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James Lorens

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Emmet McCormack; David R Micklem; Tina Pavlin; Elisabeth Silden; Richard M West; Michael E Cooper; Bengt Erik Haug; James B Lorens; Bjørn Tore Gjertsen
Nitroreductase, a near-infrared reporter platform for in vivo time-domain optical imaging of metastatic cancer.
Jan Roger Olsen; Anne Margrete Oyan; Kari Rostad; Varda Rotter; Xi-Song Ke; Lisha Li; Biaoyang Lin; Jie Liu; James B Lorens; David R Micklem; Hallvard Haugen; Margrete R Hellem; Karl-Henning Kalland
p63 Attenuates Epithelial to Mesenchymal Potential in an Experimental Prostate Cell Model.
Aase M Raddum; Lasse Evensen; Ann Kari Grindheim; Hanne Hollås; James B Lorens; Anni Vedeler
Domains I and IV of Annexin A2 Affect the Formation and Integrity of In Vitro Capillary-Like Networks.

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2013: Emmet McCormack; David R Micklem; Tina Pavlin; Elisabeth Silden; Richard M West; Michael E Cooper; Bengt Erik Haug; James B Lorens; Bjørn Tore Gjertsen
Nitroreductase, a near-infrared reporter platform for in vivo time-domain optical imaging of metastatic cancer.
Cancer research 2013;73(4):1276-86.
2013: Jan Roger Olsen; Anne Margrete Oyan; Kari Rostad; Varda Rotter; Xi-Song Ke; Lisha Li; Biaoyang Lin; Jie Liu; James B Lorens; David R Micklem; Hallvard Haugen; Margrete R Hellem; Karl-Henning Kalland
p63 Attenuates Epithelial to Mesenchymal Potential in an Experimental Prostate Cell Model.
PloS one 2013;8(5):e62547.
2013: Aase M Raddum; Lasse Evensen; Ann Kari Grindheim; Hanne Hollås; James B Lorens; Anni Vedeler
Domains I and IV of Annexin A2 Affect the Formation and Integrity of In Vitro Capillary-Like Networks.
PloS one 2013;8(3):e60281.
2013: Lasse Evensen; Wolfgang Link; James B Lorens
Image-based high-throughput screening for inhibitors of angiogenesis.
Methods in molecular biology (Clifton, N.J.) 2013;931():139-51.
2012: Michael S Christodoulou; Daniela Comi; Lisa Dalla Via; Lasse Evensen; Gabriele Fontana; Ornella Gia; James B Lorens; Marisa Martinelli; Stefano Pieraccini; Maurizio Sironi; Valentina Zuco; Franco Zunino; Stella Borrelli; Daniele Passarella
Camptothecin-7-yl-methanthiole: semisynthesis and biological evaluation.
ChemMedChem 2012;7(12):2134-43.
2012: Kimberley Hatfield; James B Lorens; Håkon Reikvam; Lasse Evensen; Oystein Bruserud
Soluble mediators released by acute myeloid leukemia cells increase capillary-like networks.
European journal of haematology 2012;89(6):478-90.
2012: Marco Radi; Silvia Schenone; Claudio Zamperini; Marialessandra Caporicci; Elena Dreassi; Lasse Evensen; Federico Falchi; James B Lorens; Francesca Musumeci; Maurizio Botta
A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: from in silico screening to cyclodextrin formulation.
Bioorganic & medicinal chemistry letters 2012;22(17):5579-83.
2012: Eystein Oveland; Line Wergeland; Bjørn Tore Gjertsen; Randi Hovland; James B Lorens; Kari E Fladmark
Ectopic expression of Flt3 kinase inhibits proliferation and promotes cell death in different human cancer cell lines.
Cell biology and toxicology 2012;28(4):201-12.
2012: Dipak Sapkota; Endre N Vasstrand; James B Lorens; Magnus Blø; Ove Bruland; Daniela Elena Costea; Salah O Ibrahim
S100A14 inhibits proliferation of oral carcinoma derived cells through G1-arrest.
Oral oncology 2012;48(3):219-25.
2012: Torbjorn O Pedersen; Zhe Xing; Ying Xue; Anna L Blois; Michele Cottler-Fox; Inge Fristad; Knut N Leknes; James B Lorens; Kamal Mustafa
Osteogenic stimulatory conditions enhance growth and maturation of endothelial cell microvascular networks in culture with mesenchymal stem cells.
Journal of tissue engineering 2012;3(1):2041731412443236.
2011: Anja Hegen; Anna Blois; Crina E Tiron; Monica Hellesøy; David R Micklem; Jacques E Nor; Lars A Akslen; James B Lorens
Efficient in vivo vascularization of tissue-engineering scaffolds.
Journal of tissue engineering and regenerative medicine 2011;5(4):e52-62.
2011: Karoliina Vuoriluoto; H Haugen; S Kiviluoto; J-P Mpindi; J Nevo; C Gjerdrum; C Tiron; James B Lorens; Johanna Ivaska
Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer.
Oncogene 2011;30(12):1436-48.
2011: Jian Wang; I Daphu; Paal-Henning Pedersen; Hrvoje Miletic; Randi Hovland; Sverre Mork; Rolf Bjerkvig; C Tiron; Emmet McCormack; D Micklem; James B Lorens; heike immervoll; Frits Thorsen
A novel brain metastases model developed in immunodeficient rats closely mimics the growth of metastatic brain tumours in patients.
Neuropathology and applied neurobiology 2011;37(2):189-205.
2010: Christine Gjerdrum; Crina Tiron; Torill Høiby; Ingunn Stefansson; Hallvard Haugen; Tone Sandal; Karin Collett; Shan Li; Emmet McCormack; Bjorn T Gjertsen; David R Micklem; Lars A Akslen; Carlotta Glackin; James B Lorens
Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(3):1124-9.
2010: Lasse Evensen; David R Micklem; Wolfgang Link; James B Lorens
A novel imaging-based high-throughput screening approach to anti-angiogenic drug discovery.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2010;77(1):41-51.
2009: Lasse Evensen; David R Micklem; Anna Blois; Sissel Vik Berge; Niels Aarsaether; Amanda Littlewood-Evans; Jeanette Wood; James B Lorens
Mural cell associated VEGF is required for organotypic vessel formation.
PloS one 2009;4(6):e5798.
2008: Magnus Blø; David R Micklem; James B Lorens
Enhanced gene expression from retroviral vectors.
BMC biotechnology 2008;8():19.
2007: David R Micklem; James B Lorens
RNAi screening for therapeutic targets in human malignancies.
Current pharmaceutical biotechnology 2007;8(6):337-43.
2007: Kai-Ove Skaftnesmo; Lars Prestegarden; David R Micklem; James B Lorens
MicroRNAs in tumorigenesis.
Current pharmaceutical biotechnology 2007;8(6):320-5.
2007: Magnus Blø; Jakob M Bogenberger; Susan E Swift; David R Micklem; James B Lorens
Expanding the spectrum of genetic elements transferable by retroviral vectors.
DNA and cell biology 2007;26(11):773-9.
2007: Magnus Blø; David R Micklem; James B Lorens
Drug target discovery using retroviruses.
Expert opinion on drug discovery 2007;2(10):1285-300.
2007: Emmet McCormack; David R Micklem; Lars-Erik Pindard; Elisabeth Silden; Pascal Gallant; Alexandre Belenkov; James B Lorens; Bjorn T Gjertsen
In vivo optical imaging of acute myeloid leukemia by green fluorescent protein: time-domain autofluorescence decoupling, fluorophore quantification, and localization.
Molecular imaging 2007;6(3):193-204.
2007: Camilla Stapnes; Anne P Døskeland; Kimberley Hatfield; Elisabeth Ersvaer; Anita Ryningen; James B Lorens; Bjorn T Gjertsen; Oystein Bruserud
The proteasome inhibitors bortezomib and PR-171 have antiproliferative and proapoptotic effects on primary human acute myeloid leukaemia cells.
British journal of haematology 2007;136(6):814-28.
2007: Bodil Bjørndal; Line M Myklebust; Ken Roger Rosendal; Frøydis D Myromslien; James B Lorens; Garry Nolan; Ove Bruland; Johan R Lillehaug
RACK1 regulates Ki-Ras-mediated signaling and morphological transformation of NIH 3T3 cells.
International journal of cancer. Journal international du cancer 2007;120(5):961-9.
2005: Yonchu Jenkins; Vadim Markovtsov; Wayne Lang; Poonam Sharma; Denise M Pearsall; Justin Warner; Christian Franci; Betty Huang; Jianing Huang; George C Yam; Joseph P Vistan; Erlina Pali; Jorge Vialard; Michel Janicot; James B Lorens; Donald G Payan; Yasumichi Hitoshi
Critical role of the ubiquitin ligase activity of UHRF1, a nuclear RING finger protein, in tumor cell growth.
Molecular biology of the cell 2005;16(12):5621-9.
2005: Sacha J Holland; Mark J Powell; Christian Franci; Emily W Chan; Annabelle M Friera; Robert E Atchison; John McLaughlin; Susan E Swift; Erlina Pali; George C Yam; Stephen Wong; Joe Lasaga; Mary R Shen; Simon Yu; Weiduan Xu; Yasumichi Hitoshi; Jakob Bogenberger; Jacques E Nor; Donald G Payan; James B Lorens
Multiple roles for the receptor tyrosine kinase axl in tumor formation.
Cancer research 2005;65(20):9294-303.
2004: James B Lorens; Denise M Pearsall; Susan E Swift; Beau Peelle; R Armstrong; Susan D Demo; DA Ferrick; Yasumichi Hitoshi; Donald G Payan; D Anderson
Stable, stoichiometric delivery of diverse protein functions.
Journal of biochemical and biophysical methods 2004;58(2):101-10.
2003: Yasumichi Hitoshi; Tarikere L Gururaja; Denise M Pearsall; Wayne Lang; Poonam Sharma; Betty Huang; Susan M Catalano; John McLaughlin; Erlina Pali; Beau Peelle; Jorge Vialard; Michel Janicot; Walter Wouters; Walter H M L Luyten; Mark K Bennett; Dave C Anderson; Donald G Payan; James B Lorens; Jakob Bogenberger; Susan D Demo
Cellular localization and antiproliferative effect of peptides discovered from a functional screen of a retrovirally delivered random peptide library.
Chemistry & biology 2003;10(10):975-87.
2002: Omar D Perez; Shigemi Kinoshita; Yasumichi Hitoshi; Donald G Payan; Toshio Kitamura; Garry P Nolan; James B Lorens
Activation of the PKB/AKT pathway by ICAM-2.
Immunity 2002;16(1):51-65.
2001: James B Lorens; C Sousa; Mark K Bennett; Susan M Molineaux; Donald G Payan
The use of retroviruses as pharmaceutical tools for target discovery and validation in the field of functional genomics.
Current opinion in biotechnology 2001;12(6):613-21.
2001: Beau Peelle; James B Lorens; Weiqun Li; Jakob Bogenberger; Donald G Payan; Dave C Anderson
Intracellular protein scaffold-mediated display of random peptide libraries for phenotypic screens in mammalian cells.
Chemistry & biology 2001;8(5):521-34.
2001: X Xu; C Leo; Y Jang; E Chan; D Padilla; Betty C B Huang; T Lin; Tarikere L Gururaja; Yasumichi Hitoshi; James B Lorens; DC Anderson; B Sikic; Y Luo; Donald G Payan; G P Nolan
Dominant effector genetics in mammalian cells.
Nature genetics 2001;27(1):23-9.
2000: James B Lorens; Y Jang; Alexander B Rossi; Donald G Payan; Jakob Bogenberger
Optimization of regulated LTR-mediated expression.
Virology 2000;272(1):7-15.
2000: James B Lorens; Mark K Bennett; Denise M Pearsall; W R Throndset; Alexander B Rossi; RJ Armstrong; B P Fox; E H Chan; Ying Luo; Esteban S Masuda; DA Ferrick; Dave C Anderson; Donald G Payan; Garry P Nolan
Retroviral delivery of peptide modulators of cellular functions.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;1(5 Pt 1):438-47.
1999: Bjarte Håvik; E Ragnhildstveit; James B Lorens; K Saelemyr; O Fauske; L K Knudsen; Anders Fjose
A novel paired domain DNA recognition motif can mediate Pax2 repression of gene transcription.
Biochemical and biophysical research communications 1999;266(2):532-41.
1999: Susan D Demo; Esteban S Masuda; Alexander B Rossi; B T Throndset; A L Gerard; E H Chan; RJ Armstrong; B P Fox; James B Lorens; Donald G Payan; Richard H Scheller; J M Fisher
Quantitative measurement of mast cell degranulation using a novel flow cytometric annexin-V binding assay.
Cytometry 1999;36(4):340-8.
1998: Yasumichi Hitoshi; James B Lorens; S I Kitada; J Fisher; Mark A LaBarge; HZ Ring; Uta Francke; J C Reed; Shigemi Kinoshita; Garry P Nolan
Toso, a cell surface, specific regulator of Fas-induced apoptosis in T cells.
Immunity 1998;8(4):461-71.
1997: Michael K Shaw; James B Lorens; A Dhawan; R DalCanto; Harley Y Tse; A B Tran; C Bonpane; S L Eswaran; S Brocke; N Sarvetnick; Lawrence Steinman; Garry P Nolan; C Garrison Fathman
Local delivery of interleukin 4 by retrovirus-transduced T lymphocytes ameliorates experimental autoimmune encephalomyelitis.
The Journal of experimental medicine 1997;185(9):1711-4.