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Aigang Lu

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Yalikun Suofu; Kenneth R Wagner; J P Broderick; J F Clark; Y Kurosawa; Aigang Lu
Matrix metalloproteinase-2 or -9 deletions protect against hemorrhagic transformation during early stage of cerebral ischemia and reperfusion.
Yalian Sa; Jinsong Hao; Divya Samineni; Joseph Clark; Gail Pyne-Geithman; Joseph Broderick; Aigang Lu
Brain distribution and elimination of recombinant human TIMP-1 after cerebral ischemia and reperfusion in rats.
Huichun Xu; Aigang Lu; Frank R Sharp
Regional genome transcriptional response of adult mouse brain to hypoxia.

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All Publications

2012: Yalikun Suofu; Kenneth R Wagner; J P Broderick; J F Clark; Y Kurosawa; Aigang Lu
Matrix metalloproteinase-2 or -9 deletions protect against hemorrhagic transformation during early stage of cerebral ischemia and reperfusion.
Neuroscience 2012;212():180-9.
2011: Yalian Sa; Jinsong Hao; Divya Samineni; Joseph Clark; Gail Pyne-Geithman; Joseph Broderick; Aigang Lu
Brain distribution and elimination of recombinant human TIMP-1 after cerebral ischemia and reperfusion in rats.
Neurological research 2011;33(4):433-8.
2011: Huichun Xu; Aigang Lu; Frank R Sharp
Regional genome transcriptional response of adult mouse brain to hypoxia.
BMC genomics 2011;12():499.
2011: Joseph F Clark; Amanda Harm; Ashlie Saffire; Susan J Biehle; Aigang Lu; Gail J Pyne-Geithman
Bilirubin oxidation products seen post subarachnoid hemorrhage have greater effects on aged rat brain compared to young.
Acta neurochirurgica. Supplement 2011;110(Pt 1):157-62.
2010: Yalikun Suofu; Joseph Clark; Joseph Broderick; Kenneth R Wagner; Thomas Tomsick; ya_lian sa; Aigang Lu
Peroxynitrite decomposition catalyst prevents matrix metalloproteinase activation and neurovascular injury after prolonged cerebral ischemia in rats.
Journal of neurochemistry 2010;115(5):1266-76.
2010: Yuko Kurosawa; Aigang Lu; Pooja Khatri; Janice Carrozzella; Joseph F Clark; Jane Khoury; Thomas A Tomsick
Intra-arterial iodinated radiographic contrast material injection administration in a rat middle cerebral artery occlusion and reperfusion model: possible effects on intracerebral hemorrhage.
Stroke; a journal of cerebral circulation 2010;41(5):1013-7.
2009: Aigang Lu; Joseph F Clark; Ruiqiong Ran; Gail Pyne-Geithman; Kenneth R Wagner; David E Millhorn; Frank R Sharp
Down-regulation of interleukin 7 mRNA by hypoxia is calcium dependent.
Neurological research 2009;31(5):545-9.
2009: Aigang Lu; Joseph F Clark; Joseph P Broderick; Gail J Pyne-Geithman; Kenneth R Wagner; Pooja Khatri; Thomas A Tomsick; Frank R Sharp
Mechanical reperfusion is associated with post-ischemic hemorrhage in rat brain.
Experimental neurology 2009;216(2):407-12.
2009: Aigang Lu; Yuko Kurosawa; Kenneth Luskey; Gail Pyne-Geithman; Danielle Caudell; Joseph Clark
Hemorrhagic profile of the fibrinolytic alfimeprase after ischemia and reperfusion.
Neurological research 2009;31(2):209-14.
2009: Matthew C Loftspring; Jeremiah McDole; Aigang Lu; Joseph F Clark; Aaron J Johnson
Intracerebral hemorrhage leads to infiltration of several leukocyte populations with concomitant pathophysiological changes.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(1):137-43.
2008: Aigang Lu; Joseph F Clark; Joseph P Broderick; Gail J Pyne-Geithman; Kenneth R Wagner; Ruiqiong Ran; Pooja Khatri; Thomas A Tomsick; Frank R Sharp
Reperfusion activates metalloproteinases that contribute to neurovascular injury.
Experimental neurology 2008;210(2):549-59.
2007: Ruiqiong Ran; Ruiqin Pan; Aigang Lu; Huichun Xu; Ryan R Davis; Frank R Sharp
A novel 165-kDa Golgin protein induced by brain ischemia and phosphorylated by Akt protects against apoptosis.
Molecular and cellular neurosciences 2007;36(3):392-407.
2006: Yang Tang; Huichun Xu; XinLi Du; Lisa Lit; Wynn Walker; Aigang Lu; Ruiqiong Ran; Jeffrey P Gregg; Melinda Reilly; Art Pancioli; Jane C Khoury; Laura Sauerbeck; Janice Carrozzella; Judith Spilker; Joseph Clark; Kenneth R Wagner; Edward Jauch; Dongwoo J Chang; Piero Verro; Joseph P Broderick; Frank R Sharp
Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: a microarray study.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(8):1089-102.
2006: Aigang Lu; Yang Tang; Ruiqiong Ran; Timothy L Ardizzone; Kenneth R Wagner; Frank R Sharp
Brain genomics of intracerebral hemorrhage.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(2):230-52.
2006: Joseph F Clark; Amos Doepke; Jessica Andrea Filosa; Robert L Wardle; Aigang Lu; Timothy J Meeker; Gail J Pyne-Geithman
N-acetylaspartate as a reservoir for glutamate.
Medical hypotheses 2006;67(3):506-12.
2005: Ruiqiong Ran; Huichun Xu; Aigang Lu; Myriam Bernaudin; Frank R Sharp
Hypoxia preconditioning in the brain.
Developmental neuroscience 2005;27(2-4):87-92.
2004: Yang Tang; Aigang Lu; Ruiqiong Ran; Bruce Aronow; Elizabeth K Schorry; Robert J Hopkin; Donald L Gilbert; Tracy A Glauser; Andrew D Hershey; Neil W Richtand; Michael D Privitera; Arif Dalvi; Alok Sahay; Jerzy P Szaflarski; David M Ficker; Nancy Ratner; Frank R Sharp
Human blood genomics: distinct profiles for gender, age and neurofibromatosis type 1.
Brain research. Molecular brain research 2004;132(2):155-67.
2004: Chia-Yi Kuan; Aryn Schloemer; Aigang Lu; Kevin A Burns; Wei-Lan Weng; Michael T Williams; Kenneth I Strauss; Charles V Vorhees; Richard A Flavell; Roger J Davis; Frank R Sharp; Pasko Rakic
Hypoxia-ischemia induces DNA synthesis without cell proliferation in dying neurons in adult rodent brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(47):10763-72.
2004: Timothy D Ardizzone; Aigang Lu; Kenneth R Wagner; Yang Tang; Ruiqiong Ran; Frank R Sharp
Glutamate receptor blockade attenuates glucose hypermetabolism in perihematomal brain after experimental intracerebral hemorrhage in rat.
Stroke; a journal of cerebral circulation 2004;35(11):2587-91.
2004: Ruiqiong Ran; Aigang Lu; Lu Zhang; Yang Tang; Hongyan Zhu; Huichun Xu; Yuxin Feng; Chun Han; Guoping Zhou; Alan Rigby; Frank R Sharp
Hsp70 promotes TNF-mediated apoptosis by binding IKK gamma and impairing NF-kappa B survival signaling.
Genes & development 2004;18(12):1466-81.
2004: Juha-Pekka Kalkkila; Frank R Sharp; Iivari Kärkkäinen; Melinda Reilly; Aigang Lu; Karen Solway; Matt Murrel; Jari Honkaniemi
Cloning and expression of short interspersed elements B1 and B2 in ischemic brain.
The European journal of neuroscience 2004;19(5):1199-206.
2004: Frank R Sharp; Ruiqiong Ran; Aigang Lu; Yang Tang; Kenneth I Strauss; Todd Glass; Timothy D Ardizzone; Myriam Bernaudin
Hypoxic preconditioning protects against ischemic brain injury.
NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 2004;1(1):26-35.
2004: Ruiqiong Ran; Guoping Zhou; Aigang Lu; Lu Zhang; Yang Tang; Alan Rigby; Frank R Sharp
Hsp70 mutant proteins modulate additional apoptotic pathways and improve cell survival.
Cell stress & chaperones 2004;9(3):229-42.
2003: Aigang Lu; Yang Tang; Ruiqiong Ran; Joseph F Clark; Bruce Aronow; Frank R Sharp
Genomics of the periinfarction cortex after focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(7):786-810.
2003: Kenneth R Wagner; Frank R Sharp; Timothy D Ardizzone; Aigang Lu; Joseph F Clark
Heme and iron metabolism: role in cerebral hemorrhage.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(6):629-52.
2003: Yang Tang; Alex Nee; Aigang Lu; Ruiqiong Ran; Frank R Sharp
Blood genomic expression profile for neuronal injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(3):310-9.
2002: Guodong Cao; Wei Pei; Hailiang Ge; Qinhua Liang; Yumin Luo; Frank R Sharp; Aigang Lu; Ruiqiong Ran; Steven H Graham; Jun Chen
In Vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(13):5423-31.
2002: Yang Tang; Aigang Lu; Bruce Aronow; Kenneth R Wagner; Frank R Sharp
Genomic responses of the brain to ischemic stroke, intracerebral haemorrhage, kainate seizures, hypoglycemia, and hypoxia.
The European journal of neuroscience 2002;15(12):1937-52.
2002: Aigang Lu; Ruiqiong Ran; Sophie Parmentier-Batteur; Alex Nee; Frank R Sharp
Geldanamycin induces heat shock proteins in brain and protects against focal cerebral ischemia.
Journal of neurochemistry 2002;81(2):355-64.
2002: Patricia Murphy; Anthony Sharp; Joseph Shin; Vitaliy Gavrilyuk; Cinzia Dello Russo; Guy Weinberg; Frank R Sharp; Aigang Lu; Michael T Heneka; Douglas L Feinstein
Suppressive effects of ansamycins on inducible nitric oxide synthase expression and the development of experimental autoimmune encephalomyelitis.
Journal of neuroscience research 2002;67(4):461-70.
2002: Aigang Lu; Ruiqiong Ran; Joseph Clark; Melinda Reilly; Alex Nee; Frank R Sharp
17-beta-estradiol induces heat shock proteins in brain arteries and potentiates ischemic heat shock protein induction in glia and neurons.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(2):183-95.
2001: Yang Tang; Aigang Lu; Bruce Aronow; Frank R Sharp
Blood genomic responses differ after stroke, seizures, hypoglycemia, and hypoxia: blood genomic fingerprints of disease.
Annals of neurology 2001;50(6):699-707.
2000: Frank R Sharp; Aigang Lu; Yang Tang; David E Millhorn
Multiple molecular penumbras after focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(7):1011-32.