FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Brian Lord

Research Profile

Chemicals & Drugs

Living Beings

Procedures

Phenomena

Protein Binding

Occupations

Chemistry, Pharmaceutical

Co-author Network

Publications

TOP 3
Pascal Bonaventure; Nicholas I Carruthers; Wenying Chai; Peter De Boer; Jianing Di; Wilhelmus Drinkenburg; Christine Dugovic; Curt A Dvorak; Lisa Dvorak; Ian Fraser; Michelle Kramer; Brian Lord; Diane Nepomuceno; Steve Sands; Jonathan Shelton; Jaskaran Singh; Sue Wilson; Abdellah Ahnaou; Leah Aluisio; Kirk Bertelsen; Timothy W Lovenberg
Translational evaluation of JNJ-18038683, a 5-hydroxytryptamine type 7 receptor antagonist, on rapid eye movement sleep and in major depressive disorder.
Ruggero Galici; Amir H Rezvani; Leah Aluisio; Brian Lord; Edward D Levin; Ian Fraser; Jamin Boggs; Natalie Welty; James R Shoblock; S Timothy Motley; Michael A Letavic; Nicholas I Carruthers; Christine Dugovic; Timothy W Lovenberg; Pascal Bonaventure
JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats.
Pascal Bonaventure; Ian C Fraser; Leah Aluisio; Jamin D Boggs; Brian Lord; Timothy W Lovenberg; James R Shoblock; Ruggero Galici
Pharmacological blockade of serotonin 5-HT₇ receptor reverses working memory deficits in rats by normalizing cortical glutamate neurotransmission.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Brian Lord (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Pascal Bonaventure; Nicholas I Carruthers; Wenying Chai; Peter De Boer; Jianing Di; Wilhelmus Drinkenburg; Christine Dugovic; Curt A Dvorak; Lisa Dvorak; Ian Fraser; Michelle Kramer; Brian Lord; Diane Nepomuceno; Steve Sands; Jonathan Shelton; Jaskaran Singh; Sue Wilson; Abdellah Ahnaou; Leah Aluisio; Kirk Bertelsen; Timothy W Lovenberg
Translational evaluation of JNJ-18038683, a 5-hydroxytryptamine type 7 receptor antagonist, on rapid eye movement sleep and in major depressive disorder.
The Journal of pharmacology and experimental therapeutics 2012;342(2):429-40.
2011: Ruggero Galici; Amir H Rezvani; Leah Aluisio; Brian Lord; Edward D Levin; Ian Fraser; Jamin Boggs; Natalie Welty; James R Shoblock; S Timothy Motley; Michael A Letavic; Nicholas I Carruthers; Christine Dugovic; Timothy W Lovenberg; Pascal Bonaventure
JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats.
Psychopharmacology 2011;214(4):829-41.
2011: Pascal Bonaventure; Ian C Fraser; Leah Aluisio; Jamin D Boggs; Brian Lord; Timothy W Lovenberg; James R Shoblock; Ruggero Galici
Pharmacological blockade of serotonin 5-HT₇ receptor reverses working memory deficits in rats by normalizing cortical glutamate neurotransmission.
PloS one 2011;6(6):e20210.
2010: Alejandro Santillan; Kelly J McClure; Brett D Allison; Brian Lord; Jamin D Boggs; Kirsten L Morton; Anita M Everson; Diane Nepomuceno; Michael A Letavic; Alice Lee-Dutra; Timothy W Lovenberg; Nicholas I Carruthers; Cheryl A Grice
Indole- and benzothiophene-based histamine H3 antagonists.
Bioorganic & medicinal chemistry letters 2010;20(21):6226-30.
2010: Michael A Letavic; Leah Aluisio; John R Atack; Pascal Bonaventure; Nicholas I Carruthers; Christine Dugovic; Anita Everson; Mark A Feinstein; Ian C Fraser; Kenway Hoey; Xiaohui Jiang; John M Keith; Tatiana Koudriakova; Perry Leung; Brian Lord; Timothy W Lovenberg; Kiev S Ly; Kirsten L Morton; S Timothy Motley; Diane Nepomuceno; Michele Rizzolio; Raymond Rynberg; Kia Sepassi; Jonathan Shelton
Pre-clinical characterization of aryloxypyridine amides as histamine H3 receptor antagonists: identification of candidates for clinical development.
Bioorganic & medicinal chemistry letters 2010;20(14):4210-4.
2010: Emily M Stocking; Leah Aluisio; John R Atack; Pascal Bonaventure; Nicholas I Carruthers; Christine Dugovic; Anita Everson; Ian Fraser; Xiaohui Jiang; Perry Leung; Brian Lord; Kiev S Ly; Kirsten L Morton; Diane Nepomuceno; Chandravadan R Shah; Jonathan Shelton; Akinola Soyode-Johnson; Michael A Letavic
Novel substituted pyrrolidines are high affinity histamine H3 receptor antagonists.
Bioorganic & medicinal chemistry letters 2010;20(9):2755-60.
2010: James R Shoblock; Natalie Welty; Diane Nepomuceno; Brian Lord; Leah Aluisio; Ian Fraser; S Timothy Motley; Steve W Sutton; Kirsten Morton; Ruggero Galici; John R Atack; Lisa Dvorak; Devin M Swanson; Nicholas I Carruthers; Curt Dvorak; Timothy W Lovenberg; Pascal Bonaventure
In vitro and in vivo characterization of JNJ-31020028 (N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide), a selective brain penetrant small molecule antagonist of the neuropeptide Y Y(2) receptor.
Psychopharmacology 2010;208(2):265-77.
2009: Devin M Swanson; Chandra R Shah; Brian Lord; Kirsten Morton; Lisa K Dvorak; Curt Mazur; Richard Apodaca; Wei Xiao; Jamin D Boggs; Mark Feinstein; Sandy J Wilson; Ann J Barbier; Pascal Bonaventure; Timothy W Lovenberg; Nicholas I Carruthers
Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists.
European journal of medicinal chemistry 2009;44(11):4413-25.
2009: Curt A Dvorak; Richard Apodaca; Wei Xiao; JIll Jablonowski; Pascal Bonaventure; Christine Dugovic; Jonathan Shelton; Brian Lord; Kirsten Miller; Lisa K Dvorak; Timothy W Lovenberg; Nicholas I Carruthers
Diamine-based human histamine H3 receptor antagonists: (4-aminobutyn-1-yl)benzylamines.
European journal of medicinal chemistry 2009;44(10):4098-106.
2009: Christine Dugovic; Jonathan E Shelton; Leah E Aluisio; Ian C Fraser; Xiaohui Jiang; Steven W Sutton; Pascal Bonaventure; su jin yun; Xiaorong Li; Brian Lord; Curt A Dvorak; Nicholas I Carruthers; Timothy W Lovenberg
Blockade of orexin-1 receptors attenuates orexin-2 receptor antagonism-induced sleep promotion in the rat.
The Journal of pharmacology and experimental therapeutics 2009;330(1):142-51.
2009: Ruggero Galici; Jamin D Boggs; Leah Aluisio; Ian C Fraser; Pascal Bonaventure; Brian Lord; Timothy W Lovenberg
JNJ-10181457, a selective non-imidazole histamine H(3) receptor antagonist, normalizes acetylcholine neurotransmission and has efficacy in translational rat models of cognition.
Neuropharmacology 2009;56(8):1131-7.
2009: Ying Qu; Leah Aluisio; Brian Lord; Jamin Boggs; Kenway Hoey; Curt Mazur; Timothy Lovenberg
Pharmacokinetics and pharmacodynamics of norfluoxetine in rats: Increasing extracellular serotonin level in the frontal cortex.
Pharmacology, biochemistry, and behavior 2009;92(3):469-73.
2009: JIll Jablonowski; Kiev S Ly; Michael Bogenstaetter; Curt A Dvorak; Jamin D Boggs; Lisa K Dvorak; Brian Lord; Kirsten L Miller; Curt Mazur; Sandy J Wilson; Timothy W Lovenberg; Nicholas I Carruthers
Novel imidazole-based histamine H3 antagonists.
Bioorganic & medicinal chemistry letters 2009;19(3):903-7.
2008: Michael A Letavic; John M Keith; Kiev S Ly; Pascal Bonaventure; Mark A Feinstein; Brian Lord; Kirsten L Miller; S Timothy Motley; Diane Nepomuceno; Steven W Sutton; Nicholas I Carruthers
2-Aryloxymethylmorpholine histamine H(3) antagonists.
Bioorganic & medicinal chemistry letters 2008;18(21):5796-9.
2008: Leah Aluisio; Brian Lord; Ann J Barbier; Ian C Fraser; Sandy J Wilson; Jamin D Boggs; Lisa K Dvorak; Michael A Letavic; Bruce E Maryanoff; Nicholas I Carruthers; Pascal Bonaventure; Timothy W Lovenberg
In-vitro and in-vivo characterization of JNJ-7925476, a novel triple monoamine uptake inhibitor.
European journal of pharmacology 2008;587(1-3):141-6.
2008: Kiev S Ly; Michael A Letavic; John M Keith; Jennifer M Miller; Emily M Stocking; Ann J Barbier; Pascal Bonaventure; Brian Lord; Xiaohui Jiang; Jamin D Boggs; Lisa Dvorak; Kirsten L Miller; Diane Nepomuceno; Sandy J Wilson; Nicholas I Carruthers
Synthesis and biological activity of piperazine and diazepane amides that are histamine H3 antagonists and serotonin reuptake inhibitors.
Bioorganic & medicinal chemistry letters 2008;18(1):39-43.
2007: Ann J Barbier; Leah Aluisio; Brian Lord; Ying Qu; Sandy J Wilson; Jamin D Boggs; Pascal Bonaventure; Kirsten Miller; Ian Fraser; Lisa Dvorak; Cindy Pudiak; Christine Dugovic; Jonathan Shelton; Curt Mazur; Michael A Letavic; Nicholas I Carruthers; Timothy W Lovenberg
Pharmacological characterization of JNJ-28583867, a histamine H(3) receptor antagonist and serotonin reuptake inhibitor.
European journal of pharmacology 2007;576(1-3):43-54.
2007: Michael A Letavic; Emily M Stocking; Ann J Barbier; Pascal Bonaventure; Jamin D Boggs; Brian Lord; Kirsten L Miller; Sandy J Wilson; Nicholas I Carruthers
Benzylamine histamine H(3) antagonists and serotonin reuptake inhibitors.
Bioorganic & medicinal chemistry letters 2007;17(17):4799-803.
2007: John M Keith; Leslie A Gomez; Ann J Barbier; Sandy J Wilson; Jamin D Boggs; Brian Lord; Curt Mazur; Leah Aluisio; Timothy W Lovenberg; Nicholas I Carruthers
Pyrrolidino-tetrahydroisoquinolines bearing pendant heterocycles as potent dual H3 antagonist and serotonin transporter inhibitors.
Bioorganic & medicinal chemistry letters 2007;17(15):4374-7.
2007: John M Keith; Leslie A Gomez; Ronald L Wolin; Ann J Barbier; Sandy J Wilson; Jamin D Boggs; Curt Mazur; Ian C Fraser; Brian Lord; Leah Aluisio; Timothy W Lovenberg; Nicholas I Carruthers
Pyrrolidino-tetrahydroisoquinolines as potent dual H3 antagonist and serotonin transporter inhibitors.
Bioorganic & medicinal chemistry letters 2007;17(9):2603-7.
2007: Pascal Bonaventure; Lisa Kelly; Leah Aluisio; Jonathan Shelton; Brian Lord; Ruggero Galici; Kirsten Miller; John Atack; Timothy W Lovenberg; Christine Dugovic
Selective blockade of 5-hydroxytryptamine (5-HT)7 receptors enhances 5-HT transmission, antidepressant-like behavior, and rapid eye movement sleep suppression induced by citalopram in rodents.
The Journal of pharmacology and experimental therapeutics 2007;321(2):690-8.
2007: Michael A Letavic; John M Keith; Kiev S Ly; Ann J Barbier; Jamin D Boggs; Sandy J Wilson; Brian Lord; Timothy W Lovenberg; Nicholas I Carruthers
Novel naphthyridines are histamine H3 antagonists and serotonin reuptake transporter inhibitors.
Bioorganic & medicinal chemistry letters 2007;17(9):2566-9.
2007: Pascal Bonaventure; Michael A Letavic; Christine Dugovic; S Wilson; Leah Aluisio; Cindy Pudiak; Brian Lord; Curt Mazur; Fredrik Kamme; S Nishino; Nicholas I Carruthers; Timothy W Lovenberg
Histamine H3 receptor antagonists: from target identification to drug leads.
Biochemical pharmacology 2007;73(8):1084-96.
2007: Michael A Letavic; John M Keith; JIll Jablonowski; Emily M Stocking; Leslie A Gomez; Kiev S Ly; Jennifer M Miller; Ann J Barbier; Pascal Bonaventure; Jamin D Boggs; Sandy J Wilson; Kirsten L Miller; Brian Lord; Heather M McAllister; D J Tognarelli; Jiejun Wu; Marta C Abad; Carsten Schubert; Timothy W Lovenberg; Nicholas I Carruthers
Novel tetrahydroisoquinolines are histamine H3 antagonists and serotonin reuptake inhibitors.
Bioorganic & medicinal chemistry letters 2007;17(4):1047-51.
2005: Devin M Swanson; Adrienne E Dubin; Chandra Shah; Nadia Nasser; Leon Chang; Scott L Dax; Michele C Jetter; J Guy Breitenbucher; Changlu Liu; Curt Mazur; Brian Lord; Lisa Gonzales; Kenway Hoey; Michele Rizzolio; Michael Bogenstaetter; Ellen E Codd; Doo H Lee; Sui-Po Zhang; Sandra R Chaplan; Nicholas I Carruthers
Identification and biological evaluation of 4-(3-trifluoromethylpyridin-2-yl)piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl)amide, a high affinity TRPV1 (VR1) vanilloid receptor antagonist.
Journal of medicinal chemistry 2005;48(6):1857-72.
2004: Ann J Barbier; C Berridge; Christine Dugovic; Aaron D Laposky; Sandy J Wilson; Jamin D Boggs; Leah Aluisio; Brian Lord; Curt Mazur; Cindy Pudiak; Xavier Langlois; Wei Xiao; Richard Apodaca; Nicholas I Carruthers; Timothy W Lovenberg
Acute wake-promoting actions of JNJ-5207852, a novel, diamine-based H3 antagonist.
British journal of pharmacology 2004;143(5):649-61.
2004: Pascal Bonaventure; Diane Nepomuceno; Curt Mazur; Brian Lord; Dale A Rudolph; JIll Jablonowski; Nicholas I Carruthers; Timothy W Lovenberg
Characterization of N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyano-phenyl)-N-[1-(2-cyclopentyl-ethyl)-piperidin-4yl]acrylamide (JNJ-5207787), a small molecule antagonist of the neuropeptide Y Y2 receptor.
The Journal of pharmacology and experimental therapeutics 2004;308(3):1130-7.