John Logan

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Vascular Endothelium

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Byrne Guerard W; Stalboerger Paul G; Davila Eduardo; Heppelmann Carrie J; Gazi Mozammel H; McGregor Hugh C J; LaBreche Peter T; Davies William R; Rao Vinay P; Oi Keiji; Tazelaar Henry D; Logan John S; McGregor Christopher G A
Proteomic identification of non-Gal antibody targets after pig-to-primate cardiac xenotransplantation.
Byrne Guerard W; Davies William R; Oi Keiji; Rao Vinay P; Teotia Sumeet S; Ricci David; Tazelaar Henry D; Walker Randall C; Logan John S; McGregor Christopher G A
Increased immunosuppression, not anticoagulation, extends cardiac xenograft survival.
Gaca Jeffrey G; Appel James Z; Lukes Jeffrey G; Gonzalez-Stawinski Gonzalo V; Lesher Aaron; Palestrant Daniel; Logan John S; Love Stephanie D; Holzknecht Zoie E; Platt Jeffrey L; Parker William; Davis R Duane
Effect of an anti-C5a monoclonal antibody indicates a prominent role for anaphylatoxin in pulmonary xenograft dysfunction.

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All Publications

2008: Byrne Guerard W; Stalboerger Paul G; Davila Eduardo; Heppelmann Carrie J; Gazi Mozammel H; McGregor Hugh C J; LaBreche Peter T; Davies William R; Rao Vinay P; Oi Keiji; Tazelaar Henry D; Logan John S; McGregor Christopher G A
Proteomic identification of non-Gal antibody targets after pig-to-primate cardiac xenotransplantation.
Xenotransplantation 2008;15(4):268-76.
2006: Byrne Guerard W; Davies William R; Oi Keiji; Rao Vinay P; Teotia Sumeet S; Ricci David; Tazelaar Henry D; Walker Randall C; Logan John S; McGregor Christopher G A
Increased immunosuppression, not anticoagulation, extends cardiac xenograft survival.
Transplantation 2006;82(12):1787-91.
2006: Gaca Jeffrey G; Appel James Z; Lukes Jeffrey G; Gonzalez-Stawinski Gonzalo V; Lesher Aaron; Palestrant Daniel; Logan John S; Love Stephanie D; Holzknecht Zoie E; Platt Jeffrey L; Parker William; Davis R Duane
Effect of an anti-C5a monoclonal antibody indicates a prominent role for anaphylatoxin in pulmonary xenograft dysfunction.
Transplantation 2006;81(12):1686-94.
2006: Davila Eduardo; Byrne Guerard W; LaBreche Peter T; McGregor Hugh C J; Schwab Allison K; Davies William R; Rao Vinay P; Oi Keiji; Tazelaar Henry D; Logan John S; McGregor Christopher G A
T-cell responses during pig-to-primate xenotransplantation.
Xenotransplantation 2006;13(1):31-40.
2005: McGregor Christopher G A; Davies William R; Oi Keiji; Teotia Sumeet S; Schirmer Johannes M; Risdahl Jack M; Tazelaar Henry D; Kremers Walter K; Walker Randall C; Byrne Guerard W; Logan John S
Cardiac xenotransplantation: recent preclinical progress with 3-month median survival.
The Journal of thoracic and cardiovascular surgery 2005;130(3):844-51.
2005: Byrne Guerard W; Schirmer Johannes M; Fass David N; Teotia Sumeet S; Kremers Walter K; Xu Hui; Naziruddin Bashoo; Tazelaar Henry D; Logan John S; McGregor Christopher G A
Warfarin or low-molecular-weight heparin therapy does not prolong pig-to-primate cardiac xenograft function.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(5):1011-20.
2005: Teotia Sumeet S; Walker Randall C; Schirmer Johannes M; Tazelaar Henry D; Michaels Marian G; Risdahl Jack M; Byrne Guerard W; Logan John S; McGregor Christopher G A
Prevention, detection, and management of early bacterial and fungal infections in a preclinical cardiac xenotransplantation model that achieves prolonged survival.
Xenotransplantation 2005;12(2):127-33.
2004: McGregor Christopher G A; Teotia Sumeet S; Byrne Guerard W; Michaels Marian G; Risdahl Jack M; Schirmer Johannes M; Tazelaar Henry D; Walker Randall C; Logan John S
Cardiac xenotransplantation: progress toward the clinic.
Transplantation 2004;78(11):1569-75.
2004: Schirmer Johannes M; Fass David N; Byrne Guerard W; Tazelaar Henry D; Logan John S; McGregor Christopher G A
Effective antiplatelet therapy does not prolong transgenic pig to baboon cardiac xenograft survival.
Xenotransplantation 2004;11(5):436-43.
2003: Xu Hui; Sharma Ajay; Okabe Jeannine; Cui Cunqi; Huang Liping; Wei Yuan Yuan; Wan Hua; Lei Ying; Logan John S; Levy Marlon F; Byrne Guerard W
Serologic analysis of anti-porcine endogenous retroviruses immune responses in humans after ex vivo transgenic pig liver perfusion.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2003;49(4):407-16.
2003: Sharma Ajay; Naziruddin Bashoo; Cui Cunqi; Martin Michael J; Xu Hui; Wan Hua; Lei Ying; Harrison Caren; Yin Jessie; Okabe Jeannine; Mathews Christine; Stark Aileen; Adams Connie S; Houtz Jeffrey; Wiseman Barry S; Byrne Guerard W; Logan John S
Pig cells that lack the gene for alpha1-3 galactosyltransferase express low levels of the gal antigen.
Transplantation 2003;75(4):430-6.
2003: Xu Hui; Yin Dengping; Naziruddin Bashoo; Chen Libing; Stark Aileen; Wei Yuanyuan; Lei Ying; Shen JiKun; Logan John S; Byrne Guerard W; Chong Anita S-F
The in vitro and in vivo effects of anti-galactose antibodies on endothelial cell activation and xenograft rejection.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(3):1531-9.
2003: Karoor Sujatha; Molina Jeanette; Buchmann Cody R; Colton Clark; Logan John S; Henderson Lee W
Immunoaffinity removal of xenoreactive antibodies using modified dialysis or microfiltration membranes.
Biotechnology and bioengineering 2003;81(2):134-48.
2003: Martin Michael J; Yin Dengping; Adams Connie; Houtz Jeffrey; Shen Jikun; Chong Anita S; Sharma Ajay; Byrne Guerard W; Wiseman Barry S; Logan John S
Skin graft survival in genetically identical cloned pigs.
Cloning and stem cells 2003;5(2):117-21.
2002: Diamond Lisa E; Byrne Guerard W; Schwarz Alexander; Davis Thomas A; Adams David H; Logan John S
Analysis of the control of the anti-gal immune response in a non-human primate by galactose alpha1-3 galactose trisaccharide-polyethylene glycol conjugate.
Transplantation 2002;73(11):1780-7.
2002: Gonzalez-Stawinski Gonzalo V; Daggett Casey W; Lau Christine L; Karoor Sujatha; Love Stephanie D; Logan John S; Gaca Jeffrey G; Parker William; Davis Robert Duane
Non-anti-Gal alpha1-3Gal antibody mechanisms are sufficient to cause hyperacute lung dysfunction in pulmonary xenotransplantation.
Journal of the American College of Surgeons 2002;194(6):765-73.
2002: Xu Hui; Sharma Ajay; Lei Ying; Okabe Jeannine; Wan Hua; Chong Anita S-F; Logan John S; Byrne Guerard W
Development and characterization of anti-Gal B cell receptor transgenic Gal-/- mice.
Transplantation 2002;73(10):1549-57.
2002: Byrne Guerard W; Schwarz Alexander; Fesi Joanna R; Birch Patrick; Nepomich Anna; Bakaj Ivona; Velardo Margaret A; Jiang Cong; Manzi Adriana; Dintzis Howard; Diamond Lisa E; Logan John S
Evaluation of different alpha-Galactosyl glycoconjugates for use in xenotransplantation.
Bioconjugate chemistry 2002;13(3):571-81.
2002: Warnecke Gregor; Severson Sandra R; Ugurlu Mustafa M; Taner Cemal B; Logan John S; Diamond Lisa E; Miller Virginia M; McGregor Christopher G A
Endothelial function in pigs transgenic for human complement regulating factor.
Transplantation 2002;73(7):1060-7.
2002: Yin Dengping; Ma Lianli; Shen Jikun; Byrne Guerard W; Logan John S; Chong Anita S F
CTLA-41g in combination with anti-CD40L prolongs xenograft survival and inhibits anti-gal ab production in GT-Ko mice.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2002;2(1):41-7.
2001: Xu H; Sharma A; Chen L; Harrison C; Wei Y; Chong A S; Logan J S; Byrne G W;
The structure of anti-Gal immunoglobulin genes in naïve and stimulated Gal knockout mice.
Transplantation 2001;72(11):1817-25.
2001: Dean P G; Cohen A J; Dalla Valle H; Grande J P; Diamond L E; Byrne G W; Logan J S; McGregor C G; Stegall M D
The effect of anti-alphaGal antibody removal with immunoabsorption and splenectomy on CD46 transgenic kidney xenograft survival.
Transplantation proceedings 2001;33(1-2):721-2.
2001: Diamond L E; Quinn C M; Martin M J; Lawson J; Platt J L; Logan J S
A human CD46 transgenic pig model system for the study of discordant xenotransplantation.
Transplantation 2001;71(1):132-42.
2000: Lin S S; Hanaway M J; Gonzalez-Stawinski G V; Lau C L; Parker W; Davis R D; Byrne G W; Diamond L E; Logan J S; Platt J L
The role of anti-Galalpha1-3Gal antibodies in acute vascular rejection and accommodation of xenografts.
Transplantation 2000;70(12):1667-74.
2000: Chong A S; Ma L; Yin D; Shen J; Blinder L; XiuLong X; Williams J W; Byrne G; Diamond L E; Logan J S
Non-depleting anti-CD4, but not anti-CD8, antibody induces long-term survival of xenogeneic and allogeneic hearts in alpha1,3-galactosyltransferase knockout (GT-Ko) mice.
Xenotransplantation 2000;7(4):275-83.
2000: Logan J S
Prospects for xenotransplantation.
Current opinion in immunology 2000;12(5):563-8.
2000: Lau C L; Daggett W C; Yeatman M F; Chai P; Lin S S; Lodge A J; Chen E P; Diamond L E; Byrne G W; Logan J S; Parker W; Platt J L; Davis R D
The role of antibodies in dysfunction of pig-to-baboon pulmonary transplants.
The Journal of thoracic and cardiovascular surgery 2000;120(1):29-38.
2000: Schneider-Schaulies J; Martin M J; Logan J S; Firsching R; ter Meulen V; Diamond L E
CD46 transgene expression in pig peripheral blood mononuclear cells does not alter their susceptibility to measles virus or their capacity to downregulate endogenous and transgenic CD46.
The Journal of general virology 2000;81(Pt 6):1431-8.
1999: Chen R H; Naficy S; Logan J S; Diamond L E; Adams D H
Hearts from transgenic pigs constructed with CD59/DAF genomic clones demonstrate improved survival in primates.
Xenotransplantation 1999;6(3):194-200.
1999: Yeatman M; Daggett C W; Lau C L; Byrne G W; Logan J S; Platt J L; Davis R D
Human complement regulatory proteins protect swine lungs from xenogeneic injury.
The Annals of thoracic surgery 1999;67(3):769-75.
1999: Tone M; Diamond L E; Walsh L A; Tone Y; Thompson S A; Shanahan E M; Logan J S; Waldmann H
High level transcription of the complement regulatory protein CD59 requires an enhancer located in intron 1.
The Journal of biological chemistry 1999;274(2):710-6.
1998: Blixenkrone-Møller M; Bernard A; Bencsik A; Sixt N; Diamond L E; Logan J S; Wild T F
Role of CD46 in measles virus infection in CD46 transgenic mice.
Virology 1998;249(2):238-48.
1998: Yeatman M; Daggett C W; Parker W; Byrne G W; Logan J S; Platt J L; Davis R D
Complement-mediated pulmonary xenograft injury: studies in swine-to-primate orthotopic single lung transplant models.
Transplantation 1998;65(8):1084-93.
1998: Lin S S; Weidner B C; Byrne G W; Diamond L E; Lawson J H; Hoopes C W; Daniels L J; Daggett C W; Parker W; Harland R C; Davis R D; Bollinger R R; Logan J S; Platt J L
The role of antibodies in acute vascular rejection of pig-to-baboon cardiac transplants.
The Journal of clinical investigation 1998;101(8):1745-56.
1998: Kooyman D L; Byrne G W; Logan J S
Glycosyl phosphatidylinositol anchor.
Experimental nephrology 1998;6(2):148-51.
1997: McCurry K R; Parker W; Cotterell A H; Weidner B C; Lin S S; Daniels L J; Holzknecht Z E; Byrne G W; Diamond L E; Logan J S; Platt J L
Humoral responses to pig-to-baboon cardiac transplantation: implications for the pathogenesis and treatment of acute vascular rejection and for accommodation.
Human immunology 1997;58(2):91-105.
1997: Niewiesk S; Schneider-Schaulies J; Ohnimus H; Jassoy C; Schneider-Schaulies S; Diamond L; Logan J S; ter Meulen V
CD46 expression does not overcome the intracellular block of measles virus replication in transgenic rats.
Journal of virology 1997;71(10):7969-73.
1997: Lin S S; Kooyman D L; Daniels L J; Daggett C W; Parker W; Lawson J H; Hoopes C W; Gullotto C; Li L; Birch P; Davis R D; Diamond L E; Logan J S; Platt J L
The role of natural anti-Gal alpha 1-3Gal antibodies in hyperacute rejection of pig-to-baboon cardiac xenotransplants.
Transplant immunology 1997;5(3):212-8.
1997: Daggett C W; Yeatman M; Lodge A J; Chen E P; Van Trigt P; Byrne G W; Logan J S; Lawson J H; Platt J L; Davis R D
Swine lungs expressing human complement-regulatory proteins are protected against acute pulmonary dysfunction in a human plasma perfusion model.
The Journal of thoracic and cardiovascular surgery 1997;113(2):390-8.
1997: Byrne G W; McCurry K R; Martin M J; McClellan S M; Platt J L; Logan J S
Transgenic pigs expressing human CD59 and decay-accelerating factor produce an intrinsic barrier to complement-mediated damage.
Transplantation 1997;63(1):149-55.
1996: Sharma A; Okabe J; Birch P; McClellan S B; Martin M J; Platt J L; Logan J S
Reduction in the level of Gal(alpha1,3)Gal in transgenic mice and pigs by the expression of an alpha(1,2)fucosyltransferase.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(14):7190-5.
1996: McCurry K R; Diamond L E; Kooyman D L; Byrne G W; Martin M J; Logan J S; Platt J L
Human complement regulatory proteins expressed in transgenic swine protect swine xenografts from humoral injury.
Transplantation proceedings 1996;28(2):758.
1996: Oldham E R; Velardo M A; Platt J L; Logan J S; Diamond L
High-level tissue specific expression of human CD59, MCP, and DAF proteins from genomic clones in transgenic mice.
Transplantation proceedings 1996;28(2):693.
1996: Alvarado C G; Cotterell A H; Parker W; Logan J S; Platt J L
Variation in expression of biologically reactive xenoantigen does not correlate with expression of Gal alpha (1-3)Gal.
Transplantation proceedings 1996;28(2):555.
1996: Kooyman D L; McClellan S B; Parker W R; Avissar P L; Velardo M A; Nielsen D H; Platt J L; Logan J S
Identification and characterization of a peptide mimeotope of galactose alpha 1,3 galactose.
Transplantation proceedings 1996;28(2):554.
1996: Diamond L E; McCurry K R; Martin M J; McClellan S B; Oldham E R; Platt J L; Logan J S
Characterization of transgenic pigs expressing functionally active human CD59 on cardiac endothelium.
Transplantation 1996;61(8):1241-9.
1996: Kooyman D L; McClellan S B; Parker W; Avissar P L; Velardo M A; Platt J L; Logan J S
Identification and characterization of a galactosyl peptide mimetic. Implications for use in removing xenoreactive anti-A Gal antibodies.
Transplantation 1996;61(6):851-5.
1995: Diamond L E; McCurry K R; Oldham E R; Tone M; Waldmann H; Platt J L; Logan J S
Human CD59 expressed in transgenic mouse hearts inhibits the activation of complement.
Transplant immunology 1995;3(4):305-12.
1995: Byrne G W; McCurry K R; Kagan D; Quinn C; Martin M J; Platt J L; Logan J S
Protection of xenogeneic cardiac endothelium from human complement by expression of CD59 or DAF in transgenic mice.
Transplantation 1995;60(10):1149-56.
1995: Kooyman D L; Byrne G W; McClellan S; Nielsen D; Tone M; Waldmann H; Coffman T M; McCurry K R; Platt J L; Logan J S
In vivo transfer of GPI-linked complement restriction factors from erythrocytes to the endothelium.
Science (New York, N.Y.) 1995;269(5220):89-92.
1995: Alvarado C G; Cotterell A H; McCurry K R; Collins B H; Magee J C; Berthold J; Logan J S; Platt J L
Variation in the level of xenoantigen expression in porcine organs.
Transplantation 1995;59(11):1589-96.
1995: McCurry K R; Kooyman D L; Alvarado C G; Cotterell A H; Martin M J; Logan J S; Platt J L
Human complement regulatory proteins protect swine-to-primate cardiac xenografts from humoral injury.
Nature medicine 1995;1(5):423-7.
1995: McCurry K R; Kooyman D L; Diamond L E; Byrne G W; Logan J S; Platt J L
Transgenic expression of human complement regulatory proteins in mice results in diminished complement deposition during organ xenoperfusion.
Transplantation 1995;59(8):1177-82.
1995: Collins B H; Chari R S; Magee J C; Harland R C; Lindman B J; Logan J S; Bollinger R R; Meyers W C; Platt J L
Immunopathology of porcine livers perfused with blood of humans with fulminant hepatic failure.
Transplantation proceedings 1995;27(1):280-1.
1995: Cotterell A H; Alvarado C G; Logan J S; Platt J L
Variation in expression of porcine antigens recognized by human xenoreactive natural antibodies.
Transplantation proceedings 1995;27(1):278-9.
1995: McCurry K R; Kooyman D L; Diamond L E; Byrne G W; Martin M J; Logan J S; Platt J L
Human complement regulatory proteins in transgenic animals regulate complement activation in xenoperfused organs.
Transplantation proceedings 1995;27(1):317-8.
1994: Collins B H; Chari R S; Magee J C; Harland R C; Lindman B J; Logan J S; Bollinger R R; Meyers W C; Platt J L
Mechanisms of injury in porcine livers perfused with blood of patients with fulminant hepatic failure.
Transplantation 1994;58(11):1162-71.
1994: Harland R C; Logan J S; Kooyman D; Byrne G W; Platt J L
Ex vivo perfusion of mouse hearts expressing the human complement regulatory protein CD59.
Transplantation proceedings 1994;26(3):1245.
1994: Diamond L E; Oldham E R; Platt J L; Waldmann H; Tone M; Walsh L A; Logan J S
Cell- and tissue-specific expression of a human CD59 minigene in transgenic mice.
Transplantation proceedings 1994;26(3):1239.

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John Logan

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