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Dennis Lo

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K C Allen Chan; Paul K S Chan; Yin Wah Chan; Anita S M Cheng; Emily C W Hung; Ann D King; Jeffrey S S Kwok; Franco P T Lai; Sing-Fai Leung; Teresa K C Tsui; Andrew C van Hasselt; John K S Woo; Sze Wan Yeung; Anthony T C Chan; Y M Dennis Lo
Early detection of nasopharyngeal carcinoma by plasma Epstein-Barr virus DNA analysis in a surveillance program.
Y M Dennis Lo
Noninvasive fetal whole-genome sequencing from maternal plasma: feasibility studies and future directions.
James Z Z Qu; Hao Sun; K C Allen Chan; Yvonne K Y Cheng; Rossa W K Chiu; Peiyong Jiang; Tak Y Leung; Gary J W Liao; Y M Dennis Lo
Noninvasive prenatal determination of twin zygosity by maternal plasma DNA analysis.

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2013: K C Allen Chan; Paul K S Chan; Yin Wah Chan; Anita S M Cheng; Emily C W Hung; Ann D King; Jeffrey S S Kwok; Franco P T Lai; Sing-Fai Leung; Teresa K C Tsui; Andrew C van Hasselt; John K S Woo; Sze Wan Yeung; Anthony T C Chan; Y M Dennis Lo
Early detection of nasopharyngeal carcinoma by plasma Epstein-Barr virus DNA analysis in a surveillance program.
Cancer 2013;119(10):1838-44.
2013: Y M Dennis Lo
Noninvasive fetal whole-genome sequencing from maternal plasma: feasibility studies and future directions.
Clinical chemistry 2013;59(4):601-3.
2013: James Z Z Qu; Hao Sun; K C Allen Chan; Yvonne K Y Cheng; Rossa W K Chiu; Peiyong Jiang; Tak Y Leung; Gary J W Liao; Y M Dennis Lo
Noninvasive prenatal determination of twin zygosity by maternal plasma DNA analysis.
Clinical chemistry 2013;59(2):427-35.
2012: Kwan-Wood G Lam; Tak Y Leung; Gary J W Liao; K C Allen Chan; Rossa W K Chiu; Peiyong Jiang; Y M Dennis Lo
Noninvasive prenatal diagnosis of monogenic diseases by targeted massively parallel sequencing of maternal plasma: application to β-thalassemia.
Clinical chemistry 2012;58(10):1467-75.
2012: Terence C W Poon; Joseph J Y Sung; Yu-Kwan Tong; Sai M Ngai; Ronald T K Pang; K C Allen Chan; Stephen S C Chim; Rossa W K Chiu; Nelson L S Lee; Y M Dennis Lo
Proteomic analysis reveals platelet factor 4 and beta-thromboglobulin as prognostic markers in severe acute respiratory syndrome.
Electrophoresis 2012;33(12):1894-900.
2012: Rossa W K Chiu; Y M Dennis Lo
Noninvasive prenatal diagnosis empowered by high-throughput sequencing.
Prenatal diagnosis 2012;32(4):401-6.
2012: Nader Rifai; Peter Wilding; Eleftherios P Diamandis; Larry J Kricka; Jack H Ladenson; Y M Dennis Lo; Carl T Wittwer
Advancing laboratory medicine through innovation: a tale of six inventors.
Clinical chemistry 2012;58(3):502-10.
2012: Yama W L Zheng; Fiona M F Lun; Xiaoxi Su; Hao Sun; John Wong; K C Allen Chan; Eric Z Chen; Rossa W K Chiu; Emily C W Hung; Peiyong Jiang; Paul B S Lai; Vincent Lee; Chi-Kong Li; Y M Dennis Lo
Nonhematopoietically derived DNA is shorter than hematopoietically derived DNA in plasma: a transplantation model.
Clinical chemistry 2012;58(3):549-58.
2012: Gary J W Liao; Rossa W K Chiu; Y M Dennis Lo
Prenatal assessment of fetal chromosomal and genetic disorders through maternal plasma DNA analysis.
Pathology 2012;44(2):69-72.
2012: Nancy B Y Tsui; Xiaoxi Su; Hao Sun; K C Allen Chan; Rossa W K Chiu; Katherine C K Chow; Peiyong Jiang; Tak Y Leung; Y M Dennis Lo
High resolution size analysis of fetal DNA in the urine of pregnant women by paired-end massively parallel sequencing.
PloS one 2012;7(10):e48319.
2012: Gary J W Liao; Hao Sun; K C Allen Chan; Rossa W K Chiu; Peiyong Jiang; Tak Y Leung; Y M Dennis Lo
Noninvasive prenatal diagnosis of fetal trisomy 21 by allelic ratio analysis using targeted massively parallel sequencing of maternal plasma DNA.
PloS one 2012;7(5):e38154.
2011: Y M Dennis Lo
Transplantation monitoring by plasma DNA sequencing.
Clinical chemistry 2011;57(7):941-2.
2011: Fiona M F Lun; Yoyo Y Jin; Hao Sun; Tak Y Leung; Tze K Lau; Rossa W K Chiu; Y M Dennis Lo
Noninvasive prenatal diagnosis of a case of Down syndrome due to robertsonian translocation by massively parallel sequencing of maternal plasma DNA.
Clinical chemistry 2011;57(6):917-9.
2011: Rossa W K Chiu; Y M Dennis Lo
Non-invasive prenatal diagnosis by fetal nucleic acid analysis in maternal plasma: the coming of age.
Seminars in fetal & neonatal medicine 2011;16(2):88-93.
2011: Nancy B Y Tsui; Rezan A Kadir; K C Allen Chan; Claudia Chi; Gillian Mellars; Edward G Tuddenham; Tak Y Leung; Tze K Lau; Rossa W K Chiu; Y M Dennis Lo
Noninvasive prenatal diagnosis of hemophilia by microfluidics digital PCR analysis of maternal plasma DNA.
Blood 2011;117(13):3684-91.
2011: Y M Dennis Lo
The quest for accurate measurement of fetal DNA in maternal plasma.
Clinical chemistry 2011;57(3):522-3.
2011: Daan van Abel; Marie van Dijk; Yama W L Zheng; Hao Sun; Eric Z Chen; Rossa W K Chiu; Dennis R Hölzel; Shushant Jain; Y M Dennis Lo; Fiona M F Lun; Cees B M Oudejans
SFRS7-mediated splicing of tau exon 10 is directly regulated by STOX1A in glial cells.
PloS one 2011;6(7):e21994.
2011: Eric Z Chen; Rossa W K Chiu; Attie T J I Go; Peiyong Jiang; Yongjie Jin; Yu Y Kung; Helena Lam; Elizabeth T Lau; Tze K Lau; Tak Y Leung; Wing C Leung; Fiona M F Lun; Ryoko Minekawa; Kypros H Nicolaides; Cees B M Oudejans; Hao Sun; Mary H Y Tang; Rebecca Y K Tang; William W K To; John M G van Vugt; Jun Wang; Xiuqing Zhang; Yama W L Zheng; Ranjit Akolekar; Sidney K C Au-Yeung; K C Allen Chan; Lisa Y S Chan; Y M Dennis Lo
Noninvasive prenatal diagnosis of fetal trisomy 18 and trisomy 13 by maternal plasma DNA sequencing.
PloS one 2011;6(7):e21791.
2011: Rossa W K Chiu; Ranjit Akolekar; Yama W L Zheng; Tak Y Leung; Hao Sun; K C Allen Chan; Fiona M F Lun; Attie T J I Go; Elizabeth T Lau; William W K To; Wing C Leung; Rebecca Y K Tang; Sidney K C Au-Yeung; Helena Lam; Yu Y Kung; Xiuqing Zhang; John M G van Vugt; Ryoko Minekawa; Mary H Y Tang; Jun Wang; Cees B M Oudejans; Tze K Lau; Kypros H Nicolaides; Y M Dennis Lo
Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study.
BMJ (Clinical research ed.) 2011;342():c7401.
2011: Gary J W Liao; Fiona M F Lun; Yama W L Zheng; K C Allen Chan; Tak Y Leung; Tze K Lau; Rossa W K Chiu; Y M Dennis Lo
Targeted massively parallel sequencing of maternal plasma DNA permits efficient and unbiased detection of fetal alleles.
Clinical chemistry 2011;57(1):92-101.
2010: Jie Xu; Xiang-Bo Wan; Xue-Fei Huang; K C Allen Chan; Ming-Huang Hong; Li-Hui Wang; Zi-Jie Long; Qing Liu; Min Yan; Y M Dennis Lo; Yi-Xin Zeng; Quentin Liu
Serologic antienzyme rate of Epstein-Barr virus DNase-specific neutralizing antibody segregates TNM classification in nasopharyngeal carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(35):5202-9.
2010: Y M Dennis Lo; K C Allen Chan; Hao Sun; Eric Z Chen; Peiyong Jiang; Fiona M F Lun; Yama W Zheng; Tak Y Leung; Tze K Lau; Charles R Cantor; Rossa W K Chiu
Maternal plasma DNA sequencing reveals the genome-wide genetic and mutational profile of the fetus.
Science translational medicine 2010;2(61):61ra91.
2010: Y M Dennis Lo; Rossa W K Chiu
Noninvasive approaches to prenatal diagnosis of hemoglobinopathies using fetal DNA in maternal plasma.
Hematology/oncology clinics of North America 2010;24(6):1179-86.
2010: Rossa W K Chiu; Y M Dennis Lo
Pregnancy-associated microRNAs in maternal plasma: a channel for fetal-maternal communication?
Clinical chemistry 2010;56(11):1656-7.
2010: Rossa W K Chiu; Hao Sun; Ranjit Akolekar; Christopher Clouser; Clarence Lee; Kevin McKernan; Daixing Zhou; Kypros H Nicolaides; Y M Dennis Lo
Maternal plasma DNA analysis with massively parallel sequencing by ligation for noninvasive prenatal diagnosis of trisomy 21.
Clinical chemistry 2010;56(3):459-63.
2010: Yu K Tong; Rossa W K Chiu; Ranjit Akolekar; Tak Y Leung; Tze K Lau; Kypros H Nicolaides; Y M Dennis Lo
Epigenetic-genetic chromosome dosage approach for fetal trisomy 21 detection using an autosomal genetic reference marker.
PloS one 2010;5(12):e15244.
2010: Dana W Y Tsui; Y M Doris Lam; Wing S Lee; Tak Y Leung; Tze K Lau; Elizabeth T Lau; Mary H Y Tang; Ranjit Akolekar; Kypros H Nicolaides; Rossa W K Chiu; Y M Dennis Lo; Stephen S C Chim
Systematic identification of placental epigenetic signatures for the noninvasive prenatal detection of Edwards syndrome.
PloS one 2010;5(11):e15069.
2010: Nancy B Y Tsui; Ranjit Akolekar; Rossa W K Chiu; Katherine C K Chow; Tak Y Leung; Tze K Lau; Kypros H Nicolaides; Y M Dennis Lo
Synergy of total PLAC4 RNA concentration and measurement of the RNA single-nucleotide polymorphism allelic ratio for the noninvasive prenatal detection of trisomy 21.
Clinical chemistry 2010;56(1):73-81.
2010: Yu K Tong; Shengnan Jin; Rossa W K Chiu; Chunming Ding; K C Allen Chan; Tak Y Leung; Ling Yu; Tze K Lau; Y M Dennis Lo
Noninvasive prenatal detection of trisomy 21 by an epigenetic-genetic chromosome-dosage approach.
Clinical chemistry 2010;56(1):90-8.
2010: Rebecca Wing-Yan Chan; John Wong; Henry L Y Chan; Tony Shu Kam Mok; Wyatt Y W Lo; Vincent Lee; Ka F To; Paul B S Lai; Timothy H Rainer; Y M Dennis Lo; Rossa W K Chiu
Aberrant concentrations of liver-derived plasma albumin mRNA in liver pathologies.
Clinical chemistry 2010;56(1):82-9.
2009: Nancy B Y Tsui; Blenda C K Wong; Tak Y Leung; Tze K Lau; Rossa W K Chiu; Y M Dennis Lo
Non-invasive prenatal detection of fetal trisomy 18 by RNA-SNP allelic ratio analysis using maternal plasma SERPINB2 mRNA: a feasibility study.
Prenatal diagnosis 2009;29(11):1031-7.
2009: Rossa W K Chiu; Charles R Cantor; Y M Dennis Lo
Non-invasive prenatal diagnosis by single molecule counting technologies.
Trends in genetics : TIG 2009;25(7):324-31.
2009: Winnie W I Pang; Michelle H Y Tsui; Daljit Sahota; Tak Y Leung; Tze K Lau; Y M Dennis Lo; Rossa W K Chiu
A strategy for identifying circulating placental RNA markers for fetal growth assessment.
Prenatal diagnosis 2009;29(5):495-504.
2009: Emily C W Hung; Rossa W K Chiu; Y M Dennis Lo
Detection of circulating fetal nucleic acids: a review of methods and applications.
Journal of clinical pathology 2009;62(4):308-13.
2009: Y M Dennis Lo; Carl T Wittwer
Molecular diagnostics: at the cutting edge of translational research.
Clinical chemistry 2009;55(4):601.
2009: Y M Dennis Lo; Rossa W K Chiu
Next-generation sequencing of plasma/serum DNA: an emerging research and molecular diagnostic tool.
Clinical chemistry 2009;55(4):607-8.
2009: Emily C W Hung; Tristan K F Shing; Stephen S C Chim; Philip C Yeung; Rebecca Wing-Yan Chan; Ki-Wai Chik; Vincent Lee; Nancy B Y Tsui; Chi kong Li; Cesar S C Wong; Rossa W K Chiu; Y M Dennis Lo
Presence of donor-derived DNA and cells in the urine of sex-mismatched hematopoietic stem cell transplant recipients: implication for the transrenal hypothesis.
Clinical chemistry 2009;55(4):715-22.
2009: Tony K F Yung; Allen Chan; Tony Shu Kam Mok; Joanna Tong; Ka-Fai To; Y M Dennis Lo
Single-molecule detection of epidermal growth factor receptor mutations in plasma by microfluidics digital PCR in non-small cell lung cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(6):2076-84.
2009: Macy M S Heung; Shengnan Jin; Nancy B Y Tsui; Chunming Ding; Tak Y Leung; Tze K Lau; Rossa W K Chiu; Y M Dennis Lo
Placenta-derived fetal specific mRNA is more readily detectable in maternal plasma than in whole blood.
PloS one 2009;4(6):e5858.
2008: Rossa W K Chiu; Allen Chan; Yuan Gao; Virginia Y M Lau; Wenli Zheng; Tak Yeung Leung; Chris H F Foo; Bin Xie; Nancy B Y Tsui; Fiona M F Lun; Benny Zee; tze lau; Charles R Cantor; Y M Dennis Lo
Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(51):20458-63.
2008: Brigette B Y Ma; Frankie Mo; Anthony T C Chan; Edwin P Hui; Sing-Fai Leung; Y M Dennis Lo; Yat Y Yau; Ann D King
The prognostic significance of tumor vascular invasion and its association with plasma Epstein-Barr virus DNA, tumor volume and metabolic activity in locoregionally advanced nasopharyngeal carcinoma.
Oral oncology 2008;44(11):1067-72.
2008: Allen Chan; Paul B S Lai; Tony Shu Kam Mok; Henry L Y Chan; Chunming Ding; S W Yeung; Y M Dennis Lo
Quantitative analysis of circulating methylated DNA as a biomarker for hepatocellular carcinoma.
Clinical chemistry 2008;54(9):1528-36.
2008: Y M Dennis Lo
Fetal nucleic acids in maternal plasma.
Annals of the New York Academy of Sciences 2008;1137():140-3.
2008: Allen Chan; Sing F Leung; Sze W Yeung; Anthony T C Chan; Y M Dennis Lo
Quantitative analysis of the transrenal excretion of circulating EBV DNA in nasopharyngeal carcinoma patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(15):4809-13.
2008: Allen Chan; Sing-Fai Leung; Sze-Wan Yeung; Anthony T C Chan; Y M Dennis Lo
Persistent aberrations in circulating DNA integrity after radiotherapy are associated with poor prognosis in nasopharyngeal carcinoma patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(13):4141-5.
2008: Brigette Ma; Edwin P Hui; Ann King; K F To; Frankie Mo; Sing F Leung; Michael Kam; Y M Dennis Lo; Benny Zee; Tony Shu Kam Mok; Anil Ahuja; Anthony T C Chan
A phase II study of patients with metastatic or locoregionally recurrent nasopharyngeal carcinoma and evaluation of plasma Epstein-Barr virus DNA as a biomarker of efficacy.
Cancer chemotherapy and pharmacology 2008;62(1):59-64.
2008: Stephen S C Chim; Tristan K F Shing; Emily C W Hung; Tak Yeung Leung; tze lau; Rossa W K Chiu; Y M Dennis Lo
Detection and characterization of placental microRNAs in maternal plasma.
Clinical chemistry 2008;54(3):482-90.
2008: Stephen S C Chim; Shengnan Jin; Tracy Y H Lee; Fiona M F Lun; Wing S Lee; Lisa Y S Chan; Yongjie Jin; Ningning Yang; Yu K Tong; Tak Y Leung; tze lau; Chunming Ding; Rossa W K Chiu; Y M Dennis Lo
Systematic search for placental DNA-methylation markers on chromosome 21: toward a maternal plasma-based epigenetic test for fetal trisomy 21.
Clinical chemistry 2008;54(3):500-11.
2008: Y M Dennis Lo; Rossa W K Chiu
Noninvasive prenatal diagnosis of fetal chromosomal aneuploidies by maternal plasma nucleic acid analysis.
Clinical chemistry 2008;54(3):461-6.
2008: Nancy B Y Tsui; Y M Dennis Lo
A microarray approach for systematic identification of placental-derived RNA markers in maternal plasma.
Methods in molecular biology (Clifton, N.J.) 2008;444():275-89.
2007: Dana W Y Tsui; Allen Chan; Stephen S C Chim; Lin Wai Chan; Tak Yeung Leung; tze lau; Y M Dennis Lo; Rossa W K Chiu
Quantitative aberrations of hypermethylated RASSF1A gene sequences in maternal plasma in pre-eclampsia.
Prenatal diagnosis 2007;27(13):1212-8.
2007: Jason C H Tsang; Pimlak Charoenkwan; Katherine C K Chow; Yongjie Jin; Chanane Wanapirak; Torpong Sanguansermsri; Y M Dennis Lo; Rossa W K Chiu
Mass spectrometry-based detection of hemoglobin E mutation by allele-specific base extension reaction.
Clinical chemistry 2007;53(12):2205-9.
2007: Yu K Tong; Rossa W K Chiu; Tak Y Leung; Chunming Ding; tze lau; Tse N Leung; Y M Dennis Lo
Detection of restriction enzyme-digested target DNA by PCR amplification using a stem-loop primer: application to the detection of hypomethylated fetal DNA in maternal plasma.
Clinical chemistry 2007;53(11):1906-14.
2007: Rebecca Wing-Yan Chan; Colin A Graham; Timothy H Rainer; Nicole Yuk Lan Lam; Rossa W K Chiu; Ki-Wai Chik; Vincent Lee; Y M Dennis Lo
Use of a bone marrow transplantation model system to demonstrate the hematopoietic origin of plasma S100B mRNA.
Clinical chemistry 2007;53(10):1874-6.
2007: Chun K Wong; Bonnie C K Wong; Allen Chan; Gavin M Joynt; Florence Y H Y Yap; Christopher W K Lam; Nelson Lee; Shui S Lee; Clive S Cockram; Joseph J Y Sung; Paul K S Chan; Y M Dennis Lo; Julian W Tang
Cytokine profile in fatal human immunodeficiency virus tuberculosis Epstein-Barr virus associated hemophagocytic syndrome.
Archives of internal medicine 2007;167(17):1901-3.
2007: Y M Dennis Lo; Fiona M F Lun; Allen Chan; Nancy B Y Tsui; Ka C Chong; tze lau; Tak Y Leung; Benny Zee; Charles R Cantor; Rossa W K Chiu
Digital PCR for the molecular detection of fetal chromosomal aneuploidy.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(32):13116-21.
2007: Y M Dennis Lo; Rossa W K Chiu
Non-invasive prenatal diagnosis of Down's syndrome.
Lancet 2007;369(9578):1997; author reply 1998-9.
2007: Nelson Tang; Paul K S Chan; David S C Hui; Ka-Fai To; Weimin Zhang; Francis K L Chan; Joseph Jao-Yiu Sung; Y M Dennis Lo
Lack of support for an association between CLEC4M homozygosity and protection against SARS coronavirus infection.
Nature genetics 2007;39(6):691-2; author reply 694-6.
2007: Jason C H Tsang; Y M Dennis Lo
Circulating nucleic acids in plasma/serum.
Pathology 2007;39(2):197-207.
2007: Fiona M F Lun; Rossa W K Chiu; Tak Y Leung; Tse N Leung; tze lau; Y M Dennis Lo
Epigenetic analysis of RASSF1A gene in cell-free DNA in amniotic fluid.
Clinical chemistry 2007;53(4):796-8.
2007: Allen Chan; Y M Dennis Lo
Circulating tumour-derived nucleic acids in cancer patients: potential applications as tumour markers.
British journal of cancer 2007;96(5):681-5.
2007: Rossa W K Chiu; Stephen S C Chim; Ivy H N Wong; Cesar S C Wong; Wing-Shan Lee; Ka-Fai To; Joanna H M Tong; Ryan Yuen; Alisa S W Shum; John K C Chan; Lisa Y S Chan; Jessie W F Yuen; Yu K Tong; Jingly F Weier; Christy Ferlatte; Tse N Leung; tze lau; Kwok-Wai Lo; Y M Dennis Lo
Hypermethylation of RASSF1A in human and rhesus placentas.
The American journal of pathology 2007;170(3):941-50.
2007: Y M Dennis Lo; Nancy B Y Tsui; Rossa W K Chiu; tze lau; Tse N Leung; Macy M S Heung; Ageliki Gerovassili; Yongjie Jin; Kypros H Nicolaides; Charles R Cantor; Chunming Ding
Plasma placental RNA allelic ratio permits noninvasive prenatal chromosomal aneuploidy detection.
Nature medicine 2007;13(2):218-23.
2007: Timothy H Rainer; Ka Sing Wong; Wynnie Lam; Nicole Y L Lam; Colin A Graham; Y M Dennis Lo
Comparison of plasma beta-globin DNA and S-100 protein concentrations in acute stroke.
Clinica chimica acta; international journal of clinical chemistry 2007;376(1-2):190-6.
2007: Katherine C K Chow; Rossa W K Chiu; Nancy B Y Tsui; Chunming Ding; tze lau; Tse N Leung; Y M Dennis Lo
Mass spectrometric detection of an SNP panel as an internal positive control for fetal DNA analysis in maternal plasma.
Clinical chemistry 2007;53(1):141-2.
2007: Lydia C W Lit; Chun Kwok Wong; Edmund K Li; Lai-Shan Tam; Christopher Wai-Kei Lam; Y M Dennis Lo
Elevated gene expression of Th1/Th2 associated transcription factors is correlated with disease activity in patients with systemic lupus erythematosus.
The Journal of rheumatology 2007;34(1):89-96.
2006: Sing-Fai Leung; Benny Zee; Brigette B Y Ma; Edwin P Hui; Frankie Mo; Maria Lai; Allen Chan; Lisa Y S Chan; Wing H Kwan; Y M Dennis Lo; Anthony T C Chan
Plasma Epstein-Barr viral deoxyribonucleic acid quantitation complements tumor-node-metastasis staging prognostication in nasopharyngeal carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(34):5414-8.
2006: Allen Chan; Chunming Ding; Ageliki Gerovassili; Sze W Yeung; Rossa W K Chiu; Tse N Leung; tze lau; Stephen S C Chim; Grace T Y Chung; Kypros H Nicolaides; Y M Dennis Lo
Hypermethylated RASSF1A in maternal plasma: A universal fetal DNA marker that improves the reliability of noninvasive prenatal diagnosis.
Clinical chemistry 2006;52(12):2211-8.
2006: Yu K Tong; Chunming Ding; Rossa W K Chiu; Ageliki Gerovassili; Stephen S C Chim; Tak Y Leung; Tse N Leung; tze lau; Kypros H Nicolaides; Y M Dennis Lo
Noninvasive prenatal detection of fetal trisomy 18 by epigenetic allelic ratio analysis in maternal plasma: Theoretical and empirical considerations.
Clinical chemistry 2006;52(12):2194-202.
2006: Brigette B Y Ma; Ann King; Y M Dennis Lo; Y Y Yau; Benny Zee; Edwin P Hui; Sing-Fai Leung; Frankie Mo; Michael K M Kam; Anil Ahuja; Wing H Kwan; Anthony T C Chan
Relationship between pretreatment level of plasma Epstein-Barr virus DNA, tumor burden, and metabolic activity in advanced nasopharyngeal carcinoma.
International journal of radiation oncology, biology, physics 2006;66(3):714-20.
2006: Chunming Ding; Y M Dennis Lo
MALDI-TOF mass spectrometry for quantitative, specific, and sensitive analysis of DNA and RNA.
Annals of the New York Academy of Sciences 2006;1075():282-7.
2006: Pang Ronald; Terence C W Poon; Allen Chan; Nelson L S Lee; Rossa W K Chiu; Yu K Tong; Stephen S C Chim; Joseph J Y Sung; Y M Dennis Lo
Serum amyloid A is not useful in the diagnosis of severe acute respiratory syndrome.
Clinical chemistry 2006;52(6):1202-4.
2006: T Partsalis; Louis Yik-Si Chan; M Hurworth; Craig Willers; Nathan J Pavlos; N Kumta; David Wood; Jiake Xu; Shekhar Kumta; Y M Dennis Lo; Ming H Zheng
Evidence of circulating donor genetic material in bone allotransplantation.
International journal of molecular medicine 2006;17(6):1151-5.
2006: Timothy H Rainer; Nicole Y L Lam; C Y Man; Rossa W K Chiu; K S Woo; Y M Dennis Lo
Plasma beta-globin DNA as a prognostic marker in chest pain patients.
Clinica chimica acta; international journal of clinical chemistry 2006;368(1-2):110-3.
2006: Blenda C K Wong; Allen Chan; Anthony T C Chan; Sing-Fai Leung; Lisa Y S Chan; Katherine C K Chow; Y M Dennis Lo
Reduced plasma RNA integrity in nasopharyngeal carcinoma patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(8):2512-6.
2006: S C C Wong; Anthony T C Chan; J K C Chan; Y M Dennis Lo
Nuclear beta-catenin and Ki-67 expression in choriocarcinoma and its pre-malignant form.
Journal of clinical pathology 2006;59(4):387-92.
2006: Y M Dennis Lo
Recent developments in fetal nucleic acids in maternal plasma: implications to noninvasive prenatal fetal blood group genotyping.
Transfusion clinique et biologique : journal de la Société française de transfusion sanguine 2006;13(1-2):50-2.
2006: Pang Ronald; Terence C W Poon; Allen Chan; Nelson L S Lee; Rossa W K Chiu; Yu K Tong; Ronald M Y Wong; Stephen S C Chim; Sai Ming Ngai; Joseph J Y Sung; Y M Dennis Lo
Serum proteomic fingerprints of adult patients with severe acute respiratory syndrome.
Clinical chemistry 2006;52(3):421-9.
2006: Rossa W K Chiu; Wing-Bong Lui; Mei-chun Cheung; Nihal Kumta; Antonio Farina; Irina Banzola; Silvia Grotti; Nicola Rizzo; Christopher J Haines; Y M Dennis Lo
Time profile of appearance and disappearance of circulating placenta-derived mRNA in maternal plasma.
Clinical chemistry 2006;52(2):313-6.
2006: Chunming Ding; Vincent Wong; Katherine C K Chow; Hoi-Yun Chan; Alex Yui Hui; Grace Lai-Hung Wong; Y M Dennis Lo; Joseph J Y Sung; Henry Lik-Yuen Chan
Quantitative subtyping of hepatitis B virus reveals complex dynamics of YMDD motif mutants development during long-term lamivudine therapy.
Antiviral therapy 2006;11(8):1041-9.
2006: Stephen S C Chim; Rossa W K Chiu; Y M Dennis Lo
Genomic sequencing of the severe acute respiratory syndrome-coronavirus.
Methods in molecular biology (Clifton, N.J.) 2006;336():177-94.
2006: Enders K.O. Ng; Y M Dennis Lo
Molecular diagnosis of severe acute respiratory syndrome.
Methods in molecular biology (Clifton, N.J.) 2006;336():163-75.
2006: Nancy B Y Tsui; Enders K.O. Ng; Y M Dennis Lo
Molecular analysis of circulating RNA in plasma.
Methods in molecular biology (Clifton, N.J.) 2006;336():123-34.
2006: Allen Chan; Y M Dennis Lo
Clinical applications of plasma Epstein-Barr virus DNA analysis and protocols for the quantitative analysis of the size of circulating Epstein-Barr virus DNA.
Methods in molecular biology (Clifton, N.J.) 2006;336():111-21.
2006: Rossa W K Chiu; Y M Dennis Lo
Noninvasive prenatal diagnosis by analysis of fetal DNA in maternal plasma.
Methods in molecular biology (Clifton, N.J.) 2006;336():101-9.
2006: Y M Dennis Lo; Allen Chan
Setting up a polymerase chain reaction laboratory.
Methods in molecular biology (Clifton, N.J.) 2006;336():11-8.
2006: Y M Dennis Lo; Allen Chan
Introduction to the polymerase chain reaction.
Methods in molecular biology (Clifton, N.J.) 2006;336():1-10.
2006: Yu K Tong; Y M Dennis Lo
Plasma epigenetic markers for cancer detection and prenatal diagnosis.
Frontiers in bioscience : a journal and virtual library 2006;11():2647-56.
2006: Nicole Y L Lam; Timothy H Rainer; Lawrence K S Wong; Wynnie Lam; Y M Dennis Lo
Plasma DNA as a prognostic marker for stroke patients with negative neuroimaging within the first 24 h of symptom onset.
Resuscitation 2006;68(1):71-8.
2006: Yu K Tong; Y M Dennis Lo
Diagnostic developments involving cell-free (circulating) nucleic acids.
Clinica chimica acta; international journal of clinical chemistry 2006;363(1-2):187-96.
2005: Allen Chan; Angela Bik-Yu Hui; Nathalie Wong; tze lau; Tse N Leung; Kwok-Wai Lo; Y M Dennis Lo
Investigation of the genomic representation of plasma DNA in pregnant women by comparative genomic hybridization analysis: a feasibility study.
Clinical chemistry 2005;51(12):2398-401.
2005: Nancy B Y Tsui; Rossa W K Chiu; Chunming Ding; Ahmad El-Sheikhah; Tse N Leung; tze lau; Kypros H Nicolaides; Y M Dennis Lo
Detection of trisomy 21 by quantitative mass spectrometric analysis of single-nucleotide polymorphisms.
Clinical chemistry 2005;51(12):2358-62.
2005: Rossa W K Chiu; Carol W M Chan; Xiao Yan Zhong; Olav Lapaire; Wolfgang Holzgreve; Sinuhe Hahn; Y M Dennis Lo
Fetal rhesus D mRNA is not detectable in maternal plasma.
Clinical chemistry 2005;51(11):2210-1.
2005: Rossa W K Chiu; Wing-Bong Lui; Ahmad El-Sheikhah; Anthony T C Chan; tze lau; Kypros H Nicolaides; Y M Dennis Lo
Comparison of protocols for extracting circulating DNA and RNA from maternal plasma.
Clinical chemistry 2005;51(11):2209-10.
2005: Allen Chan; Anthony T C Chan; Sing-Fai Leung; Jesse C S Pang; Angela Yee-Moon Wang; Joanna H M Tong; Ka-Fai To; Lisa Y S Chan; Lisa L S Tam; Nellie Yuk-Fei Chung; Jun Zhang; Kwok-Wai Lo; Dolly P Huang; Y M Dennis Lo
Investigation into the origin and tumoral mass correlation of plasma Epstein-Barr virus DNA in nasopharyngeal carcinoma.
Clinical chemistry 2005;51(11):2192-5.
2005: Stephen S C Chim; Yu K Tong; Rossa W K Chiu; tze lau; Tse N Leung; Lisa Y S Chan; Cees B M Oudejans; Chunming Ding; Y M Dennis Lo
Detection of the placental epigenetic signature of the maspin gene in maternal plasma.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(41):14753-8.
2005: Blenda C K Wong; Rossa W K Chiu; Nancy B Y Tsui; Allen Chan; Lin W Chan; tze lau; Tse N Leung; Y M Dennis Lo
Circulating placental RNA in maternal plasma is associated with a preponderance of 5' mRNA fragments: implications for noninvasive prenatal diagnosis and monitoring.
Clinical chemistry 2005;51(10):1786-95.
2005: S C C Wong; Anthony T C Chan; E S F Lo; Y M Dennis Lo
Nuclear beta-catenin expression is rare and its potential association with short survival in colorectal signet-ring cell carcinoma.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2005;13(3):248-51.
2005: Stefan Holdenrieder; Petra Stieber; Lisa Y S Chan; Sandra Geiger; Andreas E. Kremer; Dorothea Nagel; Y M Dennis Lo
Cell-free DNA in serum and plasma: comparison of ELISA and quantitative PCR.
Clinical chemistry 2005;51(8):1544-6.
2005: Patrick T W Law; CHI HANG WONG; Thomas C C Au; Chi-Pang Chuck; Siu-Kai Kong; Paul K S Chan; Ka-Fai To; Anthony W I Lo; Judy Y W Chan; Yick-Keung Suen; H Y Edwin Chan; Kwok-Pui Fung; Mary Waye; Joseph J Y Sung; Y M Dennis Lo; Stephen Kwok-Wing Tsui
The 3a protein of severe acute respiratory syndrome-associated coronavirus induces apoptosis in Vero E6 cells.
The Journal of general virology 2005;86(Pt 7):1921-30.
2005: Frankie W T Cheng; Enders K.O. Ng; Albert M Li; Ellis K L Hon; Allen Chan; Y M Dennis Lo; Pak C Ng
Clinical, virologic and immunologic profiles of a young infant with severe acute respiratory syndrome.
The Pediatric infectious disease journal 2005;24(6):567-8.
2005: Grace T Y Chung; Rossa W K Chiu; Allen Chan; tze lau; Tse N Leung; Lin W Chan; Y M Dennis Lo
Detrimental effect of formaldehyde on plasma RNA detection.
Clinical chemistry 2005;51(6):1074-6.
2005: Allen Chan; Sze-Wan Yeung; Wing-Bong Lui; Timothy H Rainer; Y M Dennis Lo
Effects of preanalytical factors on the molecular size of cell-free DNA in blood.
Clinical chemistry 2005;51(4):781-4.
2005: Y M Dennis Lo
Recent advances in fetal nucleic acids in maternal plasma.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005;53(3):293-6.
2005: Grace T Y Chung; Rossa W K Chiu; Allen Chan; tze lau; Tse N Leung; Y M Dennis Lo
Lack of dramatic enrichment of fetal DNA in maternal plasma by formaldehyde treatment.
Clinical chemistry 2005;51(3):655-8.
2005: Thomas Gingeras; Russell Higuchi; Larry J Kricka; Y M Dennis Lo; Carl T Wittwer
Fifty years of molecular (DNA/RNA) diagnostics.
Clinical chemistry 2005;51(3):661-71.
2005: Rossa W K Chiu; Timothy H Rainer; Y M Dennis Lo
Circulating nucleic acid analysis: diagnostic applications for acute pathologies.
Acta neurochirurgica. Supplement 2005;95():471-4.
2005: Grace T Y Chung; Rossa W K Chiu; Jo L K Cheung; Yongjie Jin; Stephen S C Chim; Paul K S Chan; Y M Dennis Lo
A simple and rapid approach for screening of SARS-coronavirus genotypes: an evaluation study.
BMC infectious diseases 2005;5():87.
2005: Allen Chan; Nelson Tang; David S C Hui; Grace T Y Chung; A K L Wu; Stephen S C Chim; Rossa W K Chiu; Nelson Lee; Kin Wing CHOI; Ying-Man Sung; Paul K S Chan; Yu K Tong; Sik-To Lai; Wai-Cho Yu; Owen T Y Tsang; Y M Dennis Lo
Absence of association between angiotensin converting enzyme polymorphism and development of adult respiratory distress syndrome in patients with severe acute respiratory syndrome: a case control study.
BMC infectious diseases 2005;5():26.
2005: Rossa W K Chiu; Stephen S C Chim; Yu K Tong; Kitty S C Fung; Paul K S Chan; Guo-ping Zhao; Y M Dennis Lo
Tracing SARS-coronavirus variant with large genomic deletion.
Emerging infectious diseases 2005;11(1):168-70.
2004: Y M Dennis Lo; Rossa W K Chiu; Allen Chan; Grace T Y Chung
Free fetal DNA in maternal circulation.
JAMA : the journal of the American Medical Association 2004;292(23):2835; author reply 2835-6.
2004: Nelson Lee; K C Allen Chan; David S C Hui; Enders K.O. Ng; Alan Wu; Allen Chan; Vincent Wong; Paul K S Chan; Ka Tak Wong; Eric Wong; Clive S Cockram; John S Tam; Joseph J Y Sung; Y M Dennis Lo
Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2004;31(4):304-9.
2004: Antonio Farina; Carol W M Chan; Rossa W K Chiu; Nancy B Y Tsui; Paolo Carinci; Manuela Concu; Irina Banzola; Nicola Rizzo; Y M Dennis Lo
Circulating corticotropin-releasing hormone mRNA in maternal plasma: relationship with gestational age and severity of preeclampsia.
Clinical chemistry 2004;50(10):1851-4.
2004: Lydia C W Lit; Allen Chan; Sing-Fai Leung; Kenny I K Lei; Lisa Y S Chan; Katherine C K Chow; Anthony T C Chan; Y M Dennis Lo
Distribution of cell-free and cell-associated Epstein-Barr virus (EBV) DNA in the blood of patients with nasopharyngeal carcinoma and EBV-associated lymphoma.
Clinical chemistry 2004;50(10):1842-5.
2004: Rossa W K Chiu; Nelson Tang; David S C Hui; Grace T Y Chung; Stephen S C Chim; Allen Chan; Ying-Man Sung; Louis Y S Chan; Yu K Tong; Wing-shan Lee; Paul K S Chan; Y M Dennis Lo
ACE2 gene polymorphisms do not affect outcome of severe acute respiratory syndrome.
Clinical chemistry 2004;50(9):1683-6.
2004: Anthony T C Chan; Brigette B Y Ma; Y M Dennis Lo; Sing-Fai Leung; Wing H Kwan; Edwin P Hui; Tony Shu Kam Mok; Michael K M Kam; Lisa S Chan; Samuel K W Chiu; Kwok Hung Yu; Kin-yin Cheung; Karen Lai; Maria Lai; Frankie Mo; Winnie Yeo; Ann King; Philip J Johnson; Peter M L Teo; Benny Zee
Phase II study of neoadjuvant carboplatin and paclitaxel followed by radiotherapy and concurrent cisplatin in patients with locoregionally advanced nasopharyngeal carcinoma: therapeutic monitoring with plasma Epstein-Barr virus DNA.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(15):3053-60.
2004: Terence C W Poon; Allen Chan; Pak C Ng; Rossa W K Chiu; Irene L Ang; Yu K Tong; Enders K.O. Ng; Frankie W T Cheng; Albert M Li; Ellis K L Hon; Tai Fai Fok; Y M Dennis Lo
Serial analysis of plasma proteomic signatures in pediatric patients with severe acute respiratory syndrome and correlation with viral load.
Clinical chemistry 2004;50(8):1452-5.
2004: Chunming Ding; Rossa W K Chiu; tze lau; Tse N Leung; Li C Chan; Amy Y Y Chan; Pimlak Charoenkwan; Ivy S L Ng; Hai-Yang Law; Edmond S K Ma; Xiangmin Xu; Chanane Wanapirak; Torpong Sanguansermsri; Can Liao; Mary Anne Tan Jin Ai; David H K Chui; Charles R Cantor; Y M Dennis Lo
MS analysis of single-nucleotide differences in circulating nucleic acids: Application to noninvasive prenatal diagnosis.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(29):10762-7.
2004: Y M Dennis Lo; Rossa W K Chiu
The biology and diagnostic applications of plasma RNA.
Annals of the New York Academy of Sciences 2004;1022():135-9.
2004: Rossa W K Chiu; Y M Dennis Lo
Recent developments in fetal DNA in maternal plasma.
Annals of the New York Academy of Sciences 2004;1022():100-4.
2004: N B Y Tsui; Stephen S C Chim; Rossa W K Chiu; tze lau; Enders K.O. Ng; T N Leung; Yu K Tong; Allen Chan; Y M Dennis Lo
Systematic micro-array based identification of placental mRNA in maternal plasma: towards non-invasive prenatal gene expression profiling.
Journal of medical genetics 2004;41(6):461-7.
2004: Enders K.O. Ng; Ahmad El-Sheikhah; Rossa W K Chiu; Allen Chan; Matthew Hogg; Renu Bindra; Tse N Leung; tze lau; Kypros H Nicolaides; Y M Dennis Lo
Evaluation of human chorionic gonadotropin beta-subunit mRNA concentrations in maternal serum in aneuploid pregnancies: a feasibility study.
Clinical chemistry 2004;50(6):1055-7.
2004: Wai-Yan Choy; Shu-Guang Lin; Paul K S Chan; John S Tam; Y M Dennis Lo; Ida M T Chu; Sau-Na Tsai; Ming-Qi Zhong; Kwok-Pui Fung; Mary Waye; Stephen Kwok-Wing Tsui; Enders K.O. Ng; Zhi-xin Shan; Min Yang; Yi-Long Wu; Zhan-Yi Lin; Sai Ming Ngai
Synthetic peptide studies on the severe acute respiratory syndrome (SARS) coronavirus spike glycoprotein: perspective for SARS vaccine development.
Clinical chemistry 2004;50(6):1036-42.
2004: Stephen S C Chim; Y M Dennis Lo
Molecular epidemiology of the coronavirus associated with severe acute respiratory syndrome: a review of data from the Chinese University of Hong Kong.
The Clinical biochemist. Reviews / Australian Association of Clinical Biochemists 2004;25(2):143-7.
2004: Shira Gal; Carrie Fidler; Y M Dennis Lo; M Taylor; Cheng Han; J Moore; Adrian L Harris; james wainscoat
Quantitation of circulating DNA in the serum of breast cancer patients by real-time PCR.
British journal of cancer 2004;90(6):1211-5.
2004: Kwok Hung Yu; Y M Dennis Lo; Gary M K Tse; Allen Chan; Amy B W Chan; Katherine C K Chow; Tony K F Ma; Alexander C Vlantis; Sing-Fai Leung; C Andrew van Hasselt; Philip J Johnson; Anthony T C Chan
Quantitative analysis of cell-free Epstein-Barr virus DNA in plasma of patients with nonnasopharyngeal head and neck carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(5):1726-32.
2004: Sze Chuen Cesar Wong; Siu Fong Elena Lo; Moon-Tong Cheung; Enders K.O. Ng; Cindy W S Tse; Bo San Paul Lai; King Chung Lee; Y M Dennis Lo
Quantification of plasma beta-catenin mRNA in colorectal cancer and adenoma patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(5):1613-7.
2004: Ka-Fai To; Joanna H M Tong; Paul K S Chan; Florence W L Au; Stephen S C Chim; Allen Chan; Jo L K Cheung; Esther Y M Liu; Gary M K Tse; Anthony W I Lo; Y M Dennis Lo; Ho-Keung Ng
Tissue and cellular tropism of the coronavirus associated with severe acute respiratory syndrome: an in-situ hybridization study of fatal cases.
The Journal of pathology 2004;202(2):157-63.
2004: Sing-Fai Leung; John S Tam; Anthony T C Chan; Benny Zee; Lisa Y S Chan; Dolly P Huang; Andrew C van Hasselt; Philip J Johnson; Y M Dennis Lo
Improved accuracy of detection of nasopharyngeal carcinoma by combined application of circulating Epstein-Barr virus DNA and anti-Epstein-Barr viral capsid antigen IgA antibody.
Clinical chemistry 2004;50(2):339-45.
2004: Rossa W K Chiu; Y M Dennis Lo
The biology and diagnostic applications of fetal DNA and RNA in maternal plasma.
Current topics in developmental biology 2004;61():81-111.
2004: Allen Chan; Y M Dennis Lo
Circulating DNA analysis: protocols and clinical applications using TaqMan assays.
Methods in molecular medicine 2004;97():217-36.
2004: Nicole Y L Lam; Timothy H Rainer; Rossa W K Chiu; Y M Dennis Lo
EDTA is a better anticoagulant than heparin or citrate for delayed blood processing for plasma DNA analysis.
Clinical chemistry 2004;50(1):256-7.
2004: Stephen S C Chim; Yu K Tong; Emily C W Hung; Rossa W K Chiu; Y M Dennis Lo
Genomic sequencing of a SARS coronavirus isolate that predated the Metropole Hotel case cluster in Hong Kong.
Clinical chemistry 2004;50(1):231-3.
2004: Nicole Y L Lam; Timothy H Rainer; Rossa W K Chiu; Gavin M Joynt; Y M Dennis Lo
Plasma mitochondrial DNA concentrations after trauma.
Clinical chemistry 2004;50(1):213-6.
2004: Timothy H Rainer; Nicole Y L Lam; Nancy B Y Tsui; Enders K.O. Ng; Rossa W K Chiu; Gavin M Joynt; Y M Dennis Lo
Effects of filtration on glyceraldehyde-3-phosphate dehydrogenase mRNA in the plasma of trauma patients and healthy individuals.
Clinical chemistry 2004;50(1):206-8.
2004: Allen Chan; Jun Zhang; Angela Bik-Yu Hui; Nathalie Wong; tze lau; Tse N Leung; Kwok-Wai Lo; Dolly W S Huang; Y M Dennis Lo
Size distributions of maternal and fetal DNA in maternal plasma.
Clinical chemistry 2004;50(1):88-92.
2003: Emily C W Hung; Stephen S C Chim; Paul K S Chan; Yu K Tong; Enders K.O. Ng; Rossa W K Chiu; Chi-Bon Leung; Joseph J Y Sung; John S Tam; Y M Dennis Lo
Detection of SARS coronavirus RNA in the cerebrospinal fluid of a patient with severe acute respiratory syndrome.
Clinical chemistry 2003;49(12):2108-9.
2003: Enders K.O. Ng; Pak C Ng; K L E Hon; Wai Tsoi Frankie Cheng; Emily C W Hung; Allen Chan; Rossa W K Chiu; Albert M Li; Leo Poon; David S C Hui; John S Tam; Tai Fai Fok; Y M Dennis Lo
Serial analysis of the plasma concentration of SARS coronavirus RNA in pediatric patients with severe acute respiratory syndrome.
Clinical chemistry 2003;49(12):2085-8.
2003: Enders K.O. Ng; David S C Hui; Allen Chan; Emily C W Hung; Rossa W K Chiu; Nelson Lee; Alan Wu; Stephen S C Chim; Yu K Tong; Joseph J Y Sung; John S Tam; Y M Dennis Lo
Quantitative analysis and prognostic implication of SARS coronavirus RNA in the plasma and serum of patients with severe acute respiratory syndrome.
Clinical chemistry 2003;49(12):1976-80.
2003: Leo Poon; Kwok-Hung Chan; On Kei Wong; Wing-Cheong Yam; Kwok-Yung Yuen; Yi Guan; Y M Dennis Lo; J S M Peiris
Early diagnosis of SARS coronavirus infection by real time RT-PCR.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2003;28(3):233-8.
2003: Stephen S C Chim; Stephen Kwok-Wing Tsui; Allen Chan; Thomas C C Au; Emily C W Hung; Yu K Tong; Rossa W K Chiu; Enders K.O. Ng; Paul K S Chan; C M Chu; J J Y Sung; John S Tam; Kwok-Pui Fung; Mary Waye; C Y Lee; K Y Yuen; Y M Dennis Lo
Genomic characterisation of the severe acute respiratory syndrome coronavirus of Amoy Gardens outbreak in Hong Kong.
Lancet 2003;362(9398):1807-8.
2003: Rossa W K Chiu; Stephen S C Chim; Y M Dennis Lo
Molecular epidemiology of SARS--from Amoy Gardens to Taiwan.
The New England journal of medicine 2003;349(19):1875-6.
2003: Blenda C K Wong; Y M Dennis Lo
Cell-free DNA and RNA in plasma as new tools for molecular diagnostics.
Expert review of molecular diagnostics 2003;3(6):785-97.
2003: Sing-Fai Leung; Y M Dennis Lo; Anthony T C Chan; Kai-Fai To; Edward To; Lisa Y S Chan; Benny Zee; Dolly P Huang; Philip J Johnson
Disparity of sensitivities in detection of radiation-naïve and postirradiation recurrent nasopharyngeal carcinoma of the undifferentiated type by quantitative analysis of circulating Epstein-Barr virus DNA1,2.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(9):3431-4.
2003: Edward W H To; Allen Chan; Sing-Fai Leung; Lisa Y S Chan; Ka-Fai To; Anthony T C Chan; Philip J Johnson; Y M Dennis Lo
Rapid clearance of plasma Epstein-Barr virus DNA after surgical treatment of nasopharyngeal carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(9):3254-9.
2003: Nicole Y L Lam; Timothy H Rainer; Lisa Y S Chan; Gavin M Joynt; Y M Dennis Lo
Time course of early and late changes in plasma DNA in trauma patients.
Clinical chemistry 2003;49(8):1286-91.
2003: Sing-Fai Leung; Anthony T C Chan; Benny Zee; Brigette Ma; Lisa Y S Chan; Philip J Johnson; Y M Dennis Lo
Pretherapy quantitative measurement of circulating Epstein-Barr virus DNA is predictive of posttherapy distant failure in patients with early-stage nasopharyngeal carcinoma of undifferentiated type.
Cancer 2003;98(2):288-91.
2003: Stephen Kwok-Wing Tsui; Stephen S C Chim; Y M Dennis Lo
Coronavirus genomic-sequence variations and the epidemiology of the severe acute respiratory syndrome.
The New England journal of medicine 2003;349(2):187-8.
2003: Allen Chan; Jun Zhang; Anthony T C Chan; Kenny I K Lei; Sing-Fai Leung; Lisa Y S Chan; Katherine C K Chow; Y M Dennis Lo
Molecular characterization of circulating EBV DNA in the plasma of nasopharyngeal carcinoma and lymphoma patients.
Cancer research 2003;63(9):2028-32.
2003: Michael H M Chan; Kai Ming Chow; Anthony T C Chan; Chi-Bon Leung; Lisa Y S Chan; Katherine C K Chow; Ching-Wan Lam; Y M Dennis Lo
Quantitative analysis of pleural fluid cell-free DNA as a tool for the classification of pleural effusions.
Clinical chemistry 2003;49(5):740-5.
2003: Enders K.O. Ng; Tse N Leung; Nancy B Y Tsui; tze lau; Nirmal S Panesar; Rossa W K Chiu; Y M Dennis Lo
The concentration of circulating corticotropin-releasing hormone mRNA in maternal plasma is increased in preeclampsia.
Clinical chemistry 2003;49(5):727-31.
2003: Rossa W K Chiu; Lisa Y S Chan; Nicole Y L Lam; Nancy B Y Tsui; Enders K.O. Ng; Timothy H Rainer; Y M Dennis Lo
Quantitative analysis of circulating mitochondrial DNA in plasma.
Clinical chemistry 2003;49(5):719-26.
2003: Enders K.O. Ng; Nancy B Y Tsui; tze lau; Tse N Leung; Rossa W K Chiu; Nirmal S Panesar; Lydia C W Lit; Kam-Wing Chan; Y M Dennis Lo
mRNA of placental origin is readily detectable in maternal plasma.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(8):4748-53.
2003: Lisa Y S Chan; Tse N Leung; Allen Chan; Hok-Leung Tai; tze lau; Eric M C Wong; Y M Dennis Lo
Serial analysis of fetal DNA concentrations in maternal plasma in late pregnancy.
Clinical chemistry 2003;49(4):678-80.
2003: Timothy H Rainer; Lawrence K S Wong; Wynnie Lam; Eddie Yuen; Nicole Y L Lam; Constantine Metreweli; Y M Dennis Lo
Prognostic use of circulating plasma nucleic acid concentrations in patients with acute stroke.
Clinical chemistry 2003;49(4):562-9.
2003: Allen K C Chan; Allen Chan; Y M Dennis Lo
Cell-free nucleic acids in plasma, serum and urine: a new tool in molecular diagnosis.
Annals of clinical biochemistry 2003;40(Pt 2):122-30.
2003: Ivy H N Wong; Jun Zhang; Paul B S Lai; Wan Y Lau; Y M Dennis Lo
Quantitative analysis of tumor-derived methylated p16INK4a sequences in plasma, serum, and blood cells of hepatocellular carcinoma patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(3):1047-52.
2003: Rossa W K Chiu; Y M Dennis Lo
Non-invasive prenatal diagnosis: on the horizon?
Pharmacogenomics 2003;4(2):191-200.
2003: Yanni Y N Lui; Kam-Sang Woo; Angela Yee-Moon Wang; Chung-Kwong Yeung; Philip K T Li; Elaine Chau; Peter N Ruygrok; Y M Dennis Lo
Origin of plasma cell-free DNA after solid organ transplantation.
Clinical chemistry 2003;49(3):495-6.
2003: Y M Dennis Lo; Leo Poon
The ins and outs of fetal DNA in maternal plasma.
Lancet 2003;361(9353):193-4.
2003: Y M Dennis Lo
Fetal DNA in maternal plasma/serum: the first 5 years.
Pediatric research 2003;53(1):16-7.
2003: Robert Angert; Erik S LeShane; Y M Dennis Lo; Lisa Y S Chan; Laurent C Delli-Bovi; Diana Bianchi
Fetal cell-free plasma DNA concentrations in maternal blood are stable 24 hours after collection: analysis of first- and third-trimester samples.
Clinical chemistry 2003;49(1):195-8.
2002: Allen Chan; Y M Dennis Lo
Circulating EBV DNA as a tumor marker for nasopharyngeal carcinoma.
Seminars in cancer biology 2002;12(6):489-96.
2002: Tai-Wah Lau; Tse N Leung; Lisa Y S Chan; tze lau; Allen Chan; Wing H Tam; Y M Dennis Lo
Fetal DNA clearance from maternal plasma is impaired in preeclampsia.
Clinical chemistry 2002;48(12):2141-6.
2002: Anthony T C Chan; Y M Dennis Lo; Benny Zee; Lisa Y S Chan; Brigette B Y Ma; Sing-Fai Leung; Frankie Mo; Maria Lai; Stephen Ho; Dolly P Huang; Philip J Johnson
Plasma Epstein-Barr virus DNA and residual disease after radiotherapy for undifferentiated nasopharyngeal carcinoma.
Journal of the National Cancer Institute 2002;94(21):1614-9.
2002: Martin Wai Pak; Ka-Fai To; Y M Dennis Lo; Lisa Y S Chan; J H M Tong; Kwok Wai Lo; C Andrew van Hasselt
Nasopharyngeal carcinoma in situ (NPCIS)--pathologic and clinical perspectives.
Head & neck 2002;24(11):989-95.
2002: Yanni Y N Lui; Ki-Wai Chik; Y M Dennis Lo
Does centrifugation cause the ex vivo release of DNA from blood cells?
Clinical chemistry 2002;48(11):2074-6.
2002: Ivy H N Wong; Y M Dennis Lo
New markers for cancer detection.
Current oncology reports 2002;4(6):471-7.
2002: Nathalie C Lambert; Y M Dennis Lo; Timothy D Erickson; Tracy S Tylee; Katherine A Guthrie; Daniel E Furst; J Lee Nelson
Male microchimerism in healthy women and women with scleroderma: cells or circulating DNA? A quantitative answer.
Blood 2002;100(8):2845-51.
2002: Nancy B Y Tsui; Enders K.O. Ng; Y M Dennis Lo
Stability of endogenous and added RNA in blood specimens, serum, and plasma.
Clinical chemistry 2002;48(10):1647-53.
2002: Rossa W K Chiu; tze lau; Tse N Leung; Katherine C K Chow; David H K Chui; Y M Dennis Lo
Prenatal exclusion of beta thalassaemia major by examination of maternal plasma.
Lancet 2002;360(9338):998-1000.
2002: Enders K.O. Ng; Nancy B Y Tsui; Nicole Y L Lam; Rossa W K Chiu; Simon C H Yu; S C Cesar Wong; Elena S F Lo; Timothy H Rainer; Philip J Johnson; Y M Dennis Lo
Presence of filterable and nonfilterable mRNA in the plasma of cancer patients and healthy individuals.
Clinical chemistry 2002;48(8):1212-7.
2002: Philip J Johnson; Y M Dennis Lo
Plasma nucleic acids in the diagnosis and management of malignant disease.
Clinical chemistry 2002;48(8):1186-93.
2002: Rossa W K Chiu; tze lau; Pik T Cheung; Zhi Q Gong; Tse N Leung; Y M Dennis Lo
Noninvasive prenatal exclusion of congenital adrenal hyperplasia by maternal plasma analysis: a feasibility study.
Clinical chemistry 2002;48(5):778-80.
2002: Sheng Zhong; Mandy W Tang; Winnie Yeo; Cuiling Liu; Y M Dennis Lo; Philip J Johnson
Silencing of GSTP1 gene by CpG island DNA hypermethylation in HBV-associated hepatocellular carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(4):1087-92.
2002: Yanni Y N Lui; Ki-Wai Chik; Rossa W K Chiu; Cheong-Yip Ho; Christopher W K Lam; Y M Dennis Lo
Predominant hematopoietic origin of cell-free DNA in plasma and serum after sex-mismatched bone marrow transplantation.
Clinical chemistry 2002;48(3):421-7.
2002: Allen Chan; Y M Dennis Lo
Circulating nucleic acids as a tumor marker.
Histology and histopathology 2002;17(3):937-43.
2002: Rossa W K Chiu; Y M Dennis Lo
Application of fetal DNA in maternal plasma for noninvasive prenatal diagnosis.
Expert review of molecular diagnostics 2002;2(1):32-40.
2002: Kenny I K Lei; Lisa Y S Chan; Wing-Yee Chan; Philip J Johnson; Y M Dennis Lo
Diagnostic and prognostic implications of circulating cell-free Epstein-Barr virus DNA in natural killer/T-cell lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(1):29-34.
2002: Leo Poon; Tse N Leung; tze lau; Katherine C K Chow; Y M Dennis Lo
Differential DNA methylation between fetus and mother as a strategy for detecting fetal DNA in maternal plasma.
Clinical chemistry 2002;48(1):35-41.
2001: L L Poon; Y M Dennis Lo
Circulating fetal DNA in maternal plasma.
Clinica chimica acta; international journal of clinical chemistry 2001;313(1-2):151-5.
2001: K I Lei; Lisa Y S Chan; W Y Chan; Philip J Johnson; Y M Dennis Lo
Circulating cell-free Epstein-Barr virus DNA levels in patients with EBV-associated lymphoid malignancies.
Annals of the New York Academy of Sciences 2001;945():80-3.
2001: Ivy H N Wong; Y M Dennis Lo; P J Johnson
Epigenetic tumor markers in plasma and serum: biology and applications to molecular diagnosis and disease monitoring.
Annals of the New York Academy of Sciences 2001;945():36-50.
2001: Shira Gal; Carrie Fidler; S Turner; Y M Dennis Lo; D J Roberts; james wainscoat
Detection of Plasmodium falciparum DNA in plasma.
Annals of the New York Academy of Sciences 2001;945():234-8.
2001: Timothy H Rainer; Y M Dennis Lo; Lisa Y S Chan; Nicole Y L Lam; L C Lit; Robert A Cocks
Derivation of a prediction rule for posttraumatic organ failure using plasma DNA and other variables.
Annals of the New York Academy of Sciences 2001;945():211-20.
2001: Leo Poon; T N Leung; tze lau; Y M Dennis Lo
Circulating fetal RNA in maternal plasma.
Annals of the New York Academy of Sciences 2001;945():207-10.
2001: Shira Gal; Carrie Fidler; Y M Dennis Lo; K Chin; J Moore; Adrian L Harris; james wainscoat
Detection of mammaglobin mRNA in the plasma of breast cancer patients.
Annals of the New York Academy of Sciences 2001;945():192-4.
2001: Rossa W K Chiu; M F Murphy; Carrie Fidler; james wainscoat; Y M Dennis Lo
Technical optimization of RhD zygosity determination by real-time quantitative polymerase chain reaction: implication for fetal RhD status determination by maternal plasma.
Annals of the New York Academy of Sciences 2001;945():156-60.
2001: Rossa W K Chiu; Leo Poon; tze lau; Tse N Leung; Eric M C Wong; Y M Dennis Lo
Effects of blood-processing protocols on fetal and total DNA quantification in maternal plasma.
Clinical chemistry 2001;47(9):1607-13.
2001: Y M Dennis Lo; W Y Chan; Enders Ng; Lisa Y S Chan; P B Lai; J S Tam; S C Chung
Circulating Epstein-Barr virus DNA in the serum of patients with gastric carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(7):1856-9.
2000: Y M Dennis Lo; Anthony T C Chan; Lisa Y S Chan; Sing-Fai Leung; C W Lam; Dolly P Huang; PJ Johnson
Molecular prognostication of nasopharyngeal carcinoma by quantitative analysis of circulating Epstein-Barr virus DNA.
Cancer research 2000;60(24):6878-81.
2000: Ching-Wan Lam; Wai Lan Yeung; C H Ko; Priscilla M K Poon; Sui-Fan Tong; K Y Chan; I F Lo; L Y Chan; J Hui; V Wong; Chi Pui Pang; Y M Dennis Lo; T F Fok
Spectrum of mutations in the MECP2 gene in patients with infantile autism and Rett syndrome.
Journal of medical genetics 2000;37(12):E41.
2000: Y M Dennis Lo
Fetal DNA in maternal plasma: biology and diagnostic applications.
Clinical chemistry 2000;46(12):1903-6.
2000: Leo Poon; Tse N Leung; tze lau; Y M Dennis Lo
Presence of fetal RNA in maternal plasma.
Clinical chemistry 2000;46(11):1832-4.
2000: K I Lei; Lisa Y S Chan; W Y Chan; P J Johnson; Y M Dennis Lo
Quantitative analysis of circulating cell-free Epstein-Barr virus (EBV) DNA levels in patients with EBV-associated lymphoid malignancies.
British journal of haematology 2000;111(1):239-46.
2000: IH Wong; Y M Dennis Lo; W Yeo; WY Lau; Philip J Johnson
Frequent p15 promoter methylation in tumor and peripheral blood from hepatocellular carcinoma patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(9):3516-21.
2000: Y M Dennis Lo; tze lau; L Y Chan; Tse N Leung; A M Chang
Quantitative analysis of the bidirectional fetomaternal transfer of nucleated cells and plasma DNA.
Clinical chemistry 2000;46(9):1301-9.
2000: Y M Dennis Lo; Sing-Fai Leung; Lisa Y S Chan; Anthony T C Chan; Kwok-Wai Lo; PJ Johnson; Dolly P Huang
Kinetics of plasma Epstein-Barr virus DNA during radiation therapy for nasopharyngeal carcinoma.
Cancer research 2000;60(9):2351-5.
2000: J Zhang; Carrie Fidler; M F Murphy; P F Chamberlain; I L Sargent; C W Redman; NM Hjelm; james wainscoat; Y M Dennis Lo
Determination of fetal RhD status by maternal plasma DNA analysis.
Annals of the New York Academy of Sciences 2000;906():153-5.
2000: Y M Dennis Lo
Fetal DNA in maternal plasma.
Annals of the New York Academy of Sciences 2000;906():141-7.
2000: IH Wong; Philip J Johnson; Paul B S Lai; WY Lau; Y M Dennis Lo
Tumor-derived epigenetic changes in the plasma and serum of liver cancer patients. Implications for cancer detection and monitoring.
Annals of the New York Academy of Sciences 2000;906():102-5.
2000: Y M Dennis Lo; S F Leung; Lisa Y S Chan; K W Lo; J Zhang; A T Chan; J C Lee; NM Hjelm; P J Johnson; D P Huang
Plasma cell-free Epstein-Barr virus DNA quantitation in patients with nasopharyngeal carcinoma. Correlation with clinical staging.
Annals of the New York Academy of Sciences 2000;906():99-101.
2000: Y M Dennis Lo; Timothy H Rainer; Lisa Y S Chan; N M Hjelm; Robert A Cocks
Plasma DNA as a prognostic marker in trauma patients.
Clinical chemistry 2000;46(3):319-23.
1999: Y M Dennis Lo; Lisa Y S Chan; Anthony T C Chan; Sing-Fai Leung; Kwok-Wai Lo; Jun Zhang; J C Lee; NM Hjelm; PJ Johnson; Dolly P Huang
Quantitative and temporal correlation between circulating cell-free Epstein-Barr virus DNA and tumor recurrence in nasopharyngeal carcinoma.
Cancer research 1999;59(21):5452-5.
1999: Nelson Tang; Tse N Leung; Jun Zhang; tze lau; Y M Dennis Lo
Detection of fetal-derived paternally inherited X-chromosome polymorphisms in maternal plasma.
Clinical chemistry 1999;45(11):2033-5.
1999: Y M Dennis Lo
Fetal RhD genotyping from maternal plasma.
Annals of medicine 1999;31(5):308-12.
1999: Y M Dennis Lo; tze lau; Jun Zhang; Tse N Leung; AM Chang; NM Hjelm; R S Elmes; Diana Bianchi
Increased fetal DNA concentrations in the plasma of pregnant women carrying fetuses with trisomy 21.
Clinical chemistry 1999;45(10):1747-51.
1999: Jun Zhang; KL Tong; P K Li; A Y Chan; Chung-Kwong Yeung; C C Pang; T Y Wong; K C Lee; Y M Dennis Lo
Presence of donor- and recipient-derived DNA in cell-free urine samples of renal transplantation recipients: urinary DNA chimerism.
Clinical chemistry 1999;45(10):1741-6.
1999: Y M Dennis Lo; Ivy H N Wong; Jun Zhang; MS Tein; M H Ng; NM Hjelm
Quantitative analysis of aberrant p16 methylation using real-time quantitative methylation-specific polymerase chain reaction.
Cancer research 1999;59(16):3899-903.
1999: Y M Dennis Lo; Lisa Y S Chan; Kwok-Wai Lo; Sing-Fai Leung; Jun Zhang; Anthony T C Chan; J C Lee; NM Hjelm; PJ Johnson; Dolly P Huang
Quantitative analysis of cell-free Epstein-Barr virus DNA in plasma of patients with nasopharyngeal carcinoma.
Cancer research 1999;59(6):1188-91.
1999: Y M Dennis Lo; Tse N Leung; MS Tein; I L Sargent; Jun Zhang; tze lau; C J Haines; C W Redman
Quantitative abnormalities of fetal DNA in maternal serum in preeclampsia.
Clinical chemistry 1999;45(2):184-8.
1999: Y M Dennis Lo; J Zhang; Tse N Leung; tze lau; AM Chang; NM Hjelm
Rapid clearance of fetal DNA from maternal plasma.
American journal of human genetics 1999;64(1):218-24.
1999: Ivy H N Wong; Y M Dennis Lo; Jun Zhang; C T Liew; M H Ng; N Wong; Paul B S Lai; W Y Lau; NM Hjelm; P J Johnson
Detection of aberrant p16 methylation in the plasma and serum of liver cancer patients.
Cancer research 1999;59(1):71-3.
1998: Tse N Leung; J Zhang; tze lau; NM Hjelm; Y M Dennis Lo
Maternal plasma fetal DNA as a marker for preterm labour.
Lancet 1998;352(9144):1904-5.
1998: Y M Dennis Lo; NM Hjelm; Carrie Fidler; I L Sargent; M F Murphy; P F Chamberlain; Priscilla M K Poon; C W Redman; james wainscoat
Prenatal diagnosis of fetal RhD status by molecular analysis of maternal plasma.
The New England journal of medicine 1998;339(24):1734-8.
1998: Y M Dennis Lo; MS Tein; C C Pang; Chung-Kwong Yeung; KL Tong; NM Hjelm
Presence of donor-specific DNA in plasma of kidney and liver-transplant recipients.
Lancet 1998;351(9112):1329-30.
1998: Y M Dennis Lo; MS Tein; tze lau; C J Haines; Tse N Leung; Priscilla M K Poon; james wainscoat; P J Johnson; AM Chang; NM Hjelm
Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive prenatal diagnosis.
American journal of human genetics 1998;62(4):768-75.
1998: E S Lo; Y M Dennis Lo; NM Hjelm; B Thilaganathan
Transfer of nucleated maternal cells into fetal circulation during the second trimester of pregnancy.
British journal of haematology 1998;100(3):605-6.
1997: Y M Dennis Lo; N Corbetta; Paul Chamberlain; VS Rai; I L Sargent; C W G Redman; james wainscoat
Presence of fetal DNA in maternal plasma and serum.
Lancet 1997;350(9076):485-7.
1996: Y M Dennis Lo; E S Lo; N Watson; L Noakes; Ian L Sargent; B Thilaganathan; james wainscoat
Two-way cell traffic between mother and fetus: biologic and clinical implications.
Blood 1996;88(11):4390-5.
1996: PJ Saker; Andrew T Hattersley; BA Barrow; MS Hammersley; J A McLellan; Y M Dennis Lo; R J Olds; M D Gillmer; Rury R Holman; RC Turner
High prevalence of a missense mutation of the glucokinase gene in gestational diabetic patients due to a founder-effect in a local population.
Diabetologia 1996;39(11):1325-8.
1996: Y M Dennis Lo
Noninvasive prenatal diagnosis using fetal cells in maternal blood.
Methods in molecular medicine 1996;5():237-44.
1995: W Waggott; Y M Dennis Lo; Christian Bastard; K C Gatter; Dominique Leroux; David Y Mason; Jacqueline Boultwood; james wainscoat
Detection of NPM-ALK DNA rearrangement in CD30 positive anaplastic large cell lymphoma.
British journal of haematology 1995;89(4):905-7.
1995: Y M Dennis Lo; L Noakes; E Roux; M Jeannet; B Chapuis; K A Fleming; james wainscoat
Application of a polymorphic Y microsatellite to the detection of post bone marrow transplantation chimaerism.
British journal of haematology 1995;89(3):645-9.
1995: Y M Dennis Lo; S Darby; L Noakes; E Whitley; P B Silcocks; K A Fleming; J I Bell
Screening for codon 249 p53 mutation in lung cancer associated with domestic radon exposure.
Lancet 1995;345(8941):60.
1995: Virginia Horton; M Bunce; D R Davies; RC Turner; Y M Dennis Lo
HLA typing for DR3 and DR4 using artificial restriction fragment length polymorphism PCR from archival DNA.
Journal of clinical pathology 1995;48(1):33-6.
1994: W Z Mehal; Y M Dennis Lo; C S Herrington; M F Evans; M C Papadopoulos; K Odunis; Trivadi Ganesan; James O'D McGee; John I Bell; K A Fleming
Role of human papillomavirus in determining the HLA associated risk of cervical carcinogenesis.
Journal of clinical pathology 1994;47(12):1077-81.
1994: Y M Dennis Lo
Non-invasive prenatal diagnosis using fetal cells in maternal blood.
Journal of clinical pathology 1994;47(12):1060-5.
1994: W Z Mehal; W L Gregory; Y M Dennis Lo; S J Cross; K A Fleming; Margaret F Bassendine; Oliver F W James; R Duncan Campbell; R W Chapman; W M Rosenberg
Defining the immunogenetic susceptibility to primary biliary cirrhosis.
Hepatology (Baltimore, Md.) 1994;20(5):1213-9.
1994: Y M Dennis Lo; P J Bowell; M Selinger; Ian Z Mackenzie; Paul Chamberlain; M D Gillmer; P Elliott; G Pratt; T J Littlewood; K A Fleming
Prenatal determination of fetal rhesus D status by DNA amplification of peripheral blood of rhesus-negative mothers.
Annals of the New York Academy of Sciences 1994;731():229-36.
1994: Y M Dennis Lo; J Schmidtke; james wainscoat; K A Fleming
An improved PCR-based system for prenatal sex determination from maternal peripheral blood.
Annals of the New York Academy of Sciences 1994;731():214-6.
1994: Y M Dennis Lo; K A Fleming; james wainscoat
Strategies for the detection of autosomal fetal DNA sequence from maternal peripheral blood.
Annals of the New York Academy of Sciences 1994;731():204-13.
1994: Y M Dennis Lo; L Noakes; P J Bowell; K A Fleming; james wainscoat
Detection of fetal RhD sequence from peripheral blood of sensitized RhD-negative pregnant women.
British journal of haematology 1994;87(3):658-60.
1994: W Z Mehal; Y M Dennis Lo; B Paul Wordsworth; J M Neuberger; S C Hubscher; K A Fleming; R W Chapman
HLA DR4 is a marker for rapid disease progression in primary sclerosing cholangitis.
Gastroenterology 1994;106(1):160-7.
1993: Y M Dennis Lo; E Roux; M Jeannet; B Chapuis; K A Fleming; james wainscoat
Detection of chimaerism after bone marrow transplantation using the double amplification refractory mutation system.
British journal of haematology 1993;85(1):223-6.
1993: W Z Mehal; Margaret M Esiri; Y M Dennis Lo; R W Chapman; K A Fleming
Detection of reactivation and size variation in the regulatory region of JC virus in brain tissue.
Journal of clinical pathology 1993;46(7):646-9.
1993: Y M Dennis Lo; P J Bowell; M Selinger; Ian Z Mackenzie; Paul Chamberlain; M D Gillmer; T J Littlewood; K A Fleming; james wainscoat
Prenatal determination of fetal RhD status by analysis of peripheral blood of rhesus negative mothers.
Lancet 1993;341(8853):1147-8.
1993: Y M Dennis Lo; E S Lo; W Z Mehal; M Sampietro; G Fiorelli; G Ronchi; C H Tse; K A Fleming
Geographical variation in prevalence of hepatitis B virus DNA in HBsAg negative patients.
Journal of clinical pathology 1993;46(4):304-8.
1993: Andrew T Hattersley; PJ Saker; P Patel; Y M Dennis Lo; R Page; Stephen O'Rahilly; RC Turner; M A Permutt; james wainscoat
Linkage of maturity-onset diabetes of the young to the glucokinase gene--evidence of genetic heterogeneity.
Biochemical Society transactions 1993;21(1):24S.
1993: Y M Dennis Lo; P Patel; C N Baigent; M D Gillmer; Paul Chamberlain; M Travi; Maurizio Sampietro; james wainscoat; K A Fleming
Prenatal sex determination from maternal peripheral blood using the polymerase chain reaction.
Human genetics 1993;90(5):483-8.
1992: M Stoffel; P Patel; Y M Dennis Lo; Andrew T Hattersley; A M Lucassen; R Page; J I Bell; Graeme I Bell; RC Turner; james wainscoat
Missense glucokinase mutation in maturity-onset diabetes of the young and mutation screening in late-onset diabetes.
Nature genetics 1992;2(2):153-6.
1992: E S Lo; Y M Dennis Lo; C H Tse; K A Fleming
Detection of hepatitis B pre-core mutant by allele specific polymerase chain reaction.
Journal of clinical pathology 1992;45(8):689-92.
1992: Y M Dennis Lo; P Patel; W Z Mehal; K A Fleming; John I Bell; james wainscoat
Analysis of complex genetic systems by ARMS-SSCP: application to HLA genotyping.
Nucleic acids research 1992;20(5):1005-9.
1992: A T Hattersley; Y M Dennis Lo; S J Read; R P Eglin; james wainscoat; A Clark
Failure to detect cytomegalovirus DNA in pancreas in type 2 diabetes.
Lancet 1992;339(8791):459-60.
1992: P Patel; Y M Dennis Lo; John I Bell; james wainscoat
Detection of susceptibility alleles to insulin-dependent diabetes mellitus at the DQB1 locus by artificial PCR-RFLP.
Immunogenetics 1992;36(4):264-5.
1991: Y M Dennis Lo; E S Lo; P Patel; C H Tse; K A Fleming
Heteroduplex formation as a means to exclude contamination in virus detection using PCR.
Nucleic acids research 1991;19(23):6653.
1991: P Patel; Y M Dennis Lo; G I Bell; RC Turner; james wainscoat
Dinucleotide repeat polymorphism at the human GLUT2 locus.
Nucleic acids research 1991;19(14):4017.
1991: Y M Dennis Lo; P Patel; C R Newton; A F Markham; K A Fleming; james wainscoat
Direct haplotype determination by double ARMS: specificity, sensitivity and genetic applications.
Nucleic acids research 1991;19(13):3561-7.
1991: Y M Dennis Lo; W Z Mehal; B P Wordsworth; R W Chapman; K A Fleming; John I Bell; james wainscoat
HLA typing by double ARMS.
Lancet 1991;338(8758):65-6.
1990: Y M Dennis Lo; P Patel; M Sampietro; M D Gillmer; K A Fleming; james wainscoat
Detection of single-copy fetal DNA sequence from maternal blood.
Lancet 1990;335(8703):1463-4.
1989: Y M Dennis Lo; P Patel; james wainscoat; M Sampietro; M D Gillmer; K A Fleming
Prenatal sex determination by DNA amplification from maternal peripheral blood.
Lancet 1989;2(8676):1363-5.
1989: Y M Dennis Lo; W Z Mehal; K A Fleming
In vitro amplification of hepatitis B virus sequences from liver tumour DNA and from paraffin wax embedded tissues using the polymerase chain reaction.
Journal of clinical pathology 1989;42(8):840-6.
1988: Y M Dennis Lo; W Z Mehal; K A Fleming
False-positive results and the polymerase chain reaction.
Lancet 1988;2(8612):679.
1988: Y M Dennis Lo; W Z Mehal; K A Fleming
Rapid production of vector-free biotinylated probes using the polymerase chain reaction.
Nucleic acids research 1988;16(17):8719.