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David Loebenberg

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Shu-Wei Yang; Tze-Ming Chan; Joseph Terracciano; David Loebenberg; Mahesh Patel; Vincent Gullo; Min Chu
Sch 1385568, a new azaphilone from Aspergillus sp.
Shu-Wei Yang; Tze-Ming Chan; Joseph Terracciano; Eric Boehm; Reena Patel; Guodong Chen; David Loebenberg; Mahesh Patel; Vincent Gullo; Birendra Pramanik; Min Chu
Caryophyllenes from a fungal culture of Chrysosporium pilosum.
Amin A Nomeir; Birendra Pramanik; Larry Heimark; Frank Bennett; John Veals; Peter L Bartner; Maryjane Hilbert; Anil K Saksena; Paul McNamara; Viyyoor Girijavallabhan; Ashit K Ganguly; Raymond G Lovey; Russell Pike; Haiyan Wang; Yi-Tsung Liu; Pramila Kumari; Walter A Korfmacher; Chin-Chung Lin; Anthony Cacciapuoti; David Loebenberg; Roberta S Hare; George Miller; Cecil Pickett
Posaconazole (Noxafil, SCH 56592), a new azole antifungal drug, was a discovery based on the isolation and mass spectral characterization of a circulating metabolite of an earlier lead (SCH 51048).

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All Publications

2009: Shu-Wei Yang; Tze-Ming Chan; Joseph Terracciano; David Loebenberg; Mahesh Patel; Vincent Gullo; Min Chu
Sch 1385568, a new azaphilone from Aspergillus sp.
The Journal of antibiotics 2009;62(7):401-3.
2009: Shu-Wei Yang; Tze-Ming Chan; Joseph Terracciano; Eric Boehm; Reena Patel; Guodong Chen; David Loebenberg; Mahesh Patel; Vincent Gullo; Birendra Pramanik; Min Chu
Caryophyllenes from a fungal culture of Chrysosporium pilosum.
Journal of natural products 2009;72(3):484-7.
2008: Amin A Nomeir; Birendra Pramanik; Larry Heimark; Frank Bennett; John Veals; Peter L Bartner; Maryjane Hilbert; Anil K Saksena; Paul McNamara; Viyyoor Girijavallabhan; Ashit K Ganguly; Raymond G Lovey; Russell Pike; Haiyan Wang; Yi-Tsung Liu; Pramila Kumari; Walter A Korfmacher; Chin-Chung Lin; Anthony Cacciapuoti; David Loebenberg; Roberta S Hare; George Miller; Cecil Pickett
Posaconazole (Noxafil, SCH 56592), a new azole antifungal drug, was a discovery based on the isolation and mass spectral characterization of a circulating metabolite of an earlier lead (SCH 51048).
Journal of mass spectrometry : JMS 2008;43(4):509-17.
2006: Anthony Cacciapuoti; Judith Halpern; Cara A Mendrick; Christine Norris; Reena Patel; David Loebenberg
Interaction between posaconazole and caspofungin in concomitant treatment of mice with systemic Aspergillus infection.
Antimicrobial agents and chemotherapy 2006;50(7):2587-90.
2006: Frank J Sabatelli; Reena Patel; Paul A Mann; Cara A Mendrick; C C Norris; Roberta S Hare; David Loebenberg; Todd A Black; Paul M McNicholas
In vitro activities of posaconazole, fluconazole, itraconazole, voriconazole, and amphotericin B against a large collection of clinically important molds and yeasts.
Antimicrobial agents and chemotherapy 2006;50(6):2009-15.
2006: Shu-Wei Yang; Tze-Ming Chan; Joseph Terracciano; David Loebenberg; Mahesh Patel; Vincent Gullo; Min Chu
A new 5-alkenylresorcinol sch 725681 from Aspergillus sp.
The Journal of antibiotics 2006;59(3):190-2.
2006: Frank Bennett; Anil K Saksena; Raymond G Lovey; Yi-Tsung Liu; Naginbhai M Patel; Patrick Pinto; Russel Pike; Edwin Jao; Viyyoor Girijavallabhan; Ashit K Ganguly; David Loebenberg; Haiyan Wang; Anthony Cacciapuoti; Eugene Moss; Frederick Menzel; Roberta S Hare; Amin A Nomeir
Hydroxylated analogues of the orally active broad spectrum antifungal, Sch 51048 (1), and the discovery of posaconazole [Sch 56592; 2 or (S,S)-5].
Bioorganic & medicinal chemistry letters 2006;16(1):186-90.
2005: Kimberly Vinette Herrin; Abraham Miranda; David Loebenberg
Posaconazole therapy for systemic coccidioidomycosis in a chimpanzee (Pan troglodytes): a case report.
Mycoses 2005;48(6):447-52.
2005: Shu-Wei Yang; Tze-Ming Chan; Joseph Terracciano; David Loebenberg; Mahesh Patel; Min Chu
Structure elucidation of Sch 725674 from Aspergillus sp.
The Journal of antibiotics 2005;58(8):535-8.
2005: Gloria M González; Annette W Fothergill; Deanna A Sutton; Michael G Rinaldi; David Loebenberg
In vitro activities of new and established triazoles against opportunistic filamentous and dimorphic fungi.
Medical mycology : official publication of the International Society for Human and Animal Mycology 2005;43(3):281-4.
2005: Shu-Wei Yang; Tze-Ming Chan; Joseph Terracciano; Reena Patel; David Loebenberg; Guodong Chen; Mahesh Patel; Vincent Gullo; Birendra Pramanik; Min Chu
New antibiotic Sch 725424 and its dehydration product Sch 725428 from Kitasatospora sp.
The Journal of antibiotics 2005;58(3):192-5.
2005: Alfonso Carrillo-Muñoz; Guillermo Quindos; María Teresa Ruesga; Rocío Alonso; Oscar del Valle; Juan Manuel Hernández-Molina; Paul M McNicholas; David Loebenberg; Patricia Santos
Antifungal activity of posaconazole compared with fluconazole and amphotericin B against yeasts from oropharyngeal candidiasis and other infections.
The Journal of antimicrobial chemotherapy 2005;55(3):317-9.
2005: Anthony Cacciapuoti; Maya Gurnani; Judith Halpern; Christine Norris; Reena Patel; David Loebenberg
Interaction between posaconazole and amphotericin B in concomitant treatment against Candida albicans in vivo.
Antimicrobial agents and chemotherapy 2005;49(2):638-42.
2004: Hanan K Munayyer; Paul A Mann; Andrew S Chau; Taisa Yarosh-Tomaine; Jonathan R Greene; Roberta S Hare; Larry Heimark; Robert E Palermo; David Loebenberg; Paul M McNicholas
Posaconazole is a potent inhibitor of sterol 14alpha-demethylation in yeasts and molds.
Antimicrobial agents and chemotherapy 2004;48(10):3690-6.
2004: Shu-Wei Yang; Tze-Ming Chan; Joseph Terracciano; Reena Patel; David Loebenberg; Guodong Chen; Mahesh Patel; Vincent Gullo; Birendra Pramanik; Min Chu
A new anthracycline antibiotic micromonomycin from Micromonospora sp.
The Journal of antibiotics 2004;57(9):601-4.
2004: Andriani C Patera; Frederick Menzel; Craig Jackson; Joan K Brieland; Judith Halpern; Roberta S Hare; Anthony Cacciapuoti; David Loebenberg
Effect of granulocyte colony-stimulating factor combination therapy on efficacy of posaconazole (SCH56592) in an inhalation model of murine pulmonary aspergillosis.
Antimicrobial agents and chemotherapy 2004;48(8):3154-8.
2004: Shu-Wei Yang; Tze-Ming Chan; Reena Patel; Joseph Terracciano; David Loebenberg; Mahesh Patel; Min Chu
A new antimicrobial dibenzofuran Sch 725421 from an unidentified fungus.
The Journal of antibiotics 2004;57(7):465-7.
2004: John Graybill; Laura K Najvar; Elizabeth Johnson; Rosie Bocanegra; David Loebenberg
Posaconazole therapy of disseminated phaeohyphomycosis in a murine model.
Antimicrobial agents and chemotherapy 2004;48(6):2288-91.
2004: Andrew S Chau; Cara A Mendrick; Frank J Sabatelli; David Loebenberg; Paul M McNicholas
Application of real-time quantitative PCR to molecular analysis of Candida albicans strains exhibiting reduced susceptibility to azoles.
Antimicrobial agents and chemotherapy 2004;48(6):2124-31.
2004: Shu-Wei Yang; Tze-Ming Chian; Joseph Terracciano; David Loebenberg; Guodong Chen; Mathesh Patel; Vincent Gullo; Birendra Pramanik; Min Chu
Structure elucidation of a new diketopiperazine Sch 725418 from Micromonospora sp.
The Journal of antibiotics 2004;57(5):345-7.
2004: Laura K Najvar; Anthony Cacciapuoti; Steve Hernandez; Judith Halpern; Rosie Bocanegra; Maya Gurnani; Frederick Menzel; David Loebenberg; John Graybill
Activity of posaconazole combined with amphotericin B against Aspergillus flavus infection in mice: comparative studies in two laboratories.
Antimicrobial agents and chemotherapy 2004;48(3):758-64.
2004: Li Xiao; Vincent Madison; Andrew S Chau; David Loebenberg; Robert E Palermo; Paul M McNicholas
Three-dimensional models of wild-type and mutated forms of cytochrome P450 14alpha-sterol demethylases from Aspergillus fumigatus and Candida albicans provide insights into posaconazole binding.
Antimicrobial agents and chemotherapy 2004;48(2):568-74.
2004: David Andes; Karen Marchillo; R Conklin; Gopal Krishna; Farkad Ezzet; Anthony Cacciapuoti; David Loebenberg
Pharmacodynamics of a new triazole, posaconazole, in a murine model of disseminated candidiasis.
Antimicrobial agents and chemotherapy 2004;48(1):137-42.
2004: Xin Li; Nathaniel Brown; Andrew S Chau; José L López-Ribot; María Teresa Ruesga; Guillermo Quindos; Cara A Mendrick; Roberta S Hare; David Loebenberg; Beth DiDomenico; Paul M McNicholas
Changes in susceptibility to posaconazole in clinical isolates of Candida albicans.
The Journal of antimicrobial chemotherapy 2004;53(1):74-80.
2003: Eric Dannaoui; Jacques Meis; David Loebenberg; Paul E Verweij
Activity of posaconazole in treatment of experimental disseminated zygomycosis.
Antimicrobial agents and chemotherapy 2003;47(11):3647-50.
2003: Vinod R Hegde; Jack Silver; Mahesh Patel; Vincent Gullo; Mohindar S Puar; Pradip R Das; David Loebenberg
Novel fungal metabolites as cell wall active antifungals: fermentation, isolation, physico-chemical properties, structure and biological activity.
The Journal of antibiotics 2003;56(5):437-47.
2003: Shu-Wei Yang; Alexei V Buevich; Tze-Ming Chan; Joseph Terracciano; Guodong Chen; David Loebenberg; Mahesh Patel; Eric Boehm; Vincent Gullo; Birendra Pramanik; Min Chu
A new antifungal sterol sulfate, Sch 601324, from Chrysosporium sp.
The Journal of antibiotics 2003;56(4):419-22.
2003: Gloria M González; Rolando Tijerina; Laura K Najvar; Rosie Bocanegra; Michael G Rinaldi; David Loebenberg; John Graybill
Activity of posaconazole against Pseudallescheria boydii: in vitro and in vivo assays.
Antimicrobial agents and chemotherapy 2003;47(4):1436-8.
2003: Shu-Wei Yang; Tze-Ming Chan; Shirley A Pomponi; Guodong Chen; David Loebenberg; Amy E Wright; Mahesh Patel; Vincent Gullo; Birendra Pramanik; Min Chu
Structure elucidation of a new antifungal sterol sulfate, Sch 575867, from a deep-water marine sponge (Family: Astroscleridae).
The Journal of antibiotics 2003;56(2):186-9.
2003: Paul A Mann; Raulo M Parmegiani; Shui-Qing Wei; Cara A Mendrick; Xin Li; David Loebenberg; Beth DiDomenico; Roberta S Hare; Scott S Walker; Paul M McNicholas
Mutations in Aspergillus fumigatus resulting in reduced susceptibility to posaconazole appear to be restricted to a single amino acid in the cytochrome P450 14alpha-demethylase.
Antimicrobial agents and chemotherapy 2003;47(2):577-81.
2002: Raymond G Lovey; Anil K Saksena; Viyyoor Girijavallabhan; Paul Blundell; Henry Guzik; David Loebenberg; Raulo M Parmegiani; Anthony Cacciapuoti
Synthesis and antifungal activity of the 2,2,5-tetrahydrofuran regioisomers of SCH 51048.
Bioorganic & medicinal chemistry letters 2002;12(13):1739-42.
2002: Qiu N Sun; Laura K Najvar; Rosie Bocanegra; David Loebenberg; John Graybill
In vivo activity of posaconazole against Mucor spp. in an immunosuppressed-mouse model.
Antimicrobial agents and chemotherapy 2002;46(7):2310-2.
2002: Gloria M González; Rolando Tijerina; Laura K Najvar; Rosie Bocanegra; Michael Rinaldi; David Loebenberg; John Graybill
In vitro and in vivo activities of posaconazole against Coccidioides immitis.
Antimicrobial agents and chemotherapy 2002;46(5):1352-6.
2001: Paul A Mann; Liqun Xiong; Alexander S Mankin; Andrew S Chau; Cara A Mendrick; DJ Najarian; C A Cramer; David Loebenberg; Elizabeth Coates; Nicholas J Murgolo; F M Aarestrup; Richard Goering; Todd A Black; Roberta S Hare; Paul M McNicholas
EmtA, a rRNA methyltransferase conferring high-level evernimicin resistance.
Molecular microbiology 2001;41(6):1349-56.
2001: Joan K Brieland; D Essig; Craig Jackson; D Frank; David Loebenberg; Frederick Menzel; B Arnold; Beth DiDomenico; Roberta S Hare
Comparison of pathogenesis and host immune responses to Candida glabrata and Candida albicans in systemically infected immunocompetent mice.
Infection and immunity 2001;69(8):5046-55.
2001: Shmuel Zbaida; Joan K Brieland; Philip A Krieter; David Loebenberg; Gopal Krishna; D Horne; X Lu; Yuan Yuan; Roberta S Hare; Mitchell N Cayen; James E Patrick
In vitro uptake of SCH 27899 (evernimicin) by rat alveolar macrophages.
Antimicrobial agents and chemotherapy 2001;45(3):959-61.
2001: Joan K Brieland; Craig Jackson; Frederick Menzel; David Loebenberg; Anthony Cacciapuoti; Judith Halpern; S Hurst; Tony Muchamuel; R Debets; Robert A Kastelein; Tatyana Churakova; Jon Abrams; Roberta S Hare; Anne O'Garra
Cytokine networking in lungs of immunocompetent mice in response to inhaled Aspergillus fumigatus.
Infection and immunity 2001;69(3):1554-60.
2001: Vinod R Hegde; Jack Silver; Mahesh Patel; Vincent Gullo; R Yarborough; E Huang; Pradip R Das; Mohindar S Puar; Beth DiDomenico; David Loebenberg
Novel fungal metabolites as cell wall active antifungals: fermentation, isolation, physico-chemical properties, structure and biological activity.
The Journal of antibiotics 2001;54(1):74-83.
2000: Joan K Brieland; Craig Jackson; S Hurst; David Loebenberg; Tony Muchamuel; R Debets; Robert A Kastelein; Tatyana Churakova; Jon Abrams; Roberta S Hare; Anne O'Garra
Immunomodulatory role of endogenous interleukin-18 in gamma interferon-mediated resolution of replicative Legionella pneumophila lung infection.
Infection and immunity 2000;68(12):6567-73.
2000: P V Adrian; Cara A Mendrick; David Loebenberg; Paul M McNicholas; KJ Shaw; keith klugman; Roberta S Hare; Todd A Black
Evernimicin (SCH27899) inhibits a novel ribosome target site: analysis of 23S ribosomal DNA mutants.
Antimicrobial agents and chemotherapy 2000;44(11):3101-6.
2000: Elias K Manavathu; Jessica L Cutright; David Loebenberg; Pranatharthi H Chandrasekar
A comparative study of the in vitro susceptibilities of clinical and laboratory-selected resistant isolates of Aspergillus spp. to amphotericin B, itraconazole, voriconazole and posaconazole (SCH 56592).
The Journal of antimicrobial chemotherapy 2000;46(2):229-34.
2000: Anthony Cacciapuoti; David Loebenberg; E Corcoran; Frederick Menzel; Eugene Moss; Christine Norris; M Michalski; K Raynor; Judith Halpern; Cara A Mendrick; B Arnold; B Antonacci; Raulo M Parmegiani; Taisa Yarosh-Tomaine; GH Miller; Roberta S Hare
In vitro and in vivo activities of SCH 56592 (posaconazole), a new triazole antifungal agent, against Aspergillus and Candida.
Antimicrobial agents and chemotherapy 2000;44(8):2017-22.
2000: Joan K Brieland; David Loebenberg; Frederick Menzel; Roberta S Hare
Efficacy of SCH27899 in an animal model of Legionnaires' disease using immunocompromised A/J mice.
Antimicrobial agents and chemotherapy 2000;44(5):1333-6.
2000: Hail M Al-Abdely; Laura K Najvar; Rosie Bocanegra; Annette W Fothergill; David Loebenberg; Michael G Rinaldi; John Graybill
SCH 56592, amphotericin B, or itraconazole therapy of experimental murine cerebral phaeohyphomycosis due to Ramichloridium obovoideum ("Ramichloridium mackenziei").
Antimicrobial agents and chemotherapy 2000;44(5):1159-62.
2000: C Lin; S Gupta; David Loebenberg; Mitchell N Cayen
Pharmacokinetics of an everninomicin (SCH 27899) in mice, rats, rabbits, and cynomolgus monkeys following intravenous administration.
Antimicrobial agents and chemotherapy 2000;44(4):916-9.
2000: William R Kirkpatrick; Robert K McAtee; Annette W Fothergill; David Loebenberg; Michael G Rinaldi; Thomas Patterson
Efficacy of SCH56592 in a rabbit model of invasive aspergillosis.
Antimicrobial agents and chemotherapy 2000;44(3):780-2.
2000: Amin A Nomeir; Pramila Kumari; Mary Jane Hilbert; S Gupta; David Loebenberg; Anthony Cacciapuoti; Roberta S Hare; GH Miller; Chin-Chung Lin; Mitchell N Cayen
Pharmacokinetics of SCH 56592, a new azole broad-spectrum antifungal agent, in mice, rats, rabbits, dogs, and cynomolgus monkeys.
Antimicrobial agents and chemotherapy 2000;44(3):727-31.
1999: Hail M Al-Abdely; John Graybill; David Loebenberg; Peter C Melby
Efficacy of the triazole SCH 56592 against Leishmania amazonensis and Leishmania donovani in experimental murine cutaneous and visceral leishmaniases.
Antimicrobial agents and chemotherapy 1999;43(12):2910-4.
1998: John Graybill; Rosie Bocanegra; Laura K Najvar; MF Luther; David Loebenberg
SCH56592 treatment of murine invasive aspergillosis.
The Journal of antimicrobial chemotherapy 1998;42(4):539-42.
1998: John Graybill; Rosie Bocanegra; Laura K Najvar; David Loebenberg; MF Luther
Granulocyte colony-stimulating factor and azole antifungal therapy in murine aspergillosis: role of immune suppression.
Antimicrobial agents and chemotherapy 1998;42(10):2467-73.
1998: Vinod R Hegde; Mahesh G Patel; Ann C Horan; A H King; F Gentile; Mohindar S Puar; David Loebenberg
A novel macrolactam-trisaccharide antifungal antibiotic. Taxonomy, fermentation, isolation, physico-chemical properties, structure elucidation and biological activity.
The Journal of antibiotics 1998;51(5):464-70.
1997: Min Chu; I Truumees; Ronald Mierzwa; Joseph Terracciano; Mahesh Patel; David Loebenberg; James J Kaminski; Pradip Das; Mohindar S Puar
Sch 54445: a new polycyclic xanthone with highly potent antifungal activity produced by Actinoplanes sp.
Journal of natural products 1997;60(5):525-8.
1995: R Allendoerfer; David Loebenberg; Michael G Rinaldi; John Graybill
Evaluation of SCH51048 in an experimental model of pulmonary aspergillosis.
Antimicrobial agents and chemotherapy 1995;39(6):1345-8.
1993: Vinod R Hegde; M G Patel; V P Gullo; Ann C Horan; A H King; F Gentile; G H Wagman; Mohindar S Puar; David Loebenberg
A novel macrolactam-disaccharide antifungal antibiotic. Taxonomy, fermentation, isolation, physico-chemical properties, structure elucidation and biological activity.
The Journal of antibiotics 1993;46(7):1109-15.
1993: L Wearley; B Antonacci; A Cacciapuoti; S Assenza; I Chaudry; C Eckhart; N Levine; David Loebenberg; C Norris; R Parmegiani
Relationship among physicochemical properties, skin permeability, and topical activity of the racemic compound and pure enantiomers of a new antifungal.
Pharmaceutical research 1993;10(1):136-40.
1993: R M Parmegiani; David Loebenberg; A Cacciapuoti; B Antonacci; C Norris; F Menzel; L Moss; T Yarosh-Tomaine; Roberta S Hare; GH Miller
Sch 39304, a new antifungal agent: oral and topical treatment of vaginal and superficial infections.
Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology 1993;31(3):239-48.
1992: R G Lovey; A J Elliott; James J Kaminski; David Loebenberg; R M Parmegiani; D F Rane; Viyyoor Girijavallabhan; R E Pike; H Guzik; B Antonacci
Isobenzofurans as conformationally constrained miconazole analogues with improved antifungal potency.
Journal of medicinal chemistry 1992;35(22):4221-9.
1992: R Cooper; I Truumees; R Yarborough; David Loebenberg; J Marquez; Ann C Horan; Mahesh Patel; V Gullo; Mohindar S Puar; B Pramanik
Macrolactams: two novel homologous series of compounds produced by Actinomadura sp. SCC 1778.
The Journal of antibiotics 1992;45(5):633-8.
1992: Vinod R Hegde; Mahesh Patel; Ann C Horan; V Gullo; J Marquez; I Gunnarsson; F Gentile; David Loebenberg; A King; Mohindar S Puar
Macrolactams: a novel class of antifungal antibiotics produced by Actinomadura spp. SCC 1776 and SCC 1777.
The Journal of antibiotics 1992;45(5):624-32.
1992: R Cooper; I Truumees; I Gunnarsson; David Loebenberg; Ann C Horan; J Marquez; Mahesh Patel; V Gullo; Mohindar S Puar; Pradip Das
Sch 42137, a novel antifungal antibiotic from an Actinoplanes sp. Fermentation, isolation, structure and biological properties.
The Journal of antibiotics 1992;45(4):444-53.
1992: David Loebenberg; A Cacciapuoti; R Parmegiani; E L Moss; F Menzel; B Antonacci; C Norris; T Yarosh-Tomaine; Roberta S Hare; GH Miller
In vitro and in vivo activities of SCH 42427, the active enantiomer of the antifungal agent SCH 39304.
Antimicrobial agents and chemotherapy 1992;36(2):498-501.
1992: A Cacciapuoti; David Loebenberg; R Parmegiani; B Antonacci; C Norris; E L Moss; F Menzel; T Yarosh-Tomaine; Roberta S Hare; GH Miller
Comparison of SCH 39304, fluconazole, and ketoconazole for treatment of systemic infections in mice.
Antimicrobial agents and chemotherapy 1992;36(1):64-7.
1992: R Allendoerfer; R R Yates; A J Marquis; David Loebenberg; Michael G Rinaldi; John Graybill
Comparison of SCH 39304 and its isomers, RR 42427 and SS 42426, for treatment of murine cryptococcal and coccidioidal meningitis.
Antimicrobial agents and chemotherapy 1992;36(1):217-9.
1990: A F Cacciapuoti; David Loebenberg; E L Moss; F W Menzel; J A Rudeen; L R Naples; C L Cramer; Roberta S Hare; A K Mallams; GH Miller
Microbiological and pharmacokinetic studies of acyl demycinosyltylosin and related tylosin derivatives.
The Journal of antibiotics 1990;43(9):1131-6.
1988: Mahesh Patel; M Conover; Ann C Horan; David Loebenberg; J Marquez; Ronald Mierzwa; Mohindar S Puar; R Yarborough; J A Waitz
Sch 31828, a novel antibiotic from a Microbispora sp.: taxonomy, fermentation, isolation and biological properties.
The Journal of antibiotics 1988;41(6):794-7.
1988: R Cooper; Ann C Horan; F Gentile; V Gullo; David Loebenberg; J Marquez; Mahesh Patel; Mohindar S Puar; I Truumees
Sch 37137, a novel antifungal compound produced by a Micromonospora sp. Taxonomy, fermentation, isolation, structure and biological properties.
The Journal of antibiotics 1988;41(1):13-9.
1988: A B Cooper; J J Wright; Ashit K Ganguly; J Desai; David Loebenberg; R Parmegiani; D S Feingold
Synthesis and antifungal properties of 14-aminomethyl-substituted lanosterol derivatives.
Annals of the New York Academy of Sciences 1988;544():109-12.
1988: D F Rane; J A Desai; David Loebenberg; R Parmegiani; R E Pike
Synthesis and antifungal properties of dihydrobenzothiophene azoles.
Annals of the New York Academy of Sciences 1988;544():105-8.
1987: R M Parmegiani; David Loebenberg; B Antonacci; T Yarosh-Tomaine; R Scupp; J J Wright; P J Chiu; GH Miller
Comparative in vitro and in vivo evaluation of N-D-ornithyl amphotericin B methyl ester, amphotericin B methyl ester, and amphotericin B.
Antimicrobial agents and chemotherapy 1987;31(11):1756-60.
1987: A Cacciapuoti; E L Moss; F Menzel; C A Cramer; W Weiss; David Loebenberg; Roberta S Hare; GH Miller
In vitro and in vivo characterization of novel 8-methoxy derivatives of chlortetracycline.
The Journal of antibiotics 1987;40(10):1426-30.
1987: J Lim; J Schwartz; David Loebenberg; GH Miller; S Symchowicz; C Lin
Evaluation of (+)-cyclaradine-5'-esters as prodrugs for (+)-cyclaradine in animals.
Antimicrobial agents and chemotherapy 1987;31(7):998-1001.
1985: M Chung; Elaine Radwanski; David Loebenberg; C C Lin; E Oden; S Symchowicz; R P Gural; GH Miller
Interspecies pharmacokinetic scaling of Sch 34343.
The Journal of antimicrobial chemotherapy 1985;15 Suppl C():227-33.
1985: C Lin; David Loebenberg; M Chung; E Oden; John Veals; H Kim; J Lim; C Korduba; R D'Souza; E Moss
Pharmacokinetics of Sch 34343 in rats and dogs.
The Journal of antimicrobial chemotherapy 1985;15 Suppl C():219-26.
1985: David Loebenberg; E L Moss; J Rudeen; F Menzel; Roberta S Hare; E M Oden; C C Lin; GH Miller
Evaluation of the in-vivo efficacy of Sch 34343.
The Journal of antimicrobial chemotherapy 1985;15 Suppl C():207-18.
1985: C Adam; L Naples; W Weiss; F Sabatelli; Roberta S Hare; David Loebenberg; GH Miller
Evaluation of the in-vitro antibacterial activity of Sch 34343.
The Journal of antimicrobial chemotherapy 1985;15 Suppl C():39-56.
1984: H Kim; David Loebenberg; A Marco; S Symchowicz; C Lin
Comparative pharmacokinetics of Sch 28191 and amphotericin B in mice, rats, dogs, and cynomolgus monkeys.
Antimicrobial agents and chemotherapy 1984;26(4):446-9.
1984: Mahesh Patel; Vinod R Hegde; Ann C Horan; V P Gullo; David Loebenberg; J A Marquez; GH Miller; Mohindar S Puar; J A Waitz
A novel phenazine antifungal antibiotic, 1,6-dihydroxy-2-chlorophenazine. Fermentation, isolation, structure and biological properties.
The Journal of antibiotics 1984;37(9):943-8.
1984: Mahesh Patel; Ann C Horan; V P Gullo; David Loebenberg; J A Marquez; GH Miller; J A Waitz
Oxanthromicin, a novel antibiotic from Actinomadura.
The Journal of antibiotics 1984;37(4):413-5.
1983: J A Marquez; Ann C Horan; M Kalyanpur; B K Lee; David Loebenberg; GH Miller; Mahesh Patel; J A Waitz
The hazimicins, a new class of antibiotics. Taxonomy, fermentation, isolation, characterization and biological properties.
The Journal of antibiotics 1983;36(9):1101-8.
1982: Roberta S Hare; GH Miller; L Naples; F Sabatelli; David Loebenberg; J A Waitz
Sch 29482, a new penem antibiotic: evaluation of in-vitro activity and effect of test conditions.
The Journal of antimicrobial chemotherapy 1982;9 Suppl C():7-16.
1982: David Loebenberg; GH Miller; E L Moss; E Oden; Roberta S Hare; M Chung; J A Waitz
Evaluation of the in-vitro activity of Sch 29482.
The Journal of antimicrobial chemotherapy 1982;9 Suppl C():221-31.
1981: J A Waitz; Ann C Horan; M Kalyanpur; B K Lee; David Loebenberg; J A Marquez; G Miller; M G Patel
Kijanimicin (Sch 25663), a novel antibiotic produced by Actinomadura kijaniata SCC 1256. Fermentation, isolation, characterization and biological properties.
The Journal of antibiotics 1981;34(9):1101-6.
1980: David Loebenberg; R Parmegiani; M Hanks; J A Waitz
Comparative in vitro and in vivo antifungal activity of tolnaftate and various undecylenates.
Journal of pharmaceutical sciences 1980;69(6):739-41.