 2012;97(6):805-17.
2012: Massimo Breccia; Francesco Lo Coco
Arsenic trioxide for management of acute promyelocytic leukemia: current evidence on its role in front-line therapy and recurrent disease.
Expert opinion on pharmacotherapy 2012;13(7):1031-43.
2012: Giuseppe Zardo; Nélida I Noguera; Serena Racanicchi; Linda Starnes; Lorena Travaglini; Laura Vian; Monia Billi; Giuseppe Cimino; Alberto Ciolfi; Francesco Fazi; Francesco Grignani; Francesco Lo Coco; Marco Mancini; Carmen Maresca; Mauro Nanni; Clara Nervi
Polycombs and microRNA-223 regulate human granulopoiesis by transcriptional control of target gene expression.
Blood 2012;119(17):4034-46.
2012: T Ottone; Maria Pagoni; U Platzbecker; Maria Teresa Voso; L Melillo; Enrico Montefusco; Sergio Amadori; E Barragán; L Cicconi; Mariadomenica Divona; L Giannì; Syed Khizer Hasan; M Hubmann; S Lavorgna; Francesco Lo Coco
Comparative molecular analysis of therapy-related and de novo acute promyelocytic leukemia.
Leukemia research 2012;36(4):474-8.
2012: Francesco Buccisano; Giovanni Del Poeta; Maria Ilaria Del Principe; Francesco Lo Coco; Luca Maurillo; Giuseppe Sconocchia; Sergio Amadori; William Arcese; Adriano Venditti
Prognostic and therapeutic implications of minimal residual disease detection in acute myeloid leukemia.
Blood 2012;119(2):332-41.
2012: Isabella Faraoni; Francesco Fazi; Serena Laterza; Davide Ardiri; Claudia Ciardi; Francesco Lo Coco
MiR-424 and miR-155 deregulated expression in cytogenetically normal acute myeloid leukaemia: correlation with NPM1 and FLT3 mutation status.
Journal of hematology & oncology 2012;5():26.
2011: Laura Cicconi; Mariadomenica Divona; Maria Concetta Petti; Safaa M Ramadan; Atelda Romano; Francesco Lo Coco
Long-term seventh molecular remission in acute promyelocytic leukaemia.
Annals of hematology 2011;90(11):1369-70.
2011: Roberto Latagliata; Francesco Lo Coco; Franco Mandelli; Giovanni Martinelli; Lorella Melillo; Maria Concetta Petti; Serena Rupoli; Flavia Salvi; Marco Sborgia; Anna Tonso; Adriano Venditti; Marco Vignetti; Donatella Vincelli; Giuseppe Avvisati; Massimo Breccia; Anna Candoni; Giuseppe Cimino; Francesco Di Raimondo; Paola Fazi; Maria Grazia Kropp
GIMEMA AIDA 0493 amended protocol for elderly patients with acute promyelocytic leukaemia. Long-term results and prognostic factors.
British journal of haematology 2011;154(5):564-8.
2011: Massimo Breccia; Laura Cicconi; Laura Giannì; Roberto Latagliata; Clara Minotti; Francesco Lo Coco
Efficacy of prolonged therapy with combined arsenic trioxide and ATRA for relapse of acute promyelocytic leukemia.
Haematologica 2011;96(9):1390-1.
2011: Francesco Lo Coco; Miguel A Sanz
Whole-genome sequencing and acute promyelocytic leukemia.
JAMA : the journal of the American Medical Association 2011;306(6):610; author reply 610-1.
2011: Francesco Lo Coco
ED in APL: tip of the iceberg?
Blood 2011;118(5):1188-9.
2011: Laura Cicconi; Vittorio Forte; Graziella Madeo; Nicola Mercuri; Safaa M Ramadan; Francesco Lo Coco
Transient ischemic attack as initial manifestation of acute promyelocytic leukemia.
Leukemia research 2011;35(7):e134-5.
2011: Giuseppe Avvisati; Michele Baccarani; Nicola Cantore; Eros Di Bona; Francesco Di Raimondo; Daniela Diverio; Paola Fazi; Felicetto Ferrara; Giuseppe Fioritoni; Attilio Gabbas; Maria Grazia Kropp; Roberto Latagliata; Francesco Lo Coco; Franco Mandelli; Filippo Marmont; Francesco Nobile; Francesca Paoloni; Maria Concetta Petti; Giovanni Pizzolo; Enrico M Pogliani; Alessandro Rambaldi; Giuseppe Rossi; Giorgina Specchia; Marco Vignetti; Sergio Amadori
AIDA 0493 protocol for newly diagnosed acute promyelocytic leukemia: very long-term results and role of maintenance.
Blood 2011;117(18):4716-25.
2011: Emanuele Ammatuna; Paola Panetta; Xabier Agirre; Tiziana Ottone; Serena Lavorgna; Maria José Calasanz; Francesco Lo Coco
NPM1 gene deletions in myelodysplastic syndromes with 5q- and complex karyotype.
Haematologica 2011;96(5):784-5.
2011: Roberta Riccioni; Elvira Pelosi; Viviana Riti; Germana Castelli; Francesco Lo Coco; Ugo Testa
Immunophenotypic features of acute myeloid leukaemia patients exhibiting high FLT3 expression not associated with mutations.
British journal of haematology 2011;153(1):33-42.
2011: Emanuele Ammatuna; Pau Montesinos; Syed Khizer Hasan; Safaa M Ramadan; Jordi Esteve; Maximillian Hubmann; Maria Pagoni; David Grimwade; Miguel Angel Sanz; Francesco Lo Coco
Presenting features and treatment outcome of acute promyelocytic leukemia arising after multiple sclerosis.
Haematologica 2011;96(4):621-5.
2011: Syed Khizer Hasan; F Buttari; T Ottone; Maria Teresa Voso; S Hohaus; E Marasco; V Mantovani; P Garagnani; M A Sanz; L Cicconi; Giorgio Bernardi; Diego Centonze; Francesco Lo Coco
Risk of acute promyelocytic leukemia in multiple sclerosis: coding variants of DNA repair genes.
Neurology 2011;76(12):1059-65.
2011: Miguel A Sanz; Francesco Lo Coco
Modern approaches to treating acute promyelocytic leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(5):495-503.
2011: Martin S Tallman; Francesco Lo Coco; Hau C Kwaan; Miguel A Sanz; Steven D Gore
Clinical roundtable monograph. Early death in patients with acute promyelocytic leukemia.
Clinical advances in hematology & oncology : H&O 2011;9(2):1-16.
2011: Martin S Tallman; Hau C Kwaan; Francesco Lo Coco; Miguel A Sanz; Steven D Gore
Early death in patients with acute promyelocytic leukemia. Proceedings from a live roundtable at the 2010 American Society of Hematology Annual Meeting, December 4–7, 2010, Orlando, Florida.
Clinical advances in hematology & oncology : H&O 2011;9(2 Suppl 3):1-16.
2011: Massimo Breccia; Francesco Lo Coco
Gemtuzumab ozogamicin for the treatment of acute promyelocytic leukemia: mechanisms of action and resistance, safety and efficacy.
Expert opinion on biological therapy 2011;11(2):225-34.
2010: Maria Cristina Rapanotti; Roberta Caruso; Emanuele Ammatuna; Serena Zaza; Laura Trotta; Mariadomenica Divona; Laura Cicconi; Daria Funaro; Giorgio Federici; Sergio Amadori; Giulio De Rossi; Francesco Lo Coco
Molecular characterization of paediatric idiopathic hypereosinophilia.
British journal of haematology 2010;151(5):440-6.
2010: Francesco Lo Coco; Giuseppe Avvisati; Marco Vignetti; Massimo Breccia; Eugenio Gallo; Alessandro Rambaldi; Francesca Paoloni; Giuseppe Fioritoni; Felicetto Ferrara; Giorgina Specchia; Giuseppe Cimino; Daniela Diverio; Erika Borlenghi; Giovanni Martinelli; Francesco Di Raimondo; Eros Di Bona; Paola Fazi; Antonio Peta; Alberto Bosi; Angelo Michele Carella; Francesco Fabbiano; Enrico M Pogliani; Maria Concetta Petti; Sergio Amadori; Franco Mandelli
Front-line treatment of acute promyelocytic leukemia with AIDA induction followed by risk-adapted consolidation for adults younger than 61 years: results of the AIDA-2000 trial of the GIMEMA Group.
Blood 2010;116(17):3171-9.
2010: Syed Khizer Hasan; Francesco Lo Coco
Utilization of molecular phenotypes to detect relapse and optimize the management of acute promyelocytic leukemia.
Clinical lymphoma, myeloma & leukemia 2010;10 Suppl 3():S139-43.
2010: Ambra Di Veroli; Safaa M Ramadan; Mariadomenica Divona; Laura Cudillo; Laura Giannì; Scott Wieland; Federica Giannotti; Milena Mirabile; William Arcese; Francesco Lo Coco
Molecular remission in advanced acute promyelocytic leukaemia after treatment with the oral synthetic retinoid Tamibarotene.
British journal of haematology 2010;151(1):99-101.
2010: Valentina Lulli; Paolo Romania; Roberta Riccioni; Alessandra Boe; Francesco Lo Coco; Ugo Testa; Giovanna Marziali
Transcriptional silencing of the ETS1 oncogene contributes to human granulocytic differentiation.
Haematologica 2010;95(10):1633-41.
2010: Francesco Buccisano; Luca Maurillo; Alessandra Spagnoli; Maria Ilaria Del Principe; Daniela Fraboni; Paola Panetta; Tiziana Ottone; Maria Irno Consalvo; Serena Lavorgna; Pietro Bulian; Emanuele Ammatuna; Daniela F Angelini; Adamo Diamantini; Selenia Campagna; Licia Ottaviani; Chiara Sarlo; Valter Gattei; Giovanni Del Poeta; William Arcese; Sergio Amadori; Francesco Lo Coco; Adriano Venditti
Cytogenetic and molecular diagnostic characterization combined to postconsolidation minimal residual disease assessment by flow cytometry improves risk stratification in adult acute myeloid leukemia.
Blood 2010;116(13):2295-303.
2010: Alicja M Gruszka; Serena Lavorgna; Maria Irno Consalvo; Tiziana Ottone; Chiara Martinelli; Mario Cinquanta; Giuseppe Ossolengo; Giancarlo Pruneri; Francesco Buccisano; Mariadomenica Divona; Michele Cedrone; Emanuele Ammatuna; Adriano Venditti; Ario de Marco; Francesco Lo Coco; Pier Giuseppe Pelicci
A monoclonal antibody against mutated nucleophosmin 1 for the molecular diagnosis of acute myeloid leukemias.
Blood 2010;116(12):2096-102.
2010: Syed Khizer Hasan; Tiziana Ottone; Richard F Schlenk; Yuanyuan Xiao; Joseph L Wiemels; Maria Enza Mitra; Paolo Bernasconi; Francesco Di Raimondo; Maria Teresa Lupo Stanghellini; Pepa Marco; Ashley N Mays; Hartmut Döhner; Miguel A Sanz; Sergio Amadori; David Grimwade; Francesco Lo Coco
Analysis of t(15;17) chromosomal breakpoint sequences in therapy-related versus de novo acute promyelocytic leukemia: association of DNA breaks with specific DNA motifs at PML and RARA loci.
Genes, chromosomes & cancer 2010;49(8):726-32.
2010: Giovanni Del Poeta; Emanuele Ammatuna; Serena Lavorgna; Giovanni Capelli; Serena Zaza; Fabrizio Luciano; Tiziana Ottone; Maria Ilaria Del Principe; Francesco Buccisano; Luca Maurillo; Paola Panetta; Paolo De Fabritiis; Roberto Stasi; Adriano Venditti; Sergio Amadori; Francesco Lo Coco
The genotype nucleophosmin mutated and FLT3-ITD negative is characterized by high bax/bcl-2 ratio and favourable outcome in acute myeloid leukaemia.
British journal of haematology 2010;149(3):383-7.
2010: Massimo Breccia; Roberto Latagliata; Laura Cannella; Clara Minotti; Giovanna Meloni; Francesco Lo Coco
Early hemorrhagic death before starting therapy in acute promyelocytic leukemia: association with high WBC count, late diagnosis and delayed treatment initiation.
Haematologica 2010;95(5):853-4.
2010: Francesco Lo Coco; Tamer M Fouad; Safaa Ramadan
Acute leukemia in women.
Women's health (London, England) 2010;6(2):239-49.
2010: Hartmut Döhner; Elihu H Estey; Sergio Amadori; Frederick R Appelbaum; Thomas Büchner; Alan K Burnett; Hervé Dombret; Pierre Fenaux; David Grimwade; Richard A Larson; Francesco Lo Coco; Tomoki Naoe; Dietger Niederwieser; Gert Ossenkoppele; MA Sanz; Jorge Sierra; Martin S Tallman; Bob Löwenberg; Clara D Bloomfield
Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet.
Blood 2010;115(3):453-74.
2010: Ashley N Mays; Neil Osheroff; Yuanyuan Xiao; Joseph L Wiemels; Carolyn A Felix; Jo Ann W Byl; Kandeepan Saravanamuttu; Andrew Peniket; Robert Corser; Cherry Chang; Christine Hoyle; Anne Parker; Syed Khizer Hasan; Francesco Lo Coco; Ellen Solomon; David Grimwade
Evidence for direct involvement of epirubicin in the formation of chromosomal translocations in t(15;17) therapy-related acute promyelocytic leukemia.
Blood 2010;115(2):326-30.
2010: Elena Belloni; Stefano Confalonieri; Pp Di Fiore; Patrizia Gasparini; Francesco Lo Coco; B Martino; C Micucci; Paolo Giovanni Nuciforo; C Tapinassi; Maurizio Trubia; Pg Pelicci
Chromosomal rearrangements in acute myeloid leukemia (AML).
Ecancermedicalscience 2010;4():183.
2010: Leonardo Pacilli; Francesco Lo Coco; Safaa Ramadan; Laura Giannì; Alberto Pingi; Daniele Remotti; Ignazio Majolino
Promyelocytic sarcoma of the spine: a case report and review of the literature.
Advances in hematology 2010;2010():137608.
2009: Emanuele Ammatuna; Mariadomenica Divona; Paola Curzi; Paola Panetta; Serena Zaza; Massimiliano Postorino; Maria Cantonetti; Sergio Amadori; Francesco Lo Coco
Simultaneous occurrence of BCR/ABL1 and RUNX1/RUNX1T1 in a case of therapy-related acute myeloid leukemia.
Cancer genetics and cytogenetics 2009;195(2):189-91.
2009: Miguel Sanz; Alan Burnett; Francesco Lo Coco; Bob Löwenberg
FLT3 inhibition as a targeted therapy for acute myeloid leukemia.
Current opinion in oncology 2009;21(6):594-600.
2009: Paola Guglielmelli; Giovanni Barosi; Giorgina Specchia; Alessandro Rambaldi; Francesco Lo Coco; Elisabetta Antonioli; Lisa Pieri; Alessandro Pancrazzi; Vanessa Ponziani; Federica Delaini; Giovanni Longo; Emanuele Ammatuna; Vincenzo Liso; Alberto Bosi; Tiziano Barbui; Alessandro M Vannucchi
Identification of patients with poorer survival in primary myelofibrosis based on the burden of JAK2V617F mutated allele.
Blood 2009;114(8):1477-83.
2009: Emanuele Ammatuna; Annafranca Cavaliere; Mariadomenica Divona; Sergio Amadori; Giovanni Scambia; Francesco Lo Coco
Successful pregnancy after arsenic trioxide therapy for relapsed acute promyelocytic leukaemia.
British journal of haematology 2009;146(3):341.
2009: David Grimwade; Jelena V Jovanovic; Robert K Hills; Elizabeth A Nugent; Yashma Patel; Rajinder Flora; Daniela Diverio; Katy Jones; Hannah Aslett; Elaine Batson; Kristian Rennie; Roger Angell; Richard E Clark; Ellen Solomon; Francesco Lo Coco; Keith Wheatley; Alan K Burnett
Prospective minimal residual disease monitoring to predict relapse of acute promyelocytic leukemia and to direct pre-emptive arsenic trioxide therapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(22):3650-8.
2009: Emanuele Ammatuna; Enrico Montefusco; Matteo Pacilli; Mariadomenica Divona; Davide Ardiri; Diego Centonze; Francesco Lo Coco
Use of arsenic trioxide in secondary acute promyelocytic leukemia developing after treatment of multiple sclerosis with mitoxantrone.
Leukemia & lymphoma 2009;50(7):1217-8.
2009: Tiziana Ottone; Syed Khizer Hasan; Enrico Montefusco; Paola Curzi; Ashley N Mays; Luciana Chessa; Antonella Ferrari; Esmeralda Conte; Nelida Inés Noguera; Serena Lavorgna; Emanuele Ammatuna; Mariadomenica Divona; Katia Bovetti; Sergio Amadori; David Grimwade; Francesco Lo Coco
Identification of a potential "hotspot" DNA region in the RUNX1 gene targeted by mitoxantrone in therapy-related acute myeloid leukemia with t(16;21) translocation.
Genes, chromosomes & cancer 2009;48(3):213-21.
2009: Miguel A Sanz; David Grimwade; Martin S Tallman; Bob Lowenberg; Pierre Fenaux; Elihu H Estey; Tomoki Naoe; Eva Lengfelder; Thomas Büchner; Hartmut Döhner; Alan K Burnett; Francesco Lo Coco
Management of acute promyelocytic leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet.
Blood 2009;113(9):1875-91.
2009: Karina Lucrecia Calvo; Mara Jorgelina Ojeda; Emanuele Ammatuna; Serena Lavorgna; Tiziana Ottone; Hector Manuel Targovnik; Francesco Lo Coco; Nélida Inés Noguera
Detection of the nucleophosmin gene mutations in acute myelogenous leukemia through RT-PCR and polyacrylamide gel electrophoresis.
European journal of haematology 2009;82(1):69-72.
2008: Massimo Breccia; Roberto Latagliata; Ida Carmosino; Laura Cannella; Daniela Diverio; Anna Guarini; Maria Stefania De Propris; Maria Concetta Petti; Giuseppe Avvisati; Giuseppe Cimino; Franco Mandelli; Francesco Lo Coco
Clinical and biological features of acute promyelocytic leukemia patients developing retinoic acid syndrome during induction treatment with all-trans retinoic acid and idarubicin.
Haematologica 2008;93(12):1918-20.
2008: Luca Maurillo; Francesco Buccisano; Maria Ilaria Del Principe; Giovanni Del Poeta; Alessandra Spagnoli; Paola Panetta; Emanuele Ammatuna; Benedetta Neri; Licia Ottaviani; Chiara Sarlo; Daniela Venditti; Micol Quaresima; Raffaella Cerretti; Manuela Rizzo; Paolo De Fabritiis; Francesco Lo Coco; William Arcese; Sergio Amadori; Adriano Venditti
Toward optimization of postremission therapy for residual disease-positive patients with acute myeloid leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(30):4944-51.
2008: Syed Khizer Hasan; Ashley N Mays; Tiziana Ottone; Antonio Ledda; Giorgio La Nasa; Chiara Cattaneo; Erika Borlenghi; Lorella Melillo; Enrico Montefusco; José Cervera; Christopher Stephen; Gnanam Satchi; Anne Lennard; Marta Libura; Jo Ann W Byl; Neil Osheroff; Sergio Amadori; Carolyn A Felix; Maria Teresa Voso; Wolfgang R Sperr; Jordi Esteve; Miguel A Sanz; David Grimwade; Francesco Lo Coco
Molecular analysis of t(15;17) genomic breakpoints in secondary acute promyelocytic leukemia arising after treatment of multiple sclerosis.
Blood 2008;112(8):3383-90.
2008: Min Sup Song; Leonardo Salmena; Arkaitz Carracedo; Ainara Egia; Francesco Lo Coco; Julie T Feldstein; Pier Paolo Pandolfi
The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network.
Nature 2008;455(7214):813-7.
2008: Francesco Lo Coco; Emanuele Ammatuna; Pau Montesinos; Miguel Angel Sanz
Acute promyelocytic leukemia: recent advances in diagnosis and management.
Seminars in oncology 2008;35(4):401-9.
2008: Alessandro M Vannucchi; Elisabetta Antonioli; Paola Guglielmelli; Alessandro Pancrazzi; Vittoria Guerini; Giovanni Barosi; Marco Ruggeri; Giorgina Specchia; Francesco Lo Coco; Federica Delaini; Laura Villani; Silvia Finotto; Emanuele Ammatuna; Renato Alterini; Valentina Carrai; Gloria Capaccioli; Simonetta Di Lollo; Vincenzo Liso; Alessandro Rambaldi; Alberto Bosi; Tiziano Barbui
Characteristics and clinical correlates of MPL 515W>L/K mutation in essential thrombocythemia.
Blood 2008;112(3):844-7.
2008: Francesco Lo Coco; Antonio Cuneo; Fabrizio Pane; Daniela Cilloni; Daniela Diverio; Marco Mancini; Nicoletta Testoni; Antonella Bardi; Barbara Izzo; Niccolò Bolli; Roberta La Starza; Paola Fazi; Simona Iacobelli; Alfonso Piciocchi; Marco Vignetti; Sergio Amadori; Franco Mandelli; Pier Giuseppe Pelicci; Cristina Mecucci; Brunangelo Falini; Giuseppe Saglio
Prognostic impact of genetic characterization in the GIMEMA LAM99P multicenter study for newly diagnosed acute myeloid leukemia.
Haematologica 2008;93(7):1017-24.
2008: Daniela Cilloni; Francesca Messa; Francesca Arruga; Ilaria Defilippi; Enrico Gottardi; Milena Fava; Sonia Carturan; Renata Catalano; Enrico Bracco; Emanuela Messa; Paolo Nicoli; Daniela Diverio; Miguel A Sanz; giovanni martinelli; Francesco Lo Coco; Giuseppe Saglio
Early prediction of treatment outcome in acute myeloid leukemia by measurement of WT1 transcript levels in peripheral blood samples collected after chemotherapy.
Haematologica 2008;93(6):921-4.
2008: Tiziana Ottone; Emanuele Ammatuna; Serena Lavorgna; Nélida I Noguera; Francesco Buccisano; Adriano Venditti; Laura Giannì; Massimiliano Postorino; Giorgio Federici; Sergio Amadori; Francesco Lo Coco
An allele-specific rt-PCR assay to detect type A mutation of the nucleophosmin-1 gene in acute myeloid leukemia.
The Journal of molecular diagnostics : JMD 2008;10(3):212-6.
2008: Brunangelo Falini; Cristina Mecucci; Giuseppe Saglio; Francesco Lo Coco; Daniela Diverio; Patrick Brown; Fabrizio Pane; Marco Mancini; Maria Paola Martelli; Stefano Pileri; Torsten Haferlach; Claudia Haferlach; Susanne Schnittger
NPM1 mutations and cytoplasmic nucleophosmin are mutually exclusive of recurrent genetic abnormalities: a comparative analysis of 2562 patients with acute myeloid leukemia.
Haematologica 2008;93(3):439-42.
2008: Rania T Awwad; Khanh Do; Holly Stevenson; Sidney W Fu; Francesco Lo Coco; Maura Costello; Cassandra L Campbell; Patricia E Berg
Overexpression of BP1, a homeobox gene, is associated with resistance to all-trans retinoic acid in acute promyelocytic leukemia cells.
Annals of hematology 2008;87(3):195-203.
2008: Francesco Buccisano; Luca Maurillo; Anna Tamburini; Giovanni Del Poeta; Maria Ilaria Del Principe; Emanuele Ammatuna; Maria Irno Consalvo; Selenia Campagna; Licia Ottaviani; Chiara Sarlo; Daniela Renzi; Sabrina Faccia; Daniela Fraboni; Francesco Lo Coco; Sergio Amadori; Adriano Venditti
Evaluation of the prognostic relevance of L-selectin and ICAM1 expression in myelodysplastic syndromes.
European journal of haematology 2008;80(2):107-14.
2007: Francesco Fazi; Serena Racanicchi; Giuseppe Zardo; Linda Starnes; Marco Mancini; Lorena Travaglini; Daniela Diverio; Emanuele Ammatuna; Giuseppe Cimino; Francesco Lo Coco; Francesco Grignani; Clara Nervi
Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein.
Cancer cell 2007;12(5):457-66.
2007: Roberta Riccioni; Mara Senese; Daniela Diverio; Viviana Riti; Sonia Buffolino; Gualtiero Mariani; Alessandra Boe; Michele Cedrone; Francesco Lo Coco; Robin Foà; Cesare Peschle; Ugo Testa
M4 and M5 acute myeloid leukaemias display a high sensitivity to Bortezomib-mediated apoptosis.
British journal of haematology 2007;139(2):194-205.
2007: Massimo Breccia; Giuseppe Cimino; Daniela Diverio; Fabiana Gentilini; Franco Mandelli; Francesco Lo Coco
Sustained molecular remission after low dose gemtuzumab-ozogamicin in elderly patients with advanced acute promyelocytic leukemia.
Haematologica 2007;92(9):1273-4.
2007: Roberta Riccioni; Daniela Diverio; Gualtiero Mariani; Sonia Buffolino; Viviana Riti; ernestina saulle; Eleonora Petrucci; Michele Cedrone; Francesco Lo Coco; Robin Foà; Cesare Peschle; Ugo Testa
Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts.
Stem cells (Dayton, Ohio) 2007;25(8):1862-71.
2007: Francesco Fazi; Giuseppe Zardo; Vania Gelmetti; Lorena Travaglini; Alberto Ciolfi; Luciano Di Croce; Alessandro Rosa; Irene Bozzoni; Francesco Grignani; Francesco Lo Coco; Pier Giuseppe Pelicci; Clara Nervi
Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia.
Blood 2007;109(10):4432-40.
2007: Emanuele Ammatuna; Tiziana Ottone; Serena Zaza; Serena Lavorgna; Rosa Grillo; Paola Curzi; Paola Panetta; Giorgio Federici; Sergio Amadori; Francesco Lo Coco
Diagnostic refinement of chronic myeloproliferative disorders and thrombocytoses of unknown origin by multiple RT-PCR and capillary electrophoresis of BCR-ABL rearrangements and JAK2 (V617F) mutation.
Annals of hematology 2007;86(5):355-61.
2007: Massimo Breccia; Fabiana Gentilini; Anna Guarini; Maria Stefania De Propris; Giuseppe Cimino; Francesco Lo Coco
Haemolytic uremic syndrome during induction therapy in an acute promyelocytic leukemia patient with aberrant phenotype: a possible manifestation of retinoic acid syndrome.
Leukemia & lymphoma 2007;48(4):833-4.
2007: Vincenza Martini; Clara Minotti; Massimo Breccia; Gioia De Angelis; Sonia Buffolino; Montano Mariella; Francesco Lo Coco; Giuseppe Avvisati; Giuseppe Cimino
Prolonged molecular remission in a newly diagnosed acute promyelocytic leukaemia with a severe cardiomyopathy using low-dose gemtuzumab ozogamicin and all-trans retinoic acid.
Annals of hematology 2007;86(4):295-7.
2007: Francesco Lo Coco; Emanuele Ammatuna; Miguel A Sanz
Current treatment of acute promyelocytic leukemia.
Haematologica 2007;92(3):289-91.
2007: Francesco Lo Coco; Emanuele Ammatuna
Front line clinical trials and minimal residual disease monitoring in acute promyelocytic leukemia.
Current topics in microbiology and immunology 2007;313():145-56.
2007: Roberto Latagliata; Ida Carmosino; Massimo Breccia; Antonio Minni; Anna Maria Testi; Nicol Iorio; Francesco Lo Coco; Giuseppe Avvisati; Maria Concetta Petti; Franco Mandelli; Giuseppe Cimino
Late relapses in acute promyelocytic leukaemia.
Acta haematologica 2007;117(2):106-8.
2007: Massimo Breccia; Giuseppe Avvisati; Roberto Latagliata; Ida Carmosino; Anna Guarini; Maria Stefania De Propris; Fabiana Gentilini; Maria Concetta Petti; Giuseppe Cimino; Franco Mandelli; Francesco Lo Coco
Occurrence of thrombotic events in acute promyelocytic leukemia correlates with consistent immunophenotypic and molecular features.
Leukemia 2007;21(1):79-83.
2006: Roberta Riccioni; Alessia Calzolari; Mauro Biffoni; Mara Senese; Viviana Riti; Eleonora Petrucci; Luca Pasquini; Michele Cedrone; Francesco Lo Coco; Daniela Diverio; Robin Foà; Cesare Peschle; Ugo Testa
Podocalyxin is expressed in normal and leukemic monocytes.
Blood cells, molecules & diseases 2006;37(3):218-25.
2006: Ida Casorelli; Elena Tenedini; Enrico Tagliafico; Monica Francesca Blasi; alessandro Giuliani; Marco Crescenzi; Elvira Pelosi; Ugo Testa; Cesare Peschle; Luca Mele; Daniela Diverio; M Breccia; Francesco Lo Coco; S Ferrari; Margherita Bignami
Identification of a molecular signature for leukemic promyelocytes and their normal counterparts: Focus on DNA repair genes.
Leukemia 2006;20(11):1978-88.
2006: Francesco Buccisano; Luca Maurillo; Valter Gattei; Giovanni Del Poeta; Maria Ilaria Del Principe; m christina cox; Paola Panetta; Maria Irno Consalvo; Carla Mazzone; Benedetta Neri; Licia Ottaviani; D Fraboni; Anna Tamburini; Francesco Lo Coco; Sergio Amadori; Adriano Venditti
The kinetics of reduction of minimal residual disease impacts on duration of response and survival of patients with acute myeloid leukemia.
Leukemia 2006;20(10):1783-9.
2006: Sergio Bernardini; Marzia Nuccetelli; Nélida I Noguera; Lorenza Bellincampi; Paolo Lunghi; Antonio Bonati; Koren Mann; Wilson H Miller; Giorgio Federici; Francesco Lo Coco
Role of GSTP1-1 in mediating the effect of As2O3 in the Acute Promyelocytic Leukemia cell line NB4.
Annals of hematology 2006;85(10):681-7.
2006: Brunangelo Falini; Maria Paola Martelli; Niccolò Bolli; Rossella Bonasso; Emanuela Ghia; Maria Teresa Pallotta; Daniela Diverio; Ildo Nicoletti; Roberta Pacini; Alessia Tabarrini; Barbara Verducci Galletti; Roberta Mannucci; Giovanni Roti; Roberto Rosati; Giorgina Specchia; Arcangelo Liso; Enrico Tiacci; Myriam Alcalay; Lucilla Luzi; Sara Volorio; Loris Bernard; Anna Guarini; Sergio Amadori; Franco Mandelli; Fabrizio Pane; Francesco Lo Coco; Giuseppe Saglio; Pier Giuseppe Pelicci; Massimo F Martelli; Cristina Mecucci
Immunohistochemistry predicts nucleophosmin (NPM) mutations in acute myeloid leukemia.
Blood 2006;108(6):1999-2005.
2006: Giuseppe Cimino; Francesco Lo Coco; SUSANNA FENU; Lorena Travaglini; Erica Finolezzi; Marco Mancini; Mauro Nanni; Angela Careddu; Francesco Fazi; Fabrizio Padula; Roberto Fiorini; Maria Antonietta Aloe Spiriti; Maria Concetta Petti; Adriano Venditti; Sergio Amadori; Franco Mandelli; Pier Giuseppe Pelicci; Clara Nervi
Sequential valproic acid/all-trans retinoic acid treatment reprograms differentiation in refractory and high-risk acute myeloid leukemia.
Cancer research 2006;66(17):8903-11.
2006: Maria Ilaria Del Principe; Giovanni Del Poeta; Francesco Buccisano; Luca Maurillo; Adriano Venditti; Antonella Zucchetto; Rita Marini; Pasquale Niscola; Maria Antonietta Irno Consalvo; Carla Mazzone; Licia Ottaviani; Paola Panetta; Antonio Bruno; Riccardo Bomben; Giovanna Suppo; Massimo Degan; Valter Gattei; Paolo De Fabritiis; Maria Cantonetti; Francesco Lo Coco; Domenico Del Principe; Sergio Amadori
Clinical significance of ZAP-70 protein expression in B-cell chronic lymphocytic leukemia.
Blood 2006;108(3):853-61.
2006: Paolo Gorello; Giovanni Cazzaniga; F Alberti; Maria Grazia Dell'Oro; Enrico Gottardi; Giorgina Specchia; Giovanni Roti; Roberto Rosati; Massimo F Martelli; Daniela Diverio; Francesco Lo Coco; Andrea Biondi; Giuseppe Saglio; Cristina Mecucci; Brunangelo Falini
Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations.
Leukemia 2006;20(6):1103-8.
2006: Paolo Lunghi; Antonio Costanzo; Luigi Salvatore; Nélida I Noguera; Laura Mazzera; Antonio Tabilio; Francesco Lo Coco; Massimo Levrero; Antonio Bonati
MEK1 inhibition sensitizes primary acute myelogenous leukemia to arsenic trioxide-induced apoptosis.
Blood 2006;107(11):4549-53.
2006: francesco cavazzini; Antonella Bardi; Elisa Tammiso; Maria Ciccone; Antonella Russo-Rossi; Domenica Divona; Francesco Lo Coco; Jesus Maria Hernandez; Iwona Wlodarska; Anne Hagemeijer; Gianluigi Castoldi; Antonio Cuneo
Validation of an interphase fluorescence in situ hybridization approach for the detection of MLL gene rearrangements and of the MLL/AF9 fusion in acute myeloid leukemia.
Haematologica 2006;91(3):381-5.
2006: Maria José Carnicer; Sergio Bernardini; Lorenza Bellincampi; Nélida I Noguera; Marzia Nuccetelli; Emanuele Ammatuna; Massimo Breccia; Francesco Lo Coco; Giorgio Federici
Role of gamma-glutamyl cysteine synthetase (gamma-GCS) gene expression as marker of drug sensitivity in acute myeloid leukemias.
Clinica chimica acta; international journal of clinical chemistry 2006;365(1-2):342-5.
2006: Brunangelo Falini; Barbara Bigerna; Alessandra Pucciarini; Enrico Tiacci; Cristina Mecucci; Stephan W Morris; Niccolò Bolli; Roberto Rosati; Silva H Hanissian; Z Ma; Y Sun; Emanuela Colombo; D A Arber; Roberta Pacini; Roberta La Starza; B Verducci Galletti; B V Galletti; Arcangelo Liso; Maria Paola Martelli; Daniela Diverio; Pier Giuseppe Pelicci; Francesco Lo Coco; F L Coco; Massimo F Martelli
Aberrant subcellular expression of nucleophosmin and NPM-MLF1 fusion protein in acute myeloid leukaemia carrying t(3;5): a comparison with NPMc+ AML.
Leukemia 2006;20(2):368-71.
2006: Francesco Lo Coco; Emanuele Ammatuna
The biology of acute promyelocytic leukemia and its impact on diagnosis and treatment.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2006;():156-61, 514.
2006: Francesco Lo Coco; Emanuele Ammatuna; Nélida I Noguera
Treatment of acute promyelocytic leukemia with gemtuzumab ozogamicin.
Clinical advances in hematology & oncology : H&O 2006;4(1):57-62, 76-7.
2005: Giovanni Del Poeta; Maria Ilaria Del Principe; Maria Antonietta Irno Consalvo; Luca Maurillo; Francesco Buccisano; Adriano Venditti; Carla Mazzone; Antonio Bruno; Laura Gianní; Giovanni Capelli; Francesco Lo Coco; Maria Cantonetti; Valter Gattei; Sergio Amadori
The addition of rituximab to fludarabine improves clinical outcome in untreated patients with ZAP-70-negative chronic lymphocytic leukemia.
Cancer 2005;104(12):2743-52.
2005: Miguel A Sanz; Martin S Tallman; Francesco Lo Coco
Practice points, consensus, and controversial issues in the management of patients with newly diagnosed acute promyelocytic leukemia.
The oncologist 2005;10(10):806-14.
2005: Emanuele Ammatuna; Nélida I Noguera; Daniela Zangrilli; Paola Curzi; Paola Panetta; Paola Bencivenga; Sergio Amadori; Giorgio Federici; Francesco Lo Coco
Rapid detection of nucleophosmin (NPM1) mutations in acute myeloid leukemia by denaturing HPLC.
Clinical chemistry 2005;51(11):2165-7.
2005: Ugo Testa; Roberta Riccioni; Mauro Biffoni; Daniela Diverio; Francesco Lo Coco; Robin Foà; Cesare Peschle; Arthur E Frankel
Diphtheria toxin fused to variant human interleukin-3 induces cytotoxicity of blasts from patients with acute myeloid leukemia according to the level of interleukin-3 receptor expression.
Blood 2005;106(7):2527-9.
2005: Miguel A Sanz; Pierre Fenaux; Francesco Lo Coco
Arsenic trioxide in the treatment of acute promyelocytic leukemia. A review of current evidence.
Haematologica 2005;90(9):1231-5.
2005: Maria Cristina Rapanotti; Roberta Caruso; Sergio Bernardini; Valentina Coletti; Francesco Lo Coco; Giulio De Rossi
Idiopathic hypereosinophilic syndrome: a case evolving in B-lymphoblastic lymphoma.
Leukemia research 2005;29(8):975-9.
2005: Nélida I Noguera; Emanuele Ammatuna; Daniela Zangrilli; S Lavorgna; Mariadomenica Divona; Francesco Buccisano; Sergio Amadori; Cristina Mecucci; B Falini; Francesco Lo Coco
Simultaneous detection of NPM1 and FLT3-ITD mutations by capillary electrophoresis in acute myeloid leukemia.
Leukemia 2005;19(8):1479-82.
2005: Myriam Alcalay; Enrico Tiacci; Roberta Bergomas; Barbara Bigerna; Elisa Venturini; Simone Minardi; Natalia Meani; Daniela Diverio; Loris Bernard; Laura Tizzoni; Sara Volorio; Lucilla Luzi; Emanuela Colombo; Francesco Lo Coco; Cristina Mecucci; Brunangelo Falini; Pier Giuseppe Pelicci
Acute myeloid leukemia bearing cytoplasmic nucleophosmin (NPMc+ AML) shows a distinct gene expression profile characterized by up-regulation of genes involved in stem-cell maintenance.
Blood 2005;106(3):899-902.
2005: Anna Maria Testi; Andrea Biondi; Francesco Lo Coco; Maria Luisa Moleti; Fiorina Giona; Marco Vignetti; Giuseppe Menna; Franco Locatelli; Andrea Pession; Elena Barisone; Giulio De Rossi; Daniela Diverio; Concetta Micalizzi; Maurizio Aricò; Giuseppe Basso; Robin Foa; Franco Mandelli
GIMEMA-AIEOPAIDA protocol for the treatment of newly diagnosed acute promyelocytic leukemia (APL) in children.
Blood 2005;106(2):447-53.
2005: Chiara Pilatrino; Daniela Cilloni; Emanuela Messa; Alessandro Morotti; Emilia Giugliano; Marisa Pautasso; Ubaldo Familiari; Susanna Cappia; Pier Giuseppe Pelicci; Francesco Lo Coco; Giuseppe Saglio; Angelo Guerrasio
Increase in platelet count in older, poor-risk patients with acute myeloid leukemia or myelodysplastic syndrome treated with valproic acid and all-trans retinoic acid.
Cancer 2005;104(1):101-9.
2005: Miguel A Sanz; Francesco Lo Coco
Standard practice and controversial issues in front-line therapy of acute promyelocytic leukemia.
Haematologica 2005;90(6):840-5.
2005: Roberta Riccioni; Luca Pasquini; Gualtiero Mariani; ernestina saulle; Annalisa Rossini; Daniela Diverio; Elvira Pelosi; Antonella Vitale; Anna Chierichini; Michele Cedrone; Robin Foà; Francesco Lo Coco; Cesare Peschle; Ugo Testa
TRAIL decoy receptors mediate resistance of acute myeloid leukemia cells to TRAIL.
Haematologica 2005;90(5):612-24.
2005: Miguel A Sanz; Martin S Tallman; Francesco Lo Coco
Tricks of the trade for the appropriate management of newly diagnosed acute promyelocytic leukemia.
Blood 2005;105(8):3019-25.
2005: Francesco Fazi; Lorena Travaglini; Daniela Carotti; Franco Palitti; Daniela Diverio; Myriam Alcalay; Suzan McNamara; Wilson H Miller; Francesco Lo Coco; Pier Giuseppe Pelicci; Clara Nervi
Retinoic acid targets DNA-methyltransferases and histone deacetylases during APL blast differentiation in vitro and in vivo.
Oncogene 2005;24(11):1820-30.
2005: Francesco Lo Coco
Additive effects in the induction of apoptosis in leukemic cells by WT1 and BCR-ABL specific siRNA.
Haematologica 2005;90(3):291A.
2005: Elena Belloni; Maurizio Trubia; Patrizia Gasparini; Carla Micucci; Cinzia Tapinassi; Stefano Confalonieri; Paolo Giovanni Nuciforo; Bruno Martino; Francesco Lo Coco; Pier Giuseppe Pelicci; Pier Paolo Di Fiore
8p11 myeloproliferative syndrome with a novel t(7;8) translocation leading to fusion of the FGFR1 and TIF1 genes.
Genes, chromosomes & cancer 2005;42(3):320-5.
2005: Maria Ilaria Del Principe; Giovanni Del Poeta; Adriano Venditti; Francesco Buccisano; Luca Maurillo; Carla Mazzone; Antonio Bruno; Benedetta Neri; Maria Irno Consalvo; Francesco Lo Coco; Sergio Amadori
Apoptosis and immaturity in acute myeloid leukemia.
Hematology (Amsterdam, Netherlands) 2005;10(1):25-34.
2005: Paolo Lunghi; Antonio Tabilio; Francesco Lo Coco; PG Pelicci; P Pelicci; Antonio Bonati
Arsenic trioxide (ATO) and MEK1 inhibition synergize to induce apoptosis in acute promyelocytic leukemia cells.
Leukemia 2005;19(2):234-44.
2005: Brunangelo Falini; Cristina Mecucci; Enrico Tiacci; Myriam Alcalay; Roberto Rosati; Laura Pasqualucci; Roberta La Starza; Daniela Diverio; Emanuela Colombo; Antonella Santucci; Barbara Bigerna; Roberta Pacini; Alessandra Pucciarini; Arcangelo Liso; Marco Vignetti; Paola Fazi; Natalia Meani; Valentina Pettirossi; Giuseppe Saglio; Franco Mandelli; Francesco Lo Coco; Pier Giuseppe Pelicci; Massimo F Martelli
Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype.
The New England journal of medicine 2005;352(3):254-66.
2004: Elena Belloni; Maurizio Trubia; Marco Mancini; Valentina Derme; Mauro Nanni; Idoya Lahortiga; Roberta Riccioni; Stefano Confalonieri; Francesco Lo Coco; Pier Paolo Di Fiore; Pier Giuseppe Pelicci
A new complex rearrangement involving the ETV6, LOC115548, and MN1 genes in a case of acute myeloid leukemia.
Genes, chromosomes & cancer 2004;41(3):272-7.
2004: Enrico Tiacci; Stefano Pileri; Annette Orleth; Roberta Pacini; Alessia Tabarrini; Federica Frenguelli; Arcangelo Liso; Daniela Diverio; Francesco Lo Coco; Brunangelo Falini
PAX5 expression in acute leukemias: higher B-lineage specificity than CD79a and selective association with t(8;21)-acute myelogenous leukemia.
Cancer research 2004;64(20):7399-404.
2004: Francesco Lo Coco; Giuseppe Cimino; Massimo Breccia; Nélida I Noguera; Daniela Diverio; Erica Finolezzi; Enrico Pogliani; Eros Di Bona; Concetta Micalizzi; Mariagrazia Kropp; Adriano Venditti; Agostino Tafuri; Franco Mandelli
Gemtuzumab ozogamicin (Mylotarg) as a single agent for molecularly relapsed acute promyelocytic leukemia.
Blood 2004;104(7):1995-9.
2004: m christina cox; Paola Panetta; Francesco Lo Coco; Giovanni Del Poeta; Adriano Venditti; Luca Maurillo; Maria Ilaria Del Principe; Alessandro Mauriello; Lucia Anemona; Antonio Bruno; Carla Mazzone; Paolo Palombo; Sergio Amadori
Chromosomal aberration of the 11q23 locus in acute leukemia and frequency of MLL gene translocation: results in 378 adult patients.
American journal of clinical pathology 2004;122(2):298-306.
2004: Pascual Bolufer; Dolors Colomer; Maria T Gomez; Joaquín Martínez; Silvia M Gonzalez; Marcos Gonzalez; Josep Nomdedeu; Beatriz Bellosillo; Eva Barragán; Francesco Lo Coco; Daniela Diverio; Lourdes Hermosin; José García-Marco; Maria D De Juan; Francisco Barros; Rafael Romero; Miguel A Sanz
Quantitative assessment of PML-RARa and BCR-ABL by two real-time PCR instruments: multiinstitutional laboratory trial.
Clinical chemistry 2004;50(6):1088-92.
2004: Ida Carmosino; Roberto Latagliata; Giuseppe Avvisati; Massimo Breccia; Erica Finolezzi; Francesco Lo Coco; Maria Concetta Petti
Arsenic trioxide in the treatment of advanced acute promyelocytic leukemia.
Haematologica 2004;89(5):615-7.
2004: Ugo Testa; Roberta Riccioni; Daniela Diverio; Annalisa Rossini; Francesco Lo Coco; Cesare Peschle
Interleukin-3 receptor in acute leukemia.
Leukemia 2004;18(2):219-26.
2004: Idoya Lahortiga; Xabier Agirre; Elena Belloni; Iria Vázquez; María J Larrayoz; Patrizia Gasparini; Francesco Lo Coco; Pier Giuseppe Pelicci; María J Calasanz; María D Odero
Molecular characterization of a t(1;3)(p36;q21) in a patient with MDS. MEL1 is widely expressed in normal tissues, including bone marrow, and it is not overexpressed in the t(1;3) cells.
Oncogene 2004;23(1):311-6.
2004: Massimo Breccia; Daniela Diverio; Nélida I Noguera; Giuseppe Visani; Alessandra Santoro; Franco Locatelli; Daniela Damiani; Filippo Marmont; Marco Vignetti; Maria Concetta Petti; Francesco Lo Coco
Clinico-biological features and outcome of acute promyelocytic leukemia patients with persistent polymerase chain reaction-detectable disease after the AIDA front-line induction and consolidation therapy.
Haematologica 2004;89(1):29-33.
2003: Bruce D Cheson; John M Bennett; Kenneth J Kopecky; Thomas Büchner; Cheryl L Willman; Elihu H Estey; Charles Alan Schiffer; Hartmut Doehner; Martin S Tallman; T Andrew Lister; Francesco Lo Coco; Rein Willemze; Andrea Biondi; Wolfgang Hiddemann; Richard A Larson; Bob Löwenberg; Miguel A Sanz; David R Head; Ryuzo Ohno; Clara D Bloomfield; Francesco LoCocco
Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(24):4642-9.
2003: Francesco Lo Coco; Massimo Breccia; Nélida I Noguera; Wilson H Miller
Diagnostic value of detecting fusion proteins derived from chromosome translocations in acute leukaemia.
Best practice & research. Clinical haematology 2003;16(4):653-70.
2003: Adriano Venditti; Luca Maurillo; Francesco Buccisano; Giovanni Del Poeta; Carla Mazzone; Anna Tamburini; Maria Ilaria Del Principe; Maria Irno Consalvo; Paolo De Fabritiis; Laura Cudillo; Alessandra Picardi; Annibale Franchi; Francesco Lo Coco; Sergio Amadori; F L Coco
Pretransplant minimal residual disease level predicts clinical outcome in patients with acute myeloid leukemia receiving high-dose chemotherapy and autologous stem cell transplantation.
Leukemia 2003;17(11):2178-82.
2003: Francesco Lo Coco; Atelda Romano; Andrea Mengarelli; Daniela Diverio; Anna Paola Iori; Maria Luisa Moleti; Silvia De Santis; Raffaella Cerretti; Franco Mandelli; William Arcese
Allogeneic stem cell transplantation for advanced acute promyelocytic leukemia: results in patients treated in second molecular remission or with molecularly persistent disease.
Leukemia 2003;17(10):1930-3.
2003: Daniela Cilloni; Sonia Carturan; Enrico Gottardi; Francesca Messa; Emanuela Messa; Milena Fava; Daniela Diverio; Angelo Guerrasio; Francesco Lo Coco; Giuseppe Saglio
Down-modulation of the C/EBPalpha transcription factor in core binding factor acute myeloid leukemias.
Blood 2003;102(7):2705-6.
2003: Francesco Lo Coco; Massimo Breccia; Daniela Diverio
The importance of molecular monitoring in acute promyelocytic leukaemia.
Best practice & research. Clinical haematology 2003;16(3):503-20.
2003: Miguel A Sanz; Guillermo Martín; Francesco Lo Coco
Choice of chemotherapy in induction, consolidation and maintenance in acute promyelocytic leukaemia.
Best practice & research. Clinical haematology 2003;16(3):433-51.
2003: Franco Mandelli; Roberto Latagliata; Giuseppe Avvisati; Paola Fazi; Francesco Rodeghiero; Franco Leoni; marco gobbi; Francesco Nobile; Eugenio Gallo; R Fanin; Sergio Amadori; Marco Vignetti; Giuseppe Fioritoni; Felicetto Ferrara; Antonio Peta; Rosario Giustolisi; Giorgio Broccia; Maria Concetta Petti; Francesco Lo Coco
Treatment of elderly patients (> or =60 years) with newly diagnosed acute promyelocytic leukemia. Results of the Italian multicenter group GIMEMA with ATRA and idarubicin (AIDA) protocols.
Leukemia 2003;17(6):1085-90.
2003: Giovanna Maria Pierantoni; Valter Agosti; Monica Fedele; Heather M Bond; Irene Caliendo; Gennaro Chiappetta; Francesco Lo Coco; Fabrizio Pane; Maria Caterina Turco; Giovanni Morrone; Salvatore Venuta; Alfredo Fusco
High-mobility group A1 proteins are overexpressed in human leukaemias.
The Biochemical journal 2003;372(Pt 1):145-50.
2003: Corrado Girmenia; Francesco Lo Coco; Massimo Breccia; Roberto Latagliata; Antonio Spadea; Mariella D'Andrea; Giuseppe Gentile; Alessandra Micozzi; Giuliana Alimena; Pietro Martino; Franco Mandelli
Infectious complications in patients with acute promyelocytic leukaemia treated with the AIDA regimen.
Leukemia 2003;17(5):925-30.
2003: Giovanni Martinelli; Pier Paolo Piccaluga; Francesco Lo Coco
FLT3 inhibition as tailored therapy for acute myeloid leukemia.
Haematologica 2003;88(1):4-8.
2003: Massimo Breccia; Ida Carmosino; Daniela Diverio; Silvia De Santis; Maria Stefania De Propris; Atelda Romano; Maria Concetta Petti; Franco Mandelli; Francesco Lo Coco
Early detection of meningeal localization in acute promyelocytic leukaemia patients with high presenting leucocyte count.
British journal of haematology 2003;120(2):266-70.
2003: Roberta Riccioni; ernestina saulle; Stefania Militi; Nadia Maria Sposi; M Gualtiero; N Mauro; M Mancini; Daniela Diverio; Francesco Lo Coco; Cesare Peschle; Ugo Testa
C-fms expression correlates with monocytic differentiation in PML-RAR alpha+ acute promyelocytic leukemia.
Leukemia 2003;17(1):98-113.
2002: Michele Baccarani; Francesco Lo Coco; Andrea Bacigalupo
Guidelines in hematology.
Haematologica 2002;87(12):1239-40.
2002: Nélida I Noguera; Massimo Breccia; Mariadomenica Divona; Daniela Diverio; V Costa; Silvia De Santis; Giuseppe Avvisati; M B Pinazzi; Maria Concetta Petti; Franco Mandelli; Francesco Lo Coco
Alterations of the FLT3 gene in acute promyelocytic leukemia: association with diagnostic characteristics and analysis of clinical outcome in patients treated with the Italian AIDA protocol.
Leukemia 2002;16(11):2185-9.
2002: Giuseppe Avvisati; Maria Concetta Petti; Francesco Lo Coco; Maria Luce Vegna; Sergio Amadori; Michele Baccarani; Nicola Cantore; Eros Di Bona; Felicetto Ferrara; Giuseppe Fioritoni; Eugenio Gallo; Rosangela Invernizzi; Mario Lazzarino; Vincenzo Liso; Guglielmo Mariani; Francesco Ricciuti; Carmine Selleri; Simona Sica; Dino Veneri; Franco Mandelli
Induction therapy with idarubicin alone significantly influences event-free survival duration in patients with newly diagnosed hypergranular acute promyelocytic leukemia: final results of the GIMEMA randomized study LAP 0389 with 7 years of minimal follow-up.
Blood 2002;100(9):3141-6.
2002: Saverio Minucci; Silvia Monestiroli; Sabrina Giavara; Simona Ronzoni; Francesco Marchesi; Alessandra Insinga; Daniela Diverio; Patrizia Gasparini; Manuela Capillo; Emanuela Colombo; Cristian Matteucci; Francesco Contegno; Francesco Lo Coco; Eugenio Scanziani; Alberto Gobbi; Pier Giuseppe Pelicci
PML-RAR induces promyelocytic leukemias with high efficiency following retroviral gene transfer into purified murine hematopoietic progenitors.
Blood 2002;100(8):2989-95.
2002: Ugo Testa; Roberta Riccioni; Stefania Militi; Eliana M Coccia; Emilia Stellacci; Paola Samoggia; Roberto Latagliata; Gualtiero Mariani; Annalisa Rossini; Angela Battistini; Francesco Lo Coco; Cesare Peschle
Elevated expression of IL-3Ralpha in acute myelogenous leukemia is associated with enhanced blast proliferation, increased cellularity, and poor prognosis.
Blood 2002;100(8):2980-8.
2002: Maria Teresa Voso; Francesco D'Alo'; Rossana Putzulu; Luca Mele; Alessandra Scardocci; Patrizia Chiusolo; Roberto Latagliata; Francesco Lo Coco; Sergio Rutella; Livio Pagano; Stefan Hohaus; Giuseppe Leone
Negative prognostic value of glutathione S-transferase (GSTM1 and GSTT1) deletions in adult acute myeloid leukemia.
Blood 2002;100(8):2703-7.
2002: Francesco Lo Coco; Arthur Zelent; Adi Kimchi; Michael A Carducci; Steven D Gore; Samuel Waxman
Progress in differentiation induction as a treatment for acute promyelocytic leukemia and beyond.
Cancer research 2002;62(19):5618-21.
2002: Daniela Cilloni; Enrico Gottardi; D De Micheli; Anna Serra; Gisella Volpe; Francesca Messa; Giovanna Rege-Cambrin; Angelo Guerrasio; Mariadomenica Divona; Francesco Lo Coco; Giuseppe Saglio
Quantitative assessment of WT1 expression by real time quantitative PCR may be a useful tool for monitoring minimal residual disease in acute leukemia patients.
Leukemia 2002;16(10):2115-21.
2002: Alessandro Pulsoni; Livio Pagano; Francesco Lo Coco; Giuseppe Avvisati; Luca Mele; Eros Di Bona; Rosangela Invernizzi; Franco Leoni; Filippo Marmont; Alfonso Mele; Lorella Melillo; Annamaria Nosari; Enrico Pogliani; Marco Vignetti; Giuseppe Visani; Vittorina Zagonel; Giuseppe Leone; Franco Mandelli
Clinicobiological features and outcome of acute promyelocytic leukemia occurring as a second tumor: the GIMEMA experience.
Blood 2002;100(6):1972-6.
2002: Antonio Cuneo; Renato Bigoni; francesco cavazzini; Antonella Bardi; Maria Grazia Roberti; Paola Agostini; Elisa Tammiso; N Ciccone; Marco Mancini; Mauro Nanni; R De Cuia; Mariadomenica Divona; Roberta La Starza; Barbara Crescenzi; Nicoletta Testoni; Giovanna Rege-Cambrin; Cristina Mecucci; Francesco Lo Coco; Giuseppe Saglio; Gianluigi Castoldi
Incidence and significance of cryptic chromosome aberrations detected by fluorescence in situ hybridization in acute myeloid leukemia with normal karyotype.
Leukemia 2002;16(9):1745-51.
2002: Maria Concetta Petti; Francesco Fazi; Massimo Gentile; Daniela Diverio; Paolo De Fabritiis; Maria Stefania De Propris; Roberto Fiorini; Maria Antonietta Aloe Spiriti; Fabrizio Padula; Pier Giuseppe Pelicci; Clara Nervi; Francesco Lo Coco
Complete remission through blast cell differentiation in PLZF/RARalpha-positive acute promyelocytic leukemia: in vitro and in vivo studies.
Blood 2002;100(3):1065-7.
2002: Adele Giampaolo; Nadia Felli; Daniela Diverio; Ornella Morsilli; Paola Samoggia; M Breccia; Francesco Lo Coco; Cesare Peschle; Ugo Testa
Expression pattern of HOXB6 homeobox gene in myelomonocytic differentiation and acute myeloid leukemia.
Leukemia 2002;16(7):1293-301.
2002: Valeria Ascoli; Francesco Lo Coco
Body cavity lymphoma.
Current opinion in pulmonary medicine 2002;8(4):317-22.
2002: Angelo Guerrasio; Chiara Pilatrino; D De Micheli; Daniela Cilloni; Anna Serra; Enrico Gottardi; A Parziale; Filippo Marmont; Daniela Diverio; Mariadomenica Divona; Francesco Lo Coco; Giuseppe Saglio
Assessment of minimal residual disease (MRD) in CBFbeta/MYH11-positive acute myeloid leukemias by qualitative and quantitative RT-PCR amplification of fusion transcripts.
Leukemia 2002;16(6):1176-81.
2002: Massimo Breccia; Maria Concetta Petti; Anna Maria Testi; Giorgina Specchia; Felicetto Ferrara; Daniela Diverio; Atelda Romano; V Guerrisi; A Greco; Maria Luisa Fiorella; Marco de Vincentiis; Franco Mandelli; Francesco Lo Coco
Ear involvement in acute promyelocytic leukemia at relapse: a disease-associated 'sanctuary'?
Leukemia 2002;16(6):1127-30.
2002: Francesco Lo Coco
Clinical usefulness of arsenic trioxide in the treatment of acute promyelocytic leukemia.
Haematologica 2002;87(5):452-3.
2002: Francesco Lo Coco; Silvia De Santis; Anna Esposito; Mariadomenica Divona; Daniela Diverio
Molecular monitoring of hematologic malignancies: current and future issues.
Seminars in hematology 2002;39(2 Suppl 1):14-7.
2002: Valeria Ascoli; Francesco Lo Coco; Giuseppe Torelli; Daniele Vallisa; Luigi Cavanna; Cesare Bergonzi; Mario Luppi
Human herpesvirus 8-associated primary effusion lymphoma in HIV--patients: a clinicopidemiologic variant resembling classic Kaposi's sarcoma.
Haematologica 2002;87(4):339-43.
2002: Franco Mandelli; Giuseppe Avvisati; Francesco Lo Coco
Advances in the understanding and management of acute promyelocytic leukemia.
Reviews in clinical and experimental hematology 2002;6(1):60-71; discussion 86-7.
2002: Luciano Di Croce; Veronica A Raker; Massimo Corsaro; Francesco Fazi; Mirco Fanelli; Mario Faretta; François Fuks; Francesco Lo Coco; Tony Kouzarides; Clara Nervi; Saverio Minucci; Pier Giuseppe Pelicci
Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor.
Science (New York, N.Y.) 2002;295(5557):1079-82.
2002: Massimo Breccia; Giuseppe Cimino; Giuliana Alimena; Sara De Carolis; Francesco Lo Coco; Franco Mandelli
AIDA treatment for high-risk acute promyelocytic leukemia in a pregnant woman at 21 weeks of gestation.
Haematologica 2002;87(2):ELT12.
2002: Roberto Latagliata; Maria Concetta Petti; SUSANNA FENU; Marco Mancini; Maria Antonietta Aloe Spiriti; Massimo Breccia; Gregorio A Brunetti; Giuseppe Avvisati; Francesco Lo Coco; Franco Mandelli
Therapy-related myelodysplastic syndrome-acute myelogenous leukemia in patients treated for acute promyelocytic leukemia: an emerging problem.
Blood 2002;99(3):822-4.
2001: Giorgina Specchia; Francesco Lo Coco; Marco Vignetti; Giuseppe Avvisati; Paola Fazi; Francesco Albano; Francesco Di Raimondo; Bruno Martino; Felicetto Ferrara; C Selleri; Vincenzo Liso; Franco Mandelli
Extramedullary involvement at relapse in acute promyelocytic leukemia patients treated or not with all-trans retinoic acid: a report by the Gruppo Italiano Malattie Ematologiche dell'Adulto.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(20):4023-8.
2001: Maria Concetta Petti; M B Pinazzi; Daniela Diverio; Atelda Romano; Maria Teresa Petrucci; Silvia De Santis; Giovanna Meloni; Agostino Tafuri; Franco Mandelli; Francesco Lo Coco
Prolonged molecular remission in advanced acute promyelocytic leukaemia after treatment with gemtuzumab ozogamicin (Mylotarg CMA-676).
British journal of haematology 2001;115(1):63-5.
2001: Pascual Bolufer; Francesco Lo Coco; David Grimwade; Eva Barragán; Daniela Diverio; Bruno Cassinat; C Chomienne; Marcos Gonzalez; Dolors Colomer; M T Gomez; Isabel Marugan; José Román; M D Delgado; José García-Marco; Rafael Bornstein; J L Vizmanos; B Martinez; J Jansen; Ana Villegas; J M de Blas; Pablo Cabello; Miguel A Sanz
Variability in the levels of PML-RAR alpha fusion transcripts detected by the laboratories participating in an external quality control program using several reverse transcription polymerase chain reaction protocols.
Haematologica 2001;86(6):570-6.
2001: Saverio Minucci; Clara Nervi; Francesco Lo Coco; Pier Giuseppe Pelicci
Histone deacetylases: a common molecular target for differentiation treatment of acute myeloid leukemias?
Oncogene 2001;20(24):3110-5.
2001: Valeria Ascoli; S Signoretti; Andrea Onetti Muda; Edoardo Pescarmona; Carlo Della Rocca; Francesco Nardi; CM Mastroianni; Roberta Gastaldi; A Pistilli; Gianluca Gaidano; A Carbone; Francesco Lo Coco
Primary effusion lymphoma in HIV-infected patients with multicentric Castleman's disease.
The Journal of pathology 2001;193(2):200-9.
2001: Felicetto Ferrara; Francesco Fazi; A Bianchini; Fabrizio Padula; Vania Gelmetti; Saverio Minucci; Marco Mancini; Pier Giuseppe Pelicci; Francesco Lo Coco; Clara Nervi
Histone deacetylase-targeted treatment restores retinoic acid signaling and differentiation in acute myeloid leukemia.
Cancer research 2001;61(1):2-7.
2001: Giuseppe Avvisati; Francesco Lo Coco; Franco Mandelli
Acute promyelocytic leukemia: clinical and morphologic features and prognostic factors.
Seminars in hematology 2001;38(1):4-12.
2000: J Serrano; Francesco Lo Coco; T Sprovieri; Loredana Elia; Antonella Vitale; Chiara Gregorj; Agostino Tafuri; J Sánchez; J Román; Antonio Torres; Giuseppe Cimino
Myeloperoxidase gene expression in non-infant pro-B acute lymphoblastic leukaemia with or without ALL1/AF4 transcript.
British journal of haematology 2000;111(4):1065-70.
1999: Valeria Ascoli; CC Scalzo; Massimo Andreoni; L Manente; A Pistilli; Francesco Lo Coco
Kaposi's sarcoma following malignant mesothelioma.
Virchows Archiv : an international journal of pathology 1999;435(6):612-5.
1999: Valeria Ascoli; Maria Caterina Sirianni; Ivano Mezzaroma; CM Mastroianni; Vincenzo Vullo; Massimo Andreoni; P Narciso; CC Scalzo; Francesco Nardi; A Pistilli; Francesco Lo Coco
Human herpesvirus-8 in lymphomatous and nonlymphomatous body cavity effusions developing in Kaposi's sarcoma and multicentric Castleman's disease.
Annals of diagnostic pathology 1999;3(6):357-63.
1999: Valeria Ascoli; CC Scalzo; Chiara Danese; K Vacca; A Pistilli; Francesco Lo Coco
Human herpes virus-8 associated primary effusion lymphoma of the pleural cavity in HIV-negative elderly men.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;14(5):1231-4.
1999: Francesco Lo Coco; Daniela Diverio; Giuseppe Avvisati; Maria Concetta Petti; Giovanna Meloni; Enrico Pogliani; Andrea Biondi; G Rossi; C Carlo-Stella; C Selleri; Bruno Martino; Giorgina Specchia; Franco Mandelli
Therapy of molecular relapse in acute promyelocytic leukemia.
Blood 1999;94(7):2225-9.
1999: Francesco Lo Coco; Daniela Diverio; Brunangelo Falini; Andrea Biondi; Clara Nervi; Pier Giuseppe Pelicci
Genetic diagnosis and molecular monitoring in the management of acute promyelocytic leukemia.
Blood 1999;94(1):12-22.
1999: Francesco Lo Coco; Daniela Diverio; Giuseppe Avvisati; Franco Mandelli
Diagnosis, front line treatment and molecular monitoring of acute promyelocytic leukaemia.
Haematologica 1999;84 Suppl EHA-4():72-4.
1998: Francesco Lo Coco; Clara Nervi; Giuseppe Avvisati; Franco Mandelli
Acute promyelocytic leukemia: a curable disease.
Leukemia 1998;12(12):1866-80.
1998: Franco Mandelli; Maria Concetta Petti; Francesco Lo Coco
Therapy of acute myeloid leukemia: towards a patient-oriented, risk-adapted approach.
Haematologica 1998;83(11):1015-23.
1998: cesare guglielmi; Maria Paola Martelli; Daniela Diverio; SUSANNA FENU; Maria Luce Vegna; A Cantù-Rajnoldi; Andrea Biondi; MG Cocito; L Del Vecchio; Antonio Tabilio; Giuseppe Avvisati; Giuseppe Basso; Francesco Lo Coco
Immunophenotype of adult and childhood acute promyelocytic leukaemia: correlation with morphology, type of PML gene breakpoint and clinical outcome. A cooperative Italian study on 196 cases.
British journal of haematology 1998;102(4):1035-41.
1998: Daniela Diverio; V Rossi; Giuseppe Avvisati; Silvia De Santis; A Pistilli; Fabrizio Pane; Giuseppe Saglio; G Martinelli; Maria Concetta Petti; A Santoro; P G Pelicci; Franco Mandelli; Andrea Biondi; Francesco Lo Coco
Early detection of relapse by prospective reverse transcriptase-polymerase chain reaction analysis of the PML/RARalpha fusion gene in patients with acute promyelocytic leukemia enrolled in the GIMEMA-AIEOP multicenter "AIDA" trial. GIMEMA-AIEOP Multicenter "AIDA" Trial.
Blood 1998;92(3):784-9.
1998: Ugo Testa; Francesco Grignani; Paola Samoggia; Cristiana Zanetti; Roberta Riccioni; Francesco Lo Coco; Daniela Diverio; Nadia Felli; C G Passerini; M Grell; Pier Giuseppe Pelicci; Cesare Peschle
The PML/RARalpha fusion protein inhibits tumor necrosis factor-alpha-induced apoptosis in U937 cells and acute promyelocytic leukemia blasts.
The Journal of clinical investigation 1998;101(10):2278-89.
1998: Valeria Ascoli; Francesco Lo Coco; Marco Artini; Massimo Levrero; M Martelli; F Negro
Extranodal lymphomas associated with hepatitis C virus infection.
American journal of clinical pathology 1998;109(5):600-9.
1998: Valeria Ascoli; Francesco Nardi; Caterina Carnovale-Scalzo; S Signoretti; A Pistilli; Francesco Lo Coco
Absence of HHV-8 DNA sequences in malignant mesothelioma.
Molecular pathology : MP 1998;51(2):113-4.
1998: Wenlin Shao; M Fanelli; F F Ferrara; Roberta Riccioni; Angelika Rosenauer; Kelly Davison; WW Lamph; Samuel Waxman; Pier Giuseppe Pelicci; Francesco Lo Coco; G Avvisati; Ugo Testa; Cesare Peschle; Carlo Gambacorti-Passerini; Clara Nervi; Wilson H Miller
Arsenic trioxide as an inducer of apoptosis and loss of PML/RAR alpha protein in acute promyelocytic leukemia cells.
Journal of the National Cancer Institute 1998;90(2):124-33.
1998: Valeria Ascoli; CM Mastroianni; Vincenzo Galati; Maria Caterina Sirianni; A Fruscalzo; A Pistilli; Francesco Lo Coco
Primary effusion lymphoma containing human herpesvirus 8 DNA in two AIDS patients with Kaposi's sarcoma.
Haematologica 1998;83(1):8-12.
1997: Roberto Latagliata; Giuseppe Avvisati; Francesco Lo Coco; Maria Concetta Petti; Daniela Diverio; Antonio Spadea; Paola Fazi; Concetta Torromeo; Massimo Breccia; F Malagnino; Franco Mandelli
The role of all-trans-retinoic acid (ATRA) treatment in newly-diagnosed acute promyelocytic leukemia patients aged > 60 years.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1997;8(12):1273-5.
1997: Brunangelo Falini; L Flenghi; Marta Fagioli; Francesco Lo Coco; I Cordone; Daniela Diverio; Laura Pasqualucci; Andrea Biondi; Daniela Riganelli; Annette Orleth; Arcangelo Liso; Massimo F Martelli; Pier Giuseppe Pelicci; Stefano Pileri
Immunocytochemical diagnosis of acute promyelocytic leukemia (M3) with the monoclonal antibody PG-M3 (anti-PML).
Blood 1997;90(10):4046-53.
1997: Gianluca Gaidano; C Pastore; Valeria Santini; J Nomdedeu; B Gamberi; Daniela Capello; F Vischia; Luigi Resegotti; U Mazza; Pierluigi Rossi Ferrini; Francesco Lo Coco; Giuseppe Saglio
Genetic lesions associated with blastic transformation of polycythemia vera and essential thrombocythemia.
Genes, chromosomes & cancer 1997;19(4):250-5.
1997: Giovanna Meloni; Daniela Diverio; Marco Vignetti; Giuseppe Avvisati; Saveria Capria; Maria Concetta Petti; Franco Mandelli; Francesco Lo Coco
Autologous bone marrow transplantation for acute promyelocytic leukemia in second remission: prognostic relevance of pretransplant minimal residual disease assessment by reverse-transcription polymerase chain reaction of the PML/RAR alpha fusion gene.
Blood 1997;90(3):1321-5.
1997: L Benedetti; A A Levin; bianca maria scicchitano; Francesco Grignani; G Allenby; Daniela Diverio; Francesco Lo Coco; Giuseppe Avvisati; Martin Ruthardt; Sergio Adamo; Pier Giuseppe Pelicci; Clara Nervi
Characterization of the retinoid binding properties of the major fusion products present in acute promyelocytic leukemia cells.
Blood 1997;90(3):1175-85.
1997: Franco Mandelli; Daniela Diverio; Giuseppe Avvisati; A Luciano; Tiziano Barbui; C Bernasconi; Giorgio Broccia; Raffaella Cerri; Michele Falda; Giuseppe Fioritoni; Franco Leoni; Vincenzo Liso; Maria Concetta Petti; Francesco Rodeghiero; Giuseppe Saglio; Maria Luce Vegna; Giuseppe Visani; Ulrich Jehn; Rein Willemze; Petra Muus; Pier Giuseppe Pelicci; Andrea Biondi; Francesco Lo Coco
Molecular remission in PML/RAR alpha-positive acute promyelocytic leukemia by combined all-trans retinoic acid and idarubicin (AIDA) therapy. Gruppo Italiano-Malattie Ematologiche Maligne dell'Adulto and Associazione Italiana di Ematologia ed Oncologia Pediatrica Cooperative Groups.
Blood 1997;90(3):1014-21.
1997: Giuseppe Cimino; Maria Cristina Rapanotti; Andrea Biondi; Loredana Elia; Francesco Lo Coco; C Price; V Rossi; A Rivolta; E Canaani; C M Croce; Franco Mandelli; M Greaves
Infant acute leukemias show the same biased distribution of ALL1 gene breaks as topoisomerase II related secondary acute leukemias.
Cancer research 1997;57(14):2879-83.
1997: Francesco Lo Coco; Simona Pisegna; Daniela Diverio
The AML1 gene: a transcription factor involved in the pathogenesis of myeloid and lymphoid leukemias.
Haematologica 1997;82(3):364-70.
1997: Giuseppe Cimino; C Lanza; Loredana Elia; Francesco Lo Coco; Gianluca Gaidano; Andrea Biondi; C Pastore; A Serra; E Canaani; C M Croce; Franco Mandelli; Giuseppe Saglio
Multigenetic lesions in infant acute leukaemias: correlations with ALL-1 gene status.
British journal of haematology 1997;96(2):308-13.
1997: Valeria Ascoli; Francesco Lo Coco; Marco Artini; Massimo Levrero; A Fruscalzo; Cristina Mecucci
Primary effusion Burkitt's lymphoma with t(8;22) in a patient with hepatitis C virus-related cirrhosis.
Human pathology 1997;28(1):101-4.
1996: Giuseppe Avvisati; Francesco Lo Coco; Daniela Diverio; Michele Falda; F Ferrara; Mario Lazzarino; D Russo; Maria Concetta Petti; Franco Mandelli
AIDA (all-trans retinoic acid + idarubicin) in newly diagnosed acute promyelocytic leukemia: a Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto (GIMEMA) pilot study.
Blood 1996;88(4):1390-8.
1996: Daniela Diverio; Roberta Riccioni; A Pistilli; Sonia Buffolino; Giuseppe Avvisati; Franco Mandelli; Francesco Lo Coco
Improved rapid detection of the PML/RARalpha fusion gene in acute promyelocytic leukemia.
Leukemia 1996;10(7):1214-6.
1996: L Benedetti; Francesco Grignani; bianca maria scicchitano; A M Jetten; Daniela Diverio; Francesco Lo Coco; Giuseppe Avvisati; Carlo Gambacorti-Passerini; Sergio Adamo; A A Levin; Pier Giuseppe Pelicci; Clara Nervi
Retinoid-induced differentiation of acute promyelocytic leukemia involves PML-RARalpha-mediated increase of type II transglutaminase.
Blood 1996;87(5):1939-50.
1996: Giuseppe Cimino; Loredana Elia; A Rivolta; Maria Cristina Rapanotti; V Rossi; Giuliana Alimena; Luciana Annino; E Canaani; Francesco Lo Coco; Andrea Biondi
Clinical relevance of residual disease monitoring by polymerase chain reaction in patients with ALL-1/AF-4 positive-acute lymphoblastic leukaemia.
British journal of haematology 1996;92(3):659-64.
1996: Brunangelo Falini; B Bigerna; Laura Pasqualucci; M Fizzotti; Massimo F Martelli; S Pileri; A Pinto; Antonino Carbone; S Venturi; R Pacini; Giorgio Cattoretti; E Pescarmona; Francesco Lo Coco; Pier Giuseppe Pelicci; I Anagnastopoulos; Riccardo Dalla-Favera; L Flenghi
Distinctive expression pattern of the BCL-6 protein in nodular lymphocyte predominance Hodgkin's disease.
Blood 1996;87(2):465-71.
1996: C Lanza; Gianluca Gaidano; Giuseppe Cimino; C Pastore; J Nomdedeu; Gisella Volpe; C Vivenza; Guido Parvis; U Mazza; Giuseppe Basso; Enrico Madon; Francesco Lo Coco; Giuseppe Saglio
Distribution of TP53 mutations among acute leukemias with MLL rearrangements.
Genes, chromosomes & cancer 1996;15(1):48-53.
1996: Riccardo Dalla-Favera; B H Ye; Giorgio Cattoretti; Francesco Lo Coco; Chung-Che Chang; J Zhang; Anna Migliazza; K Cechova; Huifeng Niu; Seeta Chaganti; Weiyi Chen; Diane C Louie; Kenneth Offit; Raju S K Chaganti
BCL-6 in diffuse large-cell lymphomas.
Important advances in oncology 1996;():139-48.
1995: Kenneth Offit; Diane C Louie; NZ Parsa; P Roy; Denis Leung; Francesco Lo Coco; Andrew D Zelenetz; Riccardo Dalla-Favera; Raju S K Chaganti
BCL6 gene rearrangement and other cytogenetic abnormalities in diffuse large cell lymphoma.
Leukemia & lymphoma 1995;20(1-2):85-9.
1995: Francesco Lo Coco; G Saglio
Single or multistep origin of hemopoietic tumors: the contribution of clonality studies.
Leukemia 1995;9(9):1586-9.
1995: Giuliana Alimena; M Cedrone; M Nanni; M R De Cuia; Francesco Lo Coco; V De Sanctis; Giuseppe Cimino; Marco Mancini
Acute leukemia presenting a variant Ph chromosome with p190 expression, dup 3q and -7, developed after malignant lymphoma treated with alkylating agents and topoisomerase II inhibitors.
Leukemia 1995;9(9):1483-6.
1995: Edoardo Pescarmona; Francesco Lo Coco; Alberto Pacchiarotti; Maria Cristina Rapanotti; Giuseppe Cimino; B Di Paolo; Carlo Davide Baroni
Analysis of the BCL-6 gene configuration in diffuse B-cell non-Hodgkin's lymphomas and Hodgkin's disease.
The Journal of pathology 1995;177(1):21-5.
1995: L Flenghi; B H Ye; M Fizzotti; B Bigerna; Giorgio Cattoretti; S Venturi; R Pacini; S Pileri; Francesco Lo Coco; E Pescarmona
A specific monoclonal antibody (PG-B6) detects expression of the BCL-6 protein in germinal center B cells.
The American journal of pathology 1995;147(2):405-11.
1995: Francesco Lo Coco; Robin Foa
Diagnostic and prognostic advances in the immunophenotypic and genetic characterization of acute leukaemia.
European journal of haematology 1995;55(1):1-9.
1995: Angelo Guerrasio; C Rosso; giovanni martinelli; Francesco Lo Coco; M Pampinella; A Santoro; C Lanza; B Allione; Luigi Resegotti; Giuseppe Saglio
Polyclonal haemopoieses associated with long-term persistence of the AML1-ETO transcript in patients with FAB M2 acute myeloid leukaemia in continous clinical remission.
British journal of haematology 1995;90(2):364-8.
1995: C Lanza; Gianluca Gaidano; Giuseppe Cimino; Francesco Lo Coco; Giuseppe Basso; L Sainati; C Pastore; J Nomdedeu; Gisella Volpe; Guido Parvis
p53 gene inactivation in acute lymphoblastic leukemia of B cell lineage associates with chromosomal breakpoints at 11q23 and 8q24.
Leukemia 1995;9(6):955-9.
1995: M Fizzotti; Giuseppe Cimino; S Pisegna; Giuliana Alimena; C Quartarone; Franco Mandelli; Pier Giuseppe Pelicci; Francesco Lo Coco
Detection of homozygous deletions of the cyclin-dependent kinase 4 inhibitor (p16) gene in acute lymphoblastic leukemia and association with adverse prognostic features.
Blood 1995;85(10):2685-90.
1995: Giuseppe Cimino; Maria Cristina Rapanotti; A Rivolta; Francesco Lo Coco; E D'Arcangelo; Roberto Rondelli; Giuseppe Basso; E Barisone; C Rosanda; T Santostasi
Prognostic relevance of ALL-1 gene rearrangement in infant acute leukemias.
Leukemia 1995;9(3):391-5.
1995: Daniela Diverio; Roberta Riccioni; Franco Mandelli; Francesco Lo Coco
The PML/RAR alpha fusion gene in the diagnosis and monitoring of acute promyelocytic leukemia.
Haematologica 1995;80(2):155-60.
1995: B H Ye; Francesco Lo Coco; Chung-Che Chang; J Zhang; Anna Migliazza; K Cechova; Daniel M Knowles; Kenneth Offit; Raju S K Chaganti; Riccardo Dalla-Favera
Alterations of the BCL-6 gene in diffuse large-cell lymphoma.
Current topics in microbiology and immunology 1995;194():101-8.
1994: Gianluca Gaidano; Francesco Lo Coco; B H Ye; D Shibata; Alexandra M Levine; Daniel M Knowles; Riccardo Dalla-Favera
Rearrangements of the BCL-6 gene in acquired immunodeficiency syndrome-associated non-Hodgkin's lymphoma: association with diffuse large-cell subtype.
Blood 1994;84(2):397-402.
1994: Kenneth Offit; Francesco Lo Coco; Diane C Louie; NZ Parsa; Denis Leung; Carol S Portlock; B H Ye; F Lista; Daniel A Filippa; A Rosenbaum
Rearrangement of the bcl-6 gene as a prognostic marker in diffuse large-cell lymphoma.
The New England journal of medicine 1994;331(2):74-80.
1994: Daniela Diverio; Pier Paolo Pandolfi; V Rossi; Andrea Biondi; Pier Giuseppe Pelicci; Francesco Lo Coco
Monitoring of treatment outcome in acute promyelocytic leukemia by RT-PCR.
Leukemia 1994;8(7):1105-7.
1994: Angelo Guerrasio; Giuseppe Saglio; C Rosso; Alda Alfarano; Clara Camaschella; Francesco Lo Coco; A Biondi; A Rambaldi; S Nicolis; Sergio Ottolenghi
Expression of GATA-1 mRNA in human myeloid leukemic cells.
Leukemia 1994;8(6):1034-8.
1994: Francesco Lo Coco; F D'Adamo; Daniela Diverio; Pier Giuseppe Pelicci; G Saglio
Polyclonal hemopoiesis in leukemia patients following molecularly documented remission.
Leukemia 1994;8 Suppl 1():S137-9.
1994: Luciana Annino; A Ferrari; M Cedrone; Fiorina Giona; Francesco Lo Coco; Giovanna Meloni; William Arcese; Franco Mandelli
Adult Philadelphia-chromosome-positive acute lymphoblastic leukemia: experience of treatments during a ten-year period.
Leukemia 1994;8(4):664-7.
1994: Francesco Lo Coco; B H Ye; F Lista; Paolo Corradini; Kenneth Offit; Daniel M Knowles; Raju S K Chaganti; Riccardo Dalla-Favera
Rearrangements of the BCL6 gene in diffuse large cell non-Hodgkin's lymphoma.
Blood 1994;83(7):1757-9.
1994: Anna Marina Liberati; Emilio Donti; C Rosso; Francesco Lo Coco; F Dore; S Pardini; S Cocco; M Addis; G Saglio
Repeated PCR in CML during IFN-alpha therapy.
European journal of haematology 1994;52(3):152-5.
1994: Francesco Lo Coco; Pier Giuseppe Pelicci; Andrea Biondi
Clinical relevance of the PML/RAR-a gene rearrangement in acute promyelocytic leukaemia.
Leukemia & lymphoma 1994;12(5-6):327-32.
1994: Francesco Grignani; Marta Fagioli; Myriam Alcalay; L Longo; Pier Paolo Pandolfi; Emilio Donti; Andrea Biondi; Francesco Lo Coco; F Grignani; Pier Giuseppe Pelicci
Acute promyelocytic leukemia: from genetics to treatment.
Blood 1994;83(1):10-25.
1994: Riccardo Dalla-Favera; B H Ye; Francesco Lo Coco; Gianluca Gaidano; F Lista; Daniel M Knowles; Diane C Louie; Kenneth Offit; Raju S K Chaganti
Identification of genetic lesions associated with diffuse large-cell lymphoma.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1994;5 Suppl 1():55-60.
1994: Daniela Diverio; Pier Paolo Pandolfi; V Rossi; Andrea Biondi; Pier Giuseppe Pelicci; Francesco Lo Coco
Monitoring of treatment outcome in acute promyelocytic leukemia by RT-PCR.
Leukemia 1994;8 Suppl 2():S63-5.
1994: Francesco Lo Coco; Angelo Guerrasio; Daniela Diverio; Franco Mandelli; G Saglio
Clonality studies in CML patients treated by IFN and/or autologous bone marrow transplantation.
Bone marrow transplantation 1994;14 Suppl 3():S21-4.
1994: Riccardo Dalla-Favera; B H Ye; Francesco Lo Coco; Chung-Che Chang; K Cechova; J Zhang; Anna Migliazza; W Mellado; Huifeng Niu; Raju S K Chaganti
BCL-6 and the molecular pathogenesis of B-cell lymphoma.
Cold Spring Harbor symposia on quantitative biology 1994;59():117-23.
1993: Daniela Diverio; Pier Paolo Pandolfi; Andrea Biondi; Giuseppe Avvisati; Maria Concetta Petti; Franco Mandelli; Giuliana Pelicci; Francesco Lo Coco
Absence of reverse transcription-polymerase chain reaction detectable residual disease in patients with acute promyelocytic leukemia in long-term remission.
Blood 1993;82(12):3556-9.
1993: Enrico Montefusco; Francesco Lo Coco; Vito Lelio Burgio; B Rondinelli; G Di Giorgio; Marco Mancini; Daniela Diverio; A Andriani; Giuseppe Avvisati; Giuliana Alimena
Occurrence of a Ki-1-positive anaplastic large-cell lymphoma in a patient with Ph' positive chronic myelogenous leukemia successfully treated by alpha-interferon.
Leukemia 1993;7(11):1896-9.
1993: L Longo; D Trecca; Andrea Biondi; Francesco Lo Coco; Francesco Grignani; A T Maiolo; Pier Giuseppe Pelicci; Antonino Neri
Frequency of RAS and p53 mutations in acute promyelocytic leukemias.
Leukemia & lymphoma 1993;11(5-6):405-10.
1993: B H Ye; F Lista; Francesco Lo Coco; Daniel M Knowles; Kenneth Offit; Raju S K Chaganti; Riccardo Dalla-Favera
Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma.
Science (New York, N.Y.) 1993;262(5134):747-50.
1993: Francesco Lo Coco; Gianluca Gaidano; Diane C Louie; Kenneth Offit; Raju S K Chaganti; Riccardo Dalla-Favera
p53 mutations are associated with histologic transformation of follicular lymphoma.
Blood 1993;82(8):2289-95.
1993: Francesco Lo Coco; Franco Mandelli; Massimo Breccia; Luciana Annino; cesare guglielmi; Maria Concetta Petti; Anna Maria Testi; Giuliana Alimena; C M Croce; E Canaani
Southern blot analysis of ALL-1 rearrangements at chromosome 11q23 in acute leukemia.
Cancer research 1993;53(16):3800-3.
1993: Giulio De Rossi; Francesca Romana Mauro; Francesco Lo Coco; R Caruso; P Niscola; D Pasqualetti; Franco Mandelli
CD5 negative lymphocytosis mimicking typical B-chronic lymphocytic leukaemia. Description of 26 cases.
Nouvelle revue française d'hématologie 1993;35(4):451-5.
1993: Francesco Lo Coco; Pier Giuseppe Pelicci; F D'Adamo; Daniela Diverio; Giuliana Alimena; Enrico Montefusco; William Arcese; Giuseppe Avvisati; Lidia De Felice; Giovanna Meloni
Polyclonal hematopoietic reconstitution in leukemia patients at remission after suppression of specific gene rearrangements.
Blood 1993;82(2):606-12.
1993: Giuseppe Cimino; Francesco Lo Coco; Andrea Biondi; Loredana Elia; A Luciano; C M Croce; G Masera; Franco Mandelli; E Canaani
ALL-1 gene at chromosome 11q23 is consistently altered in acute leukemia of early infancy.
Blood 1993;82(2):544-6.
1993: Giulio De Rossi; Carlo E Grossi; R Foà; A Tabilio; L Vègna; Francesco Lo Coco; Luciana Annino; Andrea Camera; N Cascavilla; Stefania Ciolli
Immunophenotype of acute lymphoblastic leukemia cells: the experience of the Italian Cooperative Group (Gimema).
Leukemia & lymphoma 1993;9(3):221-8.
1993: Andrea Biondi; Alessandro Rambaldi; Pier Paolo Pandolfi; Myriam Alcalay; L Longo; V Rossi; Giovanni Giudici; Francesco Lo Coco; Pier Giuseppe Pelicci
Molecular genetics of the t(15;17) translocation in acute promyelocytic leukemia.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1993;131():345-59.
1993: Giuliana Alimena; Giovanna Meloni; M R de Cuia; M B Rondinelli; Francesco Lo Coco; Enrico Montefusco; Marco Mancini; R Pinto; M Nanni; M Cedrone
Management of chronic myeloid leukemia in chronic phase with autologous stem cell transplantation and alpha-2 interferon: cytogenetic and clinical results.
Leukemia & lymphoma 1993;11 Suppl 1():281-91.
1992: Francesco Lo Coco; Daniela Diverio; Pier Paolo Pandolfi; Andrea Biondi; V Rossi; Giuseppe Avvisati; Alessandro Rambaldi; William Arcese; Maria Concetta Petti; Giovanna Meloni
Molecular evaluation of residual disease as a predictor of relapse in acute promyelocytic leukaemia.
Lancet 1992;340(8833):1437-8.
1992: Andrea Biondi; Alessandro Rambaldi; Pier Paolo Pandolfi; V Rossi; Giovanni Giudici; Myriam Alcalay; Francesco Lo Coco; Daniela Diverio; E M Pogliani; E M Lanzi
Molecular monitoring of the myl/retinoic acid receptor-alpha fusion gene in acute promyelocytic leukemia by polymerase chain reaction.
Blood 1992;80(2):492-7.
1992: Enrico Montefusco; Giuliana Alimena; Francesco Lo Coco; M R De Cuia; Y Z Wang; M A Aloe Spiriti; F Mancini; M Cedrone; Marco Mancini; Franco Mandelli
Ph-negative and bcr-negative atypical chronic myelogenous leukemia: biological features and clinical outcome.
Annals of hematology 1992;65(1):17-21.
1992: Daniela Diverio; Francesco Lo Coco; F D'Adamo; Andrea Biondi; Marta Fagioli; Francesco Grignani; Alessandro Rambaldi; V Rossi; Giuseppe Avvisati; Maria Concetta Petti
Identification of DNA rearrangements at the retinoic acid receptor-alpha (RAR-alpha) locus in all patients with acute promyelocytic leukemia (APL) and mapping of APL breakpoints within the RAR-alpha second intron. Italian Cooperative Study Group "GIMEMA".
Blood 1992;79(12):3331-6.
1992: Myriam Alcalay; D Zangrilli; Marta Fagioli; Pier Paolo Pandolfi; Andrea Mencarelli; Francesco Lo Coco; Andrea Biondi; Francesco Grignani; Pier Giuseppe Pelicci
Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemia.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(11):4840-4.
1992: Pier Paolo Pandolfi; Myriam Alcalay; Marta Fagioli; D Zangrilli; Andrea Mencarelli; Daniela Diverio; Andrea Biondi; Francesco Lo Coco; Alessandro Rambaldi; Francesco Grignani
Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic leukaemia.
The EMBO journal 1992;11(4):1397-407.
1992: Francesco Lo Coco; Daniela Diverio; F D'Adamo; Giuseppe Avvisati; Giuliana Alimena; M Nanni; Myriam Alcalay; Pier Paolo Pandolfi; Pier Giuseppe Pelicci
PML/RAR-alpha rearrangement in acute promyelocytic leukaemias apparently lacking the t(15;17) translocation.
European journal of haematology 1992;48(3):173-6.
1991: G Saglio; Angelo Guerrasio; C Rosso; Francesco Lo Coco; M Frontani; L Annino; Franco Mandelli
Detection of Ph1-positive acute lymphoblastic leukaemia by PCR. GIMEMA Cooperative Study Group.
Lancet 1991;338(8772):958.
1991: Francesco Lo Coco; Giuseppe Avvisati; Daniela Diverio; Andrea Biondi; Pier Paolo Pandolfi; Myriam Alcalay; Giulio De Rossi; Maria Concetta Petti; A Cantù-Rajnoldi; D Pasqualetti
Rearrangements of the RAR-alpha gene in acute promyelocytic leukaemia: correlations with morphology and immunophenotype.
British journal of haematology 1991;78(4):494-9.
1991: P F di Celle; Antonino Carbone; Francesco Lo Coco; Angelo Guerrasio; Daniela Diverio; C Rosso; M Lopez; Giuseppe Saglio; R Foà
Identical utilization of T-cell receptor gene regions in B-lymphoid blast crisis of chronic myeloid leukemia and B-precursor acute lymphoblastic leukemia.
Leukemia 1991;5(5):366-72.
1991: Francesco Lo Coco
Hybrid phenotypes and lineage promiscuity in acute leukemia.
Haematologica 1991;76(3):215-25.
1991: Francesco Lo Coco; Giuseppe Avvisati; Daniela Diverio; Maria Concetta Petti; Myriam Alcalay; Pier Paolo Pandolfi; D Zangrilli; Andrea Biondi; Alessandro Rambaldi; Maria Luisa Moleti
Molecular evaluation of response to all-trans-retinoic acid therapy in patients with acute promyelocytic leukemia.
Blood 1991;77(8):1657-9.
1991: Andrea Biondi; Alessandro Rambaldi; Myriam Alcalay; Pier Paolo Pandolfi; Francesco Lo Coco; Daniela Diverio; V Rossi; Andrea Mencarelli; L Longo; D Zangrilli
RAR-alpha gene rearrangements as a genetic marker for diagnosis and monitoring in acute promyelocytic leukemia.
Blood 1991;77(7):1418-22.
1991: Giuseppe Cimino; G Papa; Sante Tura; P Mazza; P L Rossi Ferrini; Alberto Bosi; Sergio Amadori; Francesco Lo Coco; E D'Arcangelo; Diana Giannarelli
Second primary cancer following Hodgkin's disease: updated results of an Italian multicentric study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1991;9(3):432-7.
1991: Francesco Lo Coco; Daniela Diverio; M Frontani; Y Z Wang; Enrico Montefusco; Paolo De Fabritiis; William Arcese; Giulio De Rossi; Franco Mandelli
Chronic myeloid leukaemia lymphoid blast crisis. Relevance of molecular analysis at the bcr and immunoglobulin heavy chain gene level in monitoring response to therapy and residual disease.
European journal of haematology 1991;46(3):172-6.
1991: Myriam Alcalay; D Zangrilli; Pier Paolo Pandolfi; L Longo; Andrea Mencarelli; A Giacomucci; M Rocchi; Andrea Biondi; Alessandro Rambaldi; Francesco Lo Coco
Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(5):1977-81.
1991: William Arcese; Francesca Romana Mauro; Maria Screnci; Giuliana Alimena; Francesco Lo Coco; Anna Paola Iori; M R de Cuia; Paola Fazi; Enrico Montefusco; Franco Mandelli
Interferon therapy for Ph1-positive chronic myelogenous leukaemia patients relapsing after T-cell depleted allogeneic bone marrow transplantation.
European journal of cancer (Oxford, England : 1990) 1991;27 Suppl 4():S28-30.
1990: L Longo; Pier Paolo Pandolfi; Andrea Biondi; Alessandro Rambaldi; Andrea Mencarelli; Francesco Lo Coco; Daniela Diverio; Luigi Pegoraro; G Avanzi; Antonio Tabilio
Rearrangements and aberrant expression of the retinoic acid receptor alpha gene in acute promyelocytic leukemias.
The Journal of experimental medicine 1990;172(6):1571-5.
1990: Francesco Lo Coco; Franco Mandelli; Daniela Diverio; Giuliana Alimena; Paolo De Fabritiis; Giovanna Meloni; M Cedrone; M Frontani; Angelo Guerrasio; G Saglio
Therapy-induced Ph1 suppression in chronic myeloid leukemia: molecular and cytogenetic studies in patients treated with alpha-2b IFN, high-dose chemotherapy and autologous stem cell infusion.
Bone marrow transplantation 1990;6(4):253-8.
1990: Paolo De Fabritiis; A Sandrelli; Giovanna Meloni; Giuliana Alimena; Enrico Montefusco; Francesco Lo Coco; Lidia De Felice; Franco Mandelli
Prolonged suppression of myeloid progenitor cell numbers after stopping interferon treatment for CML may necessitate delay in harvesting marrow cells for autografting.
Bone marrow transplantation 1990;6(4):247-51.
1990: Enrico Montefusco; Francesca Romana Mauro; Francesco Lo Coco; B Rondinelli; William Arcese; A Tabilio; Bruno Monarca; Giuliana Alimena; Franco Mandelli
Long-term remission of T-lymphoid extramedullary blast crisis of chronic myelogenous leukemia following allogeneic bone marrow transplantation.
Haematologica 1990;75(4):391-3.
1990: William Arcese; Francesca Romana Mauro; Giuliana Alimena; Francesco Lo Coco; M R De Cuia; Maria Screnci; Anna Paola Iori; Enrico Montefusco; Franco Mandelli
Interferon therapy for Ph1 positive CML patients relapsing after T cell-depleted allogeneic bone marrow transplantation.
Bone marrow transplantation 1990;5(5):309-15.
1990: R Leone; Francesco Lo Coco; Giulio De Rossi; Daniela Diverio; M Frontani; Antonio Spadea; Anna Maria Testi; Iole Cordone; Franco Mandelli
Immunoglobulin heavy chain and T-cell receptor beta chain gene rearrangements in acute non lymphoid leukemia.
Haematologica 1990;75(2):125-8.
1990: William Arcese; Francesca Romana Mauro; Maria Screnci; Giuliana Alimena; Anna Paola Iori; M R De Cuia; Francesco Lo Coco; Enrico Montefusco; Paola Fazi; Franco Mandelli
Alpha-2b-interferon as single therapy for patients with chronic myeloid leukemia relapsing after T-cell depleted allogeneic bone marrow transplantation.
European journal of haematology. Supplementum 1990;52():36-9.
1989: Giuseppe Saglio; Alfonso Zaccaria; A Tassinari; G Rosti; Francesco Lo Coco; Daniela Diverio; G Rege Cambrin; P Scaravaglio; C Rosso; Angelo Guerrasio
Molecular biology to check patients treated for CML.
Bone marrow transplantation 1989;4 Suppl 4():98-100.
1989: Giovanna Meloni; Paolo De Fabritiis; Giuliana Alimena; F Malagnino; Enrico Montefusco; A Sandrelli; R Pinto; Marco Vignetti; Francesco Lo Coco; Franco Mandelli
Autologous bone marrow or peripheral blood stem cell transplantation for patients with chronic myelogenous leukaemia in chronic phase.
Bone marrow transplantation 1989;4 Suppl 4():92-4.
1989: Francesco Lo Coco; Giulio De Rossi; D Pasqualetti; M Lopez; Daniela Diverio; Roberto Latagliata; SUSANNA FENU; Franco Mandelli
CD7 positive acute myeloid leukaemia: a subtype associated with cell immaturity.
British journal of haematology 1989;73(4):480-5.
1989: Francesco Lo Coco; G Saglio; Paolo De Fabritiis; Daniela Diverio; Angelo Guerrasio; C Rosso; Giovanna Meloni; Marco Mancini; Franco Mandelli
Molecular evidence of transient complete remission after autografting in Ph-/bcr rearranged chronic myelogenous leukaemia.
British journal of haematology 1989;72(2):285-6.
1989: Francesco Lo Coco; D Pasqualetti; M Lopez; E Panzini; A Gentile; Roberto Latagliata; Bruno Monarca; Giulio De Rossi
Immunophenotyping of acute myeloid leukaemia: relevance of analysing different lineage-associated markers.
Blut 1989;58(5):235-40.
1989: Francesco Lo Coco; M Lopez; D Pasqualetti; Enrico Montefusco; Arturo Cafolla; Bruno Monarca; Cecilia Sgadari; Giulio De Rossi
Terminal transferase positive acute myeloid leukemia: immunophenotypic characterization and response to induction therapy.
Hematological oncology 1989;7(2):167-74.
1989: Francesco Lo Coco; P Francia di Celle; G Alimena; G De Rossi; R Gastaldi; Giulia Casorati; Giuseppe Saglio; Robin Foa
Acute lymphoblastic leukemia with the 4;11 translocation exhibiting early T cell features.
Leukemia 1989;3(1):79-82.
1989: Francesco Lo Coco; Giuseppe Basso; P F di Celle; A Tassinari; D Pasqualetti; M R De Cuia; Maria Caterina Putti; Giovanni Del Poeta; Carola Ponzetto; Giuseppe Saglio
Molecular characterization of Ph' + hybrid acute leukemia.
Leukemia research 1989;13(12):1061-7.
1989: Robin Foa; Nicola Migone; P Francia di Celle; Maria Teresa Fierro; A Tassinari; Francesco Lo Coco; Giulia Casorati; F Gavosto
Ontogeny, gene rearrangements and immunophenotype of acute leukaemias.
Bone marrow transplantation 1989;4 Suppl 1():66-9.
1988: G Cimino; Francesco Lo Coco; Claudio Cartoni; T Gallerano; M Luciani; M Lopez; Giulio De Rossi
Immune-deficiency in Hodgkin's disease (HD): a study of patients and healthy relatives in families with multiple cases.
European journal of cancer & clinical oncology 1988;24(10):1595-601.
1987: Giulio De Rossi; M A Aloe Spiriti; Arturo Cafolla; R Gastaldi; Francesco Lo Coco; M Lopez; M Luciani; D Pasqualetti; Anna Maria Testi; Franco Mandelli
CALLA-negative, TdT- and CD7-positive acute lymphoblastic leukemia: a phenotype associated with poor prognosis.
Diagnostic and clinical immunology 1987;5(3):140-3.
1986: Francesco Lo Coco; Arturo Cafolla; M Lopez; M Martelli; D Pasqualetti; Giulio De Rossi
Terminal deoxynucleotidil transferase (TdT) activity in human leukemia. Quantitative evaluation with enzymatic immunoassay (EIA).
Haematologica 1986;71(4):345-7.