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Jordi Barretina

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Rodrigo Dienstmann; Jordi Rodon; Jordi Barretina; Josep Tabernero
Genomic medicine frontier in human solid tumors: prospects and challenges.
Anja Lachenmayer; Clara Alsinet-Armengol; Jordi Barretina; Jordi Bruix; Laia Cabellos; Scott L Friedman; Yujin Hoshida; Vincenzo Mazzaferro; Beatriz Minguez; Philippa Newell; Radoslav Savic; Myron Schwartz; Swan Thung; Sara Toffanin; Hung-Wen Tsai; Augusto Villanueva; Stephen C Ward; Josep M Llovet
Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib.
Austin M Dulak; Peter C Enzinger; Cameron Fox; Tony E Godfrey; Yu Imamura; Lin Lin; James D Luketich; Matthew Meyerson; Shuji Ogino; Arjun Pennathur; Alex H Ramos; franco roviello; Gordon Saksena; Steven E Schumacher; Byoungyong Shim; Ramesh A Shivdasani; Josep Tabernero; Jasper van Lieshout; Sylvan C Baca; Santhoshi Bandla; Jordi Barretina; Jose Baselga; David G Beer; Rameen Beroukhim; Giovanni Corso; Adam J Bass
Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis.

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All Publications

2013: Rodrigo Dienstmann; Jordi Rodon; Jordi Barretina; Josep Tabernero
Genomic medicine frontier in human solid tumors: prospects and challenges.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2013;31(15):1874-84.
2012: Anja Lachenmayer; Clara Alsinet-Armengol; Jordi Barretina; Jordi Bruix; Laia Cabellos; Scott L Friedman; Yujin Hoshida; Vincenzo Mazzaferro; Beatriz Minguez; Philippa Newell; Radoslav Savic; Myron Schwartz; Swan Thung; Sara Toffanin; Hung-Wen Tsai; Augusto Villanueva; Stephen C Ward; Josep M Llovet
Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(18):4997-5007.
2012: Austin M Dulak; Peter C Enzinger; Cameron Fox; Tony E Godfrey; Yu Imamura; Lin Lin; James D Luketich; Matthew Meyerson; Shuji Ogino; Arjun Pennathur; Alex H Ramos; franco roviello; Gordon Saksena; Steven E Schumacher; Byoungyong Shim; Ramesh A Shivdasani; Josep Tabernero; Jasper van Lieshout; Sylvan C Baca; Santhoshi Bandla; Jordi Barretina; Jose Baselga; David G Beer; Rameen Beroukhim; Giovanni Corso; Adam J Bass
Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis.
Cancer research 2012;72(17):4383-93.
2012: Y Shrestha; S R Thomas; S Wang; Barbara A Weir; J J Zhao; Jordi Barretina; Rameen Beroukhim; J S Boehm; J Du; T R Golub; F He; K Polyak; E J Schafer; William C Hahn
PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling.
Oncogene 2012;31(29):3397-408.
2011: Richard Possemato; David E Root; Shalini Sethumadhavan; Yoav D Shaul; Nicolas Stransky; Zhi-Yang Tsun; Hin-Koon Woo; Bingbing Yuan; Jordi Barretina; Francesca G Barrett; kivanc birsoy; Elena F Brachtel; Albert M Chan; Walter W Chen; Glenn S Cowley; Edward M Driggers; Levi A Garraway; Peggy P Hsu; Hyun G Jang; Abhishek K Jha; Nada Y Kalaany; Dohoon Kim; Kevin M Marks; Mari Mino-Kenudson; Kathleen Ottina; Michael E Pacold; David M Sabatini
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
Nature 2011;476(7360):346-50.
2011: Barry S Taylor; Cristina R Antonescu; Jordi Barretina; ROBERT G MAKI; Samuel Singer; Marc Ladanyi
Advances in sarcoma genomics and new therapeutic targets.
Nature reviews. Cancer 2011;11(8):541-57.
2011: Hiu Wing Cheung; Glenn S Cowley; Ronny Drapkin; Alexandra East; Levi A Garraway; Gad Getz; Shuba Gopal; Joshua Gould; Levi D Ali; Jordi Barretina; Sangeeta N Bhatia; Jesse S Boehm; Jessica Hsiao; Guozhi Jiang; Eric S Lander; Patrick H Lizotte; Biao Luo; Craig H Mermel; Jill P Mesirov; Matthew Meyerson; Yin Ren; David E Root; Scott Rusin; Justine A Scott; Nicolas Stransky; Pablo Tamayo; Aviad Tsherniak; Barbara A Weir; Terence C Wong; William C Hahn
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(30):12372-7.
2011: Alison L Dooley; Levi A Garraway; Shantanu Banerji; Jordi Barretina; Roderick T Bronson; Derek Y Chiang; Denise Crowley; Talya L Dayton; Matthew Meyerson; Stephanie Senna; Eric L Snyder; Nicolas Stransky; Charles A Whittaker; Monte M Winslow; Tyler Jacks
Nuclear factor I/B is an oncogene in small cell lung cancer.
Genes & development 2011;25(14):1470-5.
2010: Katherine Anne Janeway; Mei-Jun Zhu; Jordi Barretina; Antonio Perez-Atayde; George D Demetri; Jonathan A Fletcher
Strong expression of IGF1R in pediatric gastrointestinal stromal tumors without IGF1R genomic amplification.
International journal of cancer. Journal international du cancer 2010;127(11):2718-22.
2010: Michael Berger; Joshua Z Levin; Krishna Vijayendran; Andrey Sivachenko; Xian Adiconis; Jared Maguire; Laura A Johnson; James Robinson; Roel G Verhaak; Carrie Sougnez; Robert C Onofrio; Liuda Ziaugra; Kristian Cibulskis; Elisabeth Laine; Jordi Barretina; Wendy Winckler; David E Fisher; Gad Getz; Matthew Meyerson; David B Jaffe; Stacey B Gabriel; Eric S Lander; Reinhard Dummer; Andreas Gnirke; Chad Nusbaum; Levi A Garraway
Integrative analysis of the melanoma transcriptome.
Genome research 2010;20(4):413-27.
2009: Alex H Ramos; Amit Dutt; Craig Mermel; Sven Perner; Jeonghee Cho; Christopher J Lafargue; Laura A Johnson; Ann-Cathrin Stiedl; Kumiko E Tanaka; Adam J Bass; Jordi Barretina; Barbara A Weir; Rameen Beroukhim; Roman K Thomas; John D Minna; Lucian R Chirieac; Neal Lindeman; Thomas J Giordano; David G Beer; Patrick Wagner; Ignacio I Wistuba; Mark A Rubin; Matthew Meyerson
Amplification of chromosomal segment 4q12 in non-small cell lung cancer.
Cancer biology & therapy 2009;8(21):2042-50.
2009: Christina Gewinner; Zhigang C Wang; Andrea Richardson; Julie T Feldstein; Dariush Etemadmoghadam; David D L Bowtell; Jordi Barretina; William M Lin; Lucia Rameh; Leonardo Salmena; Pier Paolo Pandolfi; Lewis C Cantley
Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling.
Cancer cell 2009;16(2):115-25.
2009: Mark M Pomerantz; Nasim Ahmadiyeh; Li Jia; Paula Herman; Michael P Verzi; Harshavardhan Doddapaneni; Christine A Beckwith; Jennifer A Chan; Adam Hills; Matt Davis; Keluo Yao; Sarah M Kehoe; Heinz-Josef Lenz; Christopher A Haiman; Chunli Yan; Brian E Henderson; Baruch Frenkel; Jordi Barretina; Adam Bass; Josep Tabernero; José Baselga; Meredith M Regan; J Robert Manak; Ramesh A Shivdasani; Gerhard A Coetzee; Matthew L Freedman
The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer.
Nature genetics 2009;41(8):882-4.
2008: Peter Mulligan; Thomas F Westbrook; Matthias Ottinger; Natalya Pavlova; Bin Chang; Eric Macia; Yu-Jiang Shi; Jordi Barretina; Jinsong Liu; Peter M Howley; Stephen J Elledge; Yang Shi
CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation.
Molecular cell 2008;32(5):718-26.
2008: Ron Firestein; Adam J Bass; So Young Kim; Ian F Dunn; Serena J Silver; Isil Guney; Ellen Freed; Azra H Ligon; Natalie Vena; Shuji Ogino; Milan G Chheda; Pablo Tamayo; Stephen Finn; Yashaswi Shrestha; Jesse S Boehm; Supriya Jain; Emeric Bojarski; Craig Mermel; Jordi Barretina; Jennifer A Chan; Jose Baselga; Josep Tabernero; David E Root; Charles S Fuchs; Massimo Loda; Ramesh A Shivdasani; Matthew Meyerson; William C Hahn
CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity.
Nature 2008;455(7212):547-51.
2008: Barry S Taylor; Jordi Barretina; Nicholas D Socci; Penelope DeCarolis; Marc Ladanyi; Matthew Meyerson; Samuel Singer; Chris Sander
Functional copy-number alterations in cancer.
PloS one 2008;3(9):e3179.
2004: Julià Blanco; Berta Bosch; Maria Teresa Fernández-Figueras; Jordi Barretina; Bonaventura Clotet; José A Esté
High level of coreceptor-independent HIV transfer induced by contacts between primary CD4 T cells.
The Journal of biological chemistry 2004;279(49):51305-14.
2004: Julià Blanco; Jordi Barretina; Bonaventura Clotet; José A Esté
R5 HIV gp120-mediated cellular contacts induce the death of single CCR5-expressing CD4 T cells by a gp41-dependent mechanism.
Journal of leukocyte biology 2004;76(4):804-11.
2004: Jordi Barretina; Julià Blanco; Anna Bonjoch; Anuska Llano; Bonaventura Clotet; José A Esté
Immunological and virological study of enfuvirtide-treated HIV-positive patients.
AIDS (London, England) 2004;18(12):1673-82.
2003: Jordi Barretina; J Juncà; Anuska Llano; Arantxa Gutiérrez; A Flores; Julià Blanco; Bonaventura Clotet; José A Esté
CXCR4 and SDF-1 expression in B-cell chronic lymphocytic leukemia and stage of the disease.
Annals of hematology 2003;82(8):500-5.
2003: Jordi Barretina; Julià Blanco; Mercedes Armand-Ugón; Arantxa Gutiérrez; Bonaventura Clotet; José A Esté
Anti-HIV-1 activity of enfuvirtide (T-20) by inhibition of bystander cell death.
Antiviral therapy 2003;8(2):155-61.
2003: Anuska Llano; Jordi Barretina; Arantxa Gutiérrez; Bonaventura Clotet; José A Esté
Interleukin-7-dependent production of RANTES that correlates with human immunodeficiency virus disease progression.
Journal of virology 2003;77(7):4389-95.
2003: Mercedes Armand-Ugón; Miguel E Quiñones-Mateu; Arantxa Gutiérez; Jordi Barretina; Julià Blanco; Dominique Schols; Erik De Clercq; Bonaventura Clotet; José A Esté
Reduced fitness of HIV-1 resistant to CXCR4 antagonists.
Antiviral therapy 2003;8(1):1-8.
2003: Julià Blanco; Jordi Barretina; Karine F Ferri; Etienne Jacotot; Arantxa Gutiérrez; Mercedes Armand-Ugón; Cecilia Cabrera; Guido Kroemer; Bonaventura Clotet; José A Esté
Cell-surface-expressed HIV-1 envelope induces the death of CD4 T cells during GP41-mediated hemifusion-like events.
Virology 2003;305(2):318-29.
2002: Maria Castedo; Thomas Roumier; Julià Blanco; Karine F Ferri; Jordi Barretina; lionel tintignac; Karine Andreau; Jean-Luc PERFETTINI; Alessandra Amendola; Roberta Nardacci; Philip Leduc; Donald Ingber; Sabine Druillennec; Bernard P Roques; Serge Leibovitch; Montserrat Vilella-Bach; Jie Chen; José A Este; Nazanine Modjtahedi; Mauro Piacentini; Guido Kroemer
Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope.
The EMBO journal 2002;21(15):4070-80.
2002: Julià Blanco; Jordi Barretina; Arantxa Gutiérrez; Mercedes Armand-Ugón; Cecilia Cabrera; Bonaventura Clotet; José A Esté
Preferential attachment of HIV particles to activated and CD45RO+CD4+ T cells.
AIDS research and human retroviruses 2002;18(1):27-38.
2002: Cecilia Cabrera; Arantxa Gutiérrez; Jordi Barretina; Julià Blanco; Alexander Litovchick; Aviva Lapidot; Bonaventura Clotet; José A Esté
Anti-HIV activity of a novel aminoglycoside-arginine conjugate.
Antiviral research 2002;53(1):1-8.
2001: Anuska Llano; Jordi Barretina; Arantxa Gutiérrez; Julià Blanco; Cecilia Cabrera; Bonaventura Clotet; José A Esté
Interleukin-7 in plasma correlates with CD4 T-cell depletion and may be associated with emergence of syncytium-inducing variants in human immunodeficiency virus type 1-positive individuals.
Journal of virology 2001;75(21):10319-25.
2001: Maria Castedo; Karine F Ferri; Julià Blanco; Thomas Roumier; Nathanael Larochette; Jordi Barretina; Alessandra Amendola; Roberta Nardacci; Didier Métivier; J A Este; Mauro Piacentini; Guido Kroemer
Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation.
The Journal of experimental medicine 2001;194(8):1097-110.
2001: Anuska Llano; Jordi Barretina; Julià Blanco; Arantxa Gutiérrez; Bonaventura Clotet; José A Esté
Stromal-cell-derived factor 1 prevents the emergence of the syncytium-inducing phenotype of HIV-1 in vivo.
AIDS (London, England) 2001;15(14):1890-2.
2001: Julià Blanco; Jordi Barretina; Cecilia Cabrera; Arantxa Gutiérrez; Bonaventura Clotet; José A Esté
CD4(+) and CD8(+) T cell death during human immunodeficiency virus infection in vitro.
Virology 2001;285(2):356-65.
2000: Cecilia Cabrera; Arantxa Gutiérrez; Julià Blanco; Jordi Barretina; Alexander Litovchick; Aviva Lapidot; AG Evdokimov; Bonaventura Clotet; José A Esté
Anti-human immunodeficiency virus activity of novel aminoglycoside-arginine conjugates at early stages of infection.
AIDS research and human retroviruses 2000;16(7):627-34.
2000: Jordi Barretina; J Blanco; A Gutiérrez; L Puig; Carme Altisent; Teresa Espanol; Isabel Caragol; B Clotet; José A Esté
Evaluation of the putative role of C-C chemokines as protective factors of HIV-1 infection in seronegative hemophiliacs exposed to contaminated hemoderivatives.
Transfusion 2000;40(4):461-7.
2000: Julià Blanco; Jordi Barretina; Geoffrey Henson; Gary J Bridger; Erik De Clercq; Bonaventura Clotet; José A Esté
The CXCR4 antagonist AMD3100 efficiently inhibits cell-surface-expressed human immunodeficiency virus type 1 envelope-induced apoptosis.
Antimicrobial agents and chemotherapy 2000;44(1):51-6.