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Yi Lu
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32
Liu, Juewen
8
Hwang, Hee Jung
8
Garner, Dewain
7
Berry, Steven
6
Li, Jing
6
Nilges, Mark
6
Pfister, Thomas
6
Wernette, Daryl
6
Zhao, Xuan
5
Wang, Xiaotang
5
Sigman, Jeffrey
5
Kim, Hee-Kyung
5
Brown, Andrea
5
Gengenbach, Alan
5
Cropek, Donald
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All Publications
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2009: Marshall Nicholas M; Garner Dewain K; Wilson Tiffany D; Gao Yi-Gui; Robinson Howard; Nilges Mark J; Lu Yi
Rationally tuning the reduction potential of a single cupredoxin beyond the natural range.
Nature 2009;462(7269):113-6.
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2009: Yigit Mehmet Veysel; Mishra Abhijit; Tong Rong; Cheng Jianjun; Wong Gerard C L; Lu Yi
Inorganic mercury detection and controlled release of chelating agents from ion-responsive liposomes.
Chemistry & biology 2009;16(9):937-42.
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2009: Lu Yi; Yeung Natasha; Sieracki Nathan; Marshall Nicholas M
Design of functional metalloproteins.
Nature 2009;460(7257):855-62.
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2009: Nagraj Nandini; Liu Juewen; Sterling Stephanie; Wu Jenny; Lu Yi
DNAzyme catalytic beacon sensors that resist temperature-dependent variations.
Chemical communications (Cambridge, England) 2009;(27):4103-5.
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2009: Zhang Jun-Long; Garner Dewain K; Liang Lei; Barrios David A; Lu Yi
Noncovalent modulation of pH-dependent reactivity of a Mn-salen cofactor in myoglobin with hydrogen peroxide.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(30):7481-9.
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2009: Liu Juewen; Cao Zehui; Lu Yi
Functional nucleic acid sensors.
Chemical reviews 2009;109(5):1948-98.
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2009: Mazumdar Debapriya; Nagraj Nandini; Kim Hee-Kyung; Meng Xiangli; Brown Andrea K; Sun Qian; Li Wei; Lu Yi
Activity, Folding and Z-DNA Formation of the 8-17 DNAzyme in the Presence of Monovalent Ions.
Journal of the American Chemical Society 2009;131(15):5506-15.
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2009: Brown Andrea K; Liu Juewen; He Ying; Lu Yi
Biochemical characterization of a uranyl ion-specific DNAzyme.
Chembiochem : a European journal of chemical biology 2009;10(3):486-92.
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2009: Clark Kevin M; van der Donk Wilfred A; Lu Yi
Expressed protein ligation for metalloprotein design and engineering.
Methods in enzymology 2009;462():97-115.
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2009: Cao Zehui; Tong Rong; Mishra Abhijit; Xu Weichen; Wong Gerard C L; Cheng Jianjun; Lu Yi
Reversible cell-specific drug delivery with aptamer-functionalized liposomes.
Angewandte Chemie (International ed. in English) 2009;48(35):6494-8.
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2009: Lu Yi; Liu Juewen; Mazumdar Debapriya
Nanoparticles/Dip stick.
Methods in molecular biology (Clifton, N.J.) 2009;535():223-39.
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2008: Park Jang-Ung; Lee Jung Heon; Paik Ungyu; Lu Yi; Rogers John A
Nanoscale patterns of oligonucleotides formed by electrohydrodynamic jet printing with applications in biosensing and nanomaterials assembly.
Nano letters 2008;8(12):4210-6.
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2008: Wang Zidong; Heon Lee Jung; Lu Yi
Highly sensitive "turn-on" fluorescent sensor for Hg2+ in aqueous solution based on structure-switching DNA.
Chemical communications (Cambridge, England) 2008;(45):6005-7.
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2008: Yeung Natasha; Lu Yi
One heme, diverse functions: using biosynthetic myoglobin models to gain insights into heme-copper oxidases and nitric oxide reductases.
Chemistry & biodiversity 2008;5(8):1437-48.
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2008: Shyr Margaret H S; Wernette Daryl P; Wiltzius Pierre; Lu Yi; Braun Paul V
DNA and DNAzyme-mediated 2D colloidal assembly.
Journal of the American Chemical Society 2008;130(26):8234-40.
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2008: Savelieff Masha G; Wilson Tiffany D; Elias Youssef; Nilges Mark J; Garner Dewain K; Lu Yi
Experimental evidence for a link among cupredoxins: red, blue, and purple copper transformations in nitrous oxide reductase.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(23):7919-24.
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2008: Dalavoy Tulika S; Wernette Daryl P; Gong Maojun; Sweedler Jonathan V; Lu Yi; Flachsbart Bruce R; Shannon Mark A; Bohn Paul W; Cropek Donald M
Immobilization of DNAzyme catalytic beacons on PMMA for Pb2+ detection.
Lab on a chip 2008;8(5):786-93.
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2008: Zhang Jun-Long; Garner Dewain K; Liang Lei; Chen Qian; Lu Yi
Protein scaffold of a designed metalloenzyme enhances the chemoselectivity in sulfoxidation of thioanisole.
Chemical communications (Cambridge, England) 2008;(14):1665-7.
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2008: Sieracki Nathan A; Hwang Hee Jung; Lee Michelle K; Garner Dewain K; Lu Yi
A temperature independent pH (TIP) buffer for biomedical biophysical applications at low temperatures.
Chemical communications (Cambridge, England) 2008;(7):823-5.
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2008: Yigit Mehmet Veysel; Mazumdar Debapriya; Lu Yi
MRI detection of thrombin with aptamer functionalized superparamagnetic iron oxide nanoparticles.
Bioconjugate chemistry 2008;19(2):412-7.
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2008: Kim Hee-Kyung; Li Jing; Nagraj Nandini; Lu Yi
Probing metal binding in the 8-17 DNAzyme by TbIII luminescence spectroscopy.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(28):8696-703.
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2007: Liu Juewen; Lu Yi
Colorimetric Cu2+ detection with a ligation DNAzyme and nanoparticles.
Chemical communications (Cambridge, England) 2007;(46):4872-4.
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2007: Denofrio Lauren A; Russell Brandy; Lopatto David; Lu Yi
Mentoring. Linking student interests to science curricula.
Science (New York, N.Y.) 2007;318(5858):1872-3.
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2007: Kim Hee-Kyung; Rasnik Ivan; Liu Juewen; Ha Taekjip; Lu Yi
Dissecting metal ion-dependent folding and catalysis of a single DNAzyme.
Nature chemical biology 2007;3(12):763-8.
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2007: Yigit Mehmet Veysel; Mazumdar Debapriya; Kim Hee-Kyung; Lee Jung Heon; Odintsov Boris; Lu Yi
Smart "turn-on" magnetic resonance contrast agents based on aptamer-functionalized superparamagnetic iron oxide nanoparticles.
Chembiochem : a European journal of chemical biology 2007;8(14):1675-8.
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2007: Wernette Daryl P; Mead Carolyn; Bohn Paul W; Lu Yi
Surface immobilization of catalytic beacons based on ratiometric fluorescent DNAzyme sensors: a systematic study.
Langmuir : the ACS journal of surfaces and colloids 2007;23(18):9513-21.
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2007: Liu Juewen; Lu Yi
A DNAzyme catalytic beacon sensor for paramagnetic Cu2+ ions in aqueous solution with high sensitivity and selectivity.
Journal of the American Chemical Society 2007;129(32):9838-9.
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2007: Liu Juewen; Lu Yi
Non-base pairing DNA provides a new dimension for controlling aptamer-linked nanoparticles and sensors.
Journal of the American Chemical Society 2007;129(27):8634-43.
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2007: Liu Juewen; Lee Jung Heon; Lu Yi
Quantum dot encoding of aptamer-linked nanostructures for one-pot simultaneous detection of multiple analytes.
Analytical chemistry 2007;79(11):4120-5.
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2007: Kim Hee-Kyung; Liu Juewen; Li Jing; Nagraj Nandini; Li Mingxi; Pavot Caroline M-B; Lu Yi
Metal-dependent global folding and activity of the 8-17 DNAzyme studied by fluorescence resonance energy transfer.
Journal of the American Chemical Society 2007;129(21):6896-902.
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2007: Lu Yi; Liu Juewen
Smart nanomaterials inspired by biology: dynamic assembly of error-free nanomaterials in response to multiple chemical and biological stimuli.
Accounts of chemical research 2007;40(5):315-23.
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2007: Liu Juewen; Brown Andrea K; Meng Xiangli; Cropek Donald M; Istok Jonathan D; Watson David B; Lu Yi
A catalytic beacon sensor for uranium with parts-per-trillion sensitivity and millionfold selectivity.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(7):2056-61.
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2007: Pfister Thomas D; Mirarefi Amir Y; Gengenbach Alan J; Zhao Xuan; Danstrom Connor; Conatser Nicole; Gao Yi-Gui; Robinson Howard; Zukoski Charles F; Wang Andrew H-J; Lu Yi
Kinetic and crystallographic studies of a redesigned manganese-binding site in cytochrome c peroxidase.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2007;12(1):126-37.
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2007: Lee Jung Heon; Wernette Daryl P; Yigit Mehmet V; Liu Juewen; Wang Zidong; Lu Yi
Site-specific control of distances between gold nanoparticles using phosphorothioate anchors on DNA and a short bifunctional molecular fastener.
Angewandte Chemie (International ed. in English) 2007;46(47):9006-10.
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2007: Liu Juewen; Lu Yi
Rational design of "turn-on" allosteric DNAzyme catalytic beacons for aqueous mercury ions with ultrahigh sensitivity and selectivity.
Angewandte Chemie (International ed. in English) 2007;46(40):7587-90.
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2006: Garner Dewain K; Vaughan Mark D; Hwang Hee Jung; Savelieff Masha G; Berry Steven M; Honek John F; Lu Yi
Reduction potential tuning of the blue copper center in Pseudomonas aeruginosa azurin by the axial methionine as probed by unnatural amino acids.
Journal of the American Chemical Society 2006;128(49):15608-17.
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2006: Lu Yi
Metalloprotein and metallo-DNA/RNAzyme design: current approaches, success measures, and future challenges.
Inorganic chemistry 2006;45(25):9930-40.
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2006: Liu Juewen; Mazumdar Debapriya; Lu Yi
A simple and sensitive "dipstick" test in serum based on lateral flow separation of aptamer-linked nanostructures.
Angewandte Chemie (International ed. in English) 2006;45(47):7955-9.
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2006: Lu Yi; Liu Juewen
Functional DNA nanotechnology: emerging applications of DNAzymes and aptamers.
Current opinion in biotechnology 2006;17(6):580-8.
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2006: Liu Juewen; Lu Yi
Design of asymmetric DNAzymes for dynamic control of nanoparticle aggregation states in response to chemical stimuli.
Organic & biomolecular chemistry 2006;4(18):3435-41.
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2006: Lu Yi
Biosynthetic inorganic chemistry.
Angewandte Chemie (International ed. in English) 2006;45(34):5588-601.
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2006: Zhao Xuan; Yeung Natasha; Russell Brandy S; Garner Dewain K; Lu Yi
Catalytic reduction of NO to N2O by a designed heme copper center in myoglobin: implications for the role of metal ions.
Journal of the American Chemical Society 2006;128(21):6766-7.
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2006: Hwang Hee Jung; Nagraj Nandini; Lu Yi
Spectroscopic characterizations of bridging cysteine ligand variants of an engineered Cu2(Scys)2 CuA azurin.
Inorganic chemistry 2006;45(1):102-7.
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2006: Wernette Daryl P; Swearingen Carla B; Cropek Donald M; Lu Yi; Sweedler Jonathan V; Bohn Paul W
Incorporation of a DNAzyme into Au-coated nanocapillary array membranes with an internal standard for Pb(ii) sensing.
The Analyst 2006;131(1):41-7.
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2006: Liu Juewen; Lu Yi
Preparation of aptamer-linked gold nanoparticle purple aggregates for colorimetric sensing of analytes.
Nature protocols 2006;1(1):246-52.
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2006: Liu Juewen; Lu Yi
Fluorescent DNAzyme biosensors for metal ions based on catalytic molecular beacons.
Methods in molecular biology (Clifton, N.J.) 2006;335():275-88.
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2006: Liu Juewen; Lu Yi
Multi-fluorophore fluorescence resonance energy transfer for probing nucleic acids structure and folding.
Methods in molecular biology (Clifton, N.J.) 2006;335():257-71.
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2005: Liu Juewen; Lu Yi
Fast colorimetric sensing of adenosine and cocaine based on a general sensor design involving aptamers and nanoparticles.
Angewandte Chemie (International ed. in English) 2005;45(1):90-4.
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2005: Wang Ningyan; Zhao Xuan; Lu Yi
Role of heme types in heme-copper oxidases: effects of replacing a heme b with a heme o mimic in an engineered heme-copper center in myoglobin.
Journal of the American Chemical Society 2005;127(47):16541-7.
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2005: Hwang Hee Jung; Carey James R; Brower Evan T; Gengenbach Alan J; Abramite Joseph A; Lu Yi
Blue ferrocenium azurin: an organometalloprotein with tunable redox properties.
Journal of the American Chemical Society 2005;127(44):15356-7.
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2005: Liu Juewen; Wernette Daryl P; Lu Yi
Proofreading and error removal in a nanomaterial assembly.
Angewandte Chemie (International ed. in English) 2005;44(44):7290-3.
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2005: Liu Juewen; Lu Yi
Stimuli-responsive disassembly of nanoparticle aggregates for light-up colorimetric sensing.
Journal of the American Chemical Society 2005;127(36):12677-83.
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2005: Nelson Kevin E; Bruesehoff Peter J; Lu Yi
In vitro selection of high temperature Zn(2+)-dependent DNAzymes.
Journal of molecular evolution 2005;61(2):216-25.
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2005: Shaikh Kashan A; Ryu Kee Suk; Goluch Edgar D; Nam Jwa-Min; Liu Juewen; Thaxton C Shad; Chiesl Thomas N; Barron Annelise E; Lu Yi; Mirkin Chad A; Liu Chang
A modular microfluidic architecture for integrated biochemical analysis.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(28):9745-50.
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2005: Chang In-Hyoung; Tulock Joseph J; Liu Juewen; Kim Won-Suk; Cannon Donald M; Lu Yi; Bohn Paul W; Sweedler Jonathan V; Cropek Donald M
Miniaturized lead sensor based on lead-specific DNAzyme in a nanocapillary interconnected microfluidic device.
Environmental science & technology 2005;39(10):3756-61.
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2005: Hwang Hee Jung; Berry Steven M; Nilges Mark J; Lu Yi
Axial methionine has much less influence on reduction potentials in a CuA center than in a blue copper center.
Journal of the American Chemical Society 2005;127(20):7274-5.
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2005: Zhao Xuan; Nilges Mark J; Lu Yi
Redox-dependent structural changes in an engineered heme-copper center in myoglobin: insights into chloride binding to CuB in heme copper oxidases.
Biochemistry 2005;44(17):6559-64.
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2005: Lu Yi
Design and engineering of metalloproteins containing unnatural amino acids or non-native metal-containing cofactors.
Current opinion in chemical biology 2005;9(2):118-26.
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2005: Pfister Thomas D; Ohki Takahiro; Ueno Takafumi; Hara Isao; Adachi Seiji; Makino Yumiko; Ueyama Norikazu; Lu Yi; Watanabe Yoshihito
Monooxygenation of an aromatic ring by F43W/H64D/V68I myoglobin mutant and hydrogen peroxide. Myoglobin mutants as a model for P450 hydroxylation chemistry.
The Journal of biological chemistry 2005;280(13):12858-66.
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2005: Zhao Xuan; Yeung Natasha; Wang Zhilin; Guo Zijian; Lu Yi
Effects of metal ions in the CuB center on the redox properties of heme in heme-copper oxidases: spectroelectrochemical studies of an engineered heme-copper center in myoglobin.
Biochemistry 2005;44(4):1210-4.
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2005: Swearingen Carla B; Wernette Daryl P; Cropek Donald M; Lu Yi; Sweedler Jonathan V; Bohn Paul W
Immobilization of a catalytic DNA molecular beacon on Au for Pb(II) detection.
Analytical chemistry 2005;77(2):442-8.
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2004: Liu Juewen; Lu Yi
Accelerated color change of gold nanoparticles assembled by DNAzymes for simple and fast colorimetric Pb2+ detection.
Journal of the American Chemical Society 2004;126(39):12298-305.
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2004: Carey James R; Ma Steven K; Pfister Thomas D; Garner Dewain K; Kim Hyeon K; Abramite Joseph A; Wang Zhilin; Guo Zijian; Lu Yi
A site-selective dual anchoring strategy for artificial metalloprotein design.
Journal of the American Chemical Society 2004;126(35):10812-3.
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2004: Hwang Hee Jung; Lu Yi
pH-dependent transition between delocalized and trapped valence states of a CuA center and its possible role in proton-coupled electron transfer.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(35):12842-7.
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2004: Liu Juewen; Lu Yi
Colorimetric biosensors based on DNAzyme-assembled gold nanoparticles.
Journal of fluorescence 2004;14(4):343-54.
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2004: Ralle Martina; Berry Steven M; Nilges Mark J; Gieselman Matt D; van der Donk Wilfred A; Lu Yi; Blackburn Ninian J
The selenocysteine-substituted blue copper center: spectroscopic investigations of Cys112SeCys Pseudomonas aeruginosa azurin.
Journal of the American Chemical Society 2004;126(23):7244-56.
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2004: Hwang Hee Jung; Ang Majorie; Lu Yi
Determination of reduction potential of an engineered Cu(A) azurin by cyclic voltammetry and spectrochemical titrations.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2004;9(4):489-94.
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2004: Hwang Hee Jung; Lu Yi
Spectroscopic evidence for interactions between hexacyanoiron(II/III) and an engineered purple CuA azurin.
Journal of inorganic biochemistry 2004;98(5):797-802.
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2004: Liu Juewen; Lu Yi
Adenosine-dependent assembly of aptazyme-functionalized gold nanoparticles and its application as a colorimetric biosensor.
Analytical chemistry 2004;76(6):1627-32.
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2003: Liu Juewen; Lu Yi
Improving fluorescent DNAzyme biosensors by combining inter- and intramolecular quenchers.
Analytical chemistry 2003;75(23):6666-72.
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2003: Feng Manliang; Tachikawa Hiroyasu; Wang Xiaotang; Pfister Thomas D; Gengenbach Alan J; Lu Yi
Resonance Raman spectroscopy of cytochrome c peroxidase variants that mimic manganese peroxidase.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2003;8(7):699-706.
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2003: Berry Steven M; Ralle Martina; Low Donald W; Blackburn Ninian J; Lu Yi
Probing the role of axial methionine in the blue copper center of azurin with unnatural amino acids.
Journal of the American Chemical Society 2003;125(29):8760-8.
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2003: Brown Andrea K; Li Jing; Pavot Caroline M-B; Lu Yi
A lead-dependent DNAzyme with a two-step mechanism.
Biochemistry 2003;42(23):7152-61.
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2003: Liu Juewen; Lu Yi
A colorimetric lead biosensor using DNAzyme-directed assembly of gold nanoparticles.
Journal of the American Chemical Society 2003;125(22):6642-3.
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2003: Lu Yi; Liu Juewen; Li Jing; Bruesehoff Peter J; Pavot Caroline M-B; Brown Andrea K
New highly sensitive and selective catalytic DNA biosensors for metal ions.
Biosensors & bioelectronics 2003;18(5-6):529-40.
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2003: Sigman Jeffrey A; Kim Hyeon K; Zhao Xuan; Carey James R; Lu Yi
The role of copper and protons in heme-copper oxidases: kinetic study of an engineered heme-copper center in myoglobin.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):3629-34.
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2003: Perera Roshan; Sono Masanori; Sigman Jeffrey A; Pfister Thomas D; Lu Yi; Dawson John H
Neutral thiol as a proximal ligand to ferrous heme iron: implications for heme proteins that lose cysteine thiolate ligation on reduction.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):3641-6.
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2002: Liu Juewen; Lu Yi
FRET study of a trifluorophore-labeled DNAzyme.
Journal of the American Chemical Society 2002;124(51):15208-16.
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2002: Lu Yi
New transition-metal-dependent DNAzymes as efficient endonucleases and as selective metal biosensors.
Chemistry (Weinheim an der Bergstrasse, Germany) 2002;8(20):4589-96.
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2002: Bruesehoff Peter J; Li Jing; Augustine Anthony J; Lu Yi
Improving metal ion specificity during in vitro selection of catalytic DNA.
Combinatorial chemistry & high throughput screening 2002;5(4):327-35.
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2002: Berry Steven M; Gieselman Matt D; Nilges Mark J; van Der Donk Wilfred A; Lu Yi
An engineered azurin variant containing a selenocysteine copper ligand.
Journal of the American Chemical Society 2002;124(10):2084-5.
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2001: Pfister T D; Gengenbach A J; Syn S; Lu Y
The role of redox-active amino acids on compound I stability, substrate oxidation, and protein cross-linking in yeast cytochrome C peroxidase.
Biochemistry 2001;40(49):14942-51.
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2001: Lu Y; Berry S M; Pfister T D
Engineering novel metalloproteins: design of metal-binding sites into native protein scaffolds.
Chemical reviews 2001;101(10):3047-80.
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2001: Sigman J A; Wang X; Lu Y
Coupled oxidation of heme by myoglobin is mediated by exogenous peroxide.
Journal of the American Chemical Society 2001;123(28):6945-6.
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2001: Yin Y; Lu Y; Xia Y
A self-assembly approach to the formation of asymmetric dimers from monodispersed spherical colloids.
Journal of the American Chemical Society 2001;123(4):771-2.
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2000: Berry S M; Wang X; Lu Y
Ligand replacement study at the His120 site of purple CuA azurin.
Journal of inorganic biochemistry 2000;78(1):89-95.
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2000: Li J; Zheng W; Kwon A H; Lu Y
In vitro selection and characterization of a highly efficient Zn(II)-dependent RNA-cleaving deoxyribozyme.
Nucleic acids research 2000;28(2):481-8.
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1999: Gengenbach A; Syn S; Wang X; Lu Y
Redesign of cytochrome c peroxidase into a manganese peroxidase: role of tryptophans in peroxidase activity.
Biochemistry 1999;38(35):11425-32.
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1999: Sigman J A; Pond A E; Dawson J H; Lu Y
Engineering cytochrome c peroxidase into cytochrome P450: a proximal effect on heme-thiolate ligation.
Biochemistry 1999;38(34):11122-9.
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1999: Wang X; Lu Y
Proton NMR investigation of the heme active site structure of an engineered cytochrome c peroxidase that mimics manganese peroxidase.
Biochemistry 1999;38(28):9146-57.
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1999: Wilson S P; Yeomans D C; Bender M A; Lu Y; Goins W F; Glorioso J C
Antihyperalgesic effects of infection with a preproenkephalin-encoding herpes virus.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3211-6.
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1997: Lu Y; Valentine J S
Engineering metal-binding sites in proteins.
Current opinion in structural biology 1997;7(4):495-500.
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1997: Yeung B K; Wang X; Sigman J A; Petillo P A; Lu Y
Construction and characterization of a manganese-binding site in cytochrome c peroxidase: towards a novel manganese peroxidase.
Chemistry & biology 1997;4(3):215-21.
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