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Joan Loader

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Shama Ahmad; Jorge Di Paola; Tara Hendry-Hofer; Joan E Loader; Keith B Neeves; Raymond C Rancourt; Susan D Reynolds; Aftab Ahmad; Carl W White
Tissue factor signals airway epithelial basal cell survival via coagulation and protease-activated receptor isoforms 1 and 2.
Judy L Oakes; Brian P O'Connor; David A Schwartz; Laura A Warg; Rachel Burton; Ashley Hock; Lucy Hui; Jian Jing; Daniel Laflamme; Joan E Loader; Ivana V Yang
Ozone enhances pulmonary innate immune response to a Toll-like receptor-2 agonist.
Heidi C O'Neill; David J Orlicky; Brian Day; Tara B Hendry-Hofer; Joan E Loader; Carl W White
Role of reactive oxygen and nitrogen species in olfactory epithelial injury by the sulfur mustard analogue 2-chloroethyl ethyl sulfide.

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All Publications

2013: Shama Ahmad; Jorge Di Paola; Tara Hendry-Hofer; Joan E Loader; Keith B Neeves; Raymond C Rancourt; Susan D Reynolds; Aftab Ahmad; Carl W White
Tissue factor signals airway epithelial basal cell survival via coagulation and protease-activated receptor isoforms 1 and 2.
American journal of respiratory cell and molecular biology 2013;48(1):94-104.
2013: Judy L Oakes; Brian P O'Connor; David A Schwartz; Laura A Warg; Rachel Burton; Ashley Hock; Lucy Hui; Jian Jing; Daniel Laflamme; Joan E Loader; Ivana V Yang
Ozone enhances pulmonary innate immune response to a Toll-like receptor-2 agonist.
American journal of respiratory cell and molecular biology 2013;48(1):27-34.
2011: Heidi C O'Neill; David J Orlicky; Brian Day; Tara B Hendry-Hofer; Joan E Loader; Carl W White
Role of reactive oxygen and nitrogen species in olfactory epithelial injury by the sulfur mustard analogue 2-chloroethyl ethyl sulfide.
American journal of respiratory cell and molecular biology 2011;45(2):323-31.
2010: Livia A Veress; Heidi C O'Neill; Tara B Hendry-Hofer; Joan E Loader; Raymond C Rancourt; Carl W White
Airway obstruction due to bronchial vascular injury after sulfur mustard analog inhalation.
American journal of respiratory and critical care medicine 2010;182(11):1352-61.
2010: Heidi C O'Neill; Carl W White; Livia A Veress; Tara B Hendry-Hofer; Joan E Loader; Elysia Min; Jie Huang; Raymond C Rancourt; Brian Day
Treatment with the catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of the sulfur mustard analog 2-chloroethyl ethyl sulfide.
Free radical biology & medicine 2010;48(9):1188-96.
2009: Shama Ahmad; Aftab Ahmad; Elena S Dremina; Victor S Sharov; Xiaoling Guo; Tara N Jones; Joan E Loader; Jason R Tatreau; Anne-Laure Perraud; Christian Schöneich; Scott H Randell; Carl W White
Bcl-2 suppresses sarcoplasmic/endoplasmic reticulum Ca2+-ATPase expression in cystic fibrosis airways: role in oxidant-mediated cell death.
American journal of respiratory and critical care medicine 2009;179(9):816-26.
2008: Shigeki Matsubara; Christina H Swasey; Joan E Loader; Azzeddine Dakhama; Anthony Joetham; Hiroshi Ohnishi; Annette Balhorn; Nobuaki Miyahara; Katsuyuki Takeda; Erwin W Gelfand
Estrogen determines sex differences in airway responsiveness after allergen exposure.
American journal of respiratory cell and molecular biology 2008;38(5):501-8.
2007: Gary L Larsen; Joan E Loader; Cori Fratelli; June-Ku Brian Kang; Azzeddine Dakhama; Giuseppe N Colasurdo
Modulation of airway responses by prostaglandins in young and fully grown rabbits.
American journal of physiology. Lung cellular and molecular physiology 2007;293(1):L239-44.
2007: Michelle A Carey; Jeffrey W Card; J Alyce Bradbury; Michael P Moorman; Najwa Haykal-Coates; Stephen H Gavett; Joan P Graves; Vickie R Walker; Gordon P Flake; James W Voltz; Daling Zhu; Elizabeth R Jacobs; Azzeddine Dakhama; Gary L Larsen; Joan E Loader; Erwin W Gelfand; Dori R Germolec; Kenneth S Korach; Darryl C Zeldin
Spontaneous airway hyperresponsiveness in estrogen receptor-alpha-deficient mice.
American journal of respiratory and critical care medicine 2007;175(2):126-35.
2006: Gary L Larsen; Cori Fratelli; Joan E Loader; June-Ku Brian Kang; Azzeddine Dakhama
Neuropeptide release from airways of young and fully-grown rabbits.
Pediatric pulmonology 2006;41(12):1242-9.
2006: Christian Taube; Nobuaki Miyahara; Vanessa L Ott; Brad Swanson; Katsuyuki Takeda; Joan E Loader; Leonard D Shultz; Andrew M Tager; Andrew D Luster; Azzeddine Dakhama; Erwin W Gelfand
The leukotriene B4 receptor (BLT1) is required for effector CD8+ T cell-mediated, mast cell-dependent airway hyperresponsiveness.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(5):3157-64.
2006: Gary L Larsen; Joan E Loader; Cori Fratelli; June-Ku Brian Kang; Azzeddine Dakhama; Giuseppe N Colasurdo
Phosphodiesterase IV and neutral endopeptidase in airways from developing and allergen sensitized rabbits.
Pulmonary pharmacology & therapeutics 2006;19(5):335-42.
2006: Shigeki Matsubara; Guiming Li; Katsuyuki Takeda; Joan E Loader; Polly Pine; Esteban S Masuda; Nobuaki Miyahara; Satoko Miyahara; Joseph J Lucas; Azzeddine Dakhama; Erwin W Gelfand
Inhibition of spleen tyrosine kinase prevents mast cell activation and airway hyperresponsiveness.
American journal of respiratory and critical care medicine 2006;173(1):56-63.
2005: Azzeddine Dakhama; Jung-Won Park; Christian Taube; Mohamed El Gazzar; Taku Kodama; Nobuaki Miyahara; Katsuyuki Takeda; Arihiko Kanehiro; Annette Balhorn; Anthony Joetham; Joan E Loader; Gary L Larsen; Erwin W Gelfand
Alteration of airway neuropeptide expression and development of airway hyperresponsiveness following respiratory syncytial virus infection.
American journal of physiology. Lung cellular and molecular physiology 2005;288(4):L761-70.
2004: Gary L Larsen; Joan E Loader; Dee Dee Nguyen; Cori Fratelli; Azzeddine Dakhama; Giuseppe N Colasurdo
Mechanisms determining cholinergic neural responses in airways of young and mature rabbits.
Pediatric pulmonology 2004;38(2):97-106.
2004: Christian Taube; Xudong Wei; Christina H Swasey; Anthony Joetham; Simona Zarini; Tricia Lively; Katsuyuki Takeda; Joan E Loader; Nobuaki Miyahara; Taku Kodama; Leonard D Shultz; Debra D Donaldson; Eckard H Hamelmann; Azzeddine Dakhama; Erwin W Gelfand
Mast cells, Fc epsilon RI, and IL-13 are required for development of airway hyperresponsiveness after aerosolized allergen exposure in the absence of adjuvant.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(10):6398-406.
2002: Azzeddine Dakhama; Arihiko Kanehiro; Mika J Mäkelä; Joan E Loader; Gary L Larsen; Erwin W Gelfand
Regulation of airway hyperresponsiveness by calcitonin gene-related peptide in allergen sensitized and challenged mice.
American journal of respiratory and critical care medicine 2002;165(8):1137-44.
2001: Gary L Larsen; Joan E Loader; Dee Dee Nguyen; Giuseppe N Colasurdo
Mechanisms of cholinergic dysfunction in rabbits following recurrent aspiration of cow's milk.
Pediatric pulmonology 2001;32(6):409-17.
2000: Gary L Larsen; Carl W White; Katsuyuki Takeda; Joan E Loader; Dee Dee Nguyen; Anthony Joetham; Y Groner; Erwin W Gelfand
Mice that overexpress Cu/Zn superoxide dismutase are resistant to allergen-induced changes in airway control.
American journal of physiology. Lung cellular and molecular physiology 2000;279(2):L350-9.
2000: Mika J Mäkelä; Arihiko Kanehiro; Larry Borish; Azzeddine Dakhama; Joan E Loader; Anthony Joetham; Zhou Xing; Manel Jordana; Gary L Larsen; Erwin W Gelfand
IL-10 is necessary for the expression of airway hyperresponsiveness but not pulmonary inflammation after allergic sensitization.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):6007-12.
2000: Angela Haczku; Katsuyuki Takeda; Eckard H Hamelmann; Joan E Loader; Anthony Joetham; I Redai; Charles G Irvin; James J Lee; H Kikutani; D Conrad; Erwin W Gelfand
CD23 exhibits negative regulatory effects on allergic sensitization and airway hyperresponsiveness.
American journal of respiratory and critical care medicine 2000;161(3 Pt 1):952-60.
1999: Angela Haczku; Katsuyuki Takeda; I Redai; Eckard H Hamelmann; Grzegorz Cieslewicz; Anthony Joetham; Joan E Loader; James J Lee; C Irvin; Erwin W Gelfand
Anti-CD86 (B7.2) treatment abolishes allergic airway hyperresponsiveness in mice.
American journal of respiratory and critical care medicine 1999;159(5 Pt 1):1638-43.
1998: Giuseppe N Colasurdo; Val G Hemming; Gregory A Prince; A S Gelfand; Joan E Loader; Gary L Larsen
Human respiratory syncytial virus produces prolonged alterations of neural control in airways of developing ferrets.
American journal of respiratory and critical care medicine 1998;157(5 Pt 1):1506-11.
1997: Angela Haczku; Katsuyuki Takeda; Eckard H Hamelmann; A Oshiba; Joan E Loader; Anthony Joetham; C Irvin; H Kikutani; Erwin W Gelfand
CD23 deficient mice develop allergic airway hyperresponsiveness following sensitization with ovalbumin.
American journal of respiratory and critical care medicine 1997;156(6):1945-55.
1997: Eckard H Hamelmann; A Oshiba; J Schwarze; K Bradley; Joan E Loader; Gary L Larsen; Erwin W Gelfand
Allergen-specific IgE and IL-5 are essential for the development of airway hyperresponsiveness.
American journal of respiratory cell and molecular biology 1997;16(6):674-82.
1997: Eckard H Hamelmann; A Oshiba; Joan E Loader; Gary L Larsen; G Gleich; J Lee; Erwin W Gelfand
Antiinterleukin-5 antibody prevents airway hyperresponsiveness in a murine model of airway sensitization.
American journal of respiratory and critical care medicine 1997;155(3):819-25.
1997: A S Gelfand; Gary L Larsen; Joan E Loader; Joan P Graves; Leland L Fan; Giuseppe N Colasurdo
Effect of aspiration of milk on mechanisms of neural control in the airways of developing rabbits.
Pediatric pulmonology 1997;23(3):198-204.
1996: G Lack; K L Bradley; Eckard H Hamelmann; H Renz; Joan E Loader; Donald Y M Leung; G Larsen; Erwin W Gelfand
Nebulized IFN-gamma inhibits the development of secondary allergic responses in mice.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(4):1432-9.
1996: Eckard H Hamelmann; A Oshiba; J Paluh; K Bradley; Joan E Loader; T A Potter; Gary L Larsen; Erwin W Gelfand
Requirement for CD8+ T cells in the development of airway hyperresponsiveness in a marine model of airway sensitization.
The Journal of experimental medicine 1996;183(4):1719-29.
1996: A Oshiba; Eckard H Hamelmann; K Takeda; K L Bradley; Joan E Loader; Gary L Larsen; Erwin W Gelfand
Passive transfer of immediate hypersensitivity and airway hyperresponsiveness by allergen-specific immunoglobulin (Ig) E and IgG1 in mice.
The Journal of clinical investigation 1996;97(6):1398-408.
1996: H Renz; K Bradley; K Enssle; Joan E Loader; Gary L Larsen; E W Gelfand
Prevention of the development of immediate hypersensitivity and airway hyperresponsiveness following in vivo treatment with soluble IL-4 receptor.
International archives of allergy and immunology 1996;109(2):167-76.
1996: A Oshiba; Eckard H Hamelmann; K L Bradley; Joan E Loader; H Renz; Gary L Larsen; Erwin W Gelfand
Pretreatment with allergen prevents immediate hypersensitivity and airway hyperresponsiveness.
American journal of respiratory and critical care medicine 1996;153(1):102-9.
1995: G Lack; A Oshiba; K L Bradley; Joan E Loader; D Amran; Gary L Larsen; Erwin W Gelfand
Transfer of immediate hypersensitivity and airway hyperresponsiveness by IgE-positive B cells.
American journal of respiratory and critical care medicine 1995;152(6 Pt 1):1765-73.
1995: Giuseppe N Colasurdo; Val G Hemming; G A Prince; Joan E Loader; J P Graves; Gary L Larsen
Human respiratory syncytial virus affects nonadrenergic noncholinergic inhibition in cotton rat airways.
The American journal of physiology 1995;268(6 Pt 1):L1006-11.
1995: Giuseppe N Colasurdo; Joan E Loader; J P Graves; Gary L Larsen
Modulation of acetylcholine release in rabbit airways in vitro.
The American journal of physiology 1995;268(3 Pt 1):L432-7.
1995: Giuseppe N Colasurdo; Joan E Loader; J P Graves; Gary L Larsen
Substance P-induced contraction of airway smooth muscle in young and adult rabbits. Effects of epithelium removal and neutral endopeptidase inhibition.
Chest 1995;107(3 Suppl):126S.
1995: Giuseppe N Colasurdo; Joan E Loader; J P Graves; Gary L Larsen
SP-induced contraction of airway smooth muscle in normal and allergen-sensitized rabbits: mechanism of action.
Journal of applied physiology (Bethesda, Md. : 1985) 1995;78(2):428-32.
1994: Giuseppe N Colasurdo; Joan E Loader; J P Graves; Gary L Larsen
Maturation of nonadrenergic noncholinergic inhibitory system in normal and allergen-sensitized rabbits.
The American journal of physiology 1994;267(6 Pt 1):L739-44.
1994: T M Fame; Giuseppe N Colasurdo; Joan E Loader; J P Graves; Gary L Larsen
Decrease in the airways' nonadrenergic noncholinergic inhibitory system in allergen sensitized rabbits.
Pediatric pulmonology 1994;17(5):296-303.
1994: G Lack; H Renz; J Saloga; K L Bradley; Joan E Loader; Donald Y M Leung; G Larsen; Erwin W Gelfand
Nebulized but not parenteral IFN-gamma decreases IgE production and normalizes airways function in a murine model of allergen sensitization.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(5):2546-54.
1994: Gary L Larsen; T M Fame; H Renz; Joan E Loader; J Graves; M Hill; Erwin W Gelfand
Increased acetylcholine release in tracheas from allergen-exposed IgE-immune mice.
The American journal of physiology 1994;266(3 Pt 1):L263-70.
1994: H Renz; G Lack; J Saloga; Reinhard Schwinzer; K Bradley; Joan E Loader; Abraham Kupfer; Gary L Larsen; Erwin W Gelfand
Inhibition of IgE production and normalization of airways responsiveness by sensitized CD8 T cells in a mouse model of allergen-induced sensitization.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(1):351-60.
1993: H Renz; J Saloga; K L Bradley; Joan E Loader; J L Greenstein; G Larsen; Erwin W Gelfand
Specific V beta T cell subsets mediate the immediate hypersensitivity response to ragweed allergen.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(4):1907-17.
1993: H Renz; K Bradley; J Saloga; Joan E Loader; Gary L Larsen; Erwin W Gelfand
T cells expressing specific V beta elements regulate immunoglobulin E production and airways responsiveness in vivo.
The Journal of experimental medicine 1993;177(4):1175-80.
1992: Gary L Larsen; H Renz; Joan E Loader; K L Bradley; Erwin W Gelfand
Airway response to electrical field stimulation in sensitized inbred mice. Passive transfer of increased responsiveness with peribronchial lymph nodes.
The Journal of clinical investigation 1992;89(3):747-52.