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Ruth Loos

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Eleanor Wheeler; Inês Barroso; Hannah Blackburn; Elena G Bochukova; Sumedha Garg; Elana Henning; Ni Huang; Matthew E Hurles; Julia M Keogh; Sarah Lindsay; Ruth J F Loos; Stephen O'Rahilly; Nick J Wareham; I Sadaf Farooqi
Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity.
Xiaojing Xu; Xinyan Zhang; Catherine Derom; Xiuhua Ding; Robert Fagard; Marij Gielen; Ruth J F Loos; Harold Snieder; Shaoyong Su; Frank A Treiber; Robert Vlietinck; Xiaoling Wang
Genetic and environmental influences on blood pressure variability: a study in twins.
Karani S Vimaleswaran; Jing Hua Zhao; Frank Dudbridge; Joel N Hirschhorn; Ioanna Tachmazidou; Ruth J F Loos
Candidate genes for obesity-susceptibility show enriched association within a large genome-wide association study for BMI.

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2013: Eleanor Wheeler; Inês Barroso; Hannah Blackburn; Elena G Bochukova; Sumedha Garg; Elana Henning; Ni Huang; Matthew E Hurles; Julia M Keogh; Sarah Lindsay; Ruth J F Loos; Stephen O'Rahilly; Nick J Wareham; I Sadaf Farooqi
Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity.
Nature genetics 2013;45(5):513-7.
2013: Xiaojing Xu; Xinyan Zhang; Catherine Derom; Xiuhua Ding; Robert Fagard; Marij Gielen; Ruth J F Loos; Harold Snieder; Shaoyong Su; Frank A Treiber; Robert Vlietinck; Xiaoling Wang
Genetic and environmental influences on blood pressure variability: a study in twins.
Journal of hypertension 2013;31(4):690-7.
2012: Karani S Vimaleswaran; Jing Hua Zhao; Frank Dudbridge; Joel N Hirschhorn; Ioanna Tachmazidou; Ruth J F Loos
Candidate genes for obesity-susceptibility show enriched association within a large genome-wide association study for BMI.
Human molecular genetics 2012;21(20):4537-42.
2012: Celia G Walker; Gary S Frost; Bruce A Griffin; Susan A Jebb; Ruth J F Loos; Julie A Lovegrove; Adrian P Mander; Thomas A B Sanders; Les J Bluck
Genetic predisposition to type 2 diabetes is associated with impaired insulin secretion but does not modify insulin resistance or secretion in response to an intervention to lower dietary saturated fat.
Genes & nutrition 2012;7(4):529-36.
2012: Karani S Vimaleswaran; Nicholas J Wareham; Lars Ängquist; Heiner Boeing; Nabila Bouatia-Naji; Edith J M Feskens; Rikke D Hansen; Claus Holst; Giovanna Masala; Karina Meidtner; Kim Overvad; Domenico Palli; Wim H M Saris; Thorkild I A Sørensen; Anne Tjønneland; Marianne U Jakobsen; Daphne L van der A; Ruth J F Loos
Association between FTO variant and change in body weight and its interaction with dietary factors: the DiOGenes study.
Obesity (Silver Spring, Md.) 2012;20(8):1669-74.
2012: Adrian E Bauman; Ruth J F Loos; Brian W Martin; Rodrigo S Reis; James F Sallis; Jonathan C Wells
Correlates of physical activity: why are some people physically active and others not?
Lancet 2012;380(9838):258-71.
2012: Eva Fisher; Jytte Halkjaer; Rikke D Hansen; Claus Holst; Ruth J F Loos; Giovanna Masala; Karina Meidtner; Jane Nautrup Ostergaard; Kim Overvad; Domenico Palli; Thorkild Ia Sørensen; Anne Tjønneland; Daphne L van der A; Karani S Vimaleswaran; Nicholas J Wareham; Lars Angquist; Heiner Boeing
Influence of dietary protein intake and glycemic index on the association between TCF7L2 HapA and weight gain.
The American journal of clinical nutrition 2012;95(6):1468-76.
2012: Lesli H Larsen; Thomas M Larsen; Ruth J F Loos; J Alfredo Martinez; Angeliki Papadaki; Andreas F H Pfeiffer; Thorkild Ia Sørensen; Marleen A van Baak; Nathalie Viguerie; Karani S Vimaleswaran; Lars Angquist; Arne Astrup; Jörg Hager; Teodora Handjieva-Darlenska; Claus Holst; Susan A Jebb; Marie Kunesova; Dominique Langin; Wim H M Saris
Analyses of single nucleotide polymorphisms in selected nutrient-sensitive genes in weight-regain prevention: the DIOGENES study.
The American journal of clinical nutrition 2012;95(5):1254-60.
2012: Cathy E Elks; Rebecca Hardy; Diana Kuh; Ruth J F Loos; Nicholas J Wareham; Andrew K Wills; Andrew Wong; Ken K Ong
Adult obesity susceptibility variants are associated with greater childhood weight gain and a faster tempo of growth: the 1946 British Birth Cohort Study.
The American journal of clinical nutrition 2012;95(5):1150-6.
2012: Stephen M Roth; Mark A Sarzynski; Bernd Wolfarth; James M. Hagberg; Ruth J F Loos; Louis Pérusse; Tuomo Rankinen; Claude Bouchard
Advances in exercise, fitness, and performance genomics in 2011.
Medicine and science in sports and exercise 2012;44(5):809-17.
2012: Ruth J F Loos
Genetic determinants of common obesity and their value in prediction.
Best practice & research. Clinical endocrinology & metabolism 2012;26(2):211-26.
2012: Ling Lu; Hongguang Sheng; Jingwen Zhu; Wei Gan; Huaixing Li; Chen Liu; Ruth J F Loos; Xu Lin
Associations between common variants in GC and DHCR7/NADSYN1 and vitamin D concentration in Chinese Hans.
Human genetics 2012;131(3):505-12.
2012: Koenraad Frans Cuypers; Bettina Kulle; Kirsti Kvaløy; Ruth J F Loos; Pål Romundstad; Turid Lingaas Holmen
Obesity-susceptibility loci and their influence on adiposity-related traits in transition from adolescence to adulthood--the HUNT study.
PloS one 2012;7(10):e46912.
2012: Ruth J F Loos; Eric E Schadt
This I believe: gaining new insights through integrating "old" data.
Frontiers in genetics 2012;3():137.
2012: Henri Hooton; Marianne U Jakobsen; Dominique Langin; Ruth J F Loos; Giovanna Masala; Karina Meidtner; Kim Overvad; Domenico Palli; Nina Roswall; Francis Rousseau; Wim H M Saris; Thorkild I A Sørensen; Anne Tjønneland; Daphne L van der A; Karani S Vimaleswaran; Nicolas J Wareham; Lars Angquist; Heiner Boeing; Nabila Bouatia-Naji; Edith J M Feskens; Jorg Hager; Rikke D Hansen; Claus Holst; Karine Clément
Dietary factors impact on the association between CTSS variants and obesity related traits.
PloS one 2012;7(7):e40394.
2012: Cathy E Elks; Ruth J F Loos; Stephen J Sharp; Nicholas J Wareham; Jing Hua Zhao; Marcel den Hoed; Ken K Ong
Variability in the heritability of body mass index: a systematic review and meta-regression.
Frontiers in endocrinology 2012;3():29.
2012: Fuzhong Xue; Zhongshang Yuan; Kay-Tee Khaw; Shengxu Li; Ruth J F Loos; Jian'an Luan; Robert N Luben; Nicholas J Wareham; Jing Hua Zhao
A latent variable partial least squares path modeling approach to regional association and polygenic effect with applications to a human obesity study.
PloS one 2012;7(2):e31927.
2011: Robbert N Touwslager; Robert Vlietinck; Luc J Zimmermann; Catherine Derom; Tom Fowler; Willem-Jan M Gerver; Marij Gielen; Alfons J Houben; Ruth J F Loos; A L M Mulder; Coen D Stehouwer; Maurice Zeegers
Changes in genetic and environmental effects on growth during infancy.
The American journal of clinical nutrition 2011;94(6):1568-74.
2011: John R Speakman; Michael E Symonds; David Allison; Molly S Bray; John C Clapham; Deborah J Clegg; John M de Castro; Abdul G Dulloo; Laurence Gruer; Sally Haw; Johannes Hebebrand; Marion M Hetherington; Susanne Higgs; Susan A Jebb; David A Levitsky; Ruth J F Loos; Simon Luckman; Amy Luke; Vidya Mohammed-Ali; Stephen O'Rahilly; Mark Pereira; Louis Perusse; Tom N Robinson; Barbara Rolls; Margriet S Westerterp-Plantenga
Set points, settling points and some alternative models: theoretical options to understand how genes and environments combine to regulate body adiposity.
Disease models & mechanisms 2011;4(6):733-45.
2011: Ruth J F Loos
The genetic epidemiology of melanocortin 4 receptor variants.
European journal of pharmacology 2011;660(1):156-64.
2011: James M. Hagberg; Tuomo Rankinen; Ruth J F Loos; Louis Pérusse; Stephen M Roth; Bernd Wolfarth; Claude Bouchard
Advances in exercise, fitness, and performance genomics in 2010.
Medicine and science in sports and exercise 2011;43(5):743-52.
2011: Shengxu Li; J H Zhao; Jian'an Luan; C Langenberg; Robert N Luben; Kay-Tee Khaw; Nicholas J Wareham; Ruth J F Loos
Genetic predisposition to obesity leads to increased risk of type 2 diabetes.
Diabetologia 2011;54(4):776-82.
2011: Anders Grøntved; Lars B Andersen; Paul W Franks; Bas Verhage; Nicholas J Wareham; Ulf Ekelund; Ruth J F Loos; Søren Brage
NOS3 variants, physical activity, and blood pressure in the European Youth Heart Study.
American journal of hypertension 2011;24(4):444-50.
2011: Robbert N H Touwslager; Marij Gielen; Catherine Derom; A L M Mulder; Willem-Jan M Gerver; Luc J Zimmermann; Alfons J H M Houben; Coen D A Stehouwer; Robert Francois Vlietinck; Ruth J F Loos; Maurice Zeegers
Determinants of infant growth in four age windows: a twin study.
The Journal of pediatrics 2011;158(4):566-572.e2.
2011: Anne von Ruesten; Anna Floegel; Jytte Halkjaer; Ruth J F Loos; Giovanna Masala; Domenico Palli; Thorkild I A Sørensen; Annika Steffen; Anne Tjønneland; Nicholas J Wareham; Daphne L van der A; Heiner Boeing
Trend in obesity prevalence in European adult cohort populations during follow-up since 1996 and their predictions to 2015.
PloS one 2011;6(11):e27455.
2011: Felix R Day; Ruth J F Loos
Developments in obesity genetics in the era of genome-wide association studies.
Journal of nutrigenetics and nutrigenomics 2011;4(4):222-38.
2011: Hannah S Mumby; Stephen J Sharp; Nicholas J Wareham; Cathy E Elks; Kay-Tee Khaw; Shengxu Li; Ruth J F Loos; Robert N Luben; Ken K Ong
Mendelian Randomisation Study of Childhood BMI and Early Menarche.
Journal of obesity 2011;2011():180729.
2011: Chen Liu; Ruth J F Loos; Ling Lu; Lu Qi; Qibin Qi; Wei Gan; Huaixing Li; Xu Lin
Variants in GLIS3 and CRY2 are associated with type 2 diabetes and impaired fasting glucose in Chinese Hans.
PloS one 2011;6(6):e21464.
2011: Charlotte L Ridgway; Stephen J Sharp; Catherine Derom; Gaston Beunen; Robert Fagard; Robert Francois Vlietinck; Ulf Ekelund; Ruth J F Loos
The contribution of prenatal environment and genetic factors to the association between birth weight and adult grip strength.
PloS one 2011;6(3):e17955.
2011: Huaidong Du; Karani S Vimaleswaran; Lars Angquist; Rikke D Hansen; Daphne L van der A; Claus Holst; Anne Tjønneland; Kim Overvad; Marianne Uhre Jakobsen; Heiner Boeing; Karina Meidtner; Domenico Palli; Giovanna Masala; Nabila Bouatia-Naji; Wim H M Saris; Edith J M Feskens; Nicolas J Wareham; Thorkild I A Sørensen; Ruth J F Loos
Genetic polymorphisms in the hypothalamic pathway in relation to subsequent weight change--the DiOGenes study.
PloS one 2011;6(2):e17436.
2011: Ken K Ong; Cathy E Elks; Andrew Wills; Andrew Wong; Nicholas J Wareham; Ruth J F Loos; Diana Kuh; Rebecca Hardy
Associations between the pubertal timing-related variant in LIN28B and BMI vary across the life course.
The Journal of clinical endocrinology and metabolism 2011;96(1):E125-9.
2011: Chen Liu; Huaixing Li; Qibin Qi; Ling Lu; Wei Gan; Ruth J F Loos; Xu Lin
Common variants in or near FGF5, CYP17A1 and MTHFR genes are associated with blood pressure and hypertension in Chinese Hans.
Journal of hypertension 2011;29(1):70-5.
2011: Valère J Goossens; Steve A deJager; Gert E Grauls; Marij Gielen; Robert Francois Vlietinck; Catherine A Derom; Ruth J F Loos; Sander S Rensen; Wim A Buurman; Jan W Greve; Marleen A van Baak; Petra F Wolffs; Cathrien A Bruggeman; Christian J P A Hoebe
Lack of evidence for the role of human adenovirus-36 in obesity in a European cohort.
Obesity (Silver Spring, Md.) 2011;19(1):220-1.
2010: Marcel den Hoed; Ulf Ekelund; Søren Brage; Anders Grontved; Jing Hua Zhao; Stephen J Sharp; Ken K Ong; Nicholas J Wareham; Ruth J F Loos
Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies.
Diabetes 2010;59(11):2980-8.
2010: Q Qi; Huaixing Li; Ying Wu; Congqiang Liu; Haiping Wu; Zhijie Yu; L Qi; F B Hu; Ruth J F Loos; Xu Lin
Combined effects of 17 common genetic variants on type 2 diabetes risk in a Han Chinese population.
Diabetologia 2010;53(10):2163-6.
2010: Karani S Vimaleswaran; Paul W Franks; Søren Brage; Anders Grontved; Nicholas J Wareham; Ulf Ekelund; Ruth J F Loos
Lack of association between PCK1 polymorphisms and obesity, physical activity, and fitness in European Youth Heart Study (EYHS).
Obesity (Silver Spring, Md.) 2010;18(10):1975-80.
2010: Emanuella De Lucia Rolfe; Ruth J F Loos; Céline Druet; Ronald P Stolk; Ulf Ekelund; Simon J Griffin; Nita G Forouhi; Nicholas J Wareham; Ken K Ong
Association between birth weight and visceral fat in adults.
The American journal of clinical nutrition 2010;92(2):347-52.
2010: K S Vimaleswaran; J H Zhao; N W Wainwright; P G Surtees; Nicholas J Wareham; Ruth J F Loos
Association between serotonin 5-HT-2C receptor gene (HTR2C) polymorphisms and obesity- and mental health-related phenotypes in a large population-based cohort.
International journal of obesity (2005) 2010;34(6):1028-33.
2010: Cathy E Elks; Ruth J F Loos; Stephen J Sharp; Claudia Langenberg; Susan M Ring; Nicholas J Timpson; Andrew R Ness; George Davey Smith; David D Dunger; Nicholas J Wareham; Ken K Ong
Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth.
PLoS medicine 2010;7(5):e1000284.
2010: Marek K Brandys; Annemarie A van Elburg; Ruth J F Loos; Florianne Bauer; Judith Hendriks; Yvonne van der Schouw; Roger A H Adan
Are recently identified genetic variants regulating BMI in the general population associated with anorexia nervosa?
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(2):695-9.
2010: Rebecca Hardy; Andrew Wills; Andrew Wong; Cathy E Elks; Nicholas J Wareham; Ruth J F Loos; Diana Kuh; Ken K Ong
Life course variations in the associations between FTO and MC4R gene variants and body size.
Human molecular genetics 2010;19(3):545-52.
2010: Shengxu Li; Jing Hua Zhao; Jian'an Luan; Ulf Ekelund; Robert N Luben; Kay-Tee Khaw; Nicholas J Wareham; Ruth J F Loos
Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study.
PLoS medicine 2010;7(8):.
2010: Qibin Qi; Huaixing Li; Ruth J F Loos; Chen Liu; Frank B Hu; Hongyu Wu; Zhijie Yu; Xu Lin
Association of PCSK1 rs6234 with obesity and related traits in a Chinese Han population.
PloS one 2010;5(5):e10590.
2010: Chen Liu; Ying Wu; Huaixing Li; Qibin Qi; Claudia Langenberg; Ruth J F Loos; Xu Lin
MTNR1B rs10830963 is associated with fasting plasma glucose, HbA1C and impaired beta-cell function in Chinese Hans from Shanghai.
BMC medical genetics 2010;11():59.
2010: Karani S Vimaleswaran; Ruth J F Loos
Progress in the genetics of common obesity and type 2 diabetes.
Expert reviews in molecular medicine 2010;12():e7.
2010: Shengxu Li; Jing Hua Zhao; Jian'an Luan; Robert N Luben; Sheila A Rodwell; Kay-Tee Khaw; Ken K Ong; Nicholas J Wareham; Ruth J F Loos
Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies.
The American journal of clinical nutrition 2010;91(1):184-90.
2009: Ruth J F Loos
Recent progress in the genetics of common obesity.
British journal of clinical pharmacology 2009;68(6):811-29.
2009: Clara Kelliny; Ulf Ekelund; Lars Bo Andersen; Soren Brage; Ruth J F Loos; Nicholas J Wareham; Claudia Langenberg
Common genetic determinants of glucose homeostasis in healthy children: the European Youth Heart Study.
Diabetes 2009;58(12):2939-45.
2009: Qibin Qi; Huaixing Li; Ruth J F Loos; Chen Liu; Ying Wu; Frank B Hu; Hongyu Wu; Ling Lu; Zhijie Yu; Xu Lin
Common variants in KCNQ1 are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.
Human molecular genetics 2009;18(18):3508-15.
2009: Tuomas Kilpeläinen; Sheila A Bingham; Kay-Tee Khaw; Nicholas J Wareham; Ruth J F Loos
Association of variants in the PCSK1 gene with obesity in the EPIC-Norfolk study.
Human molecular genetics 2009;18(18):3496-501.
2009: N Y Souren; Aimée D C Paulussen; A Steyls; Ruth J F Loos; R D Brandao; Marij Gielen; H J M Smeets; Gaston Beunen; Robert Fagard; Catherine Derom; Robert Francois Vlietinck; Joep P M Geraedts; Maurice Zeegers
Parent-of-origin specific linkage and association of the IGF2 gene region with birth weight and adult metabolic risk factors.
International journal of obesity (2005) 2009;33(9):962-70.
2009: Stephanie-May Ruchat; Cathy E Elks; Ruth J F Loos; Marie-Claude Vohl; S John Weisnagel; Tuomo Rankinen; Claude Bouchard; Louis Pérusse
Association between insulin secretion, insulin sensitivity and type 2 diabetes susceptibility variants identified in genome-wide association studies.
Acta diabetologica 2009;46(3):217-26.
2009: Karani S Vimaleswaran; Shengxu Li; Jing Hua Zhao; Jian'an Luan; Sheila A Bingham; Kay-Tee Khaw; Ulf Ekelund; Nicholas J Wareham; Ruth J F Loos
Physical activity attenuates the body mass index-increasing influence of genetic variation in the FTO gene.
The American journal of clinical nutrition 2009;90(2):425-8.
2009: C Langenberg; L Pascoe; A Mari; A Tura; M Laakso; T M Frayling; I Barroso; Ruth J F Loos; Nicholas J Wareham; M Walker
Common genetic variation in the melatonin receptor 1B gene (MTNR1B) is associated with decreased early-phase insulin response.
Diabetologia 2009;52(8):1537-42.
2009: Ying Wu; Huaixing Li; Ruth J F Loos; Qibin Qi; Frank B Hu; Yong Liu; Xu Lin
RBP4 variants are significantly associated with plasma RBP4 levels and hypertriglyceridemia risk in Chinese Hans.
Journal of lipid research 2009;50(7):1479-86.
2009: Karani S Vimaleswaran; Paul W Franks; Søren Brage; Luis B Sardinha; Lars B Andersen; Nicholas J Wareham; Ulf Ekelund; Ruth J F Loos
Absence of association between the INSIG2 gene polymorphism (rs7566605) and obesity in the European Youth Heart Study (EYHS).
Obesity (Silver Spring, Md.) 2009;17(7):1453-7.
2009: Ruth J F Loos; David B Savage
Inherited susceptibility to non-alcoholic fatty liver disease.
Diabetologia 2009;52(6):1000-2.
2009: Q Qi; Ying Wu; Huaixing Li; Ruth J F Loos; F B Hu; L Sun; Ling Lu; An Pan; Congqiang Liu; H Wu; Liang Chen; Zhijie Yu; Xu Lin
Association of GCKR rs780094, alone or in combination with GCK rs1799884, with type 2 diabetes and related traits in a Han Chinese population.
Diabetologia 2009;52(5):834-43.
2009: E C Brito; Karani Santhanakrishnan Vimaleswaran; Søren Brage; L B Andersen; L B Sardinha; Nicholas J Wareham; Ulf Ekelund; Ruth J F Loos; Paul W Franks
PPARGC1A sequence variation and cardiovascular risk-factor levels: a study of the main genetic effects and gene x environment interactions in children from the European Youth Heart Study.
Diabetologia 2009;52(4):609-13.
2009: Stephanie-May Ruchat; Cathy E Elks; Ruth J F Loos; Marie-Claude Vohl; S John Weisnagel; Tuomo Rankinen; Claude Bouchard; Louis Pérusse
Evidence of interaction between type 2 diabetes susceptibility genes and dietary fat intake for adiposity and glucose homeostasis-related phenotypes.
Journal of nutrigenetics and nutrigenomics 2009;2(4-5):225-34.
2008: Nicholas J Wareham; Elizabeth H Young; Ruth J F Loos
Epidemiological study designs to investigate gene-behavior interactions in the context of human obesity.
Obesity (Silver Spring, Md.) 2008;16 Suppl 3():S66-71.
2008: Nicole Y Souren; Maurice Zeegers; Rob G J H Janssen; Anja Steyls; Marij Gielen; Ruth J F Loos; Gaston Beunen; Robert Fagard; Alphons P M Stassen; Jeroen Aerssens; Catherine Derom; Robert Francois Vlietinck; Aimee D C Paulussen
Anthropometry, carbohydrate and lipid metabolism in the East Flanders Prospective Twin Survey: linkage of candidate genes using two sib-pair based variance components analyses.
Twin research and human genetics : the official journal of the International Society for Twin Studies 2008;11(5):505-16.
2008: Ying Wu; Huaixing Li; Ruth J F Loos; Zhijie Yu; Xingwang Ye; Lihua Chen; An Pan; Frank B Hu; Xu Lin
Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.
Diabetes 2008;57(10):2834-42.
2008: Karani Santhanakrishnan Vimaleswaran; Jian'an Luan; Gitte Andersen; Y Li Muller; Eleanor Wheeler; Ema C Brito; Stephen O'Rahilly; Oluf Pedersen; Leslie J Baier; William C Knowler; Inês Barroso; Nicholas J Wareham; Ruth J F Loos; Paul W Franks
The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals.
Journal of applied physiology (Bethesda, Md. : 1985) 2008;105(4):1352-8.
2008: Katherine A Fawcett; Neil Grimsey; Ruth J F Loos; Eleanor Wheeler; Allan Daly; Maria A Soos; Robert K Semple; Holly Syddall; Cyrus Cooper; Symeon Siniossoglou; Stephen O'Rahilly; Nicholas J Wareham; Inês Barroso
Evaluating the role of LPIN1 variation in insulin resistance, body weight, and human lipodystrophy in U.K. Populations.
Diabetes 2008;57(9):2527-33.
2008: Maarten W Peeters; Martine Thomis; Ruth J F Loos; Catherine Derom; Robert Fagard; Robert Francois Vlietinck; Gaston Beunen
Clustering of metabolic risk factors in young adults: genes and environment.
Atherosclerosis 2008;200(1):168-76.
2008: N Y Souren; Aimée D C Paulussen; A Steyls; Ruth J F Loos; A P Stassen; Marij Gielen; H J M Smeets; Gaston Beunen; Robert Fagard; Catherine Derom; Robert Francois Vlietinck; Joep P M Geraedts; Maurice Zeegers
Common SNPs in LEP and LEPR associated with birth weight and type 2 diabetes-related metabolic risk factors in twins.
International journal of obesity (2005) 2008;32(8):1233-9.
2008: Shengxu Li; Ruth J F Loos
Progress in the genetics of common obesity: size matters.
Current opinion in lipidology 2008;19(2):113-21.
2008: Marij Gielen; Patrick J Lindsey; Catherine Derom; Ruth J F Loos; Nicole Y Souren; Aimee D C Paulussen; Maurice Zeegers; Robert Derom; Robert Francois Vlietinck; Jan G Nijhuis
Twin-specific intrauterine 'growth' charts based on cross-sectional birthweight data.
Twin research and human genetics : the official journal of the International Society for Twin Studies 2008;11(2):224-35.
2008: Karani S Vimaleswaran; Paul W Franks; Inês Barroso; Soren Brage; Ulf Ekelund; Nicholas J Wareham; Ruth J F Loos
Habitual energy expenditure modifies the association between NOS3 gene polymorphisms and blood pressure.
American journal of hypertension 2008;21(3):297-302.
2008: Manjinder S Sandhu; Dawn M Waterworth; Sally L Debenham; Eleanor Wheeler; Konstantinos Papadakis; Jing Hua Zhao; Kijoung Song; Xin Yuan; Toby Johnson; Sofie Ashford; Michael Inouye; Robert Luben; Matthew Sims; David Hadley; Wendy L McArdle; Philip Barter; Y Antero Kesäniemi; Robert W Mahley; Ruth McPherson; Scott M Grundy; Sheila A Bingham; Kay-Tee Khaw; Ruth J F Loos; Gérard Waeber; Inês Barroso; David P Strachan; Panos Deloukas; Peter Vollenweider; Nicholas J Wareham; Vincent Mooser
LDL-cholesterol concentrations: a genome-wide association study.
Lancet 2008;371(9611):483-91.
2008: Huaixing Li; Ying Wu; Ruth J F Loos; Frank B Hu; Yong Liu; Jing Wang; Zhijie Yu; Xu Lin
Variants in the fat mass- and obesity-associated (FTO) gene are not associated with obesity in a Chinese Han population.
Diabetes 2008;57(1):264-8.
2007: Ruth J F Loos; Tuomo Rankinen; Louis Pérusse; Angelo Tremblay; Jean-Pierre Després; Claude Bouchard
Association of lipin 1 gene polymorphisms with measures of energy and glucose metabolism.
Obesity (Silver Spring, Md.) 2007;15(11):2723-32.
2007: N Y Souren; Aimée D C Paulussen; Ruth J F Loos; Marij Gielen; Gaston Beunen; Robert Fagard; Catherine Derom; Robert Francois Vlietinck; Maurice Zeegers
Anthropometry, carbohydrate and lipid metabolism in the East Flanders Prospective Twin Survey: heritabilities.
Diabetologia 2007;50(10):2107-16.
2007: Maarten W Peeters; Gaston Beunen; Hermine Maes; Ruth J F Loos; Albrecht L Claessens; Robert Francois Vlietinck; Martine Thomis
Genetic and environmental determination of tracking in subcutaneous fat distribution during adolescence.
The American journal of clinical nutrition 2007;86(3):652-60.
2007: Maarten W Peeters; Martine Thomis; Ruth J F Loos; Catherine Derom; R Fagard; Albrecht L Claessens; Robert Francois Vlietinck; Gaston Beunen
Heritability of somatotype components: a multivariate analysis.
International journal of obesity (2005) 2007;31(8):1295-301.
2007: Ruth J F Loos; Paul W Franks; Richard W Francis; Inês Barroso; Fiona M Gribble; David B Savage; Ken K Ong; Stephen O'Rahilly; Nicholas J Wareham
TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population.
Diabetes 2007;56(7):1943-7.
2007: Paul W Franks; Ruth J F Loos; Søren Brage; Stephen O'Rahilly; Nicholas J Wareham; Ulf Ekelund
Physical activity energy expenditure may mediate the relationship between plasma leptin levels and worsening insulin resistance independently of adiposity.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;102(5):1921-6.
2007: José L Mesa; Ruth J F Loos; Paul W Franks; Ken K Ong; Jian'an Luan; Stephen O'Rahilly; Nicholas J Wareham; Inês Barroso
Lamin A/C polymorphisms, type 2 diabetes, and the metabolic syndrome: case-control and quantitative trait studies.
Diabetes 2007;56(3):884-9.
2007: Ruth J F Loos; Inês Barroso; Stephen O'Rahilly; Nicholas J Wareham
Comment on "A common genetic variant is associated with adult and childhood obesity".
Science (New York, N.Y.) 2007;315(5809):187; author reply 187.
2007: Marij Gielen; Patrick J Lindsey; Catherine Derom; Ruth J F Loos; Robert Derom; Jan G Nijhuis; Robert Francois Vlietinck
Twin birth weight standards.
Neonatology 2007;92(3):164-73.
2007: Ruth J F Loos; Stéphanie Ruchat; Tuomo Rankinen; Angelo Tremblay; Louis Pérusse; Claude Bouchard
Adiponectin and adiponectin receptor gene variants in relation to resting metabolic rate, respiratory quotient, and adiposity-related phenotypes in the Quebec Family Study.
The American journal of clinical nutrition 2007;85(1):26-34.
2006: Marij Gielen; Patrick J Lindsey; Catherine Derom; Ruth J F Loos; Robert Derom; Jan G Nijhuis; Robert Francois Vlietinck
Curves of placental weights of live-born twins.
Twin research and human genetics : the official journal of the International Society for Twin Studies 2006;9(5):664-72.
2006: Paul W Franks; Ruth J F Loos
PGC-1alpha gene and physical activity in type 2 diabetes mellitus.
Exercise and sport sciences reviews 2006;34(4):171-5.
2006: Ken K Ong; Ruth J F Loos
Rapid infancy weight gain and subsequent obesity: systematic reviews and hopeful suggestions.
Acta paediatrica (Oslo, Norway : 1992) 2006;95(8):904-8.
2006: Ruth J F Loos; Tuomo Rankinen; Yvon C Chagnon; Angelo Tremblay; Louis Pérusse; Claude Bouchard
Polymorphisms in the leptin and leptin receptor genes in relation to resting metabolic rate and respiratory quotient in the Québec Family Study.
International journal of obesity (2005) 2006;30(1):183-90.
2005: Ruth J F Loos; Tuomo Rankinen; Treva Rice; Dabeeru C Rao; Arthur S Leon; James Skinner; Claude Bouchard; George Argyropoulos
Two ethnic-specific polymorphisms in the human Agouti-related protein gene are associated with macronutrient intake.
The American journal of clinical nutrition 2005;82(5):1097-101.
2005: Maarten W Peeters; Martine Thomis; Hermine Maes; Gaston Beunen; Ruth J F Loos; Albrecht L Claessens; Robert Francois Vlietinck
Genetic and environmental determination of tracking in static strength during adolescence.
Journal of applied physiology (Bethesda, Md. : 1985) 2005;99(4):1317-26.
2005: Nicola Santoro; Tuomo Rankinen; Louis Pérusse; Ruth J F Loos; Claude Bouchard
MC4R marker associated with stature in children and young adults: a longitudinal study.
Journal of pediatric endocrinology & metabolism : JPEM 2005;18(9):859-63.
2005: Maarten W Peeters; Martine Thomis; Hermine Maes; Ruth J F Loos; Albrecht L Claessens; Robert Francois Vlietinck; Gaston Beunen
Genetic and environmental causes of tracking in explosive strength during adolescence.
Behavior genetics 2005;35(5):551-63.
2005: Marij Gielen; Sara-Joan Pinto-Sietsma; Maurice Zeegers; Ruth J F Loos; Robert Fagard; Peter W de Leeuw; Gaston Beunen; Catherine Derom; Robert Francois Vlietinck
Birth weight and creatinine clearance in young adult twins: influence of genetic, prenatal, and maternal factors.
Journal of the American Society of Nephrology : JASN 2005;16(8):2471-6.
2005: Ruth J F Loos; Tuomo Rankinen
Gene-diet interactions on body weight changes.
Journal of the American Dietetic Association 2005;105(5 Suppl 1):S29-34.
2005: Ruth J F Loos; Tuomo Rankinen; Angelo Tremblay; Louis Pérusse; Yvon C Chagnon; Claude Bouchard
Melanocortin-4 receptor gene and physical activity in the Québec Family Study.
International journal of obesity (2005) 2005;29(4):420-8.
2005: Robert Derom; Catherine Derom; Ruth J F Loos; evert thiery; Robert Francois Vlietinck; Jean-Pierre Fryns
Gender mix: does it modify birthweight--outcome association?
Paediatric and perinatal epidemiology 2005;19 Suppl 1():37-40.
2005: Ruth J F Loos; Catherine Derom; Robert Derom; Robert Francois Vlietinck
Determinants of birthweight and intrauterine growth in liveborn twins.
Paediatric and perinatal epidemiology 2005;19 Suppl 1():15-22.
2004: Christina A Geithner; Martine Thomis; Bavo Vanden Eynde; Hermine Maes; Ruth J F Loos; Maarten Peeters; Albrecht L Claessens; Robert Francois Vlietinck; Robert M Malina; Gaston Beunen
Growth in peak aerobic power during adolescence.
Medicine and science in sports and exercise 2004;36(9):1616-24.
2004: Ruth J F Loos; Tuomo Rankinen; Arthur S Leon; James Skinner; Jack H Wilmore; D C Rao; Claude Bouchard
Calcium intake is associated with adiposity in Black and White men and White women of the HERITAGE Family Study.
The Journal of nutrition 2004;134(7):1772-8.
2003: Ruth J F Loos; Peter T Katzmarzyk; Dabeeru C Rao; Treva Rice; Arthur S Leon; James Skinner; Jack H Wilmore; Tuomo Rankinen; Claude Bouchard
Genome-wide linkage scan for the metabolic syndrome in the HERITAGE Family Study.
The Journal of clinical endocrinology and metabolism 2003;88(12):5935-43.
2003: Ruth J F Loos; Claude Bouchard
Obesity--is it a genetic disorder?
Journal of internal medicine 2003;254(5):401-25.
2003: Maarten W Peeters; Martine Thomis; Albrecht L Claessens; Ruth J F Loos; Hermine Maes; Roeland Lysens; Bavo Vanden Eynde; Robert Francois Vlietinck; Gaston Beunen
Heritability of somatotype components from early adolescence into young adulthood: a multivariate analysis on a longitudinal twin study.
Annals of human biology 2003;30(4):402-18.
2003: Ruth J F Loos; Johan Verhaeghe; Francis de Zegher; Gaston Beunen; Catherine Derom; Robert Fagard; Chantal Mathieu; Robert Francois Vlietinck
Markers for cardiovascular disease in monozygotic twins discordant for the use of third-generation oral contraceptives.
Journal of human hypertension 2003;17(7):481-5.
2003: Robert H Fagard; Ruth J F Loos; Gaston Beunen; Catherine Derom; Robert Francois Vlietinck
Influence of chorionicity on the heritability estimates of blood pressure: a study in twins.
Journal of hypertension 2003;21(7):1313-8.
2003: Albrecht L Claessens; Jan Bourgois; Gaston Beunen; Renaat Philippaerts; Martine Thomis; Johan Lefevre; Ruth J F Loos; Jacques Vrijens
Age at menarche in relation to anthropometric characteristics, competition level and boat category in elite junior rowers.
Annals of human biology 2003;30(2):148-59.
2003: Catherine Derom; Robert Derom; Ruth J F Loos; Nele Jacobs; Robert Francois Vlietinck
Retrospective determination of chorion type in twins using a simple questionnaire.
Twin research : the official journal of the International Society for Twin Studies 2003;6(1):19-21.
2002: Ruth J F Loos; David I W Phillips; Robert Fagard; Gaston Beunen; Catherine Derom; Chantal Mathieu; Johan Verhaeghe; Robert Francois Vlietinck
The influence of maternal BMI and age in twin pregnancies on insulin resistance in the offspring.
Diabetes care 2002;25(12):2191-6.
2002: Ruth J F Loos; Gaston Beunen; Robert Fagard; Catherine Derom; Robert Francois Vlietinck
Birth weight and body composition in young women: a prospective twin study.
The American journal of clinical nutrition 2002;75(4):676-82.
2001: Ruth J F Loos; Gaston Beunen; Robert Fagard; Catherine Derom; Robert Francois Vlietinck
The influence of zygosity and chorion type on fat distribution in young adult twins consequences for twin studies.
Twin research : the official journal of the International Society for Twin Studies 2001;4(5):356-64.
2001: Ruth J F Loos; Gaston Beunen; Robert Fagard; Catherine Derom; Robert Francois Vlietinck
Birth weight and body composition in young adult men--a prospective twin study.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2001;25(10):1537-45.
2001: Ruth J F Loos; Catherine Derom; Robert Derom; Robert Francois Vlietinck
Birthweight in liveborn twins: the influence of the umbilical cord insertion and fusion of placentas.
BJOG : an international journal of obstetrics and gynaecology 2001;108(9):943-8.
2001: Ruth J F Loos; Catherine Derom; R Eeckels; Robert Derom; Robert Francois Vlietinck
Length of gestation and birthweight in dizygotic twins.
Lancet 2001;358(9281):560-1.
2001: R Bustami; Emmanuel Lesaffre; Geert Molenberghs; Ruth J F Loos; M Danckaerts; Robert Francois Vlietinck
Modelling bivariate ordinal responses smoothly with examples from ophthalmology and genetics.
Statistics in medicine 2001;20(12):1825-42.
2001: Wouter J Vinck; Robert H Fagard; Ruth J F Loos; Robert Francois Vlietinck
The impact of genetic and environmental influences on blood pressure variance across age-groups.
Journal of hypertension 2001;19(6):1007-13.
2000: Gaston Beunen; Martine Thomis; Hermine Maes; Ruth J F Loos; Robert M Malina; Albrecht L Claessens; Robert Francois Vlietinck
Genetic variance of adolescent growth in stature.
Annals of human biology 2000;27(2):173-86.
1998: Ruth J F Loos; Catherine Derom; Robert Francois Vlietinck; Robert Derom
The East Flanders Prospective Twin Survey (Belgium): a population-based register.
Twin research : the official journal of the International Society for Twin Studies 1998;1(4):167-75.
1998: Gaston Beunen; Hermine Maes; Robert Francois Vlietinck; R M Malina; Martine Thomis; E Feys; Ruth J F Loos; Catherine Derom
Univariate and multivariate genetic analysis of subcutaneous fatness and fat distribution in early adolescence.
Behavior genetics 1998;28(4):279-88.
1997: B Pelsmaekers; Ruth J F Loos; Carine Carels; Catherine Derom; Robert Francois Vlietinck
The genetic contribution to dental maturation.
Journal of dental research 1997;76(7):1337-40.
1997: Ruth J F Loos; Martine Thomis; Hermine Maes; Gaston Beunen; Albrecht L Claessens; Catherine Derom; E Legius; Robert Derom; Robert Francois Vlietinck
Gender-specific regional changes in genetic structure of muscularity in early adolescence.
Journal of applied physiology (Bethesda, Md. : 1985) 1997;82(6):1802-10.
1996: Johan Verhaeghe; Ruth J F Loos; Robert Francois Vlietinck; E V Herck; Rita van Bree; A M Schutter
C-peptide, insulin-like growth factors I and II, and insulin-like growth factor binding protein-1 in cord serum of twins: genetic versus environmental regulation.
American journal of obstetrics and gynecology 1996;175(5):1180-8.
1996: Catherine Derom; evert thiery; Robert Francois Vlietinck; Ruth J F Loos; Robert Derom
Handedness in twins according to zygosity and chorion type: a preliminary report.
Behavior genetics 1996;26(4):407-8.