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Thorsteinn Loftsson
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26
Másson, Már
14
Stefánsson, Einar
10
Sigurdsson, Haraldur
10
Thorsteinsson, Thorsteinn
7
Bodor, Nicholas
6
Konrádsdóttir, Fífa
6
Sigurjónsdóttir, Jóhanna
5
Brewster, ME
4
Masson, M
4
Olafsson, Jon
3
Pop, E
3
Brewster, Marcus
3
Haraldsson, Gunnsteinn
3
Hreinsdóttir, Dagný
2
Jarho, Pekka
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All Publications
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2009: Gisladottir Svanborg; Loftsson Thorsteinn; Stefansson Einar
Diffusion characteristics of vitreous humour and saline solution follow the Stokes Einstein equation.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2009;247(12):1677-84.
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2009: Jansook Phatsawee; Loftsson Thorsteinn
CDs as solubilizers: effects of excipients and competing drugs.
International journal of pharmaceutics 2009;379(1):32-40.
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2009: Konrádsdóttir Fífa; Loftsson Thorsteinn; Sigfússon Sigurdur Dadi
Fish skin as a model membrane: structure and characteristics.
The Journal of pharmacy and pharmacology 2009;61(1):121-4.
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2009: Konrádsdóttir Fífa; Ogmundsdóttir Helga; Sigurdsson Valgardur; Loftsson Thorsteinn
Drug targeting to the hair follicles: a cyclodextrin-based drug delivery.
AAPS PharmSciTech 2009;10(1):266-9.
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2008: Jansook Phatsawee; Loftsson Thorsteinn
gammaCD/HPgammaCD: synergistic solubilization.
International journal of pharmaceutics 2008;363(1-2):217-9.
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2008: Brewster Marcus E; Vandecruys Roger; Peeters Jef; Neeskens Peter; Verreck Geert; Loftsson Thorsteinn
Comparative interaction of 2-hydroxypropyl-beta-cyclodextrin and sulfobutylether-beta-cyclodextrin with itraconazole: phase-solubility behavior and stabilization of supersaturated drug solutions.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2008;34(2-3):94-103.
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2008: Loftsson Thorsteinn; Brewster Marcus E
Physicochemical properties of water and its effect on drug delivery. A commentary.
International journal of pharmaceutics 2008;354(1-2):248-54.
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2008: Loftsson T; Sigurdsson H H; Konrádsdóttir F; Gísladóttir S; Jansook P; Stefánsson E
Topical drug delivery to the posterior segment of the eye: anatomical and physiological considerations.
Die Pharmazie 2008;63(3):171-9.
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2008: Loftsson Thorsteinn; Vogensen Stine Byskov; Desbos Cyrielle; Jansook Phatsawee
Carvedilol: solubilization and cyclodextrin complexation: a technical note.
AAPS PharmSciTech 2008;9(2):425-30.
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2007: Iwai Junya; Ogawa Noriko; Nagase Hiromasa; Endo Tomohiro; Loftsson Thorsteinn; Ueda Haruhisa
Effects of various cyclodextrins on the stability of freeze-dried lactate dehydrogenase.
Journal of pharmaceutical sciences 2007;96(11):3140-3.
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2007: Loftsson Thorsteinn; Vogensen Stine Byskov; Brewster Marcus E; Konrádsdóttir Fífa
Effects of cyclodextrins on drug delivery through biological membranes.
Journal of pharmaceutical sciences 2007;96(10):2532-46.
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2007: Sigurdsson Hakon H; Konráethsdóttir Fífa; Loftsson Thorsteinn; Stefánsson Einar
Topical and systemic absorption in delivery of dexamethasone to the anterior and posterior segments of the eye.
Acta ophthalmologica Scandinavica 2007;85(6):598-602.
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2007: Brewster Marcus E; Noppe Marc; Peeters Jef; Loftsson Thorsteinn
Effect of the unstirred water layer on permeability enhancement by hydrophilic cyclodextrins.
International journal of pharmaceutics 2007;342(1-2):250-3.
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2007: Brewster Marcus E; Loftsson Thorsteinn
Cyclodextrins as pharmaceutical solubilizers.
Advanced drug delivery reviews 2007;59(7):645-66.
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2007: Tomren M A; Másson M; Loftsson T; Tønnesen H Hjorth
Studies on curcumin and curcuminoids XXXI. Symmetric and asymmetric curcuminoids: stability, activity and complexation with cyclodextrin.
International journal of pharmaceutics 2007;338(1-2):27-34.
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2007: Loftsson Thorsteinn; Hreinsdóttir Dagný; Stefánsson Einar
Cyclodextrin microparticles for drug delivery to the posterior segment of the eye: aqueous dexamethasone eye drops.
The Journal of pharmacy and pharmacology 2007;59(5):629-35.
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2007: Loftsson Thorsteinn; Duchêne Dominique
Cyclodextrins and their pharmaceutical applications.
International journal of pharmaceutics 2007;329(1-2):1-11.
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2006: Stefánsson Einar; Loftsson Thorsteinn
The Stokes-Einstein equation and the physiological effects of vitreous surgery.
Acta ophthalmologica Scandinavica 2006;84(6):718-9.
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2006: Loftsson Thorsteinn; Konrádsdóttir Fífa; Másson Már
Development and evaluation of an artificial membrane for determination of drug availability.
International journal of pharmaceutics 2006;326(1-2):60-8.
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2006: Sigurdsson Hakon H; Loftsson Thorsteinn; Lehr Claus-Michael
Assessment of mucoadhesion by a resonant mirror biosensor.
International journal of pharmaceutics 2006;325(1-2):75-81.
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2006: Hardarson Sveinn Hákon; Sigurdsson Hákon Hrafn; Níelsdóttir Gudrún Eva; Valgeirsson Jón; Loftsson Thorsteinn; Stefánsson Einar
Ocular powder: dry topical formulations of timolol are well tolerated in rabbits.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2006;22(5):340-6.
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2006: Dale Ola; Nilsen Turid; Loftsson Thorsteinn; Hjorth Tønnesen Hanne; Klepstad Pål; Kaasa Stein; Holand Trond; Djupesland Per G
Intranasal midazolam: a comparison of two delivery devices in human volunteers.
The Journal of pharmacy and pharmacology 2006;58(10):1311-8.
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2006: Másson M; Benediktsson T; Thorsteinsson T; Loftsson T
Investigation of soft long chain quaternary ammonium compounds as co-factors to enhance in vitro gene delivery.
Die Pharmazie 2006;61(6):564-6.
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2006: Saari K Matti; Nelimarkka Laura; Ahola Virpi; Loftsson Thorsteinn; Stefánsson Einar
Comparison of topical 0.7% dexamethasone-cyclodextrin with 0.1% dexamethasone sodium phosphate for postcataract inflammation.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2006;244(5):620-6.
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2006: Loftsson T; Konrádsdóttir F; Másson M
Influence of aqueous diffusion layer on passive drug diffusion from aqueous cyclodextrin solutions through biological membranes.
Die Pharmazie 2006;61(2):83-9.
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2006: Loftsson Thorsteinn; Hreinsdóttir Dagný
Determination of aqueous solubility by heating and equilibration: a technical note.
AAPS PharmSciTech 2006;7(1):E4.
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2005: Loftsson Thorsteinn; Hreinsdóttir Dagný; Másson Már
Evaluation of cyclodextrin solubilization of drugs.
International journal of pharmaceutics 2005;302(1-2):18-28.
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2005: Másson Már; Sigurdardóttir Birna Vigdís; Matthíasson Kristján; Loftsson Thorsteinn
Investigation of drug-cyclodextrin complexes by a phase-distribution method: some theoretical and practical considerations.
Chemical & pharmaceutical bulletin 2005;53(8):958-64.
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2005: Loftsson Thorsteinn; Thorsteinsson Thorsteinn; Másson Már
Hydrolysis kinetics and QSAR investigation of soft antimicrobial agents.
The Journal of pharmacy and pharmacology 2005;57(6):721-7.
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2005: Duan Matt S; Zhao Nelson; Ossurardóttir Ina B; Thorsteinsson Thorsteinn; Loftsson Thorsteinn
Cyclodextrin solubilization of the antibacterial agents triclosan and triclocarban: formation of aggregates and higher-order complexes.
International journal of pharmaceutics 2005;297(1-2):213-22.
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2005: Loftsson Thorsteinn; Jarho Pekka; Másson Már; Järvinen Tomi
Cyclodextrins in drug delivery.
Expert opinion on drug delivery 2005;2(2):335-51.
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2005: Sigurdsson Hakon H; Stefánsson Einar; Gudmundsdóttir Elínborg; Eysteinsson Thór; Thorsteinsdóttir Margrét; Loftsson Thorsteinn
Cyclodextrin formulation of dorzolamide and its distribution in the eye after topical administration.
Journal of controlled release : official journal of the Controlled Release Society 2005;102(1):255-62.
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2004: Loftsson T; Thorsteinsson T; Másson M
Marine lipids as building blocks for soft quaternary ammonium compounds and their antibacterial activity.
Die Pharmazie 2004;59(5):360-4.
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2004: Loftsson Thorsteinn; Másson Már; Brewster Marcus E
Self-association of cyclodextrins and cyclodextrin complexes.
Journal of pharmaceutical sciences 2004;93(5):1091-9.
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2004: Loftsson T; Sigurdsson H H; Másson M; Schipper N
Preparation of solid drug/cyclodextrin complexes of acidic and basic drugs.
Die Pharmazie 2004;59(1):25-9.
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2003: Thorsteinsson Thorsteinn; Másson Már; Kristinsson Karl G; Hjálmarsdóttir Martha A; Hilmarsson Hilmar; Loftsson Thorsteinn
Soft antimicrobial agents: synthesis and activity of labile environmentally friendly long chain quaternary ammonium compounds.
Journal of medicinal chemistry 2003;46(19):4173-81.
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2003: Loftsson Thorsteinn; Matthíasson Kristján; Másson Már
The effects of organic salts on the cyclodextrin solubilization of drugs.
International journal of pharmaceutics 2003;262(1-2):101-7.
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2003: Ribeiro Laura; Loftsson Thorsteinn; Ferreira Domingos; Veiga Francisco
Investigation and physicochemical characterization of vinpocetine-sulfobutyl ether beta-cyclodextrin binary and ternary complexes.
Chemical & pharmaceutical bulletin 2003;51(8):914-22.
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2003: Thorsteinsson T; Loftsson T; Masson M
Soft antibacterial agents.
Current medicinal chemistry 2003;10(13):1129-36.
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2003: Loftsson T; Gudmundsson J A; Arnadóttir R O; Fridriksdóttir H
Sublingual delivery of 17beta-estradiol from cyclodextrin containing tablets.
Die Pharmazie 2003;58(5):358-9.
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2003: Másson Már; Sigurjónsdóttir Jóhanna F; Jónsdóttir Sigrídur; Loftsson Thorsteinn
Examination of 19F-NMR as a tool for investigation of drug-cyclodextrin complexes.
Drug development and industrial pharmacy 2003;29(1):107-12.
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2002: Loftsson Thorsteinn; Magnúsdóttir Auethur; Másson Már; Sigurjónsdóttir Jóhanna F
Self-association and cyclodextrin solubilization of drugs.
Journal of pharmaceutical sciences 2002;91(11):2307-16.
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2002: Tønnesen Hanne Hjorth; Másson Már; Loftsson Thorsteinn
Studies of curcumin and curcuminoids. XXVII. Cyclodextrin complexation: solubility, chemical and photochemical stability.
International journal of pharmaceutics 2002;244(1-2):127-35.
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2002: Tsutsumi Keiko; Obata Yasuko; Nagai Tsuneji; Loftsson Thorsteinn; Takayama Kozo
Buccal absorption of ergotamine tartrate using the bioadhesive tablet system in guinea-pigs.
International journal of pharmaceutics 2002;238(1-2):161-70.
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2002: Thorsteinsson Thorsteinn; Másson Már; Jarvinen Tomi; Nevalainen Tapio; Loftsson Thorsteinn
Cycloserine fatty acid derivatives as prodrugs: synthesis, degradation and in vitro skin permeability.
Chemical & pharmaceutical bulletin 2002;50(4):554-7.
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2002: Loftsson Thorsteinn; Stefánsson Einar
Cyclodextrins in eye drop formulations: enhanced topical delivery of corticosteroids to the eye.
Acta ophthalmologica Scandinavica 2002;80(2):144-50.
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2002: Brewster M E; Loftsson T
The use of chemically modified cyclodextrins in the development of formulations for chemical delivery systems.
Die Pharmazie 2002;57(2):94-101.
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2002: Loftsson Thorsteinn; Másson Már; Sigurdsson Hákon H
Cyclodextrins and drug permeability through semi-permeable cellophane membranes.
International journal of pharmaceutics 2002;232(1-2):35-43.
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2001: Gudmundsdottir H; Sigurjonsdottir J F; Masson M; Fjalldal O; Stefansson E; Loftsson T
Intranasal administration of midazolam in a cyclodextrin based formulation: bioavailability and clinical evaluation in humans.
Die Pharmazie 2001;56(12):963-6.
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2001: Loftsson T; Leeves N; Sigurjónsdóttir J F; Sigurdsson H H; Másson M
Sustained drug delivery system based on a cationic polymer and an anionic drug/cyclodextrin complex.
Die Pharmazie 2001;56(9):746-7.
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2001: Loftsson T; Masson M
Cyclodextrins in topical drug formulations: theory and practice.
International journal of pharmaceutics 2001;225(1-2):15-30.
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2001: Loftsson T; Gudmundsdóttir H; Sigurjónsdóttir J F; Sigurdsson H H; Sigfússon S D; Másson M; Stefánsson E
Cyclodextrin solubilization of benzodiazepines: formulation of midazolam nasal spray.
International journal of pharmaceutics 2001;212(1):29-40.
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2000: Gudmundsdóttir E; Stefánsson E; Bjarnadóttir G; Sigurjónsdóttir J F; Gudmundsdóttir G; Masson M; Loftsson T
Methazolamide 1% in cyclodextrin solution lowers IOP in human ocular hypertension.
Investigative ophthalmology & visual science 2000;41(11):3552-4.
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2000: Thorsteinsson T; Masson M; Loftsson T
Dermal delivery of ETH-615, a zwitterionic drug.
Drug development and industrial pharmacy 2000;26(7):709-14.
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2000: Másson M; Thorsteinsson T; Sigurdsson T H; Loftsson T
Lipophilic metronidazole derivatives and their absorption through hairless mouse skin.
Die Pharmazie 2000;55(5):369-71.
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2000: Másson M; Loftsson T; Haraldsson G G
Marine lipids for prodrugs, soft compounds and other pharmaceutical applications.
Die Pharmazie 2000;55(3):172-7.
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1999: Loftsson T; Leeves N; Bjornsdottir B; Duffy L; Masson M
Effect of cyclodextrins and polymers on triclosan availability and substantivity in toothpastes in vivo.
Journal of pharmaceutical sciences 1999;88(12):1254-8.
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1999: Thorsteinsson T; Másson M; Loftsson T; Haraldsson G G; Stefánsson E
Diacyl glyceryl ester prodrugs for slow release in the skin: synthesis and in vitro degradation and absorption studies for naproxen derivatives.
Die Pharmazie 1999;54(11):831-6.
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1999: Sigurjónsdóttir J F; Loftsson T; Másson M
Influence of cyclodextrins on the stability of the peptide salmon calcitonin in aqueous solution.
International journal of pharmaceutics 1999;186(2):205-13.
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1999: Másson M; Loftsson T; Másson G; Stefánsson E
Cyclodextrins as permeation enhancers: some theoretical evaluations and in vitro testing.
Journal of controlled release : official journal of the Controlled Release Society 1999;59(1):107-18.
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1998: Loftsson T
Increasing the cyclodextrin complexation of drugs and drug biovailability through addition of water-soluble polymers.
Die Pharmazie 1998;53(11):733-40.
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1998: Savolainen J; Järvinen K; Taipale H; Jarho P; Loftsson T; Järvinen T
Co-administration of a water-soluble polymer increases the usefulness of cyclodextrins in solid oral dosage forms.
Pharmaceutical research 1998;15(11):1696-701.
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1998: Tsutsumi K; Obata Y; Takayama K; Loftsson T; Nagai T
Effect of cod-liver oil extract on the buccal permeation of ergotamine tartrate.
Drug development and industrial pharmacy 1998;24(8):757-62.
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1998: Holbrook W P; Kristmundsdóttir T; Loftsson T
Aqueous hydrocortisone mouthwash solution: clinical evaluation.
Acta odontologica Scandinavica 1998;56(3):157-60.
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1998: Loftsson T; Petersen D S
Cyclodextrin solubilization of ETH-615, a zwitterionic drug.
Drug development and industrial pharmacy 1998;24(4):365-70.
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1998: Loftsson T; Olafsson J H
Cyclodextrins: new drug delivery systems in dermatology.
International journal of dermatology 1998;37(4):241-6.
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1998: Loftsson T; Másson M; Sigurdsson H H; Magnússon P; Le Goffic F
Cyclodextrins as co-enhancers in dermal and transdermal drug delivery.
Die Pharmazie 1998;53(2):137-9.
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1997: Loftsson T; Gunnarsdóttir T; Magnúsdóttir L M; Frioriksdóttir H; Guomundsdóttir T K; Olafsson J H; Haraldsson G G; Guomundsson G; Hjaltason B
Effect of various marine lipids on transdermal drug delivery--in vitro evaluation.
Bollettino chimico farmaceutico 1997;136(10):640-5.
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1997: Loftsson T; Petersen D S; Le Goffic F; Olafsson J H
Unsaturated glycerol monoethers as novel skin penetration enhancers.
Die Pharmazie 1997;52(6):463-5.
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1996: Loftsson T; Brewster M E
Pharmaceutical applications of cyclodextrins. 1. Drug solubilization and stabilization.
Journal of pharmaceutical sciences 1996;85(10):1017-25.
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1996: Kristinsson J K; Fridriksdóttir H; Thórisdóttir S; Sigurdardóttir A M; Stefánsson E; Loftsson T
Dexamethasone-cyclodextrin-polymer co-complexes in aqueous eye drops. Aqueous humor pharmacokinetics in humans.
Investigative ophthalmology & visual science 1996;37(6):1199-203.
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1996: Fridriksdóttir H; Loftsson T; Gudmundsson J A; Bjarnason G J; Kjeld M; Thorsteinsson T
Design and in vivo testing of 17 beta-estradiol-HP beta CD sublingual tablets.
Die Pharmazie 1996;51(1):39-42.
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1995: Brewster M E; Anderson W R; Loftsson T; Huang M J; Bodor N; Pop E
Preparation, characterization, and anesthetic properties of 2-hydroxypropyl-beta-cyclodextrin complexes of pregnanolone and pregnenolone in rat and mouse.
Journal of pharmaceutical sciences 1995;84(10):1154-9.
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1995: Loftsson T; Gudmundsdóttir T K; Fridriksdóttir H; Sigurdardóttir A M; Thorkelsson J; Gudmundsson G; Hjaltason B
Fatty acids from cod-liver oil as skin penetration enhancers.
Die Pharmazie 1995;50(3):188-90.
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1994: Loftsson T; Frithriksdóttir H; Stefánsson E; Thórisdóttir S; Guthmundsson O; Sigthórsson T
Topically effective ocular hypotensive acetazolamide and ethoxyzolamide formulations in rabbits.
The Journal of pharmacy and pharmacology 1994;46(6):503-4.
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1993: Olafsson J H; Loftsson T; Fridriksdóttir H
Topical delivery of acetazolamide for psoriasis.
Acta dermato-venereologica 1993;73(6):467.
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1992: Bodor N; Loftsson T; Wu W M
Metabolism, distribution, and transdermal permeation of a soft corticosteroid, loteprednol etabonate.
Pharmaceutical research 1992;9(10):1275-8.
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1992: Loftsson T; Kristmundsdóttir T; Ingvarsdóttir K; Olafsdóttir B J; Baldvinsdóttir J
Preparation and physical evaluation of microcapsules of hydrophilic drug-cyclodextrin complexes.
Journal of microencapsulation 1992;9(3):375-82.
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1992: Raghavan K; Loftsson T; Brewster M E; Bodor N
Improved delivery through biological membranes. XLV. Synthesis, physical-chemical evaluation, and brain uptake studies of 2-chloroethyl nitrosourea delivery systems.
Pharmaceutical research 1992;9(6):743-9.
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1992: Loftsson T; Fridriksdóttir H
Stabilizing effect of tris(hydroxymethyl)aminomethane on N-nitrosoureas in aqueous solutions.
Journal of pharmaceutical sciences 1992;81(2):197-8.
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1992: Loftsson T; Baldvinsdóttir J
Degradation of tauromustine (TCNU) in aqueous solutions.
Acta pharmaceutica Nordica 1992;4(3):129-32.
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1991: Pop E; Loftsson T; Bodor N
Solubilization and stabilization of a benzylpenicillin chemical delivery system by 2-hydroxypropyl-beta-cyclodextrin.
Pharmaceutical research 1991;8(8):1044-9.
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1990: Pop E; Loftsson T; Bodor N
Novel central nervous system targeted semisynthetic penicillins.
Drug design and delivery 1990;5(3):221-37.
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1990: Bodor N; Loftsson T
The effect of phosphine oxides on transdermal delivery.
Acta pharmaceutica Nordica 1990;2(2):123-6.
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1989: Loftsson T; Gildersleeve N; Soliman R; Bodor N
Effect of oleic acid on diffusion of drugs through hairless mouse skin.
Acta pharmaceutica Nordica 1989;1(1):17-22.
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1988: Brewster M E; Estes K S; Loftsson T; Perchalski R; Derendorf H; Mullersman G; Bodor N
Improved delivery through biological membranes. XXXL: Solubilization and stabilization of an estradiol chemical delivery system by modified beta-cyclodextrins.
Journal of pharmaceutical sciences 1988;77(11):981-5.
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1987: Loftsson T; Gildersleeve N; Bodor N
The effect of vehicle additives on the transdermal delivery of nitroglycerin.
Pharmaceutical research 1987;4(5):436-7.
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