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Dunyue Lu

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Jiahang Sun; Chuncheng Xie; Qi Huang; Zhihui Huo; Wei Liu; Dunyue Lu; Weidong Qiao; Hong Shen; Zhiguo Lin
The effects of simvastatin on hippocampal caspase-3 and Bcl-2 expression following kainate-induced seizures in rats.
Hongtao Wu; Ye Xiong; Dong Zhou; Changsheng Qu; Michael Chopp; Hao Jiang; Dunyue Lu; Asim Mahmood
Induction of angiogenesis and modulation of vascular endothelial growth factor receptor-2 by simvastatin after traumatic brain injury.
Chuncheng Xie; Xiaohua Hou; Dunyue Lu; Meng Na; Weidong Qiao; Yuanyuan Song; Jiahang Sun; Lanlan Wei; Zhiguo Lin
Administration of simvastatin after kainic acid-induced status epilepticus restrains chronic temporal lobe epilepsy.

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All Publications

2012: Jiahang Sun; Chuncheng Xie; Qi Huang; Zhihui Huo; Wei Liu; Dunyue Lu; Weidong Qiao; Hong Shen; Zhiguo Lin
The effects of simvastatin on hippocampal caspase-3 and Bcl-2 expression following kainate-induced seizures in rats.
International journal of molecular medicine 2012;30(4):739-46.
2011: Hongtao Wu; Ye Xiong; Dong Zhou; Changsheng Qu; Michael Chopp; Hao Jiang; Dunyue Lu; Asim Mahmood
Induction of angiogenesis and modulation of vascular endothelial growth factor receptor-2 by simvastatin after traumatic brain injury.
Neurosurgery 2011;68(5):1363-71; discussion 1371.
2011: Chuncheng Xie; Xiaohua Hou; Dunyue Lu; Meng Na; Weidong Qiao; Yuanyuan Song; Jiahang Sun; Lanlan Wei; Zhiguo Lin
Administration of simvastatin after kainic acid-induced status epilepticus restrains chronic temporal lobe epilepsy.
PloS one 2011;6(9):e24966.
2011: Tarique Perera; Leonard A Rosenblum; Eric L P Smith; Lakshmi Thirumangalakudi; Arkadiy Yaretskiy; John G Kral; Dunyue Lu; Jeremy D Coplan
Correlations between hippocampal neurogenesis and metabolic indices in adult nonhuman primates.
Neural plasticity 2011;2011():1-6.
2010: Hongtao Wu; Asim Mahmood; Dunyue Lu; Hao Jiang; Ye Xiong; Dong Zhou; Michael Chopp
Attenuation of astrogliosis and modulation of endothelial growth factor receptor in lipid rafts by simvastatin after traumatic brain injury.
Journal of neurosurgery 2010;113(3):591-7.
2009: Hongtao Wu; Hao Jiang; Dunyue Lu; Ye Xiong; Changsheng Qu; Dong Zhou; Asim Mahmood; Michael Chopp
Effect of simvastatin on glioma cell proliferation, migration, and apoptosis.
Neurosurgery 2009;65(6):1087-96; discussion 1096-7.
2009: Asim Mahmood; Anton Goussev; Humaira Kazmi; Changsheng Qu; Dunyue Lu; Michael Chopp
Long-term benefits after treatment of traumatic brain injury with simvastatin in rats.
Neurosurgery 2009;65(1):187-91; discussion 191-2.
2009: Bo Li; Asim Mahmood; Dunyue Lu; Hongtao Wu; Ye Xiong; Changsheng Qu; Michael Chopp
Simvastatin attenuates microglial cells and astrocyte activation and decreases interleukin-1beta level after traumatic brain injury.
Neurosurgery 2009;65(1):179-85; discussion 185-6.
2009: Michael Chopp; Asim Mahmood; Dunyue Lu; Yi Li
Editorial. Mesenchymal stem cell treatment of traumatic brain injury.
Journal of neurosurgery 2009;110(6):1186-8.
2008: Asim Mahmood; Anton Goussev; Dunyue Lu; Changsheng Qu; Ye Xiong; Humaira Kazmi; Michael Chopp
Long-lasting benefits after treatment of traumatic brain injury (TBI) in rats with combination therapy of marrow stromal cells (MSCs) and simvastatin.
Journal of neurotrauma 2008;25(12):1441-7.
2008: Hongtao Wu; Dunyue Lu; Hao Jiang; Ye Xiong; Changsheng Qu; Bo Li; Asim Mahmood; Dong Zhou; Michael Chopp
Increase in phosphorylation of Akt and its downstream signaling targets and suppression of apoptosis by simvastatin after traumatic brain injury.
Journal of neurosurgery 2008;109(4):691-8.
2008: Ye Xiong; Asim Mahmood; Dunyue Lu; Changsheng Qu; Humaira Kazmi; Anton Goussev; Zheng Gang Zhang; Constance T Noguchi; Timothy Schallert; Michael Chopp
Histological and functional outcomes after traumatic brain injury in mice null for the erythropoietin receptor in the central nervous system.
Brain research 2008;1230():247-57.
2008: Ye Xiong; Dunyue Lu; Changsheng Qu; Anton Goussev; Timothy Schallert; Asim Mahmood; Michael Chopp
Effects of erythropoietin on reducing brain damage and improving functional outcome after traumatic brain injury in mice.
Journal of neurosurgery 2008;109(3):510-21.
2008: Changsheng Qu; Asim Mahmood; Dunyue Lu; Anton Goussev; Ye Xiong; Michael Chopp
Treatment of traumatic brain injury in mice with marrow stromal cells.
Brain research 2008;1208():234-9.
2008: Hongtao Wu; Dunyue Lu; Hao Jiang; Ye Xiong; Changsheng Qu; Bo Li; Asim Mahmood; Dong Zhou; Michael Chopp
Simvastatin-mediated upregulation of VEGF and BDNF, activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury.
Journal of neurotrauma 2008;25(2):130-9.
2007: Ye Xiong; Asim Mahmood; Dunyue Lu; Changsheng Qu; Anton Goussev; Timothy Schallert; Michael Chopp
Role of gender in outcome after traumatic brain injury and therapeutic effect of erythropoietin in mice.
Brain research 2007;1185():301-12.
2007: Dunyue Lu; Asim Mahmood; Changsheng Qu; Xin Hong; David Kaplan; Michael Chopp
Collagen scaffolds populated with human marrow stromal cells reduce lesion volume and improve functional outcome after traumatic brain injury.
Neurosurgery 2007;61(3):596-602; discussion 602-3.
2007: Asim Mahmood; Dunyue Lu; Changsheng Qu; Anton Goussev; Zheng Gang Zhang; Chang Lu; Michael Chopp
Treatment of traumatic brain injury in rats with erythropoietin and carbamylated erythropoietin.
Journal of neurosurgery 2007;107(2):392-7.
2007: Dunyue Lu; Changsheng Qu; Anton Goussev; Hao Jiang; Chang Lu; Timothy Schallert; Asim Mahmood; Jieli Chen; Yi Li; Michael Chopp
Statins increase neurogenesis in the dentate gyrus, reduce delayed neuronal death in the hippocampal CA3 region, and improve spatial learning in rat after traumatic brain injury.
Journal of neurotrauma 2007;24(7):1132-46.
2007: Asim Mahmood; Dunyue Lu; Changsheng Qu; Anton Goussev; Michael Chopp
Treatment of traumatic brain injury with a combination therapy of marrow stromal cells and atorvastatin in rats.
Neurosurgery 2007;60(3):546-53; discussion 553-4.
2006: Yi Li; Kevin McIntosh; Jieli Chen; Chunling Zhang; Qi Gao; Jade Borneman; Kimberly Raginski; James Mitchell; Lihong Shen; Jing Zhang; Dunyue Lu; Michael Chopp
Allogeneic bone marrow stromal cells promote glial-axonal remodeling without immunologic sensitization after stroke in rats.
Experimental neurology 2006;198(2):313-25.
2006: Asim Mahmood; Dunyue Lu; Changsheng Qu; Anton Goussev; Michael Chopp
Long-term recovery after bone marrow stromal cell treatment of traumatic brain injury in rats.
Journal of neurosurgery 2006;104(2):272-7.
2005: Asim Mahmood; Dunyue Lu; Changsheng Qu; Anton Goussev; Michael Chopp
Human marrow stromal cell treatment provides long-lasting benefit after traumatic brain injury in rats.
Neurosurgery 2005;57(5):1026-31; discussion 1026-31.
2005: Changsheng Qu; Dunyue Lu; Anton Goussev; Timothy Schallert; Asim Mahmood; Michael Chopp
Effect of atorvastatin on spatial memory, neuronal survival, and vascular density in female rats after traumatic brain injury.
Journal of neurosurgery 2005;103(4):695-701.
2005: Dunyue Lu; Asim Mahmood; Changsheng Qu; Anton Goussev; Timothy Schallert; Michael Chopp
Erythropoietin enhances neurogenesis and restores spatial memory in rats after traumatic brain injury.
Journal of neurotrauma 2005;22(9):1011-7.
2005: Yi Li; Jieli Chen; Chun Ling Zhang; Lei Wang; Dunyue Lu; Mark Katakowski; Qi Gao; Li Hong Shen; Jing Zhang; Mei Lu; Michael Chopp
Gliosis and brain remodeling after treatment of stroke in rats with marrow stromal cells.
Glia 2005;49(3):407-17.
2004: Dunyue Lu; Asim Mahmood; Anton Goussev; Changsheng Qu; Zheng Gang Zhang; Michael Chopp
Delayed thrombosis after traumatic brain injury in rats.
Journal of neurotrauma 2004;21(12):1756-66.
2004: Dunyue Lu; Asim Mahmood; Changsheng Qu; Anton Goussev; Mei Lu; Michael Chopp
Atorvastatin reduction of intracranial hematoma volume in rats subjected to controlled cortical impact.
Journal of neurosurgery 2004;101(5):822-5.
2004: Dunyue Lu; Asim Mahmood; Anton Goussev; Timothy Schallert; Changsheng Qu; Zheng Gang Zhang; Yi Li; Mei Lu; Michael Chopp
Atorvastatin reduction of intravascular thrombosis, increase in cerebral microvascular patency and integrity, and enhancement of spatial learning in rats subjected to traumatic brain injury.
Journal of neurosurgery 2004;101(5):813-21.
2004: Asim Mahmood; Dunyue Lu; Michael Chopp
Marrow stromal cell transplantation after traumatic brain injury promotes cellular proliferation within the brain.
Neurosurgery 2004;55(5):1185-93.
2004: Donald Seyfried; Yuxia Han; Dunyue Lu; Jieli Chen; Ali Bydon; Michael Chopp
Improvement in neurological outcome after administration of atorvastatin following experimental intracerebral hemorrhage in rats.
Journal of neurosurgery 2004;101(1):104-7.
2004: Asim Mahmood; Dunyue Lu; Michael Chopp
Intravenous administration of marrow stromal cells (MSCs) increases the expression of growth factors in rat brain after traumatic brain injury.
Journal of neurotrauma 2004;21(1):33-9.
2004: Dunyue Lu; Anton Goussev; Jieli Chen; Paul Pannu; Yi Li; Asim Mahmood; Michael Chopp
Atorvastatin reduces neurological deficit and increases synaptogenesis, angiogenesis, and neuronal survival in rats subjected to traumatic brain injury.
Journal of neurotrauma 2004;21(1):21-32.
2003: Mei Lu; Jieli Chen; Dunyue Lu; Li Yi; Asim Mahmood; Michael Chopp
Global test statistics for treatment effect of stroke and traumatic brain injury in rats with administration of bone marrow stromal cells.
Journal of neuroscience methods 2003;128(1-2):183-90.
2003: Jieli Chen; Yi Li; Mark Katakowski; Xiaoguang Chen; Lei Wang; Dunyue Lu; Mei Lu; Subhash C Gautam; Michael Chopp
Intravenous bone marrow stromal cell therapy reduces apoptosis and promotes endogenous cell proliferation after stroke in female rat.
Journal of neuroscience research 2003;73(6):778-86.
2003: Asim Mahmood; Dunyue Lu; Mei Lu; Michael Chopp
Treatment of traumatic brain injury in adult rats with intravenous administration of human bone marrow stromal cells.
Neurosurgery 2003;53(3):697-702; discussion 702-3.
2003: Dunyue Lu; Asim Mahmood; Rui Lan Zhang; Michael Copp
Upregulation of neurogenesis and reduction in functional deficits following administration of DEtA/NONOate, a nitric oxide donor, after traumatic brain injury in rats.
Journal of neurosurgery 2003;99(2):351-61.
2003: Dunyue Lu; Asim Mahmood; Michael Chopp
Biologic transplantation and neurotrophin-induced neuroplasticity after traumatic brain injury.
The Journal of head trauma rehabilitation 2003;18(4):357-76.
2002: Asim Mahmood; Dunyue Lu; Lei Wang; Michael Chopp
Intracerebral transplantation of marrow stromal cells cultured with neurotrophic factors promotes functional recovery in adult rats subjected to traumatic brain injury.
Journal of neurotrauma 2002;19(12):1609-17.
2002: Dunyue Lu; Yi Li; Asim Mahmood; Lei Wang; Tahir Rafiq; Michael Chopp
Neural and marrow-derived stromal cell sphere transplantation in a rat model of traumatic brain injury.
Journal of neurosurgery 2002;97(4):935-40.
2002: Xiaoguang Chen; Mark Katakowski; Yi Li; Dunyue Lu; Lei Wang; Lijie Zhang; Jieli Chen; Yongxian Xu; Subhash C Gautam; Asim Mahmood; Michael Chopp
Human bone marrow stromal cell cultures conditioned by traumatic brain tissue extracts: growth factor production.
Journal of neuroscience research 2002;69(5):687-91.
2002: Dunyue Lu; Paul Sanberg; Asim Mahmood; Yi Li; Lei Wang; Juan Sanchez-Ramos; Michael Chopp
Intravenous administration of human umbilical cord blood reduces neurological deficit in the rat after traumatic brain injury.
Cell transplantation 2002;11(3):275-81.
2001: Asim Mahmood; Dunyue Lu; Lei Wang; Yi Li; Mei Lu; Michael Chopp
Treatment of traumatic brain injury in female rats with intravenous administration of bone marrow stromal cells.
Neurosurgery 2001;49(5):1196-203; discussion 1203-4.
2001: Dunyue Lu; Yi Li; Lei Wang; Jieli Chen; Asim Mahmood; Michael Chopp
Intraarterial administration of marrow stromal cells in a rat model of traumatic brain injury.
Journal of neurotrauma 2001;18(8):813-9.
2001: Asim Mahmood; Dunyue Lu; L Yi; Jieli Chen; Michael Chopp
Intracranial bone marrow transplantation after traumatic brain injury improving functional outcome in adult rats.
Journal of neurosurgery 2001;94(4):589-95.
1999: Zheng Gang Zhang; Michael Chopp; Anton Goussev; Dunyue Lu; Daniel Morris; Wayne Tsang; Cecylia Powers; Khang-Loon Ho
Cerebral microvascular obstruction by fibrin is associated with upregulation of PAI-1 acutely after onset of focal embolic ischemia in rats.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(24):10898-907.
1999: Zheng Gang Zhang; Michael Chopp; Dunyue Lu; T Wayne; Rui Lan Zhang; Daniel Morris
Receptor tyrosine kinase tie 1 mRNA is upregulated on cerebral microvessels after embolic middle cerebral artery occlusion in rat.
Brain research 1999;847(2):338-42.