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Clare London

Research Profile

Chemicals & Drugs

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Patch-Clamp Techniques

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Electrophysiology

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Scott B Hoyt; Nina Jochnowitz; Gregory J Kaczorowski; Bindhu V Karanam; Xiaohua Li; Clare London; Kathryn A Lyons; Erin McGowan; Birgit T Priest; McHardy M Smith; Brande S Thomas-Fowlkes; Vivien A Warren; Catherine Abbadie; John P Felix; Maria L Garcia; Joseph L Duffy
A novel benzazepinone sodium channel blocker with oral efficacy in a rat model of neuropathic pain.
Andrew M Swensen; Vivien A Warren; David Parker; Kevin S Ratliff; McHardy Smith; Terrance P Snutch; Stephen P Arneric; Randal M Bugianesi; Ge Dai; Joseph L Duffy; Cyrus Eduljee; Rodolfo J Haedo; James Herrington; Scott B Hoyt; Gregory J Kaczorowski; Clare London; Owen B McManus
Characterization of the substituted N-triazole oxindole TROX-1, a small-molecule, state-dependent inhibitor of Ca(V)2 calcium channels.
Catherine Abbadie; Owen B McManus; Shu-Yu Sun; Randal M Bugianesi; Ge Dai; Rodolfo J Haedo; James B Herrington; Gregory J Kaczorowski; McHardy Smith; Andrew M Swensen; Vivien A Warren; Brande Williams; Stephen P Arneric; Cyrus Eduljee; Terrance P Snutch; Elizabeth W Tringham; Nina Jochnowitz; Annie Liang; D Euan MacIntyre; Erin McGowan; Shruti Mistry; Valerie V White; Scott B Hoyt; Clare London; Kathryn A Lyons; Patricia B Bunting; Sylvia Volksdorf; Joseph L Duffy
Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker.

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All Publications

2013: Scott B Hoyt; Nina Jochnowitz; Gregory J Kaczorowski; Bindhu V Karanam; Xiaohua Li; Clare London; Kathryn A Lyons; Erin McGowan; Birgit T Priest; McHardy M Smith; Brande S Thomas-Fowlkes; Vivien A Warren; Catherine Abbadie; John P Felix; Maria L Garcia; Joseph L Duffy
A novel benzazepinone sodium channel blocker with oral efficacy in a rat model of neuropathic pain.
Bioorganic & medicinal chemistry letters 2013;23(12):3640-5.
2012: Andrew M Swensen; Vivien A Warren; David Parker; Kevin S Ratliff; McHardy Smith; Terrance P Snutch; Stephen P Arneric; Randal M Bugianesi; Ge Dai; Joseph L Duffy; Cyrus Eduljee; Rodolfo J Haedo; James Herrington; Scott B Hoyt; Gregory J Kaczorowski; Clare London; Owen B McManus
Characterization of the substituted N-triazole oxindole TROX-1, a small-molecule, state-dependent inhibitor of Ca(V)2 calcium channels.
Molecular pharmacology 2012;81(3):488-97.
2010: Catherine Abbadie; Owen B McManus; Shu-Yu Sun; Randal M Bugianesi; Ge Dai; Rodolfo J Haedo; James B Herrington; Gregory J Kaczorowski; McHardy Smith; Andrew M Swensen; Vivien A Warren; Brande Williams; Stephen P Arneric; Cyrus Eduljee; Terrance P Snutch; Elizabeth W Tringham; Nina Jochnowitz; Annie Liang; D Euan MacIntyre; Erin McGowan; Shruti Mistry; Valerie V White; Scott B Hoyt; Clare London; Kathryn A Lyons; Patricia B Bunting; Sylvia Volksdorf; Joseph L Duffy
Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker.
The Journal of pharmacology and experimental therapeutics 2010;334(2):545-55.
2008: Scott B Hoyt; Clare London; Matthew J Wyvratt; Michael H Fisher; Doreen E Cashen; John P Felix; Maria L Garcia; Xiaohua Li; Kathryn A Lyons; D Euan MacIntyre; William J Martin; Birgit T Priest; McHardy Smith; Vivien A Warren; Brande S Williams; Gregory J Kaczorowski; William H Parsons
3-Amino-1,5-benzodiazepinones: potent, state-dependent sodium channel blockers with anti-epileptic activity.
Bioorganic & medicinal chemistry letters 2008;18(6):1963-6.
2008: Clare London; Scott B Hoyt; William H Parsons; Brande S Williams; Vivien A Warren; Richard A Tschirret-Guth; McHardy Smith; Birgit T Priest; Erin McGowan; William J Martin; Kathryn A Lyons; Xiaohua Li; Bindhu V Karanam; Nina Jochnowitz; Maria L Garcia; John P Felix; Brian Dean; Catherine Abbadie; Gregory J Kaczorowski; Joseph L Duffy
Imidazopyridines: a novel class of hNav1.7 channel blockers.
Bioorganic & medicinal chemistry letters 2008;18(5):1696-701.
2007: Brande S Williams; John P Felix; Birgit T Priest; Richard Brochu; Kefei Dai; Scott B Hoyt; Clare London; Yui S Tang; Joseph L Duffy; William H Parsons; Gregory J Kaczorowski; Maria L Garcia
Characterization of a new class of potent inhibitors of the voltage-gated sodium channel Nav1.7.
Biochemistry 2007;46(50):14693-703.
2007: Scott B Hoyt; Clare London; Hyun O Ok; Edward Gonzalez; Joseph L Duffy; Catherine Abbadie; Brian Dean; John P Felix; Maria L Garcia; Nina Jochnowitz; Bindhu V Karanam; Xiaohua Li; Kathryn A Lyons; Erin McGowan; D Euan MacIntyre; William J Martin; Birgit T Priest; McHardy Smith; Richard A Tschirret-Guth; Vivien A Warren; Brande S Williams; Gregory J Kaczorowski; William H Parsons
Benzazepinone Nav1.7 blockers: potential treatments for neuropathic pain.
Bioorganic & medicinal chemistry letters 2007;17(22):6172-7.
2007: Scott B Hoyt; Clare London; David J. Gorin; Matthew J Wyvratt; Michael H Fisher; Catherine Abbadie; John P Felix; Maria L Garcia; Xiaohua Li; Kathryn A Lyons; Erin McGowan; D Euan MacIntyre; William J Martin; Birgit T Priest; Amy Ritter; McHardy Smith; Vivien A Warren; Brande S Williams; Gregory J Kaczorowski; William H Parsons
Discovery of a novel class of benzazepinone Na(v)1.7 blockers: potential treatments for neuropathic pain.
Bioorganic & medicinal chemistry letters 2007;17(16):4630-4.