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Richard Losick
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16
Kolter, Roberto
11
Cutting, Simon
11
Eichenberger, Patrick
9
Rudner, David
9
Stragier, Patrick
8
Kearns, Daniel
7
Fujita, Masaya
7
Ben-Yehuda, Sigal
7
Chu, Frances
6
González-Pastor, José Eduardo
6
Kroos, Lee
6
Ramamurthi, Kumaran
5
Nodwell, JR
5
Moran, Charles
5
Teleman, AA
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All Publications
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2009: López Daniel; Vlamakis Hera; Losick Richard; Kolter Roberto
Cannibalism enhances biofilm development in Bacillus subtilis.
Molecular microbiology 2009;74(3):609-18.
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2009: Ramamurthi Kumaran S; Losick Richard
Negative membrane curvature as a cue for subcellular localization of a bacterial protein.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(32):13541-5.
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2009: López Daniel; Vlamakis Hera; Losick Richard; Kolter Roberto
Paracrine signaling in a bacterium.
Genes & development 2009;23(14):1631-8.
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2009: Rahn-Lee Lilah; Gorbatyuk Boris; Skovgaard Ole; Losick Richard
The conserved sporulation protein YneE inhibits DNA replication in Bacillus subtilis.
Journal of bacteriology 2009;191(11):3736-9.
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2009: Camp Amy H; Losick Richard
A feeding tube model for activation of a cell-specific transcription factor during sporulation in Bacillus subtilis.
Genes & development 2009;23(8):1014-24.
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2009: Chai Yunrong; Kolter Roberto; Losick Richard
A widely conserved gene cluster required for lactate utilization in Bacillus subtilis and its involvement in biofilm formation.
Journal of bacteriology 2009;191(8):2423-30.
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2009: Ramamurthi Kumaran S; Lecuyer Sigolene; Stone Howard A; Losick Richard
Geometric cue for protein localization in a bacterium.
Science (New York, N.Y.) 2009;323(5919):1354-7.
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2009: López Daniel; Fischbach Michael A; Chu Frances; Losick Richard; Kolter Roberto
Structurally diverse natural products that cause potassium leakage trigger multicellularity in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(1):280-5.
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2008: Banse Allison V; Chastanet Arnaud; Rahn-Lee Lilah; Hobbs Errett C; Losick Richard
Parallel pathways of repression and antirepression governing the transition to stationary phase in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(40):15547-52.
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2008: Kain James; He Gina G; Losick Richard
Polar localization and compartmentalization of ClpP proteases during growth and sporulation in Bacillus subtilis.
Journal of bacteriology 2008;190(20):6749-57.
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2008: Ramamurthi Kumaran S; Losick Richard
Grasping at origins.
Cell 2008;134(6):916-8.
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2008: Ramamurthi Kumaran S; Losick Richard
ATP-driven self-assembly of a morphogenetic protein in Bacillus subtilis.
Molecular cell 2008;31(3):406-14.
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2008: Kontnik Renee; Bosak Tanja; Butcher Rebecca A; Brocks Jochen J; Losick Richard; Clardy Jon; Pearson Ann
Sporulenes, heptaprenyl metabolites from Bacillus subtilis spores.
Organic letters 2008;10(16):3551-4.
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2008: Camp Amy H; Losick Richard
A novel pathway of intercellular signalling in Bacillus subtilis involves a protein with similarity to a component of type III secretion channels.
Molecular microbiology 2008;69(2):402-17.
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2008: Earl Ashlee M; Losick Richard; Kolter Roberto
Ecology and genomics of Bacillus subtilis.
Trends in microbiology 2008;16(6):269-75.
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2008: Chu Frances; Kearns Daniel B; McLoon Anna; Chai Yunrong; Kolter Roberto; Losick Richard
A novel regulatory protein governing biofilm formation in Bacillus subtilis.
Molecular microbiology 2008;68(5):1117-27.
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2008: Bosak T; Losick R M; Pearson A
A polycyclic terpenoid that alleviates oxidative stress.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(18):6725-9.
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2008: Handler Aaron A; Lim Joo Eun; Losick Richard
Peptide inhibitor of cytokinesis during sporulation in Bacillus subtilis.
Molecular microbiology 2008;68(3):588-99.
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2008: Losick Richard; Desplan Claude
Stochasticity and cell fate.
Science (New York, N.Y.) 2008;320(5872):65-8.
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2008: Vlamakis Hera; Aguilar Claudio; Losick Richard; Kolter Roberto
Control of cell fate by the formation of an architecturally complex bacterial community.
Genes & development 2008;22(7):945-53.
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2008: Chai Yunrong; Chu Frances; Kolter Roberto; Losick Richard
Bistability and biofilm formation in Bacillus subtilis.
Molecular microbiology 2008;67(2):254-63.
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2007: Aguilar Claudio; Vlamakis Hera; Losick Richard; Kolter Roberto
Thinking about Bacillus subtilis as a multicellular organism.
Current opinion in microbiology 2007;10(6):638-43.
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2007: Ferguson Caitlin C; Camp Amy H; Losick Richard
gerT, a newly discovered germination gene under the control of the sporulation transcription factor sigmaK in Bacillus subtilis.
Journal of bacteriology 2007;189(21):7681-9.
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2007: Chastanet Arnaud; Losick Richard
Engulfment during sporulation in Bacillus subtilis is governed by a multi-protein complex containing tandemly acting autolysins.
Molecular microbiology 2007;64(1):139-52.
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2007: Earl Ashlee M; Losick Richard; Kolter Roberto
Bacillus subtilis genome diversity.
Journal of bacteriology 2007;189(3):1163-70.
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2006: Ramamurthi Kumaran S; Clapham Katie Rose; Losick Richard
Peptide anchoring spore coat assembly to the outer forespore membrane in Bacillus subtilis.
Molecular microbiology 2006;62(6):1547-57.
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2006: Dubnau David; Losick Richard
Bistability in bacteria.
Molecular microbiology 2006;61(3):564-72.
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2006: Ellermeier Craig D; Losick Richard
Evidence for a novel protease governing regulated intramembrane proteolysis and resistance to antimicrobial peptides in Bacillus subtilis.
Genes & development 2006;20(14):1911-22.
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2006: Bassler Bonnie L; Losick Richard
Bacterially speaking.
Cell 2006;125(2):237-46.
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2006: Wang Stephanie T; Setlow Barbara; Conlon Erin M; Lyon Jessica L; Imamura Daisuke; Sato Tsutomu; Setlow Peter; Losick Richard; Eichenberger Patrick
The forespore line of gene expression in Bacillus subtilis.
Journal of molecular biology 2006;358(1):16-37.
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2006: Ellermeier Craig D; Hobbs Errett C; Gonzalez-Pastor Jose E; Losick Richard
A three-protein signaling pathway governing immunity to a bacterial cannibalism toxin.
Cell 2006;124(3):549-59.
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2006: Branda Steven S; Chu Frances; Kearns Daniel B; Losick Richard; Kolter Roberto
A major protein component of the Bacillus subtilis biofilm matrix.
Molecular microbiology 2006;59(4):1229-38.
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2006: Chu Frances; Kearns Daniel B; Branda Steven S; Kolter Roberto; Losick Richard
Targets of the master regulator of biofilm formation in Bacillus subtilis.
Molecular microbiology 2006;59(4):1216-28.
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2006: Silvaggi Jessica M; Perkins John B; Losick Richard
Genes for small, noncoding RNAs under sporulation control in Bacillus subtilis.
Journal of bacteriology 2006;188(2):532-41.
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2005: Kearns Daniel B; Losick Richard
Cell population heterogeneity during growth of Bacillus subtilis.
Genes & development 2005;19(24):3083-94.
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2005: Silvaggi Jessica M; Perkins John B; Losick Richard
Small untranslated RNA antitoxin in Bacillus subtilis.
Journal of bacteriology 2005;187(19):6641-50.
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2005: Fujita Masaya; Losick Richard
Evidence that entry into sporulation in Bacillus subtilis is governed by a gradual increase in the level and activity of the master regulator Spo0A.
Genes & development 2005;19(18):2236-44.
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2005: Dworkin Jonathan; Losick Richard
Developmental commitment in a bacterium.
Cell 2005;121(3):401-9.
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2005: Carniol Karen; Ben-Yehuda Sigal; King Nicole; Losick Richard
Genetic dissection of the sporulation protein SpoIIE and its role in asymmetric division in Bacillus subtilis.
Journal of bacteriology 2005;187(10):3511-20.
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2005: Ben-Yehuda Sigal; Fujita Masya; Liu Xiaole Shirley; Gorbatyuk Boris; Skoko Dunja; Yan Jie; Marko John F; Liu Jun S; Eichenberger Patrick; Rudner David Z; Losick Richard
Defining a centromere-like element in Bacillus subtilis by Identifying the binding sites for the chromosome-anchoring protein RacA.
Molecular cell 2005;17(6):773-82.
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2005: Ramamurthi Kumaran S; Losick Richard M
Protein localization: reach out and touch the forespore.
Current biology : CB 2005;15(5):R165-7.
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2005: Fujita Masaya; González-Pastor José Eduardo; Losick Richard
High- and low-threshold genes in the Spo0A regulon of Bacillus subtilis.
Journal of bacteriology 2005;187(4):1357-68.
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2005: Kearns Daniel B; Chu Frances; Branda Steven S; Kolter Roberto; Losick Richard
A master regulator for biofilm formation by Bacillus subtilis.
Molecular microbiology 2005;55(3):739-49.
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2004: Silvaggi Jessica M; Popham David L; Driks Adam; Eichenberger Patrick; Losick Richard
Unmasking novel sporulation genes in Bacillus subtilis.
Journal of bacteriology 2004;186(23):8089-95.
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2004: Eichenberger Patrick; Fujita Masaya; Jensen Shane T; Conlon Erin M; Rudner David Z; Wang Stephanie T; Ferguson Caitlin; Haga Koki; Sato Tsutomu; Liu Jun S; Losick Richard
The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis.
PLoS biology 2004;2(10):e328.
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2004: van Ooij Christiaan; Eichenberger Patrick; Losick Richard
Dynamic patterns of subcellular protein localization during spore coat morphogenesis in Bacillus subtilis.
Journal of bacteriology 2004;186(14):4441-8.
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2004: Carniol Karen; Kim Tae-Jong; Price Chester W; Losick Richard
Insulation of the sigmaF regulatory system in Bacillus subtilis.
Journal of bacteriology 2004;186(13):4390-4.
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2004: Branda Steven S; González-Pastor José Eduardo; Dervyn Etienne; Ehrlich S Dusko; Losick Richard; Kolter Roberto
Genes involved in formation of structured multicellular communities by Bacillus subtilis.
Journal of bacteriology 2004;186(12):3970-9.
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2004: Gehring Amy M; Wang Stephanie T; Kearns Daniel B; Storer Narie Yoo; Losick Richard
Novel genes that influence development in Streptomyces coelicolor.
Journal of bacteriology 2004;186(11):3570-7.
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2004: Kearns Daniel B; Chu Frances; Rudner Rivka; Losick Richard
Genes governing swarming in Bacillus subtilis and evidence for a phase variation mechanism controlling surface motility.
Molecular microbiology 2004;52(2):357-69.
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2004: Carniol Karen; Eichenberger Patrick; Losick Richard
A threshold mechanism governing activation of the developmental regulatory protein sigma F in Bacillus subtilis.
The Journal of biological chemistry 2004;279(15):14860-70.
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2003: Ben-Yehuda Sigal; Rudner David Z; Losick Richard
Assembly of the SpoIIIE DNA translocase depends on chromosome trapping in Bacillus subtilis.
Current biology : CB 2003;13(24):2196-200.
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2003: Molle Virginie; Fujita Masaya; Jensen Shane T; Eichenberger Patrick; González-Pastor José E; Liu Jun S; Losick Richard
The Spo0A regulon of Bacillus subtilis.
Molecular microbiology 2003;50(5):1683-701.
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2003: Pan Qi; Losick Richard; Rudner David Z
A second PDZ-containing serine protease contributes to activation of the sporulation transcription factor sigmaK in Bacillus subtilis.
Journal of bacteriology 2003;185(20):6051-6.
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2003: Pan Qi; Losick Richard
Unique degradation signal for ClpCP in Bacillus subtilis.
Journal of bacteriology 2003;185(17):5275-8.
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2003: Kearns Daniel B; Losick Richard
Swarming motility in undomesticated Bacillus subtilis.
Molecular microbiology 2003;49(3):581-90.
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2003: González-Pastor José E; Hobbs Errett C; Losick Richard
Cannibalism by sporulating bacteria.
Science (New York, N.Y.) 2003;301(5632):510-3.
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2003: Ho Margaret S; Carniol Karen; Losick Richard
Evidence in support of a docking model for the release of the transcription factor sigma F from the antisigma factor SpoIIAB in Bacillus subtilis.
The Journal of biological chemistry 2003;278(23):20898-905.
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2003: Fujita Masaya; Losick Richard
The master regulator for entry into sporulation in Bacillus subtilis becomes a cell-specific transcription factor after asymmetric division.
Genes & development 2003;17(9):1166-74.
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2003: Eichenberger Patrick; Jensen Shane T; Conlon Erin M; van Ooij Christiaan; Silvaggi Jessica; González-Pastor José Eduardo; Fujita Masaya; Ben-Yehuda Sigal; Stragier Patrick; Liu Jun S; Losick Richard
The sigmaE regulon and the identification of additional sporulation genes in Bacillus subtilis.
Journal of molecular biology 2003;327(5):945-72.
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2003: Molle Virginie; Nakaura Yoshiko; Shivers Robert P; Yamaguchi Hirotake; Losick Richard; Fujita Yasutaro; Sonenshein Abraham L
Additional targets of the Bacillus subtilis global regulator CodY identified by chromatin immunoprecipitation and genome-wide transcript analysis.
Journal of bacteriology 2003;185(6):1911-22.
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2003: van Ooij Christiaan; Losick Richard
Subcellular localization of a small sporulation protein in Bacillus subtilis.
Journal of bacteriology 2003;185(4):1391-8.
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2003: Ben-Yehuda Sigal; Rudner David Z; Losick Richard
RacA, a bacterial protein that anchors chromosomes to the cell poles.
Science (New York, N.Y.) 2003;299(5606):532-6.
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2002: Shapiro Lucy; McAdams Harley H; Losick Richard
Generating and exploiting polarity in bacteria.
Science (New York, N.Y.) 2002;298(5600):1942-6.
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2002: Dworkin Jonathan; Losick Richard
Does RNA polymerase help drive chromosome segregation in bacteria?
Proceedings of the National Academy of Sciences of the United States of America 2002;99(22):14089-94.
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2002: Gueiros-Filho Frederico J; Losick Richard
A widely conserved bacterial cell division protein that promotes assembly of the tubulin-like protein FtsZ.
Genes & development 2002;16(19):2544-56.
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2002: Britton Robert A; Eichenberger Patrick; Gonzalez-Pastor Jose Eduardo; Fawcett Paul; Monson Rita; Losick Richard; Grossman Alan D
Genome-wide analysis of the stationary-phase sigma factor (sigma-H) regulon of Bacillus subtilis.
Journal of bacteriology 2002;184(17):4881-90.
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2002: Kemp Jennifer T; Driks Adam; Losick Richard
FtsA mutants of Bacillus subtilis impaired in sporulation.
Journal of bacteriology 2002;184(14):3856-63.
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2002: Rudner David Z; Pan Qi; Losick Richard M
Evidence that subcellular localization of a bacterial membrane protein is achieved by diffusion and capture.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(13):8701-6.
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2002: Nohturfft Axel; Losick Richard
Cell biology. Fats, flies, and palmitate.
Science (New York, N.Y.) 2002;296(5569):857-8.
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2002: Ben-Yehuda Sigal; Losick Richard
Asymmetric cell division in B. subtilis involves a spiral-like intermediate of the cytokinetic protein FtsZ.
Cell 2002;109(2):257-66.
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2002: Rudner David Z; Losick Richard
A sporulation membrane protein tethers the pro-sigmaK processing enzyme to its inhibitor and dictates its subcellular localization.
Genes & development 2002;16(8):1007-18.
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2002: Fujita Masaya; Losick Richard
An investigation into the compartmentalization of the sporulation transcription factor sigmaE in Bacillus subtilis.
Molecular microbiology 2002;43(1):27-38.
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2001: Eichenberger P; Fawcett P; Losick R
A three-protein inhibitor of polar septation during sporulation in Bacillus subtilis.
Molecular microbiology 2001;42(5):1147-62.
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2001: Rudner D Z; Losick R
Morphological coupling in development: lessons from prokaryotes.
Developmental cell 2001;1(6):733-42.
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2001: Dworkin J; Losick R
Differential gene expression governed by chromosomal spatial asymmetry.
Cell 2001;107(3):339-46.
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2001: Pan Q; Garsin D A; Losick R
Self-reinforcing activation of a cell-specific transcription factor by proteolysis of an anti-sigma factor in B. subtilis.
Molecular cell 2001;8(4):873-83.
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2001: Gehring A M; Yoo N J; Losick R
RNA polymerase sigma factor that blocks morphological differentiation by Streptomyces coelicolor.
Journal of bacteriology 2001;183(20):5991-6.
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2001: Branda S S; González-Pastor J E; Ben-Yehuda S; Losick R; Kolter R
Fruiting body formation by Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11621-6.
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2001: Losick R; Sonenshein A L
Molecular biology. Turning gene regulation on its head.
Science (New York, N.Y.) 2001;293(5537):2018-9.
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2001: Yang M C; Losick R
Cytological evidence for association of the ends of the linear chromosome in Streptomyces coelicolor.
Journal of bacteriology 2001;183(17):5180-6.
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2001: Graumann P L; Losick R
Coupling of asymmetric division to polar placement of replication origin regions in Bacillus subtilis.
Journal of bacteriology 2001;183(13):4052-60.
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2001: Dworkin J; Losick R
Linking nutritional status to gene activation and development.
Genes & development 2001;15(9):1051-4.
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2000: Gehring A M; Nodwell J R; Beverley S M; Losick R
Genomewide insertional mutagenesis in Streptomyces coelicolor reveals additional genes involved in morphological differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(17):9642-7.
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2000: Fawcett P; Eichenberger P; Losick R; Youngman P
The transcriptional profile of early to middle sporulation in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(14):8063-8.
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2000: Shapiro L; Losick R
Dynamic spatial regulation in the bacterial cell.
Cell 2000;100(1):89-98.
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1999: Rudner D Z; Fawcett P; Losick R
A family of membrane-embedded metalloproteases involved in regulated proteolysis of membrane-associated transcription factors.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):14765-70.
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1999: Losick R; Shapiro L
Changing views on the nature of the bacterial cell: from biochemistry to cytology.
Journal of bacteriology 1999;181(14):4143-5.
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1999: King N; Dreesen O; Stragier P; Pogliano K; Losick R
Septation, dephosphorylation, and the activation of sigmaF during sporulation in Bacillus subtilis.
Genes & development 1999;13(9):1156-67.
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1999: Losick R; Dworkin J
Linking asymmetric division to cell fate: teaching an old microbe new tricks.
Genes & development 1999;13(4):377-81.
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1999: Nodwell J R; Yang M; Kuo D; Losick R
Extracellular complementation and the identification of additional genes involved in aerial mycelium formation in Streptomyces coelicolor.
Genetics 1999;151(2):569-84.
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1999: Price K D; Losick R
A four-dimensional view of assembly of a morphogenetic protein during sporulation in Bacillus subtilis.
Journal of bacteriology 1999;181(3):781-90.
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1998: Garsin D A; Duncan L; Paskowitz D M; Losick R
The kinase activity of the antisigma factor SpoIIAB is required for activation as well as inhibition of transcription factor sigmaF during sporulation in Bacillus subtilis.
Journal of molecular biology 1998;284(3):569-78.
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1998: Garsin D A; Paskowitz D M; Duncan L; Losick R
Evidence for common sites of contact between the antisigma factor SpoIIAB and its partners SpoIIAA and the developmental transcription factor sigmaF in Bacillus subtilis.
Journal of molecular biology 1998;284(3):557-68.
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1998: Losick R; Shapiro L
DNA replication. Bringing the mountain to Mohammed.
Science (New York, N.Y.) 1998;282(5393):1430-1.
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1998: Teleman A A; Graumann P L; Lin D C; Grossman A D; Losick R
Chromosome arrangement within a bacterium.
Current biology : CB 1998;8(20):1102-9.
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1998: Angert E R; Losick R M
Propagation by sporulation in the guinea pig symbiont Metabacterium polyspora.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(17):10218-23.
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1998: Pogliano J; Dong J M; De Wulf P; Furlong D; Boyd D; Losick R; Pogliano K; Lin E C
Aberrant cell division and random FtsZ ring positioning in Escherichia coli cpxA* mutants.
Journal of bacteriology 1998;180(13):3486-90.
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1998: Webb C D; Graumann P L; Kahana J A; Teleman A A; Silver P A; Losick R
Use of time-lapse microscopy to visualize rapid movement of the replication origin region of the chromosome during the cell cycle in Bacillus subtilis.
Molecular microbiology 1998;28(5):883-92.
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1998: Kolter R; Losick R
One for all and all for one.
Science (New York, N.Y.) 1998;280(5361):226-7.
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1998: Resnekov O; Losick R
Negative regulation of the proteolytic activation of a developmental transcription factor in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):3162-7.
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1998: Nodwell J R; Losick R
Purification of an extracellular signaling molecule involved in production of aerial mycelium by Streptomyces coelicolor.
Journal of bacteriology 1998;180(5):1334-7.
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1998: Losick R
Summary: three decades after sigma.
Cold Spring Harbor symposia on quantitative biology 1998;63():653-66.
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1997: Schwedock J; McCormick J R; Angert E R; Nodwell J R; Losick R
Assembly of the cell division protein FtsZ into ladder-like structures in the aerial hyphae of Streptomyces coelicolor.
Molecular microbiology 1997;25(5):847-58.
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1997: Levin P A; Losick R; Stragier P; Arigoni F
Localization of the sporulation protein SpoIIE in Bacillus subtilis is dependent upon the cell division protein FtsZ.
Molecular microbiology 1997;25(5):839-46.
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1997: Gordon G S; Sitnikov D; Webb C D; Teleman A; Straight A; Losick R; Murray A W; Wright A
Chromosome and low copy plasmid segregation in E. coli: visual evidence for distinct mechanisms.
Cell 1997;90(6):1113-21.
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1997: Weiss D S; Pogliano K; Carson M; Guzman L M; Fraipont C; Nguyen-Distèche M; Losick R; Beckwith J
Localization of the Escherichia coli cell division protein Ftsl (PBP3) to the division site and cell pole.
Molecular microbiology 1997;25(4):671-81.
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1997: Price K D; Roels S; Losick R
A Bacillus subtilis gene encoding a protein similar to nucleotide sugar transferases influences cell shape and viability.
Journal of bacteriology 1997;179(15):4959-61.
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1997: Pogliano K; Hofmeister A E; Losick R
Disappearance of the sigma E transcription factor from the forespore and the SpoIIE phosphatase from the mother cell contributes to establishment of cell-specific gene expression during sporulation in Bacillus subtilis.
Journal of bacteriology 1997;179(10):3331-41.
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1997: Shapiro L; Losick R
Protein localization and cell fate in bacteria.
Science (New York, N.Y.) 1997;276(5313):712-8.
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1997: Webb C D; Teleman A; Gordon S; Straight A; Belmont A; Lin D C; Grossman A D; Wright A; Losick R
Bipolar localization of the replication origin regions of chromosomes in vegetative and sporulating cells of B. subtilis.
Cell 1997;88(5):667-74.
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1997: Decatur A; McMurry M T; Kunkel B N; Losick R
Translation of the mRNA for the sporulation gene spoIIID of Bacillus subtilis is dependent upon translation of a small upstream open reading frame.
Journal of bacteriology 1997;179(4):1324-8.
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1997: Pogliano J; Pogliano K; Weiss D S; Losick R; Beckwith J
Inactivation of FtsI inhibits constriction of the FtsZ cytokinetic ring and delays the assembly of FtsZ rings at potential division sites.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(2):559-64.
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1997: Hofmeister A; Losick R
Establishment of cell type in a primitive organism by cell-specific elimination and proteolytic activation of a transcription factor.
Cold Spring Harbor symposia on quantitative biology 1997;62():49-55.
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1996: Nodwell J R; McGovern K; Losick R
An oligopeptide permease responsible for the import of an extracellular signal governing aerial mycelium formation in Streptomyces coelicolor.
Molecular microbiology 1996;22(5):881-93.
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1996: Decatur A L; Losick R
Three sites of contact between the Bacillus subtilis transcription factor sigmaF and its antisigma factor SpoIIAB.
Genes & development 1996;10(18):2348-58.
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1996: McCormick J R; Losick R
Cell division gene ftsQ is required for efficient sporulation but not growth and viability in Streptomyces coelicolor A3(2).
Journal of bacteriology 1996;178(17):5295-301.
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1996: Decatur A; Losick R
Identification of additional genes under the control of the transcription factor sigma F of Bacillus subtilis.
Journal of bacteriology 1996;178(16):5039-41.
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1996: Alper S; Dufour A; Garsin D A; Duncan L; Losick R
Role of adenosine nucleotides in the regulation of a stress-response transcription factor in Bacillus subtilis.
Journal of molecular biology 1996;260(2):165-77.
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1996: Duncan L; Alper S; Losick R
SpoIIAA governs the release of the cell-type specific transcription factor sigma F from its anti-sigma factor SpoIIAB.
Journal of molecular biology 1996;260(2):147-64.
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1996: Resnekov O; Alper S; Losick R
Subcellular localization of proteins governing the proteolytic activation of a developmental transcription factor in Bacillus subtilis.
Genes to cells : devoted to molecular & cellular mechanisms 1996;1(6):529-42.
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1996: Arigoni F; Duncan L; Alper S; Losick R; Stragier P
SpoIIE governs the phosphorylation state of a protein regulating transcription factor sigma F during sporulation in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(8):3238-42.
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1996: Levin P A; Losick R
Transcription factor Spo0A switches the localization of the cell division protein FtsZ from a medial to a bipolar pattern in Bacillus subtilis.
Genes & development 1996;10(4):478-88.
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1996: Stragier P; Losick R
Molecular genetics of sporulation in Bacillus subtilis.
Annual review of genetics 1996;30():297-41.
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1995: Pogliano K; Harry E; Losick R
Visualization of the subcellular location of sporulation proteins in Bacillus subtilis using immunofluorescence microscopy.
Molecular microbiology 1995;18(3):459-70.
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1995: Roels S; Losick R
Adjacent and divergently oriented operons under the control of the sporulation regulatory protein GerE in Bacillus subtilis.
Journal of bacteriology 1995;177(21):6263-75.
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1995: Webb C D; Decatur A; Teleman A; Losick R
Use of green fluorescent protein for visualization of cell-specific gene expression and subcellular protein localization during sporulation in Bacillus subtilis.
Journal of bacteriology 1995;177(20):5906-11.
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1995: Hofmeister A E; Londoño-Vallejo A; Harry E; Stragier P; Losick R
Extracellular signal protein triggering the proteolytic activation of a developmental transcription factor in B. subtilis.
Cell 1995;83(2):219-26.
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1995: Duncan L; Alper S; Arigoni F; Losick R; Stragier P
Activation of cell-specific transcription by a serine phosphatase at the site of asymmetric division.
Science (New York, N.Y.) 1995;270(5236):641-4.
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1995: Arigoni F; Pogliano K; Webb C D; Stragier P; Losick R
Localization of protein implicated in establishment of cell type to sites of asymmetric division.
Science (New York, N.Y.) 1995;270(5236):637-40.
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1995: Resnekov O; Driks A; Losick R
Identification and characterization of sporulation gene spoVS from Bacillus subtilis.
Journal of bacteriology 1995;177(19):5628-35.
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1995: Harry E J; Pogliano K; Losick R
Use of immunofluorescence to visualize cell-specific gene expression during sporulation in Bacillus subtilis.
Journal of bacteriology 1995;177(12):3386-93.
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1995: Sacco M; Ricca E; Losick R; Cutting S
An additional GerE-controlled gene encoding an abundant spore coat protein from Bacillus subtilis.
Journal of bacteriology 1995;177(2):372-7.
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1994: Duncan L; Alper S; Losick R
Establishment of cell type specific gene transcription during sporulation in Bacillus subtilis.
Current opinion in genetics & development 1994;4(5):630-6.
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1994: McCormick J R; Su E P; Driks A; Losick R
Growth and viability of Streptomyces coelicolor mutant for the cell division gene ftsZ.
Molecular microbiology 1994;14(2):243-54.
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1994: Alper S; Duncan L; Losick R
An adenosine nucleotide switch controlling the activity of a cell type-specific transcription factor in B. subtilis.
Cell 1994;77(2):195-205.
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1994: Levin P A; Losick R
Characterization of a cell division gene from Bacillus subtilis that is required for vegetative and sporulation septum formation.
Journal of bacteriology 1994;176(5):1451-9.
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1994: Driks A; Roels S; Beall B; Moran C P; Losick R
Subcellular localization of proteins involved in the assembly of the spore coat of Bacillus subtilis.
Genes & development 1994;8(2):234-44.
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1994: Losick R
RNA polymerase sigma factors and cell-specific gene transcription in a simple developing organism.
Harvey lectures 1994;90():1-17.
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1993: Losick R; Shapiro L
Checkpoints that couple gene expression to morphogenesis.
Science (New York, N.Y.) 1993;262(5137):1227-8.
-
1993: Oke V; Losick R
Multilevel regulation of the sporulation transcription factor sigma K in Bacillus subtilis.
Journal of bacteriology 1993;175(22):7341-7.
-
1993: Levin P A; Fan N; Ricca E; Driks A; Losick R; Cutting S
An unusually small gene required for sporulation by Bacillus subtilis.
Molecular microbiology 1993;9(4):761-71.
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1993: Willey J; Schwedock J; Losick R
Multiple extracellular signals govern the production of a morphogenetic protein involved in aerial mycelium formation by Streptomyces coelicolor.
Genes & development 1993;7(5):895-903.
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1993: Duncan L; Losick R
SpoIIAB is an anti-sigma factor that binds to and inhibits transcription by regulatory protein sigma F from Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(6):2325-9.
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1993: Beall B; Driks A; Losick R; Moran C P
Cloning and characterization of a gene required for assembly of the Bacillus subtilis spore coat.
Journal of bacteriology 1993;175(6):1705-16.
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1993: Margolis P S; Driks A; Losick R
Sporulation gene spoIIB from Bacillus subtilis.
Journal of bacteriology 1993;175(2):528-40.
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1992: Levin P A; Margolis P S; Setlow P; Losick R; Sun D
Identification of Bacillus subtilis genes for septum placement and shape determination.
Journal of bacteriology 1992;174(21):6717-28.
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1992: Zheng L; Halberg R; Roels S; Ichikawa H; Kroos L; Losick R
Sporulation regulatory protein GerE from Bacillus subtilis binds to and can activate or repress transcription from promoters for mother-cell-specific genes.
Journal of molecular biology 1992;226(4):1037-50.
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1992: Geistlich M; Losick R; Turner J R; Rao R N
Characterization of a novel regulatory gene governing the expression of a polyketide synthase gene in Streptomyces ambofaciens.
Molecular microbiology 1992;6(14):2019-29.
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1992: Ricca E; Cutting S; Losick R
Characterization of bofA, a gene involved in intercompartmental regulation of pro-sigma K processing during sporulation in Bacillus subtilis.
Journal of bacteriology 1992;174(10):3177-84.
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1992: Fan N; Cutting S; Losick R
Characterization of the Bacillus subtilis sporulation gene spoVK.
Journal of bacteriology 1992;174(3):1053-4.
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1992: Losick R; Stragier P
Crisscross regulation of cell-type-specific gene expression during development in B. subtilis.
Nature 1992;355(6361):601-4.
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1992: Roels S; Driks A; Losick R
Characterization of spoIVA, a sporulation gene involved in coat morphogenesis in Bacillus subtilis.
Journal of bacteriology 1992;174(2):575-85.
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1991: Driks A; Losick R
Compartmentalized expression of a gene under the control of sporulation transcription factor sigma E in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(22):9934-8.
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1991: Margolis P; Driks A; Losick R
Establishment of cell type by compartmentalized activation of a transcription factor.
Science (New York, N.Y.) 1991;254(5031):562-5.
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1991: Cutting S; Roels S; Losick R
Sporulation operon spoIVF and the characterization of mutations that uncouple mother-cell from forespore gene expression in Bacillus subtilis.
Journal of molecular biology 1991;221(4):1237-56.
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1991: Margolis P; Driks A; Losick R
Differentiation and the establishment of cell type during sporulation in Bacillus subtilis.
Current opinion in genetics & development 1991;1(3):330-5.
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1991: Willey J; Santamaria R; Guijarro J; Geistlich M; Losick R
Extracellular complementation of a developmental mutation implicates a small sporulation protein in aerial mycelium formation by S. coelicolor.
Cell 1991;65(4):641-50.
-
1991: Cutting S; Zheng L B; Losick R
Gene encoding two alkali-soluble components of the spore coat from Bacillus subtilis.
Journal of bacteriology 1991;173(9):2915-9.
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1991: Cutting S; Driks A; Schmidt R; Kunkel B; Losick R
Forespore-specific transcription of a gene in the signal transduction pathway that governs Pro-sigma K processing in Bacillus subtilis.
Genes & development 1991;5(3):456-66.
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1991: Healy J; Weir J; Smith I; Losick R
Post-transcriptional control of a sporulation regulatory gene encoding transcription factor sigma H in Bacillus subtilis.
Molecular microbiology 1991;5(2):477-87.
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1990: Schmidt R; Margolis P; Duncan L; Coppolecchia R; Moran C P; Losick R
Control of developmental transcription factor sigma F by sporulation regulatory proteins SpoIIAA and SpoIIAB in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(23):9221-5.
-
1990: Stragier P; Losick R
Cascades of sigma factors revisited.
Molecular microbiology 1990;4(11):1801-6.
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1990: Daniels D; Zuber P; Losick R
Two amino acids in an RNA polymerase sigma factor involved in the recognition of adjacent base pairs in the -10 region of a cognate promoter.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(20):8075-9.
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1990: Cutting S; Oke V; Driks A; Losick R; Lu S; Kroos L
A forespore checkpoint for mother cell gene expression during development in B. subtilis.
Cell 1990;62(2):239-50.
-
1990: Kunkel B; Losick R; Stragier P
The Bacillus subtilis gene for the development transcription factor sigma K is generated by excision of a dispensable DNA element containing a sporulation recombinase gene.
Genes & development 1990;4(4):525-35.
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1990: Zheng L B; Losick R
Cascade regulation of spore coat gene expression in Bacillus subtilis.
Journal of molecular biology 1990;212(4):645-60.
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1989: Kunkel B; Kroos L; Poth H; Youngman P; Losick R
Temporal and spatial control of the mother-cell regulatory gene spoIIID of Bacillus subtilis.
Genes & development 1989;3(11):1735-44.
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1989: Jaacks K J; Healy J; Losick R; Grossman A D
Identification and characterization of genes controlled by the sporulation-regulatory gene spo0H in Bacillus subtilis.
Journal of bacteriology 1989;171(8):4121-9.
-
1989: Cutting S; Panzer S; Losick R
Regulatory studies on the promoter for a gene governing synthesis and assembly of the spore coat in Bacillus subtilis.
Journal of molecular biology 1989;207(2):393-404.
-
1989: Zuber P; Healy J; Carter H L; Cutting S; Moran C P; Losick R
Mutation changing the specificity of an RNA polymerase sigma factor.
Journal of molecular biology 1989;206(4):605-14.
-
1989: Weber J M; Schoner B; Losick R
Identification of a gene required for the terminal step in erythromycin A biosynthesis in Saccharopolyspora erythraea (Streptomyces erythreus).
Gene 1989;75(2):235-41.
-
1989: Stragier P; Kunkel B; Kroos L; Losick R
Chromosomal rearrangement generating a composite gene for a developmental transcription factor.
Science (New York, N.Y.) 1989;243(4890):507-12.
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1989: Panzer S; Losick R; Sun D; Setlow P
Evidence for an additional temporal class of gene expression in the forespore compartment of sporulating Bacillus subtilis.
Journal of bacteriology 1989;171(1):561-4.
-
1989: Kroos L; Kunkel B; Losick R
Switch protein alters specificity of RNA polymerase containing a compartment-specific sigma factor.
Science (New York, N.Y.) 1989;243(4890):526-9.
-
1988: Weber J M; Losick R
The use of a chromosome integration vector to map erythromycin resistance and production genes in Saccharopolyspora erythraea (Streptomyces erythraeus).
Gene 1988;68(2):173-80.
-
1988: Zheng L B; Donovan W P; Fitz-James P C; Losick R
Gene encoding a morphogenic protein required in the assembly of the outer coat of the Bacillus subtilis endospore.
Genes & development 1988;2(8):1047-54.
-
1988: Kunkel B; Sandman K; Panzer S; Youngman P; Losick R
The promoter for a sporulation gene in the spoIVC locus of Bacillus subtilis and its use in studies of temporal and spatial control of gene expression.
Journal of bacteriology 1988;170(8):3513-22.
-
1988: Lampe M; Binnie C; Schmidt R; Losick R
Cloned gene encoding the delta subunit of Bacillus subtilis RNA polymerase.
Gene 1988;67(1):13-9.
-
1988: Grossman A D; Losick R
Extracellular control of spore formation in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(12):4369-73.
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1988: Schauer A; Ranes M; Santamaria R; Guijarro J; Lawlor E; Mendez C; Chater K; Losick R
Visualizing gene expression in time and space in the filamentous bacterium Streptomyces coelicolor.
Science (New York, N.Y.) 1988;240(4853):768-72.
-
1988: Sandman K; Kroos L; Cutting S; Youngman P; Losick R
Identification of the promoter for a spore coat protein gene in Bacillus subtilis and studies on the regulation of its induction at a late stage of sporulation.
Journal of molecular biology 1988;200(3):461-73.
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1988: Guijarro J; Santamaria R; Schauer A; Losick R
Promoter determining the timing and spatial localization of transcription of a cloned Streptomyces coelicolor gene encoding a spore-associated polypeptide.
Journal of bacteriology 1988;170(4):1895-901.
-
1988: Ray C; Igo M; Shafer W; Losick R; Moran C P
Suppression of ctc promoter mutations in Bacillus subtilis.
Journal of bacteriology 1988;170(2):900-7.
-
1987: Sandman K; Losick R; Youngman P
Genetic analysis of Bacillus subtilis spo mutations generated by Tn917-mediated insertional mutagenesis.
Genetics 1987;117(4):603-17.
-
1987: Donovan W; Zheng L B; Sandman K; Losick R
Genes encoding spore coat polypeptides from Bacillus subtilis.
Journal of molecular biology 1987;196(1):1-10.
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