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Philip Lorenzi

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Philip L Lorenzi; Christopher P Landowski; Andrea Brancale; Xueqin Song; Leroy B Townsend; John C Drach; Gordon L Amidon
N-methylpurine DNA glycosylase and 8-oxoguanine dna glycosylase metabolize the antiviral nucleoside 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole.
Christopher P Landowski; Philip L Lorenzi; Xueqin Song; Gordon L Amidon
Nucleoside ester prodrug substrate specificity of liver carboxylesterase.
Christopher P Landowski; Xueqin Song; Philip L Lorenzi; John M Hilfinger; Gordon L Amidon
Floxuridine amino acid ester prodrugs: enhancing Caco-2 permeability and resistance to glycosidic bond metabolism.

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2006: Philip L Lorenzi; Christopher P Landowski; Andrea Brancale; Xueqin Song; Leroy B Townsend; John C Drach; Gordon L Amidon
N-methylpurine DNA glycosylase and 8-oxoguanine dna glycosylase metabolize the antiviral nucleoside 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(6):1070-7.
2006: Christopher P Landowski; Philip L Lorenzi; Xueqin Song; Gordon L Amidon
Nucleoside ester prodrug substrate specificity of liver carboxylesterase.
The Journal of pharmacology and experimental therapeutics 2006;316(2):572-80.
2005: Christopher P Landowski; Xueqin Song; Philip L Lorenzi; John M Hilfinger; Gordon L Amidon
Floxuridine amino acid ester prodrugs: enhancing Caco-2 permeability and resistance to glycosidic bond metabolism.
Pharmaceutical research 2005;22(9):1510-8.
2005: Philip L Lorenzi; Christopher P Landowski; Xueqin Song; Katherine Z Borysko; Julie M Breitenbach; Jae Seung Kim; John M Hilfinger; Leroy B Townsend; John C Drach; Gordon L Amidon
Amino acid ester prodrugs of 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole enhance metabolic stability in vitro and in vivo.
The Journal of pharmacology and experimental therapeutics 2005;314(2):883-90.
2005: Xueqin Song; Philip L Lorenzi; Christopher P Landowski; Balvinder S Vig; John M Hilfinger; Gordon L Amidon
Amino acid ester prodrugs of the anticancer agent gemcitabine: synthesis, bioconversion, metabolic bioevasion, and hPEPT1-mediated transport.
Molecular pharmaceutics 2005;2(2):157-67.
2005: Xueqin Song; Balvinder S Vig; Philip L Lorenzi; John C Drach; Leroy B Townsend; Gordon L Amidon
Amino acid ester prodrugs of the antiviral agent 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole as potential substrates of hPEPT1 transporter.
Journal of medicinal chemistry 2005;48(4):1274-7.