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Adrian Lobito

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Adrian A Lobito; Jan Paul Medema; Tanit L Gabriel; Fiona C Kimberley
Disease causing mutations in the TNF and TNFR superfamilies: Focus on molecular mechanisms driving disease.
Adrian A Lobito; Sree R Ramani; Irene Tom; J Fernando Bazan; Elizabeth Luis; Wayne J Fairbrother; Wenjun Ouyang; Lino C Gonzalez
Murine insulin growth factor-like (IGFL) and human IGFL1 proteins are induced in inflammatory skin conditions and bind to a novel tumor necrosis factor receptor family member, IGFLR1.
Anna Simon; Heiyoung Park; Ravikanth Maddipati; Adrian A Lobito; Ariel C Bulua; Adrianna J Jackson; Jae Jin Chae; Catherine Rachel Ettinger; Heleen D de Koning; Anthony C Cruz; Daniel Kastner; Hirsh Komarow; Richard Siegel
Concerted action of wild-type and mutant TNF receptors enhances inflammation in TNF receptor 1-associated periodic fever syndrome.

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All Publications

2011: Adrian A Lobito; Jan Paul Medema; Tanit L Gabriel; Fiona C Kimberley
Disease causing mutations in the TNF and TNFR superfamilies: Focus on molecular mechanisms driving disease.
Trends in molecular medicine 2011;17(9):494-505.
2011: Adrian A Lobito; Sree R Ramani; Irene Tom; J Fernando Bazan; Elizabeth Luis; Wayne J Fairbrother; Wenjun Ouyang; Lino C Gonzalez
Murine insulin growth factor-like (IGFL) and human IGFL1 proteins are induced in inflammatory skin conditions and bind to a novel tumor necrosis factor receptor family member, IGFLR1.
The Journal of biological chemistry 2011;286(21):18969-81.
2010: Anna Simon; Heiyoung Park; Ravikanth Maddipati; Adrian A Lobito; Ariel C Bulua; Adrianna J Jackson; Jae Jin Chae; Catherine Rachel Ettinger; Heleen D de Koning; Anthony C Cruz; Daniel Kastner; Hirsh Komarow; Richard Siegel
Concerted action of wild-type and mutant TNF receptors enhances inflammation in TNF receptor 1-associated periodic fever syndrome.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(21):9801-6.
2007: Lilit Garibyan; Adrian A Lobito; Richard Siegel; Matthew E Call; Kai W Wucherpfennig; Raif S Geha
Dominant-negative effect of the heterozygous C104R TACI mutation in common variable immunodeficiency (CVID).
The Journal of clinical investigation 2007;117(6):1550-7.
2007: Fiona C Kimberley; Adrian A Lobito; Richard Siegel; Gavin Screaton
Falling into TRAPS--receptor misfolding in the TNF receptor 1-associated periodic fever syndrome.
Arthritis research & therapy 2007;9(4):217.
2006: seth masters; Adrian A Lobito; Jaejin Chae; Daniel Kastner
Recent advances in the molecular pathogenesis of hereditary recurrent fevers.
Current opinion in allergy and clinical immunology 2006;6(6):428-33.
2006: Jagan R Muppidi; Adrian A Lobito; Madhu Ramaswamy; J K Yang; L Wang; H Wu; Richard Siegel
Homotypic FADD interactions through a conserved RXDLL motif are required for death receptor-induced apoptosis.
Cell death and differentiation 2006;13(10):1641-50.
2006: Adrian A Lobito; Fiona C Kimberley; Jagan R Muppidi; Hirsh D Komarow; Adrianna J Jackson; Keith M Hull; Daniel Kastner; Gavin Screaton; Richard Siegel
Abnormal disulfide-linked oligomerization results in ER retention and altered signaling by TNFR1 mutants in TNFR1-associated periodic fever syndrome (TRAPS).
Blood 2006;108(4):1320-7.
2004: Richard Siegel; Jagan R Muppidi; Malabika Sarker; Adrian A Lobito; Melinda Jen; David Martin; Stephen E Straus; Michael J Lenardo
SPOTS: signaling protein oligomeric transduction structures are early mediators of death receptor-induced apoptosis at the plasma membrane.
The Journal of cell biology 2004;167(4):735-44.
2004: Adrian A Lobito; Marcela F Lopes; Michael J Lenardo
Ectopic T cell receptor expression causes B cell immunodeficiency in transgenic mice.
European journal of immunology 2004;34(3):890-8.
2003: Alexei Miagkov; Adrian A Lobito; Bingzhi Yang; Marcela F Lopes; Robert N Adams; Gregory R Palardy; Michele M Johnson; HughI McFarland; Michael J Lenardo; Daniel B Drachman
Production and characterization of a T cell receptor transgenic mouse recognizing the immunodominant epitope of the Torpedo californica acetylcholine receptor.
Annals of the New York Academy of Sciences 2003;998():379-83.
2002: Adrian A Lobito; Bingzhi Yang; Marcela F Lopes; Alexei Miagkov; Robert N Adams; Gregory R Palardy; Michele M Johnson; Hugh McFarland; Michael Recher; Daniel B Drachman; Michael J Lenardo
T cell receptor transgenic mice recognizing the immunodominant epitope of the Torpedo californica acetylcholine receptor.
European journal of immunology 2002;32(7):2055-67.
2001: Hugh McFarland; Adrian A Lobito; Michele M Johnson; Gregory R Palardy; C S Yee; Elaine K Jordan; Joseph A Frank; Nancy Tresser; C P Genain; JP Mueller; LA Matis; Michael J Lenardo
Effective antigen-specific immunotherapy in the marmoset model of multiple sclerosis.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(3):2116-21.
2000: Juehu Wang; Adrian A Lobito; F Shen; Felicita Hornung; A Winoto; Michael J Lenardo
Inhibition of Fas-mediated apoptosis by the B cell antigen receptor through c-FLIP.
European journal of immunology 2000;30(1):155-63.
1999: Juehu Wang; Lixin Zheng; Adrian A Lobito; Francis Ka-Ming Chan; Janet Dale; M Sneller; X Yao; Jennifer M Puck; Stephen E Straus; Michael J Lenardo
Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II.
Cell 1999;98(1):47-58.
1999: Hugh McFarland; Adrian A Lobito; Michele M Johnson; J T Nyswaner; Joseph A Frank; Gregory R Palardy; Nancy Tresser; C P Genain; JP Mueller; LA Matis; Michael J Lenardo
Determinant spreading associated with demyelination in a nonhuman primate model of multiple sclerosis.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(4):2384-90.