Username

Password

Forgot Password?

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Joseph Loscalzo

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Anatomy

Physiology

Platelet Aggregation

Disorders

Living Beings

Sign-in to see full Profile

Network (preview)

Co-Publications
Name
25
Keaney, John
24
Stamler, Jonathan
21
Handy, Diane
20
Leopold, Jane
13
Freedman, Jane
13
Voetsch, Barbara
13
Welch, GN
12
Vita, Joseph
11
Upchurch Jr, Gilbert
10
Zhang, Ying-Yi
10
Simon, Daniel
9
Scribner, Anne
7
Valeri, Robert
7
Heydrick, Stanley
7
Inbal, Aida

Sign-in to see all Coauthors

Publications

TOP 3
Loscalzo Joseph
Homocysteine-mediated thrombosis and angiostasis in vascular pathobiology.
Chan Stephen Y; Zhang Ying-Yi; Hemann Craig; Mahoney Christopher E; Zweier Jay L; Loscalzo Joseph
MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2.
Wolpin Brian M; Weller Peter F; Katz Joel T; Levy Bruce D; Loscalzo Joseph
Clinical problem-solving. The writing on the wall.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Joseph Loscalzo (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Loscalzo Joseph
Homocysteine-mediated thrombosis and angiostasis in vascular pathobiology.
The Journal of clinical investigation 2009;119(11):3203-5.
2009: Chan Stephen Y; Zhang Ying-Yi; Hemann Craig; Mahoney Christopher E; Zweier Jay L; Loscalzo Joseph
MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2.
Cell metabolism 2009;10(4):273-84.
2009: Wolpin Brian M; Weller Peter F; Katz Joel T; Levy Bruce D; Loscalzo Joseph
Clinical problem-solving. The writing on the wall.
The New England journal of medicine 2009;361(14):1387-92.
2009: Jahangir Eiman; Vita Joseph A; Handy Diane; Holbrook Monica; Palmisano Joseph; Beal Ryan; Loscalzo Joseph; Eberhardt Robert T
The effect of L-arginine and creatine on vascular function and homocysteine metabolism.
Vascular medicine (London, England) 2009;14(3):239-48.
2009: Bitton Asaf; Yialamas Maria; Levy Bruce D; Katz Joel T; Loscalzo Joseph
Clinical problem-solving. A fragile balance.
The New England journal of medicine 2009;361(1):74-9.
2009: Ottaviano Filomena G; Tang Shiow-Shih; Handy Diane E; Loscalzo Joseph
Regulation of the extracellular antioxidant selenoprotein plasma glutathione peroxidase (GPx-3) in mammalian cells.
Molecular and cellular biochemistry 2009;327(1-2):111-26.
2009: Handy Diane E; Lubos Edith; Yang Yi; Galbraith John D; Kelly Neil; Zhang Ying-Yi; Leopold Jane A; Loscalzo Joseph
Glutathione peroxidase-1 regulates mitochondrial function to modulate redox-dependent cellular responses.
The Journal of biological chemistry 2009;284(18):11913-21.
2009: Qin Xuebin; Hu Weiguo; Song Wenping; Blair Price; Wu Gongxiong; Hu Xuemei; Song Yanli; Bauer Selena; Feelisch Martin; Leopold Jane A; Loscalzo Joseph; Halperin Jose A
Balancing role of nitric oxide in complement-mediated activation of platelets from mCd59a and mCd59b double-knockout mice.
American journal of hematology 2009;84(4):221-7.
2009: Maron Bradley A; Zhang Ying-Yi; Handy Diane E; Beuve Annie; Tang Shiow-Shih; Loscalzo Joseph; Leopold Jane A
Aldosterone increases oxidant stress to impair guanylyl cyclase activity by cysteinyl thiol oxidation in vascular smooth muscle cells.
The Journal of biological chemistry 2009;284(12):7665-72.
2009: Maron Bradley A; Loscalzo Joseph
The treatment of hyperhomocysteinemia.
Annual review of medicine 2009;60():39-54.
2008: Schnabel Renate; Lubos Edith; Messow Claudia M; Sinning Christoph R; Zeller Tanja; Wild Philipp S; Peetz Dirk; Handy Diane E; Munzel Thomas; Loscalzo Joseph; Lackner Karl J; Blankenberg Stefan
Selenium supplementation improves antioxidant capacity in vitro and in vivo in patients with coronary artery disease The SElenium Therapy in Coronary Artery disease Patients (SETCAP) Study.
American heart journal 2008;156(6):1201.e1-11.
2008: Loscalzo Joseph
Membrane redox state and apoptosis: death by peroxide.
Cell metabolism 2008;8(3):182-3.
2008: Sung Anthony D; Cheng Susan; Moslehi Javid; Scully Eileen P; Prior Jason M; Loscalzo Joseph
Hepatocellular carcinoma with intracavitary cardiac involvement: a case report and review of the literature.
The American journal of cardiology 2008;102(5):643-5.
2008: Blicharz Timothy M; Rissin David M; Bowden Michaela; Hayman Ryan B; DiCesare Christopher; Bhatia Jasvinder S; Grand-Pierre Nerline; Siqueira Walter L; Helmerhorst Eva J; Loscalzo Joseph; Oppenheim Frank G; Walt David R
Use of colorimetric test strips for monitoring the effect of hemodialysis on salivary nitrite and uric acid in patients with end-stage renal disease: a proof of principle.
Clinical chemistry 2008;54(9):1473-80.
2008: Song Yanli; Coleman Laura; Shi Jianru; Beppu Hideyuki; Sato Kaori; Walsh Kenneth; Loscalzo Joseph; Zhang Ying-Yi
Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice.
American journal of physiology. Heart and circulatory physiology 2008;295(2):H677-90.
2008: Pitt Bertram; Loscalzo Joseph; Ycas Joseph; Raichlen Joel S
Lipid levels after acute coronary syndromes.
Journal of the American College of Cardiology 2008;51(15):1440-5.
2008: Voetsch Barbara; Jin Richard C; Bierl Charlene; Deus-Silva Leonardo; Camargo Erica C S; Annichino-Bizacchi Joyce M; Handy Diane E; Loscalzo Joseph
Role of promoter polymorphisms in the plasma glutathione peroxidase (GPx-3) gene as a risk factor for cerebral venous thrombosis.
Stroke; a journal of cerebral circulation 2008;39(2):303-7.
2008: Loscalzo Joseph; Tomaselli Gordon F; Vaughan Douglas E; Walsh Richard A
Task force 7: training in cardiovascular research.
Journal of the American College of Cardiology 2008;51(3):380-3.
2008: Ottaviano Filomena G; Handy Diane E; Loscalzo Joseph
Redox regulation in the extracellular environment.
Circulation journal : official journal of the Japanese Circulation Society 2008;72(1):1-16.
2008: Chan Stephen Y; Loscalzo Joseph
Pathogenic mechanisms of pulmonary arterial hypertension.
Journal of molecular and cellular cardiology 2008;44(1):14-30.
2008: Lubos Edith; Handy Diane E; Loscalzo Joseph
Role of oxidative stress and nitric oxide in atherothrombosis.
Frontiers in bioscience : a journal and virtual library 2008;13():5323-44.
2007: Sebastian Jodi K; Voetsch Barbara; Stone John H; Romay-Penabad Zurina; Lo Grace H; Allen Nancy B; Davis John C; Hoffman Gary S; McCune W Joseph; St Clair E William; Specks Ulrich; Spiera Robert; Loscalzo Joseph; Pierangeli Silvia; Merkel Peter A;
The frequency of anticardiolipin antibodies and genetic mutations associated with hypercoagulability among patients with Wegener's granulomatosis with and without history of a thrombotic event.
The Journal of rheumatology 2007;34(12):2446-50.
2007: Maron Bradley A; Loscalzo Joseph
Should hyperhomocysteinemia be treated in patients with atherosclerotic disease?
Current atherosclerosis reports 2007;9(5):375-83.
2007: Letts Gordon; Loscalzo Joseph
Frontiers in nephrology: targeting inflammation using novel nitric oxide donors.
Journal of the American Society of Nephrology : JASN 2007;18(11):2863-9.
2007: Lubos Edith; Loscalzo Joseph; Handy Diane E
Homocysteine and glutathione peroxidase-1.
Antioxidants & redox signaling 2007;9(11):1923-40.
2007: Loscalzo Joseph
Association studies in an era of too much information: clinical analysis of new biomarker and genetic data.
Circulation 2007;116(17):1866-70.
2007: Rajasekaran Namakkal S; Connell Patrice; Christians Elisabeth S; Yan Liang-Jun; Taylor Ryan P; Orosz András; Zhang Xiu Q; Stevenson Tamara J; Peshock Ronald M; Leopold Jane A; Barry William H; Loscalzo Joseph; Odelberg Shannon J; Benjamin Ivor J
Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice.
Cell 2007;130(3):427-39.
2007: Biolo Andreia; Chao Tania; Duhaney Toni-Ann S; Kotlyar Eugene; Allensworth-Davies Donald; Loscalzo Joseph; Sam Flora
Usefulness of the aldosterone synthase gene polymorphism C-344-T to predict cardiac remodeling in African-Americans versus non-African-Americans with chronic systolic heart failure.
The American journal of cardiology 2007;100(2):285-90.
2007: Yang Yi; Song Yanli; Loscalzo Joseph
Regulation of the protein disulfide proteome by mitochondria in mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(26):10813-7.
2007: Loscalzo Joseph
Entrepreneurship in the medical academy: possibilities and challenges in commercialization of research discoveries.
Circulation 2007;115(12):1504-7.
2007: Leopold Jane A; Dam Aamir; Maron Bradley A; Scribner Anne W; Liao Ronglih; Handy Diane E; Stanton Robert C; Pitt Bertram; Loscalzo Joseph
Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity.
Nature medicine 2007;13(2):189-97.
2007: Voetsch Barbara; Jin Richard C; Bierl Charlene; Benke Kelly S; Kenet Gili; Simioni Paolo; Ottaviano Filomena; Damasceno Benito P; Annichino-Bizacchi Joyce M; Handy Diane E; Loscalzo Joseph
Promoter polymorphisms in the plasma glutathione peroxidase (GPx-3) gene: a novel risk factor for arterial ischemic stroke among young adults and children.
Stroke; a journal of cerebral circulation 2007;38(1):41-9.
2007: Loscalzo Joseph; Kohane Isaac; Barabasi Albert-Laszlo
Human disease classification in the postgenomic era: a complex systems approach to human pathobiology.
Molecular systems biology 2007;3():124.
2007: Dardik Rima; Krapp Tanya; Rosenthal Esther; Loscalzo Joseph; Inbal Aida
Effect of FXIII on monocyte and fibroblast function.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2007;19(1-4):113-20.
2006: Sam Flora; Halickman Isaac; Vita Joseph A; Levitzky Yamini; Cupples L Adrienne; Loscalzo Joseph; Allensworth-Davies Donald
Predictors of improved left ventricular systolic function in an urban cardiomyopathy program.
The American journal of cardiology 2006;98(12):1622-6.
2006: Johnson Rebecca C; Leopold Jane A; Loscalzo Joseph
Vascular calcification: pathobiological mechanisms and clinical implications.
Circulation research 2006;99(10):1044-59.
2006: Maron Bradley A; Loscalzo Joseph
Homocysteine.
Clinics in laboratory medicine 2006;26(3):591-609, vi.
2006: Maitland Karlene; Bridges Lakeesha; Davis Wendell P; Loscalzo Joseph; Pointer Mildred A
Different effects of angiotensin receptor blockade on end-organ damage in salt-dependent and salt-independent hypertension.
Circulation 2006;114(9):905-11.
2006: Handy Diane E; Loscalzo Joseph
Nitric oxide and posttranslational modification of the vascular proteome: S-nitrosation of reactive thiols.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(6):1207-14.
2006: Loscalzo Joseph
The NIH budget and the future of biomedical research.
The New England journal of medicine 2006;354(16):1665-7.
2006: Loscalzo Joseph
Joseph Loscalzo, MD, PhD: a conversation with the Editor. Interview by William Clifford Roberts.
The American journal of cardiology 2006;97(7):1110-22.
2006: Loscalzo Joseph
Homocysteine trials--clear outcomes for complex reasons.
The New England journal of medicine 2006;354(15):1629-32.
2006: Matsui Reiko; Xu Shanqin; Maitland Karlene A; Mastroianni Roberto; Leopold Jane A; Handy Diane E; Loscalzo Joseph; Cohen Richard A
Glucose-6-phosphate dehydrogenase deficiency decreases vascular superoxide and atherosclerotic lesions in apolipoprotein E(-/-) mice.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(4):910-6.
2006: Dardik Rima; Leor Jonathan; Skutelsky Ehud; Castel David; Holbova Radka; Schiby Ginette; Shaish Aviv; Dickneite Gerhard; Loscalzo Joseph; Inbal Aida
Evaluation of the pro-angiogenic effect of factor XIII in heterotopic mouse heart allografts and FXIII-deficient mice.
Thrombosis and haemostasis 2006;95(3):546-50.
2006: Robbins I M; Kawut S M; Yung D; Reilly M P; Lloyd W; Cunningham G; Loscalzo J; Kimmel S E; Christman B W; Barst R J
A study of aspirin and clopidogrel in idiopathic pulmonary arterial hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2006;27(3):578-84.
2006: Galasso Gennaro; Schiekofer Stephan; Sato Kaori; Shibata Rei; Handy Diane E; Ouchi Noriyuki; Leopold Jane A; Loscalzo Joseph; Walsh Kenneth
Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction.
Circulation research 2006;98(2):254-61.
2006: Handy Diane E; Hang Gaozhen; Scolaro John; Metes Nicole; Razaq Nadia; Yang Yi; Loscalzo Joseph
Aminoglycosides decrease glutathione peroxidase-1 activity by interfering with selenocysteine incorporation.
The Journal of biological chemistry 2006;281(6):3382-8.
2006: Ruberg Frederick L; Viereck Jason; Phinikaridou Alkystis; Qiao Ye; Loscalzo Joseph; Hamilton James A
Identification of cholesteryl esters in human carotid atherosclerosis by ex vivo image-guided proton MRS.
Journal of lipid research 2006;47(2):310-7.
2006: Kamath Atul F; Chauhan Anil K; Kisucka Janka; Dole Vandana S; Loscalzo Joseph; Handy Diane E; Wagner Denisa D
Elevated levels of homocysteine compromise blood-brain barrier integrity in mice.
Blood 2006;107(2):591-3.
2006: Dardik R; Loscalzo J; Inbal A
Factor XIII (FXIII) and angiogenesis.
Journal of thrombosis and haemostasis : JTH 2006;4(1):19-25.
2006: Raiesdana Azad; Loscalzo Joseph
Pulmonary arterial hypertension.
Annals of medicine 2006;38(2):95-110.
2005: Loscalzo Joseph
Clinical trials in cardiovascular medicine in an era of marginal benefit, bias, and hyperbole.
Circulation 2005;112(20):3026-9.
2005: Antman Elliott M; DeMets David; Loscalzo Joseph
Cyclooxygenase inhibition and cardiovascular risk.
Circulation 2005;112(5):759-70.
2005: Song Yanli; Jones John E; Beppu Hideyuki; Keaney John F; Loscalzo Joseph; Zhang Ying-Yi
Increased susceptibility to pulmonary hypertension in heterozygous BMPR2-mutant mice.
Circulation 2005;112(4):553-62.
2005: Matsui Reiko; Xu Shanqin; Maitland Karlene A; Hayes Antoinette; Leopold Jane A; Handy Diane E; Loscalzo Joseph; Cohen Richard A
Glucose-6 phosphate dehydrogenase deficiency decreases the vascular response to angiotensin II.
Circulation 2005;112(2):257-63.
2005: Leopold Jane A; Loscalzo Joseph
Oxidative enzymopathies and vascular disease.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(7):1332-40.
2005: Jin Richard C; Voetsch Barbara; Loscalzo Joseph
Endogenous mechanisms of inhibition of platelet function.
Microcirculation (New York, N.Y. : 1994) 2005;12(3):247-58.
2005: Zhang Yufeng; Handy Diane E; Loscalzo Joseph
Adenosine-dependent induction of glutathione peroxidase 1 in human primary endothelial cells and protection against oxidative stress.
Circulation research 2005;96(8):831-7.
2005: Handy Diane E; Zhang Yufeng; Loscalzo Joseph
Homocysteine down-regulates cellular glutathione peroxidase (GPx1) by decreasing translation.
The Journal of biological chemistry 2005;280(16):15518-25.
2005: Loscalzo Joseph; Voetsch Barbara; Liao Ronglih; Leopold Jane
Genetic determinants of vascular oxidant stress and endothelial dysfunction.
Congestive heart failure (Greenwich, Conn.) 2005;11(2):73-9.
2005: Benjamin Ivor J; Arnett Donna K; Loscalzo Joseph;
Discovering the full spectrum of cardiovascular disease: Minority Health Summit 2003: report of the Basic Science Writing Group.
Circulation 2005;111(10):e120-3.
2005: Dardik Rima; Loscalzo Joseph; Eskaraev Regina; Inbal Aida
Molecular mechanisms underlying the proangiogenic effect of factor XIII.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(3):526-32.
2005: Yang Yi; Loscalzo Joseph
S-nitrosoprotein formation and localization in endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(1):117-22.
2004: Handy D E; Scolaro J; Chen J; Huang P; Loscalzo J
L-arginine increases plasma homocysteine in apoE-/-/iNOS-/- double knockout mice.
Cellular and molecular biology (Noisy-le-Grand, France) 2004;50(8):903-9.
2004: Loscalzo Joseph; Bonow Robert O; Jacobs Alice K
Coronary calcium screening and the American Heart Association news embargo.
Circulation 2004;110(23):3504-5.
2004: Jacobs Alice K; Smith Sidney C; Popp Richard L; Loscalzo Joseph
Ethics and professionalism: can there be consensus? An editorial comment on the report of the ACCF/AHA Consensus Conference on Professionalism and Ethics.
Circulation 2004;110(16):2278-9.
2004: Farber Harrison W; Loscalzo Joseph
Pulmonary arterial hypertension.
The New England journal of medicine 2004;351(16):1655-65.
2004: Loscalzo Joseph
L-arginine and atherothrombosis.
The Journal of nutrition 2004;134(10 Suppl):2798S-2800S; discussion 2818S-2819S.
2004: Voetsch Barbara; Jin Richard C; Loscalzo Joseph
Nitric oxide insufficiency and atherothrombosis.
Histochemistry and cell biology 2004;122(4):353-67.
2004: Faxon David P; Fuster Valentin; Libby Peter; Beckman Joshua A; Hiatt William R; Thompson Robert W; Topper James N; Annex Brian H; Rundback John H; Fabunmi Rosalind P; Robertson Rose Marie; Loscalzo Joseph;
Atherosclerotic Vascular Disease Conference: Writing Group III: pathophysiology.
Circulation 2004;109(21):2617-25.
2004: Faxon David P; Creager Mark A; Smith Sidney C; Pasternak Richard C; Olin Jeffrey W; Bettmann Michael A; Criqui Michael H; Milani Richard V; Loscalzo Joseph; Kaufman John A; Jones Daniel W; Pearce William H;
Atherosclerotic Vascular Disease Conference: Executive summary: Atherosclerotic Vascular Disease Conference proceeding for healthcare professionals from a special writing group of the American Heart Association.
Circulation 2004;109(21):2595-604.
2004: Bierl Charlene; Voetsch Barbara; Jin Richard C; Handy Diane E; Loscalzo Joseph
Determinants of human plasma glutathione peroxidase (GPx-3) expression.
The Journal of biological chemistry 2004;279(26):26839-45.
2004: Morel Nicole M; Holland Joanne M; van der Greef Jan; Marple Edward W; Clish Clary; Loscalzo Joseph; Naylor Stephen
Primer on medical genomics. Part XIV: Introduction to systems biology--a new approach to understanding disease and treatment.
Mayo Clinic proceedings. Mayo Clinic 2004;79(5):651-8.
2004: Jones John E; Walker Jennifer L; Song Yanli; Weiss Norbert; Cardoso Wellington V; Tuder Rubin M; Loscalzo Joseph; Zhang Ying-Yi
Effect of 5-lipoxygenase on the development of pulmonary hypertension in rats.
American journal of physiology. Heart and circulatory physiology 2004;286(5):H1775-84.
2004: Voetsch Barbara; Loscalzo Joseph
Genetics of thrombophilia: impact on atherogenesis.
Current opinion in lipidology 2004;15(2):129-43.
2004: Napoli Claudio; Loscalzo Joseph
Nitric oxide and other novel therapies for pulmonary hypertension.
Journal of cardiovascular pharmacology and therapeutics 2004;9(1):1-8.
2004: Voetsch Barbara; Benke Kelly S; Panhuysen Carolien I; Damasceno Benito P; Loscalzo Joseph
The combined effect of paraoxonase promoter and coding region polymorphisms on the risk of arterial ischemic stroke among young adults.
Archives of neurology 2004;61(3):351-6.
2004: Heydrick Stanley J; Weiss Norbert; Thomas Shane R; Cap Andre P; Pimentel David R; Loscalzo Joseph; Keaney John F
L-Homocysteine and L-homocystine stereospecifically induce endothelial nitric oxide synthase-dependent lipid peroxidation in endothelial cells.
Free radical biology & medicine 2004;36(5):632-40.
2004: Loscalzo Joseph
Ozone--from environmental pollutant to atherogenic determinant.
The New England journal of medicine 2004;350(8):834-5.
2004: Jain Mohit; Cui Lei; Brenner Daniel A; Wang Bo; Handy Diane E; Leopold Jane A; Loscalzo Joseph; Apstein Carl S; Liao Ronglih
Increased myocardial dysfunction after ischemia-reperfusion in mice lacking glucose-6-phosphate dehydrogenase.
Circulation 2004;109(7):898-903.
2004: Voetsch Barbara; Loscalzo Joseph
Genetic determinants of arterial thrombosis.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(2):216-29.
2004: Walford Geoffrey A; Moussignac Rose-Laure; Scribner Anne W; Loscalzo Joseph; Leopold Jane A
Hypoxia potentiates nitric oxide-mediated apoptosis in endothelial cells via peroxynitrite-induced activation of mitochondria-dependent and -independent pathways.
The Journal of biological chemistry 2004;279(6):4425-32.
2004: Loscalzo Joseph
Stem cells and regeneration of the cardiovascular system: facts, fictions, and uncertainties.
Blood cells, molecules & diseases 2004;32(1):97-9.
2003: Scribner Anne Ward; Loscalzo Joseph; Napoli Claudio
The effect of angiotensin-converting enzyme inhibition on endothelial function and oxidant stress.
European journal of pharmacology 2003;482(1-3):95-9.
2003: Manger William M; Simchon Shlomoh; Stier Charles T; Loscalzo Joseph; Jan Kung-Ming; Jan Rex; Haddy Francis
Protective effects of dietary potassium chloride on hemodynamics of Dahl salt-sensitive rats in response to chronic administration of sodium chloride.
Journal of hypertension 2003;21(12):2305-13.
2003: Weiss Norbert; Heydrick Stanley J; Postea Otilia; Keller Christiane; Keaney John F; Loscalzo Joseph
Influence of hyperhomocysteinemia on the cellular redox state--impact on homocysteine-induced endothelial dysfunction.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2003;41(11):1455-61.
2003: Cohn Jay N; Loscalzo Joseph; Franciosa Joseph A
Nitric oxide's role in heart failure: pathophysiology and treatment. Introduction.
Journal of cardiac failure 2003;9(5 Suppl Nitric Oxide):S197-8.
2003: Loscalzo Joseph
The evolution of the discipline of vascular biology: from systems physiology to molecular biology to molecular systems.
Circulation research 2003;93(7):583-5.
2003: Walford G; Loscalzo J
Nitric oxide in vascular biology.
Journal of thrombosis and haemostasis : JTH 2003;1(10):2112-8.
2003: Eberhardt Robert T; McMahon Lillian; Duffy Stephen J; Steinberg Martin H; Perrine Susan P; Loscalzo Joseph; Coffman Jay D; Vita Joseph A
Sickle cell anemia is associated with reduced nitric oxide bioactivity in peripheral conduit and resistance vessels.
American journal of hematology 2003;74(2):104-11.
2003: Loscalzo J
Oxidant stress: a key determinant of atherothrombosis.
Biochemical Society transactions 2003;31(Pt 5):1059-61.
2003: Leopold J A; Loscalzo J
Organic nitrate tolerance and endothelial dysfunction: role of folate therapy.
Minerva cardioangiologica 2003;51(4):349-59.
2003: Dardik Rima; Solomon Arieh; Loscalzo Joseph; Eskaraev Regina; Bialik Ann; Goldberg Iris; Schiby Ginette; Inbal Aida
Novel proangiogenic effect of factor XIII associated with suppression of thrombospondin 1 expression.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(8):1472-7.
2003: Leopold Jane A; Walker Jennifer; Scribner Anne W; Voetsch Barbara; Zhang Ying-Yi; Loscalzo Alexander J; Stanton Robert C; Loscalzo Joseph
Glucose-6-phosphate dehydrogenase modulates vascular endothelial growth factor-mediated angiogenesis.
The Journal of biological chemistry 2003;278(34):32100-6.
2003: Loscalzo Joseph
Proteomics in cardiovascular biology and medicine.
Circulation 2003;108(4):380-3.
2003: Jain Mohit; Brenner Daniel A; Cui Lei; Lim Chee Chew; Wang Bo; Pimentel David R; Koh Stanley; Sawyer Douglas B; Leopold Jane A; Handy Diane E; Loscalzo Joseph; Apstein Carl S; Liao Ronglih
Glucose-6-phosphate dehydrogenase modulates cytosolic redox status and contractile phenotype in adult cardiomyocytes.
Circulation research 2003;93(2):e9-16.
2003: Forde Patrick; Scribner Anne Ward; Dial Ravina; Loscalzo Joseph; Trolliet María R
Prevention of hypertension and renal dysfunction in Dahl rats by alpha-tocopherol.
Journal of cardiovascular pharmacology 2003;42(1):82-8.
2003: Handy Diane E; Loscalzo Joseph
Homocysteine and atherothrombosis: diagnosis and treatment.
Current atherosclerosis reports 2003;5(4):276-83.
2003: Freedman J E; Loscalzo J
Nitric oxide and its relationship to thrombotic disorders.
Journal of thrombosis and haemostasis : JTH 2003;1(6):1183-8.
2003: Loscalzo Joseph
Functional polymorphisms in a candidate gene for atherothrombosis: unraveling the complex fabric of a polygenic phenotype.
Journal of the American College of Cardiology 2003;41(6):946-8.
2003: Leopold Jane A; Zhang Ying-Yi; Scribner Anne W; Stanton Robert C; Loscalzo Joseph
Glucose-6-phosphate dehydrogenase overexpression decreases endothelial cell oxidant stress and increases bioavailable nitric oxide.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(3):411-7.
2003: Loscalzo Joseph
Adverse effects of supplemental L-arginine in atherosclerosis: consequences of methylation stress in a complex catabolism?
Arteriosclerosis, thrombosis, and vascular biology 2003;23(1):3-5.
2002: Willoughby Scott; Holmes Andrew; Loscalzo Joseph
Platelets and cardiovascular disease.
European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology 2002;1(4):273-88.
2002: Loscalzo Joseph; Balaban Robert; Becker Lance B; Ginsburg Geoffrey S; Hachinski Vladimir C; Hall John E; Heistad Donald D; Leinwand Leslie A; Lenfant Claude J; Marban Eduardo; Olson Eric N; Schwartz Stephen M;
Task Force on Strategic Research Direction: Basic Science Subgroup key science topics report.
Circulation 2002;106(20):e149-61.
2002: Roberts Robert; Bonow Robert O; Loscalzo Joseph; Mosca Lori;
Report of the American Heart Association Task Force on Strategic Research Direction: executive summary.
Circulation 2002;106(20):2630-2.
2002: Napoli Claudio; Lerman Lilach O; de Nigris Filomena; Loscalzo Joseph; Ignarro Louis J
Glycoxidized low-density lipoprotein downregulates endothelial nitricoxide synthase in human coronary cells.
Journal of the American College of Cardiology 2002;40(8):1515-22.
2002: Loscalzo Joseph
Oxidative stress in endothelial cell dysfunction and thrombosis.
Pathophysiology of haemostasis and thrombosis 2002;32(5-6):359-60.
2002: Tawakol Ahmed; Forgione Marc A; Stuehlinger Markus; Alpert Nathaniel M; Cooke John P; Loscalzo Joseph; Fischman Alan J; Creager Mark A; Gewirtz Henry
Homocysteine impairs coronary microvascular dilator function in humans.
Journal of the American College of Cardiology 2002;40(6):1051-58.
2002: Weiss Norbert; Keller Christiane; Hoffmann Ulrich; Loscalzo Joseph
Endothelial dysfunction and atherothrombosis in mild hyperhomocysteinemia.
Vascular medicine (London, England) 2002;7(3):227-39.
2002: Forgione Marc A; Cap Andre; Liao Ronglih; Moldovan Nicanor I; Eberhardt Robert T; Lim Chee Chew; Jones John; Goldschmidt-Clermont Pascal J; Loscalzo Joseph
Heterozygous cellular glutathione peroxidase deficiency in the mouse: abnormalities in vascular and cardiac function and structure.
Circulation 2002;106(9):1154-8.
2002: Kahn David F; Duffy Stephen J; Tomasian Douglas; Holbrook Monika; Rescorl Lynn; Russell Judson; Gokce Noyan; Loscalzo Joseph; Vita Joseph A
Effects of black race on forearm resistance vessel function.
Hypertension 2002;40(2):195-201.
2002: Vita Joseph A; Loscalzo Joseph
Shouldering the risk factor burden: infection, atherosclerosis, and the vascular endothelium.
Circulation 2002;106(2):164-6.
2002: Jones John E; Mendes Lisa; Rudd M Audrey; Russo Giulia; Loscalzo Joseph; Zhang Ying-Yi
Serial noninvasive assessment of progressive pulmonary hypertension in a rat model.
American journal of physiology. Heart and circulatory physiology 2002;283(1):H364-71.
2002: Franciosa Joseph A; Taylor Anne L; Cohn Jay N; Yancy Clyde W; Ziesche Susan; Olukotun Adeoye; Ofili Elizabeth; Ferdinand Keith; Loscalzo Joseph; Worcel Manuel;
African-American Heart Failure Trial (A-HeFT): rationale, design, and methodology.
Journal of cardiac failure 2002;8(3):128-35.
2002: Voetsch Barbara; Benke Kelly S; Damasceno Benito P; Siqueira Lúcia H; Loscalzo Joseph
Paraoxonase 192 Gln-->Arg polymorphism: an independent risk factor for nonfatal arterial ischemic stroke among young adults.
Stroke; a journal of cerebral circulation 2002;33(6):1459-64.
2002: Russo Guilia; Leopold Jane A; Loscalzo Joseph
Vasoactive substances: nitric oxide and endothelial dysfunction in atherosclerosis.
Vascular pharmacology 2002;38(5):259-69.
2002: Freedman Jane E; Loscalzo Joseph
Platelet-monocyte aggregates: bridging thrombosis and inflammation.
Circulation 2002;105(18):2130-2.
2002: Sawyer Douglas B; Loscalzo Joseph
Myocardial hibernation: restorative or preterminal sleep?
Circulation 2002;105(13):1517-9.
2002: Forgione Marc A; Weiss Norbert; Heydrick Stanley; Cap André; Klings Elizabeth S; Bierl Charlene; Eberhardt Robert T; Farber Harrison W; Loscalzo Joseph
Cellular glutathione peroxidase deficiency and endothelial dysfunction.
American journal of physiology. Heart and circulatory physiology 2002;282(4):H1255-61.
2002: Ruberg Frederick L; Leopold Jane A; Loscalzo Joseph
Atherothrombosis: plaque instability and thrombogenesis.
Progress in cardiovascular diseases 2002;44(5):381-94.
2002: Loscalzo Joseph
Homocysteine and dementias.
The New England journal of medicine 2002;346(7):466-8.
2002: Walker Jennifer L; Loscalzo Joseph; Zhang Ying-Yi
5-Lipoxygenase and human pulmonary artery endothelial cell proliferation.
American journal of physiology. Heart and circulatory physiology 2002;282(2):H585-93.
2002: Weiss Norbert; Heydrick Stanley; Zhang Ying-Yi; Bierl Charlene; Cap André; Loscalzo Joseph
Cellular redox state and endothelial dysfunction in mildly hyperhomocysteinemic cystathionine beta-synthase-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(1):34-41.
2002: Ignarro Louis J; Napoli Claudio; Loscalzo Joseph
Nitric oxide donors and cardiovascular agents modulating the bioactivity of nitric oxide: an overview.
Circulation research 2002;90(1):21-8.
2002: Zhang Ying-Yi; Walker Jennifer L; Huang Annong; Keaney John F; Clish Clary B; Serhan Charles N; Loscalzo Joseph
Expression of 5-lipoxygenase in pulmonary artery endothelial cells.
The Biochemical journal 2002;361(Pt 2):267-76.
2002: Ruberg Frederick L; Loscalzo Joseph
Prothrombotic determinants of coronary atherothrombosis.
Vascular medicine (London, England) 2002;7(4):289-99.
2002: Chaves Claudia; Voetsch Barbara; Loscalzo Joseph; Caplan Louis; Chavali Ram
Extensive cerebral venous thrombosis associated with moderate hyperhomocyst(e)inemia and successfully treated with thrombolysis.
Cerebrovascular diseases (Basel, Switzerland) 2002;13(3):214-6.
2001: Gokce N; Holbrook M; Duffy S J; Demissie S; Cupples L A; Biegelsen E; Keaney J F; Loscalzo J; Vita J A
Effects of race and hypertension on flow-mediated and nitroglycerin-mediated dilation of the brachial artery.
Hypertension 2001;38(6):1349-54.
2001: Battinelli E; Willoughby S R; Foxall T; Valeri C R; Loscalzo J
Induction of platelet formation from megakaryocytoid cells by nitric oxide.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(25):14458-63.
2001: Weiss N; Zhang Y Y; Heydrick S; Bierl C; Loscalzo J
Overexpression of cellular glutathione peroxidase rescues homocyst(e)ine-induced endothelial dysfunction.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(22):12503-8.
2001: Loscalzo J
An experiment of nature: genetic L-arginine deficiency and NO insufficiency.
The Journal of clinical investigation 2001;108(5):663-4.
2001: Leopold J A; Cap A; Scribner A W; Stanton R C; Loscalzo J
Glucose-6-phosphate dehydrogenase deficiency promotes endothelial oxidant stress and decreases endothelial nitric oxide bioavailability.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(10):1771-3.
2001: Upchurch G R; Goodman D G; Willoughby S R; Zhang Y Y; Welch G N; Freedman J E; Ye S; Costello C E; Loscalzo J
Heparin reacts with and inactivates nitric oxide.
Journal of cardiovascular pharmacology and therapeutics 2001;6(2):163-73.
2001: Loscalzo J
Nitric oxide insufficiency, platelet activation, and arterial thrombosis.
Circulation research 2001;88(8):756-62.
2001: Trolliet M R; Rudd M A; Loscalzo J
Oxidative stress and renal dysfunction in salt-sensitive hypertension.
Kidney & blood pressure research 2001;24(2):116-23.
2000: Forgione M A; Loscalzo J
Oxidant stress as a critical determinant of endothelial function.
Drug news & perspectives 2000;13(9):523-9.
2000: Forgione M A; Leopold J A; Loscalzo J
Roles of endothelial dysfunction in coronary artery disease.
Current opinion in cardiology 2000;15(6):409-15.
2000: Gurevitz O; Eldar M; Skutelsky E; Tamarin I; Shenkman B; Eskaraev R; Castel D; Loscalzo J; Inbal A
S-nitrosoderivative of a recombinant fragment of von Willebrand factor (S-nitroso-AR545C) inhibits thrombus formation in guinea pig carotid artery thrombosis model.
Thrombosis and haemostasis 2000;84(5):912-7.
2000: Leopold J A; Loscalzo J
Cyclic strain modulates resistance to oxidant stress by increasing G6PDH expression in smooth muscle cells.
American journal of physiology. Heart and circulatory physiology 2000;279(5):H2477-85.
2000: Zhang Y Y; Hammarberg T; Radmark O; Samuelsson B; Ng C F; Funk C D; Loscalzo J
Analysis of a nucleotide-binding site of 5-lipoxygenase by affinity labelling: binding characteristics and amino acid sequences.
The Biochemical journal 2000;351 Pt 3():697-707.
2000: Eberhardt R T; Forgione M A; Cap A; Leopold J A; Rudd M A; Trolliet M; Heydrick S; Stark R; Klings E S; Moldovan N I; Yaghoubi M; Goldschmidt-Clermont P J; Farber H W; Cohen R; Loscalzo J
Endothelial dysfunction in a murine model of mild hyperhomocyst(e)inemia.
The Journal of clinical investigation 2000;106(4):483-91.
2000: Yang Y; Loscalzo J
Regulation of tissue factor expression in human microvascular endothelial cells by nitric oxide.
Circulation 2000;101(18):2144-8.
2000: Leopold J A; Loscalzo J
Clinical importance of understanding vascular biology.
Cardiology in review 2000;8(2):115-23.
2000: Awtry E H; Loscalzo J
Aspirin.
Circulation 2000;101(10):1206-18.
2000: Loscalzo J
Key references: Homocysteine and atherothrombotic vascular disease.
Journal of thrombosis and thrombolysis 2000;9(1):125-6.
2000: Loscalzo J; Freedman J; Inbal A; Keaney J F; Michelson A D; Vita J A
Nitric oxide insufficiency and arterial thrombosis.
Transactions of the American Clinical and Climatological Association 2000;111():158-63.
1999: Hammerman S I; Klings E S; Hendra K P; Upchurch G R; Rishikof D C; Loscalzo J; Farber H W
Endothelial cell nitric oxide production in acute chest syndrome.
The American journal of physiology 1999;277(4 Pt 2):H1579-92.
1999: Maytin M; Leopold J; Loscalzo J
Oxidant stress in the vasculature.
Current atherosclerosis reports 1999;1(2):156-64.
1999: Inbal A; Gurevitz O; Tamarin I; Eskaraev R; Chetrit A; Novicov I; Feldman M; Varon D; Eldar M; Loscalzo J
Unique antiplatelet effects of a novel S-nitrosoderivative of a recombinant fragment of von Willebrand factor, AR545C: in vitro and ex vivo inhibition of platelet function.
Blood 1999;94(5):1693-700.
1999: Rudd M A; Trolliet M; Hope S; Scribner A W; Daumerie G; Toolan G; Cloutier T; Loscalzo J
Salt-induced hypertension in Dahl salt-resistant and salt-sensitive rats with NOS II inhibition.
The American journal of physiology 1999;277(2 Pt 2):H732-9.
1999: Biegelsen E S; Loscalzo J
Endothelial function and atherosclerosis.
Coronary artery disease 1999;10(4):241-56.
1999: Pigazzi A; Heydrick S; Folli F; Benoit S; Michelson A; Loscalzo J
Nitric oxide inhibits thrombin receptor-activating peptide-induced phosphoinositide 3-kinase activity in human platelets.
The Journal of biological chemistry 1999;274(20):14368-75.
1999: Lieberthal W; Fuhro R; Freedman J E; Toolan G; Loscalzo J; Valeri C R
O-raffinose cross-linking markedly reduces systemic and renal vasoconstrictor effects of unmodified human hemoglobin.
The Journal of pharmacology and experimental therapeutics 1999;288(3):1278-87.
1999: Zai A; Rudd M A; Scribner A W; Loscalzo J
Cell-surface protein disulfide isomerase catalyzes transnitrosation and regulates intracellular transfer of nitric oxide.
The Journal of clinical investigation 1999;103(3):393-9.
1999: Bayer R L; Lichtman S M; Allen S L; Budman D R; Buchbinder A; Fetten J; Kolitz J; Loscalzo J
Acquired factor VIII inhibitors--successful treatment with an oral outpatient regimen.
American journal of hematology 1999;60(1):70-1.
1998: Welch G N; Loscalzo J
Homocysteine and atherothrombosis.
The New England journal of medicine 1998;338(15):1042-50.
1998: Liu Z; Rudd M A; Freedman J E; Loscalzo J
S-Transnitrosation reactions are involved in the metabolic fate and biological actions of nitric oxide.
The Journal of pharmacology and experimental therapeutics 1998;284(2):526-34.
1998: Welch G N; Upchurch G R; Farivar R S; Pigazzi A; Vu K; Brecher P; Keaney J F; Loscalzo J
Homocysteine-induced nitric oxide production in vascular smooth-muscle cells by NF-kappa B-dependent transcriptional activation of Nos2.
Proceedings of the Association of American Physicians 1998;110(1):22-31.
1997: Zhao Z; Francis C E; Welch G; Loscalzo J; Ravid K
Reduced glutathione prevents nitric oxide-induced apoptosis in vascular smooth muscle cells.
Biochimica et biophysica acta 1997;1359(2):143-52.
1997: Upchurch G R; Welch G N; Fabian A J; Pigazzi A; Keaney J F; Loscalzo J
Stimulation of endothelial nitric oxide production by homocyst(e)ine.
Atherosclerosis 1997;132(2):177-85.
1997: Freedman J E; Loscalzo J; Barnard M R; Alpert C; Keaney J F; Michelson A D
Nitric oxide released from activated platelets inhibits platelet recruitment.
The Journal of clinical investigation 1997;100(2):350-6.
1997: Upchurch G R; Welch G N; Fabian A J; Freedman J E; Johnson J L; Keaney J F; Loscalzo J
Homocyst(e)ine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxidase.
The Journal of biological chemistry 1997;272(27):17012-7.
1997: Welch G N; Upchurch G R; Loscalzo J
Homocysteine, oxidative stress, and vascular disease.
Hospital practice (1995) 1997;32(6):81-2, 85, 88-92.
1997: Welch G N; Upchurch G; Loscalzo J
Hyperhomocyst(e)inemia and atherothrombosis.
Annals of the New York Academy of Sciences 1997;811():48-58; discussion 58-9.
1997: Upchurch G R; Welch G N; Freedman J E; Fabian A J; Pigazzi A; Scribner A M; Alpert C S; Keaney J F; Loscalzo J
High-dose heparin decreases nitric oxide production by cultured bovine endothelial cells.
Circulation 1997;95(8):2115-21.
1997: Alpert C; Ramdev N; George D; Loscalzo J
Detection of S-nitrosothiols and other nitric oxide derivatives by photolysis-chemiluminescence spectrometry.
Analytical biochemistry 1997;245(1):1-7.
1997: Upchurch G R; Loscalzo J; Banes A J
Changes in the amplitude of cyclic load biphasically modulate endothelial cell DNA synthesis and division.
Vascular medicine (London, England) 1997;2(1):19-24.
1997: Freedman J E; Loscalzo J
Endothelial dysfunction and atherothrombotic occlusive disease.
Drugs 1997;54 Suppl 3():41-9; discussion 49-50.
1996: Dobroski D R; Loscalzo J
Thrombotic risk factors for atherosclerosis.
Coronary artery disease 1996;7(12):919-32.
1996: Keaney J F; Hare J M; Balligand J L; Loscalzo J; Smith T W; Colucci W S
Inhibition of nitric oxide synthase augments myocardial contractile responses to beta-adrenergic stimulation.
The American journal of physiology 1996;271(6 Pt 2):H2646-52.
1996: Freedman J E; Farhat J H; Loscalzo J; Keaney J F
alpha-tocopherol inhibits aggregation of human platelets by a protein kinase C-dependent mechanism.
Circulation 1996;94(10):2434-40.
1996: Michelson A D; Barnard M R; Hechtman H B; MacGregor H; Connolly R J; Loscalzo J; Valeri C R
In vivo tracking of platelets: circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11877-82.
1996: Jackson T S; Lerner E; Weisbrod R M; Tajima M; Loscalzo J; Keaney J F
Vasodilatory properties of recombinant maxadilan.
The American journal of physiology 1996;271(3 Pt 2):H924-30.
1996: Scharfstein J S; Abendschein D R; Eisenberg P R; George D; Cannon C P; Becker R C; Sobel B; Cupples L A; Braunwald E; Loscalzo J
Usefulness of fibrinogenolytic and procoagulant markers during thrombolytic therapy in predicting clinical outcomes in acute myocardial infarction. TIMI-5 Investigators. Thrombolysis in Myocardial Infarction.
The American journal of cardiology 1996;78(5):503-10.
1996: Upchurch G R; Valeri C R; Khuri S F; Rohrer M J; Welch G N; MacGregor H; Ragno G; Francis S; Rodino L J; Michelson A D; Loscalzo J
Effect of heparin on fibrinolytic activity and platelet function in vivo.
The American journal of physiology 1996;271(2 Pt 2):H528-34.
1996: Philippides G J; Loscalzo J
Potential advantages of direct-acting thrombin inhibitors.
Coronary artery disease 1996;7(7):497-507.
1996: Zhang Y Y; Xu A M; Nomen M; Walsh M; Keaney J F; Loscalzo J
Nitrosation of tryptophan residue(s) in serum albumin and model dipeptides. Biochemical characterization and bioactivity.
The Journal of biological chemistry 1996;271(24):14271-9.
1996: Michelson A D; Benoit S E; Furman M I; Breckwoldt W L; Rohrer M J; Barnard M R; Loscalzo J
Effects of nitric oxide/EDRF on platelet surface glycoproteins.
The American journal of physiology 1996;270(5 Pt 2):H1640-8.
1996: Upchurch G R; Welch G N; Loscalzo J
Homocysteine, EDRF, and endothelial function.
The Journal of nutrition 1996;126(4 Suppl):1290S-4S.
1996: Freedman J E; Loscalzo J; Benoit S E; Valeri C R; Barnard M R; Michelson A D
Decreased platelet inhibition by nitric oxide in two brothers with a history of arterial thrombosis.
The Journal of clinical investigation 1996;97(4):979-87.
1996: Upchurch G R; Welch G N; Loscalzo J
The vascular biology of S-nitrosothiols, nitrosated derivatives of thiols.
Vascular medicine (London, England) 1996;1(1):25-33.
1996: Loscalzo J
The macrophage and fibrinolysis.
Seminars in thrombosis and hemostasis 1996;22(6):503-6.
1996: Welch G N; Upchurch G R; Loscalzo J
S-nitrosothiol detection.
Methods in enzymology 1996;268():293-8.
1995: Leopold J A; Loscalzo J
Platelet activation by fibrinolytic agents: a potential mechanism for resistance to thrombolysis and reocclusion after successful thrombolysis.
Coronary artery disease 1995;6(12):923-9.
1995: Marks D S; Vita J A; Folts J D; Keaney J F; Welch G N; Loscalzo J
Inhibition of neointimal proliferation in rabbits after vascular injury by a single treatment with a protein adduct of nitric oxide.
The Journal of clinical investigation 1995;96(6):2630-8.
1995: Khuri S F; Valeri C R; Loscalzo J; Weinstein M J; Birjiniuk V; Healey N A; MacGregor H; Doursounian M; Zolkewitz M A
Heparin causes platelet dysfunction and induces fibrinolysis before cardiopulmonary bypass.
The Annals of thoracic surgery 1995;60(4):1008-14.
1995: Loscalzo J; Welch G
Nitric oxide and its role in the cardiovascular system.
Progress in cardiovascular diseases 1995;38(2):87-104.
1995: Zarich S W; Kowalchuk G J; Weaver W D; Loscalzo J; Sassower M; Manzo K; Byrnes C; Muller J E; Gurewich V
Sequential combination thrombolytic therapy for acute myocardial infarction: results of the Pro-Urokinase and t-PA Enhancement of Thrombolysis (PATENT) Trial.
Journal of the American College of Cardiology 1995;26(2):374-9.
1995: Simon D I; Stamler J S; Loh E; Loscalzo J; Francis S A; Creager M A
Effect of nitric oxide synthase inhibition on bleeding time in humans.
Journal of cardiovascular pharmacology 1995;26(2):339-42.
1995: Loscalzo J; Pasche B; Ouimet H; Freedman J E
Platelets and plasminogen activation.
Thrombosis and haemostasis 1995;74(1):291-3.
1995: Freedman J E; Frei B; Welch G N; Loscalzo J
Glutathione peroxidase potentiates the inhibition of platelet function by S-nitrosothiols.
The Journal of clinical investigation 1995;96(1):394-400.
1995: Levy A P; Levy N S; Loscalzo J; Calderone A; Takahashi N; Yeo K T; Koren G; Colucci W S; Goldberg M A
Regulation of vascular endothelial growth factor in cardiac myocytes.
Circulation research 1995;76(5):758-66.
1995: Freedman J E; Fabian A; Loscalzo J
Impaired EDRF production by endothelial cells exposed to fibrin monomer and FDP.
The American journal of physiology 1995;268(2 Pt 1):C520-6.
1995: Hare J M; Keaney J F; Balligand J L; Loscalzo J; Smith T W; Colucci W S
Role of nitric oxide in parasympathetic modulation of beta-adrenergic myocardial contractility in normal dogs.
The Journal of clinical investigation 1995;95(1):360-6.
1995: Upchurch G R; Welch G N; Loscalzo J
S-nitrosothiols: chemistry, biochemistry, and biological actions.
Advances in pharmacology (San Diego, Calif.) 1995;34():343-9.
1995: Loscalzo J
Endothelial injury, vasoconstriction, and its prevention.
Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital 1995;22(2):180-4.
1994: Loh E; Stamler J S; Hare J M; Loscalzo J; Colucci W S
Cardiovascular effects of inhaled nitric oxide in patients with left ventricular dysfunction.
Circulation 1994;90(6):2780-5.
1994: Slivka A; Chuttani R; Carr-Locke D L; Kobzik L; Bredt D S; Loscalzo J; Stamler J S
Inhibition of sphincter of Oddi function by the nitric oxide carrier S-nitroso-N-acetylcysteine in rabbits and humans.
The Journal of clinical investigation 1994;94(5):1792-8.
1994: Scharfstein J S; Keaney J F; Slivka A; Welch G N; Vita J A; Stamler J S; Loscalzo J
In vivo transfer of nitric oxide between a plasma protein-bound reservoir and low molecular weight thiols.
The Journal of clinical investigation 1994;94(4):1432-9.
1994: Keaney J F; Puyana J C; Francis S; Loscalzo J F; Stamler J S; Loscalzo J
Methylene blue reverses endotoxin-induced hypotension.
Circulation research 1994;74(6):1121-5.
1994: Keaney J F; Puyana J C; Francis S; Loscalzo J F; Stamler J S; Loscalzo J
Methylene blue reverses endotoxin-induced hypotension.
Circulation research 1994;74(6):1121-5.
1994: Simon D I; Ezratty A M; Loscalzo J
The fibrin(ogen)olytic properties of cathepsin D.
Biochemistry 1994;33(21):6555-63.
1994: Keaney J F; Shwaery G T; Xu A; Nicolosi R J; Loscalzo J; Foxall T L; Vita J A
17 beta-estradiol preserves endothelial vasodilator function and limits low-density lipoprotein oxidation in hypercholesterolemic swine.
Circulation 1994;89(5):2251-9.
1994: Welch G; Loscalzo J
Nitric oxide and the cardiovascular system.
Journal of cardiac surgery 1994;9(3):361-71.
1994: Ouimet H; Freedman J E; Loscalzo J
Kinetics and mechanism of platelet-surface plasminogen activation by tissue-type plasminogen activator.
Biochemistry 1994;33(10):2970-6.
1994: Keaney J F; Gaziano J M; Xu A; Frei B; Curran-Celentano J; Shwaery G T; Loscalzo J; Vita J A
Low-dose alpha-tocopherol improves and high-dose alpha-tocopherol worsens endothelial vasodilator function in cholesterol-fed rabbits.
The Journal of clinical investigation 1994;93(2):844-51.
1994: Rabbani L E; Edelman E R; Ganz P; Selwyn A P; Loscalzo J; Bittl J A
Relation of restenosis after excimer laser angioplasty to fasting insulin levels.
The American journal of cardiology 1994;73(5):323-7.
1994: Gaston B; Drazen J M; Jansen A; Sugarbaker D A; Loscalzo J; Richards W; Stamler J S
Relaxation of human bronchial smooth muscle by S-nitrosothiols in vitro.
The Journal of pharmacology and experimental therapeutics 1994;268(2):978-84.
1994: Gaston B; Drazen J M; Loscalzo J; Stamler J S
The biology of nitrogen oxides in the airways.
American journal of respiratory and critical care medicine 1994;149(2 Pt 1):538-51.
1994: Pasche B; Ouimet H; Francis S; Loscalzo J
Structural changes in platelet glycoprotein IIb/IIIa by plasmin: determinants and functional consequences.
Blood 1994;83(2):404-14.
1994: Schaub R G; Bree M P; Hayes L L; Rudd M A; Rabbani L; Loscalzo J; Clinton S K
Recombinant human macrophage colony-stimulating factor reduces plasma cholesterol and carrageenan granuloma foam cell formation in Watanabe heritable hyperlipidemic rabbits.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1994;14(1):70-6.
1994: Rabbani L E; Loscalzo J
Recent observations on the role of hemostatic determinants in the development of the atherothrombotic plaque.
Atherosclerosis 1994;105(1):1-7.
1994: Jaraki O; Strauss W E; Francis S; Loscalzo J; Stamler J S
Antiplatelet effects of a novel antianginal agent, nicorandil.
Journal of cardiovascular pharmacology 1994;23(1):24-30.
1993: Keaney J F; Gaziano J M; Xu A; Frei B; Curran-Celentano J; Shwaery G T; Loscalzo J; Vita J A
Dietary antioxidants preserve endothelium-dependent vessel relaxation in cholesterol-fed rabbits.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(24):11880-4.
1993: Simon D I; Ezratty A M; Francis S A; Rennke H; Loscalzo J
Fibrin(ogen) is internalized and degraded by activated human monocytoid cells via Mac-1 (CD11b/CD18): a nonplasmin fibrinolytic pathway.
Blood 1993;82(8):2414-22.
1993: Lilly C M; Stamler J S; Gaston B; Meckel C; Loscalzo J; Drazen J M
Modulation of vasoactive intestinal peptide pulmonary relaxation by NO in tracheally superfused guinea pig lungs.
The American journal of physiology 1993;265(4 Pt 1):L410-5.
1993: Rabbani L E; Loscalzo J
Atherothrombotic insights into secondary prevention after acute myocardial infarction.
The Canadian journal of cardiology 1993;9(8):739-47.
1993: Lipton S A; Choi Y B; Pan Z H; Lei S Z; Chen H S; Sucher N J; Loscalzo J; Singel D J; Stamler J S
A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds.
Nature 1993;364(6438):626-32.
1993: Loscalzo J
The induction of cellular interactions in atherogenesis and their modulation.
Biochemical Society transactions 1993;21 ( Pt 3)(3):656-9.
1993: Kestin A S; Valeri C R; Khuri S F; Loscalzo J; Ellis P A; MacGregor H; Birjiniuk V; Ouimet H; Pasche B; Nelson M J
The platelet function defect of cardiopulmonary bypass.
Blood 1993;82(1):107-17.
1993: Ouimet H; Loscalzo J
Reciprocating autocatalytic interactions between platelets and the activation system.
Thrombosis research 1993;70(5):355-64.
1993: Simon D I; Stamler J S; Jaraki O; Keaney J F; Osborne J A; Francis S A; Singel D J; Loscalzo J
Antiplatelet properties of protein S-nitrosothiols derived from nitric oxide and endothelium-derived relaxing factor.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(6):791-9.
1993: Rabbani L E; Johnstone M T; Rudd M A; Devine P; George D; Loscalzo J
PPACK attenuates plasmin-induced changes in endothelial integrity.
Thrombosis research 1993;70(6):425-36.
1993: Ezratty A; Simon D I; Loscalzo J
Lipoprotein(a) binds to human platelets and attenuates plasminogen binding and activation.
Biochemistry 1993;32(17):4628-33.
1993: Keaney J F; Simon D I; Stamler J S; Jaraki O; Scharfstein J; Vita J A; Loscalzo J
NO forms an adduct with serum albumin that has endothelium-derived relaxing factor-like properties.
The Journal of clinical investigation 1993;91(4):1582-9.
1993: Cannon C P; Maraganore J M; Loscalzo J; McAllister A; Eddings K; George D; Selwyn A P; Adelman B; Fox I; Braunwald E
Anticoagulant effects of hirulog, a novel thrombin inhibitor, in patients with coronary artery disease.
The American journal of cardiology 1993;71(10):778-82.
1993: Stamler J S; Osborne J A; Jaraki O; Rabbani L E; Mullins M; Singel D; Loscalzo J
Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen.
The Journal of clinical investigation 1993;91(1):308-18.
1992: Loscalzo J
The relation between atherosclerosis and thrombosis.
Circulation 1992;86(6 Suppl):III95-9.
1992: Stamler J S; Singel D J; Loscalzo J
Biochemistry of nitric oxide and its redox-activated forms.
Science (New York, N.Y.) 1992;258(5090):1898-902.
1992: Winther K; Hillegass W; Tofler G H; Jimenez A; Brezinski D A; Schafer A I; Loscalzo J; Williams G H; Muller J E
Effects on platelet aggregation and fibrinolytic activity during upright posture and exercise in healthy men.
The American journal of cardiology 1992;70(11):1051-5.
1992: Loscalzo J
Antiplatelet and antithrombotic effects of organic nitrates.
The American journal of cardiology 1992;70(8):18B-22B.
1992: Stamler J S; Simon D I; Jaraki O; Osborne J A; Francis S; Mullins M; Singel D; Loscalzo J
S-nitrosylation of tissue-type plasminogen activator confers vasodilatory and antiplatelet properties on the enzyme.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(17):8087-91.
1992: Stamler J S; Jaraki O; Osborne J; Simon D I; Keaney J; Vita J; Singel D; Valeri C R; Loscalzo J
Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7674-7.
1992: Scharfstein J; Loscalzo J
Molecular approaches to antithrombotic therapy.
Hospital practice (Office ed.) 1992;27(5):77-86.
1992: Jansen A; Drazen J; Osborne J A; Brown R; Loscalzo J; Stamler J S
The relaxant properties in guinea pig airways of S-nitrosothiols.
The Journal of pharmacology and experimental therapeutics 1992;261(1):154-60.
1992: Rudd M A; George D; Johnstone M T; Moore R T; Collins L; Rabbani L E; Loscalzo J
Effect of thrombin inhibition on the dynamics of thrombolysis and on platelet function during thrombolytic therapy.
Circulation research 1992;70(4):829-34.
1992: Stamler J S; Loscalzo J
Capillary zone electrophoretic detection of biological thiols and their S-nitrosated derivatives.
Analytical chemistry 1992;64(7):779-85.
1992: Stamler J S; Simon D I; Osborne J A; Mullins M E; Jaraki O; Michel T; Singel D J; Loscalzo J
S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(1):444-8.
1992: Loscalzo J; Handin R I
Platelet glycocalicin.
Methods in enzymology 1992;215():289-94.
1992: Stamler J S; Loscalzo J
Endothelium-derived relaxing factor modulates the atherothrombogenic effects of homocysteine.
Journal of cardiovascular pharmacology 1992;20 Suppl 12():S202-4.
1991: Rudd M A; Johnstone M T; Rabbani L E; George D; Ware J A; Loscalzo J
Thrombolytic therapy causes an increase in vascular permeability that is reversed by 1-deamino-8-D-vasopressin.
Circulation 1991;84(6):2568-73.
1991: Kirshenbaum J M; Bahr R D; Flaherty J T; Gurewich V; Levine H J; Loscalzo J; Schumacher R R; Topol E J; Wahr D W; Braunwald E
Clot-selective coronary thrombolysis with low-dose synergistic combinations of single-chain urokinase-type plasminogen activator and recombinant tissue-type plasminogen activator. The Pro-Urokinase for Myocardial Infarction Study Group.
The American journal of cardiology 1991;68(17):1564-9.
1991: Stamler J S; Loscalzo J
The antiplatelet effects of organic nitrates and related nitroso compounds in vitro and in vivo and their relevance to cardiovascular disorders.
Journal of the American College of Cardiology 1991;18(6):1529-36.
1991: Cooke J P; Rossitch E; Andon N A; Loscalzo J; Dzau V J
Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator.
The Journal of clinical investigation 1991;88(5):1663-71.
1991: Newburger J W; Burns J C; Beiser A S; Loscalzo J
Altered lipid profile after Kawasaki syndrome.
Circulation 1991;84(2):625-31.
1991: Simon D I; Fless G M; Scanu A M; Loscalzo J
Tissue-type plasminogen activator binds to and is inhibited by surface-bound lipoprotein(a) and low-density lipoprotein.
Biochemistry 1991;30(27):6671-7.
1991: Ezratty A M; Loscalzo J
New approaches to antiplatelet therapy.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1991;2(2):317-27.
1991: Shaffer J E; Lee F; Thomson S; Han B J; Cooke J P; Loscalzo J
The hemodynamic effects of S-nitrosocaptopril in anesthetized dogs.
The Journal of pharmacology and experimental therapeutics 1991;256(2):704-9.
1990: Johnstone M T; Andrews T; Ware J A; Rudd M A; George D; Weinstein M; Loscalzo J
Bleeding time prolongation with streptokinase and its reduction with 1-desamino-8-D-arginine vasopressin.
Circulation 1990;82(6):2142-51.
1990: Loscalzo J
Regression of coronary atherosclerosis.
The New England journal of medicine 1990;323(19):1337-9.
1990: Mendelsohn M E; O'Neill S; George D; Loscalzo J
Inhibition of fibrinogen binding to human platelets by S-nitroso-N-acetylcysteine.
The Journal of biological chemistry 1990;265(31):19028-34.
1990: Rudd M A; George D; Amarante P; Vaughan D E; Loscalzo J
Temporal effects of thrombolytic agents on platelet function in vivo and their modulation by prostaglandins.
Circulation research 1990;67(5):1175-81.
1990: Cooke J P; Stamler J; Andon N; Davies P F; McKinley G; Loscalzo J
Flow stimulates endothelial cells to release a nitrovasodilator that is potentiated by reduced thiol.
The American journal of physiology 1990;259(3 Pt 2):H804-12.
1990: Loscalzo J
Lipoprotein(a). A unique risk factor for atherothrombotic disease.
Arteriosclerosis (Dallas, Tex.) 1990;10(5):672-9.
1990: Loscalzo J
Molecular biologic modification of plasminogen activators. An artful science.
Circulation 1990;82(3):1062-3.
1990: Creager M A; Cooke J P; Mendelsohn M E; Gallagher S J; Coleman S M; Loscalzo J; Dzau V J
Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans.
The Journal of clinical investigation 1990;86(1):228-34.
1990: Kuo P; Weinfeld M; Loscalzo J
Effect of membrane fatty acyl composition on LDL metabolism in Hep G2 hepatocytes.
Biochemistry 1990;29(28):6626-32.
1990: Loscalzo J
An overview of thrombolytic agents.
Chest 1990;97(4 Suppl):117S-123S.
1990: Loscalzo J; Weinfeld M; Fless G M; Scanu A M
Lipoprotein(a), fibrin binding, and plasminogen activation.
Arteriosclerosis (Dallas, Tex.) 1990;10(2):240-5.
1990: Kuo P; Weinfeld M; Rudd M A; Amarante P; Loscalzo J
Plasma membrane enrichment with cis-unsaturated fatty acids enhances LDL metabolism in U937 monocytes.
Arteriosclerosis (Dallas, Tex.) 1990;10(1):111-8.
1989: Inbal A; Loscalzo J
Glycocalicin binding to von Willebrand factor adsorbed onto collagen-coated or polystyrene surfaces.
Thrombosis research 1989;56(3):347-57.
1989: Kuo P C; Rudd M A; Nicolosi R; Loscalzo J
Effect of dietary fat saturation and cholesterol on low density lipoprotein degradation by mononuclear cells of Cebus monkeys.
Arteriosclerosis (Dallas, Tex.) 1989;9(6):919-27.
1989: Stamler J; Mendelsohn M E; Amarante P; Smick D; Andon N; Davies P F; Cooke J P; Loscalzo J
N-acetylcysteine potentiates platelet inhibition by endothelium-derived relaxing factor.
Circulation research 1989;65(3):789-95.
1989: Stamler J S; Vaughan D E; Loscalzo J
Synergistic disaggregation of platelets by tissue-type plasminogen activator, prostaglandin E1, and nitroglycerin.
Circulation research 1989;65(3):796-804.
1989: Schafer A I; Rodriguez R; Loscalzo J; Gimbrone M A
Inhibition of vascular endothelial cell prostacyclin synthesis by plasmin.
Blood 1989;74(3):1015-20.
1989: Cooke J P; Andon N; Loscalzo J
S-nitrosocaptopril. II. Effects on vascular reactivity.
The Journal of pharmacology and experimental therapeutics 1989;249(3):730-4.
1989: Loscalzo J; Smick D; Andon N; Cooke J
S-nitrosocaptopril. I. Molecular characterization and effects on the vasculature and on platelets.
The Journal of pharmacology and experimental therapeutics 1989;249(3):726-9.
1989: Vaughan D E; Plavin S R; Schafer A I; Loscalzo J
PGE1 accelerates thrombolysis by tissue plasminogen activator.
Blood 1989;73(5):1213-7.
1989: Loscalzo J; Wharton T P; Kirshenbaum J M; Levine H J; Flaherty J T; Topol E J; Ramaswamy K; Kosowsky B D; Salem D N; Ganz P
Clot-selective coronary thrombolysis with pro-urokinase.
Circulation 1989;79(4):776-82.
1989: Stamler J; Whittemore A D; Loscalzo J
Celiac axis compression syndrome caused by sarcoidosis: an acquired form of the syndrome.
The American journal of medicine 1989;86(2):225-7.
1989: Loscalzo J
Thrombolysis in the management of acute myocardial infarction and unstable angina pectoris.
Drugs 1989;37(2):191-204.
1989: Sacks F M; Creager M A; Gallagher S J; Loscalzo J; Dzau V J
Effects of alpha- and beta-adrenergic antagonists on plasma apolipoproteins and forearm blood flow in patients with mild hypertension.
The American journal of medicine 1989;86(1B):8-13.
1988: Stamler J S; Vaughan D E; Rudd M A; Mudge G H; Kirshenbaum J; Young P; Alexander R W; Loscalzo J
Frequency of hypercholesterolemia after cardiac transplantation.
The American journal of cardiology 1988;62(17):1268-72.
1988: Loscalzo J
Structural and kinetic comparison of recombinant human single- and two-chain tissue plasminogen activator.
The Journal of clinical investigation 1988;82(4):1391-7.
1988: Loscalzo J; Braunwald E
Tissue plasminogen activator.
The New England journal of medicine 1988;319(14):925-31.
1988: Stamler J; Cunningham M; Loscalzo J
Reduced thiols and the effect of intravenous nitroglycerin on platelet aggregation.
The American journal of cardiology 1988;62(7):377-80.
1988: Goldhaber S Z; Vaughan D E; Tumeh S S; Loscalzo J
Utility of cross-linked fibrin degradation products in the diagnosis of pulmonary embolism.
American heart journal 1988;116(2 Pt 1):505-8.
1988: Vaughan D E; Kirshenbaum J M; Loscalzo J
Streptokinase-induced, antibody-mediated platelet aggregation: a potential cause of clot propagation in vivo.
Journal of the American College of Cardiology 1988;11(6):1343-8.
1987: Goldhaber S Z; Meyerovitz M F; Markis J E; Kim D; Kessler C M; Sharma G V; Vaughan D E; Selwyn A P; Dawley D L; Loscalzo J
Thrombolytic therapy of acute pulmonary embolism: current status and future potential.
Journal of the American College of Cardiology 1987;10(5 Suppl B):96B-104B.
1987: Loscalzo J; Freedman J; Rudd M A; Barsky-Vasserman I; Vaughan D E
Unsaturated fatty acids enhance low density lipoprotein uptake and degradation by peripheral blood mononuclear cells.
Arteriosclerosis (Dallas, Tex.) 1987;7(5):450-5.
1987: Goldhaber S Z; Markis J E; Kessler C M; Meyerovitz M F; Kim D; Vauchan D E; Selwyn A P; Loscalzo J; Dawley D L; Sharma G V
Perspectives on treatment of acute pulmonary embolism with tissue plasminogen activator.
Seminars in thrombosis and hemostasis 1987;13(2):171-7.
1986: Loscalzo J; Inbal A; Handin R I
von Willebrand protein facilitates platelet incorporation in polymerizing fibrin.
The Journal of clinical investigation 1986;78(4):1112-9.
1985: Adelman B; Michelson A D; Loscalzo J; Greenberg J; Handin R I
Plasmin effect on platelet glycoprotein Ib-von Willebrand factor interactions.
Blood 1985;65(1):32-40.

Sign-in to see more