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Eng Lo

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
39
Wang, Xiaoying
20
Moskowitz, Michael
19
Lee, Seong-Ryong
17
Arai, Ken
13
Asahi, Minoru
12
Rosen, Bruce
10
Van Leyen, Klaus
10
Singhal, Aneesh
10
Sumii, Toshihisa
9
Tejima, Emiri
9
Mori, Tatsuro
8
Pierce, AR
8
Tsuji, Kiyoshi
8
Steinberg, Gary
7
Dijkhuizen, Rick

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Publications

TOP 3
Pallast Stefanie; Arai Ken; Wang Xiaoying; Lo Eng H; van Leyen Klaus
12/15-Lipoxygenase targets neuronal mitochondria under oxidative stress.
Arai Ken; Lo Eng H
Oligovascular signaling in white matter stroke.
Arai Ken; Jin Guang; Navaratna Deepti; Lo Eng H
Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke.

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All Publications

2009: Pallast Stefanie; Arai Ken; Wang Xiaoying; Lo Eng H; van Leyen Klaus
12/15-Lipoxygenase targets neuronal mitochondria under oxidative stress.
Journal of neurochemistry 2009;111(3):882-9.
2009: Arai Ken; Lo Eng H
Oligovascular signaling in white matter stroke.
Biological & pharmaceutical bulletin 2009;32(10):1639-44.
2009: Arai Ken; Jin Guang; Navaratna Deepti; Lo Eng H
Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke.
The FEBS journal 2009;276(17):4644-52.
2009: Lo Eng H
T time in the brain.
Nature medicine 2009;15(8):844-6.
2009: Foerch C; Montaner J; Furie K L; Ning M M; Lo E H
Invited Article: Searching for oracles? Blood biomarkers in acute stroke.
Neurology 2009;73(5):393-9.
2009: Park Kyung-Pil; Rosell Anna; Foerch Christian; Xing Changhong; Kim Woo Jean; Lee Seoul; Opdenakker Ghislain; Furie Karen L; Lo Eng H
Plasma and brain matrix metalloproteinase-9 after acute focal cerebral ischemia in rats.
Stroke; a journal of cerebral circulation 2009;40(8):2836-42.
2009: Yu Z; Liu J; Guo S; Xing C; Fan X; Ning M; Yuan J C; Lo E H; Wang X
Neuroglobin-overexpression alters hypoxic response gene expression in primary neuron culture following oxygen glucose deprivation.
Neuroscience 2009;162(2):396-403.
2009: Xing Changhong; Lee Sunryung; Kim Woo Jean; Wang Hui; Yang Yong-Guang; Ning MingMing; Wang Xiaoying; Lo Eng H
Neurovascular effects of CD47 signaling: promotion of cell death, inflammation, and suppression of angiogenesis in brain endothelial cells in vitro.
Journal of neuroscience research 2009;87(11):2571-7.
2009: Ji Ru-Rong; Xu Zhen-Zhong; Wang Xiaoying; Lo Eng H
Matrix metalloprotease regulation of neuropathic pain.
Trends in pharmacological sciences 2009;30(7):336-40.
2009: Fisher Marc; Feuerstein Giora; Howells David W; Hurn Patricia D; Kent Thomas A; Savitz Sean I; Lo Eng H;
Update of the stroke therapy academic industry roundtable preclinical recommendations.
Stroke; a journal of cerebral circulation 2009;40(6):2244-50.
2009: Foerch Christian; Arai Ken; Van Cott Elizabeth Merrill; van Leyen Klaus; Lo Eng H
Rapid reversal of anticoagulation reduces hemorrhage volume in a mouse model of warfarin-associated intracerebral hemorrhage.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(5):1015-21.
2009: Rosell Anna; Arai Ken; Lok Josephine; He Tongrong; Guo Shuzhen; Navarro Miriam; Montaner Joan; Katusic Zvonimir S; Lo Eng H
Interleukin-1beta augments angiogenic responses of murine endothelial progenitor cells in vitro.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(5):933-43.
2009: Jin Guang; Tsuji Kiyoshi; Xing Changhong; Yang Yong-Guang; Wang Xiaoying; Lo Eng H
CD47 gene knockout protects against transient focal cerebral ischemia in mice.
Experimental neurology 2009;217(1):165-70.
2009: Lee Hyung; Park Jong-Wook; Kim Sang-Pyo; Lo Eng H; Lee Seong-Ryong
Doxycycline inhibits matrix metalloproteinase-9 and laminin degradation after transient global cerebral ischemia.
Neurobiology of disease 2009;34(2):189-98.
2009: Lu Jie; Dai Guangping; Egi Yasu; Huang Shuning; Kwon Seon Joo; Lo Eng H; Kim Young Ro
Characterization of cerebrovascular responses to hyperoxia and hypercapnia using MRI in rat.
NeuroImage 2009;45(4):1126-34.
2009: Navaratna Deepti; Guo Shuzhen; Arai Ken; Lo Eng H
Mechanisms and targets for angiogenic therapy after stroke.
Cell adhesion & migration 2009;3(2):216-23.
2009: Arai Ken; Lo Eng H
An oligovascular niche: cerebral endothelial cells promote the survival and proliferation of oligodendrocyte precursor cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(14):4351-5.
2009: Yu Zhanyang; Fan Xiang; Lo Eng H; Wang Xiaoying
Neuroprotective roles and mechanisms of neuroglobin.
Neurological research 2009;31(2):122-7.
2009: Guo Shuzhen; Lo Eng H
Dysfunctional cell-cell signaling in the neurovascular unit as a paradigm for central nervous system disease.
Stroke; a journal of cerebral circulation 2009;40(3 Suppl):S4-7.
2009: Lo Eng H; Rosenberg Gary A
The neurovascular unit in health and disease: introduction.
Stroke; a journal of cerebral circulation 2009;40(3 Suppl):S2-3.
2009: Guo Shuzhen; Arai Ken; Stins Monique F; Chuang De-Maw; Lo Eng H
Lithium upregulates vascular endothelial growth factor in brain endothelial cells and astrocytes.
Stroke; a journal of cerebral circulation 2009;40(2):652-5.
2009: Park Jong-Wan; Jang Young-Ho; Kim Jin-Mo; Lee Hyung; Park Weon-Kyun; Lim Man-Bin; Chu Yeun-Kyung; Lo Eng H; Lee Seong-Ryong
Green tea polyphenol (-)-epigallocatechin gallate reduces neuronal cell damage and up-regulation of MMP-9 activity in hippocampal CA1 and CA2 areas following transient global cerebral ischemia.
Journal of neuroscience research 2009;87(2):567-75.
2009: Lok Josephine; Sardi S Pablo; Guo Shuzhen; Besancon Elaine; Ha Duy M; Rosell Anna; Kim Woo Jean; Corfas Gabriel; Lo Eng H
Neuregulin-1 signaling in brain endothelial cells.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(1):39-43.
2009: Fujiwara Norio; Murata Yoshihiro; Arai Ken; Egi Yasuhiro; Lu Jie; Wu Ona; Singhal Aneesh B; Lo Eng H
Combination therapy with normobaric oxygen (NBO) plus thrombolysis in experimental ischemic stroke.
BMC neuroscience 2009;10():79.
2008: Devor Anna; Hillman Elizabeth M C; Tian Peifang; Waeber Christian; Teng Ivan C; Ruvinskaya Lana; Shalinsky Mark H; Zhu Haihao; Haslinger Robert H; Narayanan Suresh N; Ulbert Istvan; Dunn Andrew K; Lo Eng H; Rosen Bruce R; Dale Anders M; Kleinfeld David; Boas David A
Stimulus-induced changes in blood flow and 2-deoxyglucose uptake dissociate in ipsilateral somatosensory cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(53):14347-57.
2008: Murata Yoshihiro; Rosell Anna; Scannevin Robert H; Rhodes Kenneth J; Wang Xiaoying; Lo Eng H
Extension of the thrombolytic time window with minocycline in experimental stroke.
Stroke; a journal of cerebral circulation 2008;39(12):3372-7.
2008: Foerch Christian; Arai Ken; Jin Guang; Park Kyung-Pil; Pallast Stefanie; van Leyen Klaus; Lo Eng H
Experimental model of warfarin-associated intracerebral hemorrhage.
Stroke; a journal of cerebral circulation 2008;39(12):3397-404.
2008: Kim Y R; Tejima E; Huang S; Atochin D N; Dai G; Lo E H; Huang P L; Bogdanov A; Rosen B R
In vivo quantification of transvascular water exchange during the acute phase of permanent stroke.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2008;60(4):813-21.
2008: Jin Guang; Arai Ken; Murata Yoshihiro; Wang Sophia; Stins Monique F; Lo Eng H; van Leyen Klaus
Protecting against cerebrovascular injury: contributions of 12/15-lipoxygenase to edema formation after transient focal ischemia.
Stroke; a journal of cerebral circulation 2008;39(9):2538-43.
2008: Wang Xiaoying; Rosell Anna; Lo Eng H
Targeting extracellular matrix proteolysis for hemorrhagic complications of tPA stroke therapy.
CNS & neurological disorders drug targets 2008;7(3):235-42.
2008: Wang Xiaoying; Liu Jianxiang; Zhu Haihao; Tejima Emiri; Tsuji Kiyoshi; Murata Yoshihiro; Atochin Dmitriy N; Huang Paul L; Zhang Chenggang; Lo Eng H
Effects of neuroglobin overexpression on acute brain injury and long-term outcomes after focal cerebral ischemia.
Stroke; a journal of cerebral circulation 2008;39(6):1869-74.
2008: Guo Shuzhen; Kim Woo Jean; Lok Josephine; Lee Sun-Ryung; Besancon Elaine; Luo Bing-Hao; Stins Monique F; Wang Xiaoying; Dedhar Shoukat; Lo Eng H
Neuroprotection via matrix-trophic coupling between cerebral endothelial cells and neurons.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(21):7582-7.
2008: Lo Eng H
A new penumbra: transitioning from injury into repair after stroke.
Nature medicine 2008;14(5):497-500.
2008: Sun Phillip Zhe; Murata Yoshihiro; Lu Jie; Wang Xiaoying; Lo Eng H; Sorensen A Gregory
Relaxation-compensated fast multislice amide proton transfer (APT) imaging of acute ischemic stroke.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2008;59(5):1175-82.
2008: Besancon Elaine; Guo Shuzhen; Lok Josephine; Tymianski Michael; Lo Eng H
Beyond NMDA and AMPA glutamate receptors: emerging mechanisms for ionic imbalance and cell death in stroke.
Trends in pharmacological sciences 2008;29(5):268-75.
2008: Rosell Anna; Cuadrado Eloy; Ortega-Aznar Arantxa; Hernández-Guillamon Mar; Lo Eng H; Montaner Joan
MMP-9-positive neutrophil infiltration is associated to blood-brain barrier breakdown and basal lamina type IV collagen degradation during hemorrhagic transformation after human ischemic stroke.
Stroke; a journal of cerebral circulation 2008;39(4):1121-6.
2008: Kawasaki Yasuhiko; Xu Zhen-Zhong; Wang Xiaoying; Park Jong Yeon; Zhuang Zhi-Ye; Tan Ping-Heng; Gao Yong-Jing; Roy Kristine; Corfas Gabriel; Lo Eng H; Ji Ru-Rong
Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain.
Nature medicine 2008;14(3):331-6.
2008: Lo E H
Experimental models, neurovascular mechanisms and translational issues in stroke research.
British journal of pharmacology 2008;153 Suppl 1():S396-405.
2008: van Leyen Klaus; Arai Ken; Jin Guang; Kenyon Victor; Gerstner Bettina; Rosenberg Paul A; Holman Theodore R; Lo Eng H
Novel lipoxygenase inhibitors as neuroprotective reagents.
Journal of neuroscience research 2008;86(4):904-9.
2008: Whalen Michael J; Dalkara Turgay; You Zerong; Qiu Jianhua; Bermpohl Daniela; Mehta Niyati; Suter Bernhard; Bhide Pradeep G; Lo Eng H; Ericsson Maria; Moskowitz Michael A
Acute plasmalemma permeability and protracted clearance of injured cells after controlled cortical impact in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(3):490-505.
2008: Rosell Anna; Lo Eng H
Multiphasic roles for matrix metalloproteinases after stroke.
Current opinion in pharmacology 2008;8(1):82-9.
2008: Kim Young R; van Meer Maurits P A; Tejima Emiri; Murata Yoshi; Mandeville Joseph B; Dai George; Chuang De-Maw; Rosen Bruce R; Lo Eng H
Functional MRI of delayed chronic lithium treatment in rat focal cerebral ischemia.
Stroke; a journal of cerebral circulation 2008;39(2):439-47.
2008: Singhal Aneesh B; Lo Eng H
Advances in emerging nondrug therapies for acute stroke 2007.
Stroke; a journal of cerebral circulation 2008;39(2):289-91.
2008: Kelly Peter J; Morrow Jason D; Ning MingMing; Koroshetz Walter; Lo Eng H; Terry Erin; Milne Ginger L; Hubbard Jane; Lee Hang; Stevenson Elizabeth; Lederer Megan; Furie Karen L
Oxidative stress and matrix metalloproteinase-9 in acute ischemic stroke: the Biomarker Evaluation for Antioxidant Therapies in Stroke (BEAT-Stroke) study.
Stroke; a journal of cerebral circulation 2008;39(1):100-4.
2008: Rosell A; Foerch C; Murata Y; Lo E H
Mechanisms and markers for hemorrhagic transformation after stroke.
Acta neurochirurgica. Supplement 2008;105():173-8.
2008: Ning Mingming; Wang Xiaoying; Lo Eng H
Chapter 6 Reperfusion injury after stroke: neurovascular proteases and the blood-brain barrier.
Handbook of clinical neurology / edited by P.J. Vinken and G.W. Bruyn 2008;92():117-36.
2007: Lok Josephine; Wang Hui; Murata Yoshihiro; Zhu Hai Hao; Qin Tao; Whalen Michael J; Lo Eng H
Effect of neuregulin-1 on histopathological and functional outcome after controlled cortical impact in mice.
Journal of neurotrauma 2007;24(12):1817-22.
2007: Lok Josephine; Gupta Punkaj; Guo Shuzhen; Kim Woo Jean; Whalen Michael J; van Leyen Klaus; Lo Eng H
Cell-cell signaling in the neurovascular unit.
Neurochemical research 2007;32(12):2032-45.
2007: Lee S-R; Lok J; Rosell A; Kim H-Y; Murata Y; Atochin D; Huang P L; Wang X; Ayata C; Moskowitz M A; Lo E H
Reduction of hippocampal cell death and proteolytic responses in tissue plasminogen activator knockout mice after transient global cerebral ischemia.
Neuroscience 2007;150(1):50-7.
2007: Bermpohl Daniela; You Zerong; Lo Eng H; Kim Hyung-Hwan; Whalen Michael J
TNF alpha and Fas mediate tissue damage and functional outcome after traumatic brain injury in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(11):1806-18.
2007: Shin Hwa Kyoung; Dunn Andrew K; Jones Phillip B; Boas David A; Lo Eng H; Moskowitz Michael A; Ayata Cenk
Normobaric hyperoxia improves cerebral blood flow and oxygenation, and inhibits peri-infarct depolarizations in experimental focal ischaemia.
Brain : a journal of neurology 2007;130(Pt 6):1631-42.
2007: Lee Sun-Ryung; Guo Shu-Zhen; Scannevin Robert H; Magliaro Brian C; Rhodes Kenneth J; Wang Xiaoying; Lo Eng H
Induction of matrix metalloproteinase, cytokines and chemokines in rat cortical astrocytes exposed to plasminogen activators.
Neuroscience letters 2007;417(1):1-5.
2007: Tejima Emiri; Zhao Bing-Qiao; Tsuji Kiyoshi; Rosell Anna; van Leyen Klaus; Gonzalez R Gilberto; Montaner Joan; Wang Xiaoying; Lo Eng H
Astrocytic induction of matrix metalloproteinase-9 and edema in brain hemorrhage.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(3):460-8.
2007: Zhao Bing-Qiao; Tejima Emiri; Lo Eng H
Neurovascular proteases in brain injury, hemorrhage and remodeling after stroke.
Stroke; a journal of cerebral circulation 2007;38(2 Suppl):748-52.
2007: Kim Young R; van Meer Maurits P A; Mandeville Joseph B; Tejima Emiri; Dai George; Topalkara Kamil; Qui Jianhua; Dijkhuizen Rick M; Moskowitz Michael A; Lo Eng H; Rosen Bruce R
fMRI of delayed albumin treatment during stroke recovery in rats: implication for fast neuronal habituation in recovering brains.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(1):142-53.
2007: Wu Ona; Sumii Toshihisa; Asahi Minoru; Sasamata Masao; Ostergaard Leif; Rosen Bruce R; Lo Eng H; Dijkhuizen Rick M
Infarct prediction and treatment assessment with MRI-based algorithms in experimental stroke models.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(1):196-204.
2006: Kim Dong-Eog; Tsuji Kiyoshi; Kim Young Ro; Mueller Franz-Josef; Eom Hyeon-Seok; Snyder Evan Y; Lo Eng H; Weissleder Ralph; Schellingerhout Dawid
Neural stem cell transplant survival in brains of mice: assessing the effect of immunity and ischemia by using real-time bioluminescent imaging.
Radiology 2006;241(3):822-30.
2006: van Leyen Klaus; Kim Hahn Young; Lee Seong-Ryong; Jin Guang; Arai Ken; Lo Eng H
Baicalein and 12/15-lipoxygenase in the ischemic brain.
Stroke; a journal of cerebral circulation 2006;37(12):3014-8.
2006: Guo Shuzhen; Wang Sophia; Kim Woo Jean; Lee Sun-Ryung; Frosch Matthew P; Bacskai Brian J; Greenberg Steven M; Lo Eng H
Effects of apoE isoforms on beta-amyloid-induced matrix metalloproteinase-9 in rat astrocytes.
Brain research 2006;1111(1):222-6.
2006: Wang Sophia; Lee Sun-Ryung; Guo Shu-Zhen; Kim Woo Jean; Montaner Joan; Wang Xiaoying; Lo Eng H
Reduction of tissue plasminogen activator-induced matrix metalloproteinase-9 by simvastatin in astrocytes.
Stroke; a journal of cerebral circulation 2006;37(7):1910-2.
2006: Rosell Anna; Ortega-Aznar Arantxa; Alvarez-Sabín José; Fernández-Cadenas Israel; Ribó Marc; Molina Carlos A; Lo Eng H; Montaner Joan
Increased brain expression of matrix metalloproteinase-9 after ischemic and hemorrhagic human stroke.
Stroke; a journal of cerebral circulation 2006;37(6):1399-406.
2006: Ning M; Furie K L; Koroshetz W J; Lee H; Barron M; Lederer M; Wang X; Zhu M; Sorensen A G; Lo E H; Kelly P J
Association between tPA therapy and raised early matrix metalloproteinase-9 in acute stroke.
Neurology 2006;66(10):1550-5.
2006: Zhao Bing-Qiao; Wang Sophia; Kim Hahn-Young; Storrie Hannah; Rosen Bruce R; Mooney David J; Wang Xiaoying; Lo Eng H
Role of matrix metalloproteinases in delayed cortical responses after stroke.
Nature medicine 2006;12(4):441-5.
2006: Lee Seong-Ryong; Kim Hahn-Young; Rogowska Jadwiga; Zhao Bing-Qiao; Bhide Pradeep; Parent Jack M; Lo Eng H
Involvement of matrix metalloproteinase in neuroblast cell migration from the subventricular zone after stroke.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(13):3491-5.
2006: Flaumenhaft Robert; Lo Eng H
Different strokes for rodent folks.
Nature methods 2006;3(2):79-80.
2005: Lee Soon-Tae; Chu Kon; Jung Keun-Hwa; Ko Song-Yi; Kim Eun-Hee; Sinn Dong In; Lee Yong Seok; Lo Eng H; Kim Manho; Roh Jae Kyu
Granulocyte colony-stimulating factor enhances angiogenesis after focal cerebral ischemia.
Brain research 2005;1058(1-2):120-8.
2005: Pham Wellington; Zhao Bing-Qiao; Lo Eng H; Medarova Zdravka; Rosen Bruce; Moore Anna
Crossing the blood-brain barrier: a potential application of myristoylated polyarginine for in vivo neuroimaging.
NeuroImage 2005;28(1):287-92.
2005: Tsuji Kiyoshi; Aoki Toshiaki; Tejima Emiri; Arai Ken; Lee Sun-Ryung; Atochin Dmitriy N; Huang Paul L; Wang Xiaoying; Montaner Joan; Lo Eng H
Tissue plasminogen activator promotes matrix metalloproteinase-9 upregulation after focal cerebral ischemia.
Stroke; a journal of cerebral circulation 2005;36(9):1954-9.
2005: Singhal Aneesh B; Lo Eng H; Dalkara Turgay; Moskowitz Michael A
Advances in stroke neuroprotection: hyperoxia and beyond.
Neuroimaging clinics of North America 2005;15(3):697-720, xii-xiii.
2005: Kim Young R; Huang In J; Lee Seong-Ryong; Tejima Emiri; Mandeville Joseph B; van Meer Maurits P A; Dai George; Choi Yong W; Dijkhuizen Rick M; Lo Eng H; Rosen Bruce R
Measurements of BOLD/CBV ratio show altered fMRI hemodynamics during stroke recovery in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(7):820-9.
2005: Asahi Minoru; Huang Zhihong; Thomas Sunu; Yoshimura Shin-ichi; Sumii Toshihisa; Mori Tatsuro; Qiu Jianhua; Amin-Hanjani Sepideh; Huang Paul L; Liao James K; Lo Eng H; Moskowitz Michael A
Protective effects of statins involving both eNOS and tPA in focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(6):722-9.
2005: Kim Hahn Young; Singhal Aneesh B; Lo Eng H
Normobaric hyperoxia extends the reperfusion window in focal cerebral ischemia.
Annals of neurology 2005;57(4):571-5.
2005: Singhal Aneesh B; Benner Thomas; Roccatagliata Luca; Koroshetz Walter J; Schaefer Pamela W; Lo Eng H; Buonanno Ferdinando S; Gonzalez R Gilberto; Sorensen A Gregory
A pilot study of normobaric oxygen therapy in acute ischemic stroke.
Stroke; a journal of cerebral circulation 2005;36(4):797-802.
2005: van Leyen Klaus; Siddiq Ambreena; Ratan Rajiv R; Lo Eng H
Proteasome inhibition protects HT22 neuronal cells from oxidative glutamate toxicity.
Journal of neurochemistry 2005;92(4):824-30.
2005: Lo Eng H; Moskowitz Michael A; Jacobs Thomas P
Exciting, radical, suicidal: how brain cells die after stroke.
Stroke; a journal of cerebral circulation 2005;36(2):189-92.
2004: Lee Sun-Ryung; Wang Xiaoying; Tsuji Kiyoshi; Lo Eng H
Extracellular proteolytic pathophysiology in the neurovascular unit after stroke.
Neurological research 2004;26(8):854-61.
2004: Lo Eng H
Combination stroke therapy: easy as APC?
Nature medicine 2004;10(12):1295-6.
2004: Wang Xiaoying; Tsuji Kiyoshi; Lee Sun-Ryung; Ning MingMing; Furie Karen L; Buchan Alastair M; Lo Eng H
Mechanisms of hemorrhagic transformation after tissue plasminogen activator reperfusion therapy for ischemic stroke.
Stroke; a journal of cerebral circulation 2004;35(11 Suppl 1):2726-30.
2004: Kaur Jaspreet; Zhao Zonghang; Klein Gary M; Lo Eng H; Buchan Alastair M
The neurotoxicity of tissue plasminogen activator?
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2004;24(9):945-63.
2004: Lee Sun-Ryung; Lo Eng H
Induction of caspase-mediated cell death by matrix metalloproteinases in cerebral endothelial cells after hypoxia-reoxygenation.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2004;24(7):720-7.
2004: Gursoy-Ozdemir Yasemin; Qiu Jianhua; Matsuoka Norihiro; Bolay Hayrunnisa; Bermpohl Daniela; Jin Hongwei; Wang Xiaoying; Rosenberg Gary A; Lo Eng H; Moskowitz Michael A
Cortical spreading depression activates and upregulates MMP-9.
The Journal of clinical investigation 2004;113(10):1447-55.
2004: Arai Ken; Lee Sun-Ryung; van Leyen Klaus; Kurose Hitoshi; Lo Eng H
Involvement of ERK MAP kinase in endoplasmic reticulum stress in SH-SY5Y human neuroblastoma cells.
Journal of neurochemistry 2004;89(1):232-9.
2004: Tian Xuejun; Gotoh Takaya; Tsuji Kiyoshi; Lo Eng H; Huang Su; Feig Larry A
Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB.
The EMBO journal 2004;23(7):1567-75.
2004: Lo Eng H; Broderick Joseph P; Moskowitz Michael A
tPA and proteolysis in the neurovascular unit.
Stroke; a journal of cerebral circulation 2004;35(2):354-6.
2004: Lee Seong-Ryong; Tsuji Kiyoshi; Lee Sun-Ryung; Lo Eng H
Role of matrix metalloproteinases in delayed neuronal damage after transient global cerebral ischemia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(3):671-8.
2003: Wang Xiaoying; Lo Eng H
Triggers and mediators of hemorrhagic transformation in cerebral ischemia.
Molecular neurobiology 2003;28(3):229-44.
2003: Lee Sun-Ryung; Lo Eng H
Interactions between p38 mitogen-activated protein kinase and caspase-3 in cerebral endothelial cell death after hypoxia-reoxygenation.
Stroke; a journal of cerebral circulation 2003;34(11):2704-9.
2003: Wang Xiaoying; Lee Sun-Ryung; Arai Ken; Lee Seong-Ryong; Tsuji Kiyoshi; Rebeck G William; Lo Eng H
Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator.
Nature medicine 2003;9(10):1313-7.
2003: Arai Ken; Lee Sun-Ryung; Lo Eng H
Essential role for ERK mitogen-activated protein kinase in matrix metalloproteinase-9 regulation in rat cortical astrocytes.
Glia 2003;43(3):254-64.
2003: Asahi Minoru; Rammohan Ram; Sumii Toshihisa; Wang Xiaoying; Pauw Robert Jan; Weissig Volkmar; Torchilin Vladimir P; Lo Eng H
Antiactin-targeted immunoliposomes ameliorate tissue plasminogen activator-induced hemorrhage after focal embolic stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(8):895-9.
2003: Lo Eng H; Dalkara Turgay; Moskowitz Michael A
Mechanisms, challenges and opportunities in stroke.
Nature reviews. Neuroscience 2003;4(5):399-415.
2003: Moskowitz Michael A; Lo Eng H
Neurogenesis and apoptotic cell death.
Stroke; a journal of cerebral circulation 2003;34(2):324-6.
2003: Dijkhuizen Rick M; Singhal Aneesh B; Mandeville Joseph B; Wu Ona; Halpern Elkan F; Finklestein Seth P; Rosen Bruce R; Lo Eng H
Correlation between brain reorganization, ischemic damage, and neurologic status after transient focal cerebral ischemia in rats: a functional magnetic resonance imaging study.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(2):510-7.
2002: Petty Margaret A; Lo Eng H
Junctional complexes of the blood-brain barrier: permeability changes in neuroinflammation.
Progress in neurobiology 2002;68(5):311-23.
2002: Mori Tatsuro; Wang Xiaoying; Aoki Toshiaki; Lo Eng H
Downregulation of matrix metalloproteinase-9 and attenuation of edema via inhibition of ERK mitogen activated protein kinase in traumatic brain injury.
Journal of neurotrauma 2002;19(11):1411-9.
2002: Aoki Toshiaki; Sumii Toshihisa; Mori Tatsuro; Wang Xiaoying; Lo Eng H
Blood-brain barrier disruption and matrix metalloproteinase-9 expression during reperfusion injury: mechanical versus embolic focal ischemia in spontaneously hypertensive rats.
Stroke; a journal of cerebral circulation 2002;33(11):2711-7.
2002: Ge Yinlin; Wang Xiaoying; Chen Zhihong; Landman Natalie; Lo Eng H; Kang Jing X
Gene transfer of the Caenorhabditis elegans n-3 fatty acid desaturase inhibits neuronal apoptosis.
Journal of neurochemistry 2002;82(6):1360-6.
2002: Dijkhuizen Rick M; Asahi Minoru; Wu Ona; Rosen Bruce R; Lo Eng H
Rapid breakdown of microvascular barriers and subsequent hemorrhagic transformation after delayed recombinant tissue plasminogen activator treatment in a rat embolic stroke model.
Stroke; a journal of cerebral circulation 2002;33(8):2100-4.
2002: Singhal Aneesh B; Wang Xiaoying; Sumii Toshihisa; Mori Tatsuro; Lo Eng H
Effects of normobaric hyperoxia in a rat model of focal cerebral ischemia-reperfusion.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(7):861-8.
2002: Lo Eng H; Wang Xiaoying; Cuzner M Louise
Extracellular proteolysis in brain injury and inflammation: role for plasminogen activators and matrix metalloproteinases.
Journal of neuroscience research 2002;69(1):1-9.
2002: Wang Xiaoying; Mori Tatsuro; Sumii Toshihisa; Lo Eng H
Hemoglobin-induced cytotoxicity in rat cerebral cortical neurons: caspase activation and oxidative stress.
Stroke; a journal of cerebral circulation 2002;33(7):1882-8.
2002: Wang Xiaoying; Mori Tatsuro; Jung Jae-Chang; Fini M Elizabeth; Lo Eng H
Secretion of matrix metalloproteinase-2 and -9 after mechanical trauma injury in rat cortical cultures and involvement of MAP kinase.
Journal of neurotrauma 2002;19(5):615-25.
2002: Mori Tatsuro; Wang Xiaoying; Jung Jae-Chang; Sumii Toshihisa; Singhal Aneesh B; Fini M Elizabeth; Dixon C Edward; Alessandrini Alessandro; Lo Eng H
Mitogen-activated protein kinase inhibition in traumatic brain injury: in vitro and in vivo effects.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(4):444-52.
2002: Singhal Aneesh B; Dijkhuizen Rick M; Rosen Bruce R; Lo Eng H
Normobaric hyperoxia reduces MRI diffusion abnormalities and infarct size in experimental stroke.
Neurology 2002;58(6):945-52.
2002: Sumii Toshihisa; Lo Eng H
Involvement of matrix metalloproteinase in thrombolysis-associated hemorrhagic transformation after embolic focal ischemia in rats.
Stroke; a journal of cerebral circulation 2002;33(3):831-6.
2001: Mori T; Wang X; Kline A E; Siao C J; Dixon C E; Tsirka S E; Lo E H
Reduced cortical injury and edema in tissue plasminogen activator knockout mice after brain trauma.
Neuroreport 2001;12(18):4117-20.
2001: Wang X; Shimizu-Sasamata M; Moskowitz M A; Newcomb R; Lo E H
Profiles of glutamate and GABA efflux in core versus peripheral zones of focal cerebral ischemia in mice.
Neuroscience letters 2001;313(3):121-4.
2001: Asahi M; Wang X; Mori T; Sumii T; Jung J C; Moskowitz M A; Fini M E; Lo E H
Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(19):7724-32.
2001: Asahi M; Sumii T; Fini M E; Itohara S; Lo E H
Matrix metalloproteinase 2 gene knockout has no effect on acute brain injury after focal ischemia.
Neuroreport 2001;12(13):3003-7.
2001: Dijkhuizen R M; Asahi M; Wu O; Rosen B R; Lo E H
Delayed rt-PA treatment in a rat embolic stroke model: diagnosis and prognosis of ischemic injury and hemorrhagic transformation with magnetic resonance imaging.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2001;21(8):964-71.
2001: Tejima E; Katayama Y; Suzuki Y; Kano T; Lo E H
Hemorrhagic transformation after fibrinolysis with tissue plasminogen activator: evaluation of role of hypertension with rat thromboembolic stroke model.
Stroke; a journal of cerebral circulation 2001;32(6):1336-40.
2001: Sumii T; Singhal A B; Asahi M; Shimizu-Sasamata M; Suzuki M; Miyata K; Lo E H
Protective effects of pamiteplase, a modified t-PA, in a rat model of embolic stroke.
Neuroreport 2001;12(3):615-8.
2000: Asahi M; Asahi K; Jung J C; del Zoppo G J; Fini M E; Lo E H
Role for matrix metalloproteinase 9 after focal cerebral ischemia: effects of gene knockout and enzyme inhibition with BB-94.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(12):1681-9.
2000: Wang X; Jung J; Asahi M; Chwang W; Russo L; Moskowitz M A; Dixon C E; Fini M E; Lo E H
Effects of matrix metalloproteinase-9 gene knock-out on morphological and motor outcomes after traumatic brain injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(18):7037-42.
2000: Asahi M; Asahi K; Wang X; Lo E H
Reduction of tissue plasminogen activator-induced hemorrhage and brain injury by free radical spin trapping after embolic focal cerebral ischemia in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(3):452-7.
2000: Matsushita K; Meng W; Wang X; Asahi M; Asahi K; Moskowitz M A; Lo E H
Evidence for apoptosis after intercerebral hemorrhage in rat striatum.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(2):396-404.
2000: Kano T; Katayama Y; Tejima E; Lo E H
Hemorrhagic transformation after fibrinolytic therapy with tissue plasminogen activator in a rat thromboembolic model of stroke.
Brain research 2000;854(1-2):245-8.
2000: Ayata C; Shimizu-Sasamata M; Lo E H; Noebels J L; Moskowitz M A
Impaired neurotransmitter release and elevated threshold for cortical spreading depression in mice with mutations in the alpha1A subunit of P/Q type calcium channels.
Neuroscience 2000;95(3):639-45.
1999: Meng W; Wang X; Asahi M; Kano T; Asahi K; Ackerman R H; Lo E H
Effects of tissue type plasminogen activator in embolic versus mechanical models of focal cerebral ischemia in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1999;19(12):1316-21.
1999: Wang X; Asahi M; Lo E H
Tissue type plasminogen activator amplifies hemoglobin-induced neurotoxicity in rat neuronal cultures.
Neuroscience letters 1999;274(2):79-82.
1998: Newcomb R; Pierce A R; Kano T; Meng W; Bosque-Hamilton P; Taylor L; Curthoys N; Lo E H
Characterization of mitochondrial glutaminase and amino acids at prolonged times after experimental focal cerebral ischemia.
Brain research 1998;813(1):103-11.
1998: Shimizu-Sasamata M; Bosque-Hamilton P; Huang P L; Moskowitz M A; Lo E H
Attenuated neurotransmitter release and spreading depression-like depolarizations after focal ischemia in mutant mice with disrupted type I nitric oxide synthase gene.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(22):9564-71.
1998: Shimizu-Sasamata M; Kano T; Rogowska J; Wolf G L; Moskowitz M A; Lo E H
YM872, a highly water-soluble AMPA receptor antagonist, preserves the hemodynamic penumbra and reduces brain injury after permanent focal ischemia in rats.
Stroke; a journal of cerebral circulation 1998;29(10):2141-8.
1998: Kano T; Shimizu-Sasamata M; Huang P L; Moskowitz M A; Lo E H
Effects of nitric oxide synthase gene knockout on neurotransmitter release in vivo.
Neuroscience 1998;86(3):695-9.
1998: Lo E H; Bosque-Hamilton P; Meng W
Inhibition of poly(ADP-ribose) polymerase: reduction of ischemic injury and attenuation of N-methyl-D-aspartate-induced neurotransmitter dysregulation.
Stroke; a journal of cerebral circulation 1998;29(4):830-6.
1998: Lo E H; Pierce A R; Matsumoto K; Kano T; Evans C J; Newcomb R
Alterations in K+ evoked profiles of neurotransmitter and neuromodulator amino acids after focal ischemia-reperfusion.
Neuroscience 1998;83(2):449-58.
1997: Lo E H; Pierce A R; Mandeville J B; Rosen B R
Neuroprotection with NBQX in rat focal cerebral ischemia. Effects on ADC probability distribution functions and diffusion-perfusion relationships.
Stroke; a journal of cerebral circulation 1997;28(2):439-46; discussion 446-7.
1997: Pierce A R; Lo E H; Mandeville J B; Gonzalez R G; Rosen B R; Wolf G L
MRI measurements of water diffusion and cerebral perfusion: their relationship in a rat model of focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(2):183-90.
1996: Hamberg L M; Hunter G J; Kierstead D; Lo E H; Gilberto González R; Wolf G L
Measurement of cerebral blood volume with subtraction three-dimensional functional CT.
AJNR. American journal of neuroradiology 1996;17(10):1861-9.
1996: Lo E H; Hara H; Rogowska J; Trocha M; Pierce A R; Huang P L; Fishman M C; Wolf G L; Moskowitz M A
Temporal correlation mapping analysis of the hemodynamic penumbra in mutant mice deficient in endothelial nitric oxide synthase gene expression.
Stroke; a journal of cerebral circulation 1996;27(8):1381-5.
1996: Lo E H; Rogowska J; Batchelder K F; Wolf G L
Hemodynamic alterations in focal cerebral ischemia: temporal correlation analysis for functional imaging.
Neurological research 1996;18(2):150-6.
1996: Lo E H; Rogowska J; Bogorodzki P; Trocha M; Matsumoto K; Saffran B; Wolf G L
Temporal correlation analysis of penumbral dynamics in focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(1):60-8.
1996: Matsumoto K; Lo E H; Pierce A R; Halpern E F; Newcomb R
Secondary elevation of extracellular neurotransmitter amino acids in the reperfusion phase following focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(1):114-24.
1995: Pan Y; Lo E H; Matsumoto K; Hamberg L; Jiang H
Quantitative and dynamic MRI of neuroprotection in experimental stroke.
Journal of the neurological sciences 1995;131(2):128-34.
1995: Hunter J V; Batchelder K F; Lo E H; Wolf G L
Imaging techniques for in vivo quantitation of extracranial lymphatic drainage of the brain.
Neuropathology and applied neurobiology 1995;21(3):185-8.
1995: Matsumoto K; Lo E H; Pierce A R; Wei H; Garrido L; Kowall N W
Role of vasogenic edema and tissue cavitation in ischemic evolution on diffusion-weighted imaging: comparison with multiparameter MR and immunohistochemistry.
AJNR. American journal of neuroradiology 1995;16(5):1107-15.
1994: Lo E H; Matsumoto K; Pierce A R; Garrido L; Luttinger D
Pharmacologic reversal of acute changes in diffusion-weighted magnetic resonance imaging in focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1994;14(4):597-603.
1994: Lo E H; Pan Y; Matsumoto K; Kowall N W
Blood-brain barrier disruption in experimental focal ischemia: comparison between in vivo MRI and immunocytochemistry.
Magnetic resonance imaging 1994;12(3):403-11.
1993: Lo E H
A theoretical analysis of hemodynamic and biomechanical alterations in intracranial AVMs after radiosurgery.
International journal of radiation oncology, biology, physics 1993;27(2):353-61.
1993: Lo E H; Steinberg G K; Panahian N; Maidment N T; Newcomb R
Profiles of extracellular amino acid changes in focal cerebral ischaemia: effects of mild hypothermia.
Neurological research 1993;15(4):281-7.
1993: Lo E H
A haemodynamic analysis of intracranial arteriovenous malformations.
Neurological research 1993;15(1):51-5.
1992: Lo E H; Steinberg G K
Effects of hypothermia on evoked potentials, magnetic resonance imaging, and blood flow in focal ischemia in rabbits.
Stroke; a journal of cerebral circulation 1992;23(6):889-93.
1992: Lo E H; Frankel K A; Steinberg G K; DeLaPaz R L; Fabrikant J I
High-dose single-fraction brain irradiation: MRI, cerebral blood flow, electrophysiological, and histological studies.
International journal of radiation oncology, biology, physics 1992;22(1):47-55.
1991: Steinberg G K; Lo E H; Kunis D M; Grant G A; Poljak A; DeLaPaz R
Dextromethorphan alters cerebral blood flow and protects against cerebral injury following focal ischemia.
Neuroscience letters 1991;133(2):225-8.
1991: Lo E H; Steinberg G K
Effects of dextromethorphan on regional cerebral blood flow in focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1991;11(5):803-9.
1991: Lo E H; Sun G H; Steinberg G K
Effects of NMDA and calcium channel antagonists on regional cerebral blood flow.
Neuroscience letters 1991;131(1):17-20.
1991: Lo E H; DeLaPaz R L; Frankel K A; Poljak A; Phillips M H; Brennan K M; Woodruf K H; Valk P E; Steinberg G K; Fabrikant J I
MRI and PET of delayed heavy-ion radiation injury in the rabbit brain.
International journal of radiation oncology, biology, physics 1991;20(4):689-96.
1991: Lo E H; Fabrikant J I; Levy R P; Phillips M H; Frankel K A; Alpen E L
An experimental compartmental flow model for assessing the hemodynamic response of intracranial arteriovenous malformations to stereotactic radiosurgery.
Neurosurgery 1991;28(2):251-9.
1991: Lo E H; Fabrikant J I
Delayed biologic reactions to stereotactic charged-particle radiosurgery in the human brain.
Stereotactic and functional neurosurgery 1991;56(4):197-212.
1989: Lo E H; Frankel K A; Delapaz R L; Poljak A; Woodruff K H; Brennan K M; Phillips M H; Valk P E; Steinberg G K; Fabrikant J I
Cerebrovascular and metabolic perturbations in delayed heavy charged particle radiation injury.
Brain research 1989;504(1):168-72.

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