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Jacob Lokich

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All Publications

2005: Jacob Lokich
Same-day pegfilgrastim and chemotherapy.
Cancer investigation 2005;23(7):573-6.
2004: Jacob Lokich
Tumor response and survival end points in clinical trials: a clinician's perspective.
American journal of clinical oncology 2004;27(5):494-6.
2004: Jacob Lokich
Capecitabine: fixed daily dose and continuous (noncyclic) dosing schedule.
Cancer investigation 2004;22(5):713-7.
2003: June Childress; Jacob Lokich
Cutaneous hand and foot toxicity associated with cancer chemotherapy.
American journal of clinical oncology 2003;26(5):435-6.
2003: Jacob Lokich; Norwood Anderson; Frank Coco
Alternating doublets: establishing the optimal multifractionated dosing schedule to administer docetaxel, cisplatin, gemcitabine, and vinorelbine in combination.
Cancer investigation 2003;21(6):830-6.
2002: Jacob Lokich
Multifractionated dosing for chemotherapy with flexible cytokine use: strategy for optimizing the therapeutic index.
American journal of clinical oncology 2002;25(1):101-2.
2002: Jacob Lokich
Diagnostic workup of neoplastic lesions in the cirrhotic liver: the case for minimizing invasive diagnostic studies.
Cancer investigation 2002;20(5-6):777-8.
1999: Jacob Lokich; H Sonneborn; N R Anderson; MM Bern; Frank Coco; E Dow; P Oliynyk
Combined paclitaxel, cisplatin, and etoposide for patients with previously untreated esophageal and gastroesophageal carcinomas.
Cancer 1999;85(11):2347-51.
1999: Jacob Lokich; Norwood Anderson; MM Bern; Frank Coco; E Dow
The multifractionated, twice-weekly dose schedule for a three-drug chemotherapy regimen: a phase I-II study of paclitaxel, cisplatin, and vinorelbine.
Cancer 1999;85(2):499-503.
1999: Norwood Anderson; Jacob Lokich; C Moore; MM Bern; Frank Coco
A dose-escalation phase II clinical trial of infusional mitomycin C for 7 days in patients with advanced measurable colorectal cancer refractory or resistant to 5-fluorouracil.
Cancer investigation 1999;17(8):586-93.
1999: Jacob Lokich
Multifractionated dosing for cancer chemotherapy: a novel schedule and a work in progress.
Cancer investigation 1999;17(7):551-4.
1999: Jacob Lokich
Single-dose granulocyte colony-stimulating factor concomitant with multifractionated dose chemotherapy: a strategy for maintaining dose intensity.
Cancer investigation 1999;17(7):547-50.
1998: Jacob Lokich
Infusional 5-FU: historical evolution, rationale, and clinical experience.
Oncology (Williston Park, N.Y.) 1998;12(10 Suppl 7):19-22.
1998: Jacob Lokich; H Levine; I Nasser
Malignancy-related hydrocephalus: clinical features and results of ventricular peritoneal shunt procedure in three patients.
American journal of clinical oncology 1998;21(4):366-8.
1998: Jacob Lokich; Norwood Anderson; C Moore; MM Bern; Frank Coco; H Sonneborn; E Dow; D Strong
Paclitaxel, cisplatin and etoposide combination chemotherapy: a comparison of dose intensity in two multifractionated dose schemas.
European journal of cancer (Oxford, England : 1990) 1998;34(5):664-7.
1998: Jacob Lokich; Norwood Anderson; MM Bern; Frank Coco; S Gotthardt; P Oliynyk; E Dow
Paclitaxel, cisplatin, etoposide combination chemotherapy: a multifractionated bolus dose schedule for non-small cell lung cancer.
European journal of cancer (Oxford, England : 1990) 1998;34(5):659-63.
1998: Jacob Lokich; C Moore; Norwood Anderson; MM Bern; Frank Coco; E Dow; T Zipoli
Phase I-II trial of 14 day infusional 6-mercaptopurine in advanced colorectal cancer.
European journal of cancer (Oxford, England : 1990) 1998;34(4):584-5.
1998: Jacob Lokich
Incurable breast cancer and long-term survival: anecdotes toward a new paradigm.
Cancer investigation 1998;16(4):295-6.
1998: Jacob Lokich; Norwood Anderson
Carboplatin versus cisplatin in solid tumors: an analysis of the literature.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1998;9(1):13-21.
1996: Jacob Lokich; C L Moore; N R Anderson
Comparison of costs for infusion versus bolus chemotherapy administration--Part two. Use of charges versus reimbursement for cost basis.
Cancer 1996;78(2):300-3.
1996: Jacob Lokich; C L Moore; N R Anderson
Comparison of costs for infusion versus bolus chemotherapy administration: analysis of five standard chemotherapy regimens in three common tumors--Part one. Model projections for cost based on charges.
Cancer 1996;78(2):294-9.
1996: Jacob Lokich; Norwood Anderson; C Moore; MM Bern; Frank Coco; E Dow; T Zipoli; L Gonzalves
Pilot study of ambulatory infusional delivery of a multidrug regimen: cisplatin, 5-fluorouracil and leucovorin (PFL) +/- etoposide.
The Journal of infusional chemotherapy 1996;6(1):43-6.
1996: Jacob Lokich; Norwood Anderson; C Moore; MM Bern; Frank Coco; E Dow
Pilot study of ambulatory infusional delivery of a multidrug regimen: ifosfamide, carboplatin and etoposide (ICE).
The Journal of infusional chemotherapy 1996;6(1):39-42.
1995: Jacob Lokich; Norwood Anderson; MM Bern; Frank Coco; E Dow; C Moore; T Zipoli; L Gonzalves
Multi-day fractionated administration schedule for paclitaxel.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1995;6(9):883-5.
1994: Jacob Lokich
Metastatic adamantinoma of bone to lung. A case report of the natural history and the use of chemotherapy and radiation therapy.
American journal of clinical oncology 1994;17(2):157-9.
1993: N R Anderson; Jacob Lokich; C Moore
The syndrome of 5-fluorouracil cardiotoxicity: an elusive cardiopathy.
Cancer 1993;72(7):2287-8.
1993: Jacob Lokich; T E Zipoli; N R Anderson; C Moore; L Gonzalves; MM Bern; Frank Coco
Pilot study of ambulatory infusional ifosfamide admixed with carboplatin.
Cancer 1993;71(6):2072-5.
1992: Jacob Lokich; Norwood Anderson; MM Bern; T Zipoli; L Gonsalves; C Moore
Etoposide plus carboplatin admixture. Phase I study of five- or seven-day continuous infusion.
American journal of clinical oncology 1992;15(4):314-8.
1991: Jacob Lokich; Norwood Anderson; MM Bern; Frank Coco; T Zipoli; C Moore; L Gonsalves
Dual modulation of 5-fluorouracil using leucovorin and hydroxyurea. A phase I trial.
Cancer 1991;68(4):744-6.
1991: Jacob Lokich; Norwood Anderson; MM Bern; T Zipli; L Gonsalves; C Moore
Infusional carboplatin. Phase I studies of 5-day and 14-day infusions.
Cancer 1991;68(1):68-71.
1991: Jacob Lokich; C Moore; Norwood Anderson; MM Bern
Infusion of floxuridine plus etoposide plus cisplatin in human malignancies.
European journal of cancer (Oxford, England : 1990) 1991;27(12):1593-6.
1989: Jacob Lokich; J Chaffey; W Neptune
Concomitant 5-fluorouracil infusion and high-dose radiation for stage III non-small cell lung cancer.
Cancer 1989;64(5):1021-5.
1989: Jacob Lokich; MM Bern; Norwood Anderson; S Wallach; C Moore; K Beauchamp; D Williams
Cyclophosphamide, methotrexate, and 5-fluorouracil in a three-drug admixture. Phase I trial of 14-day continuous ambulatory infusion.
Cancer 1989;63(5):822-4.
1989: Jacob Lokich; Norwood Anderson; MM Bern; S Wallach; C Moore; D Williams
Etoposide admixed with cisplatin. Phase I clinical investigation of 72-hour infusion.
Cancer 1989;63(5):818-21.
1989: Norwood Anderson; Jacob Lokich; MM Bern; S Wallach; C Moore; D Williams; V Umprayn
Combined 5-fluorouracil and floxuridine administered as a 14-day infusion. A phase I study.
Cancer 1989;63(5):825-7.
1989: Norwood Anderson; Jacob Lokich; MM Bern; S Wallach; C Moore; D Williams
A phase I clinical trial of combined fluoropyrimidines with leucovorin in a 14-day infusion. Demonstration of biochemical modulation.
Cancer 1989;63(2):233-7.
1989: Jacob Lokich; Merrill J Egorin; B E Cohen; MM Bern; T E Zipoli; C Moore
A phase I study of thiotepa administered by short-term and protracted continuous intravenous infusion.
Cancer 1989;63(1):46-50.
1988: Jacob Lokich; Norwood Anderson; MM Bern; S Wallach; C Moore; D Williams; V Umprain
Combined floxuridine and cisplatin in a fourteen day infusion. Phase I study.
Cancer 1988;62(11):2309-12.
1987: M M Bern; S R Wallach; C F Arkin; Jacob Lokich; M S Huberman; N R Anderson; J C Corkery; S D Paul; D F Phillips; H A Sonneborn
Etoposide in combination with cytarabine, doxorubicin, and 6-thioguanine for treatment of acute nonlymphoblastic leukemia in a protocol adjusted for age.
Cancer treatment reports 1987;71(2):201-3.
1986: Jacob Lokich; T Zipoli; R Green
Infusional cisplatin plus cyclophosphamide in advanced ovarian cancer.
Cancer 1986;58(11):2389-92.
1986: Jacob Lokich; T E Zipoli; C Moore; H Sonneborn; S Paul; R Greene
Doxorubicin/vinblastine and doxorubicin/cyclophosphamide combination chemotherapy by continuous infusion.
Cancer 1986;58(5):1020-3.
1986: Jacob Lokich; T Zipoli; R Greene; S Paul; H Sonnenborn; C Moore
Protracted low-dose cisplatin infusion in advanced colorectal cancer.
Cancer treatment reports 1986;70(4):523-4.
1986: M Huberman; Jacob Lokich; R Greene; S Paul; D Phillips; H Sonneborn; T Zipoli
Vinblastine plus cisplatin in advanced non-small cell lung cancer: lack of advantage for vinblastine infusion schedule.
Cancer treatment reports 1986;70(2):287-9.
1985: Jacob Lokich; D Phillips; R Green; S Paul; H Sonneborn; T E Zipoli; G Curt
5-Fluorouracil and methotrexate administered simultaneously as a continuous infusion. A phase I study.
Cancer 1985;56(10):2395-8.
1985: Jacob Lokich; G Curt
A phase I and pharmacology study of continuous-infusion low-dose methotrexate administration.
Cancer 1985;56(10):2391-4.
1985: H Matelski; R Greene; M Huberman; Jacob Lokich; T Zipoli
Randomized trial of estrogen vs. tamoxifen therapy for advanced breast cancer.
American journal of clinical oncology 1985;8(2):128-33.
1985: Jacob Lokich; T E Zipoli; H Sonneborn; S Paul; D Philips
Streptozotocin for metastatic malignant melanoma.
American journal of clinical oncology 1985;8(1):45-6.
1984: H W Matelski; Jacob Lokich; M S Huberman; T E Zipoli; S Paul; H Sonneborn; D Philips
Adriamycin, cyclophosphamide, and etoposide (VP-16-213) in extensive-stage small cell lung cancer.
American journal of clinical oncology 1984;7(6):729-32.
1984: Jacob Lokich; T E Zipoli; J Perri; A Bothe
Protracted vinblastine infusion. Phase I-II study in malignant melanoma and other tumors.
American journal of clinical oncology 1984;7(5):551-3.
1984: Jacob Lokich; T E Zipoli
Phase-I study of protracted infusion of cisplatin.
Cancer drug delivery 1984;1(3):247-50.
1983: Jacob Lokich; H Sonneborn; S Paul; T Zipoli
Phase I study of continuous venous infusion of floxuridine (5-FUDR) chemotherapy.
Cancer treatment reports 1983;67(9):791-3.
1983: Jacob Lokich; J Perri; A Bothe; T Zipoli; D Philips; H Sonneborn; S Paul; R Green
Cancer chemotherapy via ambulatory infusion pump.
American journal of clinical oncology 1983;6(3):355-63.
1983: Jacob Lokich; N Fine; J Perri; A Bothe
Protracted ambulatory venous infusion of 5-fluorouracil.
American journal of clinical oncology 1983;6(1):103-7.
1983: Jacob Lokich; A Bothe; T Zipoli; R Green; H Sonneborn; S Paul; D Philips
Constant infusion schedule for adriamycin: a phase I-II clinical trial of a 30-day schedule by ambulatory pump delivery system.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1983;1(1):24-8.
1982: Jacob Lokich; A Bothe; N Fine; J Perri
The delivery of cancer chemotherapy by constant venous infusion. Ambulatory management of venous access and portable pump.
Cancer 1982;50(12):2731-5.
1982: Jacob Lokich; J Perri; N Fine; A Bothe; T Nelson; R Greene; T Zipoli
Mitomycin C: phase I study of a constant infusion ambulatory treatment schedule.
American journal of clinical oncology 1982;5(4):443-7.
1981: Jacob Lokich; T Kinsella; J Perri; A Malcolm; M Clouse
Concomitant hepatic radiation and intraarterial fluorinated pyrimidine therapy: correlation of liver scan, liver function tests, and plasma CEA with tumor response.
Cancer 1981;48(12):2569-74.
1981: Jacob Lokich; A Bothe; N Fine; J Perri
Phase I study of protracted venous infusion of 5-fluorouracil.
Cancer 1981;48(12):2565-8.
1981: C G Moertel; S Frytak; Richard G Hahn; M J O'Connell; R J Reitemeier; J Rubin; A J Schutt; L H Weiland; D S Childs; M A Holbrook; P T Lavin; E Livstone; H Spiro; A Knowlton; M Kalser; Jamie S Barkin; H Lessner; Richard S. Kaplan; K Ramming; H O Douglas; P Thomas; H Nave; J Bateman; Jacob Lokich; J Brooks; J Chaffey; J M Corson; N Zamcheck; J W Novak
Therapy of locally unresectable pancreatic carcinoma: a randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads + 5-fluorouracil), and high dose radiation + 5-fluorouracil: The Gastrointestinal Tumor Study Group.
Cancer 1981;48(8):1705-10.