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Donald Loo

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TOP 3
Xuan Jiang; Donald D F Loo; Bruce A Hirayama; Ernest M Wright
The importance of being aromatic: π interactions in sodium symporters.
Monica Sala-Rabanal; Jeff Abramson; Vincent Chaptal; Bruce A Hirayama; Donald D F Loo; Ernest M Wright
Bridging the gap between structure and kinetics of human SGLT1.
Ernest M Wright; Donald D F Loo; Bruce A Hirayama
Biology of human sodium glucose transporters.

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All Publications

2012: Xuan Jiang; Donald D F Loo; Bruce A Hirayama; Ernest M Wright
The importance of being aromatic: π interactions in sodium symporters.
Biochemistry 2012;51(47):9480-7.
2012: Monica Sala-Rabanal; Jeff Abramson; Vincent Chaptal; Bruce A Hirayama; Donald D F Loo; Ernest M Wright
Bridging the gap between structure and kinetics of human SGLT1.
American journal of physiology. Cell physiology 2012;302(9):C1293-305.
2011: Ernest M Wright; Donald D F Loo; Bruce A Hirayama
Biology of human sodium glucose transporters.
Physiological reviews 2011;91(2):733-94.
2011: Charles S Hummel; Chuan Lu; Donald D F Loo; Bruce A Hirayama; Andrew A Voss; Ernest M Wright
Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.
American journal of physiology. Cell physiology 2011;300(1):C14-21.
2009: Anne-Kristine Meinild; Donald D F Loo; Soren Skovstrup; Ulrik Gether; Nanna MacAulay
Elucidating conformational changes in the gamma-aminobutyric acid transporter-1.
The Journal of biological chemistry 2009;284(24):16226-35.
2008: Monica Sala-Rabanal; Donald D F Loo; Bruce A Hirayama; Ernest M Wright
Molecular mechanism of dipeptide and drug transport by the human renal H+/oligopeptide cotransporter hPEPT2.
American journal of physiology. Renal physiology 2008;294(6):F1422-32.
2008: Donald D F Loo; Bruce A Hirayama; Monica Sala-Rabanal; Ernest M Wright
How drugs interact with transporters: SGLT1 as a model.
The Journal of membrane biology 2008;223(2):87-106.
2007: Bruce A Hirayama; Donald D F Loo; Ana Diez Sampedro; Daisy W Leung; Anne-Kristine Meinild; Mary Lai-Bing; Eric Turk; Ernest M Wright
Sodium-dependent reorganization of the sugar-binding site of SGLT1.
Biochemistry 2007;46(46):13391-406.
2007: Andrew A Voss; Ana Diez Sampedro; Bruce A Hirayama; Donald D F Loo; Ernest M Wright
Imino sugars are potent agonists of the human glucose sensor SGLT3.
Molecular pharmacology 2007;71(2):628-34.
2006: Donald D F Loo; Bruce A Hirayama; Movses H Karakossian; Anne-Kristine Meinild; Ernest M Wright
Conformational dynamics of hSGLT1 during Na+/glucose cotransport.
The Journal of general physiology 2006;128(6):701-20.
2006: Monica Sala-Rabanal; Donald D F Loo; Bruce A Hirayama; Eric Turk; Ernest M Wright
Molecular interactions between dipeptides, drugs and the human intestinal H+ -oligopeptide cotransporter hPEPT1.
The Journal of physiology 2006;574(Pt 1):149-66.
2005: Sepehr Eskandari; Ernest M Wright; Donald D F Loo
Kinetics of the reverse mode of the Na+/glucose cotransporter.
The Journal of membrane biology 2005;204(1):23-32.
2005: Movses H Karakossian; Shelly R Spencer; A Q Gomez; O R Padilla; Ayelet Sacher; Donald D F Loo; Nathan Nelson; Sepehr Eskandari
Novel properties of a mouse gamma-aminobutyric acid transporter (GAT4).
The Journal of membrane biology 2005;203(2):65-82.
2005: Donald D F Loo; Bruce A Hirayama; Albert Cha; Francisco Bezanilla; Ernest M Wright
Perturbation analysis of the voltage-sensitive conformational changes of the Na+/glucose cotransporter.
The Journal of general physiology 2005;125(1):13-36.
2004: Ernest M Wright; Donald D F Loo; Bruce A Hirayama; Eric Turk
Surprising versatility of Na+-glucose cotransporters: SLC5.
Physiology (Bethesda, Md.) 2004;19():370-6.
2004: Ana Diez Sampedro; Donald D F Loo; Ernest M Wright; Guido A Zampighi; Bruce A Hirayama
Coupled sodium/glucose cotransport by SGLT1 requires a negative charge at position 454.
Biochemistry 2004;43(41):13175-84.
2003: Richard D Whitlow; Ayelet Sacher; Donald D F Loo; Nathan Nelson; Sepehr Eskandari
The anticonvulsant valproate increases the turnover rate of gamma-aminobutyric acid transporters.
The Journal of biological chemistry 2003;278(20):17716-26.
2003: Hemanta K Sarkar; Ernest M Wright; Kathryn J Boorer; Donald D F Loo
Electrophysiological properties of the mouse Na+/Cl(-)-dependent taurine transporter (mTauT-1): steady-state kinetics: stoichiometry of taurine transport.
Advances in experimental medicine and biology 2003;526():197-204.
2002: Ayelet Sacher; Nathan Nelson; J T Ogi; E M Wright; Donald D F Loo; Sepehr Eskandari
Presteady-state and steady-state kinetics and turnover rate of the mouse gamma-aminobutyric acid transporter (mGAT3).
The Journal of membrane biology 2002;190(1):57-73.
2002: Donald D F Loo; Ernest M Wright; Thomas Zeuthen
Water pumps.
The Journal of physiology 2002;542(Pt 1):53-60.
2002: Michael H I Shiue; Hovhannes J Gukasyan; Kwang-Jin Kim; Donald D F Loo; Vincent H L Lee
Characterization of cyclic AMP-regulated chloride conductance in the pigmented rabbit conjunctival epithelial cells.
Canadian journal of physiology and pharmacology 2002;80(6):533-40.
2002: Wolf N Fischer; Donald D F Loo; Wolfgang Koch; Uwe Ludewig; Kathryn J Boorer; Mechthild Tegeder; Doris Rentsch; Ernest M Wright; Wolf Frommer
Low and high affinity amino acid H+-cotransporters for cellular import of neutral and charged amino acids.
The Plant journal : for cell and molecular biology 2002;29(6):717-31.
2002: Anne-Kristine Meinild; Bruce A Hirayama; Ernest M Wright; Donald D F Loo
Fluorescence studies of ligand-induced conformational changes of the Na(+)/glucose cotransporter.
Biochemistry 2002;41(4):1250-8.
2002: Sepehr Eskandari; Guido A Zampighi; Daisy W Leung; Ernest M Wright; Donald D F Loo
Inhibition of gap junction hemichannels by chloride channel blockers.
The Journal of membrane biology 2002;185(2):93-102.
2001: Anne-Kristine Meinild; Donald D F Loo; Bruce A Hirayama; E Gallardo; Ernest M Wright
Evidence for the involvement of Ala 166 in coupling Na(+) to sugar transport through the human Na(+)/glucose cotransporter.
Biochemistry 2001;40(39):11897-904.
2001: Thomas Zeuthen; Anne-Kristine Meinild; Donald D F Loo; Ernest M Wright; Dan A Klaerke
Isotonic transport by the Na+-glucose cotransporter SGLT1 from humans and rabbit.
The Journal of physiology 2001;531(Pt 3):631-44.
2001: Matthias Quick; Donald D F Loo; Ernest M Wright
Neutralization of a conserved amino acid residue in the human Na+/glucose transporter (hSGLT1) generates a glucose-gated H+ channel.
The Journal of biological chemistry 2001;276(3):1728-34.
2000: Donald D F Loo; Sepehr Eskandari; Kathryn J Boorer; Hemanta K Sarkar; Ernest M Wright
Role of Cl- in electrogenic Na+-coupled cotransporters GAT1 and SGLT1.
The Journal of biological chemistry 2000;275(48):37414-22.
2000: Daisy W Leung; Donald D F Loo; Bruce A Hirayama; Thomas Zeuthen; Ernest M Wright
Urea transport by cotransporters.
The Journal of physiology 2000;528 Pt 2():251-7.
2000: Anne-Kristine Meinild; Donald D F Loo; Ana M Pajor; Thomas Zeuthen; Ernest M Wright
Water transport by the renal Na(+)-dicarboxylate cotransporter.
American journal of physiology. Renal physiology 2000;278(5):F777-83.
1999: Donald D F Loo; Bruce A Hirayama; Anne-Kristine Meinild; G Chandy; Thomas Zeuthen; Ernest M Wright
Passive water and ion transport by cotransporters.
The Journal of physiology 1999;518 ( Pt 1)():195-202.
1999: Guido A Zampighi; Donald D F Loo; Michael Kreman; Sepehr Eskandari; Ernest M Wright
Functional and morphological correlates of connexin50 expressed in Xenopus laevis oocytes.
The Journal of general physiology 1999;113(4):507-24.
1998: Ernest M Wright; Donald D F Loo; M Panayotova-Heiermann; Bruce A Hirayama; Eric Turk; Sepehr Eskandari; JT Lam
Structure and function of the Na+/glucose cotransporter.
Acta physiologica Scandinavica. Supplementum 1998;643():257-64.
1998: Ana M Pajor; Bruce A Hirayama; Donald D F Loo
Sodium and lithium interactions with the Na+/Dicarboxylate cotransporter.
The Journal of biological chemistry 1998;273(30):18923-9.
1998: M Panayotova-Heiermann; Donald D F Loo; JT Lam; Ernest M Wright
Neutralization of conservative charged transmembrane residues in the Na+/glucose cotransporter SGLT1.
Biochemistry 1998;37(29):10522-8.
1998: Donald D F Loo; Bruce A Hirayama; E M Gallardo; JT Lam; Eric Turk; Ernest M Wright
Conformational changes couple Na+ and glucose transport.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(13):7789-94.
1998: Anne-Kristine Meinild; Dan A Klaerke; Donald D F Loo; Ernest M Wright; Thomas Zeuthen
The human Na+-glucose cotransporter is a molecular water pump.
The Journal of physiology 1998;508 ( Pt 1)():15-21.
1998: B Mackenzie; Donald D F Loo; Ernest M Wright
Relationships between Na+/glucose cotransporter (SGLT1) currents and fluxes.
The Journal of membrane biology 1998;162(2):101-6.
1997: Sepehr Eskandari; Donald D F Loo; G Dai; O Levy; Ernest M Wright; Nancy Carrasco
Thyroid Na+/I- symporter. Mechanism, stoichiometry, and specificity.
The Journal of biological chemistry 1997;272(43):27230-8.
1997: Thomas Zeuthen; Anne-Kristine Meinild; Dan A Klaerke; Donald D F Loo; Ernest M Wright; Bo Belhage; Thomas Litman
Water transport by the Na+/glucose cotransporter under isotonic conditions.
Biology of the cell / under the auspices of the European Cell Biology Organization 1997;89(5-6):307-12.
1997: Bruce A Hirayama; Donald D F Loo; Ernest M Wright
Cation effects on protein conformation and transport in the Na+/glucose cotransporter.
The Journal of biological chemistry 1997;272(4):2110-5.
1997: A Hazama; Donald D F Loo; Ernest M Wright
Presteady-state currents of the rabbit Na+/glucose cotransporter (SGLT1).
The Journal of membrane biology 1997;155(2):175-86.
1997: Ernest M Wright; J R Hirsch; Donald D F Loo; Guido A Zampighi
Regulation of Na+/glucose cotransporters.
The Journal of experimental biology 1997;200(Pt 2):287-93.
1996: B Mackenzie; Donald D F Loo; M Panayotova-Heiermann; Ernest M Wright
Biophysical characteristics of the pig kidney Na+/glucose cotransporter SGLT2 reveal a common mechanism for SGLT1 and SGLT2.
The Journal of biological chemistry 1996;271(51):32678-83.
1996: Donald D F Loo; Thomas Zeuthen; G Chandy; Ernest M Wright
Cotransport of water by the Na+/glucose cotransporter.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(23):13367-70.
1996: Kathryn J Boorer; Donald D F Loo; Wolf Frommer; Ernest M Wright
Transport mechanism of the cloned potato H+/sucrose cotransporter StSUT1.
The Journal of biological chemistry 1996;271(41):25139-44.
1996: Donald D F Loo; J R Hirsch; H K Sarkar; Ernest M Wright
Regulation of the mouse retinal taurine transporter (TAUT) by protein kinases in Xenopus oocytes.
FEBS letters 1996;392(3):250-4.
1996: J R Hirsch; Donald D F Loo; Ernest M Wright
Regulation of Na+/glucose cotransporter expression by protein kinases in Xenopus laevis oocytes.
The Journal of biological chemistry 1996;271(25):14740-6.
1996: Bruce A Hirayama; M P Lostao; M Panayotova-Heiermann; Donald D F Loo; Eric Turk; Ernest M Wright
Kinetic and specificity differences between rat, human, and rabbit Na+-glucose cotransporters (SGLT-1).
The American journal of physiology 1996;270(6 Pt 1):G919-26.
1996: Donald D F Loo; George Sachs; C Prinz
Potassium and chloride currents in rat gastric enterochromaffin-like cells.
The American journal of physiology 1996;270(5 Pt 1):E739-45.
1996: M Panayotova-Heiermann; Donald D F Loo; C T Kong; J E Lever; Ernest M Wright
Sugar binding to Na+/glucose cotransporters is determined by the carboxyl-terminal half of the protein.
The Journal of biological chemistry 1996;271(17):10029-34.
1996: B Mackenzie; Donald D F Loo; Y Fei; W J Liu; Vadivel Ganapathy; F H Leibach; Ernest M Wright
Mechanisms of the human intestinal H+-coupled oligopeptide transporter hPEPT1.
The Journal of biological chemistry 1996;271(10):5430-7.
1996: Kathryn J Boorer; Wolf Frommer; D R Bush; Michael Kreman; Donald D F Loo; Ernest M Wright
Kinetics and specificity of a H+/amino acid transporter from Arabidopsis thaliana.
The Journal of biological chemistry 1996;271(4):2213-20.
1995: M Panayotova-Heiermann; Donald D F Loo; Ernest M Wright
Kinetics of steady-state currents and charge movements associated with the rat Na+/glucose cotransporter.
The Journal of biological chemistry 1995;270(45):27099-105.
1995: Guido A Zampighi; Michael Kreman; Kathryn J Boorer; Donald D F Loo; Francisco Bezanilla; G Chandy; James E Hall; Ernest M Wright
A method for determining the unitary functional capacity of cloned channels and transporters expressed in Xenopus laevis oocytes.
The Journal of membrane biology 1995;148(1):65-78.
1995: K Hager; A Hazama; H Moo Kwon; Donald D F Loo; J S Handler; Ernest M Wright
Kinetics and specificity of the renal Na+/myo-inositol cotransporter expressed in Xenopus oocytes.
The Journal of membrane biology 1995;143(2):103-13.
1994: M P Lostao; Bruce A Hirayama; Donald D F Loo; Ernest M Wright
Phenylglucosides and the Na+/glucose cotransporter (SGLT1): analysis of interactions.
The Journal of membrane biology 1994;142(2):161-70.
1994: Ernest M Wright; Donald D F Loo; M Panayotova-Heiermann; M P Lostao; B H Hirayama; B Mackenzie; Kathryn J Boorer; Guido A Zampighi
'Active' sugar transport in eukaryotes.
The Journal of experimental biology 1994;196():197-212.
1994: B Mackenzie; M Panayotova-Heiermann; Donald D F Loo; J E Lever; Ernest M Wright
SAAT1 is a low affinity Na+/glucose cotransporter and not an amino acid transporter. A reinterpretation.
The Journal of biological chemistry 1994;269(36):22488-91.
1994: Bruce A Hirayama; Donald D F Loo; Ernest M Wright
Protons drive sugar transport through the Na+/glucose cotransporter (SGLT1).
The Journal of biological chemistry 1994;269(34):21407-10.
1994: M Panayotova-Heiermann; Donald D F Loo; M P Lostao; Ernest M Wright
Sodium/D-glucose cotransporter charge movements involve polar residues.
The Journal of biological chemistry 1994;269(33):21016-20.
1994: Kathryn J Boorer; Donald D F Loo; Ernest M Wright
Steady-state and presteady-state kinetics of the H+/hexose cotransporter (STP1) from Arabidopsis thaliana expressed in Xenopus oocytes.
The Journal of biological chemistry 1994;269(32):20417-24.
1994: Ernest M Wright; Donald D F Loo; M Panayotova-Heiermann; Kathryn J Boorer
Mechanisms of Na(+)-glucose cotransport.
Biochemical Society transactions 1994;22(3):646-50.
1994: George Sachs; C Prinz; Donald D F Loo; K Bamberg; M Besancon; Jai Shin
Gastric acid secretion: activation and inhibition.
The Yale journal of biology and medicine 1994;67(3-4):81-95.
1993: B C Hung; Donald D F Loo; Ernest M Wright
Regulation of mouse choroid plexus apical Cl- and K+ channels by serotonin.
Brain research 1993;617(2):285-95.
1993: Donald D F Loo; A Hazama; stéphane supplisson; Eric Turk; Ernest M Wright
Relaxation kinetics of the Na+/glucose cotransporter.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(12):5767-71.
1993: stéphane supplisson; Donald D F Loo; George Sachs
Whole-cell currents in isolated resting Necturus gastric oxynticopeptic cells.
The Journal of physiology 1993;463():57-82.
1993: Ernest M Wright; Bruce A Hirayama; A Hazama; Donald D F Loo; stéphane supplisson; Eric Turk; K M Hager
The sodium/glucose cotransporter (SGLT1).
Society of General Physiologists series 1993;48():229-41.
1992: L Parent; stéphane supplisson; Donald D F Loo; Ernest M Wright
Electrogenic properties of the cloned Na+/glucose cotransporter: I. Voltage-clamp studies.
The Journal of membrane biology 1992;125(1):49-62.
1992: Ernest M Wright; Eric Turk; K Hager; L Lescale-Matys; Bruce A Hirayama; S Supplisson; Donald D F Loo
The Na+/glucose cotransporter (SGLT1).
Acta physiologica Scandinavica. Supplementum 1992;607():201-7.
1992: L Parent; stéphane supplisson; Donald D F Loo; Ernest M Wright
Electrogenic properties of the cloned Na+/glucose cotransporter: II. A transport model under nonrapid equilibrium conditions.
The Journal of membrane biology 1992;125(1):63-79.
1991: stéphane supplisson; Donald D F Loo; George Sachs
Diversity of K+ channels in the basolateral membrane of resting Necturus oxyntic cells.
The Journal of membrane biology 1991;123(3):209-21.
1991: B Birnir; Donald D F Loo; Ernest M Wright
Voltage-clamp studies of the Na+/glucose cotransporter cloned from rabbit small intestine.
Pflügers Archiv : European journal of physiology 1991;418(1-2):79-85.
1990: Emeran Mayer; Donald D F Loo; W J Snape; George Sachs
The activation of calcium and calcium-activated potassium channels in mammalian colonic smooth muscle by substance P.
The Journal of physiology 1990;420():47-71.
1989: Donald D F Loo; Jonathan D Kaunitz
Ca2+ and cAMP activate K+ channels in the basolateral membrane of crypt cells isolated from rabbit distal colon.
The Journal of membrane biology 1989;110(1):19-28.
1988: Donald D F Loo; P D Brown; Ernest M Wright
Ca2+-activated K+ currents in Necturus choroid plexus.
The Journal of membrane biology 1988;105(3):221-31.
1988: P D Brown; Donald D F Loo; Ernest M Wright
Ca2+-activated K+ channels in the apical membrane of Necturus choroid plexus.
The Journal of membrane biology 1988;105(3):207-19.