FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Malcolm Low

Research Profile

Living Beings

Chemicals & Drugs

Anatomy

Activities & Behaviors

Motor Activity

Disorders

Pituitary Neoplasms

Concepts & Ideas

Physiology

Conditioning, Operant

Co-author Network

Publications

TOP 3
Daniela Noaín; Marcela Peper; M Inés Pérez-Millán; Damasia Becú-Villalobos; Estefanía P Bello; Rodrigo Casas Cordero; Diego M Gelman; Malcolm J Low; Guillermina M Luque; Isabel García Tornadu; Marcelo Rubinstein
Central dopamine D2 receptors regulate growth-hormone-dependent body growth and pheromone signaling to conspecific males.
Aaron J Mercer; Charles K Meshul; Shane T Hentges; Malcolm J Low
Unraveling the central proopiomelanocortin neural circuits.
Malcolm J Low
Mouse models in gastroenterology research.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Malcolm Low (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Daniela Noaín; Marcela Peper; M Inés Pérez-Millán; Damasia Becú-Villalobos; Estefanía P Bello; Rodrigo Casas Cordero; Diego M Gelman; Malcolm J Low; Guillermina M Luque; Isabel García Tornadu; Marcelo Rubinstein
Central dopamine D2 receptors regulate growth-hormone-dependent body growth and pheromone signaling to conspecific males.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013;33(13):5834-42.
2013: Aaron J Mercer; Charles K Meshul; Shane T Hentges; Malcolm J Low
Unraveling the central proopiomelanocortin neural circuits.
Frontiers in neuroscience 2013;7():19.
2012: Malcolm J Low
Mouse models in gastroenterology research.
Gastroenterology 2012;143(6):1410-2.
2012: Viviana F Bumaschny; Rodrigo Casas-Cordero; Flávio S J De Souza; Verónica Otero-Corchón; Marcelo Rubinstein; Miho Yamashita; Malcolm J Low
Obesity-programmed mice are rescued by early genetic intervention.
The Journal of clinical investigation 2012;122(11):4203-12.
2011: Lucía F Franchini; Diego M Gelman; Rodrigo Lopez-Leal; Malcolm J Low; Sofía Nasif; Paula Beati; Flávio J S de Souza; Marcelo Rubinstein
Convergent evolution of two mammalian neuronal enhancers by sequential exaptation of unrelated retroposons.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(37):15270-5.
2011: Marcelo Rubinstein; Malcolm J Low
The smoking gun in nicotine-induced anorexia.
Cell metabolism 2011;14(2):145-7.
2011: Estefanía P Bello; Diego M Gelman; David M Lovinger; Malcolm J Low; Yolanda Mateo; Daniela Noaín; Verónica A Alvarez; JUNG SHIN; Marcelo Rubinstein
Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors.
Nature neuroscience 2011;14(8):1033-8.
2011: Christian D Richard; Virginie Tolle; Malcolm J Low
Meal pattern analysis in neural-specific proopiomelanocortin-deficient mice.
European journal of pharmacology 2011;660(1):131-8.
2011: Flávio S J De Souza; Sofia Nasif; Rodrigo Lopez-Leal; Diego H Levi; Malcolm J Low; Marcelo Rubinsten
The estrogen receptor α colocalizes with proopiomelanocortin in hypothalamic neurons and binds to a conserved motif present in the neuron-specific enhancer nPE2.
European journal of pharmacology 2011;660(1):181-7.
2011: Malcolm J Low
Agnostic about in vivo inverse agonism of agouti-related peptide.
Endocrinology 2011;152(5):1731-3.
2011: Andy K Lee; James L Smart; Marcelo Rubinstein; Malcolm J Low; Amy Tse
Reciprocal regulation of TREK-1 channels by arachidonic acid and CRH in mouse corticotropes.
Endocrinology 2011;152(5):1901-10.
2010: Shannon K Gallagher; Paul Witkovsky; Michel J Roux; Malcolm J Low; Veronica Otero-Corchon; Shane T Hentges; Jozsef Vigh
beta-Endorphin expression in the mouse retina.
The Journal of comparative neurology 2010;518(15):3130-48.
2010: Isabel García-Tornadu; Gabriela Risso; Maria Ines Perez-Millan; Daniela Noain; Graciela Diaz-Torga; Malcolm J Low; Marcelo Rubinstein; Damasia Becu-Villalobos
Neurotransmitter modulation of the GHRH-GH axis.
Frontiers of hormone research 2010;38():59-69.
2009: Malcolm J Low
A tale of two carboxypeptidases.
Cell metabolism 2009;10(5):339-41.
2009: Shane T Hentges; Veronica Otero-Corchon; Reagan L Pennock; Connie M King; Malcolm J Low
Proopiomelanocortin expression in both GABA and glutamate neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(43):13684-90.
2009: Isabel García-Tornadú; Graciela Díaz-Torga; G S Risso; Patricia Silveyra; N Cataldi; M C Ramirez; Malcolm J Low; Carlos Libertun; Damasia Becu-Villalobos
Hypothalamic orexin, OX1, alphaMSH, NPY and MCRs expression in dopaminergic D2R knockout mice.
Neuropeptides 2009;43(4):267-74.
2009: Amanda L Sharpe; Malcolm J Low
Proopiomelanocortin peptides are not essential for development of ethanol-induced behavioral sensitization.
Alcoholism, clinical and experimental research 2009;33(7):1202-7.
2009: Astrid C Hauge-Evans; Aileen J King; Danielle Carmignac; Carolyn C Richardson; Iain C A F Robinson; Malcolm J Low; Michael R Christie; Shanta J Persaud; Peter M Jones
Somatostatin secreted by islet delta-cells fulfills multiple roles as a paracrine regulator of islet function.
Diabetes 2009;58(2):403-11.
2008: Seksiri Arttamangkul; Nidia Quillinan; Malcolm J Low; Mark von Zastrow; John Pintar; John T Williams
Differential activation and trafficking of micro-opioid receptors in brain slices.
Molecular pharmacology 2008;74(4):972-9.
2008: James M Doherty; Virginia L Masten; Susan B Powell; RJ Ralph; Daniel Klamer; Malcolm J Low; Mark A Geyer
Contributions of dopamine D1, D2, and D3 receptor subtypes to the disruptive effects of cocaine on prepulse inhibition in mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2008;33(11):2648-56.
2008: Lijie Gong; Fayi Yao; Kristin Hockman; Hong-Qiang Heng; Gregory J Morton; Kiyoshi Takeda; Shizuo Akira; Malcolm J Low; Marcelo Rubinstein; Robert George MacKenzie
Signal transducer and activator of transcription-3 is required in hypothalamic agouti-related protein/neuropeptide Y neurons for normal energy homeostasis.
Endocrinology 2008;149(7):3346-54.
2008: M A Kelly; Malcolm J Low; Marcelo Rubinstein; Tamara J Phillips
Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice.
Genes, brain, and behavior 2008;7(5):568-77.
2008: Virginie Tolle; Malcolm J Low
In vivo evidence for inverse agonism of Agouti-related peptide in the central nervous system of proopiomelanocortin-deficient mice.
Diabetes 2008;57(1):86-94.
2007: Suzanne M Appleyard; Daniel L Marks; Kazuto Kobayashi; Hideyuki Okano; Malcolm J Low; Michael Andresen
Visceral afferents directly activate catecholamine neurons in the solitary tract nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(48):13292-302.
2007: Viviana F Bumaschny; Flávio S J De Souza; Rodrigo Lopez-Leal; Andrea M Santangelo; Manfred Baetscher; Diego H Levi; Malcolm J Low; Marcelo Rubinstein
Transcriptional regulation of pituitary POMC is conserved at the vertebrate extremes despite great promoter sequence divergence.
Molecular endocrinology (Baltimore, Md.) 2007;21(11):2738-49.
2007: Andrea M Santangelo; Flávio S J De Souza; Lucía F Franchini; Viviana F Bumaschny; Malcolm J Low; Marcelo Rubinstein
Ancient exaptation of a CORE-SINE retroposon into a highly conserved mammalian neuronal enhancer of the proopiomelanocortin gene.
PLoS genetics 2007;3(10):1813-26.
2007: Michael Petraschka; Shuang Li; T L Gilbert; Ruth E Westenbroek; Michael R Bruchas; S Schreiber; Janet Lowe; Malcolm J Low; John E Pintar; Charles Chavkin
The absence of endogenous beta-endorphin selectively blocks phosphorylation and desensitization of mu opioid receptors following partial sciatic nerve ligation.
Neuroscience 2007;146(4):1795-807.
2007: Christiaan H Vinkers; Victoria B Risbrough; Mark A Geyer; Sorana Caldwell; Malcolm J Low; Richard L Hauger
Role of dopamine D1 and D2 receptors in CRF-induced disruption of sensorimotor gating.
Pharmacology, biochemistry, and behavior 2007;86(3):550-8.
2007: James L Smart; Virginie Tolle; Veronica Otero-Corchon; Malcolm J Low
Central dysregulation of the hypothalamic-pituitary-adrenal axis in neuron-specific proopiomelanocortin-deficient mice.
Endocrinology 2007;148(2):647-59.
2007: Michael Hayward; Malcolm J Low
The contribution of endogenous opioids to food reward is dependent on sex and background strain.
Neuroscience 2007;144(1):17-25.
2006: Michael Hayward; Alexandra Schaich-Borg; John E Pintar; Malcolm J Low
Differential involvement of endogenous opioids in sucrose consumption and food reinforcement.
Pharmacology, biochemistry, and behavior 2006;85(3):601-11.
2006: Victoria B Risbrough; Virginia L Masten; Sorana Caldwell; Martin P Paulus; Malcolm J Low; Mark A Geyer
Differential contributions of dopamine D1, D2, and D3 receptors to MDMA-induced effects on locomotor behavior patterns in mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(11):2349-58.
2006: Niki Mastrodimou; Anna Vasilaki; A Papadioti; Malcolm J Low; Daniel Hoyer; Kyriaki Thermos
Somatostatin receptors in wildtype and somatostatin deficient mice and their involvement in nitric oxide physiology in the retina.
Neuropeptides 2006;40(5):365-73.
2006: Isabel García-Tornadú; Marcelo Rubinstein; Bruce D Gaylinn; David Hill; Edith Arany; Malcolm J Low; Graciela Díaz-Torga; Damasia Becu-Villalobos
GH in the dwarf dopaminergic D2 receptor knockout mouse: somatotrope population, GH release, and responsiveness to GH-releasing factors and somatostatin.
The Journal of endocrinology 2006;190(3):611-9.
2006: Martin O Job; Vorani Ramachandra; Sheneil Anders; Malcolm J Low; Rueben A Gonzales
Reduced basal and ethanol stimulation of striatal extracellular dopamine concentrations in dopamine D2 receptor knockout mice.
Synapse (New York, N.Y.) 2006;60(2):158-64.
2006: T Rajendra Kumar; Kathryn G Schuff; Kevin D Nusser; Malcolm J Low
Gonadotroph-specific expression of the human follicle stimulating hormone beta gene in transgenic mice.
Molecular and cellular endocrinology 2006;247(1-2):103-15.
2006: James L Smart; Virginie Tolle; Malcolm J Low
Glucocorticoids exacerbate obesity and insulin resistance in neuron-specific proopiomelanocortin-deficient mice.
The Journal of clinical investigation 2006;116(2):495-505.
2006: Carolina Cristina; Isabel García-Tornadú; Graciela Díaz-Torga; Marcelo Rubinstein; Malcolm J Low; Damasia Becú-Villalobos
Dopaminergic D2 receptor knockout mouse: an animal model of prolactinoma.
Frontiers of hormone research 2006;35():50-63.
2006: Heldur Hakk; Janice K Huwe; Malcolm J Low; D Rutherford; Gerald Larsen
Tissue disposition, excretion and metabolism of 2,2',4,4',6-pentabromodiphenyl ether (BDE-100) in male Sprague-Dawley rats.
Xenobiotica; the fate of foreign compounds in biological systems 2006;36(1):79-94.
2006: Barbara A Cox; Malcolm J Low; Kim E Saunders; Charlotte Shupert
Should you count your mice before they're weaned? Start counting.
Lab animal 2006;35(1):17.
2005: Flávio S J De Souza; Viviana F Bumaschny; Malcolm J Low; Marcelo Rubinstein
Subfunctionalization of expression and peptide domains following the ancient duplication of the proopiomelanocortin gene in teleost fishes.
Molecular biology and evolution 2005;22(12):2417-27.
2005: Michael Hayward; Malcolm J Low
Naloxone's suppression of spontaneous and food-conditioned locomotor activity is diminished in mice lacking either the dopamine D(2) receptor or enkephalin.
Brain research. Molecular brain research 2005;140(1-2):91-8.
2005: Shane T Hentges; Malcolm J Low; John T Williams
Differential regulation of synaptic inputs by constitutively released endocannabinoids and exogenous cannabinoids.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(42):9746-51.
2005: Gregory I Elmer; Jeanne O Pieper; J Levy; M Rubinstein; Malcolm J Low; David K Grandy; R A Wise
Brain stimulation and morphine reward deficits in dopamine D2 receptor-deficient mice.
Psychopharmacology 2005;182(1):33-44.
2005: Carolina Cristina; Graciela Díaz-Torga; Alberto Baldi; A Góngora; Marcelo Rubinstein; Malcolm J Low; Damasia Becú-Villalobos
Increased pituitary vascular endothelial growth factor-a in dopaminergic D2 receptor knockout female mice.
Endocrinology 2005;146(7):2952-62.
2005: Suzanne M Appleyard; Timothy W Bailey; Mark W Doyle; Young-Ho Jin; James L Smart; Malcolm J Low; Michael Andresen
Proopiomelanocortin neurons in nucleus tractus solitarius are activated by visceral afferents: regulation by cholecystokinin and opioids.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(14):3578-85.
2005: Flávio S J De Souza; Andrea M Santangelo; Viviana F Bumaschny; María Elena Avale; James L Smart; Malcolm J Low; Marcelo Rubinstein
Identification of neuronal enhancers of the proopiomelanocortin gene by transgenic mouse analysis and phylogenetic footprinting.
Molecular and cellular biology 2005;25(8):3076-86.
2005: Andrzej Slominski; Przemyslaw Plonka; Alexander Pisarchik; James L Smart; Virginie Tolle; Jacobo Wortsman; Malcolm J Low
Preservation of eumelanin hair pigmentation in proopiomelanocortin-deficient mice on a nonagouti (a/a) genetic background.
Endocrinology 2005;146(3):1245-53.
2004: Malcolm J Low
Clinical endocrinology and metabolism. The somatostatin neuroendocrine system: physiology and clinical relevance in gastrointestinal and pancreatic disorders.
Best practice & research. Clinical endocrinology & metabolism 2004;18(4):607-22.
2004: Michael Hayward; Stephen T Hansen; John E Pintar; Malcolm J Low
Operant self-administration of ethanol in C57BL/6 mice lacking beta-endorphin and enkephalin.
Pharmacology, biochemistry, and behavior 2004;79(1):171-81.
2004: Mark W Doyle; Timothy W Bailey; Young-Ho Jin; Suzanne M Appleyard; Malcolm J Low; Michael Andresen
Strategies for cellular identification in nucleus tractus solitarius slices.
Journal of neuroscience methods 2004;137(1):37-48.
2004: María Elena Avale; Tomás L Falzone; Diego M Gelman; Malcolm J Low; David K Grandy; Marcelo Rubinstein
The dopamine D4 receptor is essential for hyperactivity and impaired behavioral inhibition in a mouse model of attention deficit/hyperactivity disorder.
Molecular psychiatry 2004;9(7):718-26.
2004: Linda S Overstreet; Shane T Hentges; Viviana F Bumaschny; Flávio S J De Souza; James L Smart; Andrea M Santangelo; Malcolm J Low; Gary L Westbrook; Marcelo Rubinstein
A transgenic marker for newly born granule cells in dentate gyrus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(13):3251-9.
2004: Shane T Hentges; Mitsuru Nishiyama; Linda S Overstreet; Mary P Stenzel-Poore; John T Williams; Malcolm J Low
GABA release from proopiomelanocortin neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(7):1578-83.
2004: Malcolm J Low
Role of proopiomelanocortin neurons and peptides in the regulation of energy homeostasis.
Journal of endocrinological investigation 2004;27(6 Suppl):95-100.
2004: Katsunori Tomiyama; Fergal N McNamara; Jeremiah J Clifford; Anthony Kinsella; John Drago; Sara Fuchs; David K Grandy; Malcolm J Low; Marcelo Rubinstein; Orna Tighe; David T Croke; Noriaki Koshikawa; John L Waddington
Comparative phenotypic resolution of spontaneous, D2-like and D1-like agonist-induced orofacial movement topographies in congenic mutants with dopamine D2 vs. D3 receptor "knockout".
Synapse (New York, N.Y.) 2004;51(1):71-81.
2003: Yana Zavros; Sivaprakash Rathinavelu; John Y Kao; Andrea Todisco; John Del Valle; Joel V Weinstock; Malcolm J Low; Juanita L Merchant
Treatment of Helicobacter gastritis with IL-4 requires somatostatin.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(22):12944-9.
2003: Michele A Kelly; Malcolm J Low; Tamara J Phillips; Edward K Wakeland; Masashi Yanagisawa
The mapping of quantitative trait loci underlying strain differences in locomotor activity between 129S6 and C57BL/6J mice.
Mammalian genome : official journal of the International Mammalian Genome Society 2003;14(10):692-702.
2003: Jonathan L Katz; Allison L Chausmer; Gregory I Elmer; Marcelo Rubinstein; Malcolm J Low; David K Grandy
Cocaine-induced locomotor activity and cocaine discrimination in dopamine D4 receptor mutant mice.
Psychopharmacology 2003;170(1):108-14.
2003: F Kuchenbauer; Marily Theodoropoulou; Ursula Hopfner; Johanna Stalla; Ulrich Renner; J C Tonn; Malcolm J Low; Eduardo Arzt; Günter K Stalla; Marcelo Páez-Pereda
Laminin inhibits lactotroph proliferation and is reduced in early prolactinoma development.
Molecular and cellular endocrinology 2003;207(1-2):13-20.
2003: Diego M Gelman; Daniela Noaín; María Elena Avale; Verónica Otero; Malcolm J Low; Marcelo Rubinstein
Transgenic mice engineered to target Cre/loxP-mediated DNA recombination into catecholaminergic neurons.
Genesis (New York, N.Y. : 2000) 2003;36(4):196-202.
2003: James L Smart; Malcolm J Low
Lack of proopiomelanocortin peptides results in obesity and defective adrenal function but normal melanocyte pigmentation in the murine C57BL/6 genetic background.
Annals of the New York Academy of Sciences 2003;994():202-10.
2003: Malcolm J Low; Michael Hayward; Suzanne M Appleyard; Marcelo Rubinstein
State-dependent modulation of feeding behavior by proopiomelanocortin-derived beta-endorphin.
Annals of the New York Academy of Sciences 2003;994():192-201.
2003: Lora K Heisler; Michael Alexander cowley; Toshiro Kishi; Laurence H Tecott; Wei Fan; Malcolm J Low; James L Smart; Marcelo Rubinstein; Jeffrey B Tatro; Jeffrey M Zigman; Roger D Cone; Joel K Elmquist
Central serotonin and melanocortin pathways regulating energy homeostasis.
Annals of the New York Academy of Sciences 2003;994():169-74.
2003: Abraham A Palmer; Malcolm J Low; David K Grandy; Tamara J Phillips
Effects of a Drd2 deletion mutation on ethanol-induced locomotor stimulation and sensitization suggest a role for epistasis.
Behavior genetics 2003;33(3):311-24.
2003: Suzanne M Appleyard; Michael Hayward; Juan I Young; Andrew A Butler; Roger D Cone; Marcelo Rubinstein; Malcolm J Low
A role for the endogenous opioid beta-endorphin in energy homeostasis.
Endocrinology 2003;144(5):1753-60.
2003: Nurhadi Ibrahim; Martha A Bosch; James L Smart; Jian Qiu; Marcelo Rubinstein; Oline K Ronnekleiv; Malcolm J Low; Martin J Kelly
Hypothalamic proopiomelanocortin neurons are glucose responsive and express K(ATP) channels.
Endocrinology 2003;144(4):1331-40.
2003: Michael Alexander cowley; Roy G Smith; Sabrina Diano; Matthias H Tschöp; Nina Pronchuk; Kevin L Grove; Christian J Strasburger; Martin Bidlingmaier; Michael Esterman; Mark L Heiman; Luis M Garcia-Segura; Eduardo A Nillni; Pablo Mendez; Malcolm J Low; Peter Sotonyi; Jeffrey M Friedman; Hongyan Liu; Shirly Pinto; William F Colmers; Roger D Cone; Tamas L Horvath
The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis.
Neuron 2003;37(4):649-61.
2003: Marcelo Paez-Pereda; Damiana Giacomini; Damian Refojo; Alberto Carbia Nagashima; Ursula Hopfner; Yvonne Grubler; Alberto Chervin; Victoria Goldberg; Rodolfo Goya; Shane T Hentges; Malcolm J Low; Florian Holsboer; Günter K Stalla; Eduardo Arzt
Involvement of bone morphogenetic protein 4 (BMP-4) in pituitary prolactinoma pathogenesis through a Smad/estrogen receptor crosstalk.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):1034-9.
2002: Shane T Hentges; Malcolm J Low
Ovarian dependence for pituitary tumorigenesis in D2 dopamine receptor-deficient mice.
Endocrinology 2002;143(12):4536-43.
2002: Rebecca J Ralph-Williams; Virginia Lehmann-Masten; Veronica Otero-Corchon; Malcolm J Low; Mark A Geyer
Differential effects of direct and indirect dopamine agonists on prepulse inhibition: a study in D1 and D2 receptor knock-out mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(21):9604-11.
2002: Damian Refojo; Damian Kovalovsky; Juan I Young; Marcelo Rubinstein; Florian Holsboer; Johannes M H M Reul; Malcolm J Low; Eduardo Arzt
Increased splenocyte proliferative response and cytokine production in beta-endorphin-deficient mice.
Journal of neuroimmunology 2002;131(1-2):126-34.
2002: Kathryn G Schuff; Shane T Hentges; Michele A Kelly; Nadine Binart; Paul A Kelly; P Michael Iuvone; Sylvia Asa; Malcolm J Low
Lack of prolactin receptor signaling in mice results in lactotroph proliferation and prolactinomas by dopamine-dependent and -independent mechanisms.
The Journal of clinical investigation 2002;110(7):973-81.
2002: Michael Hayward; John E Pintar; Malcolm J Low
Selective reward deficit in mice lacking beta-endorphin and enkephalin.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(18):8251-8.
2002: Rachel L Batterham; Michael Alexander cowley; Caroline J Small; Herbert Herzog; Mark A Cohen; Catherine L Dakin; Alison M Wren; Audrey E Brynes; Malcolm J Low; Mohammad A Ghatei; Roger D Cone; Stephen R Bloom
Gut hormone PYY(3-36) physiologically inhibits food intake.
Nature 2002;418(6898):650-4.
2002: Allison L Chausmer; Gregory I Elmer; Marcelo Rubinstein; Malcolm J Low; David K Grandy; Jonathan L Katz
Cocaine-induced locomotor activity and cocaine discrimination in dopamine D2 receptor mutant mice.
Psychopharmacology 2002;163(1):54-61.
2002: José L Ramírez; Rania Mouchantaf; Ujendra Kumar; Veronica Otero-Corchon; Marcelo Rubinstein; Malcolm J Low; Yogesh C Patel
Brain somatostatin receptors are up-regulated in somatostatin-deficient mice.
Molecular endocrinology (Baltimore, Md.) 2002;16(8):1951-63.
2002: Lora K Heisler; Michael Alexander cowley; Laurence H Tecott; Wei Fan; Malcolm J Low; James L Smart; Marcelo Rubinstein; Jeffrey B Tatro; Jacob N Marcus; Henne Holstege; Charlotte E Lee; Roger D Cone; Joel K Elmquist
Activation of central melanocortin pathways by fenfluramine.
Science (New York, N.Y.) 2002;297(5581):609-11.
2002: John W Ensinck; Denis Baskin; Torsten P Vahl; Robin E Vogel; Ellen C Laschansky; Bruce H Francis; Ross C Hoffman; Jonathan D Krakover; Michael R Stamm; Malcolm J Low; Marcelo Rubinstein; Veronica Otero-Corchon; David A D'Alessio
Thrittene, homologous with somatostatin-28((1-13)), is a novel peptide in mammalian gut and circulation.
Endocrinology 2002;143(7):2599-609.
2002: Gregory I Elmer; Jeanne O Pieper; Marcelo Rubinstein; Malcolm J Low; David K Grandy; Roy A Wise
Failure of intravenous morphine to serve as an effective instrumental reinforcer in dopamine D2 receptor knock-out mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(10):RC224.
2002: Graciela Díaz-Torga; C Feierstein; Carlos Libertun; D Gelman; M A Kelly; Malcolm J Low; Marcelo Rubinstein; Damasia Becú-Villalobos
Disruption of the D2 dopamine receptor alters GH and IGF-I secretion and causes dwarfism in male mice.
Endocrinology 2002;143(4):1270-9.
2002: Ye Lauren Liu; Shoshana Yakar; Veronica Otero-Corchon; Malcolm J Low; Jun Li Liu
Ghrelin gene expression is age-dependent and influenced by gender and the level of circulating IGF-I.
Molecular and cellular endocrinology 2002;189(1-2):97-103.
2002: Izhak Nir; Joseph Harrison; Rashidul Haque; Malcolm J Low; David K Grandy; Marcelo Rubinstein; P Michael Iuvone
Dysfunctional light-evoked regulation of cAMP in photoreceptors and abnormal retinal adaptation in mice lacking dopamine D4 receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(6):2063-73.
2002: Tomás L Falzone; Diego M Gelman; Juan I Young; David K Grandy; Malcolm J Low; Marcelo Rubinstein
Absence of dopamine D4 receptors results in enhanced reactivity to unconditioned, but not conditioned, fear.
The European journal of neuroscience 2002;15(1):158-64.
2002: Paul S Buckmaster; Veronica Otero-Corchón; Marcelo Rubinstein; Malcolm J Low
Heightened seizure severity in somatostatin knockout mice.
Epilepsy research 2002;48(1-2):43-56.
2002: Malcolm J Low
Pituitary adenomas in man and mouse: oncogenic potential of a truncated fibroblast growth factor receptor 4.
The Journal of clinical investigation 2002;109(1):15-6.
2001: Roger D Cone; Michael Alexander cowley; Andrew A Butler; Wei Fan; Daniel L Marks; Malcolm J Low
The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2001;25 Suppl 5():S63-7.
2001: Michael Hayward; Malcolm J Low
The effect of naloxone on operant behavior for food reinforcers in DBA/2 mice.
Brain research bulletin 2001;56(6):537-43.
2001: Jeremiah J Clifford; Anthony Kinsella; Orna Tighe; M Rubinstein; David K Grandy; Malcolm J Low; David T Croke; John L Waddington
Comparative, topographically-based evaluation of behavioural phenotype and specification of D(1)-like:D(2) interactions in a line of incipient congenic mice with D(2) dopamine receptor 'knockout'.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001;25(4):527-36.
2001: Sandrine Bertrand; Gordon Y K Ng; Maya Gadhvi Purisai; SE Wolfe; M W Severidt; D Nouel; Richard Robitaille; Malcolm J Low; Gary P O'Neill; Kathleen M Metters; Jean-Claude Lacaille; Bibie M Chronwall; SJ Morris
The anticonvulsant, antihyperalgesic agent gabapentin is an agonist at brain gamma-aminobutyric acid type B receptors negatively coupled to voltage-dependent calcium channels.
The Journal of pharmacology and experimental therapeutics 2001;298(1):15-24.
2001: Malcolm J Low; Veronica Otero-Corchon; A F Parlow; J L Ramirez; Ujendra Kumar; Yogesh C Patel; Marcelo Rubinstein
Somatostatin is required for masculinization of growth hormone-regulated hepatic gene expression but not of somatic growth.
The Journal of clinical investigation 2001;107(12):1571-80.
2001: Bibie M Chronwall; Tracy Dawn Davis; M W Severidt; SE Wolfe; Kenneth E McCarson; DM Beatty; Malcolm J Low; SJ Morris; SJ Enna
Constitutive expression of functional GABA(B) receptors in mIL-tsA58 cells requires both GABA(B(1)) and GABA(B(2)) genes.
Journal of neurochemistry 2001;77(5):1237-47.
2001: Marcelo Rubinstein; Carlos Cepeda; Raymond S Hurst; J Flores-Hernandez; Marjorie A Ariano; Tomás L Falzone; Laura B Kozell; Charles K Meshul; James R Bunzow; Malcolm J Low; Michael S Levine; David K Grandy
Dopamine D4 receptor-deficient mice display cortical hyperexcitability.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(11):3756-63.
2001: Michael Alexander cowley; J L Smart; M Rubinstein; M G Cerdán; Sabrina Diano; T L Horvath; Roger D Cone; Malcolm J Low
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus.
Nature 2001;411(6836):480-4.
2001: C L Dockstader; M Rubinstein; David K Grandy; Malcolm J Low; Derek van der Kooy
The D2 receptor is critical in mediating opiate motivation only in opiate-dependent and withdrawn mice.
The European journal of neuroscience 2001;13(5):995-1001.
2001: Jiang-Fan Chen; Rosario Moratalla; Francesco Impagnatiello; David K Grandy; Beatriz Cuellar; M Rubinstein; MA Beilstein; E Hackett; J Stephen Fink; Malcolm J Low; Ennio Ongini; Michael A Schwarzschild
The role of the D(2) dopamine receptor (D(2)R) in A(2A) adenosine receptor (A(2A)R)-mediated behavioral and cellular responses as revealed by A(2A) and D(2) receptor knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1970-5.
2001: Carlos Cepeda; Raymond S Hurst; KL Altemus; Jorge Flores-Hernández; Christopher R Calvert; Eve S Jokel; David K Grandy; Malcolm J Low; Marcelo Rubinstein; Marjorie A Ariano; Michael S Levine
Facilitated glutamatergic transmission in the striatum of D2 dopamine receptor-deficient mice.
Journal of neurophysiology 2001;85(2):659-70.
2001: K Tang; Malcolm J Low; David K Grandy; David M Lovinger
Dopamine-dependent synaptic plasticity in striatum during in vivo development.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(3):1255-60.
2000: Nicholas J Grahame; AK Mosemiller; Malcolm J Low; Janice C Froehlich
Naltrexone and alcohol drinking in mice lacking beta-endorphin by site-directed mutagenesis.
Pharmacology, biochemistry, and behavior 2000;67(4):759-66.
2000: Christopher L Cunningham; M A Howard; S J Gill; M Rubinstein; Malcolm J Low; David K Grandy
Ethanol-conditioned place preference is reduced in dopamine D2 receptor-deficient mice.
Pharmacology, biochemistry, and behavior 2000;67(4):693-9.
2000: Fred O Risinger; PA Freeman; M Rubinstein; Malcolm J Low; David K Grandy
Lack of operant ethanol self-administration in dopamine D2 receptor knockout mice.
Psychopharmacology 2000;152(3):343-50.
2000: Robert M Slugg; Michael Hayward; Oline K Ronnekleiv; Malcolm J Low; Martin J Kelly
Effect of the mu-opioid agonist DAMGO on medial basal hypothalamic neurons in beta-endorphin knockout mice.
Neuroendocrinology 2000;72(4):208-17.
2000: Kimberly A Huey; Malcolm J Low; M A Kelly; R Juarez; JM Szewczak; Frank L Powell
Ventilatory responses to acute and chronic hypoxia in mice: effects of dopamine D(2) receptors.
Journal of applied physiology (Bethesda, Md. : 1985) 2000;89(3):1142-50.
2000: Nancy R Zahniser; Johanna K Simosky; R Dayne Mayfield; CA Negri; Taleen Hanania; Gaynor A Larson; M A Kelly; David K Grandy; M Rubinstein; Malcolm J Low; Bertil B. Fredholm
Functional uncoupling of adenosine A(2A) receptors and reduced responseto caffeine in mice lacking dopamine D2 receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(16):5949-57.
2000: Kuei Tseng; Christine Roubert; L Do; Marcelo Rubinstein; M A Kelly; David K Grandy; Malcolm J Low; Oscar S Gershanik; M Gustavo Murer; Bruno GIROS; Rita Raisman-Vozari
Selective increase of Nurr1 mRNA expression in mesencephalic dopaminergic neurons of D2 dopamine receptor-deficient mice.
Brain research. Molecular brain research 2000;80(1):1-6.
2000: Sarah C Coste; R A Kesterson; KA Heldwein; Susan L Stevens; AD Heard; Jacob Hollis; Susan E Murray; Jennifer K Hill; George A Pantely; Alan Roger (Roger) Hohimer; D C Hatton; Tamara J Phillips; Deborah A Finn; Malcolm J Low; Marvin B Rittenberg; Peter Stenzel; Mary P Stenzel-Poore
Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2.
Nature genetics 2000;24(4):403-9.
2000: María C Defagot; Tomás L Falzone; Malcolm J Low; David K Grandy; Marcelo Rubinstein; Marta C Antonelli
Quantitative analysis of the dopamine D4 receptor in the mouse brain.
Journal of neuroscience research 2000;59(2):202-8.
2000: Jeffrey S Mogil; Judith E Grisel; Michael Hayward; J R Bales; M Rubinstein; John K Belknap; Malcolm J Low
Disparate spinal and supraspinal opioid antinociceptive responses in beta-endorphin-deficient mutant mice.
Neuroscience 2000;101(3):709-17.
2000: M Gustavo Murer; G Dziewczapolski; Pascal Salin; Miquel Vila; Kuei Tseng; Merle Ruberg; M Rubinstein; M A Kelly; David K Grandy; Malcolm J Low; Etienne C Hirsch; Rita Raisman-Vozari; Oscar S Gershanik
The indirect basal ganglia pathway in dopamine D(2) receptor-deficient mice.
Neuroscience 2000;99(4):643-50.
1999: Sylvia Asa; M A Kelly; David K Grandy; Malcolm J Low
Pituitary lactotroph adenomas develop after prolonged lactotroph hyperplasia in dopamine D2 receptor-deficient mice.
Endocrinology 1999;140(11):5348-55.
1999: Stephanie C Dulawa; David K Grandy; Malcolm J Low; Martin P Paulus; Mark A Geyer
Dopamine D4 receptor-knock-out mice exhibit reduced exploration of novel stimuli.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(21):9550-6.
1999: KE Graham; K D Nusser; Malcolm J Low
LbetaT2 gonadotroph cells secrete follicle stimulating hormone (FSH) in response to active A.
The Journal of endocrinology 1999;162(3):R1-5.
1999: Judith E Grisel; Jeffrey S Mogil; Nicholas J Grahame; M Rubinstein; John K Belknap; John C Crabbe; Malcolm J Low
Ethanol oral self-administration is increased in mutant mice with decreased beta-endorphin expression.
Brain research 1999;835(1):62-7.
1999: R J Ralph; Geoffrey Varty; M A Kelly; Y M Wang; Marc G Caron; M Rubinstein; David K Grandy; Malcolm J Low; Mark A Geyer
The dopamine D2, but not D3 or D4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(11):4627-33.
1999: RA Wilke; PJ Lupardus; David K Grandy; M Rubinstein; Malcolm J Low; Meyer B Jackson
K+ channel modulation in rodent neurohypophysial nerve terminals by sigma receptors and not by dopamine receptors.
The Journal of physiology 1999;517 ( Pt 2)():391-406.
1999: A Grewal; Sheri Bradshaw; Alwin G P Schuller; Malcolm J Low; John E Pintar
Expression of IGF system genes during T-antigen driven pituitary tumorigenesis.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1999;31(2-3):155-60.
1999: Michael Hayward; Malcolm J Low
Targeted mutagenesis of the murine opioid system.
Results and problems in cell differentiation 1999;26():169-91.
1999: SD Dickinson; Jilla Sabeti; Gaynor A Larson; KE Giardina; M Rubinstein; M A Kelly; David K Grandy; Malcolm J Low; Greg A Gerhardt; Nancy R Zahniser
Dopamine D2 receptor-deficient mice exhibit decreased dopamine transporter function but no changes in dopamine release in dorsal striatum.
Journal of neurochemistry 1999;72(1):148-56.
1998: Tamara J Phillips; K J Brown; Sue Burkhart-Kasch; Charlotte D Wenger; M A Kelly; Marcelo Rubinstein; David K Grandy; Malcolm J Low
Alcohol preference and sensitivity are markedly reduced in mice lacking dopamine D2 receptors.
Nature neuroscience 1998;1(7):610-5.
1998: Malcolm J Low; M A Kelly; M Rubinstein; David K Grandy
Single genes and complex phenotypes.
Molecular psychiatry 1998;3(5):373-7.
1998: Juan I Young; Verónica Otero; M G Cerdán; Tomás L Falzone; E C Chan; Malcolm J Low; Marcelo Rubinstein
Authentic cell-specific and developmentally regulated expression of pro-opiomelanocortin genomic fragments in hypothalamic and hindbrain neurons of transgenic mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(17):6631-40.
1998: Nicholas J Grahame; Malcolm J Low; Christopher L Cunningham
Intravenous self-administration of ethanol in beta-endorphin-deficient mice.
Alcoholism, clinical and experimental research 1998;22(5):1093-8.
1998: T Rajendra Kumar; K E Graham; Sylvia Asa; Malcolm J Low
Simian virus 40 T antigen-induced gonadotroph adenomas: a model of human null cell adenomas.
Endocrinology 1998;139(7):3342-51.
1998: T Rajendra Kumar; Malcolm J Low; Martin M Matzuk
Genetic rescue of follicle-stimulating hormone beta-deficient mice.
Endocrinology 1998;139(7):3289-95.
1998: M A Kelly; Marcelo Rubinstein; Tamara J Phillips; Christina N Lessov; Sue Burkhart-Kasch; G Zhang; James R Bunzow; Y Fang; G A Gerhardt; David K Grandy; Malcolm J Low
Locomotor activity in D2 dopamine receptor-deficient mice is determined by gene dosage, genetic background, and developmental adaptations.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(9):3470-9.
1997: Wenbiao Chen; M A Kelly; X Opitz-Araya; R E Thomas; Malcolm J Low; Roger D Cone
Exocrine gland dysfunction in MC5-R-deficient mice: evidence for coordinated regulation of exocrine gland function by melanocortin peptides.
Cell 1997;91(6):789-98.
1997: Robert Hnasko; S Khurana; N Shackleford; Rosemary Steinmetz; Malcolm J Low; Nira Ben-Jonathan
Two distinct pituitary cell lines from mouse intermediate lobe tumors: a cell that produces prolactin-regulating factor and a melanotroph [seecomments].
Endocrinology 1997;138(12):5589-96.
1997: Marcelo Rubinstein; Tamara J Phillips; James R Bunzow; Tomás L Falzone; G Dziewczapolski; G Zhang; Y Fang; J L Larson; J A McDougall; J A Chester; C Saez; T A Pugsley; Oscar S Gershanik; Malcolm J Low; David K Grandy
Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine.
Cell 1997;90(6):991-1001.
1997: M A Kelly; M Rubinstein; Sylvia Asa; G Zhang; C Saez; James R Bunzow; Richard G Allen; Robert Hnasko; Nira Ben-Jonathan; David K Grandy; Malcolm J Low
Pituitary lactotroph hyperplasia and chronic hyperprolactinemia in dopamine D2 receptor-deficient mice.
Neuron 1997;19(1):103-13.
1996: M A Whitney; G Royle; Malcolm J Low; M A Kelly; Michael K Axthelm; Carol A Reifsteck; Susan B Olson; R E Braun; Michael C Heinrich; R Keaney Rathbun; Grover C Bagby; Markus Grompe
Germ cell defects and hematopoietic hypersensitivity to gamma-interferon in mice with a targeted disruption of the Fanconi anemia C gene.
Blood 1996;88(1):49-58.
1996: M Rubinstein; Jeffrey S Mogil; M Japón; E C Chan; R G Allen; Malcolm J Low
Absence of opioid stress-induced analgesia in mice lacking beta-endorphin by site-directed mutagenesis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):3995-4000.
1995: B Liu; M Mortrud; Malcolm J Low
DNA elements with AT-rich core sequences direct pituitary cell-specific expression of the pro-opiomelanocortin gene in transgenic mice.
The Biochemical journal 1995;312 ( Pt 3)():827-32.
1995: T Rajendra Kumar; M Kelly; M Mortrud; Malcolm J Low; Martin M Matzuk
Cloning of the mouse gonadotropin beta-subunit-encoding genes, I. Structure of the follicle-stimulating hormone beta-subunit-encoding gene.
Gene 1995;166(2):333-4.
1995: R G Allen; C Carey; J D Parker; M T Mortrud; Synthia H Mellon; Malcolm J Low
Targeted ablation of pituitary pre-proopiomelanocortin cells by herpes simplex virus-1 thymidine kinase differentially regulates mRNAs encoding the adrenocorticotropin receptor and aldosterone synthase in the mouse adrenal gland.
Molecular endocrinology (Baltimore, Md.) 1995;9(8):1005-16.
1995: D L Allen; Malcolm J Low; R G Allen; Nira Ben-Jonathan
Identification of two classes of prolactin-releasing factors in intermediate lobe tumors from transgenic mice.
Endocrinology 1995;136(7):3093-9.
1995: T Rajendra Kumar; Malcolm J Low
Hormonal regulation of human follicle-stimulating hormone-beta subunit gene expression: GnRH stimulation and GnRH-independent androgen inhibition.
Neuroendocrinology 1995;61(6):628-37.
1994: K G Mountjoy; M T Mortrud; Malcolm J Low; R B Simerly; Roger D Cone
Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain.
Molecular endocrinology (Baltimore, Md.) 1994;8(10):1298-308.
1994: M A Japón; M Rubinstein; Malcolm J Low
In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1994;42(8):1117-25.
1994: James R Bunzow; C Saez; M Mortrud; C Bouvier; John T Williams; Malcolm J Low; David K Grandy
Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type.
FEBS letters 1994;347(2-3):284-8.
1993: Malcolm J Low; B Liu; Gary Hammer; M Rubinstein; R G Allen
Post-translational processing of proopiomelanocortin (POMC) in mouse pituitary melanotroph tumors induced by a POMC-simian virus 40 large T antigen transgene.
The Journal of biological chemistry 1993;268(33):24967-75.
1993: L Roselli-Rehfuss; K G Mountjoy; L S Robbins; M T Mortrud; Malcolm J Low; Jeffrey B Tatro; M L Entwistle; R B Simerly; Roger D Cone
Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(19):8856-60.
1993: M Rubinstein; M Mortrud; B Liu; Malcolm J Low
Rat and mouse proopiomelanocortin gene sequences target tissue-specific expression to the pituitary gland but not to the hypothalamus of transgenic mice.
Neuroendocrinology 1993;58(4):373-80.
1993: T Rajendra Kumar; Malcolm J Low
Gonadal steroid hormone regulation of human and mouse follicle stimulating hormone beta-subunit gene expression in vivo.
Molecular endocrinology (Baltimore, Md.) 1993;7(7):898-906.
1993: M Rubinstein; M A Japón; Malcolm J Low
Introduction of a point mutation into the mouse genome by homologous recombination in embryonic stem cells using a replacement type vector with a selectable marker.
Nucleic acids research 1993;21(11):2613-7.
1992: M Feinmesser; Sylvia Asa; K Kovacs; Malcolm J Low
Fine structure of adrenal cortex in rats harbouring a medullary thyroid carcinoma transfected with a corticotrophin-releasing hormone cDNA expression vector.
The Journal of endocrinology 1992;135(2):271-7.
1992: B Liu; Gary Hammer; M Rubinstein; M Mortrud; Malcolm J Low
Identification of DNA elements cooperatively activating proopiomelanocortin gene expression in the pituitary glands of transgenic mice.
Molecular and cellular biology 1992;12(9):3978-90.
1992: Sylvia Asa; K Kovacs; Gary Hammer; B Liu; Bernard A Roos; Malcolm J Low
Pituitary corticotroph hyperplasia in rats implanted with a medullary thyroid carcinoma cell line transfected with a corticotropin-releasing hormone complementary deoxyribonucleic acid expression vector.
Endocrinology 1992;131(2):715-20.
1992: M Rubinstein; B Liu; Richard H Goodman; Malcolm J Low
Targeted expression of somatostatin in vasopressinergic magnocellular hypothalamic neurons of transgenic mice.
Molecular and cellular neurosciences 1992;3(2):152-61.
1992: Gary Hammer; G Mueller; B Liu; J S Petrides; Bernard A Roos; Malcolm J Low
Ectopic corticotropin-releasing hormone produced by a transfected cell line chronically activates the pituitary-adrenal axis in transkaryotic rats.
Endocrinology 1992;130(4):1975-85.
1992: T Rajendra Kumar; V Fairchild-Huntress; Malcolm J Low
Gonadotrope-specific expression of the human follicle-stimulating hormone beta-subunit gene in pituitaries of transgenic mice.
Molecular endocrinology (Baltimore, Md.) 1992;6(1):81-90.
1990: Gary Hammer; V Fairchild-Huntress; Malcolm J Low
Pituitary-specific and hormonally regulated gene expression directed by the rat proopiomelanocortin promoter in transgenic mice.
Molecular endocrinology (Baltimore, Md.) 1990;4(11):1689-97.
1990: Richard H Goodman; R P Rehfuss; M Verhave; R Ventimiglia; Malcolm J Low
Somatostatin gene regulation: an overview.
Metabolism: clinical and experimental 1990;39(9 Suppl 2):2-5.
1989: Malcolm J Low; Richard H Goodman; K M Ebert
Cryptic human growth hormone gene sequences direct gonadotroph-specific expression in transgenic mice.
Molecular endocrinology (Baltimore, Md.) 1989;3(12):2028-33.
1988: K M Ebert; Malcolm J Low; Eric Overstrom; F C Buonomo; Clifton A Baile; Thomas M Roberts; A Lee; Gail Mandel; Richard H Goodman
A Moloney MLV-rat somatotropin fusion gene produces biologically active somatotropin in a transgenic pig.
Molecular endocrinology (Baltimore, Md.) 1988;2(3):277-83.
1987: K A Sevarino; R Felix; C M Banks; Malcolm J Low; M R Montminy; Gail Mandel; Richard H Goodman
Cell-specific processing of preprosomatostatin in cultured neuroendocrine cells.
The Journal of biological chemistry 1987;262(11):4987-93.
1987: Richard H Goodman; Andrew B Leiter; Malcolm J Low; M R Montminy; T Tsukada; J Stephen Fink; Gail Mandel
Biosynthesis of pancreatic islet hormones.
Hepatology (Baltimore, Md.) 1987;7(1 Suppl):36S-41S.
1986: Malcolm J Low; Philip J S Stork; R E Hammer; R L Brinster; M J Warhol; Gail Mandel; Richard H Goodman
Somatostatin is targeted to the regulated secretory pathway of gonadotrophs in transgenic mice expressing a metallothionein-somatostatin gene.
The Journal of biological chemistry 1986;261(34):16260-3.
1986: M R Montminy; Malcolm J Low; L Tapia-Arancibia; S Reichlin; Gail Mandel; Richard H Goodman
Cyclic AMP regulates somatostatin mRNA accumulation in primary diencephalic cultures and in transfected fibroblast cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1986;6(4):1171-6.
1986: Malcolm J Low; R M Lechan; R E Hammer; R L Brinster; J F Habener; Gail Mandel; Richard H Goodman
Gonadotroph-specific expression of metallothionein fusion genes in pituitaries of transgenic mice.
Science (New York, N.Y.) 1986;231(4741):1002-4.
1985: Malcolm J Low; R E Hammer; Richard H Goodman; J F Habener; R D Palmiter; R L Brinster
Tissue-specific posttranslational processing of pre-prosomatostatin encoded by a metallothionein-somatostatin fusion gene in transgenic mice.
Cell 1985;41(1):211-9.
1985: Richard H Goodman; M R Montminy; Malcolm J Low; J F Habener
Biosynthesis of rat preprosomatostatin.
Advances in experimental medicine and biology 1985;188():31-47.
1984: Malcolm J Low; Richard H Goodman; R L Brinster; R D Palmiter; R E Hammer; J F Habener
High plasma levels of immunoreactive somatostatin in transgenic mice expressing a metallothionein-somatostatin fusion gene.
Transactions of the Association of American Physicians 1984;97():205-9.