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Pilar Barrera

Research Profile

Disorders

Rheumatoid Arthritis

Chemicals & Drugs

Physiology

Anatomy

Concepts & Ideas

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Publications

TOP 3
Laëtitia Michou; Paola Migliorini; Elisabeth Petit-Teixeira; Leo van de Putte; René Westhovens; Helena Alves; Alejandro Balsa; Thomas Bardin; Pilar Barrera; Stefano Bombardieri; François Cornélis; Jean-Michel Levesque; Maria J G Fernandes
A genetic association study of the CLEC12A gene in rheumatoid arthritis.
Jaap Fransen; Henk-Jan Guchelaar; Tom W J Huizinga; Wouter M Kooloos; Piet L C M van Riel; Judith A M Wessels; Pilar Barrera
Clinical pharmacogenetic model to predict response of MTX monotherapy in patients with established rheumatoid arthritis after DMARD failure.
Erik J M Toonen; Simon V van Reijmersdal; Piet L C M van Riel; Joris A Veltman; Alfons A den Broeder; A M M Eijsbouts; Barbara Franke; Christian Gilissen; W Kievit; Timothy R D J Radstake; Hans Scheffer; Pilar Barrera; Marieke Coenen
Validation study of existing gene expression signatures for anti-TNF treatment in patients with rheumatoid arthritis.

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All Publications

2012: Laëtitia Michou; Paola Migliorini; Elisabeth Petit-Teixeira; Leo van de Putte; René Westhovens; Helena Alves; Alejandro Balsa; Thomas Bardin; Pilar Barrera; Stefano Bombardieri; François Cornélis; Jean-Michel Levesque; Maria J G Fernandes
A genetic association study of the CLEC12A gene in rheumatoid arthritis.
Joint, bone, spine : revue du rhumatisme 2012;79(5):451-6.
2012: Jaap Fransen; Henk-Jan Guchelaar; Tom W J Huizinga; Wouter M Kooloos; Piet L C M van Riel; Judith A M Wessels; Pilar Barrera
Clinical pharmacogenetic model to predict response of MTX monotherapy in patients with established rheumatoid arthritis after DMARD failure.
Pharmacogenomics 2012;13(9):1087-94.
2012: Erik J M Toonen; Simon V van Reijmersdal; Piet L C M van Riel; Joris A Veltman; Alfons A den Broeder; A M M Eijsbouts; Barbara Franke; Christian Gilissen; W Kievit; Timothy R D J Radstake; Hans Scheffer; Pilar Barrera; Marieke Coenen
Validation study of existing gene expression signatures for anti-TNF treatment in patients with rheumatoid arthritis.
PloS one 2012;7(3):e33199.
2011: Karen Dawidowicz; Yannick Allanore; Mickael Guedj; Céline Pierlot; Stefano Bombardieri; Alejandro Balsa; René Westhovens; Pilar Barrera; Helena Alves; Vitor Hugo Teixeira; Elisabeth Petit-Teixeira; Leo van de Putte; Piet van Riel; Bernard Prum; Thomas Bardin; Olivier Meyer; François Cornélis; Philippe Dieudé
The interferon regulatory factor 5 gene confers susceptibility to rheumatoid arthritis and influences its erosive phenotype.
Annals of the rheumatic diseases 2011;70(1):117-21.
2010: Marieke Coenen; Christian Enevold; Pilar Barrera; Mascha M V A P Schijvenaars; Erik J M Toonen; Hans Scheffer; Leonid Padyukov; Alf Kastbom; Lars Klareskog; Anne Barton; W Kievit; Maarten J Rood; Tim L Jansen; Dorine W Swinkels; Piet L C M van Riel; Barbara Franke; Klaus Bendtzen; Timothy R D J Radstake
Genetic variants in toll-like receptors are not associated with rheumatoid arthritis susceptibility or anti-tumour necrosis factor treatment outcome.
PloS one 2010;5(12):e14326.
2009: Marieke Coenen; Gosia Trynka; Sandra Heskamp; Barbara Franke; Cleo C van Diemen; Joanna Smolonska; Miek van Leeuwen; Elisabeth Brouwer; Marike H Boezen; Dirkje S Postma; Mathieu Platteel; Pieter Zanen; Jan-Willem W J Lammers; Harry J M Groen; Willem P T M Mali; Chris J Mulder; Greetje J Tack; Wieke H M Verbeek; Victorien M Wolters; Roderick H J Houwen; M Luisa Mearin; David A van Heel; Timothy R D J Radstake; Piet L C M van Riel; Cisca Wijmenga; Pilar Barrera; Alexandra Zhernakova
Common and different genetic background for rheumatoid arthritis and coeliac disease.
Human molecular genetics 2009;18(21):4195-203.
2009: Jana Burkhardt; Elisabeth Petit-Teixeira; Vitor Hugo Teixeira; Holger Kirsten; Sophie Garnier; Sandra Ruehle; Christian Oeser; Grit Wolfram; Markus Scholz; Paola Migliorini; Alejandro Balsa; René Westhovens; Pilar Barrera; Helena Alves; Dora Pascual-Salcedo; Stefano Bombardieri; Jan Dequeker; Timothy R Radstake; Piet Van Riel; Leo van de Putte; Thomas Bardin; Bernard Prum; Ulrike Buchegger-Podbielski; Frank Emmrich; Inga Melchers; François Cornelis; Peter Ahnert
Association of the X-chromosomal genes TIMP1 and IL9R with rheumatoid arthritis.
The Journal of rheumatology 2009;36(10):2149-57.
2009: Lydia G Schipper; Jaap Fransen; Pilar Barrera; Alfons A den Broeder; P L C M van Riel
Methotrexate therapy in rheumatoid arthritis after failure to sulphasalazine: to switch or to add?
Rheumatology (Oxford, England) 2009;48(10):1247-53.
2009: Mieke F Roelofs; Mark Wenink; F Brentano; Shahla Abdollahi-Roodsaz; Birgitte Oppers-Walgreen; Pilar Barrera; P L C M van Riel; Leo A B Joosten; D Kyburz; Wim B van den Berg; T R D J Radstake
Type I interferons might form the link between Toll-like receptor (TLR) 3/7 and TLR4-mediated synovial inflammation in rheumatoid arthritis (RA).
Annals of the rheumatic diseases 2009;68(9):1486-93.
2009: Lydia G Schipper; Jaap Fransen; Pilar Barrera; Piet L C M Van Riel
Methotrexate in combination with sulfasalazine is more effective in rheumatoid arthritis patients who failed sulfasalazine than in patients naive to both drugs.
Rheumatology (Oxford, England) 2009;48(7):828-33.
2009: Calin Popa; Pilar Barrera; Leo A B Joosten; Piet L C M van Riel; Bart Jan Kullberg; Jos W M van der Meer; Mihai G Netea
Cytokine production from stimulated whole blood cultures in rheumatoid arthritis patients treated with various TNF blocking agents.
European cytokine network 2009;20(2):88-93.
2009: Calin Popa; Lambertus J H Van Tits; Pilar Barrera; H L M Lemmers; F H J van den Hoogen; P L C M van Riel; T R D J Radstake; Mihai G Netea; M Roest; Anton F H Stalenhoef
Anti-inflammatory therapy with tumour necrosis factor alpha inhibitors improves high-density lipoprotein cholesterol antioxidative capacity in rheumatoid arthritis patients.
Annals of the rheumatic diseases 2009;68(6):868-72.
2009: Calin Popa; Mihai G Netea; Jacqueline de Graaf; F H J van den Hoogen; Timothy R D J Radstake; Helga Toenhake-Dijkstra; Piet L C M van Riel; Jos W M van der Meer; Anton F H Stalenhoef; Pilar Barrera
Circulating leptin and adiponectin concentrations during tumor necrosis factor blockade in patients with active rheumatoid arthritis.
The Journal of rheumatology 2009;36(4):724-30.
2009: Vitor Hugo Teixeira; Celine Pierlot; Paola Migliorini; Alejandro Balsa; René Westhovens; Pilar Barrera; Helena Alves; Carlos Vaz; Manuela Fernandes; Dora Pascual-Salcedo; Stefano Bombardieri; Jan Dequeker; Timothy R Radstake; Piet Van Riel; Leo van de Putte; Antonio Lopes-Vaz; Thomas Bardin; Bernard Prum; François Cornélis; Elisabeth Petit-Teixeira
Testing for the association of the KIAA1109/Tenr/IL2/IL21 gene region with rheumatoid arthritis in a European family-based study.
Arthritis research & therapy 2009;11(2):R45.
2008: Erik J M Toonen; Pilar Barrera; T R D J Radstake; P L C M van Riel; Hans Scheffer; B Franke; Marieke Coenen
Gene expression profiling in rheumatoid arthritis: current concepts and future directions.
Annals of the rheumatic diseases 2008;67(12):1663-9.
2008: Frank A D T G Wagener; Erik J M Toonen; Lonneke Wigman; Jaap Fransen; M C W Creemers; Timothy R D J Radstake; Marieke Coenen; Pilar Barrera; Piet L C M van Riel; Frans G M Russel
HMOX1 promoter polymorphism modulates the relationship between disease activity and joint damage in rheumatoid arthritis.
Arthritis and rheumatism 2008;58(11):3388-93.
2008: Fina A S Kurreeman; D Rocha; Jeanine J Houwing-Duistermaat; S Vrijmoet; V H Teixeira; P Migliorini; A Balsa; R Westhovens; Pilar Barrera; Helena Alves; C Vaz; M Fernandes; D Pascual-Salcedo; L Michou; S Bombardieri; Timothy Radstake; P van Riel; L van de Putte; A Lopes-Vaz; B Prum; T Bardin; Ivo Gut; F Cornelis; Tom W J Huizinga; E Petit-Teixeira; René E M Toes
Replication of the tumor necrosis factor receptor-associated factor 1/complement component 5 region as a susceptibility locus for rheumatoid arthritis in a European family-based study.
Arthritis and rheumatism 2008;58(9):2670-4.
2008: Erik J M Toonen; Marieke Coenen; W Kievit; Jaap Fransen; A M M Eijsbouts; Hans Scheffer; Timothy Radstake; M C W Creemers; D-J R A M de Rooij; P L C M van Riel; B Franke; Pilar Barrera
The tumour necrosis factor receptor superfamily member 1b 676T>G polymorphism in relation to response to infliximab and adalimumab treatment and disease severity in rheumatoid arthritis.
Annals of the rheumatic diseases 2008;67(8):1174-7.
2008: Gisela Orozco; Behrooz Alizadeh; Angelica Maria Delgado-Vega; Miguel A González-Gay; Alejandro Balsa; Dora Pascual-Salcedo; Benjamín Fernández-Gutierrez; María Francisca González-Escribano; Ingemar F Petersson; Piet L C M van Riel; Pilar Barrera; Marieke Coenen; Timothy Radstake; Miek A van Leeuwen; Cisca Wijmenga; Bobby P C Koeleman; Marta E Alarcón-Riquelme; Javier Martín
Association of STAT4 with rheumatoid arthritis: a replication study in three European populations.
Arthritis and rheumatism 2008;58(7):1974-80.
2007: E H J G Aarntzen; Pilar Barrera
Short digits...what's up?
Arthritis and rheumatism 2007;57(8):1568-71.
2007: Alexandra Zhernakova; Behrooz Alizadeh; Marianna R Bevova; Miek A van Leeuwen; Marieke Coenen; Barbara Franke; Lude Franke; Marcel D Posthumus; David A van Heel; Gerrit van der Steege; Timothy Radstake; Pilar Barrera; Bart O Roep; Bobby P C Koeleman; Cisca Wijmenga
Novel association in chromosome 4q27 region with rheumatoid arthritis and confirmation of type 1 diabetes point to a general risk locus for autoimmune diseases.
American journal of human genetics 2007;81(6):1284-8.
2007: Behrooz Alizadeh; Gustavo Valdigem; Marieke Coenen; Alexandra Zhernakova; Barbara Franke; Alienke J Monsuur; P L C M van Riel; Pilar Barrera; Timothy Radstake; Bart O Roep; Cisca Wijmenga; Bobby P C Koeleman
Association analysis of functional variants of the FcgRIIa and FcgRIIIa genes with type 1 diabetes, celiac disease and rheumatoid arthritis.
Human molecular genetics 2007;16(21):2552-9.
2007: Calin Popa; F H J van den Hoogen; Timothy Radstake; Mihai G Netea; Agnes E Eijsbouts; Martin den Heijer; Jos W M van der Meer; P L C M van Riel; Anton F H Stalenhoef; Pilar Barrera
Modulation of lipoprotein plasma concentrations during long-term anti-TNF therapy in patients with active rheumatoid arthritis.
Annals of the rheumatic diseases 2007;66(11):1503-7.
2007: Hanneke K A Knaapen; Pilar Barrera
Therapy for Whipple's disease.
The Journal of antimicrobial chemotherapy 2007;60(3):457-8.
2007: Marieke Coenen; Erik J M Toonen; Hans Scheffer; Timothy Radstake; Pilar Barrera; Barbara Franke
Pharmacogenetics of anti-TNF treatment in patients with rheumatoid arthritis.
Pharmacogenomics 2007;8(7):761-73.
2007: Niels P Riksen; Gerard A Rongen; Paul Smits; P L C M van Riel; Pilar Barrera
Effect of the 34C>T variant in the AMPD1 gene on the clinical response to methotrexate in patients with rheumatoid arthritis: comment on the article by Wessels et al.
Arthritis and rheumatism 2007;56(2):694; author reply 694-5.
2007: Laëtitia Michou; Sandra Lasbleiz; Anne-Christine Rat; Paola Migliorini; Alejandro Balsa; René Westhovens; Pilar Barrera; Helena Alves; Céline Pierlot; Elodie Glikmans; Sophie Garnier; Jean Dausset; Carlos Vaz; Manuela Fernandes; Elisabeth Petit-Teixeira; Isabelle Lemaire; Dora Pascual-Salcedo; Stefano Bombardieri; Jan Dequeker; Timothy Radstake; Piet Van Riel; L B A Van De Putte; Antonio Lopes-Vaz; Bernard Prum; Thomas Bardin; Philippe Dieudé; François Cornélis
Linkage proof for PTPN22, a rheumatoid arthritis susceptibility gene and a human autoimmunity gene.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(5):1649-54.
2006: Timothy Radstake; Barbara Franke; Mark Wenink; K C A M Nabbe; Marieke Coenen; Paco M J Welsing; Ezio Bonvini; Scott Koenig; Wim B van den Berg; Pilar Barrera; P L C M van Riel
The functional variant of the inhibitory Fcgamma receptor IIb (CD32B) is associated with the rate of radiologic joint damage and dendritic cell function in rheumatoid arthritis.
Arthritis and rheumatism 2006;54(12):3828-37.
2006: Niels P Riksen; Pilar Barrera; Petra H H van den Broek; P L C M van Riel; Paul Smits; Gerard A Rongen
Methotrexate modulates the kinetics of adenosine in humans in vivo.
Annals of the rheumatic diseases 2006;65(4):465-70.
2006: Leo A B Joosten; Mihai G Netea; Soo-Hyun Kim; Do-Young Yoon; Birgitte Oppers-Walgreen; Timothy Radstake; Pilar Barrera; Fons A J van de Loo; Charles A Dinarello; Wim B van den Berg
IL-32, a proinflammatory cytokine in rheumatoid arthritis.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(9):3298-303.
2005: Timothy Radstake; K C A M Nabbe; Mark Wenink; Mieke F Roelofs; A Oosterlaar; Antoine W T van Lieshout; Pilar Barrera; P L E M van Lent; Wim B van den Berg
Dendritic cells from patients with rheumatoid arthritis lack the interleukin 13 mediated increase of Fc gamma RII expression, which has clear functional consequences.
Annals of the rheumatic diseases 2005;64(12):1737-43.
2005: Alexandra Zhernakova; Peter Eerligh; Pilar Barrera; Joanna Wesoly; Joanna Z Weseloy; Tom W J Huizinga; Bart O Roep; Cisca Wijmenga; Bobby P C Koeleman
CTLA4 is differentially associated with autoimmune diseases in the Dutch population.
Human genetics 2005;118(1):58-66.
2005: E H J G Aarntzen; P L C M van Riel; Pilar Barrera
Refractory adult onset Still's disease and hypersensitivity to non-steroidal anti-inflammatory drugs and cyclo-oxygenase-2 inhibitors: are biological agents the solution?
Annals of the rheumatic diseases 2005;64(10):1523-4.
2005: Alexandra Zhernakova; Peter Eerligh; Cisca Wijmenga; Pilar Barrera; Bart O Roep; Bobby P C Koeleman
Differential association of the PTPN22 coding variant with autoimmune diseases in a Dutch population.
Genes and immunity 2005;6(6):459-61.
2005: Calin Popa; Mihai G Netea; Timothy Radstake; P L C M van Riel; Pilar Barrera; J W M Van Der Meer
Markers of inflammation are negatively correlated with serum leptin in rheumatoid arthritis.
Annals of the rheumatic diseases 2005;64(8):1195-8.
2005: Calin Popa; Mihai G Netea; Pilar Barrera; Timothy Radstake; P L C M van Riel; Bart Jan Kullberg; Jos W M van der Meer
Cytokine production of stimulated whole blood cultures in rheumatoid arthritis patients receiving short-term infliximab therapy.
Cytokine 2005;30(2):72-7.
2005: Timothy Radstake; Robbert van der Voort; M ten Brummelhuis; Maarten C de Waal Malefijt; Maaike W G Looman; Carl G Figdor; Wim B van den Berg; Pilar Barrera; Gosse J Adema
Increased expression of CCL18, CCL19, and CCL17 by dendritic cells from patients with rheumatoid arthritis, and regulation by Fc gamma receptors.
Annals of the rheumatic diseases 2005;64(3):359-67.
2005: Antoine W T van Lieshout; Pilar Barrera; R L Smeets; Gerard J Pesman; P L C M van Riel; Wim B van den Berg; Timothy Radstake
Inhibition of TNF alpha during maturation of dendritic cells results in the development of semi-mature cells: a potential mechanism for the beneficial effects of TNF alpha blockade in rheumatoid arthritis.
Annals of the rheumatic diseases 2005;64(3):408-14.
2004: Timothy Radstake; Mieke F Roelofs; Yvonne Bastiaansen-Jenniskens; Birgitte Oppers-Walgreen; P L C M van Riel; Pilar Barrera; Leo A B Joosten; Wim B van den Berg
Expression of toll-like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin-12 and interleukin-18 via interferon-gamma.
Arthritis and rheumatism 2004;50(12):3856-65.
2004: Timothy Radstake; Arjen B Blom; Annet W Slöetjes; E O F van Gorselen; Gerard J Pesman; Linda P H Engelen; Ruurd Torensma; Wim B van den Berg; Carl G Figdor; P L E M van Lent; Gosse J Adema; Pilar Barrera
Increased FcgammaRII expression and aberrant tumour necrosis factor alpha production by mature dendritic cells from patients with active rheumatoid arthritis.
Annals of the rheumatic diseases 2004;63(12):1556-63.
2004: Timothy Radstake; P L E M van Lent; Gerard J Pesman; Arjen B Blom; Fred G J Sweep; J Rönnelid; Gosse J Adema; Pilar Barrera; Wim B van den Berg
High production of proinflammatory and Th1 cytokines by dendritic cells from patients with rheumatoid arthritis, and down regulation upon FcgammaR triggering.
Annals of the rheumatic diseases 2004;63(6):696-702.
2004: Erik R Vossenaar; Timothy Radstake; Annemarie van der Heijden; M A M van Mansum; C Dieteren; D-J de Rooij; Pilar Barrera; Albert J W Zendman; Walther J van Venrooij
Expression and activity of citrullinating peptidylarginine deiminase enzymes in monocytes and macrophages.
Annals of the rheumatic diseases 2004;63(4):373-81.
2004: Timothy Radstake; Barbara Franke; Suzanne Hanssen; Mihai G Netea; Paco M J Welsing; Pilar Barrera; Leo A B Joosten; P L C M van Riel; Wim B van den Berg
The Toll-like receptor 4 Asp299Gly functional variant is associated with decreased rheumatoid arthritis disease susceptibility but does not influence disease severity and/or outcome.
Arthritis and rheumatism 2004;50(3):999-1001.
2003: Pilar Barrera; Wim J G Oyen; Otto Boerman; P L C M van Riel
Scintigraphic detection of tumour necrosis factor in patients with rheumatoid arthritis.
Annals of the rheumatic diseases 2003;62(9):825-8.
2003: Milan Tjioe; M J P Gerritsen; Alfons A den Broeder; Candida A E M van Hooijdonk; E J A Kroot; P L C M van Riel; Pilar Barrera; P C M van de Kerkhof
Adalimumab, a fully human anti-TNF-alpha monoclonal antibody, treatment does not influence experimental UV response in the skin of rheumatoid arthritis patients.
Experimental dermatology 2003;12(4):460-5.
2003: Mihai G Netea; Timothy Radstake; Leo A Joosten; Jos W M van der Meer; Pilar Barrera; Bart Jan Kullberg
Salmonella septicemia in rheumatoid arthritis patients receiving anti-tumor necrosis factor therapy: association with decreased interferon-gamma production and Toll-like receptor 4 expression.
Arthritis and rheumatism 2003;48(7):1853-7.
2003: Timothy Radstake; Elisabeth Petit; Cieline Pierlot; L B A Van De Putte; François Cornelis; Pilar Barrera
Role of Fcgamma receptors IIA, IIIA, and IIIB in susceptibility to rheumatoid arthritis.
The Journal of rheumatology 2003;30(5):926-33.
2003: Arjen B Blom; Timothy Radstake; A E M Holthuysen; Annet W Slöetjes; Gerard J Pesman; Fred G J Sweep; Fons A J van de Loo; Leo A B Joosten; Pilar Barrera; P L E M van Lent; Wim B van den Berg
Increased expression of Fcgamma receptors II and III on macrophages of rheumatoid arthritis patients results in higher production of tumor necrosis factor alpha and matrix metalloproteinase.
Arthritis and rheumatism 2003;48(4):1002-14.
2003: P L E M van Lent; Carl G Figdor; Pilar Barrera; Karin van Ginkel; Annet W Slöetjes; Wim B van den Berg; Ruurd Torensma
Expression of the dendritic cell-associated C-type lectin DC-SIGN by inflammatory matrix metalloproteinase-producing macrophages in rheumatoid arthritis synovium and interaction with intercellular adhesion molecule 3-positive T cells.
Arthritis and rheumatism 2003;48(2):360-9.
2003: Leo A B Joosten; Timothy Radstake; Erik Lubberts; Liduine Van Den Bersselaar; P L C M van Riel; P L E M van Lent; Pilar Barrera; Wim B van den Berg
Association of interleukin-18 expression with enhanced levels of both interleukin-1beta and tumor necrosis factor alpha in knee synovial tissue of patients with rheumatoid arthritis.
Arthritis and rheumatism 2003;48(2):339-47.
2003: Alfons A den Broeder; Geert J A Wanten; Wim J G Oyen; Ton H J Naber; P L C M van Riel; Pilar Barrera
Neutrophil migration and production of reactive oxygen species during treatment with a fully human anti-tumor necrosis factor-alpha monoclonal antibody in patients with rheumatoid arthritis.
The Journal of rheumatology 2003;30(2):232-7.
2003: Gerald J D Hengstman; F H J van den Hoogen; Pilar Barrera; M G Netea; Allan J Pieterse; L B A Van De Putte; B G M van Engelen
Successful treatment of dermatomyositis and polymyositis with anti-tumor-necrosis-factor-alpha: preliminary observations.
European neurology 2003;50(1):10-5.
2002: Pilar Barrera; A van der Maas; Annelies van Ede; B A L M Kiemeney; R F J M Laan; L B A Van De Putte; P L C M van Riel
Drug survival, efficacy and toxicity of monotherapy with a fully human anti-tumour necrosis factor-alpha antibody compared with methotrexate in long-standing rheumatoid arthritis.
Rheumatology (Oxford, England) 2002;41(4):430-9.
2002: Alfons A den Broeder; Leo A B Joosten; T Saxne; D Heinegård; Helmut Fenner; André M M Miltenburg; W L H Frasa; Lambertus J H Van Tits; W A Buurman; P L C M van Riel; L B A Van De Putte; Pilar Barrera
Long term anti-tumour necrosis factor alpha monotherapy in rheumatoid arthritis: effect on radiological course and prognostic value of markers of cartilage turnover and endothelial activation.
Annals of the rheumatic diseases 2002;61(4):311-8.
2001: Pilar Barrera; S Fauré; JF Prud'homme; Alejandro Balsa; Paola Migliorini; Daniele Chimenti; Timothy Radstake; L B A Van De Putte; Dora Pascual-Salcedo; René Westhovens; K Maenaut; Helena Alves; Antonio Lopes-Vaz; C Stravopoulos; Marilyn Spyropoulou; P Fritz; Thomas Bardin; Dominique Charron; Virginia Lepage; Maria Martinez; François Cornélis
European genetic study on rheumatoid arthritis: is there a linkage of the interleukin-1 (IL-1), IL-10 or IL-4 genes to RA?
Clinical and experimental rheumatology 2001;19(6):709-14.
2001: Pilar Barrera; Leo A B Joosten; Alfons A den Broeder; L B A Van De Putte; P L C M van Riel; Wim B van den Berg
Effects of treatment with a fully human anti-tumour necrosis factor alpha monoclonal antibody on the local and systemic homeostasis of interleukin 1 and TNFalpha in patients with rheumatoid arthritis.
Annals of the rheumatic diseases 2001;60(7):660-9.
2001: Alejandro Balsa; Pilar Barrera; René Westhovens; Helena Alves; K Maenaut; Dora Pascual-Salcedo; François Cornélis; Thomas Bardin; Lucrezia Riente; Timothy Radstake; G de Almeida; Virginia Lepage; C Stravopoulos; M Spaepen; Antonio Lopes-Vaz; D Charron; M Martinez; J F Prudhomme; Paola Migliorini; P Fritz
Clinical and immunogenetic characteristics of European multicase rheumatoid arthritis families.
Annals of the rheumatic diseases 2001;60(6):573-6.
2001: Pilar Barrera; Alejandro Balsa; Helena Alves; René Westhovens; K Maenaut; François Cornélis; P Fritz; Thomas Bardin; M Ceu Maia; Antonio Lopes-Vaz; Dora Pascual-Salcedo; Emilio G De-la-Concha; Timothy Radstake; L B A Van De Putte; Paola Migliorini; J F Prudhomme; Dominique Charron; Marilyn Spyropoulou; A Mendes; M Spaepen; Maria Martinez; C Stavropoulos
Noninherited maternal antigens do not increase the susceptibility for familial rheumatoid arthritis. European Consortium on Rheumatoid Arthritis Families (ECRAF).
The Journal of rheumatology 2001;28(5):968-74.
2001: Timothy Radstake; Pilar Barrera; M J Albers; Hilde L Swinkels; L B A Van De Putte; P L C M van Riel
Genetic anticipation in rheumatoid arthritis in Europe. European Consortium on Rheumatoid Arthritis Families.
The Journal of rheumatology 2001;28(5):962-7.
2000: Pilar Barrera; A Blom; P L E M van Lent; L van Bloois; J H Beijnen; N van Rooijen; Maarten C de Waal Malefijt; L B A Van De Putte; G Storm; Wim B van den Berg
Synovial macrophage depletion with clodronate-containing liposomes in rheumatoid arthritis.
Arthritis and rheumatism 2000;43(9):1951-9.
2000: Pilar Barrera; CJ van der Laken; Otto Boerman; Wim J G Oyen; MT van de Ven; P L E M van Lent; L B van de Putte; Frans H M Corstens
Radiolabelled interleukin-1 receptor antagonist for detection of synovitis in patients with rheumatoid arthritis.
Rheumatology (Oxford, England) 2000;39(8):870-4.
2000: Pilar Barrera; Alejandro Balsa; Helena Alves; René Westhovens; K Maenaut; François Cornélis; P Fritz; Thomas Bardin; G de Almeida; Antonio Lopes-Vaz; Dora Pascual-Salcedo; Emilio G De-la-Concha; Timothy Radstake; L B A Van De Putte; Paola Migliorini; JF Prud'homme; Dominique Charron; Marilyn Spyropoulou; A Mendes; M Spaepen; Maria Martinez; Virginia Lepage; C Stravopoulos
Noninherited maternal antigens do not play a role in rheumatoid arthritis susceptibility in Europe. European Consortium on Rheumatoid Arthritis Families.
Arthritis and rheumatism 2000;43(4):758-64.
2000: Timothy Radstake; Pilar Barrera; JM Albers; Hilde L Swinkels; L B A Van De Putte; P L C M van Riel
Familial vs sporadic rheumatoid arthritis (RA). A prospective study in an early RA inception cohort.
Rheumatology (Oxford, England) 2000;39(3):267-73.
1999: RJ Rodenburg; F H J van den Hoogen; Pilar Barrera; Walther J van Venrooij; L B A Van De Putte
Superinduction of interleukin 8 mRNA in activated monocyte derived macrophages from rheumatoid arthritis patients.
Annals of the rheumatic diseases 1999;58(10):648-52.
1999: P A te Boekhorst; Pilar Barrera; R F J M Laan; L B A Van De Putte
Hepatotoxicity of parenteral gold therapy in rheumatoid arthritis: a case report and review of the literature.
Clinical and experimental rheumatology 1999;17(3):359-62.
1999: Pilar Barrera; Timothy Radstake; JM Albers; P L C M van Riel; L B A Van De Putte
Familial aggregation of rheumatoid arthritis in The Netherlands: a cross-sectional hospital-based survey. European Consortium on Rheumatoid Arthritis families (ECRAF).
Rheumatology (Oxford, England) 1999;38(5):415-22.
1998: Irene E van der Horst-Bruinsma; J M W Hazes; G M Th Schreuder; Timothy Radstake; Pilar Barrera; L B van de Putte; D Mustamu; Dirkjan van Schaardenburg; Ferdinand C Breedveld; René R P De Vries
Influence of non-inherited maternal HLA-DR antigens on susceptibility to rheumatoid arthritis.
Annals of the rheumatic diseases 1998;57(11):672-5.
1998: Tim Jansen; Pilar Barrera; B G van Engelen; N Cox; R F J M Laan; L B A Van De Putte
Dermatomyositis with subclinical myositis and spontaneous pneumomediastinum with pneumothorax: case report and review of the literature.
Clinical and experimental rheumatology 1998;16(6):733-5.
1998: Tim Jansen; H A van Heereveld; R F J M Laan; Pilar Barrera; L B A Van De Putte
Septic arthritis with Listeria monocytogenes during low-dose methotrexate.
Journal of internal medicine 1998;244(1):87-90.
1998: Pilar Barrera; Alfons A den Broeder; F H J van den Hoogen; B G van Engelen; L B A Van De Putte
Postural changes, dysphagia, and systemic sclerosis.
Annals of the rheumatic diseases 1998;57(6):331-8.
1996: Pilar Barrera; AM Boerbooms; L B A Van De Putte; J W van der Meer
Effects of antirheumatic agents on cytokines.
Seminars in arthritis and rheumatism 1996;25(4):234-53.
1995: Pilar Barrera; Cees Haagsma; AM Boerbooms; P L C M van Riel; G F Borm; L B A Van De Putte; J W Van der Meer
Effect of methotrexate alone or in combination with sulphasalazine on the production and circulating concentrations of cytokines and their antagonists. Longitudinal evaluation in patients with rheumatoid arthritis.
British journal of rheumatology 1995;34(8):747-55.
1994: Pilar Barrera; AM Boerbooms; Pierre N M Demacker; L B A Van De Putte; H Gallati; J W van der Meer
Circulating concentrations and production of cytokines and soluble receptors in rheumatoid arthritis patients: effects of a single dose methotrexate.
British journal of rheumatology 1994;33(11):1017-24.
1994: Pilar Barrera; A Van Ede; R F J M Laan; P L C M van Riel; AM Boerbooms; L B A Van De Putte
Methotrexate-related pulmonary complications in patients with rheumatoid arthritis: cluster of five cases in a period of three months.
Annals of the rheumatic diseases 1994;53(7):479-80.
1994: Pilar Barrera; R F J M Laan; P L C M van Riel; P N Dekhuijzen; AM Boerbooms; L B A Van De Putte
Methotrexate-related pulmonary complications in rheumatoid arthritis.
Annals of the rheumatic diseases 1994;53(7):434-9.
1994: Pilar Barrera; AM Boerbooms; R W Sauerwein; Pierre N M Demacker; L B A Van De Putte; J W van der Meer
Interference of circulating azathioprine but not methotrexate or sulfasalazine with measurements of interleukin-6 bioactivity.
Lymphokine and cytokine research 1994;13(2):155-9.
1993: Pilar Barrera; AM Boerbooms; E M Janssen; R W Sauerwein; H Gallati; J Mulder; T de Boo; Pierre N M Demacker; L B A Van De Putte; J W van der Meer
Circulating soluble tumor necrosis factor receptors, interleukin-2 receptors, tumor necrosis factor alpha, and interleukin-6 levels in rheumatoid arthritis. Longitudinal evaluation during methotrexate and azathioprine therapy.
Arthritis and rheumatism 1993;36(8):1070-9.
1993: L B A Van De Putte; AM Boerbooms; Pilar Barrera; P J Kerstens; M E Jeurissen
Methotrexate: anti-inflammatory or immunosuppressive?
Clinical and experimental rheumatology 1993;11 Suppl 8():S97-9.
1992: Pilar Barrera; P L C M van Riel; A J de Jong; AM Boerbooms; L B Van de Putte
Recurrent and migratory reflex sympathetic dystrophy syndrome.
Clinical rheumatology 1992;11(3):416-21.
1992: Pilar Barrera; E M Janssen; Pierre N M Demacker; Jack F M Wetzels; J W van der Meer
Removal of interleukin-1 beta and tumor necrosis factor from human plasma by in vitro dialysis with polyacrylonitrile membranes.
Lymphokine and cytokine research 1992;11(2):99-104.