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Sagar Lonial

Research Profile

Disorders

Multiple Myeloma

Chemicals & Drugs

Procedures

Phenomena

Recurrence

Concepts & Ideas

Physiology

Drug Resistance, Neoplasm

Anatomy

Tumor Cell Line

Co-author Network

Publications

TOP 3
Sagar Lonial; Rajni Sinha; Claire Torre; Mojtaba Akhtari; Christopher Flowers; Jonathan Kaufman; Hanna J Khoury; Amelia A Langston; Mary J Lechowicz; Edmund K Waller
Mobilization of hematopoietic progenitors from normal donors using the combination of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor results in fewer plasmacytoid dendritic cells in the graft and enhanced donor T cell engraftment with Th1 polarization: results from a randomized clinical trial.
Taro Hitosugi; Peng Jin; Hee-Bum Kang; Sumin Kang; Yibin Kang; Hanna J Khoury; Fadlo R Khuri; Gary Leroy; Sagar Lonial; Jae-Ho Seo; Changliang Shan; Dong M Shin; Yi Wang; Jianxin Xie; Liang Zhang; Lu Zhou; Masa Alečković; Martha L Arellano; Titus Boggon; Georgia Z Chen; Shannon Elf; Jun Fan; Weimin Gong; Ting-Lei Gu; Chuan He; Jing Chen
Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation.
Ajay K Nooka; Daniela Casbourne; Charise Gleason; Sagar Lonial
Relapsed and refractory lymphoid neoplasms and multiple myeloma with a focus on carfilzomib.

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All Publications

2013: Sagar Lonial; Rajni Sinha; Claire Torre; Mojtaba Akhtari; Christopher Flowers; Jonathan Kaufman; Hanna J Khoury; Amelia A Langston; Mary J Lechowicz; Edmund K Waller
Mobilization of hematopoietic progenitors from normal donors using the combination of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor results in fewer plasmacytoid dendritic cells in the graft and enhanced donor T cell engraftment with Th1 polarization: results from a randomized clinical trial.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2013;19(3):460-7.
2013: Taro Hitosugi; Peng Jin; Hee-Bum Kang; Sumin Kang; Yibin Kang; Hanna J Khoury; Fadlo R Khuri; Gary Leroy; Sagar Lonial; Jae-Ho Seo; Changliang Shan; Dong M Shin; Yi Wang; Jianxin Xie; Liang Zhang; Lu Zhou; Masa Alečković; Martha L Arellano; Titus Boggon; Georgia Z Chen; Shannon Elf; Jun Fan; Weimin Gong; Ting-Lei Gu; Chuan He; Jing Chen
Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation.
Nature communications 2013;4():1790.
2013: Ajay K Nooka; Daniela Casbourne; Charise Gleason; Sagar Lonial
Relapsed and refractory lymphoid neoplasms and multiple myeloma with a focus on carfilzomib.
Biologics : targets & therapy 2013;7():13-32.
2013: Sagar Lonial; Jesus F San Miguel
Induction therapy for newly diagnosed multiple myeloma.
Journal of the National Comprehensive Cancer Network : JNCCN 2013;11(1):19-28.
2013: Jonathan L Kaufman; H Jean Khoury; Amelia A Langston; Mary Jo Lechowicz; Sagar Lonial; Karen D Rados; Julie M Vose; Gary B Calandra; Christopher R Flowers; L Becker Hewes; Edmund K Waller
A prospective clinical trial evaluating the safety and efficacy of the combination of rituximab and plerixafor as a mobilization regimen for patients with lymphoma.
Transfusion 2013;53(1):76-84.
2012: David I Lichter; Sagar Lonial; George Mulligan; Ruben Niesvizky; Michael D Pickard; Deborah Ricci; Paul G Richardson; Hongliang Shi; Michael Sintchak; Pieter Sonneveld; Olga Tayber; William L Trepicchio; Helgi van de Velde; Joan Bladé; Jamie Cavenagh; William Dalton; Hadi Danaee; Dixie Esseltine; Thierry Façon; Melissa Alsina; Kenneth C Anderson
Sequence analysis of β-subunit genes of the 20S proteasome in patients with relapsed multiple myeloma treated with bortezomib or dexamethasone.
Blood 2012;120(23):4513-6.
2012: Martha Arellano; Zhengjia Chen; Leonard T Heffner; Amelia Langston; Sagar Lonial; Suchita Pakkala; Lin Pan; Mourad Tighiouart; Elliott Winton; H Jean Khoury
Early clearance of peripheral blood blasts predicts response to induction chemotherapy in acute myeloid leukemia.
Cancer 2012;118(21):5278-82.
2012: David S Siegel; George Somlo; Kevin Song; Edward Stadtmauer; A Keith Stewart; Suzanne Trudel; Ravi Vij; Michael Wang; Sandra Wear; Alvin F Wong; Jeffrey A Zonder; Melissa Alsina; Nizar J Bahlis; Francis Buadi; Asher Chanan-Khan; Andrzej J Jakubowiak; Vishal Kukreti; Lori Kunkel; Sagar Lonial; Thomas Martin; Robert Z Orlowski; Frederic J Reu; Sundar Jagannath
A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma.
Blood 2012;120(14):2817-25.
2012: Ajay Nooka; Sagar Lonial
Sequential or combination therapy for multiple myeloma.
Expert review of hematology 2012;5(5):533-45.
2012: Sundar Jagannath; Andrzej J Jakubowiak; Lori A Kunkel; Sagar Lonial; Robert Z Orlowski; Tony Reiman; George Somlo; A Keith Stewart; Suzanne Trudel; Ravi Vij; Alvin Wong; Nizar J Bahlis; David S Siegel
An open-label single-arm pilot phase II study (PX-171-003-A0) of low-dose, single-agent carfilzomib in patients with relapsed and refractory multiple myeloma.
Clinical lymphoma, myeloma & leukemia 2012;12(5):310-8.
2012: Disni Muringampurath-John; Debra Saxe; Dennis D Weisenburger; Elliott F Winton; Mary J Lechowicz; Sagar Lonial; Morgan McLemore; Martha L Arellano; James O Armitage; Martin Bast; Leon Bernal-Mizrachi; Zhengjia Chen; Christopher R Flowers; Leonard T Heffner; David L Jaye; Jonathan L Kaufman; Hanna J Khoury
Characteristics and outcomes of diffuse large B-cell lymphoma presenting in leukaemic phase.
British journal of haematology 2012;158(5):608-14.
2012: Jeffrey L Wolf; Jeffrey Matous; David Siegel; Ravi Vij; Rafat Abonour; Kenneth C Anderson; Bourras R Bengoudifa; Priscille M Bourquelot; Margarida De Magalhaes-Silverman; Hartmut Goldschmidt; Katharine Hazell; Sagar Lonial
Phase II trial of the pan-deacetylase inhibitor panobinostat as a single agent in advanced relapsed/refractory multiple myeloma.
Leukemia & lymphoma 2012;53(9):1820-3.
2012: Asher Chanan-Khan; Meletios Dimopoulos; Robin Foà; Andrzej Hellmann; Sagar Lonial; Arlene S Swern; Donna Weber; Ivan Borrello; Robert Knight
Lenalidomide in combination with dexamethasone improves survival and time-to-progression in patients ≥65 years old with relapsed or refractory multiple myeloma.
International journal of hematology 2012;96(2):254-62.
2012: Rajni Sinha; Mourad Tighiouart; Kevin Bumpers; Leonard T Heffner; Amanda Hutchison-Rzepka; Jonathan L Kaufman; Hanna Jean Khoury; Nassoma King; Mary Jo Lechowicz; Carol Lewis; Sagar Lonial; Pareen J Shenoy; Christopher R Flowers
A phase 1 dose escalation study of bortezomib combined with rituximab, cyclophosphamide, doxorubicin, modified vincristine, and prednisone for untreated follicular lymphoma and other low-grade B-cell lymphomas.
Cancer 2012;118(14):3538-48.
2012: Sagar Lonial; Jonathan L Kaufman
The era of combination therapy in myeloma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(20):2434-6.
2012: Ravi Vij; Michael Wang; Sandra M Wear; Alvin F Wong; A Keith Stewart; David H Vesole; Melissa Alsina; Nizar J Bahlis; Andrew Belch; Nashat Y Gabrail; Sundar Jagannath; Andrzej J Jakubowiak; Jonathan L Kaufman; Vishal Kukreti; Lori A Kunkel; Peter Lee; Sagar Lonial; Jeffrey V Matous; Kevin T McDonagh; Robert Z Orlowski; Frederic J Reu; Peter Rosen; Michael Sebag; David S Siegel
An open-label, single-arm, phase 2 (PX-171-004) study of single-agent carfilzomib in bortezomib-naive patients with relapsed and/or refractory multiple myeloma.
Blood 2012;119(24):5661-70.
2012: Sagar Lonial; Amitabha Mazumder; Philippe Moreau; Anil K Singhal; L Claire Tsao; Ravi Vij; Christopher Westland; Thierry Facon; Jean-Luc Harousseau; Jonathan L Kaufman; Xavier Leleu; Sundar Jagannath
Elotuzumab in combination with lenalidomide and low-dose dexamethasone in relapsed or refractory multiple myeloma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(16):1953-9.
2012: Olle Ringdén; H Schouten; S Shrestha; M-J Zhang; G T da Silva; A Dispenzieri; Cesar O Freytes; R P Gale; J Gibson; V Gupta; L Holmberg; R Kamble; H Lazarus; Sagar Lonial; P McCarthy; K Meehan; G A Milone; Mats Remberger; P N Hari
Effect of acute and chronic GVHD on relapse and survival after reduced-intensity conditioning allogeneic transplantation for myeloma.
Bone marrow transplantation 2012;47(6):831-7.
2012: Paola Neri; Nizar J Bahlis; Sagar Lonial
Panobinostat for the treatment of multiple myeloma.
Expert opinion on investigational drugs 2012;21(5):733-47.
2012: A Mahindra; J Mikhael; G A Milone; R Munker; R Nath; S Saccaro; L Bik To; J Vela-Ojeda; David H Vesole; D T Vogl; B Wirk; M-J Zhang; J R Berenson; J M Bird; A Dispenzieri; J L Gajewski; Robert Peter Gale; L Holmberg; M E Kalaycio; S Kumar; R A Kyle; H M Lazarus; P Li; Sagar Lonial; P Hari
Hematopoietic cell transplantation for primary plasma cell leukemia: results from the Center for International Blood and Marrow Transplant Research.
Leukemia 2012;26(5):1091-7.
2012: Paul G Richardson; O Sezer; D Siegel; E Terpos; S Usmani; D Vesole; P Voorhees; P Wen; Kenneth C Anderson; H Avet-Loiseau; M Beksac; J Bladé; M Cavo; W J Chng; R Comenzo; M Delforge; M Dimopoulos; B G M Durie; H Einsele; Jean-Luc Harousseau; Sundar Jagannath; J L Jongen; J J Lahuerta; J H Lee; Sagar Lonial; M-V Mateos; A Mazumder; G Merlini; J San Miguel; P Moreau; G Morgan; N Munshi; R Niesvizky; Robert Z Orlowski; Antonio Palumbo; S V Rajkumar; Pieter Sonneveld
Management of treatment-emergent peripheral neuropathy in multiple myeloma.
Leukemia 2012;26(4):595-608.
2012: Disni Muringampurath-John; Michael Toscano; Elliott Winton; Chen Zhengjia; Martha Arellano; Leon Bernal-Mizrachi; Christopher R Flowers; Leonard T Heffner; David L Jaye; Jonathan L Kaufman; Mary-Jo Lechowicz; Sagar Lonial; Morgan McLemore; Hanna Jean Khoury
Rituximab-hyperfractionated cyclophosphamide, vincristine, adriamycin and dexamethasone alternating with high-dose cytarabine and methotrexate for aggressive non-Hodgkin lymphoma.
Leukemia & lymphoma 2012;53(4):725-7.
2012: Cynthia R Giver; David L Jaye; Edmond WALLER; Sagar Lonial
Recovery and rebound of platelet counts in mice after thrombocytopenia induced by combination bortezomib + romidepsin.
Experimental hematology 2012;40(2):95-6.
2011: Taro Hitosugi; Haian Fu; Georgia Z Chen; Ting-Lei Gu; Qingyuan Ge; Sagar Lonial; Katherine Lythgoe; Johannes L Roesel; Roberto D Polakiewicz; Jianxin Xie; Tae-Wook Chung; Sumin Kang; Fadlo R Khuri; Titus J Boggon; Xu Wang; Jun Fan; Jing Chen
Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism.
Molecular cell 2011;44(6):864-77.
2011: Paola Neri; Alexander Klimowicz; Kathy Gratton; Erin Stebner; Adnan Mansoor; Lawrence H Boise; Sagar Lonial; Pierfrancesco Tassone; Douglas A Stewart; Peter Duggan; Jordan Johnson; Li Ren; Nizar J Bahlis
Bortezomib-induced "BRCAness" sensitizes multiple myeloma cells to PARP inhibitors.
Blood 2011;118(24):6368-79.
2011: Jun Fan; Qingyuan Ge; Ting-Lei Gu; Taro Hitosugi; Sumin Kang; Fadlo R Khuri; Sagar Lonial; Roberto D Polakiewicz; Jianxin Xie; Titus Boggon; Georgia Z Chen; Tae-Wook Chung; Jing Chen
Tyrosine phosphorylation of lactate dehydrogenase A is important for NADH/NAD(+) redox homeostasis in cancer cells.
Molecular and cellular biology 2011;31(24):4938-50.
2011: Liqun Zhao; Ping Yue; Fadlo R Khuri; Sagar Lonial; Shi-Yong Sun
The NEDD8-activating enzyme inhibitor, MLN4924, cooperates with TRAIL to augment apoptosis through facilitating c-FLIP degradation in head and neck cancer cells.
Molecular cancer therapeutics 2011;10(12):2415-25.
2011: Paul G Richardson; Robert Schlossman; Peter Sportelli; Jeff Wolf; Jeffrey A Zonder; Jeff Allerton; Michael Bar; Kathleen Colson; John Densmore; Lesa Gardner; Irene M Ghobrial; Teru Hideshima; David Irwin; Andrzej J Jakubowiak; Amrita Krishnan; Jacob Laubach; Sagar Lonial; Tom Martin; Nikhil Munshi; Enrique Poradosu; Noopur Raje; Kenneth C Anderson
Perifosine plus bortezomib and dexamethasone in patients with relapsed/refractory multiple myeloma previously treated with bortezomib: results of a multicenter phase I/II trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(32):4243-9.
2011: Ajay Nooka; Pareen J Shenoy; Rajni Sinha; Sagar Lonial; Christopher R Flowers
Hepatitis C reactivation in patients who have diffuse large B-cell lymphoma treated with rituximab: a case report and review of literature.
Clinical lymphoma, myeloma & leukemia 2011;11(5):379-84.
2011: Jie Li; Sagar Lonial; Jefferson Mark Prichard; Heather Renfroe; Louette Vaughn; Darlene Anderson; Christopher R Flowers; Charise Gleason; Michael Graiser; Ellie Hamilton; Jonathan L Kaufman; Amelia Langston; Mary Jo Lechowicz; Edmond WALLER
Effectiveness and cost analysis of "just-in-time" salvage plerixafor administration in autologous transplant patients with poor stem cell mobilization kinetics.
Transfusion 2011;51(10):2175-82.
2011: Shaji Kumar; Robert A Kyle; Hillard M Lazarus; Peigang Li; Michael Lill; Sagar Lonial; Angelo Maiolino; Navneet S Majhail; Kenneth R Meehan; Gustavo A Milone; Rajneesh Nath; David H Vesole; Ravi Vij; Dan T Vogl; Brendan Weiss; Peter H Wiernik; Baldeep Wirk; Mei-Jie Zhang; Natalie S Callander; Angela Dispenzieri; Cesar O Freytes; Robert Peter Gale; Mehdi Hamadani; Rammurti T Kamble; Amrita Krishnan; Parameswaran N Hari
Trends in allogeneic stem cell transplantation for multiple myeloma: a CIBMTR analysis.
Blood 2011;118(7):1979-88.
2011: Alejo A Morales; David Siefker; Delia M Gutman; Jonathan L Kaufman; Metin Kurtoglu; Kelvin P Lee; Jiangxia Liu; Sagar Lonial; Shannon M Matulis; Lawrence Boise
Distribution of Bim determines Mcl-1 dependence or codependence with Bcl-xL/Bcl-2 in Mcl-1-expressing myeloma cells.
Blood 2011;118(5):1329-39.
2011: Heather Renfroe; Louette Vaughn; Mike Arnold; Christopher R Flowers; Ellie Hamilton; R Donald Harvey; Jonathan L Kaufman; H Jean Khoury; Mary Jo Lechowicz; Sagar Lonial; Edmond WALLER
A randomized clinical trial comparing granulocyte-colony-stimulating factor administration sites for mobilization of peripheral blood stem cells for patients with hematologic malignancies undergoing autologous stem cell transplantation.
Transfusion 2011;51(8):1779-83.
2011: Andrzej J Jakubowiak; Mark S Kaminski; Susan L Kelley; Jacob P Laubach; Sagar Lonial; Melissa A Mietzel; Noopur S Raje; Donna E Reece; Kenneth C Anderson; Tara Anderson; Jennifer C Barrickman; Erica L Campagnaro; Dixie Esseltine; Kent Andrew Griffith; Colleen K Harvey; Craig C Hofmeister; Robert L Schlossman; Craig L Tendler; Sandra M Wear; Todd M Zimmerman; Paul G Richardson
Lenalidomide, bortezomib, pegylated liposomal doxorubicin, and dexamethasone in newly diagnosed multiple myeloma: a phase 1/2 Multiple Myeloma Research Consortium trial.
Blood 2011;118(3):535-43.
2011: Michele Cavo; Meletios A Dimopoulos; Brian G M Durie; Hermann Einsele; Gösta Gahrton; Sundar Jagannath; Hans E Johnsen; Nicolaus Kroeger; Sagar Lonial; Heinz Ludwig; Philippe Moreau; Ruben Niesvizky; Robert Z Orlowski; Antonio Palumbo; S Vincent Rajkumar; Paul G Richardson; Jesus San Miguel; Orhan Sezer; Pieter Sonneveld; David H Vesole; Kenneth C Anderson; Michel Attal; William Bensinger; P Leif Bergsagel; Joan Bladé; Mario Boccadoro
International Myeloma Working Group consensus approach to the treatment of multiple myeloma patients who are candidates for autologous stem cell transplantation.
Blood 2011;117(23):6063-73.
2011: Sascha A Tuchman; Sagar Lonial
High-risk multiple myeloma: does it still exist?
Clinical lymphoma, myeloma & leukemia 2011;11 Suppl 1():S70-6.
2011: Paul G Richardson; Asher A Chanan-Khan; Sagar Lonial; Amrita Y Krishnan; Michael P Carroll; Melissa Alsina; Maher Albitar; David Berman; Marianne Messina; Kenneth C Anderson
Tanespimycin and bortezomib combination treatment in patients with relapsed or relapsed and refractory multiple myeloma: results of a phase 1/2 study.
British journal of haematology 2011;153(6):729-40.
2011: Maurizio Zangari; Fenghuang Zhan; Suzanne Trudel; Ravi Vij; Luhua Wang; Monette Aujay; Nizar Bahlis; Andrew Belch; Tamara Berno; Kristina L Hetherington; Sundar Jagannath; Andrzej Jakubowiak; A Keith Stewart; Vishal Kukreti; Sagar Lonial; Robert Z Orlowski; David Siegel; Seema Singhal; George Somlo; Guido Tricot
Alkaline phosphatase variation during carfilzomib treatment is associated with best response in multiple myeloma patients.
European journal of haematology 2011;86(6):484-7.
2011: Sagar Lonial
Is subcutaneous bortezomib ready for prime time?
Current hematologic malignancy reports 2011;6(2):73-4.
2011: S Vincent Rajkumar; Paul Richardson; Jesús San Miguel; Orhan Sezer; David Siegel; David H Vesole; Jeffrey A Zonder; Kenneth C Anderson; Hervé Avet-Loiseau; Joan Blade; Meletios Dimopoulos; Brian G M Durie; Thierry Facon; Jean-Luc Harousseau; Sundar Jagannath; Robert Kyle; Sagar Lonial; Heinz Ludwig; Nikhil C Munshi; Robert Z Orlowski; Antonio Palumbo
Consensus recommendations for the uniform reporting of clinical trials: report of the International Myeloma Workshop Consensus Panel 1.
Blood 2011;117(18):4691-5.
2011: Sagar Lonial; Lawrence H Boise
Farnesyl transferase inhibitors, autophagy, and proteasome inhibition: synergy for all the right reasons.
Autophagy 2011;7(4):448-9.
2011: Michael A Chapman; Michael S Lawrence; Jonathan J Keats; Kristian Cibulskis; Carrie Sougnez; Anna C Schinzel; Christina L Harview; Jean-Philippe Brunet; Gregory J Ahmann; Mazhar Adli; Kenneth C Anderson; Kristin G Ardlie; Daniel Auclair; Angela Baker; P Leif Bergsagel; Bradley E Bernstein; Yotam Drier; Rafael Fonseca; Stacey B Gabriel; Craig C Hofmeister; Sundar Jagannath; Andrzej J Jakubowiak; Amrita Krishnan; Joan Levy; Ted Liefeld; Sagar Lonial; Scott Mahan; Bunmi Mfuko; Stefano Monti; Louise M Perkins; Robb Onofrio; Trevor J Pugh; S Vincent Rajkumar; Alex H Ramos; David S Siegel; Andrey Sivachenko; A Keith Stewart; Suzanne Trudel; Ravi Vij; Douglas Voet; Wendy Winckler; Todd Zimmerman; John Carpten; Jeffrey M. Trent; William C Hahn; Levi A Garraway; Matthew Meyerson; Eric S Lander; Gad Getz; Todd R Golub
Initial genome sequencing and analysis of multiple myeloma.
Nature 2011;471(7339):467-72.
2011: Sagar Lonial; Constantine S Mitsiades; Paul G Richardson
Treatment options for relapsed and refractory multiple myeloma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(6):1264-77.
2011: Jonathan L Kaufman; Sagar Lonial
Putting the E (evidence) in a new Era for myeloma.
Leukemia & lymphoma 2011;52(3):349-50.
2011: Paul G Richardson; Constantine S Mitsiades; Jacob P Laubach; Sagar Lonial; Asher Chanan-Khan; Kenneth C Anderson
Inhibition of heat shock protein 90 (HSP90) as a therapeutic strategy for the treatment of myeloma and other cancers.
British journal of haematology 2011;152(4):367-79.
2011: C R Giver; D L Jaye; E K Waller; J L Kaufman; Sagar Lonial
Rapid recovery from panobinostat (LBH589)-induced thrombocytopenia in mice involves a rebound effect of bone marrow megakaryocytes.
Leukemia 2011;25(2):362-5.
2011: Donna Reece; Dan Sullivan; Sagar Lonial; Ann F Mohrbacher; Gurkamal Chatta; Chaim Shustik; Howard Burris; Karthik Venkatakrishnan; Rachel Neuwirth; William J Riordan; Michael Karol; Lisa L Von Moltke; Milin Acharya; Peter Zannikos; A Keith Stewart
Pharmacokinetic and pharmacodynamic study of two doses of bortezomib in patients with relapsed multiple myeloma.
Cancer chemotherapy and pharmacology 2011;67(1):57-67.
2010: Ebenezer David; Jonathan L Kaufman; Christopher R Flowers; Katherine Schafer-Hales; Claire Torre; Jing Chen; Adam I Marcus; Shi-Yong Sun; Lawrence H Boise; Sagar Lonial
Tipifarnib sensitizes cells to proteasome inhibition by blocking degradation of bortezomib-induced aggresomes.
Blood 2010;116(24):5285-8.
2010: Mojtaba Akhtari; Cynthia R Giver; Zahir Ali; Christopher R Flowers; Charise L Gleason; Christopher D Hillyer; Jonathan Kaufman; H Jean Khoury; Amelia A Langston; Mary Jo Lechowicz; Sagar Lonial; Heather M Renfroe; John D Roback; Mourad Tighiouart; Louette Vaughn; Edmund K Waller
Receiver operating characteristic curve analysis of circulating blood dendritic cell precursors and T cells predicts response to extracorporeal photopheresis in patients with chronic graft-versus-host disease.
Transfusion 2010;50(11):2424-31.
2010: Sagar Lonial; Jonathan Kaufman; Mourad Tighiouart; Ajay Nooka; Amelia A Langston; Leonard T Heffner; Claire Torre; Stephanie McMillan; Heather Renfroe; R Donald Harvey; Mary J Lechowicz; H Jean Khoury; Christopher R Flowers; Edmond WALLER
A phase I/II trial combining high-dose melphalan and autologous transplant with bortezomib for multiple myeloma: a dose- and schedule-finding study.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(20):5079-86.
2010: Jonathan Kaufman; Sagar Lonial
Melphalan or no melphalan: that is the question.
Oncology (Williston Park, N.Y.) 2010;24(11):1000-1.
2010: Sundar Jagannath; Meletios A Dimopoulos; Sagar Lonial
Combined proteasome and histone deacetylase inhibition: A promising synergy for patients with relapsed/refractory multiple myeloma.
Leukemia research 2010;34(9):1111-8.
2010: Sagar Lonial
The White House crusade against ... MGUS?
Blood 2010;116(7):1020-1.
2010: Frits van Rhee; Luis Fayad; Peter Voorhees; Richard Furman; Sagar Lonial; Hossein Borghaei; Lubomir Sokol; Julie Crawford; Mark Cornfeld; Ming Qi; Xiang Qin; Jennifer Herring; Corey Casper; Razelle Kurzrock
Siltuximab, a novel anti-interleukin-6 monoclonal antibody, for Castleman's disease.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(23):3701-8.
2010: Paul G Richardson; Edie Weller; Sagar Lonial; Andrzej J Jakubowiak; Sundar Jagannath; Noopur S Raje; David Avigan; Wanling Xie; Irene M Ghobrial; Robert Schlossman; Amitabha Mazumder; Nikhil C Munshi; David H Vesole; Robin Joyce; Jonathan L Kaufman; Deborah Doss; Diane L Warren; Laura E Lunde; Sarah Kaster; Carol Delaney; Teru Hideshima; Constantine S Mitsiades; Robert Knight; Dixie Esseltine; Kenneth C Anderson
Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma.
Blood 2010;116(5):679-86.
2010: Jonathan L Kaufman; Ajay Nooka; Mark Vrana; Charise Gleason; Leonard T Heffner; Sagar Lonial
Bortezomib, thalidomide, and dexamethasone as induction therapy for patients with symptomatic multiple myeloma: a retrospective study.
Cancer 2010;116(13):3143-51.
2010: James R Berenson; Kenneth C Anderson; Robert A Audell; Ralph V Boccia; Morton Coleman; Meletios A Dimopoulos; Matthew T Drake; Rafael Fonseca; Jean-Luc Harousseau; Douglas Joshua; Sagar Lonial; Ruben Niesvizky; Antonio Palumbo; G David Roodman; Jesus F San-Miguel; Seema Singhal; Donna M Weber; Maurizio Zangari; Eric Wirtschafter; Ori Yellin; Robert A Kyle
Monoclonal gammopathy of undetermined significance: a consensus statement.
British journal of haematology 2010;150(1):28-38.
2010: Ajay Nooka; Charise Gleason; Sagar Lonial
Improving induction therapy in multiple myeloma.
Current hematologic malignancy reports 2010;5(3):119-28.
2010: Sagar Lonial
Future directions in immunomodulatory therapy.
Medical oncology (Northwood, London, England) 2010;27 Suppl 1():S62-6.
2010: Chunyang Li; Shuzhen Chen; Ping Yue; Xingming Deng; Sagar Lonial; Fadlo R Khuri; Shi-Yong Sun
Proteasome inhibitor PS-341 (bortezomib) induces calpain-dependent IkappaB(alpha) degradation.
The Journal of biological chemistry 2010;285(21):16096-104.
2010: Sagar Lonial
Frontline regimens for multiple myeloma patients.
Clinical advances in hematology & oncology : H&O 2010;8(5):331-2.
2010: Sagar Lonial
Presentation and risk stratification--improving prognosis for patients with multiple myeloma.
Cancer treatment reviews 2010;36 Suppl 2():S12-7.
2010: Rafael Fonseca; Paul G Richardson; Sergio Giralt; Sagar Lonial; S Vincent Rajkumar; A Keith Stewart; William Bensinger; George Somlo; Robert Vescio; Joseph Mikhael; Craig Reeder; Rodger Tiedemann; Guido Tricot; Robert Rifkin; John Shaughnessy; Nikhil Munshi; Noopur Raje; Irene Ghobrial; Jacob Laubach; Robert Schlossman; Steven Treon; Anuj Mahindra; David Avigan; Jacalyn Rosenblatt; Sundar Jagannath; Ruben Niesvizky; Heather Landau; Selina Chen-Kiang; David S Siegel; Todd Zimmerman; Jayesh Mehta; David Vesole; Steven Rosen; Craig Hofmeister; Martha Lacy; Angela Dispenzieri; Ivan Borrello; Suzanne R Hayman; Shaji Kumar; Frances Buadi; David Dingli; Stephen Russell; Melissa Alsina Melissa Alsina; Hugo Fernandez; Vivek Roy; Denise Pereira; Edward Stadtmauer; Ravi Vij; Andrzej Jakubowiak; Suzanne Lentzsch; Kevin Song; Suzanne Trudel; Christine Chen; Donna Reece; Douglas Stewart; Seema Singhal; Raymond Comenzo; Morie A Gertz; Philip R Greipp; Brian Durie; Bart Barlogie; Kenneth C Anderson; William Dalton; Morton Coleman; Susie Novis; Robert A Kyle
Conflicts of interest, authorship, and disclosures in industry-related scientific publications.
Mayo Clinic proceedings. Mayo Clinic 2010;85(2):197-9; author reply 201-4.
2010: Nina Shah; Sagar Lonial
Evidence-based mini-review: treatment options for patients with relapsed/refractory myeloma previously treated with novel agents and high-dose chemotherapy and autologous stem-cell transplantation.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2010;2010():310-3.
2010: Sagar Lonial
Relapsed multiple myeloma.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2010;2010():303-9.
2009: Lei Fu; Young-Ae Kim; Xuerong Wang; Xiaoyun Wu; Ping Yue; Sagar Lonial; Fadlo R Khuri; Shi-Yong Sun
Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy.
Cancer research 2009;69(23):8967-76.
2009: Ajay Nooka; Jonathan Kaufman; Sagar Lonial
The importance of complete response in outcomes in myeloma.
Cancer journal (Sudbury, Mass.) 2009;15(6):465-72.
2009: R D Harvey; J Nettles; Binghe Wang; S-Y Sun; Sagar Lonial
Commentary on Perrone et al.: 'vitamin C: not for breakfast anymore...if you have myeloma'.
Leukemia 2009;23(11):1939-40.
2009: Charise Gleason; Ajay Nooka; Sagar Lonial
Supportive therapies in multiple myeloma.
Journal of the National Comprehensive Cancer Network : JNCCN 2009;7(9):971-9.
2009: Sergio Giralt; E A Stadtmauer; Jean-Luc Harousseau; Antonio Palumbo; W Bensinger; R L Comenzo; S Kumar; N C Munshi; A Dispenzieri; R Kyle; G Merlini; J San Miguel; Heinz Ludwig; R Hajek; Sundar Jagannath; J Blade; Sagar Lonial; M A Dimopoulos; H Einsele; Bart Barlogie; Kenneth C Anderson; M Gertz; M Attal; P Tosi; Pieter Sonneveld; Mario Boccadoro; G Morgan; O Sezer; M V Mateos; M Cavo; D Joshua; I Turesson; Wesley Chen; K Shimizu; R Powles; Paul G Richardson; R Niesvizky; S V Rajkumar; B G M Durie
International myeloma working group (IMWG) consensus statement and guidelines regarding the current status of stem cell collection and high-dose therapy for multiple myeloma and the role of plerixafor (AMD 3100).
Leukemia 2009;23(10):1904-12.
2009: Antonio Palumbo; O Sezer; R Kyle; J S Miguel; Robert Z Orlowski; P Moreau; R Niesvizky; G Morgan; R Comenzo; Pieter Sonneveld; S Kumar; R Hajek; Sergio Giralt; S Bringhen; Kenneth C Anderson; Paul G Richardson; M Cavo; F Davies; J Bladé; H Einsele; M A Dimopoulos; A Spencer; A Dispenzieri; T Reiman; K Shimizu; J H Lee; M Attal; Mario Boccadoro; M Mateos; W Chen; Heinz Ludwig; D Joshua; J Chim; V Hungria; I Turesson; B G M Durie; Sagar Lonial
International Myeloma Working Group guidelines for the management of multiple myeloma patients ineligible for standard high-dose chemotherapy with autologous stem cell transplantation.
Leukemia 2009;23(10):1716-30.
2009: Shaji Kumar; Sergio Giralt; Edward A Stadtmauer; Jean-Luc Harousseau; Antonio Palumbo; William Bensinger; Raymond Comenzo; Suzanne Lentzsch; Nikhil Munshi; Ruben Niesvizky; Jesús San Miguel; Heinz Ludwig; Leif Bergsagel; Joan Blade; Sagar Lonial; Kenneth C Anderson; Patrizia Tosi; Pieter Sonneveld; Orhan Sezer; David H Vesole; Michele Cavo; Hermann Einsele; Paul G Richardson; Brian G M Durie; S Vincent Rajkumar
Mobilization in myeloma revisited: IMWG consensus perspectives on stem cell collection following initial therapy with thalidomide-, lenalidomide-, or bortezomib-containing regimens.
Blood 2009;114(9):1729-35.
2009: Paul G Richardson; Wanling Xie; Constantine S Mitsiades; Asher A Chanan-Khan; Sagar Lonial; Hani Hassoun; David Avigan; Anne Louise Oaklander; David J Kuter; Patrick Y Wen; Santosh kesari; Hannah R Briemberg; Robert Schlossman; Nikhil C Munshi; L Thompson Heffner; Deborah Doss; Dixie Esseltine; Edie Weller; Kenneth C Anderson; Anthony A Amato
Single-agent bortezomib in previously untreated multiple myeloma: efficacy, characterization of peripheral neuropathy, and molecular correlations with response and neuropathy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(21):3518-25.
2009: Sagar Lonial
Risky business in myeloma.
Blood 2009;114(3):496-7.
2009: Veerappan Subramaniyam; Edmond WALLER; Jonathan R Murrow; Amita Manatunga; Sagar Lonial; Karthikeswar Kasirajan; Diane Sutcliffe; Wayne Harris; W. Robert Taylor; Wayne R Alexander; Arshed A Quyyumi
Bone marrow mobilization with granulocyte macrophage colony-stimulating factor improves endothelial dysfunction and exercise capacity in patients with peripheral arterial disease.
American heart journal 2009;158(1):53-60.e1.
2009: Sagar Lonial; Jamie Cavenagh
Emerging combination treatment strategies containing novel agents in newly diagnosed multiple myeloma.
British journal of haematology 2009;145(6):681-708.
2009: Jonathan Kaufman; Sagar Lonial
Treatment of multiple myeloma: whence truth over belief?
Oncology (Williston Park, N.Y.) 2009;23(5):420, 423.
2009: Jonathan Kaufman; Charise Gleason; Sagar Lonial
Treatment of relapsed and refractory myeloma.
Current hematologic malignancy reports 2009;4(2):99-107.
2009: Sumin Kang; Shannon Elf; Shaozhong Dong; Taro Hitosugi; Katherine Lythgoe; Ailan Guo; Hong Ruan; Sagar Lonial; Hanna J Khoury; Ifor Williams; Benjamin H Lee; Johannes L Roesel; Gerard Karsenty; André Hanauer; Jack Taunton; Titus Boggon; Ting-Lei Gu; Jing Chen
Fibroblast growth factor receptor 3 associates with and tyrosine phosphorylates p90 RSK2, leading to RSK2 activation that mediates hematopoietic transformation.
Molecular and cellular biology 2009;29(8):2105-17.
2009: Paul G Richardson; Pieter Sonneveld; Michael W Schuster; Edward A Stadtmauer; Thierry Facon; Jean-Luc Harousseau; Dina Ben-Yehuda; Sagar Lonial; Hartmut Goldschmidt; Donna Reece; Joan Bladé; Mario Boccadoro; Jamie Cavenagh; Anthony Boral; Dixie Esseltine; Patrick Y Wen; Anthony A Amato; Kenneth C Anderson; Jesus San Miguel
Reversibility of symptomatic peripheral neuropathy with bortezomib in the phase III APEX trial in relapsed multiple myeloma: impact of a dose-modification guideline.
British journal of haematology 2009;144(6):895-903.
2009: A Goy; S H Bernstein; B S Kahl; Benjamin Djulbegovic; M J Robertson; S de Vos; E Epner; A Krishnan; J P Leonard; Sagar Lonial; S Nasta; O A O'Connor; H Shi; A L Boral; Richard I Fisher
Bortezomib in patients with relapsed or refractory mantle cell lymphoma: updated time-to-event analyses of the multicenter phase 2 PINNACLE study.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2009;20(3):520-5.
2009: A Dispenzieri; R Kyle; G Merlini; J S Miguel; Heinz Ludwig; R Hajek; Antonio Palumbo; Sundar Jagannath; J Blade; Sagar Lonial; M Dimopoulos; R Comenzo; H Einsele; Bart Barlogie; Kenneth C Anderson; M Gertz; Jean-Luc Harousseau; M Attal; P Tosi; Pieter Sonneveld; Mario Boccadoro; G Morgan; Paul G Richardson; O Sezer; M V Mateos; M Cavo; D Joshua; I Turesson; W Chen; K Shimizu; R Powles; S V Rajkumar; B G M Durie
International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma and related disorders.
Leukemia 2009;23(2):215-24.
2009: Paul G Richardson; J San-Miguel; Sagar Lonial; D Reece; Andrzej J Jakubowiak; M Hussein; Sundar Jagannath; C S Mitsiades; N Raje; J Kaufman; D Avigan; I Ghobrial; R L Schlossman; N Munshi; W Dalton; Kenneth C Anderson
The research mission in myeloma.
Leukemia 2009;23(2):422-3; author reply 423-4.
2009: Taro Hitosugi; Sumin Kang; Matthew G Vander Heiden; Tae-Wook Chung; Shannon Elf; Katherine Lythgoe; Shaozhong Dong; Sagar Lonial; Xu Wang; Georgia Z Chen; Jianxin Xie; Ting-Lei Gu; Roberto D Polakiewicz; Johannes L Roesel; Titus Boggon; Fadlo R Khuri; D Gary Gilliland; Lewis C Cantley; Jonathan Kaufman; Jing Chen
Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth.
Science signaling 2009;2(97):ra73.
2008: Asher Chanan-Khan; Pieter Sonneveld; Michael W Schuster; Edward A Stadtmauer; Thierry Facon; Jean-Luc Harousseau; Dina Ben-Yehuda; Sagar Lonial; Hartmut Goldschmidt; Donna Reece; Rachel Neuwirth; Kenneth C Anderson; Paul G Richardson
Analysis of herpes zoster events among bortezomib-treated patients in the phase III APEX study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(29):4784-90.
2008: Sagar Lonial; Paul G Richardson; Jesús San Miguel; Pieter Sonneveld; Michael W Schuster; Joan Bladé; Jamie Cavenagh; S Vincent Rajkumar; Andrzej J Jakubowiak; Dixie Esseltine; Kenneth C Anderson; Jean-Luc Harousseau
Characterisation of haematological profiles and low risk of thromboembolic events with bortezomib in patients with relapsed multiple myeloma.
British journal of haematology 2008;143(2):222-9.
2008: S Murali; Elliott F Winton; Edmond WALLER; Leonard T Heffner; Sagar Lonial; C Flowers; J Kaufman; M Arellano; M J Lechowicz; Karen P Mann; H J Khoury; Amelia A Langston
Long-term progression-free survival after early autologous transplantation for mantle-cell lymphoma.
Bone marrow transplantation 2008;42(8):529-34.
2008: Sagar Lonial; Claire Torre; Ebenezer David; Wayne Harris; Martha Arellano; Edmond WALLER
Regulation of alloimmune responses by dendritic cell subsets.
Experimental hematology 2008;36(10):1309-17.
2008: Ebenezer David; Rajni Sinha; Jing Chen; Shi-Yong Sun; Jonathan L Kaufman; Sagar Lonial
Perifosine synergistically enhances TRAIL-induced myeloma cell apoptosis via up-regulation of death receptors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(16):5090-8.
2008: Sagar Lonial
Practical considerations for multiple myeloma: an overview of recent data and current options.
Clinical lymphoma & myeloma 2008;8 Suppl 4():S144-8.
2008: Jeannine Silberman; Sagar Lonial
Review of peripheral neuropathy in plasma cell disorders.
Hematological oncology 2008;26(2):55-65.
2008: A Mazumder; J Kaufman; R Niesvizky; Sagar Lonial; D Vesole; Sundar Jagannath
Effect of lenalidomide therapy on mobilization of peripheral blood stem cells in previously untreated multiple myeloma patients.
Leukemia 2008;22(6):1280-1; author reply 1281-2.
2008: Jesús F San Miguel; Paul G Richardson; Pieter Sonneveld; M W Schuster; David Irwin; E A Stadtmauer; T Facon; Jean-Luc Harousseau; D Ben-Yehuda; Sagar Lonial; H Goldschmidt; D Reece; Joan Bladé; Mario Boccadoro; J D Cavenagh; R Neuwirth; A L Boral; Dixie Esseltine; Kenneth C Anderson
Efficacy and safety of bortezomib in patients with renal impairment: results from the APEX phase 3 study.
Leukemia 2008;22(4):842-9.
2008: Sagar Lonial; Morie A Gertz
Eliminating the complete response penalty from myeloma response assessment.
Blood 2008;111(6):3297-8.
2008: Martha Arellano; Sagar Lonial
Clinical uses of GM-CSF, a critical appraisal and update.
Biologics : targets & therapy 2008;2(1):13-27.
2008: Shaozhong Dong; Sumin Kang; Sagar Lonial; H J Khoury; J Viallet; Jing Chen
Targeting 14-3-3 sensitizes native and mutant BCR-ABL to inhibition with U0126, rapamycin and Bcl-2 inhibitor GX15-070.
Leukemia 2008;22(3):572-7.
2008: Sumin Kang; Shaozhong Dong; Ailan Guo; Hong Ruan; Sagar Lonial; Hanna Jean Khoury; Ting-Lei Gu; Jing Chen
Epidermal growth factor stimulates RSK2 activation through activation of the MEK/ERK pathway and src-dependent tyrosine phosphorylation of RSK2 at Tyr-529.
The Journal of biological chemistry 2008;283(8):4652-7.
2008: S Pierson Gladney; Sagar Lonial; Jonathan L Kaufman
Multiple myeloma presenting with advanced renal failure: a case report and new treatment options.
Clinical lymphoma & myeloma 2008;8(1):52-4.
2008: Antonio Palumbo; S V Rajkumar; M A Dimopoulos; Paul G Richardson; J San Miguel; Bart Barlogie; Jean-Luc Harousseau; Jeffrey A Zonder; M Cavo; M Zangari; M Attal; A Belch; S Knop; D Joshua; O Sezer; Heinz Ludwig; D Vesole; J Bladé; R Kyle; J Westin; D Weber; S Bringhen; R Niesvizky; A Waage; M von Lilienfeld-Toal; Sagar Lonial; G J Morgan; Robert Z Orlowski; K Shimizu; Kenneth C Anderson; Mario Boccadoro; B G Durie; Pieter Sonneveld; M A Hussein
Prevention of thalidomide- and lenalidomide-associated thrombosis in myeloma.
Leukemia 2008;22(2):414-23.
2007: Sagar Lonial
Multiple myeloma: novel approaches for relapsed disease.
Clinical lymphoma & myeloma 2007;8 Suppl 1():S18-23.
2007: R Donald Harvey; Sagar Lonial
PI3 kinase/AKT pathway as a therapeutic target in multiple myeloma.
Future oncology (London, England) 2007;3(6):639-47.
2007: Donna M Weber; Christine Chen; Ruben Niesvizky; Michael Wang; Andrew Belch; Edward A Stadtmauer; David Siegel; Ivan Borrello; S Vincent Rajkumar; Asher Chanan-Khan; Sagar Lonial; Zhinuan Yu; John Patin; Marta Olesnyckyj; Jerome B Zeldis; Robert D Knight
Lenalidomide plus dexamethasone for relapsed multiple myeloma in North America.
The New England journal of medicine 2007;357(21):2133-42.
2007: Paul G Richardson; Pieter Sonneveld; Michael Schuster; David Irwin; Edward A Stadtmauer; Thierry Facon; Jean-Luc Harousseau; Dina Ben-Yehuda; Sagar Lonial; Hartmut Goldschmidt; Donna Reece; Jesus San Miguel; Joan Bladé; Mario Boccadoro; Jamie Cavenagh; Melissa Alsina; S Vincent Rajkumar; Martha Lacy; Andrzej J Jakubowiak; William Dalton; Anthony Boral; Dixie Esseltine; David P Schenkein; Kenneth C Anderson
Extended follow-up of a phase 3 trial in relapsed multiple myeloma: final time-to-event results of the APEX trial.
Blood 2007;110(10):3557-60.
2007: Edward A Stadtmauer; Sagar Lonial; David H Vesole; Rafat Abonour; Melissa Alsina; Ashraf Badros; Raymond Comenzo; Brian G M Durie; Sergio Giralt; Mohamad Hussein; Andrzej J Jakubowiak; Jayesh Mehta; Ruben Niesvizky; Robert Z Orlowski; David Siegel; Seema Singhal; Robert A Vescio; Michael Wang; Maurizio Zangari; Nikhil C Munshi
A practical guide to achieving and maintaining the best response to lenalidomide in multiple myeloma: roundtable proceedings.
Clinical advances in hematology & oncology : H&O 2007;5(10 Suppl 15):7-19, quiz 21-2.
2007: Ronald Mihelic; Jonathan Kaufman; Sagar Lonial; Christopher Flowers
Maintenance therapy in lymphoma.
Clinical lymphoma & myeloma 2007;7(8):507-13.
2007: Sagar Lonial
Complete remission of multiple myeloma.
Clinical advances in hematology & oncology : H&O 2007;5(9):671-2, 675.
2007: Sumin Kang; Shaozhong Dong; Ting-Lei Gu; Ailan Guo; Michael S Cohen; Sagar Lonial; Hanna Jean Khoury; Doriano Fabbro; D Gary Gilliland; P Leif Bergsagel; Jack Taunton; Roberto D Polakiewicz; Jing Chen
FGFR3 activates RSK2 to mediate hematopoietic transformation through tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway.
Cancer cell 2007;12(3):201-14.
2007: Heath Acuff Elrod; Yi-Dan Lin; Ping Yue; Xuerong Wang; Sagar Lonial; Fadlo R Khuri; Shi-Yong Sun
The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway.
Molecular cancer therapeutics 2007;6(7):2029-38.
2007: Shaozhong Dong; Sumin Kang; Ting-Lei Gu; Sean Kardar; Haian Fu; Sagar Lonial; Hanna Jean Khoury; Fadlo R Khuri; Jing Chen
14-3-3 Integrates prosurvival signals mediated by the AKT and MAPK pathways in ZNF198-FGFR1-transformed hematopoietic cells.
Blood 2007;110(1):360-9.
2007: Paul G Richardson; Pieter Sonneveld; Michael W Schuster; David Irwin; Edward A Stadtmauer; Thierry Facon; Jean-Luc Harousseau; Dina Ben-Yehuda; Sagar Lonial; Jesús F San Miguel; Jamie Cavenagh; Kenneth C Anderson
Safety and efficacy of bortezomib in high-risk and elderly patients with relapsed multiple myeloma.
British journal of haematology 2007;137(5):429-35.
2007: R Mihelic; Jonathan L Kaufman; Sagar Lonial
Maintenance therapy in multiple myeloma.
Leukemia 2007;21(6):1150-7.
2007: Xiangguo Liu; Ping Yue; Shuzhen Chen; Liping Hu; Sagar Lonial; Fadlo R Khuri; Shi-Yong Sun
The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells.
Cancer research 2007;67(10):4981-8.
2007: Yuanzheng Qiu; Xiangguo Liu; Wei Zou; Ping Yue; Sagar Lonial; Fadlo R Khuri; Shi-Yong Sun
The farnesyltransferase inhibitor R115777 up-regulates the expression of death receptor 5 and enhances TRAIL-induced apoptosis in human lung cancer cells.
Cancer research 2007;67(10):4973-80.
2007: Christopher Flowers; Roni Glover; Sagar Lonial; Otis W Brawley
Racial differences in the incidence and outcomes for patients with hematological malignancies.
Current problems in cancer 2007;31(3):182-201.
2007: Michelle L Hicks; Sagar Lonial; Amelia A Langston; Christopher Flowers; John D Roback; Kenneth J Smith; Sarah Mossavi Sai; Diane Teagarden; Ellie S Hamilton; Edmond WALLER; Jonathan Kaufman
Optimizing the timing of chemotherapy for mobilizing autologous blood hematopoietic progenitor cells.
Transfusion 2007;47(4):629-35.
2007: Asher Chanan-Khan; Jonathan L Kaufman; Jayesh Mehta; Paul G Richardson; Kena C Miller; Sagar Lonial; Nikhil C Munshi; Robert Schlossman; Joseph Tariman; Seema Singhal
Activity and safety of bortezomib in multiple myeloma patients with advanced renal failure: a multicenter retrospective study.
Blood 2007;109(6):2604-6.
2007: Sagar Lonial
Designing risk-adapted therapy for multiple myeloma: the Mayo perspective.
Mayo Clinic proceedings. Mayo Clinic 2007;82(3):279-81.
2006: Sagar Lonial
Management of toxicities associated with bortezomib.
Oncology (Williston Park, N.Y.) 2006;20(12):1592-3, 1597.
2006: Richard I Fisher; Steven H Bernstein; Brad S Kahl; Benjamin Djulbegovic; Michael J Robertson; Sven de Vos; Elliot Epner; Amrita Krishnan; John P Leonard; Sagar Lonial; Edward A Stadtmauer; Owen A O'Connor; Hongliang Shi; Anthony Boral; Andre Goy
Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(30):4867-74.
2006: G Kesava Reddy; Tariq I Mughal; Sagar Lonial
Optimizing the management of treatment-related peripheral neuropathy in patients with multiple myeloma.
Supportive cancer therapy 2006;4(1):19-22.
2006: Sagar Lonial; Martha L Arellano; Don Hutcherson; Amelia A Langston; Christopher Flowers; Leonard T Heffner; Elliott F Winton; Mary Jo Lechowicz; Edmond WALLER
Results of a clinical phase I dose-escalation study of cytarabine in combination with fixed-dose vinorelbine, paclitaxel, etoposide and cisplatin for the treatment of relapsed/refractory lymphoma.
Leukemia & lymphoma 2006;47(10):2155-62.
2006: Brett T Brinker; Edmond WALLER; Traci Leong; Leonard T Heffner; Istvan Redei; Amelia A Langston; Sagar Lonial
Maintenance therapy with thalidomide improves overall survival after autologous hematopoietic progenitor cell transplantation for multiple myeloma.
Cancer 2006;106(10):2171-80.
2006: Rajni Sinha; Sagar Lonial
Novel treatment approaches for patients with relapsed and refractory multiple myeloma.
Current treatment options in oncology 2006;7(3):246-57.
2006: Jonathan L Kaufman; Sagar Lonial
Proteasome inhibition: novel therapy for multiple myeloma.
Onkologie 2006;29(4):162-8.
2006: Rajni Sinha; Jonathan L Kaufman; Sagar Lonial
Novel treatment approaches for patients with multiple myeloma.
Clinical lymphoma & myeloma 2006;6(4):281-8.
2006: Jesús San Miguel; Joan Bladé; Mario Boccadoro; Jamie Cavenagh; Axel Glasmacher; Sundar Jagannath; Sagar Lonial; Robert Z Orlowski; Pieter Sonneveld; Heinz Ludwig
A practical update on the use of bortezomib in the management of multiple myeloma.
The oncologist 2006;11(1):51-61.
2006: Wei Zou; Ping Yue; Na Lin; Min He; Zhongmei Zhou; Sagar Lonial; Fadlo R Khuri; Binghe Wang; Shi-Yong Sun
Vitamin C inactivates the proteasome inhibitor PS-341 in human cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(1):273-80.
2005: Ebenezer David; Shi-Yong Sun; Edmond WALLER; Jing Chen; Fadlo R Khuri; Sagar Lonial
The combination of the farnesyl transferase inhibitor lonafarnib and the proteasome inhibitor bortezomib induces synergistic apoptosis in human myeloma cells that is associated with down-regulation of p-AKT.
Blood 2005;106(13):4322-9.
2005: Sagar Lonial; Edmond WALLER; Paul G Richardson; Sundar Jagannath; Robert Z Orlowski; Cynthia R Giver; David L Jaye; Dixil Francis; Sara Giusti; Claire Torre; Bart Barlogie; James R Berenson; Seema Singhal; David P Schenkein; Dixie Esseltine; Jessica Anderson; Hugh Xiao; Leonard T Heffner; Kenneth C Anderson
Risk factors and kinetics of thrombocytopenia associated with bortezomib for relapsed, refractory multiple myeloma.
Blood 2005;106(12):3777-84.
2005: Maureen Haas; Sagar Lonial
Targeted therapy for haematological malignancies: clinical update from the American Society of Hematology, 2004.
Expert opinion on investigational drugs 2005;14(9):1161-9.
2005: Paul G Richardson; Pieter Sonneveld; Michael W Schuster; David Irwin; Edward A Stadtmauer; Thierry Facon; Jean-Luc Harousseau; Dina Ben-Yehuda; Sagar Lonial; Hartmut Goldschmidt; Donna Reece; Jesús F San Miguel; Joan Bladé; Mario Boccadoro; Jamie Cavenagh; William S Dalton; Anthony Boral; Dixie Esseltine; Jane B Porter; David P Schenkein; Kenneth C Anderson
Bortezomib or high-dose dexamethasone for relapsed multiple myeloma.
The New England journal of medicine 2005;352(24):2487-98.
2005: Jason J Everly; Sagar Lonial
Immunomodulatory effects of human recombinant granulocyte-macrophage colony-stimulating factor (rhuGM-CSF): evidence of antitumour activity.
Expert opinion on biological therapy 2005;5(3):293-311.
2004: Sagar Lonial; Michelle Hicks; Hilary Rosenthal; Amelia A Langston; Istvan Redei; Claire Torre; Mary Duenzl; Bonita Feinstein; Judy Cherry; Edmond WALLER
A randomized trial comparing the combination of granulocyte-macrophage colony-stimulating factor plus granulocyte colony-stimulating factor versus granulocyte colony-stimulating factor for mobilization of dendritic cell subsets in hematopoietic progenitor cell products.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2004;10(12):848-57.
2004: Edmond WALLER; Cynthia R Giver; Hilary Rosenthal; Jyoti Somani; Amelia A Langston; Sagar Lonial; John D Roback; Jian-Ming Li; Mohammad S Hossain; Istvan Redei
Facilitating T-cell immune reconstitution after haploidentical transplantation in adults.
Blood cells, molecules & diseases 2004;33(3):233-7.
2004: Jonathan Kaufman; Sagar Lonial
Multiple myeloma: the role of transplant and novel treatment strategies.
Seminars in oncology 2004;31(2 Suppl 4):99-105.
2004: Sagar Lonial
Immunomodulation: the role of hematopoietic cytokines.
Supportive cancer therapy 2004;1(2):80-8.
2004: Cynthia R Giver; Jian-Ming Li; Mohammad S Hossain; Sagar Lonial; Edmond WALLER
Reconstructing immunity after allogeneic transplantation.
Immunologic research 2004;29(1-3):269-82.
2003: Sagar Lonial
Hematopoietic cytokines: when treating the symptoms does not treat the disease.
Supportive cancer therapy 2003;1(1):36-7.
2003: Cynthia R Giver; Richard O Montes; Stephen Mittelstaedt; Jian-Ming Li; David L Jaye; Sagar Lonial; Michael W Boyer; Edmond WALLER
Ex vivo fludarabine exposure inhibits graft-versus-host activity of allogeneic T cells while preserving graft-versus-leukemia effects.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2003;9(10):616-32.
2003: Sagar Lonial; Edmond WALLER; Jonathan W Simons; Leonard T Heffner
Signal transduction and myeloma: new targets, new hope.
Cancer biology & therapy 2003;2(4):310-9.
2003: Edmond WALLER; Amelia A Langston; Sagar Lonial; Judy Cherry; Jyoti Somani; Andrew J Allen; Hilary Rosenthal; Istvan Redei
Pharmacokinetics and pharmacodynamics of anti-thymocyte globulin in recipients of partially HLA-matched blood hematopoietic progenitor cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2003;9(7):460-71.
2003: Leonard T Heffner; Sagar Lonial
Breakthroughs in the management of multiple myeloma.
Drugs 2003;63(16):1621-36.
2002: Jyoti Somani; Sagar Lonial; Hilary Rosenthal; Suzanne Resnick; Irina Kakhniashvili; Edmond WALLER
A randomized, placebo-controlled trial of subcutaneous administration of GM-CSF as a vaccine adjuvant: effect on cellular and humoral immune responses.
Vaccine 2002;21(3-4):221-30.
2002: Istvan Redei; Amelia A Langston; Sagar Lonial; J K Cherry; A J Allen; E Hamilton; M Jones; V M Bartlett; Edmond WALLER
Rapid hematopoietic engraftment following fractionated TBI conditioning and transplantation with CD34(+) enriched hematopoietic progenitor cells from partially mismatched related donors.
Bone marrow transplantation 2002;30(6):335-40.
2002: Amelia A Langston; Istvan Redei; Angela M Caliendo; Jyoti Somani; Don Hutcherson; Sagar Lonial; Silvana Bucur; Judy Cherry; Andrew Allen; Edmond WALLER
Development of drug-resistant herpes simplex virus infection after haploidentical hematopoietic progenitor cell transplantation.
Blood 2002;99(3):1085-8.
2001: Edmond WALLER; Hilary Rosenthal; T W Jones; Jennifer L Peel; Sagar Lonial; Amelia A Langston; Istvan Redei; I Jurickova; Michael W Boyer
Larger numbers of CD4(bright) dendritic cells in donor bone marrow are associated with increased relapse after allogeneic bone marrow transplantation.
Blood 2001;97(10):2948-56.
2001: Sagar Lonial; C Bomberger; Edmond WALLER
Changes in the pattern of TCR V beta repertoire expression after bone marrow transplant is linked to the HLA haplotype in humans.
British journal of haematology 2001;113(1):224-30.
2000: P S Raju; Sagar Lonial; Y P Gupta; Craig Ziegler
The relationship between market orientation and performance in the hospital industry: a structural equations modeling approach.
Health care management science 2000;3(3):237-47.
2000: Sagar Lonial; T W Jones; Steven M Devine; Elliott F Winton; Leonard T Heffner; K J Smith; Andrew M Yeager; Edmond WALLER
High dose chemotherapy without hematopoietic cell support for the treatment of refractory lymphoma.
Leukemia & lymphoma 2000;36(5-6):497-502.
1999: Sagar Lonial; Paul Alan Bilodeau; Amelia A Langston; C Lewis; S Mossavi-Sai; Jeannine T Holden; Edmond WALLER
Acquired amegakaryocytic thrombocytopenia treated with allogeneic BMT: a case report and review of the literature.
Bone marrow transplantation 1999;24(12):1337-41.
1999: Edmond WALLER; AM Ship; Stephen Mittelstaedt; T W Murray; R Carter; I Kakhniashvili; Sagar Lonial; Jeannine T Holden; Michael W Boyer
Irradiated donor leukocytes promote engraftment of allogeneic bone marrow in major histocompatibility complex mismatched recipients without causing graft-versus-host disease.
Blood 1999;94(9):3222-33.
1997: Sagar Lonial; L Williams; George Carrum; M Ostrowski; P McCarthy
Neosartorya fischeri: an invasive fungal pathogen in an allogeneic bone marrow transplant patient.
Bone marrow transplantation 1997;19(7):753-5.