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John Lowe

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David Yao; Yuanshuai Huang; Xiaoran Huang; Weihuan Wang; Quanjian Yan; Lebing Wei; Wei Xin; Stanton Gerson; Pamela Stanley; John B Lowe; Lan Zhou
Protein O-fucosyltransferase 1 (Pofut1) regulates lymphoid and myeloid homeostasis through modulation of Notch receptor ligand interactions.
Quanjian Yan; David Yao; Lebing L Wei; Yuanshuai Huang; Jay Myers; Lihua Zhang; Wei Xin; Jeongsup Shim; Yunfang Man; Bronislawa Petryniak; Stanton Gerson; John B Lowe; Lan Zhou
O-fucose modulates Notch-controlled blood lineage commitment.
Rose C Beck; Mallika Padival; David Yeh; Justine Ralston; Kenneth R Cooke; John B Lowe
The Notch ligands Jagged2, Delta1, and Delta4 induce differentiation and expansion of functional human NK cells from CD34+ cord blood hematopoietic progenitor cells.

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2011: David Yao; Yuanshuai Huang; Xiaoran Huang; Weihuan Wang; Quanjian Yan; Lebing Wei; Wei Xin; Stanton Gerson; Pamela Stanley; John B Lowe; Lan Zhou
Protein O-fucosyltransferase 1 (Pofut1) regulates lymphoid and myeloid homeostasis through modulation of Notch receptor ligand interactions.
Blood 2011;117(21):5652-62.
2010: Quanjian Yan; David Yao; Lebing L Wei; Yuanshuai Huang; Jay Myers; Lihua Zhang; Wei Xin; Jeongsup Shim; Yunfang Man; Bronislawa Petryniak; Stanton Gerson; John B Lowe; Lan Zhou
O-fucose modulates Notch-controlled blood lineage commitment.
The American journal of pathology 2010;176(6):2921-34.
2009: Rose C Beck; Mallika Padival; David Yeh; Justine Ralston; Kenneth R Cooke; John B Lowe
The Notch ligands Jagged2, Delta1, and Delta4 induce differentiation and expansion of functional human NK cells from CD34+ cord blood hematopoietic progenitor cells.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2009;15(9):1026-37.
2009: Kishore Guda; Helen Moinova; Jian He; Oliver Jamison; Lakshmeswari Ravi; Leanna Natale; James Lutterbaugh; Earl Lawrence; Susan Lewis; James Willson; John B Lowe; Georgia L Wiesner; Giovanni Parmigiani; Jill S Barnholtz-Sloan; Dawn W Dawson; Victor E Velculescu; Kenneth W Kinzler; Nickolas Papadopoulos; Bert Vogelstein; Joseph Willis; Thomas A Gerken; Sanford D Markowitz
Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(31):12921-5.
2009: Tianju Liu; Biao Hu; Yoon Young Choi; Myoungja Chung; Matt Ullenbruch; Hongfeng Yu; John B Lowe; Sem H Phan
Notch1 signaling in FIZZ1 induction of myofibroblast differentiation.
The American journal of pathology 2009;174(5):1745-55.
2008: Paolo Fabene; Graciela Navarro Mora; Marianna Martinello; Barbara Rossi; Flavia Merigo; Linda Ottoboni; Simona Bach; Stefano Angiari; Donatella Benati; Asmaa Chakir; Lara Zanetti; Federica Schio; Antonio Osculati; Pasquina Marzola; Elena Nicolato; Jonathon W Homeister; Lijun Xia; John B Lowe; Rodger P McEver; Francesco Osculati; Andrea Sbarbati; Eugene C Butcher; Gabriela Constantin
A role for leukocyte-endothelial adhesion mechanisms in epilepsy.
Nature medicine 2008;14(12):1377-83.
2008: Ajit Varki; Linda G Baum; Susan L Bellis; Richard D Cummings; Jeffrey D Esko; Gerald W Hart; Robert J Linhardt; John B Lowe; Rodger P McEver; Arun Srivastava; Rita Sarkar
Working group report: the roles of glycans in hemostasis, inflammation and vascular biology.
Glycobiology 2008;18(10):747-9.
2008: Lan Zhou; Lebing Wei Li; Quanjian Yan; Bronislawa Petryniak; Yunfang Man; Charles Su; Jeongsup Shim; Stephanie Chervin; John B Lowe
Notch-dependent control of myelopoiesis is regulated by fucosylation.
Blood 2008;112(2):308-19.
2007: Matthew A Schaller; Rupak Neupane; Brian D Rudd; Steven Kunkel; Lara E Kallal; Pamela M Lincoln; John B Lowe; Yunfang Man; Nicholas W Lukacs
Notch ligand Delta-like 4 regulates disease pathogenesis during respiratory viral infections by modulating Th2 cytokines.
The Journal of experimental medicine 2007;204(12):2925-34.
2007: Junya Mitoma; Xingfeng Bao; Bronislawa Petryanik; Patrick Schaerli; Jean-Marc Gauguet; Shin-Yi Yu; Hiroto Kawashima; Hideo Saito; Kazuaki Ohtsubo; Jamey D Marth; Kay-Hooi Khoo; Ulrich H von Andrian; John B Lowe; Minoru Fukuda
Critical functions of N-glycans in L-selectin-mediated lymphocyte homing and recruitment.
Nature immunology 2007;8(4):409-18.
2007: Nobuyoshi Hiraoka; Bronislawa Petryniak; Hiroto Kawashima; Junya Mitoma; Tomoya O Akama; Michiko N Fukuda; John B Lowe; Minoru Fukuda
Significant decrease in alpha1,3-linked fucose in association with increase in 6-sulfated N-acetylglucosamine in peripheral lymph node addressin of FucT-VII-deficient mice exhibiting diminished lymphocyte homing.
Glycobiology 2007;17(3):277-93.
2005: Shihao Chen; Hiroto Kawashima; John B Lowe; Lewis L Lanier; Minoru Fukuda
Suppression of tumor formation in lymph nodes by L-selectin-mediated natural killer cell recruitment.
The Journal of experimental medicine 2005;202(12):1679-89.
2005: Hiroto Kawashima; Bronislawa Petryniak; Nobuyoshi Hiraoka; Junya Mitoma; Valerie Huckaby; Jun Nakayama; Kenji Uchimura; Kenji Kadomatsu; Takashi Muramatsu; John B Lowe; Minoru Fukuda
N-acetylglucosamine-6-O-sulfotransferases 1 and 2 cooperatively control lymphocyte homing through L-selectin ligand biosynthesis in high endothelial venules.
Nature immunology 2005;6(11):1096-104.
2005: Laura Piccio; Barbara Rossi; Lucia Colantonio; Roland Grenningloh; Andrea Gho; Linda Ottoboni; Jonathon W Homeister; Elio Scarpini; Marianna Martinello; Carlo Laudanna; Daniele D'Ambrosio; John B Lowe; Gabriela Constantin
Efficient recruitment of lymphocytes in inflamed brain venules requires expression of cutaneous lymphocyte antigen and fucosyltransferase-VII.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(9):5805-13.
2005: John B Lowe
Cell biology. Does Notch take the sweet road to success?
Science (New York, N.Y.) 2005;307(5715):1570-2.
2005: John B Lowe
Fucosylated glycans in innate and adaptive immmunity.
Advances in experimental medicine and biology 2005;564():127-8.
2004: Jonathon W Homeister; Alan Daugherty; John B Lowe
Alpha(1,3)fucosyltransferases FucT-IV and FucT-VII control susceptibility to atherosclerosis in apolipoprotein E-/- mice.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(10):1897-903.
2004: Nobuyoshi Hiraoka; Hiroto Kawashima; Bronislawa Petryniak; Jun Nakayama; Junya Mitoma; Jamey D Marth; John B Lowe; Minoru Fukuda
Core 2 branching beta1,6-N-acetylglucosaminyltransferase and high endothelial venule-restricted sulfotransferase collaboratively control lymphocyte homing.
The Journal of biological chemistry 2004;279(4):3058-67.
2003: John B Lowe
Glycan-dependent leukocyte adhesion and recruitment in inflammation.
Current opinion in cell biology 2003;15(5):531-8.
2003: Daniel J Becker; John B Lowe
Fucose: biosynthesis and biological function in mammals.
Glycobiology 2003;13(7):41R-53R.
2003: Junya Mitoma; Bronislawa Petryniak; Nobuyoshi Hiraoka; Jiunn-Chern Yeh; John B Lowe; Minoru Fukuda
Extended core 1 and core 2 branched O-glycans differentially modulate sialyl Lewis X-type L-selectin ligand activity.
The Journal of biological chemistry 2003;278(11):9953-61.
2003: Daniel J Becker; Jesse T Myers; Melissa M Ruff; Peter L Smith; Brenda W Gillespie; David Ginsburg; John B Lowe
Strain-specific modification of lethality in fucose-deficient mice.
Mammalian genome : official journal of the International Mammalian Genome Society 2003;14(2):130-9.
2003: John B Lowe; Jamey D Marth
A genetic approach to Mammalian glycan function.
Annual review of biochemistry 2003;72():643-91.
2002: Kristina A Thomsson; Marina Hinojosa-Kurtzberg; Karin A Axelsson; Steven E Domino; John B Lowe; Sandra J Gendler; Gunnar Hansson
Intestinal mucins from cystic fibrosis mice show increased fucosylation due to an induced Fucalpha1-2 glycosyltransferase.
The Biochemical journal 2002;367(Pt 3):609-16.
2002: Peter L Smith; Jesse T Myers; Clare E Rogers; Lan Zhou; Bronislawa Petryniak; Daniel J Becker; Jonathon W Homeister; John B Lowe
Conditional control of selectin ligand expression and global fucosylation events in mice with a targeted mutation at the FX locus.
The Journal of cell biology 2002;158(4):801-15.
2002: Stephanie M Chervin; John B Lowe; Masato Koreeda
Synthesis and biological evaluation of a new sialyl Lewis X mimetic derived from lactose.
The Journal of organic chemistry 2002;67(16):5654-62.
2002: John B Lowe
Glycosylation in the control of selectin counter-receptor structure and function.
Immunological reviews 2002;186():19-36.
2002: Irina B Mazo; Elizabeth J Quackenbush; John B Lowe; Ulrich H von Andrian
Total body irradiation causes profound changes in endothelial traffic molecules for hematopoietic progenitor cell recruitment to bone marrow.
Blood 2002;99(11):4182-91.
2002: John B Lowe
Glycosyltransferases and glycan structures contributing to the adhesive activities of L-, E- and P-selectin counter-receptors.
Biochemical Society symposium 2002;(69):33-45.
2001: Steven E Domino; Lizhi Zhang; P J Gillespie; Thomas L Saunders; John B Lowe
Deficiency of reproductive tract alpha(1,2)fucosylated glycans and normal fertility in mice with targeted deletions of the FUT1 or FUT2 alpha(1,2)fucosyltransferase locus.
Molecular and cellular biology 2001;21(24):8336-45.
2001: GM Smithson; Clare E Rogers; Peter L Smith; E P Scheidegger; Bronislawa Petryniak; Jesse T Myers; D S Kim; Jonathon W Homeister; John B Lowe
Fuc-TVII is required for T helper 1 and T cytotoxic 1 lymphocyte selectin ligand expression and recruitment in inflammation, and together with Fuc-TIV regulates naive T cell trafficking to lymph nodes.
The Journal of experimental medicine 2001;194(5):601-14.
2001: Jonathon W Homeister; A D Thall; Bronislawa Petryniak; P Malý; Clare E Rogers; Peter L Smith; Reagan J Kelly; K M Gersten; S W Askari; G Cheng; GM Smithson; Rory M Marks; A K Misra; Ole Hindsgaul; Ulrich H von Andrian; John B Lowe
The alpha(1,3)fucosyltransferases FucT-IV and FucT-VII exert collaborative control over selectin-dependent leukocyte recruitment and lymphocyte homing.
Immunity 2001;15(1):115-26.
2001: Jiunn-Chern Yeh; Nobuyoshi Hiraoka; Bronislawa Petryniak; Jun Nakayama; Lesley G Ellies; David Rabuka; Ole Hindsgaul; Jamey D Marth; John B Lowe; Michiko N Fukuda
Novel sulfated lymphocyte homing receptors and their control by a Core1 extension beta 1,3-N-acetylglucosaminyltransferase.
Cell 2001;105(7):957-69.
2001: Steven E Domino; Lizhi Zhang; John B Lowe
Molecular cloning, genomic mapping, and expression of two secretor blood group alpha (1,2)fucosyltransferase genes differentially regulated in mouse uterine epithelium and gastrointestinal tract.
The Journal of biological chemistry 2001;276(26):23748-56.
2001: John B Lowe
Glycosylation, immunity, and autoimmunity.
Cell 2001;104(6):809-12.
1999: Daniel J Becker; John B Lowe
Leukocyte adhesion deficiency type II.
Biochimica et biophysica acta 1999;1455(2-3):193-204.
1999: Nobuyoshi Hiraoka; Bronislawa Petryniak; Jun Nakayama; Shigeru Tsuboi; Misa Suzuki; Jiunn-Chern Yeh; D Izawa; T Tanaka; M Miyasaka; John B Lowe; Michiko N Fukuda
A novel, high endothelial venule-specific sulfotransferase expresses 6-sulfo sialyl Lewis(x), an L-selectin ligand displayed by CD34.
Immunity 1999;11(1):79-89.
1999: Karen L Mohlke; AA Purkayastha; Randal J Westrick; Peter L Smith; Bronislawa Petryniak; John B Lowe; David Ginsburg
Mvwf, a dominant modifier of murine von Willebrand factor, results from altered lineage-specific expression of a glycosyltransferase.
Cell 1999;96(1):111-20.
1998: Lesley G Ellies; Shigeru Tsuboi; Bronislawa Petryniak; John B Lowe; Michiko N Fukuda; Jamey D Marth
Core 2 oligosaccharide biosynthesis distinguishes between selectin ligands essential for leukocyte homing and inflammation.
Immunity 1998;9(6):881-90.
1998: Randall N Knibbs; Ronald A Craig; P Mály; Peter L Smith; FM Wolber; Neil E Faulkner; John B Lowe; Lloyd M Stoolman
Alpha(1,3)-fucosyltransferase VII-dependent synthesis of P- and E-selectin ligands on cultured T lymphoblasts.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(11):6305-15.
1998: FM Wolber; Jeffrey L Curtis; P Mály; Reagan J Kelly; P Smith; T A Yednock; John B Lowe; Lloyd M Stoolman
Endothelial selectins and alpha4 integrins regulate independent pathways of T lymphocyte recruitment in the pulmonary immune response.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(8):4396-403.
1998: Jonathon W Homeister; M Zhang; Paul S. Frenette; R O Hynes; Denisa D Wagner; John B Lowe; Rory M Marks
Overlapping functions of E- and P-selectin in neutrophil recruitment during acute inflammation.
Blood 1998;92(7):2345-52.
1998: C Ohyama; P L Smith; Kiyohiko Angata; M N Fukuda; John B Lowe; Michiko N Fukuda
Molecular cloning and expression of GDP-D-mannose-4,6-dehydratase, a key enzyme for fucose metabolism defective in Lec13 cells.
The Journal of biological chemistry 1998;273(23):14582-7.
1998: Michael S Mulligan; Roscoe L Warner; John B Lowe; Peter L Smith; Y Suzuki; M Miyasaka; S Yamaguchi; Y Ohta; Y Tsukada; M Kiso; A Hasegawa; Peter A Ward
In vitro and in vivo selectin-blocking activities of sulfated lipids and sulfated sialyl compounds.
International immunology 1998;10(5):569-75.
1997: John B Lowe; Peter A Ward
Therapeutic inhibition of carbohydrate-protein interactions in vivo.
The Journal of clinical investigation 1997;100(11 Suppl):S47-51.
1997: Steven E Domino; N Hiraiwa; John B Lowe
Molecular cloning, chromosomal assignment and tissue-specific expression of a murine alpha(1,2)fucosyltransferase expressed in thymic and epididymal epithelial cells.
The Biochemical journal 1997;327 ( Pt 1)():105-15.
1997: John B Lowe
Selectin ligands, leukocyte trafficking, and fucosyltransferase genes.
Kidney international 1997;51(5):1418-26.
1997: John B Lowe; Peter A Ward
Therapeutic inhibition of carbohydrate-protein interactions in vivo.
The Journal of clinical investigation 1997;99(5):822-6.
1996: Kelvin P Lee; L M Carlson; J B Woodcock; N Ramachandra; T L Schultz; T A Davis; John B Lowe; Craig Thompson; R D Larsen
Molecular cloning and characterization of CFT1, a developmentally regulated avian alpha(1,3)-fucosyltransferase gene.
The Journal of biological chemistry 1996;271(51):32960-7.
1996: P Malý; A Thall; B Petryniak; C E Rogers; Peter L Smith; Rory M Marks; R J Kelly; K M Gersten; G Cheng; Thomas L Saunders; Sally A Camper; Raymond T Camphausen; F X Sullivan; Y Isogai; O Hindsgaul; U H von Andrian; John B Lowe
The alpha(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis.
Cell 1996;86(4):643-53.
1996: Randall N Knibbs; R A Craig; S Natsuka; Alfred E Chang; Mark Cameron; John B Lowe; Lloyd M Stoolman
The fucosyltransferase FucT-VII regulates E-selectin ligand synthesis in human T cells.
The Journal of cell biology 1996;133(4):911-20.
1996: Peter L Smith; K M Gersten; B Petryniak; R J Kelly; C Rogers; Y Natsuka; J A Alford; E P Scheidegger; S Natsuka; John B Lowe
Expression of the alpha(1,3)fucosyltransferase Fuc-TVII in lymphoid aggregate high endothelial venules correlates with expression of L-selectin ligands.
The Journal of biological chemistry 1996;271(14):8250-9.
1996: A D Thall; Hedwig S Murphy; John B Lowe
alpha 1,3-Galactosyltransferase-deficient mice produce naturally occurring cytotoxic anti-Gal antibodies.
Transplantation proceedings 1996;28(2):556-7.
1995: K M Gersten; S Natsuka; M Trinchera; B Petryniak; R J Kelly; N Hiraiwa; N A Jenkins; D J Gilbert; N G Copeland; John B Lowe
Molecular cloning, expression, chromosomal assignment, and tissue-specific expression of a murine alpha-(1,3)-fucosyltransferase locus corresponding to the human ELAM-1 ligand fucosyl transferase.
The Journal of biological chemistry 1995;270(42):25047-56.
1995: E P Scheidegger; L R Sternberg; Jürgen Roth; John B Lowe
A human STX cDNA confers polysialic acid expression in mammalian cells.
The Journal of biological chemistry 1995;270(39):22685-8.
1995: A D Thall; P Malý; John B Lowe
Oocyte Gal alpha 1,3Gal epitopes implicated in sperm adhesion to the zona pellucida glycoprotein ZP3 are not required for fertilization in the mouse.
The Journal of biological chemistry 1995;270(37):21437-40.
1995: D J Legault; R J Kelly; Y Natsuka; John B Lowe
Human alpha(1,3/1,4)-fucosyltransferases discriminate between different oligosaccharide acceptor substrates through a discrete peptide fragment.
The Journal of biological chemistry 1995;270(36):20987-96.
1995: R J Kelly; Sylvie Rouquier; Dominique Giorgi; GG Lennon; John B Lowe
Sequence and expression of a candidate for the human Secretor blood group alpha(1,2)fucosyltransferase gene (FUT2). Homozygosity for an enzyme-inactivating nonsense mutation commonly correlates with the non-secretor phenotype.
The Journal of biological chemistry 1995;270(9):4640-9.
1995: Sylvie Rouquier; John B Lowe; R J Kelly; A L Fertitta; GG Lennon; Dominique Giorgi
Molecular cloning of a human genomic region containing the H blood group alpha(1,2)fucosyltransferase gene and two H locus-related DNA restriction fragments. Isolation of a candidate for the human Secretor blood group locus.
The Journal of biological chemistry 1995;270(9):4632-9.
1995: I Reguigne-Arnould; P Couillin; Rosella Mollicone; S Fauré; A Fletcher; R J Kelly; John B Lowe; Rafael Oriol
Relative positions of two clusters of human alpha-L-fucosyltransferases in 19q (FUT1-FUT2) and 19p (FUT6-FUT3-FUT5) within the microsatellite genetic map of chromosome 19.
Cytogenetics and cell genetics 1995;71(2):158-62.
1994: S Sueyoshi; Shigeru Tsuboi; R Sawada-Hirai; U N Dang; John B Lowe; Michiko N Fukuda
Expression of distinct fucosylated oligosaccharides and carbohydrate-mediated adhesion efficiency directed by two different alpha-1,3-fucosyltransferases. Comparison of E- and L-selectin-mediated adhesion.
The Journal of biological chemistry 1994;269(51):32342-50.
1994: Rosella Mollicone; I Reguigne; R J Kelly; A Fletcher; J Watt; S Chatfield; A Aziz; H S Cameron; Brent W Weston; John B Lowe
Molecular basis for Lewis alpha(1,3/1,4)-fucosyltransferase gene deficiency (FUT3) found in Lewis-negative Indonesian pedigrees.
The Journal of biological chemistry 1994;269(33):20987-94.
1994: S Natsuka; K M Gersten; K Zenita; R Kannagi; John B Lowe
Molecular cloning of a cDNA encoding a novel human leukocyte alpha-1,3-fucosyltransferase capable of synthesizing the sialyl Lewis x determinant.
The Journal of biological chemistry 1994;269(32):20806.
1994: R J Kelly; L K Ernst; R D Larsen; J G Bryant; J S Robinson; John B Lowe
Molecular basis for H blood group deficiency in Bombay (Oh) and para-Bombay individuals.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(13):5843-7.
1994: S Natsuka; K M Gersten; K Zenita; R Kannagi; John B Lowe
Molecular cloning of a cDNA encoding a novel human leukocyte alpha-1,3-fucosyltransferase capable of synthesizing the sialyl Lewis x determinant.
The Journal of biological chemistry 1994;269(24):16789-94.
1994: Peter L Smith; John B Lowe
Molecular cloning of a murine N-acetylgalactosamine transferase cDNA that determines expression of the T lymphocyte-specific CT oligosaccharide differentiation antigen.
The Journal of biological chemistry 1994;269(21):15162-71.
1994: Rosella Mollicone; I Reguigne; A Fletcher; A Aziz; M Rustam; Brent W Weston; R J Kelly; John B Lowe; Rafael Oriol
Molecular basis for plasma alpha(1,3)-fucosyltransferase gene deficiency (FUT6).
The Journal of biological chemistry 1994;269(17):12662-71.
1994: I Reguigne; M R James; C W Richard; Rosella Mollicone; A Seawright; John B Lowe; Rafael Oriol; P Couillin
The gene encoding myeloid alpha-3-fucosyl-transferase (FUT4) is located between D1 1S388 and D11S919 on 11q21.
Cytogenetics and cell genetics 1994;66(2):104-6.
1993: Michael S Mulligan; John B Lowe; R D Larsen; J Paulson; Z L Zheng; S DeFrees; K Maemura; M Fukuda; Peter A Ward
Protective effects of sialylated oligosaccharides in immune complex-induced acute lung injury.
The Journal of experimental medicine 1993;178(2):623-31.
1993: Michael S Mulligan; J C Paulson; S De Frees; Z L Zheng; John B Lowe; Peter A Ward
Protective effects of oligosaccharides in P-selectin-dependent lung injury.
Nature 1993;364(6433):149-51.
1993: John B Lowe
The blood group-specific human glycosyltransferases.
Baillière's clinical haematology 1993;6(2):465-92.
1992: Brent W Weston; Peter L Smith; R J Kelly; John B Lowe
Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes.
The Journal of biological chemistry 1992;267(34):24575-84.
1992: Brent W Weston; Rajan P Nair; R D Larsen; John B Lowe
Isolation of a novel human alpha (1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities.
The Journal of biological chemistry 1992;267(6):4152-60.
1991: John B Lowe
Molecular cloning, expression, and uses of mammalian glycosyltransferases.
Seminars in cell biology 1991;2(5):289-307.
1991: John B Lowe; Jolanta F Kukowska-Latallo; Rajan P Nair; R D Larsen; Rory M Marks; Bruce A Macher; R J Kelly; L K Ernst
Molecular cloning of a human fucosyltransferase gene that determines expression of the Lewis x and VIM-2 epitopes but not ELAM-1-dependent cell adhesion.
The Journal of biological chemistry 1991;266(26):17467-77.
1991: John B Lowe; Lloyd M Stoolman; Rajan P Nair; R D Larsen; T L Behrend; Rory M Marks
A transfected human fucosyltransferase cDNA determines biosynthesis of oligosaccharide ligand(s) for endothelial-leukocyte adhesion molecule I.
Biochemical Society transactions 1991;19(3):649-53.
1990: John B Lowe; Lloyd M Stoolman; Rajan P Nair; R D Larsen; T L Berhend; Rory M Marks
ELAM-1--dependent cell adhesion to vascular endothelium determined by a transfected human fucosyltransferase cDNA.
Cell 1990;63(3):475-84.
1990: R D Larsen; L K Ernst; Rajan P Nair; John B Lowe
Molecular cloning, sequence, and expression of a human GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase cDNA that can form the H blood group antigen.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(17):6674-8.
1990: Jolanta F Kukowska-Latallo; R D Larsen; Rajan P Nair; John B Lowe
A cloned human cDNA determines expression of a mouse stage-specific embryonic antigen and the Lewis blood group alpha(1,3/1,4)fucosyltransferase.
Genes & development 1990;4(8):1288-303.
1990: R D Larsen; C A Rivera-Marrero; L K Ernst; Richard D Cummings; John B Lowe
Frameshift and nonsense mutations in a human genomic sequence homologous to a murine UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha(1,3)-galactosyltransferase cDNA.
The Journal of biological chemistry 1990;265(12):7055-61.
1989: R D Larsen; V P Rajan; M M Ruff; Jolanta F Kukowska-Latallo; Richard D Cummings; John B Lowe
Isolation of a cDNA encoding a murine UDPgalactose:beta-D-galactosyl- 1,4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase: expression cloning by gene transfer.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(21):8227-31.
1989: V P Rajan; R D Larsen; S Ajmera; L K Ernst; John B Lowe
A cloned human DNA restriction fragment determines expression of a GDP-L-fucose: beta-D-galactoside 2-alpha-L-fucosyltransferase in transfected cells. Evidence for isolation and transfer of the human H blood group locus.
The Journal of biological chemistry 1989;264(19):11158-67.
1989: R Yabkowitz; John B Lowe; Xiaodong Huang
Expression and initial characterization of a recombinant human thrombospondin heparin binding domain.
The Journal of biological chemistry 1989;264(18):10888-96.
1989: L K Ernst; V P Rajan; R D Larsen; M M Ruff; John B Lowe
Stable expression of blood group H determinants and GDP-L-fucose: beta-D-galactoside 2-alpha-L-fucosyltransferase in mouse cells after transfection with human DNA.
The Journal of biological chemistry 1989;264(6):3436-47.