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Anu Loukola

Research Profile

Chemicals & Drugs

Physiology

Geographic Areas

Finland

Genes & Molecular Sequences

Procedures

DNA Mutational Analysis

Disorders

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Publications

TOP 3
Jacquelyn L Meyers; Emma Nyman; Richard J Rose; Jaakko Kaprio; Anu Loukola; Danielle M Dick
The association between DRD2/ANKK1 and genetically informed measures of alcohol use and problems.
Emma S Nyman; Susan L Smalley; Anja Taanila; Teppo Varilo; Tuula Hurtig; Marjo-Riitta Järvelin; Sandra Loo; Anu Loukola; James J McGough; Irma Moilanen; Stanley F Nelson; Leena Peltonen
Sex-specific influence of DRD2 on ADHD-type temperament in a large population-based birth cohort.
Ulla Broms; Anja Häppölä; Kauko Heikkilä; Katri H Heikkilä; Jaakko Kaprio; Kaisu Keskitalo-Vuokko; Tellervo Korhonen; Marine R Largeau; Pamela A F Madden; Tiina Paunio; Michele L Pergadia; Janne Pitkaniemi; Samuli Ripatti; O Salminen; Antti-Pekka Sarin; Juho Wedenoja; Anu Loukola
Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits.

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All Publications

2013: Jacquelyn L Meyers; Emma Nyman; Richard J Rose; Jaakko Kaprio; Anu Loukola; Danielle M Dick
The association between DRD2/ANKK1 and genetically informed measures of alcohol use and problems.
Addiction biology 2013;18(3):523-36.
2012: Emma S Nyman; Susan L Smalley; Anja Taanila; Teppo Varilo; Tuula Hurtig; Marjo-Riitta Järvelin; Sandra Loo; Anu Loukola; James J McGough; Irma Moilanen; Stanley F Nelson; Leena Peltonen
Sex-specific influence of DRD2 on ADHD-type temperament in a large population-based birth cohort.
Psychiatric genetics 2012;22(4):197-201.
2012: Ulla Broms; Anja Häppölä; Kauko Heikkilä; Katri H Heikkilä; Jaakko Kaprio; Kaisu Keskitalo-Vuokko; Tellervo Korhonen; Marine R Largeau; Pamela A F Madden; Tiina Paunio; Michele L Pergadia; Janne Pitkaniemi; Samuli Ripatti; O Salminen; Antti-Pekka Sarin; Juho Wedenoja; Anu Loukola
Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2012;14(6):720-33.
2012: Kaisu Keskitalo-Vuokko; Anu Loukola; Pamela A F Madden; Michele L Pergadia; Scott F Saccone; Ulla Broms; Jenni Hällfors; Jaakko Kaprio
Chromosome 20 shows linkage with DSM-IV nicotine dependence in Finnish adult smokers.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2012;14(2):153-60.
2011: Siddheshwar Utge; Erkki Kronholm; Anu Loukola; Hanna M Ollila; Timo Partonen; Markus Perola; Tarja Porkka-Heiskanen; Veikko Salomaa; Pia Soronen; Tiina Paunio
Shared genetic background for regulation of mood and sleep: association of GRIA3 with sleep duration in healthy Finnish women.
Sleep 2011;34(10):1309-16.
2011: Kaisu Keskitalo-Vuokko; Anu Loukola; Markus Perola; Janne Pitkaniemi; Samuli Ripatti; O Salminen; Veikko Salomaa; Arpo Aromaa; Ulla Broms; Markku Heliövaara; Jaakko Kaprio
Associations of nicotine intake measures with CHRN genes in Finnish smokers.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2011;13(8):686-90.
2011: Emma S Nyman; Nelson Freimer; Marjo-Riitta Järvelin; Matti Joukamaa; Virpi Leppä; Anu Loukola; Pirjo Mäki; Jouko Miettunen; Leena Peltonen; Pia Soronen; Sonja Sulkava; Juha Veijola; Tiina Paunio
Interaction of early environment, gender and genes of monoamine neurotransmission in the aetiology of depression in a large population-based Finnish birth cohort.
BMJ open 2011;1(1):e000087.
2010: Juho Wedenoja; Annamari Tuulio-Henriksson; Jaana Suvisaari; Anu Loukola; Tiina Paunio; Timo Partonen; Teppo Varilo; Jouko Lönnqvist; Leena Peltonen
Replication of association between working memory and Reelin, a potential modifier gene in schizophrenia.
Biological psychiatry 2010;67(10):983-91.
2010: Siddheshwar Utge; Pia Soronen; Timo Partonen; Anu Loukola; Erkki Kronholm; sami pirkola; Emma Nyman; Tarja Porkka-Heiskanen; Tiina Paunio
A population-based association study of candidate genes for depression and sleep disturbance.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(2):468-76.
2010: Siddheshwar J Utge; Pia Soronen; Anu Loukola; Erkki Kronholm; Hanna M Ollila; sami pirkola; Tarja Porkka-Heiskanen; Timo Partonen; Tiina Paunio
Systematic analysis of circadian genes in a population-based sample reveals association of TIMELESS with depression and sleep disturbance.
PloS one 2010;5(2):e9259.
2009: Michele L Pergadia; Arpana Agrawal; Anu Loukola; Grant W Montgomery; Ulla Broms; Scott F Saccone; Jen C Wang; Alexandre A Todorov; Kauko Heikkilä; Dixie J Statham; Anjali K Henders; Megan J Campbell; John P Rice; Richard D Todd; Andrew C Heath; Alison Goate; Leena Peltonen; Jaakko Kaprio; Nicholas G Martin; Pamela A F Madden
Genetic linkage findings for DSM-IV nicotine withdrawal in two populations.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(7):950-9.
2009: Emma S Nyman; Anu Loukola; Teppo Varilo; Jesper Ekelund; Juha Veijola; Matti Joukamaa; Anja Taanila; Anneli Pouta; Jouko Miettunen; Nelson Freimer; Marjo-Riitta Järvelin; Leena Peltonen
Impact of the dopamine receptor gene family on temperament traits in a population-based birth cohort.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(6):854-65.
2009: Olli P H Pietiläinen; Tiina Paunio; Anu Loukola; Annamari Tuulio-Henriksson; Tuula Kieseppä; Paul Thompson; Arthur W Toga; Theo G M van Erp; Karri Silventoinen; Pia Soronen; William Hennah; Joni A Turunen; Juho Wedenoja; Outi M Palo; Kaisa Silander; Jouko Lönnqvist; Jaakko Kaprio; Tyrone D Cannon; Leena Peltonen
Association of AKT1 with verbal learning, verbal memory, and regional cortical gray matter density in twins.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(5):683-92.
2009: Liisa Tomppo; William Hennah; Päivi Lahermo; Anu Loukola; Annamari Tuulio-Henriksson; Jaana Suvisaari; Timo Partonen; Jesper Ekelund; Jouko Lönnqvist; Leena Peltonen
Association between genes of Disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnesses.
Biological psychiatry 2009;65(12):1055-62.
2008: J Wedenoja; Anu Loukola; Annamari Tuulio-Henriksson; Tiina Paunio; Jesper Ekelund; Kaisa Silander; Teppo Varilo; K Heikkilä; Jaana Suvisaari; Timo Partonen; Jouko Lönnqvist; Leena Peltonen
Replication of linkage on chromosome 7q22 and association of the regional Reelin gene with working memory in schizophrenia families.
Molecular psychiatry 2008;13(7):673-84.
2008: Anu Loukola; U Broms; H Maunu; Elisabeth Widén; K Heikkilä; M Siivola; A Salo; M L Pergadia; E Nyman; Sampo Sammalisto; Markus Perola; A Agrawal; A C Heath; Nicholas G Martin; P A F Madden; Leena Peltonen; Jaakko Kaprio
Linkage of nicotine dependence and smoking behavior on 10q, 7q and 11p in twins with homogeneous genetic background.
The pharmacogenomics journal 2008;8(3):209-19.
2007: Emma S Nyman; Matthew N Ogdie; Anu Loukola; Teppo Varilo; Anja Taanila; Tuula Hurtig; Irma Moilanen; Sandra K Loo; James J McGough; Marjo-Riitta Järvelin; Susan L Smalley; Stanley F Nelson; Leena Peltonen
ADHD candidate gene study in a population-based birth cohort: association with DBH and DRD2.
Journal of the American Academy of Child and Adolescent Psychiatry 2007;46(12):1614-21.
2007: Scott F Saccone; Michele L Pergadia; Anu Loukola; Ulla Broms; Grant W Montgomery; Jen C Wang; Arpana Agrawal; Danielle M Dick; Andrew C Heath; Alexandre A Todorov; Heidi Maunu; Kauko Heikkilä; Katherine Morley; John P Rice; Richard D Todd; Jaakko Kaprio; Leena Peltonen; Nicholas G Martin; Alison Goate; Pamela A F Madden
Genetic linkage to chromosome 22q12 for a heavy-smoking quantitative trait in two independent samples.
American journal of human genetics 2007;80(5):856-66.
2007: Joni A Turunen; Juho O Peltonen; Olli P H Pietiläinen; William Hennah; Anu Loukola; Tiina Paunio; Kaisa Silander; Jesper Ekelund; Teppo Varilo; Timo Partonen; Jouko Lönnqvist; Leena Peltonen
The role of DTNBP1, NRG1, and AKT1 in the genetics of schizophrenia in Finland.
Schizophrenia research 2007;91(1-3):27-36.
2006: Marek Minarik; Lucie Benesova; Lucie Fantova; Jiri Horacek; Jiri Heracek; Anu Loukola
Parallel optimization and genotyping of multiple single-nucleotide polymorphism markers by sample pooling approach using cycling-gradient CE with multiple injections.
Electrophoresis 2006;27(19):3856-63.
2004: Anu Loukola; Monica Chadha; Sharron G Penn; David R Rank; David V Conti; Deborah Thompson; Mine S Cicek; Brad Love; Vesna Bivolarevic; Qiner Yang; Yalin Jiang; David K Hanzel; Katherine Dains; Pamela L Paris; Graham Casey; John S Witte
Comprehensive evaluation of the association between prostate cancer and genotypes/haplotypes in CYP17A1, CYP3A4, and SRD5A2.
European journal of human genetics : EJHG 2004;12(4):321-32.
2002: Xiao-Ping Zhou; Anu Loukola; Reijo Salovaara; Minna Nystrom-Lahti; Päivi Peltomäki; Albert de La Chapelle; Lauri A Aaltonen; Charis Eng
PTEN mutational spectra, expression levels, and subcellular localization in microsatellite stable and unstable colorectal cancers.
The American journal of pathology 2002;161(2):439-47.
2002: Reijo Salovaara; S Roth; Anu Loukola; Virpi Launonen; Pertti Sistonen; E Avizienyte; Paula Kristo; Heikki Järvinen; S Souchelnytskyi; Maarit Sarlomo-Rikala; Lauri A Aaltonen
Frequent loss of SMAD4/DPC4 protein in colorectal cancers.
Gut 2002;51(1):56-9.
2001: Sima Salahshor; H Hou; Chieu B Diep; Anu Loukola; H Zhang; T Liu; Jindong Chen; Lennart Iselius; C Rubio; R A Lothe; L Aaltonen; X F Sun; G Lindmark; Annika Lindblom
A germline E-cadherin mutation in a family with gastric and colon cancer.
International journal of molecular medicine 2001;8(4):439-43.
2001: Anu Loukola; K Eklin; Päivi Laiho; Reijo Salovaara; Paula Kristo; Heikki Järvinen; Jukka-Pekka Mecklin; Virpi Launonen; Lauri A Aaltonen
Microsatellite marker analysis in screening for hereditary nonpolyposis colorectal cancer (HNPCC).
Cancer research 2001;61(11):4545-9.
2001: Susa Vilkki; J L Tsao; Anu Loukola; Minna Pöyhönen; Outi Vierimaa; Riitta Herva; Lauri A Aaltonen; D Shibata
Extensive somatic microsatellite mutations in normal human tissue.
Cancer research 2001;61(11):4541-4.
2001: Ying Zhu; Anu Loukola; Outi Monni; K Kuokkanen; Kaarle Franssila; Erkki Elonen; Juhani Vilpo; Heikki Joensuu; Juha Kere; L Aaltonen; Sakari Knuutila
PPP2R1B gene in chronic lymphocytic leukemias and mantle cell lymphomas.
Leukemia & lymphoma 2001;41(1-2):177-83.
2000: Anu Loukola; Susa Vilkki; J Singh; Virpi Launonen; Lauri A Aaltonen
Germline and somatic mutation analysis of MLH3 in MSI-positive colorectal cancer.
The American journal of pathology 2000;157(2):347-52.
2000: Reijo Salovaara; Anu Loukola; Paula Kristo; Helena Kääriäinen; H Ahtola; Matti Eskelinen; N Härkönen; Risto Julkunen; E Kangas; S Ojala; J Tulikoura; E Valkamo; Heikki Järvinen; Jukka-Pekka Mecklin; Lauri A Aaltonen; Albert de La Chapelle
Population-based molecular detection of hereditary nonpolyposis colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(11):2193-200.
2000: S Roth; M Johansson; Anu Loukola; Päivi Peltomäki; Heikki Järvinen; Jukka-Pekka Mecklin; Lauri A Aaltonen
Mutation analysis of SMAD2, SMAD3, and SMAD4 genes in hereditary non-polyposis colorectal.
Journal of medical genetics 2000;37(4):298-300.
2000: Virpi Launonen; E Avizienyte; Anu Loukola; Päivi Laiho; Reijo Salovaara; Heikki Järvinen; Jukka-Pekka Mecklin; A Oku; Miyuki Shimane; H C Kim; J C Kim; Jun-ichi Nezu; Lauri A Aaltonen
No evidence of Peutz-Jeghers syndrome gene LKB1 involvement in left-sided colorectal carcinomas.
Cancer research 2000;60(3):546-8.
1999: Anu Loukola; Reijo Salovaara; Paula Kristo; Anu-Liisa Moisio; Helena Kääriäinen; H Ahtola; Matti Eskelinen; N Härkönen; Risto Julkunen; E Kangas; S Ojala; J Tulikoura; E Valkamo; Heikki Järvinen; Jukka-Pekka Mecklin; Albert de La Chapelle; Lauri A Aaltonen
Microsatellite instability in adenomas as a marker for hereditary nonpolyposis colorectal cancer.
The American journal of pathology 1999;155(6):1849-53.
1999: A Riccio; Lauri A Aaltonen; A K Godwin; Anu Loukola; Antonio Percesepe; Reijo Salovaara; Valeria Masciullo; Maurizio Genuardi; M Paravatou-Petsotas; Daniel E Bassi; B A Ruggeri; Andres Klein-Szanto; J R Testa; Giovanni Neri; Alfonso Bellacosa
The DNA repair gene MBD4 (MED1) is mutated in human carcinomas with microsatellite instability.
Nature genetics 1999;23(3):266-8.
1999: Anu Loukola; Albert de La Chapelle; Lauri A Aaltonen
Strategies for screening for hereditary non-polyposis colorectal cancer.
Journal of medical genetics 1999;36(11):819-22.
1999: S Roth; Pertti Sistonen; Reijo Salovaara; Akseli Hemminki; Anu Loukola; M Johansson; E Avizienyte; K A Cleary; P Lynch; C I Amos; Paula Kristo; Jukka-Pekka Mecklin; Ilmo Kellokumpu; Heikki Järvinen; Lauri A Aaltonen
SMAD genes in juvenile polyposis.
Genes, chromosomes & cancer 1999;26(1):54-61.
1999: E Avizienyte; Anu Loukola; S Roth; Akseli Hemminki; Maija Tarkkanen; Reijo Salovaara; Johanna Arola; Ralf Bützow; Kirsti Husgafvel-Pursiainen; Arto Kokkola; Heikki Järvinen; Lauri A Aaltonen
LKB1 somatic mutations in sporadic tumors.
The American journal of pathology 1999;154(3):677-81.
1999: Antti Ylikorkala; E Avizienyte; Ian P M Tomlinson; Marjaana Tiainen; S Roth; Anu Loukola; Akseli Hemminki; M Johansson; Pertti Sistonen; D Markie; Kay Neale; Robin Phillips; P Zauber; T Twama; J Sampson; Heikki Järvinen; Tomi Mäkelä; Lauri A Aaltonen
Mutations and impaired function of LKB1 in familial and non-familial Peutz-Jeghers syndrome and a sporadic testicular cancer.
Human molecular genetics 1999;8(1):45-51.
1999: Thomas W Prior; R B Chadwick; Audrey C Papp; A N Arcot; A M Isa; Dennis K Pearl; G Stemmermann; Antonio Percesepe; Anu Loukola; Lauri A Aaltonen; Albert de La Chapelle
The I1307K polymorphism of the APC gene in colorectal cancer.
Gastroenterology 1999;116(1):58-63.
1998: E Avizienyte; S Roth; Anu Loukola; Akseli Hemminki; Ragnhild A Lothe; Anna E Stenwig; Sophie D Fosså; Reijo Salovaara; Lauri A Aaltonen
Somatic mutations in LKB1 are rare in sporadic colorectal and testicular tumors.
Cancer research 1998;58(10):2087-90.
1998: Akseli Hemminki; D Markie; Ian Tomlinson; E Avizienyte; S Roth; Anu Loukola; Graham R Bignell; William Warren; M Aminoff; Pia Höglund; Heikki Järvinen; Paula Kristo; Katarina Pelin; Maaret Ridanpää; Reijo Salovaara; T Toro; Walter Bodmer; S Olschwang; A S Olsen; Michael R Stratton; Albert de La Chapelle; Lauri A Aaltonen
A serine/threonine kinase gene defective in Peutz-Jeghers syndrome.
Nature 1998;391(6663):184-7.
1998: Akseli Hemminki; E Avizienyte; S Roth; Anu Loukola; Lauri A Aaltonen; Heikki Järvinen; Albert de La Chapelle
[A serine/threonine kinase gene defective in Peutz-Jeghers syndrome].
Duodecim; lääketieteellinen aikakauskirja 1998;114(7):667-8.