FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Richard Longnecker

Research Profile

Living Beings

Chemicals & Drugs

Anatomy

Physiology

Phenomena

Co-author Network

Publications

TOP 3
Jia Chen; Theodore S Jardetzky; Richard Longnecker
The large groove found in the gH/gL structure is an important functional domain for Epstein-Barr virus fusion.
Qing Fan; Kevin P Bohannon; Richard Longnecker
Drosophila Schneider 2 (S2) cells: a novel tool for studying HSV-induced membrane fusion.
Cynthia L Rowe; Jia Chen; Sarah A Connolly; Theodore S Jardetzky; Richard Longnecker
A soluble form of Epstein-Barr virus gH/gL inhibits EBV-induced membrane fusion and does not function in fusion.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Richard Longnecker (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Jia Chen; Theodore S Jardetzky; Richard Longnecker
The large groove found in the gH/gL structure is an important functional domain for Epstein-Barr virus fusion.
Journal of virology 2013;87(7):3620-7.
2013: Qing Fan; Kevin P Bohannon; Richard Longnecker
Drosophila Schneider 2 (S2) cells: a novel tool for studying HSV-induced membrane fusion.
Virology 2013;437(2):100-9.
2013: Cynthia L Rowe; Jia Chen; Sarah A Connolly; Theodore S Jardetzky; Richard Longnecker
A soluble form of Epstein-Barr virus gH/gL inhibits EBV-induced membrane fusion and does not function in fusion.
Virology 2013;436(1):118-26.
2013: Nicholas J Garcia; Jia Chen; Richard Longnecker
Modulation of Epstein-Barr virus glycoprotein B (gB) fusion activity by the gB cytoplasmic tail domain.
mBio 2013;4(1):e00571-12.
2013: Anna Zago; Patricia G Spear; Sarah A Connolly; Richard Longnecker
The fusion loops and membrane proximal region of Epstein-Barr virus glycoprotein B (gB) can function in the context of herpes simplex virus 1 gB when substituted individually but not in combination.
Virus research 2013;171(1):227-30.
2012: Andrew H Karaba; Sarah J Kopp; Richard Longnecker
Herpesvirus entry mediator is a serotype specific determinant of pathogenesis in ocular herpes.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(50):20649-54.
2012: Ann Hye-Ryong Shim; Richard Longnecker; Rhoda Ahn Chang; Xiaoyan Chen; Xiaolin He
Multipronged attenuation of macrophage-colony stimulating factor signaling by Epstein-Barr virus BARF1.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(32):12962-7.
2012: Qing Fan; Richard Longnecker
Is nectin-1 the "master" receptor for deadly herpes B virus infection?
Virulence 2012;3(4):405.
2012: Jamie L Dargart; Kamonwan Fish; Leo I Gordon; Richard Longnecker; Osman Cen
Dasatinib therapy results in decreased B cell proliferation, splenomegaly, and tumor growth in a murine model of lymphoma expressing Myc and Epstein-Barr virus LMP2A.
Antiviral research 2012;95(1):49-56.
2012: Sarah A Connolly; Richard Longnecker
Residues within the C-terminal arm of the herpes simplex virus 1 glycoprotein B ectodomain contribute to its refolding during the fusion step of virus entry.
Journal of virology 2012;86(12):6386-93.
2012: Rhoda A Chang; Stephen D Miller; Richard Longnecker
Epstein-Barr virus latent membrane protein 2A exacerbates experimental autoimmune encephalomyelitis and enhances antigen presentation function.
Scientific reports 2012;2():353.
2012: Alexandra C Vrazo; Nancy Raab-Traub; Maria Chauchard; Richard Longnecker
Epstein-Barr virus LMP2A reduces hyperactivation induced by LMP1 to restore normal B cell phenotype in transgenic mice.
PLoS pathogens 2012;8(4):e1002662.
2011: Andrew H Karaba; Sarah J Kopp; Richard Longnecker
Herpesvirus entry mediator and nectin-1 mediate herpes simplex virus 1 infection of the murine cornea.
Journal of virology 2011;85(19):10041-7.
2011: Cynthia L Rowe; Hisae Matsuura; Theodore S Jardetzky; Richard Longnecker
Investigation of the function of the putative self-association site of Epstein-Barr virus (EBV) glycoprotein 42 (gp42).
Virology 2011;415(2):122-31.
2011: Sarah A Connolly; Julia O Jackson; Theodore S Jardetzky; Richard Longnecker
Fusing structure and function: a structural view of the herpesvirus entry machinery.
Nature reviews. Microbiology 2011;9(5):369-81.
2011: Jasmina Smajlovic (Omerovic); Jessica J Reimer; Theodore S Jardetzky; Richard Longnecker
Mapping regions of Epstein-Barr virus (EBV) glycoprotein B (gB) important for fusion function with gH/gL.
Virology 2011;413(1):26-38.
2011: Osman Cen; Richard Longnecker
Rapamycin reverses splenomegaly and inhibits tumor development in a transgenic model of Epstein-Barr virus-related Burkitt's lymphoma.
Molecular cancer therapeutics 2011;10(4):679-86.
2010: Julia O Jackson; Richard Longnecker
Reevaluating herpes simplex virus hemifusion.
Journal of virology 2010;84(22):11814-21.
2010: Qing Fan; Richard Longnecker
The Ig-like v-type domain of paired Ig-like type 2 receptor alpha is critical for herpes simplex virus type 1-mediated membrane fusion.
Journal of virology 2010;84(17):8664-72.
2010: Michelle Swanson-Mungerson; Rebecca Bultema; Richard Longnecker
Epstein-Barr virus LMP2A imposes sensitivity to apoptosis.
The Journal of general virology 2010;91(Pt 9):2197-202.
2010: Pamela Shaw; Austin N Kirschner; Theodore S Jardetzky; Richard Longnecker
Characteristics of Epstein-Barr virus envelope protein gp42.
Virus genes 2010;40(3):307-19.
2010: Kathryn T Bieging; Michelle Swanson-Mungerson; Alexandra C Amick; Richard Longnecker
Epstein-Barr virus in Burkitt's lymphoma: a role for latent membrane protein 2A.
Cell cycle (Georgetown, Tex.) 2010;9(5):901-8.
2010: Julia O Jackson; Erick Lin; Patricia G Spear; Richard Longnecker
Insertion mutations in herpes simplex virus 1 glycoprotein H reduce cell surface expression, slow the rate of cell fusion, or abrogate functions in cell fusion and viral entry.
Journal of virology 2010;84(4):2038-46.
2009: Kathryn T Bieging; Alexandra C Amick; Richard Longnecker
Epstein-Barr virus LMP2A bypasses p53 inactivation in a MYC model of lymphomagenesis.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(42):17945-50.
2009: Jasmina Smajlovic (Omerovic); Jasmina Smajlović; Theodore S Jardetzky; Richard Longnecker
Functional analysis of glycoprotein L (gL) from rhesus lymphocryptovirus in Epstein-Barr virus-mediated cell fusion indicates a direct role of gL in gB-induced membrane fusion.
Journal of virology 2009;83(15):7678-89.
2009: Jessica Sorem; Theodore S Jardetzky; Richard Longnecker
Cleavage and secretion of Epstein-Barr virus glycoprotein 42 promote membrane fusion with B lymphocytes.
Journal of virology 2009;83(13):6664-72.
2009: R Bultema; Richard Longnecker; Michelle Swanson-Mungerson
Epstein-Barr virus LMP2A accelerates MYC-induced lymphomagenesis.
Oncogene 2009;28(11):1471-6.
2009: Jessica Sorem; Richard Longnecker
Cleavage of Epstein-Barr virus glycoprotein B is required for full function in cell-cell fusion with both epithelial and B cells.
The Journal of general virology 2009;90(Pt 3):591-5.
2009: Masato Ikeda; Richard Longnecker
The c-Cbl proto-oncoprotein downregulates EBV LMP2A signaling.
Virology 2009;385(1):183-91.
2009: Marija Backovic; Richard Longnecker; Theodore S Jardetzky
Structure of a trimeric variant of the Epstein-Barr virus glycoprotein B.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(8):2880-5.
2009: Austin N Kirschner; Jessica Sorem; Richard Longnecker; Theodore S Jardetzky
Structure of Epstein-Barr virus glycoprotein 42 suggests a mechanism for triggering receptor-activated virus entry.
Structure (London, England : 1993) 2009;17(2):223-33.
2009: Jessica J Reimer; Marija Backovic; Charuhas G Deshpande; Theodore S Jardetzky; Richard Longnecker
Analysis of Epstein-Barr virus glycoprotein B functional domains via linker insertion mutagenesis.
Journal of virology 2009;83(2):734-47.
2009: Leah J Anderson; Richard Longnecker
Epstein-Barr virus latent membrane protein 2A exploits Notch1 to alter B-cell identity in vivo.
Blood 2009;113(1):108-16.
2008: Mark Rovedo; Richard Longnecker
Epstein-Barr virus latent membrane protein 2A preferentially signals through the Src family kinase Lyn.
Journal of virology 2008;82(17):8520-8.
2008: Leah J Anderson; Richard Longnecker
EBV LMP2A provides a surrogate pre-B cell receptor signal through constitutive activation of the ERK/MAPK pathway.
The Journal of general virology 2008;89(Pt 7):1563-8.
2008: Leah J Anderson; Richard Longnecker
An auto-regulatory loop for EBV LMP2A involves activation of Notch.
Virology 2008;371(2):257-66.
2007: Marija Backovic; George P Leser; Robert A Lamb; Richard Longnecker; Theodore S Jardetzky
Characterization of EBV gB indicates properties of both class I and class II viral fusion proteins.
Virology 2007;368(1):102-13.
2007: Makoto Fukuda; Richard Longnecker
Epstein-Barr virus latent membrane protein 2A mediates transformation through constitutive activation of the Ras/PI3-K/Akt Pathway.
Journal of virology 2007;81(17):9299-306.
2007: Austin N Kirschner; Amanda S Lowrey; Richard Longnecker; Theodore S Jardetzky
Binding-site interactions between Epstein-Barr virus fusion proteins gp42 and gH/gL reveal a peptide that inhibits both epithelial and B-cell membrane fusion.
Journal of virology 2007;81(17):9216-29.
2007: Marija Backovic; Theodore S Jardetzky; Richard Longnecker
Hydrophobic residues that form putative fusion loops of Epstein-Barr virus glycoprotein B are critical for fusion activity.
Journal of virology 2007;81(17):9596-600.
2007: Jasmina Omerović; Richard Longnecker
Functional homology of gHs and gLs from EBV-related gamma-herpesviruses for EBV-induced membrane fusion.
Virology 2007;365(1):157-65.
2007: Michelle Swanson-Mungerson; Richard Longnecker
Epstein-Barr virus latent membrane protein 2A and autoimmunity.
Trends in immunology 2007;28(5):213-8.
2007: Masato Ikeda; Richard Longnecker
Cholesterol is critical for Epstein-Barr virus latent membrane protein 2A trafficking and protein stability.
Virology 2007;360(2):461-8.
2007: Mark Rovedo; Richard Longnecker
Epstein-barr virus latent membrane protein 2B (LMP2B) modulates LMP2A activity.
Journal of virology 2007;81(1):84-94.
2006: Austin N Kirschner; Jasmina Smajlovic (Omerovic); Boris Popov; Richard Longnecker; Theodore S Jardetzky
Soluble Epstein-Barr virus glycoproteins gH, gL, and gp42 form a 1:1:1 stable complex that acts like soluble gp42 in B-cell fusion but not in epithelial cell fusion.
Journal of virology 2006;80(19):9444-54.
2006: Michelle Swanson-Mungerson; Rebecca Bultema; Richard Longnecker
Epstein-Barr virus LMP2A enhances B-cell responses in vivo and in vitro.
Journal of virology 2006;80(14):6764-70.
2005: Jasmina Omerović; Lori Lev; Richard Longnecker
The amino terminus of Epstein-Barr virus glycoprotein gH is important for fusion with epithelial and B cells.
Journal of virology 2005;79(19):12408-15.
2005: Makoto Fukuda; Richard Longnecker
Epstein-Barr virus (EBV) latent membrane protein 2A regulates B-cell receptor-induced apoptosis and EBV reactivation through tyrosine phosphorylation.
Journal of virology 2005;79(13):8655-60.
2005: Michelle Swanson-Mungerson; Robert G Caldwell; Rebecca Bultema; Richard Longnecker
Epstein-Barr virus LMP2A alters in vivo and in vitro models of B-cell anergy, but not deletion, in response to autoantigen.
Journal of virology 2005;79(12):7355-62.
2005: Mihaela Stefan; Toni Portis; Richard Longnecker; Robert D Nicholls
A nonimprinted Prader-Willi Syndrome (PWS)-region gene regulates a different chromosomal domain in trans but the imprinted pws loci do not alter genome-wide mRNA levels.
Genomics 2005;85(5):630-40.
2005: Mihaela Stefan; Kathryn C Claiborn; Edyta Stasiek; Jing-Hua Chai; Tohru Ohta; Richard Longnecker; John M Greally; Robert D Nicholls
Genetic mapping of putative Chrna7 and Luzp2 neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes.
BMC genomics 2005;6():157.
2005: Masato Ikeda; Richard Longnecker
Pre-B-cell colony formation assay.
Methods in molecular biology (Clifton, N.J.) 2005;292():279-84.
2005: Marisa P McShane; Richard Longnecker
Analysis of fusion using a virus-free cell fusion assay.
Methods in molecular biology (Clifton, N.J.) 2005;292():187-96.
2004: Marisa P McShane; Richard Longnecker
Cell-surface expression of a mutated Epstein-Barr virus glycoprotein B allows fusion independent of other viral proteins.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(50):17474-9.
2004: Toni Portis; Richard Longnecker
Epstein-Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Ras/PI3K/Akt pathway.
Oncogene 2004;23(53):8619-28.
2004: Rebecca B Katzman; Richard Longnecker
LMP2A does not require palmitoylation to localize to buoyant complexes or for function.
Journal of virology 2004;78(20):10878-87.
2004: Toni Portis; Masato Ikeda; Richard Longnecker
Epstein-Barr virus LMP2A: regulating cellular ubiquitination processes for maintenance of viral latency?
Trends in immunology 2004;25(8):422-6.
2004: Amanda L Silva; Jasmina Smajlovic (Omerovic); Theodore S Jardetzky; Richard Longnecker
Mutational analyses of Epstein-Barr virus glycoprotein 42 reveal functional domains not involved in receptor binding but required for membrane fusion.
Journal of virology 2004;78(11):5946-56.
2004: Akiko Ikeda; Mark Merchant; Lori Lev; Richard Longnecker; Masato Ikeda
Latent membrane protein 2A, a viral B cell receptor homologue, induces CD5+ B-1 cell development.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(9):5329-37.
2004: Toni Portis; Richard Longnecker
Epstein-Barr virus (EBV) LMP2A alters normal transcriptional regulation following B-cell receptor activation.
Virology 2004;318(2):524-33.
2003: Toni Portis; Patricia Dyck; Richard Longnecker
Epstein-Barr Virus (EBV) LMP2A induces alterations in gene transcription similar to those observed in Reed-Sternberg cells of Hodgkin lymphoma.
Blood 2003;102(12):4166-78.
2003: Rebecca B Katzman; Richard Longnecker
Cholesterol-dependent infection of Burkitt's lymphoma cell lines by Epstein-Barr virus.
The Journal of general virology 2003;84(Pt 11):2987-92.
2003: Peter Speck; David F Callen; Richard Longnecker
Absence of the Epstein-Barr virus genome in breast cancer-derived cell lines.
Journal of the National Cancer Institute 2003;95(16):1253-4; author reply 1254-5.
2003: Michelle Swanson-Mungerson; Masato Ikeda; Lori Lev; Richard Longnecker; Toni Portis
Identification of latent membrane protein 2A (LMP2A) specific targets for treatment and eradication of Epstein-Barr virus (EBV)-associated diseases.
The Journal of antimicrobial chemotherapy 2003;52(2):152-4.
2003: Marisa P McShane; Maureen M Mullen; Keith M Haan; Theodore S Jardetzky; Richard Longnecker
Mutational analysis of the HLA class II interaction with Epstein-Barr virus glycoprotein 42.
Journal of virology 2003;77(13):7655-62.
2003: Akiko Ikeda; Robert G Caldwell; Richard Longnecker; Masato Ikeda
Itchy, a Nedd4 ubiquitin ligase, downregulates latent membrane protein 2A activity in B-cell signaling.
Journal of virology 2003;77(9):5529-34.
2003: Toni Portis; Richard Longnecker
Epstein-Barr virus LMP2A interferes with global transcription factor regulation when expressed during B-lymphocyte development.
Journal of virology 2003;77(1):105-14.
2002: Lori Cooper; Richard Longnecker
Inhibition of host kinase activity altered by the LMP2A signalosome-a therapeutic target for Epstein-Barr virus latency and associated disease.
Antiviral research 2002;56(3):219-31.
2002: Masato Ikeda; Akiko Ikeda; Richard Longnecker
Lysine-independent ubiquitination of Epstein-Barr virus LMP2A.
Virology 2002;300(1):153-9.
2002: Peter Speck; Masato Ikeda; Akiko Ikeda; Howard M Lederman; Richard Longnecker
Signal transduction through the B cell antigen receptor is normal in ataxia-telangiectasia B lymphocytes.
The Journal of biological chemistry 2002;277(6):4123-7.
2002: Maureen M Mullen; Keith M Haan; Richard Longnecker; Theodore S Jardetzky
Structure of the Epstein-Barr virus gp42 protein bound to the MHC class II receptor HLA-DR1.
Molecular cell 2002;9(2):375-85.
2002: Toni Portis; Lori Cooper; Patrick Dennis; Richard Longnecker
The LMP2A signalosome--a therapeutic target for Epstein-Barr virus latency and associated disease.
Frontiers in bioscience : a journal and virtual library 2002;7():d414-26.
2001: Mark Merchant; Richard Longnecker
LMP2A survival and developmental signals are transmitted through Btk-dependent and Btk-independent pathways.
Virology 2001;291(1):46-54.
2001: Keith M Haan; S K Lee; Richard Longnecker
Different functional domains in the cytoplasmic tail of glycoprotein B are involved in Epstein-Barr virus-induced membrane fusion.
Virology 2001;290(1):106-14.
2001: Masato Ikeda; Akiko Ikeda; Richard Longnecker
PY motifs of Epstein-Barr virus LMP2A regulate protein stability and phosphorylation of LMP2A-associated proteins.
Journal of virology 2001;75(12):5711-8.
2001: Keith M Haan; Ashok Aiyar; Richard Longnecker
Establishment of latent Epstein-Barr virus infection and stable episomal maintenance in murine B-cell lines.
Journal of virology 2001;75(6):3016-20.
2001: Mark Merchant; R Swart; Rebecca B Katzman; Masato Ikeda; Akiko Ikeda; Richard Longnecker; Michelle L Dykstra; Susan K Pierce
The effects of the Epstein-Barr virus latent membrane protein 2A on B cell function.
International reviews of immunology 2001;20(6):805-35.
2001: Robert G Caldwell; Richard Longnecker
Detection of immunoglobulin gene rearrangements.
Methods in molecular biology (Clifton, N.J.) 2001;174():423-31.
2001: S Fruehling; Richard Longnecker
In vitro assays for the detection of protein tyrosine phosphorylation and protein tyrosine kinase activities.
Methods in molecular biology (Clifton, N.J.) 2001;174():337-43.
2001: Michelle L Dykstra; Richard Longnecker; Susan K Pierce
Epstein-Barr virus coopts lipid rafts to block the signaling and antigen transport functions of the BCR.
Immunity 2001;14(1):57-67.
2000: Peter Speck; Richard Longnecker
Infection of breast epithelial cells with Epstein-Barr virus via cell-to-cell contact.
Journal of the National Cancer Institute 2000;92(22):1849-51.
2000: Peter Speck; Keith M Haan; Richard Longnecker
Epstein-Barr virus entry into cells.
Virology 2000;277(1):1-5.
2000: R Swart; Ingrid K Ruf; Jeffery T Sample; Richard Longnecker
Latent membrane protein 2A-mediated effects on the phosphatidylinositol 3-Kinase/Akt pathway.
Journal of virology 2000;74(22):10838-45.
2000: Mark Merchant; Robert G Caldwell; Richard Longnecker
The LMP2A ITAM is essential for providing B cells with development and survival signals in vivo.
Journal of virology 2000;74(19):9115-24.
2000: L Longan; Richard Longnecker
Epstein-Barr virus latent membrane protein 2A has no growth-altering effects when expressed in differentiating epithelia.
The Journal of general virology 2000;81(Pt 9):2245-52.
2000: Keith M Haan; Richard Longnecker
Coreceptor restriction within the HLA-DQ locus for Epstein-Barr virus infection.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(16):9252-7.
2000: Richard Longnecker; Mark Merchant; ME Brown; S Fruehling; J O Bickford; Masato Ikeda; Ronald N Harty
WW- and SH3-domain interactions with Epstein-Barr virus LMP2A.
Experimental cell research 2000;257(2):332-40.
2000: Masato Ikeda; Akiko Ikeda; L C Longan; Richard Longnecker
The Epstein-Barr virus latent membrane protein 2A PY motif recruits WW domain-containing ubiquitin-protein ligases.
Virology 2000;268(1):178-91.
2000: Keith M Haan; W W Kwok; Richard Longnecker; Peter Speck
Epstein-Barr virus entry utilizing HLA-DP or HLA-DQ as a coreceptor.
Journal of virology 2000;74(5):2451-4.
2000: Robert G Caldwell; R C Brown; Richard Longnecker
Epstein-Barr virus LMP2A-induced B-cell survival in two unique classes of EmuLMP2A transgenic mice.
Journal of virology 2000;74(3):1101-13.
1999: R Swart; S Fruehling; Richard Longnecker
Tyrosines 60, 64, and 101 of Epstein-Barr virus LMP2A are not essential for blocking B cell signal transduction.
Virology 1999;263(2):485-95.
1999: JM Gabriel; Mark Merchant; T Ohta; Y Ji; Robert G Caldwell; Marilyn J Ramsey; James Tucker; Richard Longnecker; Robert D Nicholls
A transgene insertion creating a heritable chromosome deletion mouse model of Prader-Willi and angelman syndromes.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(16):9258-63.
1999: Peter Speck; K A Kline; P Cheresh; Richard Longnecker
Epstein-Barr virus lacking latent membrane protein 2 immortalizes B cells with efficiency indistinguishable from that of wild-type virus.
The Journal of general virology 1999;80 ( Pt 8)():2193-203.
1999: Peter Speck; Richard Longnecker
Epstein-Barr virus (EBV) infection visualized by EGFP expression demonstrates dependence on known mediators of EBV entry.
Archives of virology 1999;144(6):1123-37.
1998: S Fruehling; R Swart; K M Dolwick; Elisabeth Kremmer; Richard Longnecker
Tyrosine 112 of latent membrane protein 2A is essential for protein tyrosine kinase loading and regulation of Epstein-Barr virus latency.
Journal of virology 1998;72(10):7796-806.
1998: Robert G Caldwell; Joanna Beatrice Wilson; S J Anderson; Richard Longnecker
Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals.
Immunity 1998;9(3):405-11.
1997: S Fruehling; Richard Longnecker
The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction.
Virology 1997;235(2):241-51.
1996: S Fruehling; S K Lee; R Herrold; B Frech; G Laux; Elisabeth Kremmer; Friedrich A Grässer; Richard Longnecker
Identification of latent membrane protein 2A (LMP2A) domains essential for the LMP2A dominant-negative effect on B-lymphocyte surface immunoglobulin signal transduction.
Journal of virology 1996;70(9):6216-26.
1996: R E Herrold; A Marchini; S Fruehling; Richard Longnecker
Glycoprotein 110, the Epstein-Barr virus homolog of herpes simplex virus glycoprotein B, is essential for Epstein-Barr virus replication in vivo.
Journal of virology 1996;70(3):2049-54.
1995: C L Miller; A L Burkhardt; J H Lee; B Stealey; Richard Longnecker; J B Bolen; Elliott Kieff
Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases.
Immunity 1995;2(2):155-66.
1994: C L Miller; J H Lee; Elliott Kieff; A L Burkhardt; J B Bolen; Richard Longnecker
Epstein-Barr virus protein LMP2A regulates reactivation from latency by negatively regulating tyrosine kinases involved in sIg-mediated signal transduction.
Infectious agents and disease 1994;3(2-3):128-36.
1994: C L Miller; J H Lee; Elliott Kieff; Richard Longnecker
An integral membrane protein (LMP2) blocks reactivation of Epstein-Barr virus from latency following surface immunoglobulin crosslinking.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(2):772-6.
1993: B Tomkinson; E Robertson; R Yalamanchili; Richard Longnecker; Elliott Kieff
Epstein-Barr virus recombinants from overlapping cosmid fragments.
Journal of virology 1993;67(12):7298-306.
1993: Richard Longnecker; C L Miller; B Tomkinson; X Q Miao; Elliott Kieff
Deletion of DNA encoding the first five transmembrane domains of Epstein-Barr virus latent membrane proteins 2A and 2B.
Journal of virology 1993;67(8):5068-74.
1993: C L Miller; Richard Longnecker; Elliott Kieff
Epstein-Barr virus latent membrane protein 2A blocks calcium mobilization in B lymphocytes.
Journal of virology 1993;67(6):3087-94.
1993: Richard Longnecker; C L Miller; X Q Miao; B Tomkinson; Elliott Kieff
The last seven transmembrane and carboxy-terminal cytoplasmic domains of Epstein-Barr virus latent membrane protein 2 (LMP2) are dispensable for lymphocyte infection and growth transformation in vitro.
Journal of virology 1993;67(4):2006-13.
1993: A Marchini; Elliott Kieff; Richard Longnecker
Marker rescue of a transformation-negative Epstein-Barr virus recombinant from an infected Burkitt lymphoma cell line: a method useful for analysis of genes essential for transformation.
Journal of virology 1993;67(1):606-9.
1992: Richard Longnecker; C L Miller; X Q Miao; A Marchini; Elliott Kieff
The only domain which distinguishes Epstein-Barr virus latent membrane protein 2A (LMP2A) from LMP2B is dispensable for lymphocyte infection and growth transformation in vitro; LMP2A is therefore nonessential.
Journal of virology 1992;66(11):6461-9.
1992: A L Burkhardt; J B Bolen; E Kieff; Richard Longnecker
An Epstein-Barr virus transformation-associated membrane protein interacts with src family tyrosine kinases.
Journal of virology 1992;66(8):5161-7.
1992: A Marchini; Richard Longnecker; Elliott Kieff
Epstein-Barr virus (EBV)-negative B-lymphoma cell lines for clonal isolation and replication of EBV recombinants.
Journal of virology 1992;66(8):4972-81.
1991: Richard Longnecker; Brian J Druker; Thomas M Roberts; Elliott Kieff
An Epstein-Barr virus protein associated with cell growth transformation interacts with a tyrosine kinase.
Journal of virology 1991;65(7):3681-92.
1990: Alison E Adams; Douglas I Johnson; Richard Longnecker; B F Sloat; John R Pringle
CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae.
The Journal of cell biology 1990;111(1):131-42.
1990: Richard Longnecker; Elliott Kieff
A second Epstein-Barr virus membrane protein (LMP2) is expressed in latent infection and colocalizes with LMP1.
Journal of virology 1990;64(5):2319-26.