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Yu Chen Barrett

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Eugen Koren; Holly W Smith; Elizabeth Shores; Gopi Shankar; Deborah Finco-Kent; Bonita Rup; Yu Chen Barrett; Viswanath Devanarayan; boris gorovits; Shalini Gupta; Thomas Parish; Valerie Quarmby; Michael Moxness; Steven J Swanson; Gary Taniguchi; Linda A Zuckerman; Christopher C Stebbins; Anthony Mire-Sluis
Recommendations on risk-based strategies for detection and characterization of antibodies against biotechnology products.
Yu Chen Barrett; William Ebling; Henry J Pieniaszek; Jeffrey T Billheimer; Dietmar Seiffert
Validation and implementation of drug-dependent antibody assays in clinical trials for safety monitoring of patients dosed with roxifiban, an orally bioavailable glycoprotein IIb/IIIa antagonist.
Jean W Lee; Viswanath Devanarayan; Yu Chen Barrett; Russell Weiner; John Allinson; Scott Fountain; Stephen Keller; Ira Weinryb; Marie Green; Larry Duan; James A Rogers; Robert Millham; Peter J O'Brien; Jeffrey Sailstad; Masood N Khan; Chad Ray; John A Wagner
Fit-for-purpose method development and validation for successful biomarker measurement.

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All Publications

2008: Eugen Koren; Holly W Smith; Elizabeth Shores; Gopi Shankar; Deborah Finco-Kent; Bonita Rup; Yu Chen Barrett; Viswanath Devanarayan; boris gorovits; Shalini Gupta; Thomas Parish; Valerie Quarmby; Michael Moxness; Steven J Swanson; Gary Taniguchi; Linda A Zuckerman; Christopher C Stebbins; Anthony Mire-Sluis
Recommendations on risk-based strategies for detection and characterization of antibodies against biotechnology products.
Journal of immunological methods 2008;333(1-2):1-9.
2007: Yu Chen Barrett; William Ebling; Henry J Pieniaszek; Jeffrey T Billheimer; Dietmar Seiffert
Validation and implementation of drug-dependent antibody assays in clinical trials for safety monitoring of patients dosed with roxifiban, an orally bioavailable glycoprotein IIb/IIIa antagonist.
Journal of pharmaceutical and biomedical analysis 2007;44(4):938-46.
2006: Jean W Lee; Viswanath Devanarayan; Yu Chen Barrett; Russell Weiner; John Allinson; Scott Fountain; Stephen Keller; Ira Weinryb; Marie Green; Larry Duan; James A Rogers; Robert Millham; Peter J O'Brien; Jeffrey Sailstad; Masood N Khan; Chad Ray; John A Wagner
Fit-for-purpose method development and validation for successful biomarker measurement.
Pharmaceutical research 2006;23(2):312-28.
2005: Yu Chen Barrett; Billy Akinsanya; Shu-Ying Chang; Ole Vesterqvist
Automated on-line SPE LC-MS/MS method to quantitate 6beta-hydroxycortisol and cortisol in human urine: use of the 6beta-hydroxycortisol to cortisol ratio as an indicator of CYP3A4 activity.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;821(2):159-65.
2004: Anthony Mire-Sluis; Yu Chen Barrett; Viswanath Devanarayan; Eugene Koren; Hank Liu; Mauricio Maia; Thomas Parish; George Scott; Gopi Shankar; Elizabeth Shores; Steven J Swanson; Gary Taniguchi; Daniel Wierda; Linda A Zuckerman
Recommendations for the design and optimization of immunoassays used in the detection of host antibodies against biotechnology products.
Journal of immunological methods 2004;289(1-2):1-16.
2003: Henry J Pieniaszek; Anna F Davidson; Harry L Walton; Donald J P Pinto; Richard E Olson; Thomas M Reilly; Yu Chen Barrett
A double antibody radioimmunoassay for the determination of XV459, the active hydrolysis metabolite of roxifiban, in human plasma.
Journal of pharmaceutical and biomedical analysis 2003;30(5):1441-9.
2003: Dietmar Seiffert; Andrew M Stern; William Ebling; Richard J Rossi; Yu Chen Barrett; Richard Wynn; Gregory F Hollis; Bokang He; Cathy J Kieras; Donna L Pedicord; Debra Cromley; Tsushung Hua; Robert B Stein; Robert N Daly; Anthony Sferruzza; Henry J Pieniaszek; Jeffrey T Billheimer
Prospective testing for drug-dependent antibodies reduces the incidence of thrombocytopenia observed with the small molecule glycoprotein IIb/IIIa antagonist roxifiban: implications for the etiology of thrombocytopenia.
Blood 2003;101(1):58-63.