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Camille Locht

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Françoise Vermeulen; Danièle Vermeylen; Virginie Verscheure; Eliane Damis; Violette Dirix; Camille Locht; Françoise Mascart
Persistence at one year of age of antigen-induced cellular immune responses in preterm infants vaccinated against whooping cough: comparison of three different vaccines and effect of a booster dose.
Hana Kammoun; Marina De Filette; Anne-Sophie Debrie; Walter Fiers; Nathalie Mielcarek; Dominique Raze; Xavier Roux; Xavier Saelens; Tine Ysenbaert; Camille Locht
Immunogenicity of Live Attenuated B. pertussis BPZE1 Producing the Universal Influenza Vaccine Candidate M2e.
Louise H Lefrancois; Camille Locht; Dominique Raze; Ana Paula Teixeira-Gomes; Christelle C Bodier; Thierry Cochard; Florence B Gilbert; Grégoire Harichaux; Valérie Labas; Sophie Lecher; Franck Biet
Purification of native HBHA from Mycobacterium avium subsp. paratuberculosis.

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All Publications

2013: Françoise Vermeulen; Danièle Vermeylen; Virginie Verscheure; Eliane Damis; Violette Dirix; Camille Locht; Françoise Mascart
Persistence at one year of age of antigen-induced cellular immune responses in preterm infants vaccinated against whooping cough: comparison of three different vaccines and effect of a booster dose.
Vaccine 2013;31(15):1981-6.
2013: Hana Kammoun; Marina De Filette; Anne-Sophie Debrie; Walter Fiers; Nathalie Mielcarek; Dominique Raze; Xavier Roux; Xavier Saelens; Tine Ysenbaert; Camille Locht
Immunogenicity of Live Attenuated B. pertussis BPZE1 Producing the Universal Influenza Vaccine Candidate M2e.
PloS one 2013;8(3):e59198.
2013: Louise H Lefrancois; Camille Locht; Dominique Raze; Ana Paula Teixeira-Gomes; Christelle C Bodier; Thierry Cochard; Florence B Gilbert; Grégoire Harichaux; Valérie Labas; Sophie Lecher; Franck Biet
Purification of native HBHA from Mycobacterium avium subsp. paratuberculosis.
BMC research notes 2013;6():55.
2012: Camille Locht; Nathalie Mielcarek
New pertussis vaccination approaches: en route to protect newborns?
FEMS immunology and medical microbiology 2012;66(2):121-33.
2012: Steven G Smith; Rose Blitz; Sophie Lecher; Camille Locht; Hazel M Dockrell
Broad heparin-binding haemagglutinin-specific cytokine and chemokine response in infants following Mycobacterium bovis BCG vaccination.
European journal of immunology 2012;42(9):2511-22.
2012: Hana Kammoun; Anne-Sophie Debrie; Pascal Feunou Feunou; Benoit Foligne; Nathalie Mielcarek; Dominique Raze; Camille Locht
Dual mechanism of protection by live attenuated Bordetella pertussis BPZE1 against Bordetella bronchiseptica in mice.
Vaccine 2012;30(40):5864-70.
2012: Marion Flipo; Candide Hounsou; Hee Kyoung Jeon; Nathalie Lecat-Guillet; Zoé Lens; Florence Leroux; Camille Locht; Vincent Villeret; Nicolas Willand; René Wintjens; Alexandre Wohlkönig; Alain Baulard; Priscille Brodin; Thierry Christophe; Matthieu Desroses; Benoit Déprez
Discovery of novel N-phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high-throughput screening and synthesis.
Journal of medicinal chemistry 2012;55(14):6391-402.
2012: Xavier Carette; Benoit Deprez; Bertrand Dirié; Patrick England; Frédéric Frénois; Sylviane Hoos; Nathalie Lecat-Guillet; Zoé Lens; Guy Lippens; Camille Locht; Sameh H Soror; Vincent Villeret; Nicolas Willand; Eve Willery; René Wintjens; Alexandre Wohlkönig; Nicolas Blondiaux; Alain Baulard
Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands.
Nucleic acids research 2012;40(7):3018-30.
2012: Véronique Corbière; Timothy Doherty; Sophie Lecher; Camille Locht; Gaelle Pottier; Kinda Schepers; Virginie Verscheure; Florence Bonkain; Françoise Mascart
Risk stratification of latent tuberculosis defined by combined interferon gamma release assays.
PloS one 2012;7(8):e43285.
2012: Violette Dirix; Tessa Goetghebuer; Camille Locht; Françoise Vermeulen; Virginie Verscheure; Iris De Schutter; Françoise Mascart
Both CD4⁺ and CD8⁺ lymphocytes participate in the IFN-γ response to filamentous hemagglutinin from Bordetella pertussis in infants, children, and adults.
Clinical & developmental immunology 2012;2012():795958.
2012: Pierre Lebrun; Guy Lippens; Dominique Raze; Dirk Schwarzer; Jean-Michel Wieruszeski; Fabrice Allain; Franck Biet; Mathieu Carpentier; Alexander Dose; Bernd Fritzinger; Camille Locht
Differential contribution of the repeats to heparin binding of HBHA, a major adhesin of Mycobacterium tuberculosis.
PloS one 2012;7(3):e32421.
2011: Camille Locht; Loic Coutte; Nathalie Mielcarek
The ins and outs of pertussis toxin.
The FEBS journal 2011;278(23):4668-82.
2011: Rui Li; Annabelle Lim; Camille Locht; Stephanie T L Ow; Meng-Chee Phoon; Vincent T K Chow; Sylvie Alonso
Development of live attenuated Bordetella pertussis strains expressing the universal influenza vaccine candidate M2e.
Vaccine 2011;29(33):5502-11.
2011: Anne-Sophie Delattre; Bernard Clantin; Guy Lippens; Camille Locht; Nathalie Saint; Vincent Villeret; Eve Willery; Françoise Jacob-Dubuisson
Substrate recognition by the POTRA domains of TpsB transporter FhaC.
Molecular microbiology 2011;81(1):99-112.
2011: Catherine Baud; Diane de Paepe; Hervé Drobecq; Martine Gilleron; Irina Gutsche; Marc Jamin; Camille Locht; Eve Willery; Françoise Jacob-Dubuisson
Membrane-associated DegP in Bordetella chaperones a repeat-rich secretory protein.
Molecular microbiology 2011;80(6):1625-36.
2011: Louise H Lefrançois; Céline Pujol; Christelle C Bodier; Ana Paula Teixeira-Gomez; Hervé Drobecq; Marie-Laure Rosso; Dominique Raze; André Alves Dias; Jean-Pierre Hugot; Ofelia Chacon; Raul G Barletta; Camille Locht; Maria Cristina Vidal Pessolani; Franck Biet
Characterization of the Mycobacterium avium subsp. paratuberculosis laminin-binding/histone-like protein (Lbp/Hlp) which reacts with sera from patients with Crohn's disease.
Microbes and infection / Institut Pasteur 2011;13(6):585-94.
2011: Giorgio Fedele; Manuela Bianco; Anne-Sophie Debrie; Camille Locht; Clara Maria Ausiello
Attenuated Bordetella pertussis vaccine candidate BPZE1 promotes human dendritic cell CCL21-induced migration and drives a Th1/Th17 response.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(9):5388-96.
2011: Marion Flipo; Hee Kyoung Jeon; Nathalie Lecat-Guillet; Zoé Lens; Florence Leroux; Camille Locht; Catherine Piveteau; Prakash Rucktooa; Vincent Villeret; Alain Baulard; Priscille Brodin; Xavier Carette; Thierry Christophe; Fatma Demirkaya; Benoit Déprez; Matthieu Desroses; Bertrand Dirié; Nicolas Willand
Ethionamide boosters: synthesis, biological activity, and structure-activity relationships of a series of 1,2,4-oxadiazole EthR inhibitors.
Journal of medicinal chemistry 2011;54(8):2994-3010.
2011: David Hot; Christine Hubans; Rudy Antoine; Anthony D'Hondt; Camille Locht; Stéphanie Slupek; Bérénice Wulbrecht; Yves LEMOINE
Detection of small RNAs in Bordetella pertussis and identification of a novel repeated genetic element.
BMC genomics 2011;12():207.
2011: Maranibia Cardoso Oelemann; Harrison M Gomes; Eve Willery; Lia Possuelo; Karla Valéria Batista Lima; Caroline Allix-Béguec; Camille Locht; Yves-Olivier L Goguet de la Salmonière; Maria Cristina Gutierrez; Philip N Suffys; Philip Supply
The forest behind the tree: phylogenetic exploration of a dominant Mycobacterium tuberculosis strain lineage from a high tuberculosis burden country.
PloS one 2011;6(3):e18256.
2010: Gaëlle Piret; Rémi Desmet; Eric Diesis; Hervé Drobecq; Jérome Segers; Carine Rouanet; Anne-Sophie Debrie; Rabah Boukherroub; Camille Locht; Oleg Melnyk
Chips from chips: application to the study of antibody responses to methylated proteins.
Journal of proteome research 2010;9(12):6467-78.
2010: Nicolas Willand; Matthieu Desroses; Patrick Toto; Bertrand Dirié; Zoé Lens; Vincent Villeret; Prakash Rucktooa; Camille Locht; Alain Baulard; Benoit Deprez
Exploring drug target flexibility using in situ click chemistry: application to a mycobacterial transcriptional regulator.
ACS chemical biology 2010;5(11):1007-13.
2010: Anne-Sophie Delattre; Bernard Clantin; Nathalie Saint; Camille Locht; Vincent Villeret; Françoise Jacob-Dubuisson
Functional importance of a conserved sequence motif in FhaC, a prototypic member of the TpsB/Omp85 superfamily.
The FEBS journal 2010;277(22):4755-65.
2010: Pascal Feunou Feunou; Hana Kammoun; Anne-Sophie Debrie; Nathalie Mielcarek; Camille Locht
Long-term immunity against pertussis induced by a single nasal administration of live attenuated B. pertussis BPZE1.
Vaccine 2010;28(43):7047-53.
2010: Julien Herrou; Coralie Bompard; René Wintjens; Elian Dupré; Eve Willery; Vincent Villeret; Camille Locht; Rudy Antoine; Françoise Jacob-Dubuisson
Periplasmic domain of the sensor-kinase BvgS reveals a new paradigm for the Venus flytrap mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(40):17351-5.
2010: Sammy Place; Virginie Verscheure; Nour de San; Jean-Michel Hougardy; Kinda Schepers; Violette Dirix; Anne Dediste; Olivier Michel; Annie Drowart; Sabine D Allard; Timothy Doherty; Sophie Lecher; Camille Locht; Françoise Mascart
Heparin-binding, hemagglutinin-specific IFN-gamma synthesis at the site of infection during active tuberculosis in humans.
American journal of respiratory and critical care medicine 2010;182(6):848-54.
2010: Rui Li; Annabelle Lim; Meng-Chee Phoon; Teluguakula Narasaraju; Jowin K W Ng; Wee Peng Poh; Meng-Kwoon Sim; Vincent T K Chow; Camille Locht; Sylvie Alonso
Attenuated Bordetella pertussis protects against highly pathogenic influenza A viruses by dampening the cytokine storm.
Journal of virology 2010;84(14):7105-13.
2010: Gloria G Guerrero; Ann-Sophie Debrie; Camille Locht
Boosting with mycobacterial heparin-binding haemagglutinin enhances protection of Mycobacterium bovis BCG-vaccinated newborn mice against M. tuberculosis.
Vaccine 2010;28(27):4340-7.
2010: Carine Rouanet; Camille Locht
Boosting BCG to protect against TB.
Expert review of respiratory medicine 2010;4(3):339-48.
2010: H Kavanagh; C Noone; E Cahill; K English; Camille Locht; Bernard P Mahon
Attenuated Bordetella pertussis vaccine strain BPZE1 modulates allergen-induced immunity and prevents allergic pulmonary pathology in a murine model.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2010;40(6):933-41.
2010: Sujatha Narayanan; Soumya Swaminathan; Philip Supply; Sivakumar Shanmugam; Gopalan Narendran; Lalitha Hari; Ranjani Ramachandran; Camille Locht; Mohideen Shaheed Jawahar; Paranji Raman Narayanan
Impact of HIV infection on the recurrence of tuberculosis in South India.
The Journal of infectious diseases 2010;201(5):691-703.
2010: Nathalie Mielcarek; Anne-Sophie Debrie; Severine Mahieux; Camille Locht
Dose response of attenuated Bordetella pertussis BPZE1-induced protection in mice.
Clinical and vaccine immunology : CVI 2010;17(3):317-24.
2010: Françoise Vermeulen; Virginie Verscheure; Eliane Damis; Danièle Vermeylen; Gaëlle Leloux; Violette Dirix; Camille Locht; Françoise Mascart
Cellular immune responses of preterm infants after vaccination with whole-cell or acellular pertussis vaccines.
Clinical and vaccine immunology : CVI 2010;17(2):258-62.
2010: Rémi Desmet; Eric Diesis; Hervé Drobecq; Carine Rouanet; Karim Chemlal; Anne-Sophie Debrie; Jean-Michel Hougardy; Françoise Mascart; Camille Locht; Oleg Melnyk
In situ chemical modification of peptide microarrays: application to the study of the antibody responses to methylated antigens.
Methods in molecular biology (Clifton, N.J.) 2010;669():135-45.
2010: Pascal Feunou Feunou; Julie Bertout; Camille Locht
T- and B-cell-mediated protection induced by novel, live attenuated pertussis vaccine in mice. Cross protection against parapertussis.
PloS one 2010;5(4):e10178.
2009: V Dirix; Virginie Verscheure; Tessa Goetghebuer; Marc Hainaut; Anne-Sophie Debrie; Camille Locht; Françoise Mascart
Monocyte-derived interleukin-10 depresses the Bordetella pertussis- specific gamma interferon response in vaccinated infants.
Clinical and vaccine immunology : CVI 2009;16(12):1816-21.
2009: Carine Rouanet; Anne-Sophie Debrie; Sophie Lecher; Camille Locht
Subcutaneous boosting with heparin binding haemagglutinin increases BCG-induced protection against tuberculosis.
Microbes and infection / Institut Pasteur 2009;11(13):995-1001.
2009: V Dirix; Virginie Verscheure; Tessa Goetghebuer; Marc Hainaut; Anne-Sophie Debrie; Camille Locht; Françoise Mascart
Cytokine and antibody profiles in 1-year-old children vaccinated with either acellular or whole-cell pertussis vaccine during infancy.
Vaccine 2009;27(43):6042-7.
2009: C Baud; Helene Hodak; E Willery; Hervé Drobecq; Camille Locht; M Jamin; Françoise Jacob-Dubuisson
Role of DegP for two-partner secretion in Bordetella.
Molecular microbiology 2009;74(2):315-29.
2009: Ciaran M Skerry; Joseph P Cassidy; Karen English; Pascal Feunou-Feunou; Camille Locht; Bernard P Mahon
A live attenuated Bordetella pertussis candidate vaccine does not cause disseminating infection in gamma interferon receptor knockout mice.
Clinical and vaccine immunology : CVI 2009;16(9):1344-51.
2009: Nicolas Willand; Bertrand Dirié; Xavier Carette; Pablo Bifani; Amit Singhal; Matthieu Desroses; Florence Leroux; Eve Willery; Vanessa Mathys; Rebecca Déprez-Poulain; Guy Delcroix; Frédéric Frénois; Marc Aumercier; Camille Locht; Vincent Villeret; Benoit Déprez; Alain R Baulard
Synthetic EthR inhibitors boost antituberculous activity of ethionamide.
Nature medicine 2009;15(5):537-44.
2009: Julien Herrou; Anne-Sophie Debrie; Eve Willery; Geneviève Renauld-Mongénie; Geneviève Renaud-Mongénie; Camille Locht; Frits Mooi; Françoise Jacob-Dubuisson; Rudy Antoine
Molecular evolution of the two-component system BvgAS involved in virulence regulation in Bordetella.
PloS one 2009;4(9):e6996.
2009: Melanie Lechner; Karin Schmitt; Susanne Bauer; David Hot; Christine Hubans; Erwan Levillain; Camille Locht; Yves LEMOINE; Roy Gross
Genomic island excisions in Bordetella petrii.
BMC microbiology 2009;9():141.
2008: Claire Verbelen; Vincent Dupres; Dominique Raze; Coralie Bompard; Camille Locht; Yves F Dufrêne
Interaction of the mycobacterial heparin-binding hemagglutinin with actin, as evidenced by single-molecule force spectroscopy.
Journal of bacteriology 2008;190(23):7614-20.
2008: Pascal Feunou Feunou; Jamila Ismaili; Anne-Sophie Debrie; Ludovic Huot; David Hot; Dominique Raze; Yves LEMOINE; Camille Locht
Genetic stability of the live attenuated Bordetella pertussis vaccine candidate BPZE1.
Vaccine 2008;26(45):5722-7.
2008: POULAIN-GODEFROY Odile; Catherine Vendeville; Camille Locht; Gilles Riveau
Bordetella pertussis filamentous hemagglutinin delivered by mucosal routes enhances immunoglobulin levels in serum and mucosal fluids.
FEMS immunology and medical microbiology 2008;54(1):129-36.
2008: Camille Locht
A common vaccination strategy to solve unsolved problems of tuberculosis and pertussis?
Microbes and infection / Institut Pasteur 2008;10(9):1051-6.
2008: Helene Hodak; Alexandre Wohlkönig; Caroline Smet-Nocca; Hervé Drobecq; Jean-Michel Wieruszeski; Magalie Sénéchal; Isabelle Landrieu; Camille Locht; Marc Jamin; Françoise Jacob-Dubuisson
The peptidyl-prolyl isomerase and chaperone Par27 of Bordetella pertussis as the prototype for a new group of parvulins.
Journal of molecular biology 2008;376(2):414-26.
2008: Thierry Wirth; Falk Hildebrand; Caroline Allix-Béguec; Florian Wölbeling; Tanja Kubica; Kristin Kremer; Dick Van Soolingen; Sabine Rüsch-Gerdes; Camille Locht; Sylvain Brisse; Axel Meyer; Philip Supply; Stefan Niemann
Origin, spread and demography of the Mycobacterium tuberculosis complex.
PLoS pathogens 2008;4(9):e1000160.
2008: Si Ying Ho; Shi Qian Chua; Damian Guang Wei Foo; Camille Locht; Vincent T K Chow; Chit Laa Poh; Sylvie Alonso
Highly attenuated Bordetella pertussis strain BPZE1 as a potential live vehicle for delivery of heterologous vaccine candidates.
Infection and immunity 2008;76(1):111-9.
2007: Claire Verbelen; Dominique Raze; Frédérique Dewitte; Camille Locht; Yves F Dufrêne
Single-molecule force spectroscopy of mycobacterial adhesin-adhesin interactions.
Journal of bacteriology 2007;189(24):8801-6.
2007: J Herrou; Coralie Bompard; Rudy Antoine; A Leroy; Prakash Rucktooa; David Hot; Isabelle Huvent; Camille Locht; Vincent Villeret; Françoise Jacob-Dubuisson
Structure-based mechanism of ligand binding for periplasmic solute-binding protein of the Bug family.
Journal of molecular biology 2007;373(4):954-64.
2007: Camille Locht; Carine Rouanet; Jean-Michel Hougardy; Françoise Mascart
How a different look at latency can help to develop novel diagnostics and vaccines against tuberculosis.
Expert opinion on biological therapy 2007;7(11):1665-77.
2007: Jean-Michel Hougardy; Virginie Verscheure; Camille Locht; Françoise Mascart
In vitro expansion of CD4+CD25highFOXP3+CD127low/- regulatory T cells from peripheral blood lymphocytes of healthy Mycobacterium tuberculosis-infected humans.
Microbes and infection / Institut Pasteur 2007;9(11):1325-32.
2007: Bernard Clantin; Anne-Sophie Delattre; Prakash Rucktooa; Nathalie Saint; Albano C Méli; Camille Locht; Françoise Jacob-Dubuisson; Vincent Villeret
Structure of the membrane protein FhaC: a member of the Omp85-TpsB transporter superfamily.
Science (New York, N.Y.) 2007;317(5840):957-61.
2007: Jean-Michel Hougardy; Sammy Place; Marc Hildebrand; Annie Drowart; Anne-Sophie Debrie; Camille Locht; Françoise Mascart
Regulatory T cells depress immune responses to protective antigens in active tuberculosis.
American journal of respiratory and critical care medicine 2007;176(4):409-16.
2007: Prakash Rucktooa; Rudy Antoine; Julien Herrou; Isabelle Huvent; Camille Locht; Françoise Jacob-Dubuisson; Vincent Villeret; Coralie Bompard
Crystal structures of two Bordetella pertussis periplasmic receptors contribute to defining a novel pyroglutamic acid binding DctP subfamily.
Journal of molecular biology 2007;370(1):93-106.
2007: vikas srivastava; Carine Rouanet; Ranjana Srivastava; Ramalingam Bethunaickan; Camille Locht; Brahm S Srivastava
Macrophage-specific Mycobacterium tuberculosis genes: identification by green fluorescent protein and kanamycin resistance selection.
Microbiology (Reading, England) 2007;153(Pt 3):659-66.
2007: Hélène HOST; Hervé Drobecq; Camille Locht; Franco D Menozzi
Enzymatic methylation of the Mycobacterium tuberculosis heparin-binding haemagglutinin.
FEMS microbiology letters 2007;268(2):144-50.
2007: Mara Cardoso Oelemann; Roland Diel; Vincent Vatin; Walter Haas; Sabine Rüsch-Gerdes; Camille Locht; Stefan Niemann; Philip Supply
Assessment of an optimized mycobacterial interspersed repetitive- unit-variable-number tandem-repeat typing system combined with spoligotyping for population-based molecular epidemiology studies of tuberculosis.
Journal of clinical microbiology 2007;45(3):691-7.
2007: Franck Biet; Maria Angela de Melo Marques; Maggy Grayon; Erika Kopp Xavier da Silveira; Patrick J Brennan; Hervé Drobecq; Dominique Raze; Maria Cristina Vidal Pessolani; Camille Locht; Franco D Menozzi
Mycobacterium smegmatis produces an HBHA homologue which is not involved in epithelial adherence.
Microbes and infection / Institut Pasteur 2007;9(2):175-82.
2007: Françoise Mascart; Marc Hainaut; Alexandra Peltier; Virginie Verscheure; Jack Levy; Camille Locht
Modulation of the infant immune responses by the first pertussis vaccine administrations.
Vaccine 2007;25(2):391-8.
2007: L Amniai; Franck Biet; Philippe Marquillies; Camille Locht; Joël PESTEL; André-Bernard Tonnel; Catherine Duez
IL-18 does not increase allergic airway disease in mice when produced by BCG.
Journal of biomedicine & biotechnology 2007;2007():67276.
2007: Jean-Michel Hougardy; Kinda Schepers; Sammy Place; Annie Drowart; Véronique Lechevin; Virginie Verscheure; Anne-Sophie Debrie; Timothy Doherty; Jean-Paul Van Vooren; Camille Locht; Françoise Mascart
Heparin-binding-hemagglutinin-induced IFN-gamma release as a diagnostic tool for latent tuberculosis.
PloS one 2007;2(10):e926.
2007: Ramalingam Bethunaickan; Alain Baulard; Camille Locht; Alamelu Raja
Antibody response in pulmonary tuberculosis against recombinant 27kDa (MPT51, Rv3803c) protein of Mycobacterium tuberculosis.
Scandinavian journal of infectious diseases 2007;39(10):867-74.
2006: Philip Supply; Caroline Allix-Béguec; Sarah Lesjean; Mara Cardoso-Oelemann; Sabine Rüsch-Gerdes; Eve Willery; Evgueni Savine; Petra E W De Haas; Henk van Deutekom; Solvig Roring; Pablo Bifani; Natalia Kurepina; Barry Kreiswirth; Christophe Sola; Nalin Rastogi; Vincent Vatin; M Cristina Gutierrez; Maryse Fauville; Stefan Niemann; Robin A Skuce; Kristin Kremer; Camille Locht; Dick Van Soolingen
Proposal for standardization of optimized mycobacterial interspersed repetitive unit-variable-number tandem repeat typing of Mycobacterium tuberculosis.
Journal of clinical microbiology 2006;44(12):4498-510.
2006: Isabelle Huvent; Hassan Belrhali; Rudy Antoine; Coralie Bompard; Camille Locht; Françoise Jacob-Dubuisson; Vincent Villeret
Structural analysis of Bordetella pertussis BugE solute receptor in a bound conformation.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 11):1375-81.
2006: Xavier Hanoulle; Jean-Michel Wieruszeski; Pierre Rousselot-Pailley; Isabelle Landrieu; Camille Locht; Guy Lippens; Alain Baulard
Selective intracellular accumulation of the major metabolite issued from the activation of the prodrug ethionamide in mycobacteria.
The Journal of antimicrobial chemotherapy 2006;58(4):768-72.
2006: M Cristina Gutierrez; Niyaz Ahmed; Eve Willery; Sujatha Narayanan; Seyed E Hasnain; Devendra S Chauhan; Vishwa M Katoch; Véronique Vincent; Camille Locht; Philip Supply
Predominance of ancestral lineages of Mycobacterium tuberculosis in India.
Emerging infectious diseases 2006;12(9):1367-74.
2006: Nathalie Mielcarek; Anne-Sophie Debrie; Dominique Raze; Julie Bertout; Carine Rouanet; Amena Ben Younes; Colette Creusy; Jacquelyn T Engle; William Goldman; Camille Locht
Live attenuated B. pertussis as a single-dose nasal vaccine against whooping cough.
PLoS pathogens 2006;2(7):e65.
2006: Valérie Caro; David Hot; Ghislaine Guigon; Christine Hubans; Mathilde Arrivé; Guillaume Soubigou; Geneviève Renauld-Mongénie; Rudy Antoine; Camille Locht; Yves LEMOINE; Nicole Guiso
Temporal analysis of French Bordetella pertussis isolates by comparative whole-genome hybridization.
Microbes and infection / Institut Pasteur 2006;8(8):2228-35.
2006: Helene Hodak; Bernard Clantin; Eve Willery; Vincent Villeret; Camille Locht; Françoise Jacob-Dubuisson
Secretion signal of the filamentous haemagglutinin, a model two-partner secretion substrate.
Molecular microbiology 2006;61(2):368-82.
2006: Dominique Raze; Alex Veithen; Hiroko Sato; Rudy Antoine; Franco D Menozzi; Camille Locht
Genetic exchange of the S2 and S3 subunits in pertussis toxin.
Molecular microbiology 2006;60(5):1241-50.
2006: Camille Locht; Jean-Michel Hougardy; Carine Rouanet; Sammy Place; Françoise Mascart
Heparin-binding hemagglutinin, from an extrapulmonary dissemination factor to a powerful diagnostic and protective antigen against tuberculosis.
Tuberculosis (Edinburgh, Scotland) 2006;86(3-4):303-9.
2006: Nathalie Mielcarek; Anne-Sophie Debrie; Dominique Raze; Julie Quatannens; Jacquelyn T Engle; William Goldman; Camille Locht
Attenuated Bordetella pertussis: new live vaccines for intranasal immunisation.
Vaccine 2006;24 Suppl 2():S2-54-5.
2006: Isabelle Huvent; Hassan Belrhali; Rudy Antoine; Coralie Bompard; Camille Locht; Françoise Jacob-Dubuisson; Vincent Villeret
Crystal structure of Bordetella pertussis BugD solute receptor unveils the basis of ligand binding in a new family of periplasmic binding proteins.
Journal of molecular biology 2006;356(4):1014-26.
2006: Albano C Méli; Helene Hodak; Bernard Clantin; Camille Locht; Gérard Molle; Françoise Jacob-Dubuisson; Nathalie Saint
Channel properties of TpsB transporter FhaC point to two functional domains with a C-terminal protein-conducting pore.
The Journal of biological chemistry 2006;281(1):158-66.
2006: Magdalena Kowalewicz-Kulbat; Joël PESTEL; Franck Biet; Camille Locht; André-Bernard Tonnel; Magdalena Druszczyńska; Wieslawa Rudnicka
Mycobacterium bovis BCG mycobacteria--new application.
Polish journal of microbiology / Polskie Towarzystwo Mikrobiologów = The Polish Society of Microbiologists 2006;55(1):13-7.
2006: Franco D Menozzi; Venkata M Reddy; Delphine Cayet; Dominique Raze; Anne-Sophie Debrie; Marie-Pierre Dehouck; Roméo Cecchelli; Camille Locht
Mycobacterium tuberculosis heparin-binding haemagglutinin adhesin (HBHA) triggers receptor-mediated transcytosis without altering the integrity of tight junctions.
Microbes and infection / Institut Pasteur 2006;8(1):1-9.
2005: Henk van Deutekom; Philip Supply; Petra E W De Haas; Eve Willery; Susan P Hoijng; Camille Locht; Roel A Coutinho; Dick Van Soolingen
Molecular typing of Mycobacterium tuberculosis by mycobacterial interspersed repetitive unit-variable-number tandem repeat analysis, a more accurate method for identifying epidemiological links between patients with tuberculosis.
Journal of clinical microbiology 2005;43(9):4473-9.
2005: Rudy Antoine; Isabelle Huvent; Karim Chemlal; Isabelle Deray; Dominique Raze; Camille Locht; Françoise Jacob-Dubuisson
The periplasmic binding protein of a tripartite tricarboxylate transporter is involved in signal transduction.
Journal of molecular biology 2005;351(4):799-809.
2005: Laurent Kremer; Chantal de Chastellier; Gary Dobson; Kevin J C Gibson; Pablo Bifani; Stéphanie Balor; Jean-Pierre Gorvel; Camille Locht; David E Minnikin; Gurdyal S Besra
Identification and structural characterization of an unusual mycobacterial monomeromycolyl-diacylglycerol.
Molecular microbiology 2005;57(4):1113-26.
2005: Franck Biet; Catherine Duez; Laurent Kremer; Philippe Marquillies; L Amniai; André-Bernard Tonnel; Camille Locht; Joël PESTEL
Recombinant Mycobacterium bovis BCG producing IL-18 reduces IL-5 production and bronchoalveolar eosinophilia induced by an allergic reaction.
Allergy 2005;60(8):1065-72.
2005: Stéphane Temmerman; Sammy Place; Anne-Sophie Debrie; Camille Locht; Françoise Mascart
Effector functions of heparin-binding hemagglutinin-specific CD8+ T lymphocytes in latent human tuberculosis.
The Journal of infectious diseases 2005;192(2):226-32.
2005: Vincent Dupres; Franco D Menozzi; Camille Locht; Brian H Clare; Nicholas L Abbott; Stéphane Cuenot; Coralie Bompard; Dominique Raze; Yves F Dufrêne
Nanoscale mapping and functional analysis of individual adhesins on living bacteria.
Nature methods 2005;2(7):515-20.
2005: Sylvie Alonso; Eve Willery; Geneviève Renauld-Mongénie; Camille Locht
Production of nontypeable Haemophilus influenzae HtrA by recombinant Bordetella pertussis with the use of filamentous hemagglutinin as a carrier.
Infection and immunity 2005;73(7):4295-301.
2005: Anthony Ablordey; Jean Swings; Christine Hubans; Karim Chemlal; Camille Locht; Françoise Portaels; Philip Supply
Multilocus variable-number tandem repeat typing of Mycobacterium ulcerans.
Journal of clinical microbiology 2005;43(4):1546-51.
2005: Priska Peirs; Philippe Lefèvre; Samira Boarbi; Xiao-Ming Wang; Olivier Denis; Martine Braibant; Kevin Pethe; Camille Locht; Kris Huygen; Jean Content
Mycobacterium tuberculosis with disruption in genes encoding the phosphate binding proteins PstS1 and PstS2 is deficient in phosphate uptake and demonstrates reduced in vivo virulence.
Infection and immunity 2005;73(3):1898-902.
2005: Laurence Hibrand-Saint Oyant; Dorothée Bourges; Claire Chevaleyre; Dominique Raze; Camille Locht; henri salmon
Role of Bordetella bronchiseptica adenylate cyclase in nasal colonization and in development of local and systemic immune responses in piglets.
Veterinary research 2005;36(1):63-77.
2004: Isdore Chola Shamputa; Leen Rigouts; Lovet Achale Eyongeta; Nabil El Aila; Armand Van Deun; Abdul Hamid Salim; Eve Willery; Camille Locht; Philip Supply; Françoise Portaels
Genotypic and phenotypic heterogeneity among Mycobacterium tuberculosis isolates from pulmonary tuberculosis patients.
Journal of clinical microbiology 2004;42(12):5528-36.
2004: Marcela Parra; Thames Pickett; Giovanni Delogu; Veerabadran Dheenadhayalan; Anne-Sophie Debrie; Camille Locht; Michael J Brennan
The mycobacterial heparin-binding hemagglutinin is a protective antigen in the mouse aerosol challenge model of tuberculosis.
Infection and immunity 2004;72(12):6799-805.
2004: Frédéric Frénois; Jean Engohang-Ndong; Camille Locht; Alain Baulard; Vincent Villeret
Structure of EthR in a ligand bound conformation reveals therapeutic perspectives against tuberculosis.
Molecular cell 2004;16(2):301-7.
2004: Stéphane Temmerman; Kevin Pethe; Marcela Parra; Sylvie Alonso; Carine Rouanet; Thames Pickett; Annie Drowart; Anne-Sophie Debrie; Giovanni Delogu; Franco D Menozzi; Christian Sergheraert; Michael J Brennan; Françoise Mascart; Camille Locht
Methylation-dependent T cell immunity to Mycobacterium tuberculosis heparin-binding hemagglutinin.
Nature medicine 2004;10(9):935-41.
2004: Ramalingam Bethunaickan; Alain Baulard; Camille Locht; Paranji R Narayanan; Alamelu Raja
Cloning, expression, and purification of the 27 kDa (MPT51, Rv3803c) protein of Mycobacterium tuberculosis.
Protein expression and purification 2004;36(1):53-60.
2004: Yong-Jiang Sun; Richard Bellamy; Ann S G Lee; Sze Ta Ng; Sindhu Ravindran; Sin Yew Wong; Camille Locht; Philip Supply; Nicholas Paton
Use of mycobacterial interspersed repetitive unit-variable-number tandem repeat typing to examine genetic diversity of Mycobacterium tuberculosis in Singapore.
Journal of clinical microbiology 2004;42(5):1986-93.
2004: Bernard Clantin; Helene Hodak; Eve Willery; Camille Locht; Françoise Jacob-Dubuisson; Vincent Villeret
The crystal structure of filamentous hemagglutinin secretion domain and its implications for the two-partner secretion pathway.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(16):6194-9.
2004: Camille Locht; Rudy Antoine; Dominique Raze; Nathalie Mielcarek; David Hot; Yves LEMOINE; Françoise Mascart
Bordetella pertussis from functional genomics to intranasal vaccination.
International journal of medical microbiology : IJMM 2004;293(7-8):583-8.
2004: Nina Chevalier; Michael Moser; Hans-Georg Koch; Karl-Ludwig Schimz; Eve Willery; Camille Locht; Françoise Jacob-Dubuisson; Matthias Müller
Membrane targeting of a bacterial virulence factor harbouring an extended signal peptide.
Journal of molecular microbiology and biotechnology 2004;8(1):7-18.
2004: Loubna Tazi; Jamila El Baghdadi; Sarah Lesjean; Camille Locht; Philip Supply; Michel Tibayrenc; Anne-Laure Bañuls
Genetic diversity and population structure of Mycobacterium tuberculosis in Casablanca, a Moroccan city with high incidence of tuberculosis.
Journal of clinical microbiology 2004;42(1):461-6.
2004: Fanny Ewann; Camille Locht; Philip Supply
Intracellular autoregulation of the Mycobacterium tuberculosis PrrA response regulator.
Microbiology (Reading, England) 2004;150(Pt 1):241-6.
2004: Jean Engohang-Ndong; David Baillat; Marc Aumercier; Flore Bellefontaine; Gurdyal S Besra; Camille Locht; Alain Baulard
EthR, a repressor of the TetR/CamR family implicated in ethionamide resistance in mycobacteria, octamerizes cooperatively on its operator.
Molecular microbiology 2004;51(1):175-88.
2003: POULAIN-GODEFROY Odile; F D Menozzi; S Alonso; Catherine Vendeville; André Capron; Camille Locht; Gilles Riveau
Adjuvant activity of free Bordetella pertussis filamentous haemagglutinin delivered by mucosal routes.
Scandinavian journal of immunology 2003;58(5):503-10.
2003: Slavka Listvanova; Stéphane Temmerman; Patrick Stordeur; Virginie Verscheure; Sammy Place; Lin Zhou; Camille Locht; Françoise Mascart
Optimal kinetics for quantification of antigen-induced cytokines in human peripheral blood mononuclear cells by real-time PCR and by ELISA.
Journal of immunological methods 2003;281(1-2):27-35.
2003: Yann Guérardel; Emmanuel Maes; Volker Briken; Frédéric Chirat; Yves Leroy; Camille Locht; Gérard Strecker; Laurent Kremer
Lipomannan and lipoarabinomannan from a clinical isolate of Mycobacterium kansasii: novel structural features and apoptosis-inducing properties.
The Journal of biological chemistry 2003;278(38):36637-51.
2003: Loic Coutte; Eve Willery; Rudy Antoine; Hervé Drobecq; Camille Locht; Françoise Jacob-Dubuisson
Surface anchoring of bacterial subtilisin important for maturation function.
Molecular microbiology 2003;49(2):529-39.
2003: Christophe Sola; Ingrid Filliol; Eric Legrand; Sarah Lesjean; Camille Locht; Philip Supply; Nalin Rastogi
Genotyping of the Mycobacterium tuberculosis complex using MIRUs: association with VNTR and spoligotyping for molecular epidemiology and evolutionary genetics.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2003;3(2):125-33.
2003: David Hot; Rudy Antoine; Geneviève Renauld-Mongénie; Valérie Caro; B Hennuy; E Levillain; Ludovic Huot; G Wittmann; David Poncet; Françoise Jacob-Dubuisson; C Guyard; F Rimlinger; Luc Aujame; Edmond Godfroid; Nicole Guiso; Marie-José Quentin-Millet; Yves LEMOINE; Camille Locht
Differential modulation of Bordetella pertussis virulence genes as evidenced by DNA microarray analysis.
Molecular genetics and genomics : MGG 2003;269(4):475-86.
2003: Laurent Kremer; Lynn Dover; HECTOR MORBIDONI; Catherine Vilchèze; William N Maughan; Alain Baulard; Shiao-Chun Tu; Nadine Honoré; Vojo Deretic; James C Sacchettini; Camille Locht; William R. Jacobs Jr.; Gurdyal S Besra
Inhibition of InhA activity, but not KasA activity, induces formation of a KasA-containing complex in mycobacteria.
The Journal of biological chemistry 2003;278(23):20547-54.
2003: Maria Cristina Vidal Pessolani; Maria Angela M Marques; Venkata M Reddy; Camille Locht; Franco D Menozzi
Systemic dissemination in tuberculosis and leprosy: do mycobacterial adhesins play a role?
Microbes and infection / Institut Pasteur 2003;5(7):677-84.
2003: Franck Biet; Laurent Kremer; Isabelle Wolowczuk; Myriam Delacre; Camille Locht
Immune response induced by recombinant Mycobacterium bovis BCG producing the cholera toxin B subunit.
Infection and immunity 2003;71(5):2933-7.
2003: Loic Coutte; Sylvie Alonso; Nathalie Reveneau; Eve Willery; Brigitte Quatannens; Camille Locht; Françoise Jacob-Dubuisson
Role of adhesin release for mucosal colonization by a bacterial pathogen.
The Journal of experimental medicine 2003;197(6):735-42.
2003: Rudy Antoine; Françoise Jacob-Dubuisson; Hervé Drobecq; Eve Willery; Sarah Lesjean; Camille Locht
Overrepresentation of a gene family encoding extracytoplasmic solute receptors in Bordetella.
Journal of bacteriology 2003;185(4):1470-4.
2003: Françoise Mascart; Virginie Verscheure; Anne Malfroot; Marc Hainaut; Denis Piérard; Stéphane Temerman; Alexandra Peltier; Anne-Sophie Debrie; Jack Levy; Giuseppe Del Giudice; Camille Locht
Bordetella pertussis infection in 2-month-old infants promotes type 1 T cell responses.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(3):1504-9.
2003: Alain Baulard; Sudagar S Gurcha; Jean Engohang-Ndong; Kamila Gouffi; Camille Locht; Gurdyal S Besra
In vivo interaction between the polyprenol phosphate mannose synthase Ppm1 and the integral membrane protein Ppm2 from Mycobacterium smegmatis revealed by a bacterial two-hybrid system.
The Journal of biological chemistry 2003;278(4):2242-8.
2003: Philip Supply; Robin M Warren; Anne-Laure Bañuls; Sarah Lesjean; Gian D van der Spuy; Lee-Anne Lewis; Michel Tibayrenc; Paul D Van Helden; Camille Locht
Linkage disequilibrium between minisatellite loci supports clonal evolution of Mycobacterium tuberculosis in a high tuberculosis incidence area.
Molecular microbiology 2003;47(2):529-38.
2002: Evgueni Savine; Robin M Warren; Gian D van der Spuy; Nulda Beyers; Paul D van Helden; Camille Locht; Philip Supply
Stability of variable-number tandem repeats of mycobacterial interspersed repetitive units from 12 loci in serial isolates of Mycobacterium tuberculosis.
Journal of clinical microbiology 2002;40(12):4561-6.
2002: Franck Biet; Laurent Kremer; Isabelle Wolowczuk; Myriam Delacre; Camille Locht
Mycobacterium bovis BCG producing interleukin-18 increases antigen-specific gamma interferon production in mice.
Infection and immunity 2002;70(12):6549-57.
2002: Laurent Kremer; Yann Guérardel; Sudagar S Gurcha; Camille Locht; Gurdyal S Besra
Temperature-induced changes in the cell-wall components of Mycobacterium thermoresistibile.
Microbiology (Reading, England) 2002;148(Pt 10):3145-54.
2002: Yann Guerardel; Emmanuel Maes; Elisabeth Elass; Yves Leroy; Philippe Timmerman; Gurdyal S Besra; Camille Locht; Gérard Strecker; Laurent Kremer
Structural study of lipomannan and lipoarabinomannan from Mycobacterium chelonae. Presence of unusual components with alpha 1,3-mannopyranose side chains.
The Journal of biological chemistry 2002;277(34):30635-48.
2002: Kevin Pethe; Pablo Bifani; Hervé Drobecq; Christian Sergheraert; Anne-Sophie Debrie; Camille Locht; Franco D Menozzi
Mycobacterial heparin-binding hemagglutinin and laminin-binding protein share antigenic methyllysines that confer resistance to proteolysis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10759-64.
2002: Sylvie Alonso; Nathalie Reveneau; Kevin Pethe; Camille Locht
Eighty-kilodalton N-terminal moiety of Bordetella pertussis filamentous hemagglutinin: adherence, immunogenicity, and protective role.
Infection and immunity 2002;70(8):4142-7.
2002: Sudagar S Gurcha; Alain Baulard; Laurent Kremer; Camille Locht; D Branch Moody; Walter Muhlecker; Catherine E Costello; Dean Crick; Patrick J Brennan; Gurdyal S Besra
Ppm1, a novel polyprenol monophosphomannose synthase from Mycobacterium tuberculosis.
The Biochemical journal 2002;365(Pt 2):441-50.
2002: Caroline Roduit; Paola Bozzotti; Nathalie Mielcarek; Paul-Henri Lambert; Giuseppe del Giudice; Camille Locht; Claire-Anne Siegrist
Immunogenicity and protective efficacy of neonatal vaccination against Bordetella pertussis in a murine model: evidence for early control of pertussis.
Infection and immunity 2002;70(7):3521-8.
2002: Laurent Kremer; Lynn Dover; Séverine Carrère; K Madhavan Nampoothiri; Sarah Lesjean; Alistair K Brown; Patrick J Brennan; David E Minnikin; Camille Locht; Gurdyal S Besra
Mycolic acid biosynthesis and enzymic characterization of the beta-ketoacyl-ACP synthase A-condensing enzyme from Mycobacterium tuberculosis.
The Biochemical journal 2002;364(Pt 2):423-30.
2002: Fanny Ewann; Mary Jackson; Kevin Pethe; Andrea Cooper; Nathalie Mielcarek; Danielle Ensergueix; Brigitte Gicquel; Camille Locht; Philip Supply
Transient requirement of the PrrA-PrrB two-component system for early intracellular multiplication of Mycobacterium tuberculosis.
Infection and immunity 2002;70(5):2256-63.
2002: Franco D Menozzi; Anne-Sophie Debrie; Jean-Pierre Tissier; Camille Locht; Kevin Pethe; Dominique Raze
Interaction of human Tamm-Horsfall glycoprotein with Bordetella pertussis toxin.
Microbiology (Reading, England) 2002;148(Pt 4):1193-201.
2002: Nathalie Reveneau; Marie Claude Geoffroy; Camille Locht; Patrice Chagnaud; Annick Mercenier
Comparison of the immune responses induced by local immunizations with recombinant Lactobacillus plantarum producing tetanus toxin fragment C in different cellular locations.
Vaccine 2002;20(13-14):1769-77.
2002: Franco D Menozzi; Kevin Pethe; Pablo Bifani; Fabrice SONCIN; Michael J Brennan; Camille Locht
Enhanced bacterial virulence through exploitation of host glycosaminoglycans.
Molecular microbiology 2002;43(6):1379-86.
2002: Franck Biet; Camille Locht; Laurent Kremer
Immunoregulatory functions of interleukin 18 and its role in defense against bacterial pathogens.
Journal of molecular medicine (Berlin, Germany) 2002;80(3):147-62.
2002: Chantal Masungi; Stéphane Temmerman; Jean-Paul Van Vooren; Annie Drowart; Kevin Pethe; Franco D Menozzi; Camille Locht; Françoise Mascart
Differential T and B cell responses against Mycobacterium tuberculosis heparin-binding hemagglutinin adhesin in infected healthy individuals and patients with tuberculosis.
The Journal of infectious diseases 2002;185(4):513-20.
2001: Nathalie Reveneau; Sylvie Alonso; Françoise Jacob-Dubuisson; Annick Mercenier; Camille Locht
Tetanus toxin fragment C-specific priming by intranasal infection with recombinant Bordetella pertussis.
Vaccine 2001;20(5-6):926-33.
2001: Andrey V Kajava; Naiqian Cheng; R Cleaver; Martin Kessel; Martha N Simon; Eve Willery; Françoise Jacob-Dubuisson; Camille Locht; Alasdair C Steven
Beta-helix model for the filamentous haemagglutinin adhesin of Bordetella pertussis and related bacterial secretory proteins.
Molecular microbiology 2001;42(2):279-92.
2001: Philip Supply; Sarah Lesjean; Evgueni Savine; Kristin Kremer; Dick Van Soolingen; Camille Locht
Automated high-throughput genotyping for study of global epidemiology of Mycobacterium tuberculosis based on mycobacterial interspersed repetitive units.
Journal of clinical microbiology 2001;39(10):3563-71.
2001: Sylvie Alonso; Kevin Pethe; Nathalie Mielcarek; Dominique Raze; Camille Locht
Role of ADP-ribosyltransferase activity of pertussis toxin in toxin-adhesin redundancy with filamentous hemagglutinin during Bordetella pertussis infection.
Infection and immunity 2001;69(10):6038-43.
2001: Loic Coutte; Rudy Antoine; Hervé Drobecq; Camille Locht; Françoise Jacob-Dubuisson
Subtilisin-like autotransporter serves as maturation protease in a bacterial secretion pathway.
The EMBO journal 2001;20(18):5040-8.
2001: Isabelle Coppens; Sylvie Alonso; Rudy Antoine; Françoise Jacob-Dubuisson; Geneviève Renauld-Mongénie; E Jacobs; Camille Locht
Production of Neisseria meningitidis transferrin-binding protein B by recombinant Bordetella pertussis.
Infection and immunity 2001;69(9):5440-6.
2001: Laurent Kremer; K Madhavan Nampoothiri; Sarah Lesjean; Lynn Dover; S Graham; J Betts; Patrick J Brennan; David E Minnikin; Camille Locht; Gurdyal S Besra
Biochemical characterization of acyl carrier protein (AcpM) and malonyl-CoA:AcpM transacylase (mtFabD), two major components of Mycobacterium tuberculosis fatty acid synthase II.
The Journal of biological chemistry 2001;276(30):27967-74.
2001: Kevin Pethe; Sylvie Alonso; Franck Biet; Giovanni Delogu; Michael J Brennan; Camille Locht; Franco D Menozzi
The heparin-binding haemagglutinin of M. tuberculosis is required for extrapulmonary dissemination.
Nature 2001;412(6843):190-4.
2001: Camille Locht
[Cellular and acellular anti-pertussis vaccines].
Annales pharmaceutiques françaises 2001;59(3):198-205.
2001: E Pradel; Camille Locht
Expression of the putative siderophore receptor gene bfrZ is controlled by the extracytoplasmic-function sigma factor BupI in Bordetella bronchiseptica.
Journal of bacteriology 2001;183(9):2910-7.
2001: Françoise Jacob-Dubuisson; Camille Locht; Rudy Antoine
Two-partner secretion in Gram-negative bacteria: a thrifty, specific pathway for large virulence proteins.
Molecular microbiology 2001;40(2):306-13.
2001: A Fauconnier; Alex Veithen; P Gueirard; Rudy Antoine; L Wacheul; Camille Locht; A Bollen; Edmond Godfroid
Characterization of the type III secretion locus of Bordetella pertussis.
International journal of medical microbiology : IJMM 2001;290(8):693-705.
2001: E Mazars; Sarah Lesjean; AL Banuls; M Gilbert; V Vincent; Brigitte Gicquel; Michel Tibayrenc; Camille Locht; Philip Supply
High-resolution minisatellite-based typing as a portable approach to global analysis of Mycobacterium tuberculosis molecular epidemiology.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1901-6.
2001: Camille Locht; Rudy Antoine; Françoise Jacob-Dubuisson
Bordetella pertussis, molecular pathogenesis under multiple aspects.
Current opinion in microbiology 2001;4(1):82-9.
2001: L Dupré; Laurent Kremer; Isabelle Wolowczuk; Gilles Riveau; André Capron; Camille Locht
Immunostimulatory effect of IL-18-encoding plasmid in DNA vaccination against murine Schistosoma mansoni infection.
Vaccine 2001;19(11-12):1373-80.
2001: Kevin Pethe; Virginie Puech; Mamadou Daffé; C Josenhans; Hervé Drobecq; Camille Locht; Franco D Menozzi
Mycobacterium smegmatis laminin-binding glycoprotein shares epitopes with Mycobacterium tuberculosis heparin-binding haemagglutinin.
Molecular microbiology 2001;39(1):89-99.
2000: S Himpens; Camille Locht; P Supply
Molecular characterization of the mycobacterial SenX3-RegX3 two-component system: evidence for autoregulation.
Microbiology (Reading, England) 2000;146 Pt 12():3091-8.
2000: Alex Veithen; Dominique Raze; Camille Locht
Intracellular trafficking and membrane translocation of pertussis toxin into host cells.
International journal of medical microbiology : IJMM 2000;290(4-5):409-13.
2000: Rudy Antoine; Dominique Raze; Camille Locht
Genomics of Bordetella pertussis toxins.
International journal of medical microbiology : IJMM 2000;290(4-5):301-5.
2000: Rudy Antoine; Sylvie Alonso; Dominique Raze; Loic Coutte; Sarah Lesjean; Eve Willery; Camille Locht; Françoise Jacob-Dubuisson
New virulence-activated and virulence-repressed genes identified by systematic gene inactivation and generation of transcriptional fusions in Bordetella pertussis.
Journal of bacteriology 2000;182(20):5902-5.
2000: S Guédin; Eve Willery; J Tommassen; E Fort; Hervé Drobecq; Camille Locht; Françoise Jacob-Dubuisson
Novel topological features of FhaC, the outer membrane transporter involved in the secretion of the Bordetella pertussis filamentous hemagglutinin.
The Journal of biological chemistry 2000;275(39):30202-10.
2000: Alain Baulard; J C Betts; Jean Engohang-Ndong; S Quan; Ruth A McAdam; Patrick J Brennan; Camille Locht; Gurdyal S Besra
Activation of the pro-drug ethionamide is regulated in mycobacteria.
The Journal of biological chemistry 2000;275(36):28326-31.
2000: O Billaut-Mulot; T Idziorek; Elisabeth Ban; Laurent Kremer; L Dupré; M Loyens; Gilles Riveau; Camille Locht; André Capron; George M Bahr
Interleukin-18 modulates immune responses induced by HIV-1 Nef DNA prime/protein boost vaccine.
Vaccine 2000;19(1):95-102.
2000: Laurent Kremer; J Estaquier; Isabelle Wolowczuk; Franck Biet; J C Ameisen; Camille Locht
Ineffective cellular immune response associated with T-cell apoptosis in susceptible Mycobacterium bovis BCG-infected mice.
Infection and immunity 2000;68(7):4264-73.
2000: Kevin Pethe; M Aumercier; E Fort; C Gatot; Camille Locht; Franco D Menozzi
Characterization of the heparin-binding site of the mycobacterial heparin-binding hemagglutinin adhesin.
The Journal of biological chemistry 2000;275(19):14273-80.
2000: Philip Supply; E Mazars; Sarah Lesjean; V Vincent; Brigitte Gicquel; Camille Locht
Variable human minisatellite-like regions in the Mycobacterium tuberculosis genome.
Molecular microbiology 2000;36(3):762-71.
2000: Françoise Jacob-Dubuisson; B Kehoe; Eve Willery; Nathalie Reveneau; Camille Locht; D A Relman
Molecular characterization of Bordetella bronchiseptica filamentous haemagglutinin and its secretion machinery.
Microbiology (Reading, England) 2000;146 ( Pt 5)():1211-21.
2000: E Pradel; N Guiso; F D Menozzi; Camille Locht
Bordetella pertussis TonB, a Bvg-independent virulence determinant.
Infection and immunity 2000;68(4):1919-27.
1999: Françoise Jacob-Dubuisson; Chahrazed El Hamel; Nathalie Saint; S Guédin; Eve Willery; Gérard Molle; Camille Locht
Channel formation by FhaC, the outer membrane protein involved in the secretion of the Bordetella pertussis filamentous hemagglutinin.
The Journal of biological chemistry 1999;274(53):37731-5.
1999: B Abomoelak; K Huygen; Laurent Kremer; M Turneer; Camille Locht
Humoral and cellular immune responses in mice immunized with recombinant Mycobacterium bovis Bacillus Calmette-Guérin producing a pertussis toxin-tetanus toxin hybrid protein.
Infection and immunity 1999;67(10):5100-5.
1999: Laurent Kremer; L Dupré; Isabelle Wolowczuk; Camille Locht
In vivo immunomodulation following intradermal injection with DNA encoding IL-18.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(6):3226-31.
1999: Camille Locht
Molecular aspects of Bordetella pertussis pathogenesis.
International microbiology : the official journal of the Spanish Society for Microbiology 1999;2(3):137-44.
1999: P Supply; P Sutton; S N Coughlan; K Bilo; E Saman; A J Trees; M F Cesbron Delauw; Camille Locht
Immunogenicity of recombinant BCG producing the GRA1 antigen from Toxoplasma gondii.
Vaccine 1999;17(7-8):705-14.
1998: Ranjana Srivastava; DK Deb; Kishore K Srivastava; Camille Locht; Brahm S Srivastava
Green fluorescent protein as a reporter in rapid screening of antituberculosis compounds in vitro and in macrophages.
Biochemical and biophysical research communications 1998;253(2):431-6.
1998: Laurent Kremer; L Dupré; Gilles Riveau; André Capron; Camille Locht
Systemic and mucosal immune responses after intranasal administration of recombinant Mycobacterium bovis bacillus Calmette-Guérin expressing glutathione S-transferase from Schistosoma haematobium.
Infection and immunity 1998;66(12):5669-76.
1998: Franco D Menozzi; R Bischoff; E Fort; Michael J Brennan; Camille Locht
Molecular characterization of the mycobacterial heparin-binding hemagglutinin, a mycobacterial adhesin.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(21):12625-30.
1998: J Magdalena; P Supply; Camille Locht
Specific differentiation between Mycobacterium bovis BCG and virulent strains of the Mycobacterium tuberculosis complex.
Journal of clinical microbiology 1998;36(9):2471-6.
1998: S Guédin; Eve Willery; Camille Locht; Françoise Jacob-Dubuisson
Evidence that a globular conformation is not compatible with FhaC-mediated secretion of the Bordetella pertussis filamentous haemagglutinin.
Molecular microbiology 1998;29(3):763-74.
1998: C Lambert-Buisine; Eve Willery; Camille Locht; Françoise Jacob-Dubuisson
N-terminal characterization of the Bordetella pertussis filamentous haemagglutinin.
Molecular microbiology 1998;28(6):1283-93.
1998: Nathalie Mielcarek; Gilles Riveau; Franck Remoué; Rudy Antoine; André Capron; Camille Locht
Homologous and heterologous protection after single intranasal administration of live attenuated recombinant Bordetella pertussis.
Nature biotechnology 1998;16(5):454-7.
1998: J Magdalena; A Vachée; P Supply; Camille Locht
Identification of a new DNA region specific for members of Mycobacterium tuberculosis complex.
Journal of clinical microbiology 1998;36(4):937-43.
1998: POULAIN-GODEFROY Odile; Nathalie Mielcarek; N Ivanoff; Franck Remoué; Anne-Marie Schacht; N Phillips; Camille Locht; André Capron; Gilles Riveau
Bordetella pertussis filamentous hemagglutinin enhances the immunogenicity of liposome-delivered antigen administered intranasally.
Infection and immunity 1998;66(4):1764-7.
1998: E Pradel; N Guiso; Camille Locht
Identification of AlcR, an AraC-type regulator of alcaligin siderophore synthesis in Bordetella bronchiseptica and Bordetella pertussis.
Journal of bacteriology 1998;180(4):871-80.
1998: Gilles Riveau; POULAIN-GODEFROY Odile; L Dupré; Franck Remoué; Nathalie Mielcarek; Camille Locht; André Capron
Glutathione S-transferases of 28kDa as major vaccine candidates against schistosomiasis.
Memórias do Instituto Oswaldo Cruz 1998;93 Suppl 1():87-94.
1997: P Supply; J Magdalena; S Himpens; Camille Locht
Identification of novel intergenic repetitive units in a mycobacterial two-component system operon.
Molecular microbiology 1997;26(5):991-1003.
1997: Laurent Kremer; Jérôme Estaquier; E Brandt; Jean-Claude Ameisen; Camille Locht
Mycobacterium bovis Bacillus Calmette Guérin infection prevents apoptosis of resting human monocytes.
European journal of immunology 1997;27(9):2450-6.
1997: E Leininger; S Bowen; G Renauld-Mongénie; J H Rouse; Franco D Menozzi; Camille Locht; I Heron; Michael J Brennan
Immunodominant domains present on the Bordetella pertussis vaccine component filamentous hemagglutinin.
The Journal of infectious diseases 1997;175(6):1423-31.
1997: Franck Remoué; POULAIN-GODEFROY Odile; Nathalie Mielcarek; R Pierce; André Capron; Camille Locht; Gilles Riveau
Local transient induction of inflammatory cytokines after intranasal administration of recombinant Bordetella pertussis.
Microbial pathogenesis 1997;22(5):305-13.
1997: Nathalie Mielcarek; Jocelyne Cornette; Anne-Marie Schacht; R J Pierce; Camille Locht; André Capron; Gilles Riveau
Intranasal priming with recombinant Bordetella pertussis for the induction of a systemic immune response against a heterologous antigen.
Infection and immunity 1997;65(2):544-50.
1997: Françoise Jacob-Dubuisson; C Buisine; Eve Willery; Geneviève Renauld-Mongénie; Camille Locht
Lack of functional complementation between Bordetella pertussis filamentous hemagglutinin and Proteus mirabilis HpmA hemolysin secretion machineries.
Journal of bacteriology 1997;179(3):775-83.
1996: Alain Baulard; Laurent Kremer; P Supply; D Vidaud; J M Bidart; D Bellet; Camille Locht
A new series of mycobacterial expression vectors for the development of live recombinant vaccines.
Gene 1996;176(1-2):149-54.
1996: Franco D Menozzi; J H Rouse; M Alavi; M Laude-Sharp; J Muller; R Bischoff; Michael J Brennan; Camille Locht
Identification of a heparin-binding hemagglutinin present in mycobacteria.
The Journal of experimental medicine 1996;184(3):993-1001.
1996: G Renauld-Mongénie; Nathalie Mielcarek; J Cornette; Anne-Marie Schacht; André Capron; Gilles Riveau; Camille Locht
Induction of mucosal immune responses against a heterologous antigen fused to filamentous hemagglutinin after intranasal immunization with recombinant Bordetella pertussis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7944-9.
1996: Laurent Kremer; Gilles Riveau; Alain Baulard; André Capron; Camille Locht
Neutralizing antibody responses elicited in mice immunized with recombinant bacillus Calmette-Guérin producing the Schistosoma mansoni glutathione S-transferase.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(11):4309-17.
1996: Alain Baulard; Laurent Kremer; Camille Locht
Efficient homologous recombination in fast-growing and slow-growing mycobacteria.
Journal of bacteriology 1996;178(11):3091-8.
1996: G Renauld-Mongénie; J Cornette; Nathalie Mielcarek; Franco D Menozzi; Camille Locht
Distinct roles of the N-terminal and C-terminal precursor domains in the biogenesis of the Bordetella pertussis filamentous hemagglutinin.
Journal of bacteriology 1996;178(4):1053-60.
1996: Françoise Jacob-Dubuisson; C Buisine; Nathalie Mielcarek; E Clément; Franco D Menozzi; Camille Locht
Amino-terminal maturation of the Bordetella pertussis filamentous haemagglutinin.
Molecular microbiology 1996;19(1):65-78.
1995: Laurent Kremer; Alain Baulard; Jérôme Estaquier; POULAIN-GODEFROY Odile; Camille Locht
Green fluorescent protein as a new expression marker in mycobacteria.
Molecular microbiology 1995;17(5):913-22.
1995: Alain Baulard; V Escuyer; N Haddad; Laurent Kremer; Camille Locht; P Berche
Mercury resistance as a selective marker for recombinant mycobacteria.
Microbiology (Reading, England) 1995;141 ( Pt 4)():1045-50.
1995: Laurent Kremer; Alain Baulard; Jérôme Estaquier; J Content; André Capron; Camille Locht
Analysis of the Mycobacterium tuberculosis 85A antigen promoter region.
Journal of bacteriology 1995;177(3):642-53.
1995: Camille Locht; R Antoine
A proposed mechanism of ADP-ribosylation catalyzed by the pertussis toxin S1 subunit.
Biochimie 1995;77(5):333-40.
1994: J H Hannah; Franco D Menozzi; G Renauld; Camille Locht; Michael J Brennan
Sulfated glycoconjugate receptors for the Bordetella pertussis adhesin filamentous hemagglutinin (FHA) and mapping of the heparin-binding domain on FHA.
Infection and immunity 1994;62(11):5010-9.
1994: Franco D Menozzi; P E Boucher; Gilles Riveau; C Gantiez; Camille Locht
Surface-associated filamentous hemagglutinin induces autoagglutination of Bordetella pertussis.
Infection and immunity 1994;62(10):4261-9.
1994: P E Boucher; Franco D Menozzi; Camille Locht
The modular architecture of bacterial response regulators. Insights into the activation mechanism of the BvgA transactivator of Bordetella pertussis.
Journal of molecular biology 1994;241(3):363-77.
1994: R Antoine; Camille Locht
The NAD-glycohydrolase activity of the pertussis toxin S1 subunit. Involvement of the catalytic HIS-35 residue.
The Journal of biological chemistry 1994;269(9):6450-7.
1994: Franco D Menozzi; R Mutombo; G Renauld; C Gantiez; J H Hannah; E Leininger; Michael J Brennan; Camille Locht
Heparin-inhibitable lectin activity of the filamentous hemagglutinin adhesin of Bordetella pertussis.
Infection and immunity 1994;62(3):769-78.
1994: P Boucher; H Sato; Y Sato; Camille Locht
Neutralizing antibodies and immunoprotection against pertussis and tetanus obtained by use of a recombinant pertussis toxin-tetanus toxin fusion protein.
Infection and immunity 1994;62(2):449-56.
1994: Rob Willems; C Geuijen; Han G J van der Heide; G Renauld; P Bertin; Willem van den Akker; Camille Locht; Frits R Mooi
Mutational analysis of the Bordetella pertussis fim/fha gene cluster: identification of a gene with sequence similarities to haemolysin accessory genes involved in export of FHA.
Molecular microbiology 1994;11(2):337-47.
1993: R Antoine; A Tallett; S van Heyningen; Camille Locht
Evidence for a catalytic role of glutamic acid 129 in the NAD-glycohydrolase activity of the pertussis toxin S1 subunit.
The Journal of biological chemistry 1993;268(32):24149-55.
1993: Camille Locht; P Bertin; Franco D Menozzi; G Renauld
The filamentous haemagglutinin, a multifaceted adhesion produced by virulent Bordetella spp.
Molecular microbiology 1993;9(4):653-60.
1993: Yves Lobet; C Feron; G Dequesne; E Simoen; P Hauser; Camille Locht
Site-specific alterations in the B oligomer that affect receptor-binding activities and mitogenicity of pertussis toxin.
The Journal of experimental medicine 1993;177(1):79-87.
1992: Camille Locht; M C Geoffroy; G Renauld
Common accessory genes for the Bordetella pertussis filamentous hemagglutinin and fimbriae share sequence similarities with the papC and papD gene families.
The EMBO journal 1992;11(9):3175-83.
1992: Alain Baulard; C Jourdan; A Mercenier; Camille Locht
Rapid mycobacterial plasmid analysis by electroduction between Mycobacterium spp. and Escherichia coli.
Nucleic acids research 1992;20(15):4105.
1992: R Antoine; Camille Locht
Isolation and molecular characterization of a novel broad-host-range plasmid from Bordetella bronchiseptica with sequence similarities to plasmids from gram-positive organisms.
Molecular microbiology 1992;6(13):1785-99.
1991: Franco D Menozzi; C Gantiez; Camille Locht
Identification and purification of transferrin- and lactoferrin-binding proteins of Bordetella pertussis and Bordetella bronchiseptica.
Infection and immunity 1991;59(11):3982-8.
1991: Franco D Menozzi; C Gantiez; Camille Locht
Interaction of the Bordetella pertussis filamentous hemagglutinin with heparin.
FEMS microbiology letters 1991;62(1):59-64.
1990: A M Delisse-Gathoye; Camille Locht; F Jacob; M Raaschou-Nielsen; I Heron; J L Ruelle; Michel Jean De Wilde; T Cabezon
Cloning, partial sequence, expression, and antigenic analysis of the filamentous hemagglutinin gene of Bordetella pertussis.
Infection and immunity 1990;58(9):2895-905.
1990: W Cieplak; Camille Locht; V L Mar; W Neal Burnette; J M Keith
Photolabelling of mutant forms of the S1 subunit of pertussis toxin with NAD+.
The Biochemical journal 1990;268(3):547-51.
1990: R Antoine; Camille Locht
Roles of the disulfide bond and the carboxy-terminal region of the S1 subunit in the assembly and biosynthesis of pertussis toxin.
Infection and immunity 1990;58(6):1518-26.
1990: Camille Locht; Yves Lobet; C Feron; W Cieplak; J M Keith
The role of cysteine 41 in the enzymatic activities of the pertussis toxin S1 subunit as investigated by site-directed mutagenesis.
The Journal of biological chemistry 1990;265(8):4552-9.
1989: Camille Locht; Carine Capiau; C Feron
Identification of amino acid residues essential for the enzymatic activities of pertussis toxin.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(9):3075-9.
1987: Camille Locht; W Cieplak; K S Marchitto; H Sato; J M Keith
Activities of complete and truncated forms of pertussis toxin subunits S1 and S2 synthesized by Escherichia coli.
Infection and immunity 1987;55(11):2546-53.
1987: Camille Locht; J M Keith
Can pertussis be eradicated by vaccination?
Lancet 1987;1(8535):738.
1987: K S Marchitto; S G Smith; Camille Locht; J M Keith
Nucleotide sequence homology to pertussis toxin gene in Bordetella bronchiseptica and Bordetella parapertussis.
Infection and immunity 1987;55(3):497-501.
1986: Camille Locht; B Chesebro; R Race; J M Keith
Molecular cloning and complete sequence of prion protein cDNA from mouse brain infected with the scrapie agent.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(17):6372-6.
1986: Camille Locht; J M Keith
Pertussis toxin gene: nucleotide sequence and genetic organization.
Science (New York, N.Y.) 1986;232(4755):1258-64.
1986: Camille Locht; P A Barstad; J E Coligan; L Mayer; J J Munoz; S G Smith; J M Keith
Molecular cloning of pertussis toxin genes.
Nucleic acids research 1986;14(8):3251-61.