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TL Loftus

Research Profile

Chemicals & Drugs

Living Beings

HIV-1
HIV-2

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Cell Line

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Publications

TOP 3
A Casimiro-Garcia; Erik De Clercq; Christophe Pannecouque; M Witvrouw; TL Loftus; Jim A Turpin; Robert W Buckheit; Phillip E Fanwick; Mark Cushman
Synthesis and anti-HIV activity of cosalane analogues incorporating two dichlorodisalicylmethane pharmacophore fragments.
Guozhang Xu; TL Loftus; Heather Wargo; Jim A Turpin; Robert W Buckheit; Mark Cushman
Solid-phase synthesis of the alkenyldiarylmethane (ADAM) series of non-nucleoside HIV-1 reverse transcriptase inhibitors.
K C Santhosh; G C Paul; Erik De Clercq; Christophe Pannecouque; M Witvrouw; TL Loftus; Jim A Turpin; Robert W Buckheit; Mark Cushman
Correlation of anti-HIV activity with anion spacing in a series of cosalane analogues with extended polycarboxylate pharmacophores.

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All Publications

2001: A Casimiro-Garcia; Erik De Clercq; Christophe Pannecouque; M Witvrouw; TL Loftus; Jim A Turpin; Robert W Buckheit; Phillip E Fanwick; Mark Cushman
Synthesis and anti-HIV activity of cosalane analogues incorporating two dichlorodisalicylmethane pharmacophore fragments.
Bioorganic & medicinal chemistry 2001;9(11):2827-41.
2001: Guozhang Xu; TL Loftus; Heather Wargo; Jim A Turpin; Robert W Buckheit; Mark Cushman
Solid-phase synthesis of the alkenyldiarylmethane (ADAM) series of non-nucleoside HIV-1 reverse transcriptase inhibitors.
The Journal of organic chemistry 2001;66(18):5958-64.
2001: K C Santhosh; G C Paul; Erik De Clercq; Christophe Pannecouque; M Witvrouw; TL Loftus; Jim A Turpin; Robert W Buckheit; Mark Cushman
Correlation of anti-HIV activity with anion spacing in a series of cosalane analogues with extended polycarboxylate pharmacophores.
Journal of medicinal chemistry 2001;44(5):703-14.
2001: Robert W Buckheit; K Watson; V Fliakas-Boltz; Julie Russell; TL Loftus; MC Osterling; Jim A Turpin; Luke A Pallansch; E Lucile White; J W Lee; Sun Hwan Lee; J W Oh; H S Kwon; Sun G Chung; Eui-Hwan Cho
SJ-3366, a unique and highly potent nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 (HIV-1) that also inhibits HIV-2.
Antimicrobial agents and chemotherapy 2001;45(2):393-400.
2000: K C Santhosh; Erik De Clercq; Christophe Pannecouque; M Witvrouw; TL Loftus; Jim A Turpin; Robert W Buckheit; Mark Cushman
Anti-HIV activity of a series of cosalane amino acid conjugates.
Bioorganic & medicinal chemistry letters 2000;10(22):2505-8.
2000: G C Paul; Erik De Clercq; Christophe Pannecouque; M Witvrouw; TL Loftus; Jim A Turpin; Robert W Buckheit; Mark Cushman
Identification of optimal anion spacing for anti-HIV activity in a series of cosalane tetracarboxylates.
Bioorganic & medicinal chemistry letters 2000;10(18):2149-52.